220 results on '"Musumeci, Francesca"'
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2. Inhibition of serum- and glucocorticoid-induced kinase 1 ameliorates hydrocephalus in preclinical models
3. Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment
4. Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective
5. Unlocking Potential and Limits of Kinase Inhibitors: The Highway to Enhanced Cancer Targeted Therapy
6. Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling
7. Exploring a New Generation of Pyrimidine and Pyridine Derivatives as Anti-Influenza Agents Targeting the Polymerase PA–PB1 Subunits Interaction.
8. Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment
9. Small Molecule Tyrosine Kinase Inhibitors (TKIs) for Glioblastoma Treatment
10. Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines
11. In Preclinical Model of Ovarian Cancer, the SGK1 Inhibitor SI113 Counteracts the Development of Paclitaxel Resistance and Restores Drug Sensitivity
12. New Insights into the LANCL2-ABA Binding Mode towards the Evaluation of New LANCL Agonists
13. Sweet Cherry Extract as Permeation Enhancer of Tyrosine Kinase Inhibitors: A Promising Prospective for Future Oral Anticancer Therapies
14. Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction
15. Identification and Biological Characterization of the Pyrazolo[3,4-d]pyrimidine Derivative SI388 Active as Src Inhibitor
16. Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma
17. Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors
18. The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells
19. Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
20. CYP-dependent Metabolism of Antitumor Pyrazolo[3,4-d]pyrimidine Derivatives Is Characterized by an Oxidative Dechlorination Reaction
21. Identification and Biological Characterization of the Pyrazolo[3,4- d ]pyrimidine Derivative SI388 Active as Src Inhibitor.
22. Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells
23. Inhibition of SGK1 ameliorates ventriculomegaly in a genetic rat model via regulation of TRPV4 in the choroid plexus
24. Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d ]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme.
25. Synthetic Heterocyclic Derivatives as Kinase Inhibitors Tested for the Treatment of Neuroblastoma
26. Synthesis of a new series of optimized pyrazolo[3,4‑d]pyrimidines as Src Inhibitors
27. Starch/Poly(glycerol-adipate) Nanocomposites:A Novel Oral Drug Delivery Device
28. Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus Agents
29. An update on dual Src/Abl inhibitors
30. Synthesis and Antibacterial Evaluation of New Pyrazolo[3,4-d]pyrimidines Kinase Inhibitors
31. Development of Pyrazolo[3,4-d]pyrimidine Kinase Inhibitors as Potential Clinical Candidates for Glioblastoma Multiforme
32. Starch/Poly(glycerol-adipate) Nanocomposites: A Novel Oral Drug Delivery Device
33. Formulation Of Pyrazolo[3,4-d]pyrimidines Kinase Inhibitors For The Treatment Of Glioblastoma Multiforme
34. Additional file 2: of The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells
35. Additional file 1: of The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells
36. Additional file 4: of The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells
37. Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
38. An Update on JAK Inhibitors
39. The small molecule SI113 hinders epithelial‐to‐mesenchymal transition and subverts cytoskeletal organization in human cancer cells
40. Recent Studies on Ponatinib in Cancers Other Than Chronic Myeloid Leukemia
41. Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors
42. Water Solubility Enhancement of Pyrazolo[3,4-d]pyrimidine Derivatives via Miniaturized Polymer–Drug Microarrays
43. The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme
44. Matrine in association with FD-2 stimulates F508del-cystic fibrosis transmembrane conductance regulator activity in the presence of corrector VX809
45. Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors
46. Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors
47. Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model
48. Identification of new pyrrolo[2,3- d ]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma
49. The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the 64CuCl2 in Human Glioblastoma Multiforme Cells
50. SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells
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