1. Posterior reversible encephalopathy syndrome in a patient of organophosphate poisoning
- Author
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Shrinivas Deshpande, Rajesh S Phatake, Nagaraj Tankasali, Manikanth Lodaya, and Sameer Desai
- Subjects
medicine.medical_specialty ,posterior reversible encephalopathy syndrome ,Pralidoxime ,medicine.diagnostic_test ,business.industry ,Sedation ,Posterior reversible encephalopathy syndrome ,Case Report ,Critical Care and Intensive Care Medicine ,medicine.disease ,Irritability ,Organophosphate poisoning ,Organophosphorous poisoning ,Hyperintensity ,Surgery ,poisoning ,Hemiparesis ,Anesthesia ,Magnetic resonance imaging of the brain ,medicine ,medicine.symptom ,business ,medicine.drug - Abstract
A 32-year-old male presented with a history of consuming some organophosphorous compound with suicidal intention. He was treated with atropine, pralidoxime, ventilator support. During stay patient had persistent irritability, tachycardiaand hypertension despite sedation and labetalol infusion. He developed headache, visual blurring hemiparesis and focal seizures. Magnetic resonance imaging of the brain revealed multifocal hyperintensities mainly in subcortical areas of parietal and occipital regions in T2-weighted images, with increased values of Apparent Diffusion Coefficient, suggesting posterior reversible encephalopathy syndrome (PRES). The possibilities of PRES caused by organophosphorous poisoning either due to hypertension caused by autonomic deregulation or direct neurological toxicity has been discussed.
- Published
- 2014