Search

A case is reported of an old female patient with exogenic allergic alveolitis which was first diagnosed as pneumonia progressing in the presence of long-term and intensive antibiotic treatment. Detailed analysis of the case history gave grounds for suspected drug-related exogenic allergic alveolitis. Discontinuation of antibiotics, administration of glucocorticoids and antiplatelet drugs led to recovery.

Priorities and directions of development of the Russian economy are connected with the eastern territories. The purpose of the study is to the identify key problems and substantiate indicators of the hygienic and epidemiological welfare of the population of Siberia. Two blocks of characteristics (“public health” and “environment”) are considered in dynamics for 5 years in the context of the subjects of the Siberian Federal District. Four groups of territories differed in terms of the incidence rate and the average life expectancy (ALE) using cluster analysis. It is shown that ALE depends on economic indicators. The incidence is associated with the amount of gross pollutant emissions in the atmospheric air (r = 0.83–0.96; p < 0.001). The assessment of the influence of the habitat on the health of the population at the level of the macroregion allowed to substantiate the hierarchy of the most significant factors. More than 98 % of the environmentally related component of morbidity is associated with the amount of gross emissions of harmful substances in the air (the contribution was 69 %), the provision of the population with doctors (12.6 %) and inpatient beds (6.7 %), the gross regional product (6.5 %), clean water consumption (3 %) and average per capita income (0.8 %). In conclusion, for the successful implementation of preventive strategies, an important stage is the development of a set of solutions for the effective use of resources available in the region (financial, personnel, medical, rehabilitation).

The article presents important medico-ecological problems: preservation of an effect of influence of air pollution in the subsequent generations; environmental and medical consequences of the cumulative ecological danger; taking into account regional features at the harmonization of hygienic standards; use of modern approaches to formation of target preventive programs. Relevance of these problems is observed on the example of Irkutsk region. Irkutsk region is one of the largest advanced industrial subjects of Russian Federation. The leading industries are energy, pulp-and-paper and chemical, wood and woodworking, nonferrous metallurgy, mechanical engineering. Concentration of the industry in the south of the region has led to high man-caused environmental load. Under conditions of reduced ability to self-purification of environmental objects this fact results in formation of zones of ecological trouble. Environmental and medicosocial problems occurring in a long-term technogenic mercury pollution are very important and require more systematic studies. Bratsk water reservoir is strongly polluted by technogenic Hg. Among rural population living near the toxicant sources the signs of unfavorable mercury effects have been revealed: mercury microcirculation in the organism (10,5 % of cases with group level urinary mercury > 5,2 microg/l), disorders of vegetative nervous system (87 % in intact group vs 43 % in the group of comparison; р ≤ 0,05) and pathology of thyroid glands (14,6 % children in intact group vs 8,1 % in the group of comparison; р ≤ 0,05). The aims of ecological medicine must include prevention as well as safe remediation and translational therapeutic intervention in human populations after exposures. The conception of development of the programs aimed at the coordination of activity of preventing ecologically caused losses was proposed.

The aim of study was a hygienic assessment on sanitary and chemical, microbiological indicators of food and the food staples, realized in the territory of the Buryat Republic during 2008-2012. Preparation for processing of primary data and the subsequent statistical analysis made with Excel and the integrated package STATISTICA 6.0. Calculation of percent of tests of hygienic standards not conforming to requirements (%) on areas and as a whole on the republic is carried out. The specified sizes are determined as for separate years, and on the average for the period. To average values 95% confidential intervals (CI) are calculated. As significant deviations from the average levels the sizes which are going out of CI were considered. The performed result of assessment of the laboratory studies may testify that the stable high percent of the samples which don't accord to the normative in the sanitary-chemical indices is available at present. Using the cluster analyses allowed to reveal that according to the sanitary-chemical indices 52,4 % of all the regions in which the portion of the non-standard samples was found to be in the range of 95% confidence interval (CI) [6,5-9,0] % of the average level have formed the more numerous (1st) cluster. The second cluster consisted of the Zaigrayevskiy and Bichurskiy regions in which the statistically significant increase in the prevalence of the non-standard samples was revealed. In 5 regions and the capital of Republic (Ulan-Ude) in the third cluster the most significant percent of the samples which don't accord to the hygienic claims (CI [15,0-29,0] %) is continuously registered. The fourth cluster consisted of three regions situated in the northern part of Buryat Republic in which the non-standard samples are extremely rare revealed (CI [0,5-2,2] %). The samples portion which don't accord to the hygienic normative in the microbiological indices was found to increase by 1,4-fold compared to the 2009-2011 years and amounted 3,8 % in 2012 year. The analysis based on the territorial factor has shown that the high levels of the non-standard samples of the food products in the microbiological indices were found to be in the regions of the first cluster: Eravninskiy, Mukhorshibirskiy, Kabanskiy and Ulan-Ude (CI [5,1-7,8] %), the last revealed level is the regions of the third cluster: Zakamenskiy, Bichurskiy, Barguzinskiy, Kurumkanskiy, Okinskiy, Bauntovskiy (CI [0,10-0,24] %). The control of microbiological safety allowed to reveal the most significant, in epidemic relation, food products: milk, meat, fish products, the products of children's food as well as the poultry products.

The prevalence of the bronchial asthma (BA) and the perennial allergic rhinitis (CAR), according to the questionnaire and medical examination, adolescents living in the industrial center of Irkutsk region, was 68 ± 3,4 per 100 patients. The most informative factors were: a positive skin prick test, detectable by skin testing, frequent respiratory infections in the history of passive smoking and family history.

The article reviews the main problem, of environmental hygiene and medical ecology — the absence of unity of methodological approaches to the detection of environmental health, disorders (EHD).

At present the pathology of laryngeal and respiratory organs is known to prevail in the structure of the child and adolescent morbidity in the industrial centers of the northern and eastern regions of the country and their proportion reaches 70 %. The disease symptoms of the respiratory tracts (the obstacle nose, discomfort and throat tickling as well as the hoarseness) and especially their complications may lead to the decrease in the life quality of children and adolescents. Taking into account that at present time it is impossible to remove technogenic air pollution totally, the complex studies on revealing the unfavorable factors, which may influence the organisms of the children and adolescents, are known to be the prior task of the preventive medicine. The aim of the study was to examine the frequency chronic respiratory pathology and influence on the adolescents life quality of industrial centers of Irkutsk region with different levels of technogenic pollution. 410 adolescents (14-17 years) for a long time living in the regions with the different air pollution levels air with the developed oil-chemical and industries were examined. The differences in the structure of chronic respiratory pathology were revealed in the examined adolescents: under conditions of the air pollution with a complex of chemical compounds with a high Hasard Index (HI = 17) the respiratory diseases prevail, and with the medium level (HI = 3,6) the nasal diseases prevail. It was found that that about 12,6 % of the morbidity variability in the category of the respiratory organs, in particular the throat pathology in the teenagers may be correlated with the air pollution. The more significant factors of forming the chronic respiratory pathology were found to be the health state, characterized by the laboratory indices (common microbial number of the nasal cavity and the pharynx; activity of lysocyme); chemical inhalation exposure; the work of the parents under harmful conditions during the period before child birth. The study results may be considered as the basis for the optimization of the approaches to the diagnostics and prevention of the respiratory pathology of adolescents.