1. Interferon Gamma in Sickness Predisposing to Mycobacterial Infectious Diseases
- Author
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Gemici Karaaslan B, Rosain J, Bustamante J, and Kıykım A
- Subjects
- Humans, Genetic Predisposition to Disease, Interferon-gamma administration & dosage, Interferon-gamma deficiency, Interferon-gamma immunology, Mycobacterium Infections genetics, Mycobacterium Infections immunology, Mycobacterium Infections prevention & control
- Abstract
In recent decades, the prevalence of inborn errors of immunity has increased, necessitating the development of more effective treatment and care options for these highly morbid conditions. Due to these “experiments of nature,” the complicated nature of the immune system is being revealed. Based on the functional and molecular tests, targeted therapies are now being developed which offer a more effective approach and reduce damage. This study aimed to investigate a key cytokine of the cellular immune response, interferon‐gamma (IFN-γ), which is linked to Mendelian susceptibility to Mycobacterial disease, and its potential as a therapeutic option for IFN-γ deficiency., Competing Interests: Conflict of Interest: The authors declare that they have no conflict of interest.
- Published
- 2024
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