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Your search keyword '"N V, Levitskaia"' showing total 6 results
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6 results on '"N V, Levitskaia"'

1. Cancer patient management during the COVID-19 pandemic Training module. Version 2 from 30.04.2020

Author

L. G. Babicheva, S. N. Nered, R. I. Kniazev, M. I. Volkova, N. F. Orel, A. K. Allakhverdiev, A. V. Kriukov, G. S. Tumian, A. V. Ignatova, I. V. Sagaidak, T. V. Kharitonova, R. R. Sarmanaeva, M. P. Baranova, N. V. Levitskaia, G. R. Abuzarova, I. V. Kolyadina, S. O. Podviaznikov, P. P. Arkhiri, A. Iu. Kashurnikov, I. G. Komarov, O. A. Malikhova, V. K. Liadov, D. A. Sychev, O. P. Trofimova, I. S. Stilidi, and I. V. Poddubnaya

Subjects
Cancer Research, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), business.industry, pandemic, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cancer, medicine.disease, coronavirus infection in cancer patients, Patient management, covid-19, Oncology, Pandemic, Medicine, Christian ministry, Medical emergency, business, RC254-282
Abstract

The training module was developed by the staff of the department under the leadership of the head. Department of Academician of RAS, Professor I.V. Poddubnoy and Rector of FSBEI DPO RMANPO of the Ministry of Health of Russia, Corr. RAS, Professor D.A. Sychev.

Published
2020
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2. [Carcinosarcomas of the uterus: molecular-genetic and morphological features]

Author

N V, Levitskaia, K M, Pozharisskiĭ, O A, Vostriukhina, L N, Alekseeva, M V, Nemtsova, I V, Matrosova, T V, Kharitonova, and I V, Poddubnaia

Subjects
Proto-Oncogene Proteins p21(ras), Carcinosarcoma, Uterine Neoplasms, PTEN Phosphohydrolase, Humans, Loss of Heterozygosity, Female, Exons, Tumor Suppressor Protein p53, Retrospective Studies
Abstract

13 cases of uterine carcinosarcomas have been studied by molecular-genetic method. The impairment of some genes (K-RAS gene in the first exon, TP53 in the 5th-9th exons, PTEN in the 5th and 8th exons) has been found out. The loss of heterozygosity of TP53 gene in epithelium and mesenchyme of the uterus has been detected. According to the estimation of impairment the studied tumors was divided into monoclonal and biclonal ones. This stratification could be use as prognostic criteria of uterine carcinosarcomas clinical presentation.

Published
2012

3. [Carcinosarcoma of the corpus uteri: potential of p53, PTEN and COX-2 expression for survival]

Author

N V, Levitskaia, K M, Pozharisskiĭ, L N, Alekseeva, T V, Kharitonova, I V, Matrosova, and I V, Poddubnaia

Subjects
Adult, PTEN Phosphohydrolase, Middle Aged, Prognosis, Immunohistochemistry, Survival Analysis, Gene Expression Regulation, Neoplastic, Carcinosarcoma, Cyclooxygenase 2, Predictive Value of Tests, Uterine Neoplasms, Biomarkers, Tumor, Humans, Female, Tumor Suppressor Protein p53, Aged
Abstract

Clinico-morphological and immunohistochemical examinations were carried out in 46 patients with carcinocarcinoma of the corpus uteri to evaluate p53, PTEN and cyclooxygenase-2 (COX-2) expression in mesenchymal and epithelial cells of tumor. p53 expression in the epithelium and that of COX-2 in both compartments appeared to be unfavorable prognosticators of survival while that of PTEN is a lesser one in significance.

Published
2011

4. [Investigation of biological features of uterine carcinosarcoma]

Author

N V, Levitskaia, K M, Pozharisskiĭ, L N, Alekseeva, T V, Kharitonova, L E, Rotobel'skaia, and I V, Poddubnaia

Subjects
Adult, Adolescent, PTEN Phosphohydrolase, Middle Aged, Immunohistochemistry, Survival Analysis, Disease-Free Survival, Young Adult, Carcinosarcoma, Cyclooxygenase 2, Uterine Neoplasms, Biomarkers, Tumor, Humans, Female, Tumor Suppressor Protein p53, Aged
Abstract

Results of clinico-morphological and immunohistochemical studies of 44 cases of carcinosarcoma of the uterus are presented in an attempt to provide pathogenetic rationale for prognosticators of the disease. Immunohistochemical reactions were used to evaluate the expression of genes and mediators p53 and PTEN and cyclooxigenase (COX-2) in cells of mesenchyme and epithelium of tumor to gauge the influence of either component on its biological behavior. All patients were divided into two groups depending on whether they revealed expression of p53, PTEN and cyclooxigenase or not. The end results--overall survival and complete remission duration--were compared in both groups. No dominance of either component of carcinosarcoma was established.

Published
2010

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