1. Antibacterial and antioxidant activities of a new phenolic coumpound from the roots barks of Cassia arereh Delile (Fabaceae)
- Author
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Néomi Chefo Kengne, Honoré Wangso, Isaac Silvère Gade, Alphonse Laya, Jean Paul Bayang, Benoît Bargui Koubala, Sophie Laurent, Celine Henoumont, and Emmanuel Talla
- Subjects
Cassia arereh ,Phenolic compound ,Antibacterial activity ,Antioxidant activity ,Chemistry ,QD1-999 - Abstract
Phytochemical study of the root barks of Cassia arereh resulted in the isolation of a new phenolic ester, 3′-hydroxy-4′-methoxystyrenyl-(E)-p-coumarate (1) isolated for the first time from natural source, alongside eight known compounds (2–9). Compounds 1, 7 and 8 are depicted for the first time from Cassia genus. The structures of all compounds were established through NMR analysis (1D and 2D), High Resolution Mass Spectrometry (HRMS) and comparison with previously reported data in literature. Antioxidant activity was investigated through DPPH method while the antibacterial activity was done by the disc diffusion method on Escherichia coli and Salmonella typhimurium strains. Results showed that the methanol extract and compound 7 displayed significant (p
- Published
- 2024
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