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Your search keyword '"N P, Vodop'ianov"' showing total 9 results
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9 results on '"N P, Vodop'ianov"'

1. Herpes zoster-induced neuralgia (neuropathy)

Author

M Iu Maksimova, N A Sineva, and N P Vodop'ianov

Subjects
herpes zoster, neuralgia (neuropathy), trigeminal neuralgia, ramsay hunt syndrome, neuromidine, Medicine
Abstract

Neuralgia (neuropathy) is the most common manifestation of herpes zoster (HZ). In spinal and cranial neuralgia, there are 3 types of pain: 1) spontaneous, persistent, burning pain; 2) intermittent sharp pain; 3) pain occurring with nonpainful stimulation. The skin exhibits areas of hypesthesia, anesthesia, and dysesthesia. Ophthalmic neuralgia (of the first branch of the trigeminal nerve) is encountered in 20% of HZ cases. HZ of the auricle and external auditory meatus concurrent with facial and vestibulocochlear neuropathy is diagnosed as Ramsay Hunt syndrome. Postherpetic neuralgia (neuropathy) is characterized by pain present for 3 months or more after the appearance of herpetic eruptions. Combined therapy involving the earlier use of antiviral agents, tricyclic antidepressants, analgesics, and neuromidine is the most effective option for HZ-induced neuralgia (neuropathy).

Published
2014

2. Burning mouth syndrome (glossalgia)

Author

M Iu Maksimova, N A Sineva, N P Vodop'ianov, and E T Suanova

Subjects
glossalgia, stomalgia, neyromidine., Medicine
Abstract

Burning mouth syndrome (glossalgia) is manifested by oral pin and tingling sensations, numbness and even burning and severe pains, more frequently in the tongue. Unpleasant sensations may involve the anterior two thirds of the tongue or be extended to the front part of the hard palate and the mucous membrane of the lower lip. This condition is characterized by "mirror" and "food dominant" symptoms, disordered salivation, dysgeusia, or psychological disorders. The disease shows a chronic course. Its etiology may be multifactorial. There are no universally accepted diagnostic criteria; the diagnosis of glossalgia is made to rule out all other causes. A thorough examination should be conducted to establish a differential diagnosis. Glossalgia occurs primarily in middle-aged and elderly people. Women get sick much more frequently than men of the same age. Glossalgia remains difficult to treat. Continuous symptomatic treatment and follow-up help relieve its symptoms.

Published
2014

3. Neyromidin in the treatment of Stage I hypertensive dyscirculatory encephalopathy

Author

M Iu Maksimova, F Okhtova, N A Sineva, and N P Vodop'ianov

Subjects
arterial hypertension, hypertensive dyscirculatory encephalopathy, neyromidin, Medicine
Abstract

AIM: To evaluate the efficacy and safety of neyromidin in the treatment of Stage I hypertensive dyscirculatory encephalopathy (HDE) and to analyze long-term treatment results/MATERIAL AND METHODS: Fifty-seven with Stage I dyscirculatory encephalopathy in the presence of grades 1-2 arterial hypertension were examined. Clinical, psychological, and electrophysiological studies were performed and the efficacy of neyromidin was evaluated using the SANDOS geriatric scale. Neyromidin as monotherapy was used as one tablet (20 mg) b.i.d. during a meal. The duration of course treatment was 3 months/RESULTS: Positive changes in the early manifestations of HDE were observed just on day 45 of therapy. The therapeutic effect of the drug manifested as a reduction in the degree of clinical symptoms. There were positive changes in attention, memory, kinetics, verbal associations, counting. The most noticeable improvement was seen in the values of memory and intellectual processes, suggesting higher working capacity, reduced fatigability, and eliminated sluggishness of intellectual processes. EEG displayed a higher amplitude level, a better response to rhythmic photostimulation, and a total power rise in α- and ϑ-ranges, which was indicative of the activated effect of neyromidin on the functional state of brain structures/CONCLUSION: Neyromidin (20 mg b.i.d. for 3 months) was shown to be effective and well tolerated. The drug reduced the magnitude of clinical manifestations and improved psychological functions and electrophysiological parameters.

Published
2013

4. [Neyromidin in ischemic stroke]

Author

M Iu, Maksimova, D Z, Korobkova, N A, Sineva, N P, Vodop'ianov, and V N, Mikhal'chenko

Subjects
Male, Dose-Response Relationship, Drug, Hemodynamics, Administration, Ophthalmic, Middle Aged, Injections, Intramuscular, Magnetic Resonance Imaging, Brain Ischemia, Electrocardiography, Treatment Outcome, Aminoquinolines, Humans, Female, Tomography, X-Ray Computed, Aged
Abstract

An aim of the study was to evaluate the therapeutic effect of neyromidin in patients with ischemic stroke. Forty patients with acute carotid artery stroke were enrolled into the study. The diagnosis was made on the basis of general clinical methods as well as the neurological examination, CT or MRI scans of the head, investigation of hemodynamic parameters, ECG, ultrasound dopplerography of major brain arteries. Neurological deficit was measured using the Scandinavian Scale. According to the TOAST classification, 14 (35%) of the patients suffered from large vessel disease, 16 (40%) patients were diagnosed with cardioembolic disease and 10 (25%) with the small vessel disease. Patients were randomized to the study and control groups (n=20 patients). All patients received standard treatment. Patients of the study group were treated with neyromidin. The study duration was 80 days. Clinical examinations were performed in the acute phase, on 21st and 80th days after stroke. Better recovery of neurological functions was identified in patients treated with neyromidin compared to control patients. No side-effects of neyromidin was found. Neyromidin is recommended for complex treatment of patients in the acute stage of ischemic stroke of carotid origin.

Published
2013

5. [Neuromidin in the restoration of motor functions after ischemic stroke]

Author

M Iu, Maksimova, V N, Mikhal'chenko, N A, Sineeva, O V, Glebova, and N P, Vodop'ianov

Subjects
Male, Treatment Outcome, Aminoquinolines, Humans, Female, Recovery of Function, Middle Aged, Motor Activity, Aged, Brain Ischemia, Follow-Up Studies
Abstract

The efficacy of neyromidin in the treatment of motor disturbances after ischemic stroke (IS) was studied. The study included 60 patients with left middle cerebral artery stroke. The diagnosis was made on the basis of general clinical methods as well as the neurological examination, computed tomography (CT) scan of the head, investigation of hemodinamic parameters, ECG, ultrasound dopplerography of main head arteries, biochemical blood tests. Patients were divided into two equal groups: patients in the acute phase of stroke (main group) and patients in the early rehabilitation phase (comparison group). The groups were matched for sex, age, clinical features of the disease. Neyromidin was administered for 60 days. After the completion of the treatment with neyromidin, an improvement of the neurological status as well as an enhancement of motor functions in patients with moderate and severe paresis of the leg were observed in 30 patients with acute ischemic stroke.

Published
2013

6. [Hormonal disorders in women with prosopalgia in osteochondrosis of the cervical spine and the possible means for their correction]

Author

N E, Kushlinskiĭ, V E, Grechko, N A, Ivanov, I I, Klimenko, N A, Sineva, N P, Vodop'ianov, and A, Khasan

Subjects
Adult, Postmenopause, Pituitary Hormones, Premenopause, Cervical Vertebrae, Humans, Female, Laser Therapy, Middle Aged, Trigeminal Neuralgia, Gonadal Steroid Hormones, Osteochondritis, Spondylitis
Abstract

Radioimmunoassay was employed to determine basal levels of LH, FSH, prolactin, total testosterone and 17 beta-estradiol in plasma from 52 pre- or postmenopausal women with prosopalgia consequent to cervical osteochondrosis. The measurements were made before and after laser treatment. Different from the control, basal levels of the hormones and the trends in their changes due to laser therapy depended on the patients' age and the disease stage.

Published
1994

8. [Local and general humoral immunity in patients with migraine, Horton's syndrome and autonomic pain]

Author

M N, Puzin, A V, Kulakov, K E, Balashov, M N, Sharov, and N P, Vodop'ianov

Subjects
Adult, Male, Migraine Disorders, Facial Neuralgia, Immunoglobulins, Cluster Headache, Middle Aged, Immunoglobulin A, Vascular Headaches, Immunoglobulin M, Hypergammaglobulinemia, Immunoglobulin A, Secretory, Humans, Female, Dysgammaglobulinemia, IgG Deficiency, Saliva, Ganglia, Autonomic
Abstract

Patients with migraines, Horton syndrome and autonomic pains were subjected to immunological investigation that revealed different degrees of local and general immunity disorders: increase in blood serum IfA and salival IgAc concentrations. These changes are believed to be capable of serving as diagnostic and prognostic indices.

Published
1989

9. [Nervous system pathology in uterine myomas]

Author

Iu S, Martynov and N P, Vodop'ianov

Subjects
Adult, Leg, Leiomyoma, Electromyography, Peripheral Nervous System Diseases, Genitalia, Female, Syndrome, Middle Aged, Spinal Cord Diseases, Forearm, Thigh, Cerebrovascular Circulation, Uterine Neoplasms, Humans, Neuralgia, Female, Plethysmography, Impedance, Spinal Nerve Roots
Abstract

Clinico-physiological examinations of 218 patients with uterine myoma were carried out using the methods of electromyography and rheopgraphy. The following syndromes were revealed: a myopathic and a radiculoalgic ones; the syndrome of the external dermal femoral and the femorogenital nerves. The pathogenesis of these syndromes consists in compression of the lumbar arteries and the minor pelvis ganglia by the enlarged uterus. On condition of timely treatment including surgical ablation of the myoma the prognosis of the neurological disturbances is, as a rule, favourable.

Published
1979

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