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3 results on '"N. Aissaoui-Balanant"'

1. Differential Effect of Targeted Temperature Management Between 32 °C and 36 °C Following Cardiac Arrest According to Initial Severity of Illness

Author

Jean Baptiste Lascarrou, Florence Dumas, Wulfran Bougouin, Stephane Legriel, Nadia Aissaoui, Nicolas Deye, Frankie Beganton, Lionel Lamhaut, Daniel Jost, Antoine Vieillard-Baron, Graham Nichol, Eloi Marijon, Xavier Jouven, Alain Cariou, F. Adnet, J.M. Agostinucci, N. Aissaoui-Balanant, V. Algalarrondo, F. Alla, C. Alonso, W. Amara, D. Annane, C. Antoine, P. Aubry, E. Azoulay, F. Beganton, C. Billon, W. Bougouin, J. Boutet, C. Bruel, P. Bruneval, A. Cariou, P. Carli, E. Casalino, C. Cerf, A. Chaib, B. Cholley, Y. Cohen, A. Combes, J.M. Coulaud, D. Da Silva, V. Das, A. Demoule, I. Denjoy, N. Deye, J.L. Diehl, S. Dinanian, L. Domanski, D. Dreyfuss, J.L. Dubois-Rande, F. Dumas, J. Duranteau, J.P. Empana, F. Extramiana, J.Y. Fagon, M. Fartoukh, F. Fieux, E. Gandjbakhch, G. Geri, B. Guidet, F. Halimi, P. Henry, P. Jabre, L. Joseph, D. Jost, X. Jouven, N. Karam, J. Lacotte, K. Lahlou-Laforet, L. Lamhaut, A. Lanceleur, O. Langeron, T. Lavergne, E. Lecarpentier, A. Leenhardt, N. Lellouche, V. Lemiale, F. Lemoine, F. Linval, T. Loeb, B. Ludes, C.E. Luyt, N. Mansencal, N. Mansouri, E. Marijon, E. Maury, V. Maxime, B. Megarbane, A. Mekontso-Dessap, H. Mentec, J.P. Mira, X. Monnet, K. Narayanan, N. Ngoyi, M.C. Perier, O. Piot, P. Plaisance, B. Plaud, I. Plu, J.H. Raphalen, M. Raux, F. Revaux, J.D. Ricard, C. Richard, B. Riou, F. Roussin, F. Santoli, F. Schortgen, T. Sharshar, G. Sideris, C. Spaulding, J.L. Teboul, J.F. Timsit, J.P. Tourtier, P. Tuppin, C. Ursat, O. Varenne, A. Vieillard-Baron, S. Voicu, K. Wahbi, and V. Waldmann

Subjects
Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Critical Care and Intensive Care Medicine
Published
2023

2. Should We Perform an Immediate Coronary Angiogram in All Patients After Cardiac Arrest?

Author

Wulfran Bougouin, Florence Dumas, Nicole Karam, Carole Maupain, Eloi Marijon, Lionel Lamhaut, Daniel Jost, Guillaume Geri, Frankie Beganton, Olivier Varenne, Christian Spaulding, Xavier Jouven, Alain Cariou, F. Adnet, J.M. Agostinucci, N. Aissaoui-Balanant, J. Albuisson, V. Algalarrondo, F. Alla, D. Annane, C. Antoine, P. Aubry, E. Azoulay, F. Beganton, D. Benhamou, W. Bougouin, C. Bruel, A. Cariou, P. Carli, C. Cerf, A. Chaib, J. Chastre, Y. Cohen, A. Combes, C. Cornaglia, D. Da Silva, V. Das, A. Demoule, N. Deye, G. Dhonneur, J.L. Diehl, S. Dinanian, L. Domanski, D. Dreyfuss, D. Duboc, J.L. Dubois-Rande, O. Dubourg, F.X. Duchateau, F. Dumas, J.P. Empana, F. Extramiana, J.Y. Fagon, M. Fartoukh, C. Fenioux, F. Fieux, F. Fraisse, M. Gabbas, E. Gandjbakhch, B. Guidet, P. Henry, F. Hidden Lucet, P. Jabre, L. Jacob, L. Joseph, D. Jost, D. Journois, X. Jouven, N. Karam, H. Kassim, K. Lahlou-Laforet, L. Lamhaut, A. Lanceleur, O. Langeron, V. Lanoe, E. Lecarpentier, A. Leenhardt, N. Lellouche, V. Lemiale, F. Linval, T. Loeb, B. Ludes, A. Maltret, N. Mansouri, J. Mantz, E. Marijon, J. Marty, E. Maury, V. Maxime, A. Mekontso-Dessaps, J.P. Mira, X. Monnet, M.C. Perier, O. Piot, R. Pirraccchio, I. Plu, M. Raux, F. Revaux, J.D. Ricard, C. Richard, B. Riou, F. Roussin, F. Santoli, F. Schortgen, T. Sharshar, G. Sideris, C. Spaulding, J.L. Teboul, J.F. Timsit, J.P. Tourtier, P. Tuppin, C. Ursat, O. Varenne, A. Vieillard-Baron, S. Voicu, and K. Wahbi

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Basic life support, Percutaneous coronary intervention, 030208 emergency & critical care medicine, 030204 cardiovascular system & hematology, Return of spontaneous circulation, Coronary angiogram, Logistic regression, Sudden death, 03 medical and health sciences, 0302 clinical medicine, Epinephrine, Internal medicine, medicine, Cardiology, Hospital discharge, Cardiology and Cardiovascular Medicine, business, medicine.drug
Abstract

Objectives This study sought to assess the relationship between an immediate invasive strategy and survival after an out-of-hospital cardiac arrest (OHCA) of presumed cardiac cause, according to prognosis evaluated on hospital arrival. Background An immediate coronary angiogram (CAG) may be associated with better outcome after OHCA in neurologically preserved patients but could be futile in other cases. Methods From May 2011 to May 2015, we collected data for all patients admitted in hospital after OHCA in Paris and its suburbs (France). Risk of in-hospital death was retrospectively calculated using the validated Cardiac Arrest Hospital Prognosis score, which includes age, setting, initial rhythm, durations from collapse to basic life support and from basic life support to return of spontaneous circulation, pH, and epinephrine dose. Independent predictors of survival at discharge (including immediate CAG) were assessed in multivariate logistic regression in each of the 3 pre-defined subgroups of Cardiac Arrest Hospital Prognosis score: low risk ( 200 points) for in-hospital death. Results A total of 1,410 patients were included and overall survival rate at hospital discharge was 32%. Distribution in the low-, medium-, and high-risk Cardiac Arrest Hospital Prognosis subgroups was 667 (47%), 469 (33%), and 274 patients (20%), respectively. The rate of early CAG was 86%, 66%, and 47% in the low-, medium-, and high-risk subgroups, respectively (p Conclusions In cardiac arrest patients, our results suggest that investigations regarding early CAG after OHCA should focus on patients with preserved neurological status.

Published
2018

3. Impact of early low-calorie low-protein versus standard-calorie standard-protein feeding on outcomes of ventilated adults with shock: design and conduct of a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3).

Author

Reignier J, Le Gouge A, Lascarrou JB, Annane D, Argaud L, Hourmant Y, Asfar P, Badie J, Nay MA, Botoc NV, Brisard L, Bui HN, Chatellier D, Chauvelot L, Combes A, Cracco C, Darmon M, Das V, Debarre M, Delbove A, Devaquet J, Voicu S, Aissaoui-Balanant N, Dumont LM, Oziel J, Gontier O, Groyer S, Guidet B, Jaber S, Lambiotte F, Leroy C, Letocart P, Madeux B, Maizel J, Martinet O, Martino F, Mercier E, Mira JP, Nseir S, Picard W, Piton G, Plantefeve G, Quenot JP, Renault A, Guérin L, Richecoeur J, Rigaud JP, Schneider F, Silva D, Sirodot M, Souweine B, Reizine F, Tamion F, Terzi N, Thévenin D, Thiéry G, Thieulot-Rolin N, Timsit JF, Tinturier F, Tirot P, Vanderlinden T, Vinatier I, Vinsonneau C, Maugars D, and Giraudeau B

Subjects
Adult, Critical Illness, Humans, Respiration, Artificial, SARS-CoV-2, COVID-19, Diet, Protein-Restricted
Abstract

Introduction: International guidelines include early nutritional support (≤48 hour after admission), 20-25 kcal/kg/day, and 1.2-2 g/kg/day protein at the acute phase of critical illness. Recent data challenge the appropriateness of providing standard amounts of calories and protein during acute critical illness. Restricting calorie and protein intakes seemed beneficial, suggesting a role for metabolic pathways such as autophagy, a potential key mechanism in safeguarding cellular integrity, notably in the muscle, during critical illness. However, the optimal calorie and protein supply at the acute phase of severe critical illness remains unknown. NUTRIREA-3 will be the first trial to compare standard calorie and protein feeding complying with guidelines to low-calorie low-protein feeding. We hypothesised that nutritional support with calorie and protein restriction during acute critical illness decreased day 90 mortality and/or dependency on intensive care unit (ICU) management in mechanically ventilated patients receiving vasoactive amine therapy for shock, compared with standard calorie and protein targets., Methods and Analysis: NUTRIREA-3 is a randomised, controlled, multicentre, open-label trial comparing two parallel groups of patients receiving invasive mechanical ventilation and vasoactive amine therapy for shock and given early nutritional support according to one of two strategies: early calorie-protein restriction (6 kcal/kg/day-0.2-0.4 g/kg/day) or standard calorie-protein targets (25 kcal/kg/day, 1.0-1.3 g/kg/day) at the acute phase defined as the first 7 days in the ICU. We will include 3044 patients in 61 French ICUs. Two primary end-points will be evaluated: day 90 mortality and time to ICU discharge readiness. The trial will be considered positive if significant between-group differences are found for one or both alternative primary endpoints. Secondary outcomes include hospital-acquired infections and nutritional, clinical and functional outcomes., Ethics and Dissemination: The NUTRIREA-3 study has been approved by the appropriate ethics committee. Patients are included after informed consent. Results will be submitted for publication in peer-reviewed journals., Trial Registration Number: NCT03573739., Competing Interests: Competing interests: JR had travel and accommodation expenses to attend scientific meetings covered by Baxter and Fresenius., (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2021
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