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Copyright of Turkiye Klinikleri Journal of Health Sciences / Türkiye Klinikleri Sağlık Bilimleri Dergisi is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: We present data of patients with relapsed/refractory T cell lymphomas treated with brentuximab vedotin (BV) in real-world practice. Material and Method: This study is an observational, multi-center, retrospective study. The data of patients (n=17) treated with BV alone from January 2014 until July 2020 in thirteen centers from Turkey were collected. Results: Bv was given as salvage chemotherapy to 17 patients with median age of 53. Nine (52.9%) patients had diagnosis of peripheral T cell lymphoma, not otherwise specified; 8 (47.1%) patients had anaplastic large T cell lymphoma. The median follow-up of the cohort was 20 months. Nine (52.9%) patients had complete response, 5 (29.5%) had partial response, 3 (17.6%) had progressive disease. The safety results aligned with the established profile of BV, included 2 pneumonia and 1 thrombocytopenia with grade 4. The median progression free survival of the cohort was 10 months. BV cycle and response to BV therapy were found to have an effect on the univariate analysis. Conclusion: In patients with relapsed/refractory T cell lymphomas, BV seems to have convincing antitumor activity with favorable safety profile. [ABSTRACT FROM AUTHOR]

Background: aim of this study was to investigate the long-term clinical, functional and oncologic outcomes of patients with aneurysmal bone cyst (ABC). It was also aimed to reveal the effect of treatment options on recurrence and complications. Materials and Methods: Patients who underwent surgical treatment and follow-up with the diagnosis of ACS between 2000 and January 2023 were included in the study. Data were collected retrospectively using the hospital database and patient follow- up files. Only patients with a histologically confirmed diagnosis of ABC and a minimum follow-up period of 12 months were included in the study. Data such as age, gender, side, bone location of the tumor, extremity localization, preferred surgical method (curettage+allograft, curettage+allograft, curettage+autograft, curettage+cement and resection), whether internal fixation was applied, follow-up period, presence of recurrence and date of recurrence were recorded. The last follow-up was performed with the MSTS (Musculoskeletal Tumor Society) scoring system in outpatient clinic controls. On the basis of these data, the clinical, radiological, functional and oncological outcomes of the patients, complication rates, presence of recurrence and factors affecting the occurrence of recurrence were retrospectively analyzed. Results: A total of 103 patients, 51 women and 52 men, were included in the study. The mean follow-up period was 30.94±4.43 months. Recurrence was seen in 24.3% (n=25) of the patients. The age of patients with recurrence was significantly higher than those without recurrence (p<0.001). There was a statistically significant correlation between recurrence and internal fixation (p=0.020). The MSTS scores of patients who underwent internal fixation during surgery were significantly higher than those of patients who did not undergo internal fixation (p<0.001). Conclusions: In conclusion, in line with the data obtained in our study, the choice of treatment for aneurysmal bone cysts depends on localization, size, pathological fracture risk, symptoms and surrounding tissues. We believe that more caution should be exercised in the surgical treatment of ACCs with fracture risk, lower extremity localizations, and patients with incomplete skeletal development. Prevention of recurrence and internal fixation in patients with fracture risk increase patient satisfaction and positively affect functional outcomes. [ABSTRACT FROM AUTHOR]

Copyright of Aydin Dental Journal is the property of Aydin Dental Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Amaç: Bu çalışmanın amacı sabit ortodontik tedavi görmüş hastaların tedavi sonrası pekiştirme aşamasının hasta perspektifinden değerlendirilmesidir. Gereç ve Yöntem: Bu araştırma Google formlar programı kullanılarak 20 tane anket sorusunu doldurmayı kabul eden 8-18 ve >18 yaş arasındaki 100 hasta üzerinde gerçekleştirilmiştir. Hastaların verdikleri cevaplar doğrultusunda hastaların ortodontik tedavi sonrasında nüks hakkında bakış açıları değerlendirilmiştir. Elde edilen veriler cinsiyet, yaş, eğitim durumu, tedavi şekli gibi kriterlere göre SPSS 21 paket programı aracılığı ile analiz edilmiştir. Değişkenler arasındaki ilişkiye/bağımlılığa ki-kare analizi ile bakılmıştır. Bulgular: Ortodontik tedavi sonrası dişlerinde bozulma olmadığını düşünen bireylerin %96’sında lingual retansiyon apareyi yapılmıştır. Retansiyon apareyi kırılan hastaların %83.3’ü dişlerinde orta şiddette bozulma olduğunu bildirmiştir (p

Copyright of Acta Odontologica Turcica is the property of Acta Odontologica Turcica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: This study aims to investigate the clinical characteristics of pediatric patients diagnosed with supraventricular tachycardia (SVT) and assess their shortterm prognosis. Materials and Methods: Data from 213 patients diagnosed with SVT between 2010 and 2015 at the Department of Pediatric Cardiology, Bursa Uludag University Faculty of Medicine, were retrospectively reviewed. Results: The ratio of male to female patients was 1: 1.25. Regarding treatment response and prognosis, the recurrence rate of SVT attacks was higher in males. The most common complaint at the time of diagnosis was palpitation. Furthermore, 17.8% of patients were diagnosed due to tachycardia detected during routine check-ups; almost all were under one year of age. In 56.3% of patients, the initial diagnosis was made at the pediatric emergency clinic. In acute treatment, 30% of patients were treated with vagal maneuvers; 61% had their attacks terminated, while 41% received drug therapy. Adenosine was the most used drug, and it successfully terminated attacks in 79% of patients receiving it. In the evaluation of patients' follow-ups after the initial attack, 56.3% of patients experienced recurrences, and 71% of second attacks occurred within the first three months. Prophylactic drug therapy was initiated in 94.4% of patients, with an average duration of 2.5±1.6 years. After treatment discontinuation, 75.4% of patients remained symptom-free, while 24.6% experienced SVT attacks again. Electrophysiological studies were performed in 16.9% of patients at another centers, and ablation was applied to 15.5%. Conclusion: Patients with SVT may be asymptomatic during infancy and vagal stimulation and adenosine response was quite good in acute treatment. Prophylactic medical treatment was effective in children whose weight is <15 kg and the recurrences were low after discontinuation especially in infants. [ABSTRACT FROM AUTHOR]

Objective To investigate the relationship between inflammatory markers routinely examined in blood tests and their ratios with the development of recurrence after urethral stricture treatment. Material and Method A total of 142 patients who underwent internal urethrotomy were included in the study. Data were retrospectively reviewed. Patient ages, comorbidity status, medical treatments used, habits, previous surgical procedures, pre- and post-procedural uroflowmetry values, stricture locations and lengths, and preoperative and postoperative urine and blood test results were recorded. Results The recurrence rate within the first year after internal urethrotomy was determined to be 25.4%. The mean recurrence period was 8.9±1.9 months, ranging from 1 to 12 months, with a median recurrence period of 6 months. When the etiological factors causing urethral stricture were examined, iatrogenic causes were observed to be the most common. There were statistically significant differences in lymphocyte count, platelet count, platelet-lymphocyte ratio, and red cell distribution width-platelet ratio between the group with recurrence and the group without recurrence (p<0.05). Conclusion Platelet-lymphocyte ratio and red cell distribution width-platelet ratio can be used to predict possible recurrences after internal urethrotomy. The main advantages of both parameters are their simplicity, cost-effectiveness, and easy accessibility for clinical use. [ABSTRACT FROM AUTHOR]

Copyright of Yeni Üroloji Dergisi is the property of Ali Ihsan Tasci and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Günümüzde lingual ortodonti, hastaların estetik beklentilerinin artmasıyla birlikte gerçekten görünmeyen tek tedavi seçeneği olarak popülerliğini oldukça arttırmıştır. Lingual ortodontik tedavi, labial ortodontik tedavi ile kıyaslandığında fark edilebilirliğinin daha az olmasının yanı sıra beyaz nokta lezyonlarının oluşma sıklığı daha düşüktür. Daha önce labial ortodontik tedavi görmüş ve tedavisi nüksetmiş erişkin kadın hastanın klinik muayenesinde; solda 1/3 ünite Angle sınıf II maloklüzyon, üst arkta hafif, alt arkta orta şiddette çapraşıklık ve artmış overjet tespit edilmiştir. Hastanın estetik beklentisinin yüksek olması, beyaz nokta lezyonları bulunması, tedavi sırasında tork kontrolünde büyük avantaj sağlaması ve sonuçlarının öngörülebilir olması sebebiyle kişiye özel üretilen lingual braketler, ark telleri (WIN, DW Lingual Systems, Bad Essen, Germany) ve sınıf II elastik kullanılarak ideal kapanış ilişkisine ulaşılmıştır. Lingual ortodontik tedavi tüm maloklüzyonların tedavisinde başarılı bir şekilde kullanılmasının yanında, daha önce labial ortodontik tedavi görmüş, estetik beklentisi ve kaygısı yüksek hastaların tedavisi için ideal bir seçenektir.

Aim: The incidence of thyroid cancer has increased dramatically in recent decades. Multifocality is considered a poor prognostic factor for papillary thyroid carcinoma (PTC). Patients with multifocal PTC (MPTC) are at high risk for local recurrence, as well as lymphatic and distal metastases. This study examined the features and outcomes of MPTC. Material and Methods: This retrospective study was conducted on 300 patients with PTC. Patients were classified into a multifocal group and a unifocal group. The pathological features of the PTC and the patients’ outcomes were analyzed and compared. Results: The multifocal group included 146 patients (48.7%), while the unifocal group included 154 patients (51.3%). The occurrence of multifocality was higher in females than in males (Odds ratio, OR: 2.37, 95% confidence interval, CI: 1.20-4.67, p=0.015). Tumor size of >1 cm in the multifocal group was larger than in the unifocal group (2.5 and 2.2 cm, respectively, p=0.021). Moreover, in multifocal group higher moderate risk of recurrence was detected than in the unifocal group (OR: 1.63, 95% CI: 1.01-2.60, p=0.044). At follow-up after treatment, MPTC patients had higher lymph node metastasis (OR: 2.89, 95% CI: 1.23-6.80, p=0.014). In addition, significantly higher thyroglobulin plasma levels (p=0.026) and disease recurrence (OR: 2.41, 95% CI: 1.05-5.52, p=0.037) were found in the multifocal group compared to the unifocal group. Conclusion: Patients with MPTC had a higher risk of disease recurrence, and multifocality was concluded to be an independent prognostic factor for overall disease recurrence.

Objective: Atrial fibrillation (AF) is the most common directly preventable cause of ischemic stroke. There is no dependable neurology-based data on the spectrum of stroke caused by AF in Türkiye. Within the scope of NöroTek-Türkiye (TR), hospital-based data on acute stroke patients with AF were collected to contribute to the creation of acute-stroke algorithms. Materials and Methods: On May 10, 2018 (World Stroke Awareness Day), 1,790 patients hospitalized at 87 neurology units in 30 health regions were prospectively evaluated. A total of 929 patients [859 acute ischemic stroke, 70 transient ischemic attack (TIA)] from this study were included in this analysis. Results: The rate of AF in patients hospitalized for ischemic stroke/TIA was 29.8%, of which 65% were known before stroke, 5% were paroxysmal, and 30% were diagnosed after hospital admission. The proportion of patients with AF who received "effective" treatment [international normalization ratio ≥2.0 warfarin or non-vitamin K antagonist oral anticoagulants (NOACs) at a guideline dose] was 25.3%, and, either no medication or only antiplatelet was used in 42.5% of the cases. The low dose rate was 50% in 42 patients who had a stroke while taking NOACs. Anticoagulant was prescribed to the patient at discharge at a rate of 94.6%; low molecular weight or unfractionated heparin was prescribed in 28.1%, warfarin in 32.5%, and NOACs in 31%. The dose was in the low category in 22% of the cases discharged with NOACs, and half of the cases, who received NOACs at admission, were discharged with the same drug. Conclusion: NöroTekTR revealed the high but expected frequency of AF in acute stroke in Türkiye, as well as the aspects that could be improved in the management of secondary prophylaxis. AF is found in approximately one-third of hospitalized acute stroke cases in Türkiye. Effective anticoagulant therapy was not used in three-quarters of acute stroke cases with known AF. In AF, heparin, warfarin, and NOACs are planned at a similar frequency (one-third) within the scope of stroke secondary prophylaxis, and the prescribed NOAC dose is subtherapeutic in a quarter of the cases. Non-medical and medical education appears necessary to prevent stroke caused by AF. [ABSTRACT FROM AUTHOR]

Objective: Juvenile idiopathic arthritis (JIA) is a childhood rheumatic disease that causes joint inflammation and tissue damage. Non-infectious uveitis is the most common extra-articular manifestation of JIA.The aim of this study is to evaluate the risk factors that play a role in occurrence and recurrence of uveitis and, to determine the relationship between arthritis and uveitis activity in patients with JIA. Material and Methods: This retrospective, cross sectional study included JIA patients with/without uveitis from a referral center in Turkey. The Juvenile Arthritis Disease Activity Score was used to evaluate the disease activity and calculated for arthritis and uveitis separately. Results: Uveitis was seen in 26 (13.3%) of 195 JIA patients. Of 26 JIA associated uveitis (JIA-U) patients, 19 (73%) had an oligoarticular subtype. The median age at diagnosis of JIA with uveitis was younger than without uveitis (p=0.015). Oligoarticular JIA was found to be associated with recurrence of uveitis (p=0.021). The occurrence age of arthritis and uveitis was significantly younger in patients with recurrent uveitis (p=0.041, p=0.002, respectively). The median JADAS27 score at the onset of uveitis was lower in the recurrent group (p=0.038). Conclusion: Early age is a significant risk factor for occurrence and recurrence of uveitis. It is important to remember that, during the disease course, patients with low disease activity may also develop uveitis. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Ankara University Faculty of Medicine / Ankara Üniversitesi Tip Fakültesi Mecmuasi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ankara University Faculty of Medicine / Ankara Üniversitesi Tip Fakültesi Mecmuasi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Osmangazi Journal of Medicine / Osmangazi Tip Dergisi is the property of Eskisehir Osmangazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This report identifies clinical, Magnetic Resonance Imaging (MRI), surgical and histological findings of recurrent solitary spinal meningothelial meningioma in a dog. Five-year-old female Pomeranian dog with a history of severe cervicalgia was subjected. A solitary mass between C3-C4 vertebras were diagnosed by MRI, and surgery was carried out with successful results; however, clinical signs reappeared one year after surgery. Control MRI revealed the recurrence of the mass at the same location. Patient reoperated and it was histopathologically reconfirmed as meningothelial meningioma. In conclusion, reoperation of the recurrence of spinal meningioma can be suggested for the practitioners. [ABSTRACT FROM AUTHOR]

Copyright of Medical Journal of Ankara Training & Research Hospital is the property of Medical Journal of Ankara Training & Research Hospital and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Relapses are very common in Alcohol and Substance Use Disorders (ASUD). Although traumatic experiences are more common in patients with ASUD than in the normal population, its relationship with relapses has not been adequately studied. Method: Fifty-one patients who were hospitalized diagnosed with ASUD according to DSM 5 were included in the study. Sociodemographic Data Form, Impact of Events Scale-R (IES-R), Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Dissociative Experiences Scale (DES), Addiction Profile Index (API), The Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) and Traumatic Experiences Checklist (TEC) were applied during their hospitalization. Patients were evaluated for relapse in the 6th month after discharge. Results: Relapse was observed in 60.8% of the participants. A statistically significant difference was found between the groups with and without relapse in terms of previous psychiatric treatment, number of traumatic events and severity, neglect, emotional and physical abuse, HAM-A and DES scores (p<0.05). In the logistic regression analysis, it was found that not having previously applied for psychiatric treatment significantly predicted early relapses. Discussion: According to the study results, the previous psychiatric treatment seems to be associated with lower relapse rates. In contrast, traumatic experiences, anxiety, and dissociative symptoms seem to be associated with higher relapse rates. [ABSTRACT FROM AUTHOR]

Copyright of Aydin Dental Journal is the property of Aydin Dental Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Selcuk Dental Journal is the property of Selcuk Dental Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: The etiopathology of spongiofibrosis, which causes idiopathic urethral stricture, is not clear. Progressive inflammation may contribute to the development of urethral stricture. In our study, we aimed to investigate the relationship between inflammatory markers such as neutrophillymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), and platelet-lymphocyte ratio (PLR) and recurrence of idiopathic urethral stricture. Material and Method: Data of 40 patients who were diagnosed with primary idiopathic urethral stricture or having a relapse after treatment of idiopathic urethral stricture and 40 healthy control groups in our clinic were evaluated retrospectively. Results: Mean NLR, MLR and PLR values in the urethral stricture group were statistically significantly higher than the control group (p =0.042, p =0.023, p =0.02, respectively). In the urethral stricture group, 21 patients presented with recurrence, while 19 patients had primary idiopathic urethral stricture. Mean NLR, MLR, and PLR values were lower in those with relapse than in those without relapse. However, statist ically significant difference was found only in MLR values (p =0.009). Again, in the urethral stenosis group, no significant correlation was found between the number of recurrences or the length of the stenosis and inflammatory markers. Conclusion: The significantly higher inflammatory markers in the urethral stricture group compared to the control patients support that the etiopathogenesis of idiopathic urethral stricture is associated with an inflammatory process. However, the low markers in the relapsed group suggest that the main pathology is not inflammation, but may be associated with ischemia, microtrauma or developmental causes previously suggested in the etiopathogenesis of idiopathic urethral stricture. [ABSTRACT FROM AUTHOR]

Copyright of Osmangazi Journal of Medicine / Osmangazi Tip Dergisi is the property of Eskisehir Osmangazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim: The incidence of thyroid cancer has increased dramatically in recent decades. Multifocality is considered a poor prognostic factor for papillary thyroid carcinoma (PTC). Patients with multifocal PTC (MPTC) are at high risk for local recurrence, as well as lymphatic and distal metastases. This study examined the features and outcomes of MPTC. Material and Methods: This retrospective study was conducted on 300 patients with PTC. Patients were classified into a multifocal group and a unifocal group. The pathological features of the PTC and the patients' outcomes were analyzed and compared. Results: The multifocal group included 146 patients (48.7%), while the unifocal group included 154 patients (51.3%). The occurrence of multifocality was higher in females than in males (Odds ratio, OR: 2.37, 95% confidence interval, CI: 1.20-4.67, p=0.015). Tumor size of >1 cm in the multifocal group was larger than in the unifocal group (2.5 and 2.2 cm, respectively, p=0.021). Moreover, in multifocal group higher moderate risk of recurrence was detected than in the unifocal group (OR: 1.63, 95% CI: 1.01-2.60, p=0.044). At follow-up after treatment, MPTC patients had higher lymph node metastasis (OR: 2.89, 95% CI: 1.23-6.80, p=0.014). In addition, significantly higher thyroglobulin plasma levels (p=0.026) and disease recurrence (OR: 2.41, 95% CI: 1.05-5.52, p=0.037) were found in the multifocal group compared to the unifocal group. Conclusion: Patients with MPTC had a higher risk of disease recurrence, and multifocality was concluded to be an independent prognostic factor for overall disease recurrence. [ABSTRACT FROM AUTHOR]

Objective: The aim of present study is to evaluate a large clinical population of patients operated with diagnosis of ganglion in a single center over a 14-year period. Materials and Methods: One hundred and sixty-seven patients operated and histopathologically diagnosed with ganglion cyst located in hand and wrist were included in the study. The retrospectively analyzed parameters included age, gender, localization, clinical presentations, site, treatment methods and histopathological features. Recurrences, complications and outcomes were evaluated by phone calls. Statistical analyses and descriptive statistics were presented with frequencies and percentages. Results: The average age of the patients was 40,70 years (range 3-83 years). Majority of the patients (62,87%; n: 105) were in the 2nd – 4th decade of life. Pain and cosmetic concerns were the main complaints of the patients. The majority of the ganglions were located in the wrist (n: 114; 68,26%), and the majority of the wrist location was the dorsal side (n: 65). Mean follow-up time of 85 patients who could be reached by phone and agreed to participate in the study was 8,60 years. Recurrence rate among these patients was 7% (n: 6). Conclusion: The results of the present study were consistent with findings reported previously respect to patient age distribution, gender predominance and ganglion localization. Low recurrence rates can be achieved by complete resection of the cyst including the stalk and a cuff of adjacent tissue.

Objective: Etiology, diagnosis, and treatment of primary spontaneous pneumothorax (PSP) are not well-established and subject to debate in the pediatric age group. Our study aims to clarify the subject and discuss it in the light of available literature. Material and Methods: We performed a retrospective analysis of the age, sex, etiology, smoking habits, diagnostic methods, pneumothorax percentages, first treatment approach, and treatment results of the patients with PSP by examining the patients' records. A total of 71 patients, 65 (91.5%) male and six (8.5%) female, who were followed up and treated between 2010 and 2020 were included in the study. Descriptive statistical methods, Shapiro-Wilk test Mann-Whitney U test, Pearson chi-square test, Fisher's exact test, Fisher-Freeman-Halton exact test were used while evaluating the study data. Results: The mean age of the patients was 16.23±0.81 (13--18 years). The etiology was not clear in most of the patients. However, among them, 14 (25.5%) patients had bullae and 23 (32.4%) patients had a smoking habit. The diagnosis was made by means of taking medical history, physical examination, and post-anterior (PA) chest X-ray. Treatment with nasal oxygen was initiated in 14 (19.7%) patients with a pneumothorax percentage <20%. For a total of 57 patients the first line of treatment was initiated with tube thoracostomy. Video-assisted thoracoscopic surgery (VATS) was performed in cases where tube thoracostomy failed. Conclusion: Different forms of initial treatment modalities exist for spontaneous pneumothorax. However, we suggest that the first option in patients of the pediatric age group should be clinical follow-up and supportive treatment, if necessary, tube thoracostomy should be applied. [ABSTRACT FROM AUTHOR]

Copyright of Archives of the Turkish Society of Cardiology / Türk Kardiyoloji Derneği Arşivi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The cases of Guillain Barre Syndrome (GBS) have been reported following the coronavirus disease 2019 (COVID-19). Here, we describe a case that evolved from GBS to chronic inflammatory demyelinating polyneuropathy (CIDP) after COVID-19 in terms of contributing to the literature due to its different aspects. In the cerebrospinal fluid examination of the acute onset mixed type polyneuropathy case, albuminocytological dissociation was not detected. The patient was given a loading dose and monthly maintenance intravenous immunoglobulin (IVIG) for six months. Blood ferritin levels gradually decreased in parallel with clinical improvement. Four months after the IVIG treatment was terminated, the findings recurred and the CIDP was developed and IVIG treatment was continued. Long-term follow-up of post-COVID-19 GBS patients is important in terms of recurrence and chronicity. Ferritin level may be a biochemical marker in the clinical follow-up of these cases.

Copyright of Medical Records is the property of Medical Records and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Dental Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim: Periosteal chondroma is a rare chondroma that is difficult to differentiate. Its localization is similar to other surface periosteal lesions. These lesions have a wide distribution of age. Curettage, marginal excision, or en bloc resection are applied in the surgical treatment. En bloc resection is preferred to reduce recurrence. In this study, we aimed to share the experience of two orthopedic oncology centers in the differential diagnosis and treatment of periosteal chondroma. Material and Methods: Data from two clinics were analyzed retrospectively. Data were collected on demographic data (age, gender), clinical findings (pain, swelling, pressure-related symptom, duration of follow-up), radiological findings (size, bony invasion), pathology results (biopsy, excision), and postoperative complications (recurrence). Results: Fourteen patients were included in the study. En bloc resection was performed in all cases. The mean age of the patients was 31.5±16.5 (range, 8-58) years. 10 (71.4%) patients were male. The mean duration of symptoms was 6.6±4.8 (range, 0-18) months, and the mean follow-up was 46.7±39.6 (range, 6-132) months. Nine (64.3%) patients had pain. Six (42.9%) patients had swelling. One patient (7.1%) had a palpable mass. There was no complaint in 1 (7.1%) patient. One (7.1%) patient underwent biopsy. During the follow-up, no recurrence or complication was observed after en bloc resection. Conclusion: Imaging and histopathological findings of benign and malignant periosteal chondroid tumors may overlap, and accurate differential diagnosis is crucial in the treatment of these lesions. En bloc resection prevents recurrence during follow-up.

Objective: Acute mastoiditis (AM) is the most common complication associated with acute otitis media and plays a key role in the development of further complications. We identify the clinical characteristics, management, and outcome of patients with AM and to investigate the relationship between the development of recurrence and the treatment protocol of the first episode. Methods: Children hospitalized in our clinic due to a diagnosis of AM were retrospectively reviewed. Demographic data, disease-related symptoms, types of complications accompanied by AM, medical/surgical treatment modalities, culture results, laboratory findings, and presence of recurrence were screened. Laboratory findings were compared between those with and without accompanying complications, and between those with and without accompanying intracranial complications. Results: Of the 58 patients with AM, 24 (41.3%) had isolated AM. Complications associated with AM include subperiosteal abscess (61.7%), sigmoid sinus thrombosis (11.7%), facial paralysis (8.8%), petrositis with subperiosteal abscess (5.8%), meningitis (5.8%), facial paralysis with subperiosteal abscess (2.9%) and, epidural abscess with sigmoid sinus thrombosis (2.9%). Seven patients developed intracranial complications (12%), of whom one had more than one complication. Hemoglobin and hematocrit levels were found to be significantly lower in the presence of accompanying complications (p values, respectively p=0.000, p=0.000). C-reactive protein (CRP) levels were found to be significantly higher in the presence of intracranial complications (p=0.028). Recurrent AM developed in 9 patients (15.5%) during follow-up. There was no statistically significant relationship between the treatment protocol of the first episode and the development of recurrence (p=0.332). Conclusion: A conservative approach may be preferred for surgical treatment in patients without accompanying intratemporal or intracranial complications. Low hemoglobin and hematocrit levels, with the symptoms and imaging of the patients, may be a warning of the development of accompanying complications, and high CRP values may be a warning of accompanying intracranial complications. [ABSTRACT FROM AUTHOR]

Copyright of Ege Journal of Medicine is the property of Ege University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: The laser method (FiLaC™) has recently emerged as a minimally invasive treatment option in the treatment of anal fistula. Anal incontinence and fistula recurrence after anal fistula surgery are postoperative problems that complicate the treatment. In our study, we aimed to investigate the effectiveness of the film method in the treatment of anal fistula and in which cases it should be preferred in the treatment. Materials and Methods: Twelve patients who underwent FiLaC™ diode laser at Derik State Hospital between July 2017 and August 2018 were included in the study. Patients were analyzed retrospectively in terms of age, gender, development of incontinence, recovery and return to work, fistula types, MRI findings, and complications. Results: 11 of the patients included in the study were male and 1 female and the mean age was 46. Intraoperative complications were not observed in any of the patients. The mean follow-up period was 13.5 (7-19) months. Complete recovery was observed in 4 (33.3%) patients in the follow-ups of the patients, while no improvement was achieved in 8 (66.7%) patients. Conclusions: he FiLaCTM procedure for the treatment of anal fistula is a safe, minimally invasive, sphincter-sparing treatment option with low efficacy. However, it can be preferred as an initial treatment in high-level fistulas and in patients who want minimally invasive intervention. [ABSTRACT FROM AUTHOR]

Copyright of Van Tip Dergisi is the property of Yuzuncu Yil University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Öz Hepatoselüler karsinom en sık primer karaciğer malignitesi olup küratif tek tedavi seçeneği karaciğer transplantasyonudur. Kronik viral hepatit B’ye bağlı dekompanse karaciğer sirozu ve 5 cm.lik hepatoselüler karsinom odağı nedeniyle canlı vericili karaciğer transplantasyonu uygulanmış olan 67 yaşında erkek hastanın post-transplant 2. yılında tüm biyokimyasal verileri, abdominal ve toraks BT’si normal olmasına rağmen sırt ağrısı nedeniyle çekilen dorsal MR’da D7 seviyesinde 2.5 cm.lik nüks gelişmiştir. Radyoterapi ve sonrasında cerrahi uygulanmıştır. Karaciğer transplantasyonu sonrası nüksler sıklıkla ekstrahepatik alanlarda gelişmektedir. Nadiren de olsa kemik ağrısı olanlarda akılda bulundurulmalıdır. Erken tanı ile erken nüks tedavisi mümkün olmaktadır.

Objective: This study aimed to determine the oncological outcomes of mixed-grade tumors by comparing them with pure low-grade and high-grade tumors. Methods: We retrospectively reviewed the medical records of patients with primary non-muscle-invasive bladder cancer. Patients were categorized into three groups according to the histological grade of their tumors: low-grade, mixed-grade, and high-grade. Clinicopathological characteristics and oncological outcomes, such as recurrence-free survival (RFS), progression-free survival (PFS), and cancer-specific survival (CSS), were compared between the three groups. Results: A total of 369 patients (190 low, 40 mixed, and 139 high-grade) were included in our study, with a mean follow-up of 55.94±41.73 months. Patients with mixed-grade tumors had lower rates of pT1 stage diseases than those with high-grade tumors (42.5% vs. 64.0%, respectively) and higher rates than those with low-grade tumors (14.7% vs. 42.5%, respectively) (p=0.001). There was no significant difference in RFS between low-, mixed-, and high-grade tumor patients (p=0.887). Patients with mixed-grade tumors had worse PFS and CSS outcomes than those with low-grade tumors (199.84±23.22 vs. 214.94±15.92 for PFS and 202.07±19.86 vs. 233.61±9.84 for CSS, respectively) and better PFS and CSS outcomes than those with highgrade tumors (199.84±23.22 vs. 163.28±16.18 for PFS and 202.07±19.86 vs. 180.81±15.89 for CSS, respectively), although these comparisons were not statistically significant. Conclusions: Patients with mixed-grade tumors had worse PFS and CSS outcomes than patients with low-grade tumors and better PFS and CSS outcomes than patients with high-grade tumors, although these comparisons were not statistically significant. Our results should be verified by future studies. [ABSTRACT FROM AUTHOR]

Copyright of Pamukkale Medical Journal is the property of Pamukkale Journal of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: The treatment of Graves' disease (GD) with antithyroid drugs (ATD) is associated with a risk of relapse. The rate and predictive factors of GD are controversial. This study aimed to assess the relapse rate after the withdrawal of ATD in patients with GD, as well as to identify its predictive factors. Material and Methods: This was a retrospective cohort study covering 35 patients with GD that were treated with ATD. Relapse was defined as the state when hyperthyroidism was detected after the withdrawal of medical therapy. Relapse was studied by establishing the survival curve according to Kaplan-Meier's method. The Log-Rank test was used to compare the survival curves according to the clinical, biological, and therapeutic parameters of the patients. Results: The mean follow-up time after the withdrawal of ATD was 32.8±28.8 months. Relapse was observed in 13 patients (37%) after an average time of 7.8±8.8 months of ATD discontinuation. Factors associated with the risk of relapse were smoking (p=0.08), family history of thyroid disease (p=0.03), the presence of a triggering factor (p=0.004), FT4 level at the time of diagnosis at >2.3 times the normal range (p=0.002), thyroid-stimulating hormone level less than 0.76 mIU/L at three months after ATD withdrawal (p=0.05), and a benzylthiouracil dose of >125 mg/day at the time of ATD discontinuation (p=0.02). Conclusion: Relapse in patients with GD after the withdrawal of ATD is observed in almost a third of the patients. Identification of patients at a high risk of relapse is necessary to indicate radical treatment. [ABSTRACT FROM AUTHOR]

Amaç Nüks primer spontan pnömotoraksın cerrahi tedavisi, apikal bül rezeksiyonu ve plörodezisi içerir. Postoperatif nüks oranları %5 ile %10 arasında bildirilmektedir. Bu çalışmada, kliniğimizde uyguladığımız iki farklı mekanik plevral abrazyon yönteminin etkinliğini ve nüks oranlarını karşılaştırmayı amaçladık. Gereç ve Yöntem Ocak 2012 ve Aralık 2019 tarihleri arasında 112 hastaya primer spontan pnömotoraks için cerrahi tedavi olarak videotorakoskopik bül rezeksiyonu ve paryetal plevra abrazyonu uygulandı. Hastaların yaş, cinsiyet, sigara içme hikayesi, ameliyat nedeni, ameliyatta bül varlığı, plörodez yöntemi, göğüs tüpü drenaj süresi, hastanede yatış süresi, ameliyat sonrası komplikasyonlar, ameliyat sonrası nüks ve takipleri geriye dönük olarak incelendi. Bulgular Ameliyat endikasyonu, hastaların 91'inde (%81.2) nüks pnömotoraks iken 21'inde (%18.7) 7 günden fazla devam eden uzamış hava kaçağı idi. Paryetal plevraya mekanik plöredezis için abrazyon; 38 (%33.9) hastada gazlı bez ile uygulanırken, 74 (%66.1) hastada steril zımpara ile uygulandı. Paryetal plevra abrazyonu için steril zımpara kullandığımız grupta göğüs tüpü drenaj süresi, gazlı bez kullandığımız gruba göre istatistiksel olarak anlamı derecede yüksekti. Ancak steril zımpara kullandığımız grupta, nüks ve takip süresi istatistiksel olarak anlamlı derecede düşüktü. Diğer parametreler açısından iki grup arasında istatistiksel olarak anlamlı bir ilişki saptanmadı. Sonuç Sonuç olarak nüks primer spontan pnömotoraks veya uzamış hava kaçağı tedavisinde videotorakoskopik bül rezeksiyonu ve plevral abrazyon, düşük nüks oranı ile güvenli bir yöntemdir. Ayrıca paryetal plevra abrazyonu için steril zımpara kullanımı göğüs tüpü drenaj süresini bir miktar artırmakla birlikte daha az nüks oranına sahiptir. Objective Surgical treatment of recurrent primary spontaneous pneumothorax involves resection of apical bulla and pleurodesis. Postoperative recurrence rates between 5 and 10% are reported. In this study, we aimed to compare the effectiveness and recurrence rates of two different mechanical pleural abrasion methods that we applied in our clinic. Materials and Methods Between January 2012 and December 2019, 112 patients underwent videothoracoscopic bullectomy and parietal pleural abrasion as a surgical treatment for primary spontaneous pneumothorax. Patients' age, gender, smoking history, reason for surgery, presence of bulla in surgery, pleurodesis method, chest tube drainage time, length of hospital stay, postoperative complications, postoperative recurrence and follow-up were retrospectively analyzed. Results The indication for surgery was recurrent pneumothorax in 91 (81.2%) of the patients, while prolonged air leakage continued for more than 7 days in 21 (18.7%) patients. For mechanical pleurodesis to the parietal pleura, 38 (33.9%) patients were abrasion with gauze, while 74 (66.1%) patients were performed with sterile sandpaper. In the group where we used sterile sandpaper for parietal pleural abrasion, the chest tube drainage time was statistically significantly higher than the group in which we used gauze. However, the recurrence and follow-up time was statistically significantly lower in the group in which we used sterile sandpaper. There was no statistically significant relationship between the two groups in terms of other parameters. Discussion In conclusion, videothoracoscopic bullectomy and pleural abrasion is a safe method with low recurrence in the treatment of recurrent primary spontaneous pneumothorax or prolonged air leakage. In addition, the use of sterile sandpaper for parietal pleural abrasion increases the chest tube drainage time slightly but has less recurrence rate. [ABSTRACT FROM AUTHOR]

Amaç: İnflamatuar ve immünolojik olaylarda rol oynadığı bilinen mast hücresinin pterygium nüksündeki rolünü araştırmak için primer ve tekrarlayan pterygium doku örneklerinde mast hücre sayısını belirlemeyi ve anjiyogenez ile ilişkisini saptamayı amaçladık.Gereç ve Yöntem: Çalışmaya çıplak sklera tekniği ile primer pterjiyum eksizyonu yapılan, ancak bir süre sonra tekrarlayan pterjiyumlu 61 hasta dahil edildi. Aynı hastanın primer ve tekrarlayan pterygium doku örnekleri histopatolojik olarak incelendi. Ortalama mast hücre sayısı, 400x büyütmede ışık mikroskobu altında 3 farklı alandan sayılarak hesaplandı. Ek olarak, damarların sayısı 200x büyütmede skorlandı.Bulgular: Hastaların 34'ü erkek, 27'si kadındı. Yaş ortalaması 57.02 ± 7.96 yıl idi. Ortalama mast hücre sayısı, primer pterjiyum dokusunda 8.46 ± 2.52, tekrarlayan pterjiyum dokusunda 14.07 ± 3.05 idi. Ortalama vasküler sayı primer pterjiyum dokusunda 12.90 ± 3.17 ve tekrarlayan pterjiyumda 16.21 ± 2.24 idi. İstatistiksel analiz, tekrarlayan pterjiyumda mast hücre sayısında ve vasküler sayıda anlamlı bir artış olduğunu gösterdi. Primer pterjiyum ve tekrarlayan pterjiyum doku örneklerinde mast hücre sayısı ve vaskülerite korelasyon göstermekteydi. Sonuç: Pterjium dokusunda artmış mast hücresi, pterjiumun nüksünde önemli bir rol oynayabilir. Pterjium nüksünün önlenmesinde mast hücre sayısının belirlenmesi önemli olabilir.

Objective: To share our data and experiences of the primary and recurrent advanced larynx tumors. Material and Method: Recordings of patients which have undergone total laryngectomy between 2012-2019, for reccurence after primary radiotherapy is reviewed retrospectively. Patients were reviewed for age, gender, T stage, primary site of disease, transglottic extension, lymph node metastasis, extracapsular extension, whether thyroid gland excision is done and 5-year disease free survival rate. Results: Total laryngectomy is done in 81 patients of whom 60 (74%) were primary and 21 (26%) were recurrence cases after radiotherapy. Eighteen of the primary patients had metastatic lymph nodes, 15 patients had thyroid lobectomy and 7 patients had total thyroidectomy. The 5-years diseasefree survival rates were 58.3% in primary patients and 52.9% in salvage patients. Conclusion: Performing total laryngectomy after radiotherapy recurrence may cause additional comorbidities in the patient compared to the primary patients. We are in the consideration that, when making a choose between surgery and radiotherapy, the final decision should be made with patients by informing them about possible recurrences and secondary surgeries due to these recurrences in addition to the side effects of radiotherapy. [ABSTRACT FROM AUTHOR]

Objective: Lipoblastomas are benign tumors developing from embryonic fat tissue with few cases reported in the head and neck region. Herein, we aim to present the management of a rare type of lipoblastoma in childhood. Material and Methods: A retrospective chart review was performed on all patients who were admitted due to a mass in the neck and axillary region between January 2015 and December 2019. Data were collected on demographics, comorbidities, preoperative characteristics, operative interventions, and postoperative complications and outcomes. The patients with lipoblastoma were further analyzed. Results: There were 52 patients operated on due to a mass in the neck or axillary region during the study time. The mean age was 5.42±4.16. The majority of the patients (40/52) were diagnosed with enlarged lymph nodes of which 32 (80%) were diagnosed with lymphoma. Among these populations, only two (3.8%) of them were diagnosed with lipoblastoma. Both cases were asymptomatic other than a painless mass. The histopathological examination confirmed the diagnosis of lipoblastoma after surgical excision. Both cases have been uneventful for four years postoperatively. Conclusion: In conclusion, lipoblastomas emerge as a slowly growing mass in early childhood and are mostly seen on the trunk and extremities. Although benign, they have the potential to increase in size and invade adjacent tissues. The gold standard treatment is complete surgical excision. Due to the possibility of recurrence, regular follow-up is strongly recommended after surgery. [ABSTRACT FROM AUTHOR]

Aim: Periosteal chondroma is a rare chondroma that is difficult to differentiate. Its localization is similar to other surface periosteal lesions. These lesions have a wide distribution of age. Curettage, marginal excision, or en bloc resection are applied in the surgical treatment. En bloc resection is preferred to reduce recurrence. In this study, we aimed to share the experience of two orthopedic oncology centers in the differential diagnosis and treatment of periosteal chondroma. Material and Methods: Data from two clinics were analyzed retrospectively. Data were collected on demographic data (age, gender), clinical findings (pain, swelling, pressure-related symptom, duration of follow-up), radiological findings (size, bony invasion), pathology results (biopsy, excision), and postoperative complications (recurrence). Results: Fourteen patients were included in the study. En bloc resection was performed in all cases. The mean age of the patients was 31.5±16.5 (range, 8-58) years. 10 (71.4%) patients were male. The mean duration of symptoms was 6.6±4.8 (range, 0-18) months, and the mean follow-up was 46.7±39.6 (range, 6-132) months. Nine (64.3%) patients had pain. Six (42.9%) patients had swelling. One patient (7.1%) had a palpable mass. There was no complaint in 1 (7.1%) patient. One (7.1%) patient underwent biopsy. During the follow-up, no recurrence or complication was observed after en bloc resection. Conclusion: Imaging and histopathological findings of benign and malignant periosteal chondroid tumors may overlap, and accurate differential diagnosis is crucial in the treatment of these lesions. En bloc resection prevents recurrence during follow-up. [ABSTRACT FROM AUTHOR]

Amaç:Anevrizmal kemik kistinde tedavi tekniği,lezyonun anatomik bölgeleri, cinsiyet ve yaşınnüksoranlarıüzerindekietkilerivegörülmesıklığınınnaraştırılması.Gereç ve Yöntemler:Kliniğimizdeanevrizmal kemik kisti tanısıyla100hasta, geriye dönükolarakçalışmaya alındı. Çalışmamızdaparametreolarak farklıtedavitekniklerin nüksoranları,cinsiyeteve lezyonun lokalizasyonuna göregörülmesıklığıvenüksoranıelealındı.Bulgular:Hastaların45’ikadın,55’ierkek idi. Ortalama yaşı22(4-56)idi. Hastaların%54’iyirmi yaşınaltındaydı.22’siüstekstremite,55’ialt ekstremite ve 23’üpelvis ve vertebra’dankaynaklanıyordu.31’iküretajsonrasısementleme, 57’siküretajsonrasıgrefonajve 12’sirezeksiyonile tedavi edilmiş. Ortalamatakipsüremiz64,6(1-216) aydı.Toplam 16 (%22,53) nüksgörüldü.Buhastalarınbirinde2,birinde3keznüksgörülmüş. Nükslerinbirihariçhepsitedavidensonraki ilk iki sene içindegörülmüş. Bir hastada 9 yıl7aysonra nüksgörülmüş.Nükslerin8’ialt ekstremiteden 5’iüstekstremiteden ve 3’üpelvistenkaynaklanıyormuş. Nükslerin1’ibirincionyıllıkdönemde,8’iikincionyıllıkdönemde,6’sıüçüncüonyıllıkdönemdeve1’i(%6,25)dördüncüonyıllıkdönemdegörülmüş.Küretajsonrasıgrefonaj yapılmışhastaların%21.05’unda nüksgörülmüş. Küretajsonrasısementleme yapılanhastaların%12,90’indenüksgörülmüş.Sonuç:Agresif tedavi yapılanlardanüksolanıazaldığıgörülmekteancakküretaj-grefonajveyaküretaj-sementlemegibiyöntemlereekolarakadjuvantedavilerlekabul edilebilir sonuçlareldeedilebilir.Agresiftedavininrekonstrüksiyonuçokdahazorolacağıiçinnilktedaviseçeneğiolarakagresifyöntemlerkullanılmamasınıöneriyoruz.Nükslerinçoğuoperasyondansonrakiilkikiseneiçindegörüldüğüiçin,opereedilen lezyonlar en az iki sene takip altındatutulmalıdır.

The cases of Guillain Barre Syndrome (GBS) have been reported following the coronavirus disease 2019 (COVID-19). Here, we describe a case that evolved from GBS to chronic inflammatory demyelinating polyneuropathy (CIDP) after COVID-19 in terms of contributing to the literature due to its different aspects. In the cerebrospinal fluid examination of the acute onset mixed type polyneuropathy case, albuminocytological dissociation was not detected. The patient was given a loading dose and monthly maintenance intravenous immunoglobulin (IVIG) for six months. Blood ferritin levels gradually decreased in parallel with clinical improvement. Four months after the IVIG treatment was terminated, the findings recurred and the CIDP was developed and IVIG treatment was continued. Long-term follow-up of post- COVID-19 GBS patients is important in terms of recurrence and chronicity. Ferritin level may be a biochemical marker in the clinical follow-up of these cases. [ABSTRACT FROM AUTHOR]

Objective: Non-muscle invasive bladder cancer (NMIBC) accounts for 75% of all bladder cancer cases. Several models to predict relapses and progression have been developed. We aimed to determine the predictive value of the neutrophil-lymphocyte ratio (NLR) for recurrence and/or progression of the disease. Materials and Methods: Seventy patients with high-risk NMIBC according to the European Organization for Research and Treatment of Cancer (EORTC) risk classification who were receiving Bacillus Calmette-Guerin (BCG) treatment and were followed up at our clinic were included in the study. Results: The average score level and NLR values differed significantly on patient classification according to the EORTC Progression and Recurrence Risk score. The positive correlations among EORTC Recurrence score, EORTC Progression score, Club Urológico Espanol de Tratamiento Oncológico (CUETO) Recurrence score, and CUETO Progression score and NLR values were not statistically significant. The NLR values decreased significantly on follow-ups on BCG treatment. Conclusion: Patients with bladder cancer have a high NLR, which has predictive utility with regard to prognosis. A decrease in NLR with BCG treatment is indicative of the decreased likelihood of recurrence and progression. [ABSTRACT FROM AUTHOR]

Aim: The aim of this study was to compare the fibrin tissue adhesive technique with vicryl suture technique in autograft pterygium surgery . Patients and Methods: The files of the patients who underwent surgery between June 2016 and August 2019 were retrospectively reviewed. Seventy two patients (Group 1) who underwent autograft pterygium surgery with vicryl suture technique (Primary pterygium Group 1a, recurrent pterygium Group 1b) and 58 patients who underwent autograft pterygium surgery with fibrin tissue adhesive technique (Primary pterygium Group 2a, recurrent pterygium Group 2b) were included . Results: The mean age of the patients was 47.04±5.70 years (ranging between 37-65) in Group 1 and 47.10±4.88 years (ranging between 38-57) in Group 2. There was not a statistically significant difference in terms of age between two groups (p=0.95). The mean duration of the surgery was 24.91±3.08 min, 25.60±2.20 min, 17.62±2.57 min, and 18.84±2.83 min in groups 1a, 1b, 2a and 2b, respectively. There were statistically significant differences in terms of the duration of the surgery between groups 1a and 1b (p=0.021), groups 2a and 2b (p=0.001), groups 1 and 2 (p<0.001). Recurrence pterygium was found to require more surgery time in both techniques. Postoperative recurrence was not observed in any of the patients. Conclusion: Pterygium surgery with conjunctival autograft is a reliable surgical method with low recurrence rates. The duration of surgery in recurrent pterygium was found to be longer in both surgical techniques. It is concluded that autograft pterygium surgery with fibrin tissue adhesive is the preferred surgical method that shortens the duration of the surgery. [ABSTRACT FROM AUTHOR]