300 results on '"N. Kuzmin"'
Search Results
2. Analysis of somatometric parameters of children with recurrent subluxations of C1–C2 vertebrae
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E. P. Fedorova, V. N. Kuzmin, L. A. Goncharova, N. Yu. Tanyushcheva, A. M. Kurkin, and M. R. Alimusaeva
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General Medicine - Abstract
Introduction. The problem of instability in the cervical spine in children has been repeatedly discussed in the medical literature and has become the subject of discussion. This is due to a significant increase in the number and recurrence of subluxations in the C1–C2 segment. An assumption is made about the relationship of this pathology with systemic connective tissue dysplasia, but evidence-based studies are required.Aim. To make a statistical analysis of individual somatometric indicators in children with recurrent subluxations of the C1–C2 vertebrae and signs of connective tissue dysplasia.Materials and methods. The analysis of measurements of selected body parameters in pre-pubertal children with acute and recurrent torticollis against the background of systemic connective tissue dysplasia was carried out. The data of 186 children aged 9–11 years in comparative groups for the period 2016–2021 were studied. Modern methods of statistics were used.Results. Dependences were obtained confirming the hypothesis of the relationship between asthenic physique (high height, low weight and chest circumference) and recurrent dislocations in the C1–C2 segmentConclusions. When comparing the average values for two independent samples made up of the indicators of the main group and the comparison group, the conclusion obtained during visual examination and somatometric examination of patients diagnosed with torticollis at admission to the hospital was confirmed: relapses are inherent in children with high growth, low weight, smaller chest circumference and smaller wrist circumference.
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- 2022
3. Active screening technological model of cardiac rhythm disturbances (experience of Moscow polyclinic)
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Elena V. Sorokina, Nadezhda P. Lyamina, Andrey A. Tyazhelnikov, Olga A. Mamontova, and Pavel N. Kuzmin
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Introduction. This article is devoted to the study of the structure of cardiac arrhythmias detected in the process of active screening using a portable ECG recorder in patients of the State Budgetary Institution of Healthcare "Consultative and Diagnostic Polyclinic No. 121 of the DZM" (hereinafter – KDP No. 121). Carried out as part of the project of the Department of Health of the city of Moscow "Scientific laboratory" Moscow Polyclinic ". Materials and methods. In a continuous cross-sectional screening study using a Cardiochair with a built-in electrocardiograph, in which the model of active screening of cardiac arrhythmias was implemented, all interested patients of the polyclinic took part: before seeing a doctor or receiving any medical procedure from 01/14/2022 to 08/03/2022 in KDP No. 121. Results. The study involved 5352 patients aged 18 to 105 years: men – 1723 (32.2%), women – 3629 (67.8%). Based on the results of the analysis of the obtained ECGs, 1610 HPS were detected: sinus tachycardia in 1324 (24%), bradycardia in 25 (1.4%), ventricular extrasystole in 135 (2%), supraventricular extrasystole in 33 (2%), atrial fibrillation in 118 (2%) – permanent AF in 62 (52%), paroxysmal AF in 56 patients (48%). In addition, interval changes were recorded: PQ shortening in 762 (14%) patients, PQ prolongation in 89 (1.7%), QRS widening in 545 (10%), QTc prolongation in 387 (7%). It was found that with age, adherence to ECG screening in men decreases, in women it increases. The most important advantage of the technological screening model using the Cardiochair with a built-in electrocardiograph was the timely verification of cardiac arrhythmias in patients, including primary patients. ECG data with interpretation was automatically displayed in the EMIAS patient's electronic medical record. Conclusions. The active screening of cardiac arrhythmias using the Cardiochair with an integrated electrocardiograph in KDP No. 121 is an example of the use of a digital health technology model for early diagnosis and management of chronic conditions for health management purposes.
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- 2022
4. Results of Comparative Studies of Treatment Processes of Some Types of Biomass by Wet and Oxidative Torrefaction Methods
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S. N. Kuzmin, R. L. Isemin, A. V. Mikhalev, O. Yu. Milovanov, D. V. Klimov, N. S. Muratova, V. S. Kokh-Tatarenko, and A. V. Nebyvayev
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Fuel Technology ,Geochemistry and Petrology ,General Chemical Engineering ,Energy Engineering and Power Technology - Published
- 2022
5. Sr substitution impact on the crystal structure and electrophysical properties of the phases on the base of BaNd2In2O7
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Y. A. Titov, N. N. Belyavina, M. S. Slobodyanik, O. I. Nakonechna, N. Yu. Strutynska, and R. N. Kuzmin
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General Chemical Engineering ,Materials Chemistry ,General Chemistry ,Biochemistry ,Industrial and Manufacturing Engineering - Published
- 2022
6. Comparative analysis of random graph models
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Vladimir N. Kuzmin, Fedor L. Shuvaev, and Maxim V. Rozganov
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Computer Networks and Communications ,Computer Science Applications ,Information Systems - Published
- 2022
7. Mitochondrial Dysfunction: A Prelude to Neuropathogenesis of SARS-CoV-2
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Artem Pliss, Andrey N. Kuzmin, Paras N. Prasad, and Supriya D. Mahajan
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Letter ,Physiology ,SARS-CoV-2 ,Cognitive Neuroscience ,Brain ,COVID-19 ,ROS ,Cell Biology ,General Medicine ,Biochemistry ,mitochondria ,Humans ,Raman spectrometry ,Microglia ,skin and connective tissue diseases ,neuro-COVID - Abstract
The SARS-CoV-2 virus is notorious for its neuroinvasive capability, causing multiple neurological conditions. The neuropathology of SARS-CoV-2 is increasingly attributed to mitochondrial dysfunction of brain microglia cells. However, the changes in biochemical content of mitochondria that drive the progression of neuro-COVID remain poorly understood. Here we introduce a Raman microspectrometry approach that enables the molecular profiling of single cellular organelles to characterize the mitochondrial molecular makeup in the infected microglia cells. We found that microglia treated with either spike protein or heat-inactivated SARS-CoV-2 trigger a dramatic reduction in mtDNA content and an increase in phospholipid saturation levels. At the same time, no significant changes were detected in Golgi apparatus and in lipid droplets, the organelles that accommodate biogenesis and storage of lipids. We hypothesize that transformations in mitochondria are caused by increased synthesis of reactive oxygen species in these organelles. Our findings call for the development of mitochondria-targeted therapeutic approaches to limit neuropathology associated with SARS-CoV-2.
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- 2022
8. On the memory of Eugene N. Borza (1935-2021)
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Yuri N. Kuzmin
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- 2022
9. Characteristics that act in young people as psychological prerequisites to avoid psychological intimacy in relationships
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Vera V. Korshunova, Yulia G. Yudina, Tatyana V. Skutina, Dmitry N. Kuzmin, and Ekaterina V. Potapova
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General Medicine ,Psychology - Abstract
The article empirically substantiates the hypothesis about the severity of the characteristics of avoiding psychological intimacy in young people: low autonomy, self-doubt, the presence of an avoidant type of attachment, counter-dependence, the experienced lack of intimacy in relationships with significant adults in childhood and the needs for isolation and security in subjective perceptions of psychological intimacy. These characteristics were compared in two groups of boys and girls aged 20-25 years, the sample was 60 people. Methods were used: "Questionnaire of interpersonal dependence" (p. Girshfield, adapted by O.P. Makushina), the questionnaire "The experience of close relationships" by K. Brennan and R.K. Fraley, adapted by T.V. Kazantseva, the test for counter-dependence (B.K. Weinhold, D.B. Weinhold). The severity of closeness by significant adults in childhood, the peculiarities of subjective ideas about psychological closeness were revealed by the method of conversation and through the creation of a drawing "The image of the desired relationship". The results of the study showed that the differences between the groups are significant in all parameters stated in the hypothesis (p ≤ 0.01). Subjective ideas about intimacy differ in the severity of the needs to be the center of your world in a relationship; in community; in observing personal boundaries; (p ≤ 0.01); to feel safe in a relationship (p ≤ 0.05).
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- 2021
10. Development of Problem-Oriented Management and Decision-Making System and Optimization of Economic and Social Systems
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Andrey Valerievich Kurakov, Vladimir N. Kuzmin, Lyudmila V. Zubovа, Alexey Sergeevich Smirnov, and Eduard Viktorovich Korovin
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Human-Computer Interaction ,Information Systems and Management ,Process management ,Development (topology) ,Social system ,Computer science ,Library and Information Sciences ,Software - Abstract
The main goal of this study is to develop the theory of risk tolerance in task-oriented processes (using the example of enterprises engaged in research, development, and engineering), which is preceded by an analysis of scientific and methodological provisions for substantiating management decisions when developing promising space rocket technology under economic risks. The complexity of developing the theory of risk tolerance using the example of enterprises involved in the development of military and dual-use equipment lies in the multistructured evaluating system itself, justified by its multicomponent structure and large scale of topological complexity and logic of functioning in various modes and under different conditions, which leads to the need to divide it into a set of subsystems as moving substances in the process of task-oriented processes that have informational, methodological, and algorithmic commonality. That is accompanied by the decentralization of information processing in a structural parametric uncertainty. In this regard, in order to parameterize the uncertainty processes, the authors present a risk tolerance level assessment process diagram in task-oriented processes when developing military and dual-use equipment. Using the algorithm for determining the marginal cost of risk, marginal risk tolerance, and marginal risk level of an economic entity according to the method of L.V. Zubova, the work presents an approach of potentially dangerous risks (PDR) categorization of the financial and economic sphere and suggests ways to minimize risk, taking into account, if possible, risk rejection, determining the "cost of no action" in the face of uncertainty.
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- 2021
11. An approach to identifying threats of extracting confidential data from automated control systems based on internet technologies
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Artem B. Menisov and Vladimir N. Kuzmin
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Economics and Econometrics ,Automatic control ,business.industry ,Computer science ,Deep learning ,Information security ,Computer security ,computer.software_genre ,Management Information Systems ,Management of Technology and Innovation ,Confidentiality ,The Internet ,Artificial intelligence ,Business and International Management ,business ,computer ,Information Systems - Abstract
Together with ubiquitous, global digitalization, cybercrime is growing and developing rapidly. The state considers the creation of an environment conducive to information security to be a strategic goal for the development of the information society in Russia. However, the question of how the “state of protection of the individual, society and the state from internal and external information threats” should be achieved in accordance with the “Information Security” and the “Digital Economy of Russia 2024” programs remains open. The aim of this study is to increase the efficiency whereby automated control systems identify confidential data from html-pages to reduce the risk of using this data in the preparatory and initial stages of attacks on the infrastructure of government organizations. The article describes an approach that has been developed to identify confidential data based on the combination of several neural network technologies: a universal sentence encoder and a neural network recurrent architecture of bidirectional long-term short-term memory. The results of an assessment in comparison with modern means of natural language text processing (SpaCy) showed the merits and prospects of the practical application of the methodological approach.
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- 2021
12. Hot-band absorption of indocyanine green for advanced anti-stokes fluorescence bioimaging
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Xiaoxiao Fan, Zhe Feng, Jun Qian, Wen Liu, Yuhuang Zhang, Mubin He, Dingwei Xue, Andrey N. Kuzmin, Di Wu, Jie Liu, Paras N. Prasad, Zikang Ye, Jing Zhou, and Liang Zhu
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Materials science ,genetic structures ,Hot band ,Article ,law.invention ,chemistry.chemical_compound ,Computer Science::Hardware Architecture ,Nuclear magnetic resonance ,law ,natural sciences ,Applied optics. Photonics ,cardiovascular diseases ,Absorption (electromagnetic radiation) ,Imaging and sensing ,QC350-467 ,Velocimetry ,Optics. Light ,Laser ,Fluorescence ,Atomic and Molecular Physics, and Optics ,Photon upconversion ,eye diseases ,Electronic, Optical and Magnetic Materials ,respiratory tract diseases ,TA1501-1820 ,chemistry ,Continuous wave ,Biophotonics ,Indocyanine green - Abstract
Bright anti-Stokes fluorescence (ASF) in the first near-infrared spectral region (NIR-I, 800 nm–900 nm) under the excitation of a 915 nm continuous wave (CW) laser, is observed in Indocyanine Green (ICG), a dye approved by the Food and Drug Administration for clinical use. The dependence of fluorescence intensity on excitation light power and temperature, together with fluorescence lifetime measurement, establish this ASF to be originated from absorption from a thermally excited vibrational level (hot-band absorption), as shown in our experiments, which is stronger than the upconversion fluorescence from widely-used rare-earth ion doped nanoparticles. To test the utility of this ASF NIR-I probe for advanced bioimaging, we successively apply it for biothermal sensing, cerebral blood vessel tomography and blood stream velocimetry. Moreover, in combination with L1057 nanoparticles, which absorb the ASF of ICG and emit beyond 1100 nm, these two probes generate multi-mode images in two fluorescent channels under the excitation of a single 915 nm CW laser. One channel is used to monitor two overlapping organs, urinary system & blood vessel of a live mouse, while the other shows urinary system only. Using in intraoperative real-time monitoring, such multi-mode imaging method can be beneficial for visual guiding in anatomy of the urinary system to avoid any accidental injury to the surrounding blood vessels during surgery., Hot-band absorption based anti-Stokes fluorescence of ICG for evaluating the thermal state of the tumor and multi-organ imaging.
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- 2021
13. THE MODELING OF VIBRATION PROPERTIES IN THE HYDROGENATED DIAMOND-LIKE NANOFLAKES
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G. Ivanchenko, A. Ten, M. Butenko, and N. Kuzmin
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In this paper, the vibrational spectrum of diamane [1] is calculated within the framework of Hamilton's formalism. The geometric model of the diamane is represented as a two-layer graphene, but each C-atom has an sp3 hybridization of external electronic orbitals. The carbon atoms of one of the graphene sublattices are covalently bound to the atoms of the second graphene layer, and the outer hydrogen atoms are covalently attached to the atoms of the second sublattice. A diamane unit cell contains two carbon atoms and one hydrogen atom. When constructing the model, the deformation of the graphene plane as a result of the hydrogen atoms addition to it and the change in the hybridization of the external electronic orbitals of carbon atoms from sp2 to sp3 were taken into account. The interaction between hydrogen atoms was not taken into account.
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- 2022
14. Growth and Spectroscopy of Yb:YMgB5O10 Crystal
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Konstantin N. Gorbachenya, Anatol S. Yasukevich, Andrey I. Lazarchuk, Victor E. Kisel, Nikolay V. Kuleshov, Elena A. Volkova, Victor V. Maltsev, Elizaveta V. Koporulina, Vasiliy O. Yapaskurt, Nikolai N. Kuzmin, Dmitry A. Ksenofontov, Diana D. Mitina, and Anna I. Jiliaeva
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Inorganic Chemistry ,ytterbium ,spectroscopy ,rare-earth pentaborate ,flux growth ,ATR-FTIR spectroscopy ,General Chemical Engineering ,General Materials Science ,Condensed Matter Physics - Abstract
A transparent Yb:YMgB5O10 single crystal with dimensions up to 25 × 23 × 25 mm and weight 10.337 g was grown using a high-temperature solution growth on dipped seeds technique with a K2Mo3O10 solvent. The Yb3+ concentration was calculated to be 4.7 at.% (NYb = 3.71 × 1020 atoms/cm3) with a distribution coefficient Kd of 0.59. The grown crystal was characterized by means of PXRD, TGA-DSC and ATR-FTIR techniques. The spectroscopic characteristics of the Yb:YMgB5O10 crystal were demonstrated. Absorption cross-section spectra were produced. The luminescence spectra of the Yb:YMgB5O10 crystal were measured in the spectral range of 950–1100 nm. The luminescence kinetics of the 2F5/2 energy level were investigated and the lifetime was determined.
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- 2022
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15. Comparative Analysis of Soft Biological Tissue Ablation Characteristics Obtained by Electromagnetic Radiation of HF and UHF Ranges
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Svetlana V. Belavskaya, Liliya I. Lisitsyna, Anton N. Kuzmin, and Ekaterina K. Vinskaya
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- 2022
16. Advances in Raman spectroscopy and imaging for biomedical research
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Soumik Siddhanta, Andrey N. Kuzmin, Artem Pliss, Alexander S. Baev, Sunil K. Khare, Pramit K. Chowdhury, Ashok K. Ganguli, and Paras N. Prasad
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Atomic and Molecular Physics, and Optics - Abstract
Starting with a historical account of evolution in Raman spectroscopy, in this review we provide details of the advancements that have pushed detection limits to single molecules and enabled non-invasive molecular characterization of distinct organelles to provide next-generation bioanalytical assays and ultrasensitive molecular and cellular diagnostics. Amidst a growing number of publications in recent years, there is an unmet need for a consolidated review that discusses salient aspects of Raman spectroscopy that are broadly applicable in biosensing ranging from fundamental biology to disease identification and staging, to drug screening and food and agriculture quality control. This review offers a discussion across this range of applications and focuses on the convergent use of Raman spectroscopy, coupling it to bioanalysis, agriculture, and food quality control, which can affect human life through biomedical research, drug discovery, and disease diagnostics. We also highlight how the potent combination of advanced spectroscopy and machine-learning algorithms can further advance Raman data analysis, leading to the emergence of an optical Omics discipline, coined “Ramanomics.” Finally, we present our perspectives on future needs and opportunities.
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- 2023
17. FEATURES OF ACCOUNTING FOR THE RISKS OF AGRICULTURE IN THE ASPECT OF THE IMPLEMENTATION OF ITS SCIENTIFIC AND TECHNOLOGICAL DEVELOPMENT
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Valeriy N. KUZMIN, Nikolay P. MISHUROV, Oleg A. MOTORIN, and Pavel A. PODYABLONSKY
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- 2021
18. IDH1 mutations induce organelle defects via dysregulated phospholipids
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Christel Herold-Mende, Tomohiro Yamasaki, Christina Burks, Rebecca Schmitt, Michael J. Kruhlak, Mark R. Gilbert, Tyrone Dowdy, Lumin Zhang, Elena-Raluca Nicoli, Sudipto Das, Andrey N. Kuzmin, Chunzhang Yang, Artem Pliss, Adrian Lita, Paras N. Prasad, Orieta Celiku, Natalia de Val, Victor Ruiz-Rodado, Mioara Larion, and Thorkell Andresson
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0301 basic medicine ,IDH1 ,Science ,Oligodendroglioma ,Golgi Apparatus ,General Physics and Astronomy ,Endoplasmic Reticulum ,medicine.disease_cause ,Models, Biological ,Article ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,symbols.namesake ,0302 clinical medicine ,Cell Line, Tumor ,Lipid biosynthesis ,Lipidomics ,Organelle ,medicine ,Humans ,Gene silencing ,Phospholipids ,030304 developmental biology ,Organelles ,0303 health sciences ,Gene knockdown ,Mutation ,Multidisciplinary ,Chemistry ,Endoplasmic reticulum ,Lipid metabolism ,General Chemistry ,Golgi apparatus ,Cancer metabolism ,Isocitrate Dehydrogenase ,3. Good health ,Cell biology ,Cytosol ,030104 developmental biology ,Isocitrate dehydrogenase ,Apoptosis ,030220 oncology & carcinogenesis ,symbols ,lipids (amino acids, peptides, and proteins) ,Glioblastoma ,Stearoyl-CoA Desaturase - Abstract
Infiltrating gliomas are devastating and incurable tumors. Amongst all gliomas, those harboring a mutation in isocitrate dehydrogenase 1 mutation (IDH1mut) acquire a different tumor biology and clinical manifestation from those that are IDH1WT. Understanding the unique metabolic profile reprogrammed by IDH1 mutation has the potential to identify new molecular targets for glioma therapy. Herein, we uncover increased monounsaturated fatty acids (MUFA) and their phospholipids in endoplasmic reticulum (ER), generated by IDH1 mutation, that are responsible for Golgi and ER dilation. We demonstrate a direct link between the IDH1 mutation and this organelle morphology via D-2HG-induced stearyl-CoA desaturase (SCD) overexpression, the rate-limiting enzyme in MUFA biosynthesis. Inhibition of IDH1 mutation or SCD silencing restores ER and Golgi morphology, while D-2HG and oleic acid induces morphological defects in these organelles. Moreover, addition of oleic acid, which tilts the balance towards elevated levels of MUFA, produces IDH1mut-specific cellular apoptosis. Collectively, these results suggest that IDH1mut-induced SCD overexpression can rearrange the distribution of lipids in the organelles of glioma cells, providing new insight into the link between lipid metabolism and organelle morphology in these cells, with potential and unique therapeutic implications., The understanding of altered lipid metabolism by isocitrate dehydrogenase 1 (IDH1) mutations in gliomas at a compartment-specific level is limited. Here, the authors use Raman spectroscopy to monitor organelle-specific metabolic changes and report that IDH1 mutations induce phospholipid imbalances which lead to ER and Golgi dilation.
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- 2021
19. Structural Specific Features of Solid Solutions NdxGd1 – xCr3(BO3)4
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Kirill N. Boldyrev, E. A. Dobretsova, and N. N. Kuzmin
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Range (particle radiation) ,Materials science ,Absorption spectroscopy ,Near-infrared spectroscopy ,Analytical chemistry ,Crystal structure ,Laser ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Ion ,law.invention ,law ,Absorption (chemistry) ,Solid solution - Abstract
Optical investigations of crystals of solid solutions NdxGd1 – xCr3(BO3)4, 0.01 ≤ x ≤ 1, have been performed. Absorption spectra in the range of wavenumbers 11 000–15 000 cm–1 recorded at cryogenic temperatures (16 K) reveal a significant effect of the concentration of Nd3+ ions in the structure on the absorption in the near infrared range of the spectrum due to f–f transitions in the Nd3+ ion. It has been found that, at a concentration of х > 0.6, two nonequivalent Nd3+ centers are observed in the absorption spectra, which is explained by the presence of two polytypic modifications.
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- 2021
20. Anniversary of Viktor Nikolaevich Parfenov
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Yuri N. Kuzmin and Aleksandr A. Sinitsyn
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- 2021
21. A Power Supply for a Gas-Discharge Laser Based on a Lithium–Polymer Battery
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V. I. Sen, V A Gurashvili, I. D. Djigailo, V. N. Kuzmin, V. S. Nemchinov, D. A. Kirilenko, A. A. Vaselenok, A. K. Kondratenko, N. G. Turkin, and A. E. Poltanov
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Battery (electricity) ,Materials science ,Gas laser ,law ,Lithium polymer battery ,Internal resistance ,Instrumentation ,Voltage converter ,Automotive engineering ,Voltage ,Electric discharge in gases ,law.invention ,Power (physics) - Abstract
The results of experimental studies are presented and the experience of operating the power supply of a continuous gas laser, which is based on a lithium–polymer storage battery without an intermediate voltage converter, is analyzed. The long-term (more than 4-year) operation of a high-voltage battery power supply as a component of a laser system with an open-circuit voltage of 7.76 kV, a load voltage of 6.1 kV, a load current of up to 250 A, a power higher than 1.5 MVA, and a stored energy of 550 MJ is demonstrated. The response time of the switch for disconnecting the load in the case of breakdowns in the discharge chamber did not exceed 120 μs. The results of measurements of the internal resistance of the batteries and its changes during operation are presented.
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- 2021
22. Mass media discourse as an innovative means of representing the image of China in the British media language
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Diana A. Smirnova, Dmitriy N. Kuzmin, and Nadezhda A. Kozhura
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business.industry ,Media studies ,Sociology ,business ,China ,Mass media ,Image (mathematics) - Abstract
Nowadays, mass-media discourse is a common object of study in various research works. This is connected with the fact that information and telecommunication technologies are developing at a fast pace. Mass media discourse is inseparable from society, that is, a large audience for whom information is transmitted in a simplified form.The media seeks to influence public consciousness through mass-media discourse, forming certain attitudes and values in the public mind. The aim of the study is to identify the main conceptual characteristics of China's image, as presented in the British mass media discourse. The research analyzes articles on political and economic issues about China published by the British media. By means of contextual, conceptual and semantic analysis the authors identify and describe such basic conceptual characteristics of China's image being formed in the British mass-media discourse, as China – a business partner of Great Britain, China – a threat to the global economy, China – a state with slowing down development. The first conceptual characteristic presents China as a state it is economically profitable to cooperate with. The second one, in turn, indicates that the state of its economy affects the situation in the world. As for the third characteristic, it describes China as a country with less progressive development. In addition, there is a semantic classification of the lexical units characterizing China, as well as a comparative analysis of the percentage of words and expressions used. These conceptual characteristics are expressed by such parts of speech as nounsadjectives, verbs and adverbs, as well as by verb phrases. The words and expressions used fully describe Great Britain, confirming the accuracy of the highlighted characteristics.
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- 2021
23. Fatigue of structural materials in corrosive environments
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D. A. Goncharova, G. V. Pachurin, A. N. Kuzmin, and A. A. Filippov
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Structural material ,Materials science ,Metallurgy - Abstract
The factors influencing the fatigue failure of metals and alloys are investigated. To increase the resource and reliability of products made of metals and alloys, taking into account their operation conditions and the presence of a corrosive environment, when justifying the selection of a structural material, it is proposed to take into account its deflection curve under cyclic loading. Keywords: structural material, corrosive environment, fatigue resistance, fatigue cracks, deflection curve, cyclic loading, durability. pachuringv@mail.ru
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- 2020
24. Collectivity at the prolate-oblate transition: The 21+ lifetime of 190W
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E. Şahin, V. Werner, A.K. Mistry, M. Rudigier, K. Nomura, J. Jolie, N. Pietralla, P.H. Regan, G. Ağgez, H.M. Albers, U. Ahmed, Ö. Aktaş, A. Algora, S. Alhomaidhi, C. Appleton, T. Arıcı, M. Armstrong, A. Banerjee, J. Benito, G. Benzoni, A. Blazhev, P. Boutachkov, A.M. Bruce, B. Cederwall, M.M.R. Chishti, M.L. Cortés, F. Crespi, B. Das, T. Davinson, T. Dickel, M. Doncel, A. Ertoprak, A. Esmaylzadeh, L.M. Fraile, E.R. Gamba, J. Gerl, M. Górska, J. Ha, E. Haettner, O. Hall, H. Heggen, C. Hornung, N. Hubbard, S. Jazrawi, P.R. John, C.E. Jones, V. Karayonchev, E. Kazantseva, R. Kern, L. Knafla, I. Kojouharov, P. Koseoglou, G. Kosir, D. Kostyleva, N. Kurz, N. Kuzminchuk, M. Llanos-Expósito, R. Lozeva, D. Mengoni, T.J. Mertzimekis, M. Mikolajczuk, A.I. Morales, I. Mukha, J.R. Murias, B.S. Nara-Singh, S.E.A. Orrigo, J. Pellumaj, S. Pelonis, S. Pietri, S. Pigliapoco, Zs. Podolyák, M. Polettini, K. Rezynkina, H.A. Rösch, H. Schaffner, Ch. Scheidenberger, L. Sexton, P.-A. Söderström, Y.K. Tanaka, J.J. Valiente-Dobón, P. Vasileiou, J. Vasiljević, J. Vesic, H. Weick, J. Wiederhold, A. Yaneva, G. Zhang, J. Zhao, and A. Zyriliou
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Nuclear structure ,γ-ray spectroscopy ,Isomer spectroscopy ,Shape phase transition ,DESPEC ,NUSTAR ,Physics ,QC1-999 - Abstract
The neutron-rich rare isotope 190W is discussed as a candidate for a prolate-oblate transitional nucleus with maximum γ-softness. The collectivity of this isotope is assessed for the first time by the measurement of the reduced E2 transition probability of its first 2+ state to the ground state. The experiment employed the FAst TIming Array (FATIMA), comprised of 36 LaBr3(Ce) scintillators, which was part of the DESPEC setup at GSI, Darmstadt. The 41+ and 21+ states of 190W were populated subsequently to the decay of its 127(12) μs isomeric Jπ=10− state. The mean lifetime of the 21+ state was determined to be τ=274(28) ps, which corresponds to a B(E2;21+→01+) value of 95(10) W.u. The results motivated a revision of previous calculations within an energy-density functional-based interacting boson model-2 approach, yielding E2 transition properties and spectroscopic quadrupole moments for tungsten isotopes. From comparison to theory, the new data suggest that 190W is at the transition from prolate to oblate structure along the W isotopic chain, which had previously been discussed as a nuclear shape-phase transition.
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- 2024
- Full Text
- View/download PDF
25. ΠΥΡΟΚΑΥΣΙΣ: CIVIC AND MILITARY ORGANIZATION OF THE MACEDONIAN SOCIETY IN THE HELLENISTIC EPOCH
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Yuri N. Kuzmin
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History ,Epoch (reference date) ,language ,Macedonian ,Ancient history ,language.human_language ,Military organization - Published
- 2020
26. An approach to identifying bots in social networks based on the special association of classifiers
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Vladimir N. Kuzmin, Artem B. Menisov, and Ivan Anatolevich Shastun
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Economics and Econometrics ,Social network ,business.industry ,Computer science ,Association (object-oriented programming) ,Variance (accounting) ,Machine learning ,computer.software_genre ,Management Information Systems ,Stock exchange ,Management of Technology and Innovation ,Classifier (linguistics) ,The Internet ,Artificial intelligence ,Business and International Management ,business ,Adaptation (computer science) ,computer ,Categorical variable ,Information Systems - Abstract
Currently the use of bots, i.e., auto-accounts in social networks which are managed with special programs but disguised as ordinary users, has serious consequences. For example, bots have been used to influence political elections, distort information on the Internet and manipulate prices on the stock exchange. Many research teams concerned with the detection of such accounts have made use of machine learning methods. However, the practical results of detecting social network bots indicate significant limitations because the methodological tools used have language limitation and ineffective criteria for detection. This article presents improved countermeasures in a methodological approach to develop a universal social network account classifier for minimizing the average risk of errors in bot detection. The application of an assembly of classifiers united by a data adaptation criterion and results from the variance of each model found the formation of a universal classifier for social network accounts. The main results obtained by the authors consist of the criteria system and the categorical (nominal) features transformation approach for the formation of the special ensemble of classifiers. In practice, use of the ensemble of classifiers allows us to increase the effectiveness of bot detection compared to other approaches.
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- 2020
27. Growth and Spectroscopic and Magnetic Properties of TbCr3(BO3)4 Crystals
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N. N. Kuzmin, A. N. Bludov, Kirill N. Boldyrev, N. I. Leonyuk, V. V. Maltsev, and E. A. Volkova
- Subjects
010302 applied physics ,Phase transition ,Materials science ,General Chemical Engineering ,Metals and Alloys ,Analytical chemistry ,Infrared spectroscopy ,chemistry.chemical_element ,Terbium ,02 engineering and technology ,Atmospheric temperature range ,021001 nanoscience & nanotechnology ,01 natural sciences ,law.invention ,Inorganic Chemistry ,Chromium ,chemistry ,law ,Phase (matter) ,0103 physical sciences ,Materials Chemistry ,Crystallization ,0210 nano-technology ,Monoclinic crystal system - Abstract
We have studied and optimized conditions for spontaneous flux growth of TbCr3(BO3)4 crystals. Phase relations in the pseudoternary system TbCr3(BO3)4–K2Mo3O10–B2O3 have been studied in the temperature range 900–1130°C and the single-phase terbium chromium borate crystallization field has been mapped out. It has been shown that increasing the TbCr3(BO3)4 content of the starting high-temperature solution leads to a rhombohedral-to-monoclinic phase transition. Using K2Mo3O10-based high-temperature solutions, we have grown single-phase TbCr3(BO3)4 single crystals or crystals in which the rhombohedral phase (sp. gr. R32) significantly prevails over the monoclinic phase (sp. gr. C2/c). The grown crystals have been characterized by X-ray diffraction techniques, IR spectroscopy, and magnetic measurements.
- Published
- 2020
28. Experience in supporting viticulture in the European Union
- Author
-
V. N. Kuzmin
- Subjects
0106 biological sciences ,Economy ,Political science ,media_common.cataloged_instance ,04 agricultural and veterinary sciences ,European union ,Viticulture ,0405 other agricultural sciences ,01 natural sciences ,040501 horticulture ,010606 plant biology & botany ,media_common - Abstract
In connection with the creation of the subprogram for the development of viticulture in the framework of the Federal scientific and technical program for the development of agriculture for 2017-2025 the analysis of foreign experience in supporting this sub-sector is relevant. The countries of the European Union (EU) are collectively the main producers, consumers and exporters of grape wine in the world. The goal of the EU viticulture support system is to bring the wine-growing and wine-making sector to structural change that are protected from a permanent market crisis. Each EU member-state has a budget set by the EU and can choose from the eight areas of support provided (promotion of wine products within the EU and in third-country markets – up to 50 % of regulated expenses; restructuring and rearrangement of wine yards – up to 50-75%; investment in tangible or intangible fixed assets, processing plants, wine infrastructure, marketing structures and tools for the production or sale of wine products – up to 40-75 %; innovation – supports material or non-material investments aimed at developing new products, procedures and technologies that improve the marketing and competitiveness of EU wine products – up to 50-75 % of regulated costs; distillation of by-products of wine in order to eliminate them and thus improve the quality of wines; “green” harvest-destruction of part or complete destruction of unripe grapes in a certain area-up to 50 % of the direct costs of destruction plus loss of income associated with destruction or disposal; mutual funds – for farmers who want to insure against market fluctuations; crop insurance), which must be applied within the framework of national programs to support agricultural industries for a period of five years. Goals, planned results, the range of organizations that can receive this support, the application procedure, eligibility criteria, subsidized and non-subsidized expenses, standard (normative) unit costs, the procedure for selecting applications, priority criteria and appropriate weighting, the timing of payment of subsidies, and advances are defined for each support area.
- Published
- 2020
29. Comparison of Large-Area Low-Energy Electron Accelerators Based on a High-Voltage Glow Discharge with Accelerators Based on Longitudinal Filaments
- Author
-
I. D. Djigailo, V. I. Sen, V. N. Kuzmin, V A Gurashvili, V. S. Nemchinov, V. Ya. Shvedyuk, S. L. Kosogorov, N. A. Uspensky, O. V. Komarov, and G. A. Baranov
- Subjects
010302 applied physics ,Glow discharge ,Materials science ,010308 nuclear & particles physics ,Particle accelerator ,Electron ,01 natural sciences ,Computational physics ,law.invention ,Low energy ,law ,0103 physical sciences ,Cathode ray ,Physics::Accelerator Physics ,Instrumentation ,FOIL method ,Beam (structure) ,Voltage - Abstract
—A wide-aperture low-energy electron accelerator based on a high-voltage glow discharge (HVGD) is considered in comparison with accelerators based on a number of longitudinal filaments. The basic design features and advantages of HVGD-based accelerators are presented. These studies showed that it is possible to obtain high values of the density of the electron beam current extracted from the foil (56 µA/cm2) and rather high values of the beam extraction efficiency (35%) in comparison with the previously attained results. The obtained characteristics are comparable with the parameters of the accelerators based on a number of longitudinal filaments. The ability of the accelerator to operate with HVGD is demonstrated both in continuous and pulse–periodic modes without a change in its design. Various ion–electron optical systems of HVGD accelerators have been studied and the advantages of slit-type systems are shown.
- Published
- 2020
30. Analysing the reading skill development in first grade pupils with psychological developmental delay
- Author
-
Valeriya N. Ostashkova and Dmitry N. Kuzmin
- Subjects
Psychiatry and Mental health ,Neuropsychology and Physiological Psychology ,Health Policy ,Reading (process) ,media_common.quotation_subject ,Mathematics education ,Psychology ,Skill development ,media_common - Abstract
The article presents a theoretical review of the reasons of disability to form the reading skills, and analyzes the results of the research into forming the reading skills in first grade pupils with psychological developmental delay at the end of the school year.
- Published
- 2020
31. ANALYSIS OF THE DEVELOPMENT TASKS OF THE FEDERAL SCIENTIFIC AND TECHNICAL PROGRAM FOR AGRICULTURAL DEVELOPMENT IN THE PRISM OF RISK-BASED APPROACHES
- Author
-
Valeriy N. KUZMIN, Nikolay P. MISHUROV, Oleg A. MOTORIN, and Pavel A. PODYABLONSKY
- Published
- 2020
32. Exceptional case of surgical treatment of huge inguinal hernia at the woman
- Author
-
V M Serko, A V Pastukhov, I A Solovyov, B B Bromberg, D V Cherkashin, T E Koshelev, D N Kuzmin, O V Balyura, and M V Vasilchenko
- Subjects
03 medical and health sciences ,Inguinal hernia ,medicine.medical_specialty ,0302 clinical medicine ,business.industry ,General surgery ,Medicine ,030211 gastroenterology & hepatology ,030204 cardiovascular system & hematology ,business ,medicine.disease ,Surgical treatment - Abstract
Despite significant progress in a health care system the started cases of huge inguinal hernias still meet. For successful treatment of such patients objective diagnostics, preoperative preparation, the choice of suitable tactics of surgery and treatment in the postoperative period is important. The clinical case of treatment by not reducible huge inguinal hernia at the patient of 73 years is presented in article. The patient showed complaints to presence of the big sizes of the hernia in the bottom of a stomach limiting movement of the patient and self-service reducing quality of life. For the first time hernial protrusion in inguinal area has appeared in 2008 which gradually increased in sizes. Since 2015 I have noted the intensive growth of hernia. I didn’t ask for medical care. To clinic it is brought by an ambulance crew with the diagnosis of The Restrained Inguinal Hernia direction. At the time of survey data for infringement weren’t. After comprehensive examination to the patient surgery in volume has been executed: a gryzhesecheniye on the right, plasticity across Liechtenstein. The postoperative period proceeded without complications. The patient is written out for the 13th days after operation. Extremely exceptional clinical case, the choice of adequate stage-by-stage preoperative inspection and treatment, optimum surgical tactics and postoperative kuration is shown. The chosen approach led to prevention of development of a cascade of the complications including a compartment syndrome, to elimination of cosmetic defect and restoration of quality of life.
- Published
- 2019
33. Utilization of High Frequency Electrical Signal for Biological Tissue Ablation
- Author
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Liliya I. Lisitsyna, Svetlana V. Belavskaya, Anton N. Kuzmin, Alexander A. Blokhin, Leonid G. Navrotsky, and Alexander N. Aleinik
- Published
- 2021
34. The magnetic properties of the LaCr3(BO3)4 crystal
- Author
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A. N. Bludov, V. V. Maltsev, S. L. Gnatchenko, I.V. Kolodiy, N. I. Leonyuk, N. N. Kuzmin, Yu. O. Savina, and Volodymyr Pashchenko
- Subjects
010302 applied physics ,Materials science ,Physics and Astronomy (miscellaneous) ,Magnetic moment ,Condensed matter physics ,Exchange interaction ,General Physics and Astronomy ,Atmospheric temperature range ,01 natural sciences ,Magnetic susceptibility ,Magnetic field ,Ferromagnetism ,0103 physical sciences ,Antiferromagnetism ,010306 general physics ,Néel temperature - Abstract
This article investigates the magnetic susceptibility, χ(T), of the two-phase (R32 + C2/c) crystal LaCr3(BO3)4 in the temperature range 2–300 K for two orientations of an external magnetic field. It has been established that both structural modifications of lanthanum chromium borate are ordered antiferromagnetically, with each of them having its own Neel temperature (6.5 and 8.5 K). It has been shown that at T > 60 K, the magnetic susceptibility is well described by the Curie–Weiss law with an effective magnetic moment of μeff = 3.86 μB/Cr3+ and a Curie–Weiss temperature of θ = –23 K. Within the Heisenberg spin chain model, taking into account the interchain exchange interaction, the authors have obtained the following exchange-interaction constants: an antiferromagnetic intrachain exchange (J/k = 4.8 K) and a ferromagnetic interchain exchange (J'/k = –0.28 K).
- Published
- 2020
35. Research of Optical Radiation Impact on Materials of Museum Exhibits and Requirements to Measurement Devices
- Author
-
Vladimir N. Kuzmin, Konstantin A. Tomsky, and Sergei S. Bayev
- Subjects
010309 optics ,Materials science ,business.industry ,021105 building & construction ,0103 physical sciences ,0211 other engineering and technologies ,Optoelectronics ,Optical radiation ,02 engineering and technology ,business ,01 natural sciences - Abstract
LED lighting creates capability of the best representation of museum exhibits and creation of additional light perception effects. It also allows us to use the results of light and colour measurements for adjustment of quantity and quality of lighting. Photometric devices may become permanent assistants in decoration of exhibitions and museum premises. Even more important are photometers for monitoring of acceptable level of illuminance and UV irradiance. With correct evaluation of adverse impact of LED lighting, there is an opportunity to significantly increase the permitted level of exhibits lighting, which is a permanent requirement by designers. The recommendations for standardisation of lighting are based on results of special studies performed with consideration of material light-resistance groups and properties of light sources. Such studies were performed by STE TKA, LLC, and GOSNIIRESTAVRATSII by request of the Ministry of Culture. The article describes major results of this study, which mainly aimed at specification of safe acceptable level of UV irradiation of materials with application of energy-saving fluorescent lamps as well as major characteristics of produced photometers. Similar studies and elaboration of recommendation are required also for LED light sources.
- Published
- 2019
36. The development of MTI-350TM mass spectrometer as an example of the creation of modern scientific and technological equipment
- Author
-
A. V. Saprygin, A. B. Maleev, D. N. Kuzmin, and L. N. Gall
- Subjects
Engineering ,business.industry ,Systems engineering ,Mass spectrometry ,business - Published
- 2019
37. King Demetrius II of Macedon: in the Shadow of Father and Son
- Author
-
Yuri N. Kuzmin
- Published
- 2019
38. A new double-cell polytype of samarium aluminum dimetaborate: Synthesis, crystal structure, and spectroscopic characterization
- Author
-
Alexander M. Antipin, Elena A. Volkova, Victor A. Rassulov, Nikolay N. Kuzmin, Elena Yu. Borovikova, Elena A. Latanova, and Elizaveta V. Koporulina
- Subjects
Mechanics of Materials ,Materials Chemistry ,General Materials Science - Published
- 2022
39. Laser-ablative synthesis of elemental Bi and Sm oxide nanoparticles for radiation nanomedicine
- Author
-
Anton A. Popov, Julia C. Bulmahn, Paras N. Prasad, G. V. Tikhonowski, Elena A. Popova-Kuznetsova, Andrei V. Kabashin, Irina N. Zavestovskaya, Vladimir Duflot, Andrey N. Kuzmin, Sergey M. Deyev, and S. M. Klimentov
- Subjects
Materials science ,Fabrication ,technology, industry, and agriculture ,Oxide ,Nanoparticle ,Nanotechnology ,Radiation ,Laser ,law.invention ,chemistry.chemical_compound ,Colloid ,chemistry ,law ,Nanomedicine ,Absorption (electromagnetic radiation) ,health care economics and organizations - Abstract
Radiation nanomedicine is an emerging field, which utilizes nanoformulations of high-Z elements and nuclear agents to improve therapeutic outcome and to reduce radiation dosage. This field lacks methods for controlled fabrication of biocompatible nanoformulations. Here, we present application of femtosecond laser ablation in liquids to fabricate stable colloidal solutions of ultrapure elemental Bi and isotope-enriched samarium oxide nanoparticles (NPs). The obtained spherical Bi and Sm oxide NPs have controllable size, while Bi NPs have remarkable absorption in the near-IR region. Exempt of any toxic by-products, laser-ablated Bi and Sm oxide NPs present a novel appealing nanoplatform for nuclear and radiotherapies.
- Published
- 2021
40. Fluorescence lifetime and quantitative microRaman spectral imaging to monitor molecular environment in single organelles for cellular diagnostics
- Author
-
Artem Pliss, Paras N. Prasad, and Andrey N. Kuzmin
- Subjects
medicine.medical_specialty ,symbols.namesake ,Fluorescence-lifetime imaging microscopy ,Nuclear magnetic resonance ,Materials science ,medicine ,symbols ,Raman spectroscopy ,Fluorescence ,Refractive index ,Spectral imaging - Published
- 2021
41. The shape of the Tz = +1 nucleus 94Pd and the role of proton-neutron interactions on the structure of its excited states
- Author
-
A. Yaneva, S. Jazrawi, M. Mikołajczuk, M. Górska, P.H. Regan, B. Das, H.M. Albers, S. Alhomaidhi, T. Arici, A. Banerjee, G. Benzoni, B. Cederwall, M.M.R. Chishti, D.D. Dao, T. Davinson, A. Gargano, J. Gerl, O. Hall, N. Hubbard, J. Jolie, I. Kojouharov, A.K. Mistry, F. Nowacki, M. Polettini, M. Rudigier, E. Şahin, H. Schaffner, A. Sharma, M. Armstrong, H.J. Wollersheim, P. Boutachkov, T. Dickel, E. Haettner, H. Heggen, Ch. Hornung, R. Knöbel, D. Kostyleva, N. Kurz, N. Kuzminchuk, I. Mukha, S. Pietri, W.R. Plass, Zs. Podolyák, C. Scheidenberger, Y.K. Tanaka, J. Vesic, H. Weick, U. Ahmed, Ö. Aktas, A. Algora, C. Appleton, J. Benito, A. Blazhev, A. Bracco, A.M. Bruce, M. Brunet, R. Canavan, A. Esmaylzadeh, L.M. Fraile, G. Häfner, K.P. Hucka, P.R. John, D. Kahl, V. Karayonchev, R. Kern, G. Košir, R. Lozeva, P. Napiralla, B.S. Nara Singh, R. Page, C.M. Petrache, N. Pietralla, J.-M. Régis, H. Rösch, P. Ruotsalainen, V. Sanchez-Temble, L. Sexton, R. Shearman, M. Si, V. Werner, J. Wiederhold, K. Wimmer, W. Witt, P. Woods, and G. Zimba
- Subjects
γ spectroscopy ,Fast-timing γ-ray coincidences ,pn interaction ,Isovector vs. isoscalar pairing ,Shell model ,Physics ,QC1-999 - Abstract
Reduced transition probabilities have been extracted between excited, yrast states in the N=Z+2 nucleus 94Pd. The transitions of interest were observed following decays of the Iπ=14+, Ex=2129-keV isomeric state, which was populated following the projectile fragmentation of a 124Xe primary beam at the GSI Helmholtzzentrum für Schwerionenforschung accelerator facility as part of FAIR Phase-0. Experimental information regarding the reduced E2 transition strengths for the decays of the yrast 8+ and 6+ states was determined following isomer-delayed Eγ1−Eγ2−△T2,1 coincidence method, using the LaBr3(Ce)-based FATIMA fast-timing coincidence gamma-ray array, which allowed direct determination of lifetimes of states in 94Pd using the Generalized Centroid Difference (GCD) method. The experimental value for the half-life of the yrast 8+ state of 755(106) ps results in a reduced transition probability of B(E2:8→+6+) = 205−25+34 e2fm4, which enables a precise verification of shell-model calculations for this unique system, lying directly between the N=Z line and the N=50 neutron shell closure. The determined B(E2) value provides an insight into the purity of (g9/2)n configurations in competition with admixtures from excitations between the (lower) N=3pf and (higher) N=4gds orbitals for the first time. The results indicate weak collectivity expected for near-zero quadrupole deformation and an increasing importance of the T=0 proton-neutron interaction at N=48.
- Published
- 2024
- Full Text
- View/download PDF
42. Synthesis and Laser-Related Spectroscopy of Er:Y2O3 Optical Ceramics as a Gain Medium for In-Band-Pumped 1.6 µm Lasers
- Author
-
Konstantin N. Gorbachenya, Anatol S. Yasukevich, Viktor E. Kisel, Kirill V. Lopukhin, Vladimir V. Balashov, Alexander V. Fedin, Miron N. Gerke, Elena A. Volkova, Vasiliy O. Yapaskurt, Nikolay N. Kuzmin, Dmitry A. Ksenofontov, Dmitry V. Korost, and Nikolay V. Kuleshov
- Subjects
Inorganic Chemistry ,General Chemical Engineering ,erbium ,optical ceramics ,sesquioxides ,laser-related spectroscopy ,structure ,General Materials Science ,Condensed Matter Physics - Abstract
In this paper, Er:Y2O3 optical ceramics were fabricated and details of the synthesis were presented. The spectral–luminescent properties of Er3+:Y2O3 optical ceramics were investigated. The absorption and emission cross-section spectra were determined. The luminescence kinetics at near 1.6 µm was single exponential and the lifetime of erbium 4I13/2 energy level was determined. In the frame of the conventional Judd–Ofelt theory, the emission properties of the energy levels of erbium 4I13/2 and 4I11/2 involved in laser operation at near 1.6 µm were calculated. The gain coefficient curves for typical values of the relative population of the upper laser level 4I13/2 were presented. The composition and structure were studied using the SEM, XRD, FTIR spectroscopy, and X-ray computer tomography techniques.
- Published
- 2022
43. Laser-Ablative Synthesis of Stable Aqueous Solutions of Elemental Bismuth Nanoparticles for Multimodal Theranostic Applications
- Author
-
G. V. Tikhonowski, Andrei V. Kabashin, Andrey N. Kuzmin, Anton A. Popov, Julia C. Bulmahn, S. M. Klimentov, Paras N. Prasad, University at Buffalo [SUNY] (SUNY Buffalo), State University of New York (SUNY), The National Research Nuclear University MEPhI (Moscow Engineering Physics Institute) [Moscow, Russia], Laboratoire Lasers, Plasmas et Procédés photoniques (LP3), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)
- Subjects
Materials science ,nanosheets ,General Chemical Engineering ,[SDV]Life Sciences [q-bio] ,chemistry.chemical_element ,Nanoparticle ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Article ,Bismuth ,Nanomaterials ,laser ablation in liquids ,lcsh:Chemistry ,symbols.namesake ,[SPI]Engineering Sciences [physics] ,bismuth (Bi) nanoparticles ,[CHIM]Chemical Sciences ,General Materials Science ,Fourier transform infrared spectroscopy ,ComputingMilieux_MISCELLANEOUS ,radiotherapy ,Aqueous solution ,Photothermal therapy ,021001 nanoscience & nanotechnology ,nanomedicine ,0104 chemical sciences ,3. Good health ,chemistry ,lcsh:QD1-999 ,symbols ,Nanomedicine ,0210 nano-technology ,Raman spectroscopy ,phototherapy - Abstract
Elemental bismuth (Bi) nanoparticles (NPs), with the high atomic density of the Bi nuclei, could serve as efficient targeted agents for cancer treatment, with applications such as contrast agents for computed tomography (CT) imaging, sensitizers for image-guided X-ray radiotherapy, and photothermal therapy. However, the synthesis of elemental Bi NPs suitable for biological applications is difficult using conventional chemical routes. Here, we explore the fabrication of ultrapure Bi-based nanomaterials by femtosecond laser ablation from a solid Bi target in ambient liquids and characterize them by a variety of techniques, including TEM, SEM, XRD, FTIR, Raman, and optical spectroscopy. We found that laser-ablative synthesis using an elemental Bi solid target leads to the formation of spherical Bi NPs having the mean size of 20&ndash, 50 nm and a low size-dispersion. The NPs prepared in water experience a fast (within a few minutes) conversion into 400&ndash, 500 nm flake-like nanosheets, composed of bismuth subcarbonates, (BiO)2CO3 and (BiO)4CO3(OH)2, while the NPs prepared in acetone demonstrate high elemental stability. We introduce a procedure to obtain a stable aqueous solution of elemental Bi NPs suitable for biological applications, based on the coating of Bi NPs prepared in acetone with Pluronic®, F68 and their subsequent transfer to water. We also show that the laser-synthesized elemental Bi NPs, due to their vanishing band gap, exhibit remarkable absorption in the infrared range, which can be used for the activation of photothermal therapy in the near IR-to-IR window with maximum optical transparency in biological media. Exempt of any toxic synthetic by-products, laser-ablated elemental Bi NPs present a novel appealing nanoplatform for combination image-guided photoradiotherapies.
- Published
- 2020
- Full Text
- View/download PDF
44. Features of magnetic and magnetoelectric properties, H-T phase diagram of GdCr3(BO3)4
- Author
-
M. U. Gutowska, A. Lynnyk, A. Szewczyk, V. Khrustalyov, V. V. Maltsev, N. N. Kuzmin, Yu. O. Savina, M. I. Kobets, S. L. Gnatchenko, V. Savitsky, A. N. Bludov, T. Zajarniuk, and N.I. Leonyuk
- Subjects
010302 applied physics ,Phase transition ,Materials science ,Condensed matter physics ,Field (physics) ,Strongly Correlated Electrons (cond-mat.str-el) ,Exchange interaction ,Magnetoelectric effect ,FOS: Physical sciences ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Electronic, Optical and Magnetic Materials ,Magnetic field ,Condensed Matter - Other Condensed Matter ,Magnetization ,Magnetic anisotropy ,Polarization density ,Condensed Matter - Strongly Correlated Electrons ,0103 physical sciences ,Condensed Matter::Strongly Correlated Electrons ,0210 nano-technology ,Other Condensed Matter (cond-mat.other) - Abstract
Comprehensive studies of magnetic properties of GdCr3(BO3)4 single crystal have been carried out. The integrals of intrachain and interchain exchange interactions in the chromium subsystem have been determined and the strength of Cr-Gd exchange interaction has been estimated. The values of the exchange field and the effective magnetic anisotropy field of GdCr3(BO3)4 have been estimated. The electric polarization along the a axis in the longitudinal geometry of the experiment has been detected. Correlations between the electric polarization and the magnetization of the studied compound have been found. The spin-reorientation phase transition in the magnetically ordered state has been found. This transition exists for the external magnetic field applied along any crystallographic direction and the transition field depends weakly on the direction of the field. The nature of the spin-reorientation phase transition has been discussed. Magnetic phase diagram has been constructed and spin configurations for the low-field and high-field phases have been proposed., 31 pages, 14 figures
- Published
- 2020
45. Organization of the Cage Management Separate Feeding of Parent Flock of High Productive Crosse Meat Chickens
- Author
-
T N Kuzmina and V N Kuzmin
- Abstract
The article analyzes technical solutions for separate feeding of chickens and roosters of a broiler parent flock with the cage keeping of a broiler breeder flock. It is noted that separate feeding of hens and roosters of meat crosses is adopted as a process standard in the industrial poultry. Failure to comply with this requirement decreases the percentage of fertilized eggs, increases mortality, culling of males and problems with replanting reserve roosters. Installation of a feed distribution system similar to that used for floor keeping eliminates the negative impact that feeding the poultry from the same feeders has. Its application in cage keeping requires changes in the design of the cage battery, which will take full advantage of the separate feeding of hens and males.
- Published
- 2022
46. Inside Cover: Cellular transformations in near‐infrared light‐induced apoptosis in cancer cells revealed by label‐free CARS imaging (J. Biophotonics 12/2019)
- Author
-
Paras N. Prasad, Svitlana M. Levchenko, Tymish Y. Ohulchanskyy, Junle Qu, Artem Pliss, and Andrey N. Kuzmin
- Subjects
Biophotonics ,Near infrared light ,Chemistry ,Apoptosis ,Cancer cell ,General Engineering ,Biophysics ,General Physics and Astronomy ,General Materials Science ,Cover (algebra) ,General Chemistry ,General Biochemistry, Genetics and Molecular Biology ,Label free - Published
- 2019
47. Modeling of Thermochemical Processes in the Biomass Particle Dipped into the Low-Temperature Binding Layer of the Catalyst
- Author
-
D. V. Klimov, S. N. Kuzmin, N. S. Muratova, and R. L. Isyomin
- Subjects
Materials science ,Chemical engineering ,Biomass particle ,Layer (electronics) ,Catalysis - Published
- 2018
48. A reflexotherapeutic device with five affecting factors; prospects of its further development and practical results obtained in this area
- Author
-
diagnostics, Omsk, Russian Federation, Svetlana V. Belavskaya, Natalia S. Chirkova, Alexander A. Blokhin, Leonid G. Navrotsky, Npp Verset, Novosibirsk, Russian Federation, Liliya I. Lisitsyna, Anton N. Kuzmin, and Yuri Veshkurtsev
- Subjects
Engineering ,Risk analysis (engineering) ,business.industry ,General Engineering ,business - Published
- 2017
49. Quasi-real-time range monitoring by in-beam PET: a case for 15O
- Author
-
S. Purushothaman, D. Kostyleva, P. Dendooven, E. Haettner, H. Geissel, C. Schuy, U. Weber, D. Boscolo, T. Dickel, C. Graeff, C. Hornung, E. Kazantseva, N. Kuzminchuk-Feuerstein, I. Mukha, S. Pietri, H. Roesch, Y. K. Tanaka, J. Zhao, M. Durante, K. Parodi, and C. Scheidenberger
- Subjects
Medicine ,Science - Abstract
Abstract A fast and reliable range monitoring method is required to take full advantage of the high linear energy transfer provided by therapeutic ion beams like carbon and oxygen while minimizing damage to healthy tissue due to range uncertainties. Quasi-real-time range monitoring using in-beam positron emission tomography (PET) with therapeutic beams of positron-emitters of carbon and oxygen is a promising approach. The number of implanted ions and the time required for an unambiguous range verification are decisive factors for choosing a candidate isotope. An experimental study was performed at the FRS fragment-separator of GSI Helmholtzzentrum für Schwerionenforschung GmbH, Germany, to investigate the evolution of positron annihilation activity profiles during the implantation of $$^{14}$$ 14 O and $$^{15}$$ 15 O ion beams in a PMMA phantom. The positron activity profile was imaged by a dual-panel version of a Siemens Biograph mCT PET scanner. Results from a similar experiment using ion beams of carbon positron-emitters $$^{11}$$ 11 C and $$^{10}$$ 10 C performed at the same experimental setup were used for comparison. Owing to their shorter half-lives, the number of implanted ions required for a precise positron annihilation activity peak determination is lower for $$^{10}$$ 10 C compared to $$^{11}$$ 11 C and likewise for $$^{14}$$ 14 O compared to $$^{15}$$ 15 O, but their lower production cross-sections make it difficult to produce them at therapeutically relevant intensities. With a similar production cross-section and a 10 times shorter half-life than $$^{11}$$ 11 C, $$^{15}$$ 15 O provides a faster conclusive positron annihilation activity peak position determination for a lower number of implanted ions compared to $$^{11}$$ 11 C. A figure of merit formulation was developed for the quantitative comparison of therapy-relevant positron-emitting beams in the context of quasi-real-time beam monitoring. In conclusion, this study demonstrates that among the positron emitters of carbon and oxygen, $$^{15}$$ 15 O is the most feasible candidate for quasi-real-time range monitoring by in-beam PET that can be produced at therapeutically relevant intensities. Additionally, this study demonstrated that the in-flight production and separation method can produce beams of therapeutic quality, in terms of purity, energy, and energy spread.
- Published
- 2023
- Full Text
- View/download PDF
50. Scientometric Methods for Identifying Scientific Leaders: New Mathematical Models
- Author
-
G. N. Kuzmin and Konstantin Fursov
- Subjects
Development (topology) ,Mathematical model ,Management science ,Computer science ,05 social sciences ,Multidimensional assessment ,0509 other social sciences ,050905 science studies ,050904 information & library sciences ,General Economics, Econometrics and Finance - Abstract
A new approach to the multidimensional assessment of research organizations is introduced. Based on the use of quantitative data, various types of research and development results are considered in the approach.
- Published
- 2017
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