Search

Your search keyword '"Naden MG"' showing total 2 results
Start Over Author "Naden MG"
2 results on '"Naden MG"'

1. The in-vitro activity of three long-acting cephalosporins against Bacteroides fragilis, Peptostreptococcus species and Clostridium perfringens.

Author

Watt B and Naden MG

Subjects
Cefamandole pharmacology, Cefonicid, Clindamycin pharmacology, Microbial Sensitivity Tests, Bacteroides fragilis drug effects, Cefamandole analogs & derivatives, Cefotetan pharmacology, Ceftriaxone pharmacology, Clostridium perfringens drug effects, Peptostreptococcus drug effects
Abstract

The in-vitro activity of three long-acting cephalosporins (cefotetan, cefonicid and ceftriaxone) was compared against 206 clinical isolates of Bacteroides fragilis, Peptostreptococcus species and Clostridium perfringens, using an agar dilution procedure to determine minimum inhibitory concentrations (MICs). Clindamycin was included as a comparator. Cefotetan was much more active than the two other cephalosporins against strains of Bacteroides fragilis (MIC90 16 mg/l compared with greater than 128 mg/l for the other two agents). Cefotetan also demonstrated superior activity against anaerobic cocci. All three compounds showed good activity against strains of Clostridium perfringens. Clindamycin was active against all of the test strains.

Published
1988

Catalog

Books, media, physical & digital resources
See catalog results