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Your search keyword '"Nachbar, Renato Tadeu"' showing total 17 results
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17 results on '"Nachbar, Renato Tadeu"'

1. Gut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice

Author

Daniel, Noëmie, Nachbar, Renato Tadeu, Tran, Thi Thu Trang, Ouellette, Adia, Varin, Thibault Vincent, Cotillard, Aurélie, Quinquis, Laurent, Gagné, Andréanne, St-Pierre, Philippe, Trottier, Jocelyn, Marcotte, Bruno, Poirel, Marion, Saccareau, Mathilde, Dubois, Marie-Julie, Joubert, Philippe, Barbier, Olivier, Koutnikova, Hana, and Marette, André

Published
2022
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2. Changes in Skeletal Muscle Protein Metabolism Signaling Induced by Glutamine Supplementation and Exercise

Author

Rodrigues Junior, Carlos Flores, primary, Murata, Gilson Masahiro, additional, Gerlinger-Romero, Frederico, additional, Nachbar, Renato Tadeu, additional, Marzuca-Nassr, Gabriel Nasri, additional, Gorjão, Renata, additional, Vitzel, Kaio Fernando, additional, Hirabara, Sandro Massao, additional, Pithon-Curi, Tania Cristina, additional, and Curi, Rui, additional

Published
2023
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3. Maternal low-protein diet reduces skeletal muscle protein synthesis and mass via Akt-mTOR pathway in adult rats

Author

de Vasconcelos, Diogo Antonio Alves, primary, Nachbar, Renato Tadeu, additional, Pinheiro, Carlos Hermano, additional, do Amaral, Cátia Lira, additional, Crisma, Amanda Rabello, additional, Vitzel, Kaio Fernando, additional, Abreu, Phablo, additional, Alonso-Vale, Maria Isabel, additional, Lopes, Andressa Bolsoni, additional, Bento-Santos, Adriano, additional, Falcão-Tebas, Filippe, additional, de Santana, David Filipe, additional, do Nascimento, Elizabeth, additional, Curi, Rui, additional, Pithon-Curi, Tania Cristina, additional, Hirabara, Sandro Massao, additional, and Leandro, Carol Góis, additional

Published
2022
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4. Abstract 19042: Role for Leptin Signaling in Experimental Group 2 Pulmonary Hypertension Due to Metabolic Syndrome

Author

Ranchoux, Benoit, Potus, François, Bourgeois, Alice, Nadeau, Valérie, Paulin, Roxanne, Tremblay, Ève, Coté, Nancy, Abu-alhayja, Rami, Dumais, Valérie, Nachbar, Renato Tadeu, Tastet, Lionel, Dahou, Abdelaziz, Breuils-Bonnet, Sandra, Lajoie, Annie-Christine, Marette, André, Pibarot, Philippe, Dupuis, Jocelyn, Boucherat, Olivier, Provencher, Steeve, Archer, Stephen, and Bonnet, Sébastien

Published
2017

13. Local Injections of Adipose-Derived Mesenchymal Stem Cells Modulate Inflammation and Increase Angiogenesis Ameliorating the Dystrophic Phenotype in Dystrophin-Deficient Skeletal Muscle

Author

da Justa Pinheiro, Carlos Hermano, primary, de Queiroz, Jean César Farias, additional, Guimarães-Ferreira, Lucas, additional, Vitzel, Kaio Fernando, additional, Nachbar, Renato Tadeu, additional, de Sousa, Luís Gustavo Oliveira, additional, de Souza-Jr, Alcione Lescano, additional, Nunes, Maria Tereza, additional, and Curi, Rui, additional

Published
2011
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17. Local injections of adipose-derived mesenchymal stem cells modulate inflammation and increase angiogenesis ameliorating the dystrophic phenotype in dystrophin-deficient skeletal muscle.

Author

Pinheiro CH, de Queiroz JC, Guimarães-Ferreira L, Vitzel KF, Nachbar RT, de Sousa LG, de Souza AL Jr, Nunes MT, and Curi R

Subjects
Adipose Tissue cytology, Animals, Biomarkers metabolism, Cytokines metabolism, Dystrophin metabolism, Inflammation Mediators metabolism, Injections, Macrophages metabolism, Male, Mesenchymal Stem Cells metabolism, Mice, Mice, Inbred C57BL, Muscular Dystrophy, Animal therapy, Myogenin metabolism, Phenotype, Reactive Oxygen Species metabolism, Transforming Growth Factor beta1 metabolism, Vascular Endothelial Growth Factor A metabolism, Dystrophin deficiency, Inflammation pathology, Mesenchymal Stem Cell Transplantation, Mesenchymal Stem Cells cytology, Muscle, Skeletal pathology, Muscular Dystrophy, Animal pathology, Neovascularization, Physiologic
Abstract

The effects of adipose-derived mesenchymal stem cells (ADMSC) transplantation on degeneration, regeneration and skeletal muscle function were investigated in dystrophin-deficient mice (24-week-old). ADMSC transplantation improved muscle strength and, resistance to fatigue. An increase in fiber cross-sectional area and in the number of fibers with centralized nuclei and augment of myogenin content were observed. In ADMSC-treated muscles a decrease in muscle content of TNF-α, IL-6 and oxidative stress measured by Amplex(®) reagent were observed. The level of TGF-β1 was lowered whereas that of VEGF, IL-10 and IL-4 were increased by ADMSC treatment. An increase in markers of macrophage M1 (CD11 and F4-80) and a decrease in T lymphocyte marker (CD3) and arginase-1 were also observed in ADMSCs-treated dystrophic muscle. No change was observed in iNOS expression. Increased phosphorylation of Akt, p70S6k and 4E-BP1 was found in dystrophic muscles treated with ADMSC. These results suggest that ADMSC transplantation modulates inflammation and improves muscle tissue regeneration, ameliorating the dystrophic phenotype in dystrophin-deficient mice.

Published
2012
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