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15 results on '"Naftalin, Claire M."'

1. A blood RNA transcriptome signature for COVID-19

Author

Kwan, Philip Kam Weng, Cross, Gail B., Naftalin, Claire M., Ahidjo, Bintou A., Mok, Chee Keng, Fanusi, Felic, Permata Sari, Intan, Chia, Siok Ching, Kumar, Shoban Krishna, Alagha, Rawan, Tham, Sai Meng, Archuleta, Sophia, Sessions, October M., Hibberd, Martin L., and Paton, Nicholas I.

Published
2021
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5. Discrepant serological findings in SARS‐CoV‐2 PCR negative, hospitalised patients with fever and acute respiratory symptoms during the pandemic

Author

Cross, Gail Brenda, primary, Naftalin, Claire M., additional, Ngiam, Jinghao Nicholas, additional, Bagdasarian, Natasha, additional, Poh, Chek Meng, additional, Goh, Yun Shan, additional, Chia, Wan Ni, additional, Amrun, Siti Naqiah, additional, Tham, Sai Meng, additional, Teng, Hazel, additional, Alagha, Rawan, additional, Kumar, Shoban Krishna, additional, Tan, Shaun Shi Yan, additional, Wang, Lin Fa, additional, Tambyah, Paul Anantharajah, additional, Renia, Laurent, additional, Fisher, Dale, additional, and Ng, Lisa F.P., additional

Published
2022
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7. Additional file 1 of A blood RNA transcriptome signature for COVID-19

Author

Kwan, Philip Kam Weng, Cross, Gail B., Naftalin, Claire M., Ahidjo, Bintou A., Mok, Chee Keng, Fanusi, Felic, Permata Sari, Intan, Chia, Siok Ching, Kumar, Shoban Krishna, Alagha, Rawan, Tham, Sai Meng, Archuleta, Sophia, Sessions, October M., Hibberd, Martin L., and Paton, Nicholas I.

Subjects
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, ComputingMilieux_COMPUTERSANDEDUCATION, Data_FILES, ComputerApplications_COMPUTERSINOTHERSYSTEMS
Abstract

Additional file 1. Supplementary tables and figures.

Published
2021
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8. Additional file 1 of A blood RNA transcript signature for TB exposure in household contacts

Author

Kwan, Philip Kam Weng, Balamurugan Periaswamy, Sessions, Paola Florez De, Wenwei Lin, Molton, James S., Naftalin, Claire M., Naim, Ahmad Nazri Mohamed, Hibberd, Martin L., and Paton, Nicholas I.

Abstract

Additional file 1 Supplementary Figure 1. Panel A: Comparison of the 186 differentially expressed genes in contacts with 792 genes differentially expressed genes in patients with active TB (both compared to healthy controls) yielded 141 overlap genes. Panel B: Log2fold change expression values of the 141 overlap genes for Contacts and active TB (Wilcoxon signed rank test p 1 or

Published
2020
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9. Sub-clinical abnormalities detected by PET/MRI in household tuberculosis contacts

Author

Molton, James S., primary, Thomas, Benjamin A., additional, Pang, Yan, additional, Khor, Lih Kin, additional, Hallinan, James, additional, Naftalin, Claire M., additional, Totman, John J., additional, Townsend, David W., additional, Lim, Tow Keang, additional, Chee, Cynthia Bin Eng, additional, Wang, Yee Tang, additional, and Paton, Nicholas I., additional

Published
2019
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10. Coadministration of Allopurinol To Increase Antimycobacterial Efficacy of Pyrazinamide as Evaluated in a Whole-Blood Bactericidal Activity Model

Author

Naftalin, Claire M., primary, Verma, Rupangi, additional, Gurumurthy, Meera, additional, Lu, Qingshu, additional, Zimmerman, Matthew, additional, Yeo, Benjamin Chaik Meng, additional, Tan, Kin Hup, additional, Lin, Wenwei, additional, Yu, Buduo, additional, Dartois, Véronique, additional, and Paton, Nicholas I., additional

Published
2017
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11. Activity of faropenem with and without rifampicin against Mycobacterium tuberculosis: evaluation in a whole-blood bactericidal activity trial

Author

Gurumurthy, Meera, primary, Verma, Rupangi, additional, Naftalin, Claire M., additional, Hee, Kim Hor, additional, Lu, Qingshu, additional, Tan, Kin Hup, additional, Issac, Simi, additional, Lin, Wenwei, additional, Tan, Angelia, additional, Seng, Kok-Yong, additional, Lee, Lawrence Soon-U., additional, and Paton, Nicholas I., additional

Published
2017
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15. Three different patterns of CD4 recovery in a cohort of Chinese HIV patients following antiretroviral therapy - a five-year observational study.

Author

Naftalin, Claire M, Wong, Ngai Sze, Chan, Denise Pc, Wong, Ka Hing, Reidpath, Daniel D, Lee, Shui Shan, and Chan, Denise P C

Subjects
RNA analysis, ASIANS, HIV, HIV infections, VIRAL load, HIGHLY active antiretroviral therapy, TREATMENT effectiveness, ANTI-HIV agents, CD4 lymphocyte count
Abstract

To explore the heterogeneity of CD4 responses following highly active antiretroviral therapy, the patterns of CD4 recovery of HIV-1-infected Chinese patients who have been on their first antiretroviral regimen for ≥5 years were analysed. The CD4 trajectories were traced, smoothed and differentiated into three defined profiles. Half (56.3%) were 'satisfactory responders', with CD4 gain of >100 cells/μL and a peak of >350 cells/μL, plateauing before the end of Year 5. Thirty-three (24.4%) were 'continuing responders' whose CD4 rise persisted at Year 4-5. The remaining 26 (19.3%) were 'poor responders'. Presentation with AIDS before therapy was common not just among 'poor' but also paradoxically the 'continuing' responders. While a majority had responded well to antiretroviral therapy, older patients and those with AIDS diagnosis before initiation of therapy may never achieve a satisfactory level even with effective treatment. Categorization of HIV patients by their CD4 trajectory may support the prediction of immunological outcome over time, and ultimately inform treatment choices. [ABSTRACT FROM AUTHOR]

Published
2015
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