Search

Your search keyword '"Mutis, Tuna"' showing total 722 results
Start Over Author "Mutis, Tuna"
722 results on '"Mutis, Tuna"'

1. Distinct peripheral T-cell and NK-cell profiles in HGBL-MYC/BCL2 vs patients with DLBCL NOS

Author

de Jonge, A. Vera, Duetz, Carolien, Bruins, Wassilis S. C., Korst, Charlotte L. B. M., Rentenaar, Rosa, Cosovic, Meliha, Eken, Merve, Twickler, Inoka, Nijland, Marcel, van der Poel, Marjolein W. M., de Heer, Koen, Klerk, Clara P. W., Strobbe, Leonie, Oosterveld, Margriet, Boersma, Rinske, Koene, Harry R., Roemer, Margaretha G. M., van Werkhoven, Erik, Chamuleau, Martine E. D., and Mutis, Tuna

Published
2024
Full Text
View/download PDF

2. Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity

Author

Hiemstra, Ida H., Santegoets, Kim C.M., Janmaat, Maarten L., De Goeij, Bart E.C.G., Ten Hagen, Wessel, van Dooremalen, Sanne, Boross, Peter, van den Brakel, Jeroen, Bosgra, Sieto, Andringa, Grietje, van Kessel-Welmers, Berris, Verzijl, Dennis, Hibbert, Richard G., Frerichs, Kristine A., Mutis, Tuna, van de Donk, Niels W.C.J., Ahmadi, Tahamtan, Satijn, David, Sasser, A. Kate, and Breij, Esther C.W.

Published
2023
Full Text
View/download PDF

3. Tumour Escape from CAR-T Cells

Author

Rasche, Leo, Vago, Luca, Mutis, Tuna, Kröger, Nicolaus, editor, Gribben, John, editor, Chabannon, Christian, editor, Yakoub-Agha, Ibrahim, editor, and Einsele, Hermann, editor

Published
2022
Full Text
View/download PDF

4. Enhancing Fc‐mediated effector functions of monoclonal antibodies: The example of HexaBodies.

Author

Horst, Hilma J. and Mutis, Tuna

Subjects
*CELL surface antigens, *IMMUNE response, *CYTOTOXINS, *MULTIPLE myeloma, *CANCER treatment, *CD20 antigen
Abstract

Summary Since the approval of the CD20‐targeting monoclonal antibody (mAb) rituximab for the treatment of lymphoma in 1997, mAb therapy has significantly transformed cancer treatment. With over 90 FDA‐approved mAbs for the treatment of various hematological and solid cancers, modern cancer treatment relies heavily on these therapies. The overwhelming success of mAbs as cancer therapeutics is attributed to their broad applicability, high safety profile, and precise targeting of cancer‐associated surface antigens. Furthermore, mAbs can induce various anti‐tumor cytotoxic effector mechanisms including antibody‐dependent cellular cytotoxicity (ADCC), antibody‐dependent cellular phagocytosis (ADCP), and complement‐dependent cytotoxicity (CDC), all of which are mediated via their fragment crystallizable (Fc) domain. Over the past decades, these effector mechanisms have been substantially improved through Fc domain engineering. In this review, we will outline the different approaches to enhance Fc effector functions via Fc engineering of mAbs, with a specific emphasis on the so‐called “HexaBody” technology, which is designed to enhance the hexamerization of mAbs on the target cell surface, thereby inducing greater complement activation, CDC, and receptor clustering. The review will summarize the development, preclinical, and clinical testing of several HexaBodies designed for the treatment of B‐cell malignancies, as well as the potential use of the HexaBody technology beyond Fc‐mediated effector functions. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

6. T cell characteristics impact response and resistance to T cell-redirecting bispecific antibodies in multiple myeloma

Author

Verkleij, Christie P.M., primary, O'Neill, Chloe A., additional, Broekmans, Marloes E.C., additional, Frerichs, Kristine A., additional, Bruins, Wassilis S.C., additional, Duetz, Carolien, additional, Kruyswijk, Sandy, additional, Baglio, Serena R., additional, Skerget, Sheri, additional, Montes de Oca, Rocio, additional, Zweegman, Sonja, additional, Verona, Raluca I., additional, Mutis, Tuna, additional, and van de Donk, Niels W.C.J., additional

Published
2024
Full Text
View/download PDF

7. Preclinical activity and determinants of response of the GPRC5DxCD3 bispecific antibody talquetamab in multiple myeloma

Author

Verkleij, Christie P.M., Broekmans, Marloes E.C., van Duin, Mark, Frerichs, Kristine A., Kuiper, Rowan, de Jonge, A. Vera, Kaiser, Martin, Morgan, Gareth, Axel, Amy, Boominathan, Rengasamy, Sendecki, Jocelyn, Wong, Amy, Verona, Raluca I., Sonneveld, Pieter, Zweegman, Sonja, Adams, Homer C., III, Mutis, Tuna, and van de Donk, Niels W.C.J.

Published
2021
Full Text
View/download PDF

9. Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab

Author

Casneuf, Tineke, Adams, III, Homer C., van de Donk, Niels W.C.J., Abraham, Yann, Bald, Jaime, Vanhoof, Greet, Van der Borght, Koen, Smets, Tina, Foulk, Brad, Nielsen, Karl C., Rusbuldt, Joshua, Axel, Amy, Lysaght, Andrew, Ceulemans, Hugo, Stevenaert, Frederik, Usmani, Saad Z., Plesner, Torben, Avet-Loiseau, Herve, Nijhof, Inger, Mutis, Tuna, Schecter, Jordan M., Chiu, Christopher, and Bahlis, Nizar J.

Published
2021
Full Text
View/download PDF

11. A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy

Author

Kuiper, Jonas JW, Van Setten, Jessica, Ripke, Stephan, Van ‘T Slot, Ruben, Mulder, Flip, Missotten, Tom, Baarsma, G Seerp, Francioli, Laurent C, Pulit, Sara L, De Kovel, Carolien GF, Loon, Ninette Ten Dam-Van, Hollander, Anneke I Den, Veld, Paulien Huis in het, Hoyng, Carel B, Cordero-Coma, Miguel, Martín, Javier, Llorenç, Victor, Arya, Bharti, Thomas, Dhanes, Bakker, Steven C, Ophoff, Roel A, Rothova, Aniki, De Bakker, Paul IW, Mutis, Tuna, and Koeleman, Bobby PC

Subjects
Genetics, Prevention, Clinical Research, Autoimmune Disease, Human Genome, 2.1 Biological and endogenous factors, Aetiology, Inflammatory and immune system, Alleles, Aminopeptidases, Birdshot Chorioretinopathy, Case-Control Studies, Chorioretinitis, Female, Genome-Wide Association Study, HLA-A Antigens, Haplotypes, Humans, Male, Whites, White People, Biological Sciences, Medical and Health Sciences, Genetics & Heredity
Abstract

Birdshot chorioretinopathy (BSCR) is a rare form of autoimmune uveitis that can lead to severe visual impairment. Intriguingly, >95% of cases carry the HLA-A29 allele, which defines the strongest documented HLA association for a human disease. We have conducted a genome-wide association study in 96 Dutch and 27 Spanish cases, and 398 unrelated Dutch and 380 Spanish controls. Fine-mapping the primary MHC association through high-resolution imputation at classical HLA loci, identified HLA-A*29:02 as the principal MHC association (odds ratio (OR) = 157.5, 95% CI 91.6-272.6, P = 6.6 × 10(-74)). We also identified two novel susceptibility loci at 5q15 near ERAP2 (rs7705093; OR = 2.3, 95% CI 1.7-3.1, for the T allele, P = 8.6 × 10(-8)) and at 14q32.31 in the TECPR2 gene (rs150571175; OR = 6.1, 95% CI 3.2-11.7, for the A allele, P = 3.2 × 10(-8)). The association near ERAP2 was confirmed in an independent British case-control samples (combined meta-analysis P = 1.7 × 10(-9)). Functional analyses revealed that the risk allele of the polymorphism near ERAP2 is strongly associated with high mRNA and protein expression of ERAP2 in B cells. This study further defined an extremely strong MHC risk component in BSCR, and detected evidence for a novel disease mechanism that affects peptide processing in the endoplasmic reticulum.

Published
2014

12. Data from Specific Targeting of Multiple Myeloma by Dual Split-signaling Chimeric Antigen Receptor T cells Directed against CD38 and CD138

Author

van der Schans, Jort J., primary, Wang, Ziyu, primary, van Arkel, Jennemiek, primary, van Schaik, Thijs, primary, Katsarou, Afroditi, primary, Ruiter, Ruud, primary, Baardemans, Thomas, primary, Yuan, Huipin, primary, de Bruijn, Joost, primary, Zweegman, Sonja, primary, van de Donk, Niels W.C.J., primary, Groen, Richard W.J., primary, Themeli, Maria, primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

13. Supplemental Figures 1 from Specific Targeting of Multiple Myeloma by Dual Split-signaling Chimeric Antigen Receptor T cells Directed against CD38 and CD138

Author

van der Schans, Jort J., primary, Wang, Ziyu, primary, van Arkel, Jennemiek, primary, van Schaik, Thijs, primary, Katsarou, Afroditi, primary, Ruiter, Ruud, primary, Baardemans, Thomas, primary, Yuan, Huipin, primary, de Bruijn, Joost, primary, Zweegman, Sonja, primary, van de Donk, Niels W.C.J., primary, Groen, Richard W.J., primary, Themeli, Maria, primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

14. Supplementary Table 1 from Specific Targeting of Multiple Myeloma by Dual Split-signaling Chimeric Antigen Receptor T cells Directed against CD38 and CD138

Author

van der Schans, Jort J., primary, Wang, Ziyu, primary, van Arkel, Jennemiek, primary, van Schaik, Thijs, primary, Katsarou, Afroditi, primary, Ruiter, Ruud, primary, Baardemans, Thomas, primary, Yuan, Huipin, primary, de Bruijn, Joost, primary, Zweegman, Sonja, primary, van de Donk, Niels W.C.J., primary, Groen, Richard W.J., primary, Themeli, Maria, primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

16. Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatment

Author

van der Horst, Hilma J., de Jonge, A. Vera, Hiemstra, Ida H., Gelderloos, Anne T., Berry, Daniella R. A. I., Hijmering, Nathalie J., van Essen, Hendrik F., de Jong, Daphne, Chamuleau, Martine E. D., Zweegman, Sonja, Breij, Esther C. W., Roemer, Margaretha G. M., and Mutis, Tuna

Published
2021
Full Text
View/download PDF

17. Specific Targeting of Multiple Myeloma by Dual Split-signaling Chimeric Antigen Receptor T cells Directed against CD38 and CD138

Author

van der Schans, Jort J., primary, Wang, Ziyu, additional, van Arkel, Jennemiek, additional, van Schaik, Thijs, additional, Katsarou, Afroditi, additional, Ruiter, Ruud, additional, Baardemans, Thomas, additional, Yuan, Huipin, additional, de Bruijn, Joost, additional, Zweegman, Sonja, additional, van de Donk, Niels W.C.J., additional, Groen, Richard W.J., additional, Themeli, Maria, additional, and Mutis, Tuna, additional

Published
2023
Full Text
View/download PDF

20. DuoHexaBody-CD37®, a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies

Author

Oostindie, Simone C., van der Horst, Hilma J., Kil, Laurens P., Strumane, Kristin, Overdijk, Marije B., van den Brink, Edward N., van den Brakel, Jeroen H. N., Rademaker, Hendrik J., van Kessel, Berris, van den Noort, Juliette, Chamuleau, Martine E. D., Mutis, Tuna, Lindorfer, Margaret A., Taylor, Ronald P., Schuurman, Janine, Parren, Paul W. H. I., Beurskens, Frank J., and Breij, Esther C. W.

Published
2020
Full Text
View/download PDF

21. Contributors

Author

Aguilar, Ethan George, primary, Alatrash, Gheath, additional, Anasetti, Claudio, additional, Arvindam, Upasana Sunil, additional, Blazar, Bruce R., additional, Bousso, Philippe, additional, Byersdorfer, Craig, additional, Chilkulwar, Abhishek R., additional, Coghill, James M., additional, Cooke, Kenneth R., additional, Crain, Alyssa K., additional, Drobyski, William R., additional, Dudakov, Jarrod A., additional, Edinger, Matthias, additional, Felices, Martin, additional, Fry, Terry J., additional, Fowler, Daniel H., additional, Goulmy, Els, additional, Hanash, Alan M., additional, Hill, Geoffrey R., additional, Hoffmann, Petra, additional, Holler, Ernst, additional, Holtan, Shernan, additional, Jacoby, Elad, additional, Jenq, Robert R., additional, Kean, Leslie, additional, Levy, Robert B., additional, Markey, Kate A., additional, Martin, Paul J., additional, Michonneau, David, additional, Miller, Jeffrey, additional, Molldrem, Jeffrey J., additional, Murphy, William, additional, Mutis, Tuna, additional, Negrin, Robert S., additional, Paczesny, Sophie, additional, Penack, Olaf, additional, Petersdorf, Effie, additional, Piper, Clint, additional, Reddy, Pavan, additional, Ritz, Jerome, additional, Sarantopoulos, Stefanie, additional, Serody, Jonathan S., additional, Socié, Gérard, additional, Takashima, Shuichiro, additional, van den Brink, Marcel R.M., additional, Weber, Daniela, additional, Wu, Yongxia, additional, Yu, Xue-Zhong, additional, and Zeiser, Robert, additional

Published
2019
Full Text
View/download PDF

25. NK Cell Phenotype Is Associated With Response and Resistance to Daratumumab in Relapsed/Refractory Multiple Myeloma

Author

Verkleij, Christie P.M., primary, Frerichs, Kristine A., additional, Broekmans, Marloes E.C., additional, Duetz, Carolien, additional, O’Neill, Chloe A., additional, Bruins, Wassilis S.C., additional, Homan-Weert, Paola M., additional, Minnema, Monique C., additional, Levin, Mark-David, additional, Broijl, Annemiek, additional, Bos, Gerard M.J., additional, Kersten, Marie José, additional, Klein, Saskia K., additional, Shikhagaie, Medya M., additional, Casneuf, Tineke, additional, Abraham, Yann, additional, Smets, Tina, additional, Vanhoof, Greet, additional, Cortes-Selva, Diana, additional, van Steenbergen, Laure, additional, Ramos, Elena, additional, Verona, Raluca I., additional, Krevvata, Maria, additional, Sonneveld, Pieter, additional, Zweegman, Sonja, additional, Mutis, Tuna, additional, and van de Donk, Niels W.C.J., additional

Published
2023
Full Text
View/download PDF

26. Supplementary Figure 1 from T Cells Specific for an Unconventional Natural Antigen Fail to Recognize Leukemic Cells

Author

Pont, Margot J., primary, Oostvogels, Rimke, primary, van Bergen, Cornelis A.M., primary, van der Meijden, Edith D., primary, Honders, Maria W., primary, Bliss, Sophie, primary, Jongsma, Marlieke L.M., primary, Lokhorst, Henk M., primary, Falkenburg, J.H. Frederik, primary, Mutis, Tuna, primary, Griffioen, Marieke, primary, and Spaapen, Robbert M., primary

Published
2023
Full Text
View/download PDF

27. Supplementary Figure 2 from T Cells Specific for an Unconventional Natural Antigen Fail to Recognize Leukemic Cells

Author

Pont, Margot J., primary, Oostvogels, Rimke, primary, van Bergen, Cornelis A.M., primary, van der Meijden, Edith D., primary, Honders, Maria W., primary, Bliss, Sophie, primary, Jongsma, Marlieke L.M., primary, Lokhorst, Henk M., primary, Falkenburg, J.H. Frederik, primary, Mutis, Tuna, primary, Griffioen, Marieke, primary, and Spaapen, Robbert M., primary

Published
2023
Full Text
View/download PDF

28. Data from T Cells Specific for an Unconventional Natural Antigen Fail to Recognize Leukemic Cells

Author

Pont, Margot J., primary, Oostvogels, Rimke, primary, van Bergen, Cornelis A.M., primary, van der Meijden, Edith D., primary, Honders, Maria W., primary, Bliss, Sophie, primary, Jongsma, Marlieke L.M., primary, Lokhorst, Henk M., primary, Falkenburg, J.H. Frederik, primary, Mutis, Tuna, primary, Griffioen, Marieke, primary, and Spaapen, Robbert M., primary

Published
2023
Full Text
View/download PDF

29. Supplementary Data from Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies

Author

Lu, Haihui, primary, Molony, Ryan D., primary, Chen, Dongshu, primary, Jang, Sunyoung, primary, Wolf, Babette, primary, Ewert, Stefan, primary, Flaherty, Meghan, primary, Xu, Fangmin, primary, Isim, Sinan, primary, Shim, Yeonju, primary, Dornelas, Christina, primary, Balke, Nicole, primary, Leber, Xavier Charles, primary, Scharenberg, Meike, primary, Koelln, Johanna, primary, Choi, Eugene, primary, Ward, Rebecca, primary, Johnson, Jennifer, primary, Calzascia, Thomas, primary, Isnardi, Isabelle, primary, Williams, Juliet A., primary, Lindenbergh, Pieter L., primary, van de Donk, Niels W.C.J., primary, Mutis, Tuna, primary, Huet, Heather, primary, Lees, Emma, primary, and Meyer, Matthew J., primary

Published
2023
Full Text
View/download PDF

30. Supplementary Figures from Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies

Author

Lu, Haihui, primary, Molony, Ryan D., primary, Chen, Dongshu, primary, Jang, Sunyoung, primary, Wolf, Babette, primary, Ewert, Stefan, primary, Flaherty, Meghan, primary, Xu, Fangmin, primary, Isim, Sinan, primary, Shim, Yeonju, primary, Dornelas, Christina, primary, Balke, Nicole, primary, Leber, Xavier Charles, primary, Scharenberg, Meike, primary, Koelln, Johanna, primary, Choi, Eugene, primary, Ward, Rebecca, primary, Johnson, Jennifer, primary, Calzascia, Thomas, primary, Isnardi, Isabelle, primary, Williams, Juliet A., primary, Lindenbergh, Pieter L., primary, van de Donk, Niels W.C.J., primary, Mutis, Tuna, primary, Huet, Heather, primary, Lees, Emma, primary, and Meyer, Matthew J., primary

Published
2023
Full Text
View/download PDF

31. Supplementary Figure Legends from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance

Author

de Haart, Sanne J., primary, van de Donk, Niels W.C.J., primary, Minnema, Monique C., primary, Huang, Julie H., primary, Aarts-Riemens, Tineke, primary, Bovenschen, Niels, primary, Yuan, Huipin, primary, Groen, Richard W.J., primary, McMillin, Douglas W., primary, Jakubikova, Jana, primary, Lokhorst, Henk M., primary, Martens, Anton C., primary, Mitsiades, Constantine S., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

32. Supplementary Data from Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor–engineered T Cells

Author

Drent, Esther, primary, Poels, Renée, primary, Ruiter, Ruud, primary, van de Donk, Niels W.C.J., primary, Zweegman, Sonja, primary, Yuan, Huipin, primary, de Bruijn, Joost, primary, Sadelain, Michel, primary, Lokhorst, Henk M., primary, Groen, Richard W.J., primary, Mutis, Tuna, primary, and Themeli, Maria, primary

Published
2023
Full Text
View/download PDF

34. Supplementary Figure 3 from Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab

Author

Krejcik, Jakub, primary, Frerichs, Kris A., primary, Nijhof, Inger S., primary, van Kessel, Berris, primary, van Velzen, Jeroen F., primary, Bloem, Andries C., primary, Broekmans, Marloes E.C., primary, Zweegman, Sonja, primary, van Meerloo, Johan, primary, Musters, René J.P., primary, Poddighe, Pino J., primary, Groen, Richard W.J., primary, Chiu, Christopher, primary, Plesner, Torben, primary, Lokhorst, Henk M., primary, Sasser, A. Kate, primary, Mutis, Tuna, primary, and van de Donk, Niels W.C.J., primary

Published
2023
Full Text
View/download PDF

35. Supplementary Figure 2 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance

Author

de Haart, Sanne J., primary, van de Donk, Niels W.C.J., primary, Minnema, Monique C., primary, Huang, Julie H., primary, Aarts-Riemens, Tineke, primary, Bovenschen, Niels, primary, Yuan, Huipin, primary, Groen, Richard W.J., primary, McMillin, Douglas W., primary, Jakubikova, Jana, primary, Lokhorst, Henk M., primary, Martens, Anton C., primary, Mitsiades, Constantine S., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

36. Supplementary Figure 3 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance

Author

de Haart, Sanne J., primary, van de Donk, Niels W.C.J., primary, Minnema, Monique C., primary, Huang, Julie H., primary, Aarts-Riemens, Tineke, primary, Bovenschen, Niels, primary, Yuan, Huipin, primary, Groen, Richard W.J., primary, McMillin, Douglas W., primary, Jakubikova, Jana, primary, Lokhorst, Henk M., primary, Martens, Anton C., primary, Mitsiades, Constantine S., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

37. Supplementary Figure 1 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance

Author

de Haart, Sanne J., primary, van de Donk, Niels W.C.J., primary, Minnema, Monique C., primary, Huang, Julie H., primary, Aarts-Riemens, Tineke, primary, Bovenschen, Niels, primary, Yuan, Huipin, primary, Groen, Richard W.J., primary, McMillin, Douglas W., primary, Jakubikova, Jana, primary, Lokhorst, Henk M., primary, Martens, Anton C., primary, Mitsiades, Constantine S., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

38. Supplementary Figure 4 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance

Author

de Haart, Sanne J., primary, van de Donk, Niels W.C.J., primary, Minnema, Monique C., primary, Huang, Julie H., primary, Aarts-Riemens, Tineke, primary, Bovenschen, Niels, primary, Yuan, Huipin, primary, Groen, Richard W.J., primary, McMillin, Douglas W., primary, Jakubikova, Jana, primary, Lokhorst, Henk M., primary, Martens, Anton C., primary, Mitsiades, Constantine S., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

39. Supplemental Data from Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab

Author

Krejcik, Jakub, primary, Frerichs, Kris A., primary, Nijhof, Inger S., primary, van Kessel, Berris, primary, van Velzen, Jeroen F., primary, Bloem, Andries C., primary, Broekmans, Marloes E.C., primary, Zweegman, Sonja, primary, van Meerloo, Johan, primary, Musters, René J.P., primary, Poddighe, Pino J., primary, Groen, Richard W.J., primary, Chiu, Christopher, primary, Plesner, Torben, primary, Lokhorst, Henk M., primary, Sasser, A. Kate, primary, Mutis, Tuna, primary, and van de Donk, Niels W.C.J., primary

Published
2023
Full Text
View/download PDF

40. Supplementary Data from Preclinical Activity of JNJ-7957, a Novel BCMA×CD3 Bispecific Antibody for the Treatment of Multiple Myeloma, Is Potentiated by Daratumumab

Author

Frerichs, Kristine A., primary, Broekmans, Marloes E.C., primary, Marin Soto, Jhon A., primary, van Kessel, Berris, primary, Heymans, Martijn W., primary, Holthof, Lisa C., primary, Verkleij, Christie P.M., primary, Boominathan, Rengasamy, primary, Vaidya, Bhavesh, primary, Sendecki, Jocelyn, primary, Axel, Amy, primary, Gaudet, Francois, primary, Pillarisetti, Kodandaram, primary, Zweegman, Sonja, primary, Adams, Homer C., primary, Mutis, Tuna, primary, and van de Donk, Niels W.C.J., primary

Published
2023
Full Text
View/download PDF

43. Supplementary Figure 6 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance

Author

de Haart, Sanne J., primary, van de Donk, Niels W.C.J., primary, Minnema, Monique C., primary, Huang, Julie H., primary, Aarts-Riemens, Tineke, primary, Bovenschen, Niels, primary, Yuan, Huipin, primary, Groen, Richard W.J., primary, McMillin, Douglas W., primary, Jakubikova, Jana, primary, Lokhorst, Henk M., primary, Martens, Anton C., primary, Mitsiades, Constantine S., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

45. Table S1 and Figures S1-10 from Bone Marrow Mesenchymal Stromal Cells Can Render Multiple Myeloma Cells Resistant to Cytotoxic Machinery of CAR T Cells through Inhibition of Apoptosis

Author

Holthof, Lisa C., primary, van der Schans, Jort J., primary, Katsarou, Afroditi, primary, Poels, Renée, primary, Gelderloos, Anne T., primary, Drent, Esther, primary, van Hal-van Veen, Susan E., primary, Li, Fengzhi, primary, Zweegman, Sonja, primary, van de Donk, Niels W.C.J., primary, Themeli, Maria, primary, Groen, Richard W.J., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

46. Supplementary Figure 5 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance

Author

de Haart, Sanne J., primary, van de Donk, Niels W.C.J., primary, Minnema, Monique C., primary, Huang, Julie H., primary, Aarts-Riemens, Tineke, primary, Bovenschen, Niels, primary, Yuan, Huipin, primary, Groen, Richard W.J., primary, McMillin, Douglas W., primary, Jakubikova, Jana, primary, Lokhorst, Henk M., primary, Martens, Anton C., primary, Mitsiades, Constantine S., primary, and Mutis, Tuna, primary

Published
2023
Full Text
View/download PDF

47. NK Cell Phenotype Is Associated With Response and Resistance to Daratumumab in Relapsed/Refractory Multiple Myeloma

Author

MS Hematologie, Cancer, Infection & Immunity, Regenerative Medicine and Stem Cells, Verkleij, Christie P M, Frerichs, Kristine A, Broekmans, Marloes E C, Duetz, Carolien, O'Neill, Chloe A, Bruins, Wassilis S C, Homan-Weert, Paola M, Minnema, Monique C, Levin, Mark-David, Broijl, Annemiek, Bos, Gerard M J, Kersten, Marie José, Klein, Saskia K, Shikhagaie, Medya M, Casneuf, Tineke, Abraham, Yann, Smets, Tina, Vanhoof, Greet, Cortes-Selva, Diana, van Steenbergen, Laure, Ramos, Elena, Verona, Raluca I, Krevvata, Maria, Sonneveld, Pieter, Zweegman, Sonja, Mutis, Tuna, van de Donk, Niels W C J, MS Hematologie, Cancer, Infection & Immunity, Regenerative Medicine and Stem Cells, Verkleij, Christie P M, Frerichs, Kristine A, Broekmans, Marloes E C, Duetz, Carolien, O'Neill, Chloe A, Bruins, Wassilis S C, Homan-Weert, Paola M, Minnema, Monique C, Levin, Mark-David, Broijl, Annemiek, Bos, Gerard M J, Kersten, Marie José, Klein, Saskia K, Shikhagaie, Medya M, Casneuf, Tineke, Abraham, Yann, Smets, Tina, Vanhoof, Greet, Cortes-Selva, Diana, van Steenbergen, Laure, Ramos, Elena, Verona, Raluca I, Krevvata, Maria, Sonneveld, Pieter, Zweegman, Sonja, Mutis, Tuna, and van de Donk, Niels W C J

Published
2023

48. Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma

Author

Nijhof, Inger S., Franssen, Laurens E., Levin, Mark-David, Bos, Gerard M.J., Broijl, Annemiek, Klein, Saskia K., Koene, Harry R., Bloem, Andries C., Beeker, Aart, Faber, Laura M., van der Spek, Ellen, Ypma, Paula F., Raymakers, Reinier, van Spronsen, Dick-Johan, Westerweel, Peter E., Oostvogels, Rimke, van Velzen, Jeroen, van Kessel, Berris, Mutis, Tuna, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M., and van de Donk, Niels W.C.J.

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results