1. Advanced maternal age and pregnancy outcomes: a multicountry assessment
- Author
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Ahmet Metin Gülmezoglu, Pisake Lumbiganon, João Paulo Souza, Rintaro Mori, Togoobaatar Ganchimeg, Joshua P. Vogel, Malinee Laopaiboon, and N. Intarut
- Subjects
Adult ,medicine.medical_specialty ,Asia ,Cross-sectional study ,Population ,Maternal-Child Health Centers ,Directive Counseling ,World Health Organization ,GRAVIDEZ (COMPLICAÇÕES) ,Middle East ,Pregnancy ,Risk Factors ,Maternal near miss ,Prevalence ,Medicine ,Humans ,Advanced maternal age ,education ,Perinatal Mortality ,education.field_of_study ,business.industry ,Obstetrics ,Infant, Newborn ,Pregnancy Outcome ,Obstetrics and Gynecology ,Middle Aged ,Stillbirth ,medicine.disease ,Standardized mortality ratio ,Cross-Sectional Studies ,Latin America ,Maternal Mortality ,Premature birth ,Health Care Surveys ,Africa ,Premature Birth ,Maternal death ,Female ,business ,Maternal Age - Abstract
OBJECTIVE: To assess the association between advanced maternal age (AMA) and adverse pregnancy outcomes. DESIGN: Secondary analysis of the facility-based cross-sectional data of the WHO Multicountry Survey on Maternal and Newborn Health. SETTINGS: A total of 359 health facilities in 29 countries in Africa Asia Latin America and the Middle East. SAMPLE: A total of 308 149 singleton pregnant women admitted to the participating health facilities. METHODS: We estimated the prevalence of pregnant women with advanced age (35 years or older). We calculated adjusted odds ratios of individual severe maternal and perinatal outcomes in these women compared with women aged 20-34 years using a multilevel multivariate logistic regression model accounting for clustering effects within countries and health facilities. The confounding factors included facility and individual characteristics as well as country (classified by maternal mortality ratio level). MAIN OUTCOME MEASURES: Severe maternal adverse outcomes including maternal near miss (MNM) maternal death (MD) and severe maternal outcome (SMO) and perinatal outcomes including preterm birth (
- Published
- 2014