42 results on '"N. Babazadeh"'
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2. Comparative analysis of void-containing and all-semiconductor 1.5 µm InP-based photonic crystal surface-emitting laser diodes
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Z. Bian, K. J. Rae, B. C. King, D. Kim, G. Li, S. Thoms, D. T. D. Childs, N. D. Gerrard, N. Babazadeh, P. Reynolds, J. Grant, A. F. McKenzie, J. R. Orchard, R. J. E. Taylor, and R. A. Hogg
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Physics ,QC1-999 - Abstract
This paper analyzes 2D photonic crystal surface-emitting laser diodes with void-containing and all-semiconductor structures by comparing their simulated mode distribution, band structure, and coupling coefficients. A photonic crystal design with a square lattice and circle atoms is considered.
- Published
- 2021
- Full Text
- View/download PDF
3. Antibiotic Resistance of Bacteria Causing Urinary Tract Infections in Children Hospitalized in Amirkola Children Hospital during 2010-2011
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R Barari Sawadkouhi, H Sorkhi, M Pournasrollah, A Bijani, N Babazadeh, and S Baleghi Damavandi
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Urinary Tract Infections ,Pediatrics ,Drug Resistance ,Microbial. ,Medicine ,Medicine (General) ,R5-920 - Abstract
BACKGROUND AND OBJECTIVE: After respiratory and gastrointestinal infections, urinary tract infection is the most common infectious disease in children that it causes renal scar and high blood pressure if timely treatment is not given. Knowledge of common pathogens and antibiotic resistance patterns for empirical treatment is necessary. The aim of this study was to evaluate the prevalence of common uropathogens and their antibiotic resistance patterns in children hospitalized in Amirkola children hospital.METHODS: This cross sectional study was performed retrospectively on the medical records of all children hospitalized in Amirkola children hospital with UTI diagnosis from March 2010 to 2011. Information about age, sex, underlying disease, previous illness history, uropathogens and its antimicrobial resistance was recorded.FINDINGS: Escherichia coli was the most frequently isolated pathogens (89%), and then klebsiella (3.1%) and pseudomonas aeruginosa (3.1%) were more common. Antibiotic susceptibility testing of isolated pathogens showed maximum resistance to ampicillin (88%) and cotrimoxazole (63%) and the least resistance to nitrofurantoin (9%) and amikacin (11%). The frequency of multidrug-resistant pathogens was 56.4%.CONCLUSION: The results of the study showed that E. coli is the most common germ that causes urinary tract infection and drug resistance to ampicillin and cotrimoxazole is the greatest.
- Published
- 2013
4. DYNAMICS OF BRAIN ENZYMES ACTIVITY IN RAT EXPOSED TO HYPOXIA
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A. M. Rashidova, S. N. Babazadeh, V. V. Mammedkhanova, and E. Sh. Abiyeva
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chemistry.chemical_classification ,Enzyme ,Chemistry ,lcsh:Biotechnology ,lcsh:TP248.13-248.65 ,enzymes of energy metabolism ,medicine ,Hypoxia (medical) ,medicine.symptom ,Cell biology - Abstract
The aim of the work was to study the dynamics of lactate dehydrogenase (LDH; EC 1.1.1.27), aconitase (AH; EC 4.2.1.3), NAD-dependent malate dehydrogenase (MDH; EC 1.1.1.37), succinate dehydrogenase (SDH; EC 1.3.99.1) activity in homogenates and sub-fractions of brain structures of rat prenatally endured hypoxia at the organogenesis stage (on 11–15 days of development) and their role in the formation of compensatory — adaptive mechanisms in brain in postnatal ontogenesis. It was revealed that increasing of lactate dehydrogenase and malate dehydrogenase activity (P < 0.001; P < 0.01, correspondently) in the brain structures of the rats prevented metabolic disturbances in the regulation mechanisms of biosynthetic and bioenergetics processes in the brain. It was shown that prenatal hypoxia upregulates aconitase activity in postnatal development and this process, probably, had a reversible character (P < 0.01), the highest indices of succinate dehydrogenase activity were noticed in the hypothalamus and cerebellum of 30-day-old rat as compared to the other structures (P
- Published
- 2019
5. Comparative analysis of void-containing and all-semiconductor 1.5 µm InP-based photonic crystal surface-emitting laser diodes
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Guangrui Li, Ben C. King, P. Reynolds, Dae Hyun Kim, J. Grant, Richard J. E. Taylor, Richard A. Hogg, Stephen Thoms, Katherine Rae, David T. D. Childs, Jonathan R. Orchard, Adam F. McKenzie, Neil D. Gerrard, Zijun Bian, and N. Babazadeh
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010302 applied physics ,Coupling ,Void (astronomy) ,Materials science ,business.industry ,Physics ,QC1-999 ,General Physics and Astronomy ,Physics::Optics ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,Square lattice ,law.invention ,Semiconductor ,law ,0103 physical sciences ,Optoelectronics ,0210 nano-technology ,business ,Electronic band structure ,Photonic crystal ,Diode - Abstract
This paper analyzes 2D photonic crystal surface-emitting laser diodes with void-containing and all-semiconductor structures by comparing their simulated mode distribution, band structure, and coupling coefficients. A photonic crystal design with a square lattice and circle atoms is considered.
- Published
- 2021
6. Proposal for Common Active 1.3- <tex-math notation='LaTeX'>$\mu$ </tex-math> m Quantum Dot Electroabsorption Modulated DFB Laser
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Mitsuru Sugawara, Richard A. Hogg, Ben J. Stevens, N. Babazadeh, Keizo Takemasa, Soroush A. Sobhani, Kenichi Nishi, and David T. D. Childs
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Physics ,Distributed feedback laser ,Absorption spectroscopy ,business.industry ,Physics::Optics ,02 engineering and technology ,Laser ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,law.invention ,020210 optoelectronics & photonics ,Quantum dot laser ,Quantum dot ,law ,0202 electrical engineering, electronic engineering, information engineering ,Chirp ,Optoelectronics ,Electrical and Electronic Engineering ,Absorption (electromagnetic radiation) ,business ,Intensity modulation - Abstract
Opportunities for the monolithic integration of a novel common quantum dot (QD)-active electroabsorption modulated laser are explored. An electric-field and temperature-dependent spectroscopic study of optical absorption and gain are presented in the state-of-the-art 1.3- $\mu \text{m}$ In(Ga)As/GaAs QD active material. The unique gain/absorption spectral shape, attributed to the QD’s density of states, allows for a number of possible modulation schemes dependent upon the selected laser wavelength detuning from the gain peak. Intensity modulation and change in absorption, leading to negative chirp operation, are demonstrated via absorption spectroscopy and gain measurement of eight-layer-stack QD-active material. Such a device would be able to provide positive or negative chirp dependent upon modulation scheme and gain/Bragg wavelength detuning.
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- 2019
7. 1.5 {\mu}m Epitaxially Regrown Photonic Crystal Surface Emitting Laser Diode
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Ben C. King, Richard J. E. Taylor, David T. D. Childs, Adam F. McKenzie, Richard A. Hogg, Guangrui Li, N. Babazadeh, Stephen Thoms, Jonathan R. Orchard, Katherine Rae, Donald A. MacLaren, Zijun Bian, and Neil D. Gerrard
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Materials science ,Laser diode ,business.industry ,Physics::Instrumentation and Detectors ,Physics::Optics ,Physics - Applied Physics ,Epitaxy ,Laser ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Semiconductor laser theory ,law.invention ,chemistry.chemical_compound ,Condensed Matter::Materials Science ,chemistry ,law ,Condensed Matter::Superconductivity ,Indium phosphide ,Optoelectronics ,Electrical and Electronic Engineering ,Photonics ,business ,Lasing threshold ,Photonic crystal ,Physics - Optics - Abstract
We present an InP-based epitaxially regrown photonic crystal surface emitting laser diode, lasing in quasi- CW conditions at 1523nm., Comment: 4 pages, 5 figures, journal submission for review
- Published
- 2020
8. Properties of laterally coupled photonic crystal surface-emitting laser two-dimensional arrays (Conference Presentation)
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Dae Hyun Kim, Adam F. McKenzie, Jonathan R. Orchard, David T. D. Childs, Richard J. E. Taylor, Neil D. Gerrard, Aleksandr Boldin, Richard A. Hogg, N. Babazadeh, Pavlo Ivanov, and Ben C. King
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Materials science ,Laser diode ,business.industry ,Physics::Optics ,Near and far field ,Laser ,law.invention ,Injection locking ,Wavelength ,law ,Optoelectronics ,Laser power scaling ,business ,Beam divergence ,Photonic crystal - Abstract
Photonic crystal surface emitting lasers (PCSELs) are a new class of laser diode, offering control over emission (wavelength, polarisation, beam shape) through photonic crystal design, as well as power scalability and low beam divergence. We present developments in 2D arrays of large scale (~150x150um) PCSELs, coherently coupled by 1mm long, 100 μm wide waveguides that can be electrically driven into loss or gain. By studying the spectral and current-power characteristics, we show coherent power scaling between multiple devices. We discuss injection locking between devices achieved through controllable 2D in-plane feedback and its effect on the near and far field emissions.
- Published
- 2020
9. Quantum dot-based optically pumped VCSELs with high-contrast periodic gratings
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N. Babazadeh, Ian D. Henning, P.K. Patil, Benjamin R. Cemlyn, Jon Heffernan, Tibor Fordos, R. J. Airey, Michael J. Adams, and Edmund Clarke
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High contrast ,Materials science ,Fabrication ,business.industry ,Size reduction ,Physics::Optics ,02 engineering and technology ,01 natural sciences ,010309 optics ,020210 optoelectronics & photonics ,Quantum dot ,0103 physical sciences ,0202 electrical engineering, electronic engineering, information engineering ,Spectroscopic ellipsometry ,Optoelectronics ,business - Abstract
We present our recent results on quantum dot-based VCSELs for O-band telecoms applications. The incorporation of Sirich SiN $_{x} /$SiO 2 distributed Bragg mirrors, which have been studied by spectroscopic ellipsometry, as well as using high-contrast SiN $_{x}1\mathrm {D}$ gratings will lead to a significant size reduction desirable for the fabrication.
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- 2019
10. Mode Control in Photonic Crystal Surface Emitting Lasers Through External Reflection
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Pavlo Ivanov, Benjamin J. Stevens, Gary Terrnent, Richard J. E. Taylor, Richard A. Hogg, David T. D. Childs, Bret Harrison, Guangrui Li, Jayanta Sarma, Timothy S. Roberts, and N. Babazadeh
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Distributed feedback laser ,Materials science ,business.industry ,Photonic integrated circuit ,Physics::Optics ,02 engineering and technology ,Laser ,Atomic and Molecular Physics, and Optics ,law.invention ,020210 optoelectronics & photonics ,Semiconductor ,Optics ,law ,0202 electrical engineering, electronic engineering, information engineering ,Reflection (physics) ,Continuous wave ,Optoelectronics ,Electrical and Electronic Engineering ,business ,Tunable laser ,Photonic crystal - Abstract
In this paper, we show the effect of lateral external\ud optical feedback on an all semiconductor photonic crystal surface\ud emitting laser (PCSEL). Initially, a PCSEL is grown and fabricated\ud with a square lattice of triangles, the device is shown to\ud operate electrically driven at room temperature under continuous\ud wave condition. We investigate, theoretically and experimentally,\ud the effect of lateral feedback on the performance of photonic crystal\ud lasers. Demonstrating a reduction in mode competition and\ud a modification to spatial mode distribution, opening routes to all\ud electronic beam shaping and divergence control.
- Published
- 2017
11. Unsteady heat transfer from a reservoir fluid by employing metal foam tube, helically tube and straight tube: A comparative experimental study
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M. Ashouri, Mohammad Mohsen Shahmardan, Ali Tamayol, Mohsen Nazari, and N. Babazadeh Baie
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Materials science ,Heat transfer enhancement ,Energy Engineering and Power Technology ,Thermodynamics ,02 engineering and technology ,Metal foam ,021001 nanoscience & nanotechnology ,Concentric tube heat exchanger ,Industrial and Manufacturing Engineering ,Nanofluid ,020401 chemical engineering ,Heat flux ,Heat transfer ,Tube (fluid conveyance) ,0204 chemical engineering ,Composite material ,0210 nano-technology ,Shell and tube heat exchanger - Abstract
The main purpose of this study is to experimentally investigate the transient heat transfer from a fluid stored inside a closed reservoir. Different cooling methods, i.e. the use of metal foam embedded tube, helical tube, and a straight tube, are used and compared for heat transfer from the fluid reservoir. CuO/water nanofluid in various volume fractions in the range of 0–0.2 (w/v) are also employed as cooling fluid. The experimental data shows a heat transfer enhancement of 42% and 45% for helical tube and metal foam tube respectively, as compare with the straight tube by using 0.2% (w/v) Cuo/water nanofluid. The experiments indicate that combination of the two presenting methods (metal foam/helical shape and nanofluids) has a significant capability to enhance the heat transfer rate. Finally, two correlations between Rayleigh number and non-dimensional heat flux are presented for the straight and porous tubes.
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- 2017
12. PECULIARITY OF CHANGES OF FORMATION TEMPERATURE WITHIN THE ABSHERON-PRIBALKHAN UPLIFT ZONE IN CONNECTION WITH THE PROCESSES OF OIL AND GAS GENERATION
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G. H. Ismayilova, A. N. Babazadeh, and A. A. Feyzullayev
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chemistry.chemical_classification ,Maturity (geology) ,geography ,Series (stratigraphy) ,geography.geographical_feature_category ,business.industry ,Process Chemistry and Technology ,Earth science ,Fossil fuel ,Geochemistry ,Window (geology) ,Geology ,Fault (geology) ,Structural basin ,Geotechnical Engineering and Engineering Geology ,Industrial and Manufacturing Engineering ,Oil generation ,chemistry ,Organic matter ,business - Abstract
The article presents the results of the analysis of the hydrocarbon potential (KH) of the Lower Pliocene sediments (Productive series (PS) in the Azerbaijan sector and Red colored series in the Turkmenistan (RS)) and the temperature conditions for its realization within the Absheron-Pribalkhan uplift zone. The analysis is based both on the study of the regularities of changes of temperature in the space, and on the directly evaluation of maturity of organic matter (HC) in the rock. As a result of the studies carried out, the low hydrocarbon potential of the Lower Pliocene sediments (PS-RS) and the epigenetic nature of the main hydrocarbon resources of the South Caspian Basin are confirmed. Two temperature zones are distinguished within the Absheron-Pribalkhan zone, the boundary between which passes along the supposed deep break fault between the structures of Neft-Dashlary and Gunashly. In accordance with the revealed zonality in the NW of the part of the zone, the upper threshold for the beginning of oil generation is timed to a depth of approximately 2.8 km and in SE it is submerged to a depth of approximately 4.5 km. On the whole, the organic matter of the Lower-Pliocene rocks within the Absheron-Pribalkhan zone, in the considered depth interval, is characterized by low maturity and is below the "oil window".
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- 2017
13. MCV Measurement of Abnormal Red Blood Cells Using Adaptive Neuro-Fuzzy System with Image Processing
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Saeed Setayeshi, P. Salehian, Hossein Arabalibeik, and N. Babazadeh Khameneh
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Abnormal red blood cells ,business.industry ,Computer science ,Pattern recognition ,Image processing ,Artificial intelligence ,business ,Adaptive neuro fuzzy system - Published
- 2016
14. Coherently Coupled Photonic-Crystal Surface-Emitting Laser Array
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Richard A. Hogg, Salam K. Khamas, Pavlo Ivanov, Guangrui Li, Jayanta Sarma, Alex J. Crombie, N. Babazadeh, Richard J. E. Taylor, Haiping Zhou, Ben J. Stevens, G. Ternent, David T. D. Childs, and Stephen Thoms
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Threshold current ,Materials science ,business.industry ,Physics::Optics ,Electroluminescence ,Laser array ,Laser ,Atomic and Molecular Physics, and Optics ,law.invention ,Optics ,law ,Optoelectronics ,Laser power scaling ,Electrical and Electronic Engineering ,business ,Photonic crystal ,Coherence (physics) - Abstract
The realization of a 1 × 2 coherently coupled photonic crystal surface emitting laser array is reported. New routes to power scaling are discussed and the electronic control of coherence is demonstrated.
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- 2015
15. Incorporating structural analysis in a quantum dot Monte-Carlo model
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Wei Li, Richard A. Hogg, S.A. Sobhani, Ian M. Ross, M. Sugawara, Negin Peyvast, Keizo Takemasa, David T. D. Childs, K. Nishi, Iain Butler, N. Babazadeh, Smowton, Peter M., and Belyanin, Alexey A.
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Materials science ,Applied Mathematics ,Monte Carlo method ,Condensed Matter Physics ,Dark field microscopy ,Molecular physics ,Spectral line ,Electronic, Optical and Magnetic Materials ,Computer Science Applications ,Quantum dot ,Quantum Dots ,Scanning transmission electron microscopy ,Density of states ,High angle ,Spontaneous emission ,Electrical and Electronic Engineering ,HAADF STEM ,inhomogeneous broadening - Abstract
We simulate the shape of the density of states (DoS) of the quantum dot (QD) ensemble based upon size information provided by high angle annular dark field scanning transmission electron microscopy (HAADF STEM). We discuss how the capability to determined the QD DoS from micro-structural data allows a MonteCarlo model to be developed to accurately describe the QD gain and spontaneous emission spectra. The QD DoS shape is then studied, with recommendations made via the effect of removing, and enhancing this size inhomogeneity on various QD based devices is explored.
- Published
- 2018
16. Strain Balancing of Metal-Organic Vapour Phase Epitaxy InAs/GaAs Quantum Dot Lasers
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Ian Farrer, Ian Tooley, Timothy S. Roberts, N. Babazadeh, Benjamin J. Stevens, Nobuhiko Ozaki, Richard A. Hogg, David T. D. Childs, Edmund Clarke, Jonathan R. Orchard, and D. J. Mowbray
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Materials science ,business.industry ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Epitaxy ,Laser ,Atomic and Molecular Physics, and Optics ,law.invention ,Gallium arsenide ,chemistry.chemical_compound ,020210 optoelectronics & photonics ,chemistry ,Quantum dot laser ,Quantum dot ,law ,Phase (matter) ,0202 electrical engineering, electronic engineering, information engineering ,Optoelectronics ,Electrical and Electronic Engineering ,0210 nano-technology ,business ,Layer (electronics) ,Lasing threshold - Abstract
Incorporation of a GaAs0.8P0.2 layer allows strain balancing to be achieved in self-assembled InAs/GaAs quantum dots (QDs) grown by metal organic vapor phase epitaxy. Tuneable wavelength and high density are obtained through growth parameter optimization, with emission at 1.27 μm and QD layer density 3 × 10 10 cm–2. Strain balancing allows close vertical stacking (30 nm) of the QD layers, giving the potential for increased optical gain. Modeling and device characterization indicates minimal degradation in the optical and electrical characteristics unless the phosphorus percentage is increased above 20%. Laser structures are fabricated with a layer separation of 30 nm, demonstrating low temperature lasing with a threshold current density of 100 A/cm2 at 130 K without any facet coating.
- Published
- 2017
17. Mode control in photonic crystal surface emitting lasers (PCSELs) through in-plane feedback (Conference Presentation)
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Ben J. Stevens, Richard A. Hogg, Richard J. E. Taylor, Olesya Ignatova, Guangrui Li, Pavlo Ivanov, N. Babazadeh, and David T. D. Childs
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Materials science ,business.industry ,Optical power ,Laser ,law.invention ,Indium gallium phosphide ,Condensed Matter::Materials Science ,chemistry.chemical_compound ,chemistry ,law ,Cleave ,Optoelectronics ,business ,Lasing threshold ,Quantum well ,Photonic crystal ,Beam divergence - Abstract
All-semiconductor photonic crystal surface-emitting lasers (PCSELs) operating in CW mode at room temperature and coherently coupled arrays of these lasers are reviewed. These PCSELs are grown via MOVPE on GaAs substrates and include QW active elements and GaAs/InGaP photonic crystal (PC) layer situated above this active zone. Atoms of triangular shapes have been shown to increase optical power from the PCSEL but are also shown to result in a competition between lasing modes. Simulation shows that the energy splitting of lasing modes is smaller for triangular atoms, than for circles making high power single-mode devices difficult to achieve. In this work we experimentally investigate the effect of lateral optical feedback introduced by a facet cleave along one or two perpendicular PCSEL edges. This cleavage plane is misaligned to the PC resulting in a periodic variation of facet phase along the side of the device. Results confirm that a single cleave selects the lowest threshold 2D lasing mode, resulting in a ~20% reduction in threshold current and favours single-mode emission. The addition of a second cleave at right-angles to the first has no significant effect upon threshold current. The virgin device is shown to have a symmetric far-field (1 degree) whilst a single cleave produces a 1 degree divergence perpendicular to cleave and 5 degree parallel to cleave. The second orthogonal cleave results in the far field becoming symmetric again but with a divergence angle of 1 degree indicating that single-mode lasing is supported over a wider area.
- Published
- 2017
18. Photonic crystal surface emitting lasers — Coherent arrays and external feedback
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Richard J. E. Taylor, N. Babazadeh, Benjamin J. Stevens, Richard A. Hogg, Pavlo Ivanov, Olesya Ignatova, David T. D. Childs, Guangrui Li, Yoshiaki Nakano, and T. Tanemura
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Materials science ,business.industry ,Astrophysics::High Energy Astrophysical Phenomena ,Photonic integrated circuit ,Physics::Optics ,02 engineering and technology ,Laser ,Epitaxy ,law.invention ,020210 optoelectronics & photonics ,Optics ,law ,0202 electrical engineering, electronic engineering, information engineering ,Optoelectronics ,Physics::Atomic Physics ,business ,Photonic crystal ,Coherence (physics) - Abstract
Electronic control of coherence in 2D arrays of photonic crystal surface emitting lasers is discussed.
- Published
- 2016
19. GaAs-based self-aligned stripe superluminescent diodes processed normal to the cleaved facet
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Kristian M. Groom, N. Babazadeh, Richard A. Hogg, Benjamin J. Stevens, D. Lei, O. M. S. Ghazal, and David T. D. Childs
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Facet (geometry) ,Materials science ,business.industry ,020208 electrical & electronic engineering ,02 engineering and technology ,Superluminescent diode ,Gallium arsenide ,Amplitude modulation ,chemistry.chemical_compound ,Optics ,chemistry ,Modulation ,0202 electrical engineering, electronic engineering, information engineering ,Continuous wave ,Optoelectronics ,Laser beam quality ,business ,Diode - Abstract
We demonstrate GaAs-based superluminescent diodes (SLDs) incorporating a window-like back facet in a self-aligned stripe. SLDs are realised with low spectral modulation depth (SMD) at high power spectral density, without application of anti-reflection coatings. Such application of a window-like facet reduces effective facet reflectivity in a broadband manner. We demonstrate 30mW output power in a narrow bandwidth with only 5% SMD, outline the design criteria for high power and low SMD, and describe the deviation from a linear dependence of SMD on output power as a result of Joule heating in SLDs under continuous wave current injection. Furthermore, SLDs processed normal to the facet demonstrate output powers as high as 20mW, offering improvements in beam quality, ease of packaging and use of real estate. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
- Published
- 2016
20. Study of electro-absorption effects in 1300nm In(Ga)As/GaAs quantum dot materials
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Richard A. Hogg, M. Sugawara, Keizo Takemasa, N. Babazadeh, K. Nishi, S.A. Sobhani, David T. D. Childs, Benjamin J. Stevens, Witzigmann, Bernd, Osiński, Marek, and Arakawa, Yasuhiko
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Materials science ,Condensed matter physics ,business.industry ,Quantum point contact ,Quantum-confined Stark effect ,02 engineering and technology ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Avalanche breakdown ,Condensed Matter::Materials Science ,symbols.namesake ,020210 optoelectronics & photonics ,Stark effect ,Quantum dot ,Electro-absorption modulator ,0202 electrical engineering, electronic engineering, information engineering ,symbols ,Optoelectronics ,business ,Quantum well ,Molecular beam epitaxy - Abstract
We describe a study of electro-absorption effects in high quality 1300nm InAs/GaAs quantum dot (QD) material grown by molecular beam epitaxy. The photocurrent spectra as a function of electric field is investigated and the quantum confined Stark shift of the QD states is compared to reports for various quantum well (QW) systems (GaAs/AlGaAs, InGaAs/GaAs, InGaAsP/InP). We show that the rate of shift of the QD absorption peak is smaller than that of the reported QW systems (~0.1 meV/kVcm-1 c.f. 0.15-0.2 meV/kVcm- 1) and that the QD ground-state absorption is comparatively insensitive to the applied electric field. We observe a strong QD absorption peak at all biases up to avalanche breakdown, which is not observed in previous reports for these QW systems.
- Published
- 2016
21. The spectral resolution of high temperature GaAs photon counting soft X-ray photodiodes
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N. Babazadeh, Chee Hing Tan, A.M. Barnett, R.B. Gomes, D.J. Bassford, Jo Shien Ng, and John E. Lees
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Physics ,Nuclear and High Energy Physics ,business.industry ,X-ray ,Semiconductor device ,Atmospheric temperature range ,Photon counting ,Photodiode ,law.invention ,Full width at half maximum ,law ,Optoelectronics ,business ,Spectroscopy ,Instrumentation ,Diode - Abstract
Circular mesa GaAs p+–i–n+ diodes for photon counting soft X-ray spectroscopy have been fabricated and characterised over a temperature range of +80 to –30 °C. The spectroscopic performance of the diodes, as measured by the FWHM of the Mn Kα X-ray line from an 55Fe radioisotope, is reported. In addition, we compare the GaAs diodes with previously fabricated and characterised Al0.8Ga0.2As p+–i–n+ diodes of similar geometry.
- Published
- 2011
22. Size anisotropy inhomogeneity effects in state-of-the-art quantum dot lasers
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K. Nishi, Keizo Takemasa, David T. D. Childs, Ian M. Ross, S.A. Sobhani, Wei Li, Richard A. Hogg, N. Babazadeh, M. Sugawara, and Iain Butler
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Materials science ,Physics and Astronomy (miscellaneous) ,02 engineering and technology ,Laser ,Molecular physics ,Dark field microscopy ,law.invention ,Gallium arsenide ,chemistry.chemical_compound ,020210 optoelectronics & photonics ,chemistry ,Quantum dot laser ,Quantum dot ,law ,Scanning transmission electron microscopy ,0202 electrical engineering, electronic engineering, information engineering ,Density of states ,Anisotropy - Abstract
We describe a high angle annular dark field scanning transmission electron microscopy study of a self-assembled InAs-GaAs quantum dot (QD) laser sample providing insight into the micro-structure of the QD ensemble. A size distribution anisotropy of the QDs is observed in the two orthogonal (110) planes, and this structural information is used to develop a density of states model for the QD ensemble which is shown to be in strong agreement with a range of optical spectroscopic measurements. This link between the micro-structure and optical properties allows routes to QD device simulation. We go on to discuss how changes to the micro-structure would affect the density of states and hence laser performance.We describe a high angle annular dark field scanning transmission electron microscopy study of a self-assembled InAs-GaAs quantum dot (QD) laser sample providing insight into the micro-structure of the QD ensemble. A size distribution anisotropy of the QDs is observed in the two orthogonal (110) planes, and this structural information is used to develop a density of states model for the QD ensemble which is shown to be in strong agreement with a range of optical spectroscopic measurements. This link between the micro-structure and optical properties allows routes to QD device simulation. We go on to discuss how changes to the micro-structure would affect the density of states and hence laser performance.
- Published
- 2018
23. Radiation tolerant DC characteristics of InAs/GaAs quantum-dot diodes
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K. Nishi, N. Babazadeh, Yifei Mu, Richard A. Hogg, M. Sugawara, Keizo Takemasa, Sang Lam, and Cezhou Zhao
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γ radiation ,Materials science ,Semiconductor quantum dots ,business.industry ,Quantum dot ,Optoelectronics ,Irradiation ,Radiation ,business ,Gamma irradiation ,Voltage ,Diode - Abstract
Effects of 137Cs gamma irradiation on the DC electrical characteristics of InAs/GaAs quantum dots (QDs) mesa diodes are reported. The devices were irradiated with gamma-rays for different doses ranging from 100 rad to about 1 Mrad (GaAs). The QDs mesa diodes are found to be tolerant to γ radiation. No enhanced leakage current and shift in the turn-on voltage were observed in the InAs/GaAs QD devices after exposure to γ-radiation. When irradiated by γ-rays continuously, there seemed to be a small degradation trend in the forward-bias current after irradiating the mesa diode for about six hours.
- Published
- 2015
24. Robust electrical characteristics of multiple-layer InAs/GaAs quantum-dot diodes under gamma irradiation
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Cezhou Zhao, Keizo Takemasa, Richard A. Hogg, Yifei Mu, Sang Lam, M. Sugawara, N. Babazadeh, and K. Nishi
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Reliability (semiconductor) ,Optics ,Materials science ,business.industry ,Quantum dot ,Electrode ,Photodetector ,Optoelectronics ,Irradiation ,Radiation ,business ,Diode ,Ionizing radiation - Abstract
To conclude, the InAs/GaAs QD devices display radiation-tolerant DC characteristics despite high total dose of gamma radiation. No permanent ionising damage to the III–V compound semiconductor devices has been observed. The off-state leakage current is not worsened even when the device is continuously irradiated by gamma radiation. The results show great promise of InAs/GaAs QD structure for realization of IR photodetectors with low noise floor and high reliability in radiation environments.
- Published
- 2015
25. Electronic control of coherence in a two-dimensional array of photonic crystal surface emitting lasers
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Alex J. Crombie, Richard A. Hogg, Benjamin J. Stevens, Stephen Thoms, Pavlo Ivanov, Haiping Zhou, N. Babazadeh, Richard J. E. Taylor, G. Ternent, and David T. D. Childs
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Multidisciplinary ,Mutual coherence ,Computer science ,business.industry ,Beam steering ,Physics::Optics ,Laser ,Interference (wave propagation) ,Data science ,Article ,law.invention ,Semiconductor laser theory ,Semiconductor ,law ,Optoelectronics ,business ,Waveguide ,Photonic crystal ,Coherence (physics) - Abstract
We demonstrate a semiconductor PCSEL array that uniquely combines an in-plane waveguide structure with nano-scale patterned PCSEL elements. This novel geometry allows two-dimensional electronically controllable coherent coupling of remote vertically emitting lasers. Mutual coherence of the PCSEL elements is verified through the demonstration of a two-dimensional Young’s Slits experiment. In addition to allowing the all-electronic control of the interference pattern, this type of device offers new routes to power and brightness scaling in semiconductor lasers and opportunities for all-electronic beam steering.
- Published
- 2015
26. Optimisation of fundamental transverse mode output in electrically pumped vertical external cavity surface emitting lasers
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Richard A. Hogg, Pavlo Ivanov, David T. D. Childs, John Orchard, Xiao Jin, Benjamin J. Stevens, and N. Babazadeh
- Subjects
Materials science ,business.industry ,Substrate (electronics) ,Laser ,law.invention ,Transverse mode ,Optics ,law ,Trench ,Optoelectronics ,Current (fluid) ,business ,Driven element ,Layer (electronics) ,Intensity (heat transfer) - Abstract
In this work we report on the simulation of electrically pumped vertical external cavity surface emitting lasers (EP-VECSELs). We simulate an etched mesa structure (substrate emission) with the substrate acting as the current spreading layer. The effect of contact misalignment on the carrier distribution within the active element is explored and confirms the validity of the model in describing the carrier distribution. We go on to discuss the effects of the substrate thickness and trench depth on the intensity profile. Simulation results show that a thicker substrate and a trench partially etched into the substrate may improve the intensity profile in future devices.
- Published
- 2015
27. GaAs Based Superluminescent Diodes Employing Window Facets in a Self-Aligned Stripe
- Author
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Benjamin J. Stevens, N. Babazadeh, Richard A. Hogg, David T. D. Childs, and O.M.S. Ghazal. K.M. Groom
- Subjects
Materials science ,Optics ,business.industry ,Optoelectronics ,Window (computing) ,Superluminescent diode ,business ,Diode ,Semiconductor laser theory - Published
- 2014
28. Coherently Coupled Photonic Crystal Surface Emitting Lasers
- Author
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Salam K. Khamas, L. R. Shepherd, Benjamin J. Stevens, Stephen Thoms, Richard A. Hogg, Alex J. Crombie, Haiping Zhou, N. Babazadeh, David T. D. Childs, Kristian M. Groom, Jayanta Sarma, Richard J. E. Taylor, G. Ternent, and Pavlo Ivanov
- Subjects
Surface (mathematics) ,Optics ,Materials science ,business.industry ,law ,Photonic integrated circuit ,Optoelectronics ,Distributed Bragg reflector ,business ,Laser ,law.invention ,Photonic crystal - Published
- 2014
29. Development of broad spectral bandwidth hybrid QW/QD structures from 1000-1400 nm
- Author
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Z. Y. Zhang, Takeo Kageyama, Keizo Takemasa, Richard A. Hogg, Negin Peyvast, K. Zhou, Maxime Hugues, K. Nishi, Osamu Wada, N. Babazadeh, S. Chen, A. A. Khozim, David T. D. Childs, and M. Sugawara
- Subjects
Physics ,Optics ,business.industry ,Modulation ,Broad bandwidth ,Quantum dot laser ,Quantum dot ,Optoelectronics ,Spontaneous emission ,business ,Driven element ,Spectral line ,Quantum well - Abstract
We describe the development of hybrid quantum well (QW)/quantum dot (QD) active elements to achieve broad spectral bandwidth spontaneous emission and gain. We have previously reported that the placement of the QW within the active element is a critical factor in obtaining broad spectral bandwidth emission. We now present new designs to further broaden the spontaneous emission from hybrid structures by increasing the number of QD layers and dot density, and by using QDs with wider state-separation. Introducing chirped QD layers reduced the modulation in the spontaneous emission spectra, and by utilising self-heating effects and state-filling, a spontaneous emission with 3dB line-width of 350nm is obtained.
- Published
- 2014
30. Broad bandwidth emission from hybrid QW/QD structures
- Author
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K. Nishi, S. Chen, N. Babazadeh, Maxime Hugues, Z. Y. Zhang, Mitsuru Sugawara, Osamu Wada, David T. D. Childs, Keizo Takemasa, Richard A. Hogg, K. Zhou, Takeo Kageyama, and Negin Peyvast
- Subjects
Physics ,business.industry ,Quantum point contact ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Gallium arsenide ,Laser linewidth ,chemistry.chemical_compound ,chemistry ,Quantum dot ,Quantum dot laser ,Electro-absorption modulator ,Optoelectronics ,Spontaneous emission ,business ,Quantum well - Abstract
We previously demonstrated a hybrid quantum well/quantum dot structure to enhance the gain and spontaneous emission bandwidth of a quantum dot active region. We now present new designs to further broaden the spontaneous emission from hybrid QW/QD structure. Utilizing a high junction temperature, and chirped quantum dot layers with higher areal densities, increased layer number, and increased state separation a spontaneous emission FWHM of ~350nm is achieved.
- Published
- 2013
31. GaAs p-i-n diodes for room temperature soft X-ray photon counting
- Author
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John P. R. David, Peter Vines, Jo Shien Ng, N. Babazadeh, Chee Hing Tan, R.B. Gomes, and John E. Lees
- Subjects
Materials science ,Fabrication ,business.industry ,Detector ,Photon counting ,Gallium arsenide ,chemistry.chemical_compound ,chemistry ,Etching (microfabrication) ,Optoelectronics ,Metalorganic vapour phase epitaxy ,business ,Leakage (electronics) ,Diode - Abstract
A study of leakage currents and X-ray photon counting using GaAs p-i-n diodes is presented. Different fabrication techniques have been investigated, namely He implantation, partial wet etching and full wet etching. It was found that the partially etched diodes showed well-defined spectral peaks when exposed to a 55Fe radioisotope source and uniformly low leakage currents ideal for X-ray detector arrays.
- Published
- 2011
32. Development of AlGaAs avalanche diodes for soft X-ray photon counting
- Author
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David J. Bassford, Peter Vines, Chee Hing Tan, Jo Shien Ng, N. Babazadeh, Donna Boe, Robert D. McKeag, R.B. Gomes, John E. Lees, A.M. Barnett, and John P. R. David
- Subjects
Physics ,X-ray spectroscopy ,APDS ,Physics::Instrumentation and Detectors ,business.industry ,Wide-bandgap semiconductor ,Atmospheric temperature range ,Avalanche photodiode ,Photon counting ,Gallium arsenide ,law.invention ,chemistry.chemical_compound ,chemistry ,law ,Optoelectronics ,business ,Diode - Abstract
We report on the performance of avalanche photodiodes (APDs) based on the wide band gap material AlGaAs which have been developed for soft X-ray spectroscopy applications. A number of diode types with different layer thicknesses have been characterised. The temperature dependence of the avalanche multiplication process at soft X-ray energies in Al 0.8 Ga 0.2 As APDs was investigated at temperatures from +80 °C to −20 °C. X-ray spectra from a 55Fe radioactive source show these diodes can be used for spectroscopy with promising energy resolution (0.9–2.5keV) over a wide temperature range. The temperature dependence of the pure electron initiated multiplication factor (M e ) and the mixed carrier initiated avalanche multiplication factor (M mix ) were experimentally measured. The experimental results are compared with a spectroscopic Monte Carlo model for Al 0.8 Ga 0.2 As diodes from which the temperature dependence of the pure hole initiated multiplication factor (M h ) is determined.
- Published
- 2011
33. Charge control in InP/GaInP single quantum dots embedded in Schottky diodes
- Author
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Andrey B. Krysa, C J Elliott, Alexander I. Tartakovskii, N. Babazadeh, M. S. Skolnick, Isaac J. Luxmoore, Jorge Puebla, O. D. D. Couto, and E. A. Chekhovich
- Subjects
Photocurrent ,Physics ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed matter physics ,business.industry ,Exciton ,Schottky diode ,FOS: Physical sciences ,Condensed Matter Physics ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Electronic, Optical and Magnetic Materials ,Dipole ,Condensed Matter::Materials Science ,Polarizability ,Quantum dot ,Electro-absorption modulator ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,Optoelectronics ,business ,Biexciton - Abstract
We demonstrate control by applied electric field of the charge states in single self-assembled InP quantum dots placed in GaInP Schottky structures grown by metalorganic vapor phase epitaxy. This has been enabled by growth optimization leading to suppression of formation of large dots uncontrollably accumulating charge. Using bias- and polarization-dependent micro-photoluminescence, we identify the exciton multi-particle states and carry out a systematic study of the neutral exciton state dipole moment and polarizability. This analysis allows for the characterization of the exciton wavefunction properties at the single dot level for this type of quantum dots. Photocurrent measurements allow further characterization of exciton properties by electrical means, opening new possibilities for resonant excitation studies for such system., Comment: 7 pages, 4 figures
- Published
- 2011
- Full Text
- View/download PDF
34. Development of high temperature AlGaAs soft X-ray photon counting detectors
- Author
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Js S. Ng, Jpr P. R. David, Rb B. Gomes, D. Boe, Peter Vines, D.J. Bassford, Ch H. Tan, N. Babazadeh, Am M. Barnett, Rd D. McKeag, and J.E. Lees
- Subjects
Physics ,APDS ,Physics::Instrumentation and Detectors ,business.industry ,Monte Carlo method ,X-ray detector ,Photon energy ,Avalanche photodiode ,Photon counting ,law.invention ,Single-photon avalanche diode ,law ,Optoelectronics ,business ,Instrumentation ,Mathematical Physics ,Diode - Abstract
New types of detectors based on the wide band gap material AlGaAs have been developed for soft X-ray spectroscopy applications. We report on the spectroscopic performance of simple p-i-n diodes and avalanche photodiodes (APDs). A number of diode types with different layer thicknesses have also been characterised. X-ray spectra from 55Fe and 109Cd radioactive sources show these diodes can be used for spectroscopy with promising energy resolution (1.0–1.25 keV) over a -30 to +90 °C temperature range. The temperature dependence of the avalanche multiplication process at soft X-ray energies in Al0.8Ga0.2As APDs was also investigated at temperatures from -20 to +80 °C. The temperature dependence of the pure electron initiated multiplication factor (Me) and the mixed carrier initiated avalanche multiplication factor (Mmix) were extracted from the X-ray spectra. The experimental results are compared with a spectroscopic Monte Carlo model for Al0.8Ga0.2As diodes from which the temperature dependence of the pure hole initiated multiplication factor (Mh) is determined. Monte Carlo simulations for the avalanche gain of absorbed X-ray photons have also been developed to study the relationship between avalanche gain and energy resolution for semiconductor X-ray avalanche photodiodes. The model showed that the distribution of gains, which directly affects the energy resolution, depends on the number of injected electron-hole pairs (and hence the photon energy), the relationship between the two ionization coefficients, and the overall mean gain. Our model showed that the conventional notion of APD gains degrading energy resolution significantly is incomplete. We compare the Monte Carlo simulations with experimental data from a number of different Al0.8Ga0.2As diodes.
- Published
- 2011
35. A GaAs-based self-aligned stripe distributed feedback laser.
- Author
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H Lei, B J Stevens, P W Fry, N Babazadeh, G Ternent, D T Childs, and K M Groom
- Subjects
DISTRIBUTED feedback lasers ,DIFFRACTION gratings ,OPTOELECTRONICS ,OPTICAL fiber cladding ,OPTICAL gratings - Abstract
We demonstrate operation of a GaAs-based self-aligned stripe (SAS) distributed feedback (DFB) laser. In this structure, a first order GaInP/GaAs index-coupled DFB grating is built within the p-doped AlGaAs layer between the active region and the n-doped GaInP opto-electronic confinement layer of a SAS laser structure. In this process no Al-containing layers are exposed to atmosphere prior to overgrowth. The use of AlGaAs cladding affords the luxury of full flexibility in upper cladding design, which proved necessary due to limitations imposed by the grating infill and overgrowth with the GaInP current block layer. Resultant devices exhibit single-mode lasing with high side-mode-suppression of >40 dB over the temperature range 20 °C–70 °C. The experimentally determined optical profile and grating confinement correlate well with those simulated using Fimmwave. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
36. GaAs-based superluminescent diodes with window-like facet structure for low spectral modulation at high output powers.
- Author
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O M S Ghazal, D T Childs, B J Stevens, N Babazadeh, R A Hogg, and K M Groom
- Subjects
SUPERLUMINESCENT diodes ,SPECTRUM analysis ,SPECTRAL energy distribution ,BANDWIDTHS ,RESISTANCE heating - Abstract
We demonstrate a GaAs-based superluminescent diode (SLD) based on the incorporation of a window-like back facet into a self-aligned stripe structure in order to reduce the effective facet reflectivity. This allows the realisation of SLDs with low spectral modulation depth (SMD) at high power spectral density (PSD), without the application of anti-reflection coatings to either facet. This approach is therefore compatible with ultra-broadband gain active elements. We show that 30 mW output power can be attained in a narrow bandwidth, corresponding to 2.2 mW nm
−1 PSD with only 5% SMD, centred about 990 nm. We discuss the design criteria for high power and low SMD and the deviation from a linear dependence of SMD on output power, resulting from Joule heating in the self-aligned stripe. [ABSTRACT FROM AUTHOR]- Published
- 2016
- Full Text
- View/download PDF
37. Purcell-enhanced single photons at telecom wavelengths from a quantum dot in a photonic crystal cavity.
- Author
-
Phillips CL, Brash AJ, Godsland M, Martin NJ, Foster A, Tomlinson A, Dost R, Babazadeh N, Sala EM, Wilson L, Heffernan J, Skolnick MS, and Fox AM
- Abstract
Quantum dots are promising candidates for telecom single photon sources due to their tunable emission across the different low-loss telecommunications bands, making them compatible with existing fiber networks. Their suitability for integration into photonic structures allows for enhanced brightness through the Purcell effect, supporting efficient quantum communication technologies. Our work focuses on InAs/InP QDs created via droplet epitaxy MOVPE to operate within the telecoms C-band. We observe a short radiative lifetime of 340 ps, arising from a Purcell factor of 5, owing to integration of the QD within a low-mode-volume photonic crystal cavity. Through in-situ control of the sample temperature, we show both temperature tuning of the QD's emission wavelength and a preserved single photon emission purity at temperatures up to 25K. These findings suggest the viability of QD-based, cryogen-free C-band single photon sources, supporting applicability in quantum communication technologies., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
38. Four patients with a clinically significant radial artery anomaly.
- Author
-
Babazadeh N, Zielsdorf S, Williams L, Farlow E, Keen R, and Sheng N
- Abstract
The superficial radial artery is an anatomic variant in which the radial artery passes superficial to the tendons of the anatomic snuffbox. Cadaver studies have shown its incidence to be 0.5% to 1%. Four patients with this anatomic variation were encountered in our practice, and their clinical courses and anatomy are described. One patient presented with digital ischemia after catheter placement in the anomalous radial artery. Three patients with end-stage renal disease were found to have a superficial radial artery incidentally, and this was used for inflow in the creation of hemodialysis fistulas.
- Published
- 2019
- Full Text
- View/download PDF
39. Electronic control of coherence in a two-dimensional array of photonic crystal surface emitting lasers.
- Author
-
Taylor RJ, Childs DT, Ivanov P, Stevens BJ, Babazadeh N, Crombie AJ, Ternent G, Thoms S, Zhou H, and Hogg RA
- Abstract
We demonstrate a semiconductor PCSEL array that uniquely combines an in-plane waveguide structure with nano-scale patterned PCSEL elements. This novel geometry allows two-dimensional electronically controllable coherent coupling of remote vertically emitting lasers. Mutual coherence of the PCSEL elements is verified through the demonstration of a two-dimensional Young's Slits experiment. In addition to allowing the all-electronic control of the interference pattern, this type of device offers new routes to power and brightness scaling in semiconductor lasers, and opportunities for all-electronic beam steering.
- Published
- 2015
- Full Text
- View/download PDF
40. Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death.
- Author
-
Wang DB, Garden GA, Kinoshita C, Wyles C, Babazadeh N, Sopher B, Kinoshita Y, and Morrison RS
- Subjects
- Animals, Cell Death physiology, Cells, Cultured, Dynamins, Fluorescent Antibody Technique, GTP Phosphohydrolases genetics, Humans, Immunoblotting, Mice, Mice, Knockout, Microtubule-Associated Proteins genetics, Mitochondrial Proteins genetics, Neurons metabolism, Oxidative Stress physiology, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Transfection, Tumor Suppressor Protein p53 genetics, Tumor Suppressor Protein p53 metabolism, Ubiquitin-Protein Ligases genetics, DNA Damage physiology, GTP Phosphohydrolases biosynthesis, Microtubule-Associated Proteins biosynthesis, Mitochondria pathology, Mitochondrial Proteins biosynthesis, Neurons pathology, Ubiquitin-Protein Ligases biosynthesis
- Abstract
Maintaining proper mitochondrial length is essential for normal mitochondrial function in neurons. Mitochondrial fragmentation has been associated with neuronal cell death caused by a variety of experimental toxic stressors. Despite the fact that oxidative stress is a hallmark of neurodegenerative conditions and aging and the resulting activation of p53 is believed to contribute to the neuropathology, little is still known regarding changes in mitochondrial morphology in p53-dependent neuronal death. Therefore, we specifically addressed the relationship between genotoxic stress, p53 activation, and the regulation of mitochondrial morphology in neurons. In cultured postnatal mouse cortical neurons, treatment with the DNA-damaging agent camptothecin (CPT) resulted in elongated mitochondria, in contrast to fragmented mitochondria observed upon staurosporine and glutamate treatment. In fibroblasts, however, CPT resulted in fragmented mitochondria. CPT treatment in neurons suppressed expression of the mitochondrial fission protein Drp1 and the E3 ubiquitin ligase parkin. The presence of elongated mitochondria and the declines in Drp1 and parkin expression occurred before the commitment point for apoptosis. The CPT-induced changes in Drp1 and parkin were not observed in p53-deficient neurons, while p53 overexpression alone was sufficient to reduce the expression of the two proteins. Elevating Drp1 or parkin expression before CPT treatment enhanced neuronal viability and restored a normal pattern of mitochondrial morphology. The present findings demonstrate that genotoxic stress in neurons results in elongated mitochondria in contrast to fission induced by other forms of stress, and p53-dependent declines in Drp1 and parkin levels contribute to altered mitochondrial morphology and cell death.
- Published
- 2013
- Full Text
- View/download PDF
41. Oil body mobilization in sunflower seedlings is potentially regulated by thioredoxin h.
- Author
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Babazadeh N, Poursaadat M, Sadeghipour HR, and Colagar AH
- Subjects
- Ascorbic Acid pharmacology, Electrophoresis, Polyacrylamide Gel, Helianthus drug effects, Lipid Metabolism drug effects, Seedlings drug effects, Helianthus metabolism, Plant Oils metabolism, Seedlings metabolism, Thioredoxins metabolism
- Abstract
Thioredoxins are believed to mediate starch and protein mobilization in germinating cereals and dicotyledons. Nothing is known about redox regulation of lipid mobilization in plants. The possible redox regulation by thioredoxin h (Trx h) of a thiol-protease which degrades the oleosin coat of the oil body and its impacts on lipid mobilization was investigated in sunflower (Helianthus annuus L.) seedlings. An alkaline proteolytic activity stimulated by light was detected in seedlings. In vitro, the activity of this alkaline protease increased after reduction by NADPH-thiordoxin reductase system (NTS). The expression pattern of an alkaline 65 kDa thiol protease detected by gelatin SDS-PAGE technique, corresponded to the activity profile of the NTS-activated protease. The thiol-specific fuorochrome monobromobimane (mBBr) showed that a 65 kDa protein was also in a reduced state in vivo and becomes reduced in vitro by NTS. Except for 17-20 kDa oleosins, other oil body associated mBBr-labeled proteins were disappeared within three days following germination. Treatments of sunflower oil bodies by the NTS-activated alkaline protease made them more susceptible to maize lipase action. Ascorbate application enhanced lipid mobilization of seedlings. A model for seedling oil body mobilization was proposed according to which Trx h or other Trx isoforms, reductively activates an oleosin degrading thiol-protease and some oil body proteins, thus renders the organelle more susceptible to subsequent lipolytic actions. For the first time the potential role of Trx in the mobilization of lipid reserves in plants has been shown., (Copyright © 2012 Elsevier Masson SAS. All rights reserved.)
- Published
- 2012
- Full Text
- View/download PDF
42. Abnormal red blood cells detection using adaptive neuro-fuzzy system.
- Author
-
Babazadeh Khameneh N, Arabalibeik H, Salehian P, and Setayeshi S
- Subjects
- Humans, Image Processing, Computer-Assisted methods, Diagnosis, Computer-Assisted, Erythrocytes, Abnormal physiology, Fuzzy Logic, Microscopy, Neural Networks, Computer
- Abstract
Features like size, shape, and volume of red blood cells are important factors in diagnosing related blood disorders such as iron deficiency and anemia. This paper proposes a method to detect abnormality in red blood cells using cell microscopic images. Adaptive local thresholding and bounding box methods are used to extract inner and outer diameters of red cells. An adaptive network-based fuzzy inference system (ANFIS) is used to classify blood samples to normal and abnormal. Accuracy of the proposed method and area under ROC curve are 96.6% and 0.9950 respectively.
- Published
- 2012
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