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1. An observational, multicenter, registry-based cohort study of Turkish Neonatal Society in neonates with Hypoxic ischemic encephalopathy

Author: Emel Okulu, Ibrahim Murat Hirfanoglu, Mehmet Satar, Omer Erdeve, Esin Koc, Ferda Ozlu, Mahmut Gokce, Didem Armangil, Gaffari Tunc, Nihal Demirel, Sezin Unal, Ramazan Ozdemir, Mehmet Fatih Deveci, Melek Akar, Melike Kefeli Demirel, Merih Çetinkaya, Halime Sema Can Buker, Belma Saygılı Karagöl, Deniz Yaprak, Abdullah Barıs Akcan, Ayse Anik, Fatma Narter, Sema Arayici, Egemen Yildirim, Ilke Mungan Akin, Ozlem Sahin, Ozgul Emel Bulut Ozdemir, Fahri Ovali, Mustafa Ali Akin, Yalcin Celik, Aysen Orman, Sinan Uslu, Hilal Ozkan, Nilgun Koksal, Ayhan Tastekin, Mehmet Gunduz, Ayse Engin Arisoy, Resat Gurpinar, Rahmi Ors, Huseyin Altunhan, Ramazan Kececi, Hacer Yapicioglu Yildizdas, Demet Terek, Mehmet Ates, Sebnem Kader, Mehmet Mutlu, Kıymet Çelik, Ebru Yucesoy, Mustafa Kurthan Mert, Selvi Gulasi, Kazım Kucuktasci, Didem Arman, Berna Hekimoglu, Nazlı Dilay Gultekin, Hasan Tolga Celik, Dilek Kahvecioglu, Can Akyildiz, Erdal Taşkın, Nukhet Aladag Ciftdemir, Saime Sundus Uygun, Tugba Barsan Kaya, Arzu Akdag, and Aslan Yilmaz
Subjects: Medicine, Science
Published: 2023

2. Bilateral adrenal hemorrhage with signs of adrenal insufficiency in the first days of life

Author: Selvi Gülaşı, Eren Kale, Ayşe Koç, Emine Akbaş, Bilgin Yüksel, and Mustafa Kurthan Mert
Subjects: abdominal ultrasonography, adrenal hemorrhage, adrenal insufficiency, hormonal therapy, newborn, Medicine (General), R5-920
Abstract: Bilateral adrenal hemorrhage with signs of adrenal insufficiency in the first days of life
Published: 2020

3. Relationship between umbilical cord blood vitamin D levels and thymus size in healthy and term newborns

Author: Selvi Gülaşı, Mustafa Kurthan Mert, Gökhan Söker, and Ümit Çelik
Subjects: newborn, thymus, ultrasonography, vitamin d, yenidoğan, timus, ultrasonografi, Medicine (General), R5-920
Abstract: Purpose: Thymus is a primary lymphoid organ which contains the vitamin D receptor. Vitamin D has an immunological regulatory effect on the adaptive and innate immune system. The aim of this study was to determine the relationship between cord blood 25-hydroxy vitamin D levels and thymus size.Materials and Methods: 149 babies were included in the present study. The cord blood 25-hydroxy vitamin D level was measured. Mothers’ and infants’ features were recorded. Thymus volume were evaluated with ultrasonography. The thymic index and thymus/weight index were calculated. Results: In the case of irregular use or non-use of maternal vitamin D, the likelihood of vitamin D deficiency in the cord blood was higher. No difference was observed between the thymic index measurements and maternal vitamin D use and cord blood vitamin D level.Conclusion: There was no relationship between cord blood vitamin D level and thymus size.
Published: 2019

4. Pentoxyfilline treatment in nosocomial sepsis of preterm infants

Author: Hacer Yapıcıoğlu Yıldızdaş, Mustafa Kurthan Mert, Ferda Özlü, and Mehmet Satar
Subjects: pentoxifylline, premature, sepsis, pentosifilin, Medicine (General), R5-920
Abstract: Purpose: Nosocomial sepsis is the most common acquired infection. Despite appropriate antibiotic treatment, mortality and morbidity of sepsis are still high. We aimed to evaluate the effect of pentoxifylline on prognosis of neonatal nosocomial sepsis in premature infants hospitalized in the neonatal intensive care unit.Materials and Methods: Eighty newborns diagnosed as nosocomial sepsis were included in this study. Forty of them received pentoxifylline treatment in addition to antibiotics, while the other 40 did not receive additional treatment and formed the control group. The sex, mode of delivery, gestational age, birth weight, Apgar scores at the 1st and 5th minutes, surfactant therapy, ventilator therapy and presence of early onset sepsis were compared between the case group and the control.Results: There was no statistical difference between groups according to gestational week, gender, birth weight, mortality, neutrophil count or procalcitonin level at the time of diagnosis. Also, there was not any statistical difference according to duration of hospitalization between the bronchopulmonary dysplasia or necrotizing enterocolitis groups.Conclusion: Pentoxifylline has no significant impact on mortality and morbidity of preterm nosocomial sepsis.
Published: 2019
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5. Targeted neonatal echocardiography in neonatal intensive care unit

Author: Mustafa Kurthan Mert
Subjects: echocardiography, neonate, intensive care, ekokardiografi, yenidoğan, Medicine (General), R5-920
Abstract: Purpose: The aim of the study is determining the frequency of use, and the patient characteristics and indications.Materials and Methods: This retrospective cohort study included all neonates who underwent targeted neonatal echocardiography in the neonatal unit of Adana Şehir Training and Research Hospital between September 2016 and September 2018. All newborns who underwent echocardiography according to clinical findings within 24 months were included in the study. Data including gestational age, birth weight, respiratory support, timing and diagnosis of echocardiography were obtained from the review of clinical notes.Results: A total of 355 echocardiographic evaluations were performed in 186 newborns. The most common indications for targeted echocardiography were patent ductus arteriosus (n = 148, 41.7%) followed by evaluation of myocardial performance and systemic blood flow (n = 99, 27.9%) and pulmonary hypertension (n= 72, 20.3%). The median time of echocardiographic evaluation was postnatal 22 (1-178) hours. More than half (59.7%) of the newborns received respiratory support (continuous positive pressure ventilation (21%), conventional mechanical ventilation (27.4%), and high frequency oscillation ventilation (11.3%).Conclusion: Targeted echocardiography is often used and it can be a useful tool in guiding treatment. Assessment of patent ductus arteriosus, myocardial performance and systemic blood flow are the most common indications for use. Large, well-coordinated prospective studies are needed to confirm its usefulness.
Published: 2019
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6. Sağlıklı term yenidoğanlarda umbilikal kord kanında D vitamini düzeylerinin timus büyüklüğü ile ilişkisi

Author: Selvi GÜLAŞI, Mustafa Kurthan MERT, Gökhan SÖKER, and Ümit ÇELİK
Subjects: newborn, thymus, ultrasonography, vitamin d, yenidoğan, timus, ultrasonografi, Medicine (General), R5-920
Abstract: Amaç: Timus vitamin D reseptörü içeren primer bir lenfoid organdır. D vitamini adaptif ve doğal immün system üzerine düzenleyici etkilere sahiptir. Bu çalışmanın amacı kord kanı 25-hidroksi vitamin D düzeyi ile timus büyüklüğü arasındaki ilişkiyi tanımlamaktır.Gereç ve Yöntem: Çalışmaya 149 bebek alındı. Kord kanı 25-hidroksi vitamin D düzeyleri ölçüldü. Annelerin ve bebeklerin özellikleri kaydedildi. Timus büyüklüğü ultrasonografi ile değerlendirildi. Timik indeks ve timus/ağırlık indeksi hesaplandı.Bulgular: Annenin D vitaminini düzensiz kullanması veya kullanmaması durumunda kord kanında D vitamin eksikliği olasılığını daha yüksekti. Timik indeks ile annenin vitamin kullanımı ve kord kanı D vitamini düzeyi ile timik indeks arasında ilişki saptanmadı.Sonuç: Kord kanı D vitamini düzeyi ile timik indeks arasında ilişki saptanmamıştır.
Published: 2019

7. Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society.

Author: Esin Koc, Nihal Demirel, Ahmet Yagmur Bas, Dilek Ulubas Isik, Ibrahim Murat Hirfanoglu, Turan Tunc, Fatma Nur Sari, Guner Karatekin, Ramazan Ozdemir, Huseyin Altunhan, Merih Cetinkaya, Beyza Ozcan, Servet Ozkiraz, Sebnem Calkavur, Kadir Serafettin Tekgunduz, Ayhan Tastekin, Ferda Ozlu, Banu Mutlu Ozyurt, Ahmet Ozdemir, Bilin Cetinkaya, Yasar Demirelli, Esad Koklu, Ulker Celik, Nuriye Tarakci, Didem Armangil, Emel Okulu, Fatma Narter, Birgul Mutlu, Mustafa Kurthan Mert, Ali Bulbul, Huseyin Selim Asker, Ozgun Uygur, Ilker Sait Uslu, Sabahattin Ertugrul, Cumhur Aydemir, Hasan Tolga Celik, Kazim Kucuktasci, Selda Arslan, Hacer Ergin, Aysegul Zenciroglu, Sadik Yurttutan, Aysen Orman, Oguz Tuncer, Beril Yasa, Betul Acunas, Sahin Takci, Zeynel Gokmen, Hilal Ozkan, Serdar Comert, Nuran Ustun, Mehmet Mutlu, Bilge Tanyeri Bayraktar, Leyla Bilgin, Funda Tuzun, Ozge Aydemir, Tugba Gursoy, Arzu Akdag, Asli Memisoglu, Emrah Can, Demet Terek, Serdar Beken, Ozden Turan, Nilufer Guzoglu, Rahmi Ors, Yusuf Kale, Berna Hekimoglu, Hakan Aylanc, Funda Eroglu, Suzan Sahin, Murat Konak, Dilek Sarici, Ilknur Kilic, and Nilay Hakan
Subjects: Medicine, Science
Abstract: ObjectiveTo investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey.Material and methodsA prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of ≤1500 g were collected for infants who survived.ResultsData from 69 NICUs were obtained. The mean birth weight and gestational age were 1137±245 g and 29±2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers.ConclusionThe present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.
Published: 2019
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8. Comparison of serum albumin level and lactate for predicting preterm morbidities and mortality

Author: Aygül ELATAŞ, Selvi GÜLAŞI, Mustafa Kurthan MERT, Eren KALE ÇEKİNMEZ, and Orkun TOLUNAY
Subjects: General Earth and Planetary Sciences, General Environmental Science
Abstract: Purpose: We aimed to comparison of serum albumin and lactate level for predicting neonatal morbidities and mortality in preterm infants < 32 weeks of gestation. Materials and Methods: The medical records of babies were retrospectively analyzed. Patients were divided into three groups; plasma albumin levels ≤ 2.5 g/dL were defined as Group 1, 2.6-3 g/dL as Group 2 and ≥ 3 g/dL as Group 3. The babies < 28 weeks of gestation were analysed as a subgroup. Results: 300 infants with mean gestational age of 28.7 ± 2.4 weeks and mean birth weights 1240 ± 405 grams were included. In predicting mortality; the sensitivity of the albumin level within the first three days was 74.4% and the specificity was 73.2% (cut-off < 2.9 g/dL), the sensitivity of the lowest albumin level was 90.7% and the specificity was 70.1% (cut-off < 2.65 g/dL), the sensitivity of the lactate level was 67.4% and the specificity was 63.3% (cut off > 3.1 mmol/L). Analysis of < 28 weeks babies; the sensitivity of lowest albumin level was 80% and the specifity was 66.7% (cut-off < 2.45 g/dL) and the sensitivity of the albumin level within the first three days was 74.3% and the specificity was 72.6% (cut-off < 2.8 g/dL), and the sensitivity of lactate was 74.3% and the specifity was 64.2% (cut-off > 3.1mmol/L). Conclusion: Low serum albumin level appears to be more specific and sensitive than lactate in predicting mortality and may be considered to be added to mortality prediction scores.
Published: 2023
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9. The predictive significance of umbilical cord bilirubin and bilirubin/albumin ratio for neonatal jaundice in healthy term newborns

Author: HANDAN ŞAHAN, SELVİ GÜLAŞI, MUSTAFA KURTHAN MERT, and EREN KALE ÇEKİNMEZ
Subjects: General Medicine
Published: 2023
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10. Impact of antenatal corticosteroid exposure on thymus size in premature infants

Author: Şenay Demir, Mustafa Kurthan Mert, Hasan Kilicdag, Tugana Akbas, Deniz Hanta, Gökhan Söker, and Birgin Torer
Subjects: medicine.medical_specialty, Birth weight, Day of life, Untreated group, Gestational Age, Infant, Premature, Diseases, Thymus Gland, Gastroenterology, Ultrasonography, Prenatal, Adrenal Cortex Hormones, Pregnancy, Internal medicine, medicine, Humans, Prospective Studies, Prospective cohort study, business.industry, Infant, Newborn, Infant, Prenatal Care, Infant, Low Birth Weight, Antenatal corticosteroid, Pediatrics, Perinatology and Child Health, Premature Birth, Gestation, Population study, Female, Birth length, business, Infant, Premature
Abstract: Background This study examined the effect of corticosteroids on the thymic index (TI) and the thymus/weight index (TWI) in infants exposed to antenatal corticosteroids (ACS). Methods This prospective study was conducted between August 2014 and October 2018. A thymus ultrasound was performed to assess thymus size on the second day of life. Thymus size was assessed as TI and TWI. Results In total, 167 neonates (≤34 weeks gestation) constituted the study population, including 94 ACS-exposed infants and 73 untreated infants. The treatment group exhibited significantly lower birth weight and significantly shorter birth length than the ACS (−) group. Therefore, TI was smaller in the treatment group than in the untreated group (6.96 ± 4.05 cm3 vs. 5.64 ± 3.39 cm3). The TWI was 3.69 ± 1.8 cm3/kg in the ACS (−) group versus 3.32 ± 1.56 cm3/kg in the ACS (+) group. The median anteroposterior diameter of the right lobe was 1.33 cm (range, 0.45–2.40) in the ACS (−) group compared to 1.15 cm (range, 0.47–2.40) in the ACS (+) group. The median anteroposterior diameter of the left lobe was 1.40 cm (range, 0.43–2.20) in the ACS (−) group and 1.19 cm (range, 0.32–2.36) in the ACS (+) group. The median largest sagittal area was 2.64 cm2 (range, 0.5–5.46) in the ACS (−) group versus 2.20 cm2 (range, 0.55–5.90) in the ACS (+) group. Conclusion We found that TWI was not significantly changed by ACS exposure in premature infants.
Published: 2022
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11. Preterm bebeklerin nozokomiyal sepsisinde pentoksifilin tedavisi

Author: Ferda Özlü, Mehmet Satar, Hacer Yapicioğlu Yildizdaş, and Mustafa Kurthan Mert
Subjects: Gynecology, medicine.medical_specialty, lcsh:R5-920, business.industry, medicine.disease, pentosifilin, premature, Sepsis, sepsis, pentoxifylline, Nosocomial sepsis, medicine, General Earth and Planetary Sciences, business, lcsh:Medicine (General), General Environmental Science
Abstract: Purpose: Nosocomial sepsis is the most common acquired infection. Despite appropriate antibiotic treatment, mortality and morbidity of sepsis are still high. We aimed to evaluate the effect of pentoxifylline on prognosis of neonatal nosocomial sepsis in premature infants hospitalized in the neonatal intensive care unit.Materials and Methods: Eighty newborns diagnosed as nosocomial sepsis were included in this study. Forty of them received pentoxifylline treatment in addition to antibiotics, while the other 40 did not receive additional treatment and formed the control group. The sex, mode of delivery, gestational age, birth weight, Apgar scores at the 1st and 5th minutes, surfactant therapy, ventilator therapy and presence of early onset sepsis were compared between the case group and the control.Results: There was no statistical difference between groups according to gestational week, gender, birth weight, mortality, neutrophil count or procalcitonin level at the time of diagnosis. Also, there was not any statistical difference according to duration of hospitalization between the bronchopulmonary dysplasia or necrotizing enterocolitis groups.Conclusion: Pentoxifylline has no significant impact on mortality and morbidity of preterm nosocomial sepsis.
Published: 2019

12. Yenidoğan yoğun bakım ünitesinde hedefe yönelik neonatal ekokardiografi

Author: Mustafa Kurthan MERT
Subjects: lcsh:R5-920, ekokardiografi, yenidoğan, echocardiography, neonate, lcsh:Medicine (General), intensive care
Abstract: Amaç: Çalışmanın amacı yenidoğan yoğun bakım ünitesinde hedefe yönelik ekokardiografinin kullanım sıklığını, hasta özelliklerini ve endikasyonlarını belirlemektir.Gereç ve Yöntem: Bu retrospektif kohort çalışması, Eylül 2016 ve Eylül 2018 yılları arasında Adana Şehir Eğitim ve Araştırma Hastanesi yenidoğan ünitesinde hedefe yönelik neonatal ekokardiyografi değerlendirilmesi yapılan tüm yenidoğanları içermektedir. Çalışmaya 24 aylık sürede klinik bulgulara göre ekokardiyografi yapılan tüm yenidoğanlar dahil edildi. Gebelik yaşını, doğum ağırlığını, solunum desteğini, ekokardiyografinin zamanlamasını ve tanılarını içeren veriler klinik notların gözden geçirilmesinden elde edilmiştir.Bulgular: Toplam 355 ekokardiografik değerlendirme 186 yenidoğanda yapıldı. Hedefe yönelik ekokardiografi endikasyonlarından en sık olanı patent duktus arteriozus değerlendirmesi (n = 148, %41,7), ardından miyokard performansı ve sistemik kan akımı değerlendirmesi (n = 99, %27,9) ve pulmoner hipertansiyon (n = 72, % 20,3) idi. Medyan ekokardiyografik değerlendirme zamanı postnatal 22 (1-178) saatti. Yenidoğanların yarısından fazlası (%59,7) solunum desteği almaktaydı (sürekli pozitif basınçlı ventilasyon %21, konvansiyonel mekanik ventilasyon %27,4 ve yüksek frekanslı ossilasyon ventilasyonu % 11,3).Sonuç: Hedefe yönelik ekokardiografi, sıklıkla kullanılır ve tedaviyi yönlendirmede faydali bir araç olabilir. Patent Duktus Arteriozus, miyokard performansı ve sistemik kan akımı değerlendirmesi en sık kullanım endikasyonlardır. Yararlılığını doğrulamak için iyi koordine edilmiş büyük prospektif çalışmalara ihtiyaç vardır.
Published: 2019

13. Normal Values of Third Ventricular Width of Preterm Infants

Author: Ayse Selcan Koc and Mustafa Kurthan Mert
Subjects: medicine.medical_specialty, Univariate analysis, Third ventricle, business.industry, Gestational age, Anterior horn, General Medicine, Normal values, Head circumference, medicine.anatomical_structure, Reference values, Internal medicine, medicine, Cardiology, Ultrasonography, business
Abstract: Objective: Although the third ventricle width reference ranges obtained by cranial ultrasonography in term infants are known in the literature but there are no adequate and up to date data regarding the reference ranges of third ventricle width in premature infants. In our study, we aimed to obtain the normal reference values of third ventricle width and the third ventricle related parameters in preterm infants (gestational age
Published: 2019
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14. The effect of different intravenous lipids on free bilirubin levels in premature infants

Author: Abdullah Tuli, Mustafa Kurthan Mert, Mehmet Satar, Mustafa Muhlis Alparslan, Hüseyin Şimşek, Ferda Özlü, and Hacer Yapıcıoğlu Yıldızdaş
Subjects: medicine.medical_specialty, Fat Emulsions, Intravenous, Bilirubin, Medicine (miscellaneous), Fatty Acids, Nonesterified, Serum bilirubin, chemistry.chemical_compound, Fish Oils, Internal medicine, medicine, Humans, Olive Oil, Triglycerides, chemistry.chemical_classification, Nutrition and Dietetics, business.industry, Neurotoxicity, Infant, Newborn, Fatty acid, medicine.disease, Soybean Oil, Endocrinology, Parenteral nutrition, chemistry, Lipid emulsion, lipids (amino acids, peptides, and proteins), Bilirubin levels, business, Infant, Premature
Abstract: BACKGROUND Intravenous lipid emulsions are commonly used as a part of parenteral nutrition in premature infants. The potential bilirubin-displacing effects of high free fatty acid (FFA) levels during lipid infusions are known. Levels of free bilirubin (FB) predict the risk of bilirubin neurotoxicity more accurately than indirect serum bilirubin levels. In the present study, we decided to compare the effect of two different lipid solutions on free bilirubin and free fatty acids levels in premature infants. METHODS Infants were grouped into two groups according to intravenous lipid preparations: Infants in Group 1 received lipid emulsion containing olive oil + soybean oil and Group 2 received containing olive oil + soybean oil + fish oil. The blood samples were gained when lipid intake was 3.5 g/kg/day and FFA and FB levels were analyzed. RESULTS Serum FFA and FB levels were similar in groups (p = 0.26 and 0.69 respectively). There were significant correlation between serum FFA and FB levels in Group 1 (r = 0.74, p
Published: 2021

15. Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Author: Naomi Jane Wright, Andrew J.M. Leather, Niyi Ade-Ajayi, Nick Sevdalis, Justine Davies, Dan Poenaru, Emmanuel Ameh, Adesoji Ademuyiwa, Kokila Lakhoo, Emily Rose Smith, Abdel Douiri, Maria Elstad, Marcus Sim, Cristiana Riboni, Bruno Martinez-Leo, Melika Akhbari, Stephen Tabiri, Ashrarur Mitul, Dayang Anita Abdul Aziz, Camila Fachin, Alliance Niyukuri, Muhammad Arshad, Fowzia Ibrahim, Natalie Moitt, Mohamed Fahmy Doheim, Hannah Thompson, Harmony Ubhi, Isabelle Williams, Sophia Hashim, Godfrey Sama Philipo, Laura Herrera, Aayenah Yunus, Dominique Vervoort, Samuel Parker, Yousra-Imane Benaskeur, Osaid H. Alser, Nana Adofo-Ansong, Ahmad Alhamid, Hosni khairy Salem, Mahmoud Saleh, Safa Abdal Elrais, Sadi Abukhalaf, Patricia Shinondo, Ibrahim Nour, Emrah Aydin, Agota Vaitkiene, Kelly Naranjo, Andile Maqhawe Dube, Sodumisa Ngwenya, Mina A. Yacoub, Henang Kwasau, Gabriella Hyman, Shrouk Mahmoud Elghazaly, Ibrahim Al-Slaibi, Intisar Hisham, Helena Franco, Hana Arbab, Lubna Samad, Aqil Soomro, Muhammad Amjad Chaudhry, Safina Karim, Muhammad Adnan Khan Khattak, Shireen Anne Nah, Doris Mae Dimatatac, Candy SC Choo, Niveshni Maistry, Ashrarur Rahman Mitul, Samiul Hasan, Sabbir Karim, Hina Yousuf, Taimur Qureshi, Ibrahim Rabi Nour, Raed Nael Al-Taher, Osama Abdul Kareem Sarhan, Luis Garcia-Aparicio, Jordi Prat, Eva Blazquez-Gomez, Xavier Tarrado, Martí Iriondo, Paolo Bragagnini, Segundo Rite, Lars Hagander, Emma Svensson, Sheila Owusu, Alhassan Abdul-Mumin, Dominic Bagbio, Vijay Anand Ismavel, Ann Miriam, Shajin T, Marlene Anaya Dominguez, Monica Ivanov, Andreea Madalina Serban, Miliard Derbew, Mahmoud Elfiky, Maricarmen Olivos Perez, Marcia Abrunhosa Matias, Alexis P Arnaud, Ahmed Negida, Sebastian King, Mohamad Rafi Fazli, Nadia Hamidi, Souhem Touabti, Rossana Francisco Chipalavela, Pablo Lobos, Brendan Jones, Damir Ljuhar, Georg Singer, Annelien Cordonnier, Lorena Jáuregui, Zlatan Zvizdic, Janice Wong, Etienne St-Louis, Qiang Shu, Yang Lui, Catalina Correa, Lucie Pos, Elvyn Alcántara, Erick Féliz, Luis Enrique Zea-Salazar, Liza Ali, Matthieu Peycelon, Nzanzu Kipata Anatole, Cherno S. Jallow, Judith Lindert, Dhruv Ghosh, Cathline Freya Adhiwidjaja, Ahmad Khaleghnejad Tabari, Saran Lotfollahzadeh, Haidar Mohammad Mussein, Fabrizio Vatta, Noemi Pasqua, David Kihiko, Hetal Gohil, Ibrahim R. Nour, Muhammed Elhadi, Suad Ahmed Almada, Gilvydas Verkauskas, Toni Risteski, Alejandro Peñarrieta Daher, Oumaima Outani, James Hamill, Taiwo Lawal, Jack Mulu, Benjamin Yapo, Lily Saldaña, Beda Espineda, Krystian Toczewski, Eugene Tuyishime, Isaac Ndayishimiye, Enaam Raboe, Philip Hammond, Gregor Walker, Ivona Djordjevic, Milind Chitnis, Joonhyuk Son, Sanghoon Lee, Muaad Hussien, Sawazen Malik, Enas Musa Ismail, Ampaipan Boonthai, Nesrine Ben Hadj Dahman, Nigel Hall, Fabiola Ruth Castedo Camacho, Helena Sobrero, Marilyn Butler, Aliev Makhmud, Nathan Novotny, Ahmad G. Hammouri, Maisara Al-Rayyes, Bruce Bvulani, Qais Muraveji, Muhammad Yousuf Murzaie, Ajmal Sherzad, Sayed Aman Haidari, Abdul Baqi Monawar, Dr. Ahmad Zia Samadi, Jesh Thiessen, Ntakarutimana Venant, Sonia Inamuco Hospital, Niyonkuru Jérémie, Jean Claude Mbonicura, Butoyi Jean Marie Vianney, Amezene Tadesse, Samuel Negash, Charles A. Roberts, John N. Jabang, Abdoulie Bah, Kajali Camamra, Armandou Correa, Babucarr Sowe, A. Gai, Musa Jaiteh, Kwizera Jean Raymond, Jean Paul Mvukiyehe, Innocent Itangishaka, Emmanuel Kayibanda, Emery Manirambona, Joseph Lule, Ainhoa Costas-Chavarri, Ian Shyaka Gashugi, Albert Ndata, Georges Gasana, Yves Castar Nezerwa, Turatsinze Simeon, Jean De Dieu Muragijimana, Sakina Rashid, David Msuya, Joseph Elisante, Meghna Solanki, Emmanuel Manjira, Jay Lodhia, Mubashir Jusabani, Murad Tarmohamed, Sengua Koipapi, Touabti Souhem, Nabti Sara, Brahimi Sihem, Bouguermouh Dania, Iaiche Achour Toufik, Baghdadi Nour el islam Mounira, Alouani Habiba, Liliana Aragão, Victor Gonçalves, Marcelo Mauricio Lino Urquizo, Maria Florencia Varela, Pedro Mercado, Bonavia Horacio, Andrea Damiani, Carlos Mac, Daniel Putruele, Karen Liljesthrom, Marianela Bernaus, Cesar Jauri, Alejandrina Cripovich, Ezequiel Bianchin, Maria Gabriela Puig, Lorna Andreussi, Susana Iracelay, Dolores Marcos, Carina Herrera, Nelly Palacios, Romina Avile, Belen Serezo, Debora Montoya, Rodrigo Cepeda, Justo Vaquila, Sofficci Veronica, Liliana Pardo, Pelussi Valeria, Lapalma Julio, Aranda Diego Martin, Palazzi Lucio, Comba Gabriel, Depetrini Marianella, José Alfredo Calderón Arancibia, Enrique Huespe, Gabriela Natalia Losa, Elsa Arancibia Gutiérrez, Humberto Scherl, Daniel Emilio Gonzalez, Valentina Baistrocchi, Yanina Silva, Marcelo Galdeano, Pablo Medard, Ines Sueiras, Enrique Romero Manteola, Victor Hugo Defago, Carlos Mieres, Carlos Alberto, Fabio Cornelli, Marcelo Molina, Pablo Ravetta, Celeste Carolina Patiño Gonzalez, Maria Belen Dallegre, Maria Tatiana Szklarz, Marcos Federico Leyba, Nahuel Ignacio Rivarola, Maria Delia Charras, Adriana Morales, Paloma Caseb, Luzia Toselli, Carolina Millán, Maria del Carmen Junes, Oscar Di Siervi, Jose Gilardi, Soledad Simon, Carla Sofia Contreras, Nair Rojas, Lucia Beatriz Arnoletto, Otilia Eva Blain, Mauro Nicolas Bravo, Nancy Sanchez, Luciana Martina Herrera Pesara, Maria Eugenia Moreno, Carlos Ariel Sferco, Umama Huq, Tamanna Ferdousi, Abdullah Al-Mamun, Sadia Sultana, Refoyez Mahmud, Khalid Mahmud, Fatema Sayeed, Alexander Svirsky, Denisse Sempertegui, Amalia Negrete, Araceli Teran, Mariana Sadagurschi, Nusret Popovic, Kenan Karavdic, Emir Milisic, Asmir Jonuzi, Amira Mesic, Sabina Terzic, Nejra Dendusic, Elna Biber, Anesa Sehic, Nada Zvizdic, Emina Letic, Adna Saracevic, Ajla Hamidovic, Nejra Selak, Dzan Horozic, Lamija Hukic, Amila Muhic, Nedim Vanis, Emir Sokolovic, Adnan Sabic, Karin Becker, Elis Novochadlo Klüppel, André Iván Bradley dos Santos Dias, Miguel Angelo Agulham, Cristiano Bischoff, Stella Sabbatini, Rachel Fernandes de Souza, Ana Beatriz Souza Machado, Juliana Werneck Raposo, Maria Lucia da Silva Augusto, Bianca M.R. Martins, Mariana de Souza Santos Ferreira, Darli Fernandes de Oliveira, Carla Silva dos Santos, Fernanda Ribeiro de Fernández y Alcázar, Érika Alves Dutra da Silva, Mariana Furtado, Horácio Tamada, Marília Silva Ferreira dos Santos, Thayná Lopes de Almeida, Susy Oliveira de Andrade, Antonio Cipriano Gurgel do Amaral, Lais Sartori Giovanoni, Kamila de Deus Passos Leles, Eduardo Corrêa Costa, Leticia Feldens, Luciano Ferraz Schopf, José Carlos Soares de Fraga, Felipe Colombo de Holanda, Paola Maria Brolin Santis Isolan, Julia Loyola Ferreira, Carla Luisa Bruxel, Danielle Lopes Teixeira Ferdinando, Fabricio Zottis Barcelos, Natalia Baseggio, Nicole Knorr Brenner, Rafael Trindade Deyl, Carolina Dure, Iuri Nunes Kist, Rafael Bueno Mazzuca, Sarah Bueno Motter, Yna Ramos, Cristine Suzana Trein, Bianca Rezende Rosa, Murilo de Assis Silva, Flavio Augusto Menin, Isabela Cristina Semensato Carloni, Juliana Antinarelli Norberto da Silva, Adriano Luis Gomes, Mariana Girão Tauffer, Paulo César Bassan Gonçalves, Geraldo Magela Nogueira Marques, Eliane Moriya, Carla Labonia, Ana Lucia Carrasco, Karine Furtado Meyer, Luiz Farion-Aguiar, Fernando Amado, Amanda Antunes, Elisângela Silva, Leila Telles, Giovana Almeida, Aluísio Augusto Belmino Gadelha, Flavia de Azevedo Belesa, Acimar Gonçalves da Cunha, Jr, Beatriz Souza Barros, Josiane Bernartt Zanellato, Patricia Guimarães, Karina Ilheu da Silva, Bianca Ribas, Cristina Reuter, Francis Tanise Casado, Mila Torii Correa Leite, Daniela Testoni, Ruth Guinsburg, Simone de Campos Vieira Abib, Edson Khodor Cury, Suely Dornellas do Nascimento, Arthur Almeida Aguiar, Rodrigo Melo Gallindo, Carolina Gonçalves Borges, Yang Liu, Cai Duote, Jinhu Wang, Zhigang Gao, Liang Liang, Wenjuan Luo, Xiaoxia Zhao, Rui Chen, Peng Wang, Yijiang Han, Ting Huang, Hu Donglai, Guo Xiaodong, Chen Junjie, Libin Zhu, Guowei Wu, Xiaozhou Bao, Haijing Li, Junying Lv, Zhongrong Li, Feng Yong, Zhou Chong Gao, Qiang Bai, Weibing Tang, Hua Xie, Jethishka Motee, Jianming Zhu, Gang Wen, Weiwei Ruan, Shungen Li, Lulu Chen, Shungen Huang, Zhibao Lv, Jinjing Lu, Liuming Huang, Mengnan Yu, Wang Dajia, Yu Zuo Bai, Luis Carlos Rincon, Juliana Mancera, Edgar Alzate Gallego, Laura Torres-Canchala, Nathalia Silva Beltrán, Ghordana Osorio Fory, Daniela Castaño Avila, Angelica Maria Forero Ladino, Juanita Gomez, Martha Jaramillo, Otto Morales, Beatriz Sanchez, Nestor Julien Tinoco Guzmán, Sergio Castañeda Espinosa, Osbaldo Prieto Vargas, Lina Maria Pardo, Eliana Toral, Freud Cáceres Aucatoma, Daniel Hinostroza, Santiago Valencia, Vicente Salinas, Enrique Landivar Cino, Gabriela Yulissa Ponce Fajardo, Miguel Astudillo, Virginia Garcia, Guillermo Muñoz, Leonardo Verduga, Ivan Verduga, Ericka Murillo, Elena Bucaram, Marisol Guayelema, Monica Marmol, Janina Sanchez, Carolina Vergara, Adriana Mena, Junior Velaña, Karla Salazar, Sandra Lara, Elena Chiriboga, Julian Silva, Dalia Gad, Doaa Samy, Menan Ahmed Elsadek, Hanan Mahmoud Mohammed, Mohamed Abouheba, Karim Osamy Ali, Hayssam Rashwan, Omar Moustafa Fawzy, Tarek mohamed Kamel, Rawan Nemer, Mohamed Abada Hassan, Eyad Hassan Falah, Dina Sobhy Abdelhady, Mostafa Zain, Eman Abouzeid Abouzeid Ibrahim, Omar Ossama Elsiraffy, Ahmed Aboelela, Eman mohamed Farag, Ahmed Mohamed Oshiba, Omar Sameh Emam, Alaa Mobarak Attia, Moustafa A. Laymouna, Islam Abdelmonem Ghorab, Mansour Mkayed Mohammed, Nourhan Akram Soliman, Khaled Abd elrahman Ghaly, Kareem Sadek, Mohamed Elsherbiny, Amr Saleh, Hesham Sheir, Tamer Wafa, Mohamed Abd Elmenam, Sherif Abdelmaksoud, Ahmed Reda, Islam Mansour, Mohamed Elzohiri, Basma Waseem, Mohamed Elewaily, Mohammed El-Ghazaly, Ahmad Elhattab, Amr Shalaby, Adham Elsaied, Ahmad Adawy, Mirna Sadek, Mahmoud Abdelfattah Ahmed, Mohamed Omar Herdan, Gena Mohamed Hamed Elassall, Azhar Arabi Mohammed, Mohammed Hamada Takrouney, Tarek Mohamed Essa, Ahmed Mokhtar Mahmoud, Alshaimaa M. Saad, Mariam Albatoul Nageh Fouly, Mahmoud abdelshakour Ibrahim, Mohammad Nageh, Mahmoud M. Saad, Helmy Badr, Mohamed Fayez Fouda, Ahmed Hassan Nofal, Hisham Almohamady, Mohamed Ahmed Arafa, Mohamed Amad, Mohamed Awad Mansour, Jennifer O'Connor, Zachary O'Connor, Nzanzu Anatole, Elysé Nkunzimana, Solomon Machemedze, Lemfuka Dieudonné, William Appeadu-Mensah, Theophilus Teddy Kojo Anyomih, Priscilla Alhassan, Francis A. Abantanga, Vishal Michael, Roshine Mary Koshy, Ankit Raj, Vijay Kumar, Sundeep PT, P Santosh Prabhu, Armin Vosoughi, Ali Farooq Al-Mayoof, Muhamed Jassim Fadhle, Ali Egab Joda, Hayder Nadhim Obaid Algabri, Sultan S. Abdelhamid, Hashem M. Al-Momani, Marzouq Amarin, Louay Y. Zaghlol, Nijmeh Nasser Alsaadi, Yasmeen Z. Qwaider, Hibah Qutishat, Ahmad Hasan Aliwisat, Esraa Arabiat, Isam Bsisu, Raghad M. Murshidi, Mohammad S. Jabaiti, Ziad A. Bataineh, Husam Aldean Abuhayyeh, Thekraiat M. Al Quran, Faris J. Abu Za'nouneh, Mohanad Mutasem Alebbini, Hamzah Abullah Qudah, Omar Ghazi Hussein, Amir M.I. Murad, Justin Z. Amarin, Haya H. Suradi, Sayel H. Alzraikat, Rand Y. Omari, Bashar M. Matour, Layana Al-Halbouni, Rajai O. Zurikat, Ahmad H. Yanis, Sara Al Hussein, Ali Shoubaki, Waleed H. Ghanem, Kuria David, Soita Wycliffe Chitiavi, Moraa Mose, Robert Mugo, James Ndungu, Timothy Mwai, Swaleh Shahbal, Janan Malik, Nirav Chauhan, Francisa Syovata, Kevin Ochieng, Polycarp Omendo Liyenzero, Syeda Ra'ana Hussain, Stanley Mugambi, Roseline Ochieng, Ebtesam Othman Abdulsalam Elkhazmi, Ala Khaled, Aya Albozidi, Manal Ben Enbaya, Mala Elgammudi, Enas Soula, Wegden ibrahim almabrouk Khalel, Yasmine Ali Elhajjaji, Nouriyah Ali Alwaggaa, Sumayyah Ghayth, Dafer abdulhakim .S. Zreeg, Sara Abobaker Tantush, Fatma Bibas, Tesneem Layas, Randa Alamen M Sharif, Wesal Omar F. Saied Aljadidi, Ahmed Tarek, Hazem Ahmed, Kamila Almabrouk Mohammed Essamilghi, Mabroka Alfoghi, Ma'aly A. Abuhlega, Saddam Arrmali, Fatima Mousa Abduljawad, Hasan Mustafa Alosta, Abdulsalam Abuajaila, Fakereldeen Abdelmutalib, Fatma Bashir, Inas Almengar, Mohammad hasan Annajjar, Abdelaziz Deyab, Fathi Elzowawi, Yousef Krayem, Weam Drah, Asma Meftah, Abobaker Mohammed, Lina Ali Arrmalli, Hajir Aljaboo, Abdallah Elayeb, Mohamed Altomi, Ahmed Altaweel, Mohamed Tumi, Hana Milad Bazozi, Aisha Shaklawoon, Mohammed Meftah Alglaib, Abdullahn Abdousalam Elkaloush, Sara Trainba, Hisham Swessi, Ali Alnaeri, Aya Essam Shnishah, Hamassat Mustufa, Sondas Ali Gargum, Sara Ali Tarniba, Hawa Ahmed Shalluf, Hajer Ali Shokri, Taher L. Sarkaz, Osama Tababa, Ahmed Elhadi, Vesna Cvetanovska Naunova, Laze Jovcheski, Marjan Kamilovski, Aleksandra Gavrilovska-Brzanov, Zarina Abdul Latiff, Siti Farhan Moh Pauzi, Marjmin Osman, Felicia Lim, Ainal Huda Abu Bakar, Azrina SK Zaman, Shareena Ishak, Rufinah Teo, Dr. Tammy Teoh Han Qi, Mohd Yusran Bin Othman, Dato' Dr Zakaria bin Zahari, Zulfitri bin Md Hassan, Cheah Hui Shan, Abhirrami Lechmiannandan, Hafatin Fairos bt Tamaddun, Mohd Fitri Shukri bin Mohamed Adanan, Mohd Yusof bin Abdullah, Wang Junyi, Mohd. Tarmizi Mohd Nor, Wan Ruzaimie Noor, Mohd Razin bin Hassan, Noor Fa'izatul Rahil Ambok Dalek, Hidayah Hayati binti Hashim, Ahmad Zulhisyam bin Zarwawi, V Muthualhagi M Vellusamy, Quah Soong Yuen, Hemasutha a/p Kannessan, Najua binti Ramli, Ahmad Shafiee bin Bujarimin, Jessmine Anntinea, Anthony Dass, Hazlina Mohd. Khalid, Nur Atiqah binti Mohd Hanifah, Keily Wong Yue Jyun, Rahilah binti Abd Razak, Nur Atifah binti Mohd Naim, Siti Nur Aien binti Hamid Hamzah, Cristian R. Zalles Vidal, Eduardo Bracho Blanchet, Roberto Dávila Perez, Emilio Fernandez Portilla, Raúl Villegas Silva, Daniel Ibarra, Antonio Calderon Moore, Cesar Carrasco-Ortega, Monica Noguez Castillo, Dorihela Herappe Mellado, Guillermo Yanowsky Reyes, Luis Fernando Gonzalez Cortez, Rafael Santana Ortiz, Jamie Orozco Perez, Jorge Román Corona C.Rivera, Juan Jose Cardenas Ruiz Velasco, Moises Quiles Corona, Christian Peña Padilla, Lucina Bobadilla Morales, Alfredo Corona Rivera, Izabel Maryalexandra Rios Flores, Cristian Irela Aranda Sánchez, Gabriela Ambriz-González, Nestor Martínez Hernández Magro, Francisco Javier León Frutos, José de Jesús Cárdenas Barón, Alejandro González Ojeda, Jessica Yarza Fernández, Juan Domingo Porras, Pastor Aguirre-Lopez, Vicente Sánchez Paredes, Arturo Montalvo Marin, Jose Manuel Diaz Gomez, Lorenzo Juvencio Caamal, David Bulnes Mendizabal, Pablo Sanchez Valladares, Humberto Garcia Martinez, Opeoluwa Adesanya, Moses Olanrewaju, Rilwan Adegboyega, Nurudeen Abdulraheem, Anuoluwapo Aremo, Florence Dedeke, Anyanwu Lofty-John Chukwuemeka, Mohammad Aminu Mohammad, Abdullahi Lawalbarau, Nwokoro Collins, Ogundele Ibukunolu, Amo Shonubi, Oluwaseun Ladipo-Ajayi, Olumide Abiodun Elebute, Justina Seyi-Olajide, Felix Alakaloko, George Ihediwa, Kayode Olayade, Christopher Bode, Olakayode Ogundoyin, Dare I. Olulana, Ifeanyichukwu Kelvin Egbuchulem, Felix O. Kumolalo, Ikechukwu Ulasi, Uchechukwu Obiora Ezomike, Sebastian Okwuchukwu Ekenze, Elochukwu Perpetua Nwankwo, Emmanuel Ifeanyi Nwangwu, Isaac Chukwu, Christopher Chim Amah, Nene Elsie Obianyo, Omolara Williams, Roland Iheanyichukwu Osuoji, Omolara Moronkeji Faboya, Olalekan Temitope Ajai, Moruf Adekunle Abdulsalam, Titiloye Hannah Agboola, Bolarinwa Bolanle Temilade, Maryrose Osazuwa, Morayo Monsurat Salawu, Eze Chukwuemeka Ejinkeonye, Mariya Mukhtar Yola, Amsa B. Mairami, Adekunle T. Otuneye, Matthias Igoche, Adebayo Gbenga Tanimola, Emmanuel Akinlabi Ajao, Efeturi Agelebe, Samson Olori, Philip Mari Mshelbwala, Olabisi Osagie, Adewale Oyinloye, Auwal M Abubakar, Lateef Oyebanji, Ibrahim Shehu, Cyril Cletus, Ahmed Bamanga, Faruk Suleiman, Sani Adamu, David C.Nwosu, Yahya S.Alkali, Iliya Jalo, Aliu Rasaki, Yusuf T.Sambo, Kalakwa A.Mohammed, Abubakar M.Ballah, Victor Modekwe, Okechukwu Hyginus Ekwunife, Ugochukwu S Ezidiegwu, Andrew N Osuigwe, Jideofor O Ugwu, Chuka A Ugwunne, Nadeem Akhter, Mudassir Fayaz Gondal, Rafee Raza, Ali Raza Chaudary, Hassan Ali, Muhammad Umar Nisar, Muhammad Umer Jamal, Ghuri Shankar Pandit, Uzma Mumtaz, Muhammad Bin Amjad, Nabila Talat, Wajeeh ur Rehman, Muhammad Saleem, Muhammad Bilal Mirza, Imran Hashim, Naveed Haider, Soban Hameed, Ayesha Saleem, Sohail Dogar, Muhammad Sharif, Muhammad Kashif Bashir, Fatima Naumeri, Zarqa Rani, Muath A.M. Baniowda, Basheer Ba'baa', Majd Yousef Mohammed Hassan, Ammar Darwish, Abrar Shaheen Sehwiel, Mohammed Shehada, Abrar ghassan Balousha, Yara Ajrami, Ainaa Ata Mohammad Alzamari, Bashar Yaghi, Hasan Subhi Hasan Abu Al-saleem, Mervat Sufian Abu Farha, Mohammad Omar Mohammad Abdelhafez, Firas Anaya, Asef belal Qadomi, Abd Al-Naser Bany Odi, Muath Abdelrahem Fuad Assi, Fadwa Sharabati, Ahmad Abueideh, Doha mustafa saleh Beshtawi, Hasan Arafat, Lara Zahi Adel Khatatba, Safa' Jamal Abatli, Hiba Al-Tammam, Dania Jaber, Yara Imad Omar Kayed, Ali Abdelhay Abumunshar, Rami Anwar Misk, Asmahan Mohammad Suliman Alzeer, Mutassem Sharabati, Ihsan Ghazzawi, Osama Majed Darras, Mahmoud M.Qabaja, Ma'alem sameer Hajajreh, Yasmeen Ahmad Samarah, Dua Hasan Yaghi, Moradallah Asad Fahmi Qunaibi, Abdelrazzaq Abu Mayaleh, Sharehan Joubeh, Annan Ebeido, Samer Adawi, Ihda Adawi, Mohammad Omar Ibrahim Alqor, Ahmad Samih Arar, Hadeel Awad, Fawzi Abu-Nejmah, Osaid Shaher Shabana, Firas Alqarajeh, Tareq Z. Alzughayyar, Jomana Madieh, Mahmoud Fuad Sbaih, Raghad mohammad abdu Alkareem, Raghad abdullateef Lahlooh, Yasmeen Adly Halabi, Wisam Baker, Tasneem Fathi Hasan Almusleh, Abdulraheem Adnan Abdulraheem Tahyneh, Yazid yousef mahmoud Atatri, Najlaa Abu Jamie, Nasrallah Ashraf Al Massry, Walaa Lubbad, Ayoub A.Nemer, Mohammed Alser, Aya Azmi Shehda Salha, Khaled Alnahhal, Aya Mahmoud Elmzyyen, Amir Talat Sheda Ghabayen, Abdulwhhab Ayman Abu Alamrain, Samar H. Al-Shwaikh, Omar Adly Elshaer, Nureddin Shaheen, Jehad Fares, Hisham Dalloul, Anas Qawwash, Mustafa abu Jayyab, Dina Ayman Ashour, Ahmad Ashraf Shaheen, Samy Rafat Ramadan Naim, Eman Abu Shiha, Nagham Mohammed Al Dammagh, Walaa Almadhoun, Ashraf Ayman Al-Salhi, Abdalkarim Yhya Hammato, Jamal Mohammed Salim, Doaa Khalil Hasanain, Soha Marwan Salem Alwadia, Ismail Nassar, Hala M. Al-Attar, Haya Abdulnasser Ali Alshaikhkhalil, Yasmin Mohammed Khalil Abu Jamie, Yara shareef Ashour, Sharif S. Alijla, Mohamed Anwer El Tallaa, Adham Ashraf Abuattaya, Bisan D.M. Wishah, MOHAMMED A.M. ALDIRAWI, Ahmed S Darwish, Sulaiman T. Alzerei, Nidal Wishah, Sharif Alijla, Isidora Garcia, Marlene Diaz Echegaray, Veronica Raquel Cañapataña Sahuanay, Fernando Trigoso Mori, Jackelyne Alvarado Zelada, Juan Jose Salinas Barreto, Porfirio Rivera Altamirano, Cesar Torres Miranda, Rocio Anicama Elias, Julio Rivera Alvarez, Juan Pedro Vasquez Matos, Fernando Ayque Rosas, Jesmarina Ledesma Peraza, Andrea Gutarra Palomino, Stephany Vega Centen, Victor Casquero, María Rosa Ortiz Argomedo, Francisco Lapouble, Genaro Llap Unchón, Florangel Patricia Delgado Malaga, Luis Ortega Sotelo, Segundo Gamboa Kcomt, Araceli Villalba Villalba, Nancy Rossana Mendoza Leon, Loreley Raquel Cardenas Alva, Maria Susana Loo Neyra, Cathy Lee Alanguia Chipana, Cintya Maria de Jesus Torres Picón, Natalia Huaytalla Quiroz, Danny Dominguez, Carlos Segura Calle, Jenny Arauco, Luis Ormeño Calderón, Ximena Ghilardi Silva, Miriam Daniela Fernandez Wilson, Joan Elizabeth Gutierrez Maldonado, Cesar Diaz Leon, Waldo Berrocal Anaya, Patricia Chavez Galvez, Prince Pamela Aguilar Gargurevich, Flor de Maria Diaz Castañeda, Carmen Guisse, Erika Ramos Paredes, Jose Luis Apaza Leon, Faye Aguilar Aguilar, Raul Ramirez De La Cruz, Lenny Flores Carbajal, Carlos Mendoza Chiroque, Gladys Johana Sulca Cruzado, Natalia Tovar Gutierrez, Jennifer Sotelo Sanchez, Carolina Paz Soldan, Karina Hernández Córdova, Edgar Fernando Delgado Quinteros, Luz Mery Brito Quevedo, Juan Jose Mendoza Oviedo, Angel Samanez Obeso, Patricia Paredes Espinoza, Johann de Guzman, Raisa Yu, Vlad Cosoreanu, Sebastian Ionescu, Aurel Mironescu, Lucian Vida, Adrian Papa, Roxana Verdeata, Bogdan Gavrila, Liviu Muntean, Marija Lukac, Miona Stojanovic, Djordje Toplicic, Milan Slavkovic, Andjelka Slavkovi, Dragoljub Zivanovic, Ana Kostic, Maja Raicevic, Delphine Nkuliza, Daniel Sidler, Corné de Vos, Elmarie vd Merwe, David Tasker, Omar Khamag, Cecilia Rengura, Thozama Siyotula, Uzair Jooma, Dirk von Delft, Marion Arnold, Hansraj Mangray, Shamaman Harilal, Sanele Madziba, Naveen Wijekoon, Tharanga Gamage, Benedict Paul Bright, Alaa Abdulrahman, Ola Ahmed Abdulmjeed Mohammed, Mohammed Salah, Ahmad Elian Abu Ajwa, Mohammed Morjan, Mohammad Mohannad Batal, Vivian Faks, Mohamad Bassel Mouti, Ahmadfateh Assi, Ahmad Al-Mouakeh, Ahmad Sankari Tarabishi, Ziad Aljarad, Aos Alhamid, Jiraporn Khorana, Wannisa Poocharoen, Sirima Liukitithara, Anan Sriniworn, Wasun Nuntasunti, Monawat Ngerncham, Ratiyaporn Phannua, Kanokrat Thaiwatcharamas, Patchareeporn Tanming, Lassaad Sahnoun, Nahla Kchiche, Roua Abdelmoumen, Egemen Eroğlu, Mehmet Ali Ozen, Hatice Sonay Yalçın Cömert, Mustafa İmamoğlu, Haluk Sarıhan, Şebnem Kader, Mehmet Mutlu, Yakup Aslan, Ahmet Beşir, Şükran Geze, Bahanur Çekiç, Ali Yalcinkaya, Kaan Sönmez, Ramazan Karabulut, Zafer Türkyılmaz, Kıvanç Şeref, Merve Altın, Merve Aykut, M.Eren Akan, Melisa Erdem, Ebru Ergenekon, Canan Türkyılmaz, Elif Keleş, Ali Canözer, Aslı Öztürk Yeniay, Elif Eren, İlknur Banlı Cesur, Zerrin Özçelik, Gökmen Kurt, Mustafa Kurthan Mert, Hatice Kaya, Müge Çelik, Suleyman Cuneyt Karakus, Nazile Erturk, Alev Suzen, Nilay Hakan, Fatih Akova, Mehmet Pasaoglu, Shukurali Eshkabilov, Rustam Z. Yuldashev, Dekhkonboev Avazjon Abdunomonovich, Aliev Makhmudjan Muslimovich, Azad Patel, Chisengo Kapihya, Nicholas Ensar, Ramesh M Nataraja, Mithila Sivasubramaniam, Matthew Jones, Warwick Teague, Sharman Tan Tanny, Gordon Thomas, Kiera Roberts, Soundappan Sannappa Venkatraman, Holger Till, Manon Pigeolet, Martine Dassonville, Anas Shikha, Win Sabai Phyu Win, Zahidah Adlynee Haji Ahmad, Léamarie Meloche-Dumas, Louise Caouette-Laberge, Dickens St-Vil, Ann Aspirot, Nelson Piché, Shahrzad Joharifard, Nadia Safa, Jean-Martin Laberge, Sherif Emil, Pramod Puligandla, Kenneth Shaw, Hussein Wissanji, Eileen Duggan, Elena Guadagno, Maria Consuelo Puentes, Paola Osses Leal, Carolina Mendez Benavente, Michal Rygl, Barbora Trojanová, Klára Berková, Tereza Racková, Ladislav Planka, Jan Škvařil, Radek Štichhauer, Shahad Sabti, Alex Macdonald, Nordeen Bouhadiba, Dorothy Kufeji, Caroline Pardy, Simon Mccluney, Alireza Keshtgar, Rebecca Roberts, Hannah Rhodes, Kate Burns, Robin Garrett-Cox, Kat Ford, Hannah Cornwall, Krithi Ravi, Felicity Arthur, Paul Losty, Tony Lander, Ingo Jester, Suren Arul, Oliver Gee, Giampiero Soccorso, Michael Singh, Max Pachl, Benjamin Martin, Afnan Alzubair, Arun Kelay, Jonathan Sutcliffe, Thomas Middleton, Amy Hughes Thomas, Merina Kurian, Fraser Cameron, Jayaram Sivaraj, Mark C Thomas, Dean Rex, Ceri Jones, Kate Bradshaw, Arnaud Bonnard, Xavier Delforge, Camille Duchesne, Caroline Le Gall, Coralie Defert, Samia Laraqui Hossini, Florent Guerin, Géraldine Hery, Virginie Fouquet-Languillat, Jules Kohaut, Aline Broch, Thomas Blanc, Luke Harper, Thomas Delefortrie, Quentin Ballouhey, Laurent Fourcade, Céline Grosos, Benoit Parmentier, Guillaume Levard, Maria Giovanna Grella, Mariette Renaux Petel, Lucie Grynberg, Olivier Abbo, Sofia Mouttalib, Mélodie Juricic, Aurelien Scalabre, Elodie Haraux, Anke Rissmann, Hardy Krause, Peter Goebel, Ludwig Patzer, Udo Rolle, Andrea Schmedding, Alexandra Antunez-Mora, Bernd Tillig, Sylvester von Bismarck, Patricia Reis Barbosa, Christian Knorr, Domitille Stark, Marco Brunero, Luigi Avolio, Francesco Manni, Matilde Molinelli, Marinella Guazzotti, Alessandro Raffaele, Piero Giovanni Romano, Silvia Cavaiuolo, Gian Battista Parigi, Laszlo Juhasz, Anna Rieth, Arunas Strumila, Rūta Dagilytė, Arunas Liubsys, Pranas Gurskas, Dalius Malcius, Agne Mikneviciute, Asta Vinskaite, Vidmantas Barauskas, Liam Vierboom, Timothy Hall, Spencer Beasley, Lucy Goddard, Mark Stringer, Naveen Weeratunga, Stephen Adams, Jitoko Cama, Marilyn Wong, Sridharan Jayaratnam, Askar Kukkady, Udaya Samarakkody, Sylwester Gerus, Dariusz Patkowski, Agnieszka Wolny, Tomasz Koszutski, Szymon Tobor, Marta Osowicka, Piotr Czauderna, Dariusz Wyrzykowski, Hanna Garnier, Stefan Anzelewicz, Osowicka Marta, Agata Knurowska, Alicja Weiszewsk, Andrzej Grabowski, Wojciech Korlacki, Michal Pasierbek, Przemyslaw Wolak, Aneta Piotrowska, Anna Roszkiewicz, Piotr Kalicińsk, Agata Trypens, Grzegorz Kowalewsk, David Sigalet, Amer Alsaied, Mansour Ali, Ameen Alsaggaf, Alaa Ghallab, Yazeed Owiwi, Ali Zeinelabdeen, Mohamed Fayez, Ahmed Atta, Mazen Zidan, Asaad saleh Radwan, Hanin Shalaby, Reem Abdelbaqi, Khalid Alattas, Yar Kano, Omar Sindi, Abdullah Alshehri, Tariq Altokhais, Fahad Alturki, Mohammad Almosaibli, Dasha Krisanova, Wisam Abbas, Hee-Beom Yang, Hyun-Young Kim, Joong Kee Youn, Jae Hee Chung, Seok Hyeon Cho, In ji Hwang, Ju yeon Lee, Eung song Song, Jenny Arboleda, Mercedes Ruiz de Temiño Bravo, Alexander Siles Hinojosa, Miriam García, Isabel Casal Beloy, Detlef Oliu San Miguel, Maria Elena Molina Vazquez, Verónica Alonso, Alberto Sanchez, Oscar Gomez, Isabel Carrillo, Tomas Wester, Carmen Mesas Burgos, Martin Salö, Erik Omling, Niclas Rudolfson, Christina Granéli, Helena Arnadóttir, Emma Grottling, Kate Abrahamsson, Vladimir Gatzinsky, Michaela Dellenmark Blom, Daniel Borbonet, Paul Puglia, Vinicio Jimenez Morejon, Gaston Acuna, Mario Moraes, Jonathan Chan, Pavan Brahmamdam, Alan Tom, Karen Sherer, Brandy Gonzales, Aaron Cunningham, Sanjay Krishnaswami, Reto Baertschiger, Mary Leech, Regan Williams, Lauren Camp, Ankush Gosain, Maria Mora, Bailey D. Lyttle, Jeremy Chang, Lydia McColl Makepeace, Kathryn L Fowler, Sara Mansfield, Erica Hodgman, Chukwubinyelum Amaechi, Alana Beres, Mark N. Pernik, Luke J. Dosselman, Murad Almasri, Sunil Jain, Varun Modi, Marianelly Fernandez Ferrer, John Coon, Joann Gonzalez, Medhavi Honhar, Nensi Ruzgar, Griffin Coghill, Sarah Ullrich, Maija Cheung, Katrine Løfberg, Jodie Greenberg, Kate Davenport, Samir Gadepalli, Sarah Fox, Stephanie Johnson, Mercedes Pilkington, April Hamilton, Nicole Lin, Juan Sola, Yang Yao, Jenna Kylene Davis, Monica Langer, Jonathan Vacek, Fizan Abdullah, Julie Khlevner, William Middlesworth, Marc Levitt, Hira Ahmad, Sabina M Siddiqui, Alex Bowder, Terry Derks, Afua Amoabin Amoabin, Brooke Pinar, Frank Owusu-Sekyere, Benmanseur Saousen, Rasika Naidoo, Azra Karamustafic, Danielle Paula de Oliveira, Jerhy Andrade, Antonín Šafus, Jason Langley, Alexandra Wilke, Corazone Deya, Habib Mansour Murtadi, Mindaugas Berzanskis, Nwachukwu Calistus, Olalekan S. Ajiboye, Michael Felix, Osagie O Olabisi, Seçil Erçin, Teymursha Muradi, Stephen S. Burks, Sergio Lerma, Jillian Jacobson, Calin Calancea, Rafael Valerio-Vazquez, Guigui Sikwete, Owusu Sekyere, Akhona Mbonisweni, Shahnoor Syed, Cho Seok Hyeon, Fatemeh Pajouhandeh, Sheba Mary Pognaa Kunfah, Global PaedSurg Research Collaboration, and Tıp Fakültesi
Subjects: Male, Pediatrics, medicine.medical_specialty, Adolescent, Gastrointestinal Diseases, Psychological intervention, Disease, Global Health, Specialties, Surgical, Congenital Abnormalities, Cohort Studies, medicine, Humans, Prospective Studies, Prospective cohort study, Child, Developing Countries, business.industry, Gastroschisis, Developed Countries, Intestinal atresia, Infant, Newborn, Gestational age, Congenital diaphragmatic hernia, Infant, Articles, General Medicine, medicine.disease, Gastrointestinal Tract, Atresia, Child, Preschool, Female, business
Abstract: Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p
Published: 2020

16. Evaluation of the efficacy and safety of levetiracetam treatment for neonatal seizures in extremely preterm infants

Author: Mustafa Kurthan Mert and Leman Tekin Orgun
Subjects: Medicine (General), Pediatrics, medicine.medical_specialty, RD1-811, business.industry, levetiracetam, Extremely preterm, neonatal seizures, Gestational age, Retrospective cohort study, Response to treatment, neonatal nöbetler, R5-920, levetirasetam, Seizure control, Medicine, Gestation, Surgery, Levetiracetam, preterm, business, Neonatal seizure, medicine.drug
Abstract: Aim: Levetiracetam (LEV) is increasingly being used to treat seizures in the neonatal period. Data about using LEV in extremely preterm infants with seizures is insufficient and limited with only a handful studies. This study aimed to evaluate the efficacy and safety of LEV in the treatment of seizures in extremely preterm infants. Methods: This retrospective cohort study was conducted on extremely premature newborns, those who were born ≤28 weeks of gestational age, and took their first intravenous dose of levetiracetam due to neonatal seizure before their 44th gestational week between September 2017-February 2019. Loading and maintenance dosage of LEV, previously used antiepileptic medications, response to treatment and side effects of LEV were recorded. Results: Twenty extremely preterm neonates (9 males and 11 females) who received LEV were evaluated. Gestational ages ranged from 23 to 28 weeks, with a median of 26.5 weeks. Birth weights ranged from 520-1210 gr and 15 infants (75%) had extremely low birth weights. For the treatment of seizures, 12 patients (60 %) were initially started on levetiracetam as first-line therapy and eight patients (40%) were administered levetiracetam as a second or third-line antiepileptic drug. The efficiency of seizure control with LEV was 60 % (12/20) in all patients. The median LEV dose at the time seizure control was achieved was 40 mg/kg. No side effects were observed due to LEV treatment. Conclusion: This study shows that LEV can be efficient and safe for seizure management in extremely preterm infants. Seizure control was better achieved when LEV was given as the first-line antiepileptic medication in extremely preterm infants.
Published: 2020
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17. Does the timing of surgery affect short-term prognosis in newborn infants with meningomyelocele?

Author: Mustafa Kurthan Mert and Ali İhsan Ökten
Subjects: Pediatrics, medicine.medical_specialty, business.industry, Medicine, business, Affect (psychology), Term (time)
Abstract: Objective: To investigate the effect of postnatal primary repair surgery time on short-term (first 30 days) prognosis in neonates with meningomyelocele (MMC).Methods: The records of meningomyelocele patients treated at Adana City Training and Research Hospital between June 30, 2015 and August 1, 2019 were retrospectively reviewed. Demographic and clinical characteristics, surgical time, hospitalization and antibiotic duration, complications and associated anomalies were recorded.Results: Data of 41 patients were evaluated. The patients were divided into two groups according to the time of surgery. There were 18 patients in the early surgery (≤3 days) group and 23 patients in the late surgery (>3 days) group. There was no difference between groups in terms of birth weight, gestational week, head circumference, sex and type of delivery (p>0.05). The length of hospitalization was 17.2 ± 8.2 in the early surgery group and 24.8 ± 16.1 in the late surgery group (p>0.05). Antibiotic duration was 11.8 ± 7.6 in the early surgery group and 13.8 ± 10.1 in the late surgery group (p>0.05). There was no difference between the two groups between the average size of the MMC sac (5.4±1.1 vs 6.1±2.3, p>0.05). The number of patients with postoperative complications in early surgery group was 8 (44.4%) and in late surgery group was 7 (30.4%), and the number of patients reoperated in the first 30 days in early surgery group was 5 (27.7%) and in late surgery group was 6 (26.1%). The number of patients requiring ventriculoperitoneal shunt (VPS) was 9 (50%) in the early surgery group and 13 (56.5%) in the late surgery group. Surgical complications minor-major dehiscences, CSF leakage, local infection, meningitis and ventriculitis are not statistically different between the groups (p>0.05).Conclusion: Although postnatal early surgical intervention in MMC positively affects short-term outcomes, short-term prognosis is also determined by the presence of associated anomalies, VPS placement time, and rupture of the sac.
Published: 2020
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18. Early neonatal outcomes of very-low-birthweight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

Author: Hüseyin Selim Asker, Emrah Can, Cumhur Aydemir, Betül Acunaş, Ali Bulbul, Turan Tunc, Kadir Şerafettin Tekgündüz, Hasan Tolga Çelik, Şahin Takcı, Ramazan Ozdemir, Ahmet Ozdemir, Mehmet Mutlu, Ferda Özlü, Yasar Demirelli, Beyza Ozcan, Rahmi Ors, Fatma Nur Sari, Ilknur Kilic, Guner Karatekin, Dilek Ulubas Isik, Banu Mutlu Özyurt, Berna Hekimoğlu, Sabahattin Ertuğrul, Murat Konak, Selda Arslan, Nuriye Tarakci, Ozgun Uygur, Serdar Cömert, Sadık Yurttutan, Kazim Kucuktasci, Emel Okulu, Arzu Akdag, Nilay Hakan, Nilüfer Güzoğlu, Tugba Gursoy, Hakan Aylanç, Şebnem Çalkavur, Asli Memisoglu, Ayşegül Zenciroğlu, Bilin Cetinkaya, Serdar Beken, Ozge Aydemir, Hacer Ergin, Ibrahim Murat Hirfanoglu, Yusuf Kale, Didem Armangil, Suzan Sahin, Bilge Tanyeri Bayraktar, Özden Turan, Huseyin Altunhan, Servet Ozkiraz, İlker Uslu, Nihal Demirel, Funda Eroglu, Zeynel Gokmen, Aysen Orman, Leyla Bilgin, Esin Koç, Beril Yasa, Demet Terek, Funda Tuzun, Esad Koklu, Nuran Üstün, Birgul Mutlu, Ahmet Yagmur Bas, Merih Cetinkaya, Hilal Özkan, Fatma Narter, Mustafa Kurthan Mert, Ayhan Tastekin, Ulker Celik, Dilek Sarici, Oğuz Tuncer, KOÇ E., DEMİREL N., BAŞ A. Y., Isik D. U., HIRFANOĞLU İ. M., Tunc T., Sari F. N., Karatekin G., ÖZDEMİR R., Altunhan H., et al., Ege Üniversitesi, MÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Hakan, Nilay, Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı, Ertuǧrul, Sabahattin, Selçuk Üniversitesi, OMÜ, Gürsoy, Tuğba (ORCID 0000-0002-6084-4067 & YÖK ID 214691), Koç, Esin, Demirel, Nihal, Baş, Ahmet Yağmur, Işık, Dilek Ulubaş, Hirfanoğlu, İbrahim Murat, Tunc, Turan, Sarı, Fatma Nur, Karatekin, Güner, Özdemir, Ramazan, Altunhan, Hüseyin, Çetinkaya, Merih, Özcan, Beyza, Özkiraz, Servet, Çalkavur, Sebnem, Tekgündüz, Kadir Şerafettin, Taştekin, Ayhan, Özlü, Ferda, Özyurt, Banu Mutlu, Özdemir, Ahmet, Çetinkaya, Bilin, Demirelli, Yaşar, Köklü, Esad, Çelik, Ülker, Tarakçı, Nuriye, Armangil, Didem, Okulu, Emel, Narter, Fatma, Mutlu, Birgul, Mert, Mustafa Kurthan, Bülbül, Ali, Asker, Hüseyin Selim, Uygur, ÖzgÜn, Uslu, İlker Sait, Ertuğrul, Sabahattin, Aydemir, Cumhur, Çelik, Hasan Tolga, Küçüktaşçı, Kazım, Arslan, Selda, Ergin, Hacer, Zenciroğlu, Aysegül, Yurttutan, Sadık, Orman, Ayşen, Tuncer, Oğuz, Yaşa, Beril, Acunas, Betül, Takci, Şahin, Gökmen, Zeynel, Özkan, Hilal, Cömert, Serdar, Üstün, Nuran, Mutlu, Mehmet, Bayraktar, Bilge Tanyeri, Bilgin, Leyla, Tuzun, Funda, Aydemir, Özge, Akdağ, Arzu, Memisoğlu, Aslı, Can, Emrah, Terek, Demet, Beken, Serdar, Turan, Özden, Güzoğlu, Nilüfer, Örs, Rahmi, Kale, Yusuf, Hekimoğlu, Berna, Aylanc, Hakan, Eroğlu, Funda, Şahin, Suzan, Konak, Murat, Sarıcı, Dilek, Kılıç, İlknur, School of Medicine, Acibadem University Dspace, KKÜ, and Kırıkkale Üniversitesi
Subjects: Male, Turkey, Temel Bilimler (SCI), very low birth weight, ÇOK DİSİPLİNLİ BİLİMLER, Pathology and Laboratory Medicine, blood culture, Pediatrics, Infant, Newborn, Diseases, lung dysplasia, sepsis, Families, 0302 clinical medicine, newborn, Pregnancy, Birth Weight, Medicine, Prospective Studies, Children, [Anahtar Kelime Yok], Organic Compounds, adult, steroid, Pregnancy Outcome, clinical trial, Retinopathy of prematurity, cohort analysis, Bronchopulmonary dysplasia, Necrotizing enterocolitis, Morbidity, Mortality, Health, Prematurity, Infections, Countries, Distress, Sepsis, Physical Sciences, disease severity, prospective study, survival rate, medicine.medical_specialty, Science, Article, patent ductus arteriosus, 03 medical and health sciences, Signs and Symptoms, turkey (bird), Intensive Care Units, Neonatal, Intensive care, Humans, Retinopathy of Prematurity, human, Retinopathy, necrotizing enterocolitis, MULTIDISCIPLINARY SCIENCES, Chemical Compounds, Biology and Life Sciences, Neonates, Doğa Bilimleri Genel, medicine.disease, major clinical study, neonatal intensive care unit, Health Care, hospital discharge, Ophthalmology, Low birth weight, multicenter study, NATURAL SCIENCES, GENERAL, Population Groupings, Health Statistics, Neonatology, Developmental Biology, genetic structures, morbidity, hemodynamics, Neonatal Care, Turkey (republic), Medicine and Health Sciences, Infant, Very Low Birth Weight, 030212 general & internal medicine, gestational age, Prospective cohort study, Science and technology, Multidisciplinary, Temel Bilimler, Gestational age, newborn disease, Chemistry, female, Natural Sciences (SCI), brain hemorrhage, Retinal Disorders, Steroids, Female, Neonatal Sepsis, newborn morbidity, medicine.symptom, Natural Sciences, Infants, Research Article, Adult, Birth weight, Gestational Age, Turkish Neonatal Society, Diagnostic Medicine, 030225 pediatrics, retinopathy, controlled study, outcome assessment, perinatal period, Multidisipliner, business.industry, Organic Chemistry, prematurity, Infant, Newborn, infant, Age Groups, People and Places, Study, business, Early Neonatal Outcomes
Abstract: Beken, Serdar/0000-0002-8609-2684; BAS, AHMET YAGMUR/0000-0002-1329-2167; Bulbul, Ali/0000-0002-3510-3056; Karatekin, Guner/0000-0001-7112-0323, WOS: 000534242500056, PubMed: 31851725, Objective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 and April 30, 2017. the study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of.1500 g were collected for infants who survived. Results Data from 69 NICUs were obtained. the mean birth weight and gestational age were 1137 +/- 245 g and 29 +/- 2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers. Conclusion the present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs., Turkish Neonatal Society [2-2016]; Turkish Neonatal Society, This study was supported by the Turkish Neonatal Society, http://www.neonatology.org.tr, number 2-2016, received by AYB. Turkish Neonatal Society funded the study's online registry system. the funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Published: 2019

19. Awareness and Attitude Relating to the Human Papilloma Virus and its Vaccines Among Pediatrics, Obstetrics and Gynecology Specialists in Turkey

Author: Tamer Çelik, Mustafa Kurthan Mert, Seyfettin Senih Karaman, Salim Reşitoğlu, Fahri Aydin, Cigdem Donmezer, Hüseyin Başpınar, Orkun Tolunay, Hasan Samsa, Ümit Çelik, and Sefa Arli
Subjects: Adult, Male, Sexually transmitted disease, Health Knowledge, Attitudes, Practice, Cancer Research, Pediatrics, medicine.medical_specialty, Turkey, Attitude of Health Personnel, Epidemiology, Uterine Cervical Neoplasms, Developing country, Obstetrics and gynaecology, Surveys and Questionnaires, Humans, Medicine, Papillomavirus Vaccines, Misinformation, Practice Patterns, Physicians', Human papillomavirus, Papillomaviridae, Neoplasm Staging, business.industry, Papillomavirus Infections, Public Health, Environmental and Occupational Health, HPV infection, virus diseases, Prognosis, medicine.disease, female genital diseases and pregnancy complications, Survival Rate, Vaccination, Oncology, Immunization, Female, business, Follow-Up Studies
Abstract: Background: To determine the level of knowledge on human papillomavirus (HPV) infection and vaccination, and the attitude towards HPV vaccination in pediatricians, obstetricians and gynecologists (OBG). Materials and Methods: Participants were administered a 40-question survey, investigating the demographic properties, the knowledge on the HPV infection-vaccination and attitudes towards vaccination. Results: The study enrolled a total of 228 participants (131 pediatricians and 97 OBGs). At a rate of 99.6%, the participants agreed with the fact that the HPV infection was the most common sexually transmitted disease and 33.8% of the participants had the opinion that the HPV vaccination should be administered only in women. The lowest level of HPV vaccine recommendation was among the pediatrics specialists (59.4%, p=0.012). When asked whether they would have their daughters receive HPV vaccination, 79.5% of the participants answered favorably; this rate was 36.7% for the sons. At a rate of 59.5% of the participants thought that the HPV vaccine needed to be included in the national vaccine schedule. Most of the participants (91.6%) had the idea that reduction of the vaccine costs would increase the vaccination frequency. Conclusions: We observed that the consideration of the costs and the prejudices relating to the inefficacy of vaccination as well as the inadequate level of knowledge were involved in the physicians’ resistance to HPV vaccination. We believe that the healthcare professionals should be informed adequately to overcome false beliefs, thereby ensuring success of the HPV vaccine upon inclusion in the national vaccine schedule in the future.
Published: 2015
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20. Use of ultrasound for central venous catheterization in pediatric intensive care unit; a single center experience

Author: Tamer Çelik, Orkun Tolunay, Mustafa Kurthan Mert, Ümit Çelik, Bozkurt Gülek, and Mehmet Kemal Okuyan
Subjects: Pediatric intensive care unit, medicine.medical_specialty, Venous catheterization, business.industry, Ultrasound, medicine, Intensive care medicine, business, Single Center
Published: 2015
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21. Antibiotic Use in Pediatric and Neonatal Intensive Care Units; Multicenter Point Prevalence Study

Author: Naime Gökay, Orkun Tolunay, Hande Gulcan, Nejat Narli, Kemal Kiraz, İlknur Tolunay, Mustafa Kurthan Mert, Kenan Özcan, Ümit Çelik, Gülperi Yücel, Salim Reşitoğlu, Deniz Hanta, Ulaş Özdemir, Tamer Çelik, Hacer Yapıcıoğlu, and Dincer Yildizdas
Subjects: medicine.medical_specialty, Respiratory tract infections, business.industry, Prevalence, Meropenem, Infectious Diseases, Intensive care, Critical care nursing, Pediatrics, Perinatology and Child Health, Emergency medicine, Public hospital, Pediatric Infectious Disease, medicine, Vancomycin, book.journal, Intensive care medicine, business, book, medicine.drug
Abstract: Objective: Identifying antibiotic use in pediatric and neonatal intensive care units with a point prevalence study in Adana, Turkey’s sixth largest city. Material and Methods: In this point prevalence study, demographic information and antibiotic treatment data were taken on the same day from patients in pediatric and neonatal intensive care units of 6 hospitals located in Adana’s city center. Results: Four pediatric intensive care units (two university, one research and training hospital, and one public hospital) and six neonatal intensive care units (two university, one research and training hospital, one public hospital, and two private hospital) were included in the study; 220 patients were at the intensive care units at the time of the study, 44 (20%) of the patients were in the pediatric intensive care units, and 176 (80%) of them were at the neonatal intensive care units. Also, 146 (66.4%) of the patients were using antibiotics. The frequency of antibiotic use was 72.7% in the pediatric intensive care units and 64.8% in neonatal intensive care units. There was a pediatric infectious disease physician at the university and research and training hospital. Antibiotic usage was lower (p=0.002) in clinics where pediatric infectious disease physician consultations could be done. Double antibiotic combination was applied most frequently. Mostly, ampicillin was preferred at neonatal intensive care units. Clarithromycin was used as a second choice because of seasonal lower respiratory tract infections. Vancomycin was the most preferred antibiotic in pediatric intensive care units, and meropenem and linezolid were the second and third choices. At both intensive care units, use of empiric antibiotic treatment was more frequent. Empiric treatment was applied in 22 (68.7%) patients in the pediatric intensive care units and 95 (83.3%) in neonatal intensive care units. Antibiotics were given to 14.3% of the patients in line with the resulting cultures. Conclusion: Intensive care units are services where antibiotics are used most frequently both in Turkey and in the world. In our opinion, protocols need to be established in clinics, national and international guides should be followed; and pediatric infectious disease physician consultations should be increased in order to reduce the frequency of antibiotic use, inappropriate indications, and inappropriate doses. (J Pediatr Inf 2014; 8: 56-63)
Published: 2014
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22. Troponin T and NT ProBNP Levels in Gestational, Type 1 and Type 2 Diabetic Mothers and Macrosomic Infants

Author: Mustafa Kurthan Mert, Hüseyin Selim Asker, Tamer Tetiker, Eren Kale Çekinmez, Fatma Tuncay Özgünen, Akgün Yaman, Mehmet Satar, Nazan Özbarlas, and Çukurova Üniversitesi
Subjects: Cardiac function curve, Heart Defects, Congenital, Male, medicine.medical_specialty, Pediatrics, Infant of diabetic mother, Mothers, 030204 cardiovascular system & hematology, Umbilical cord, Fetal Macrosomia, 03 medical and health sciences, 0302 clinical medicine, Troponin T, Pregnancy, Internal medicine, Natriuretic Peptide, Brain, Medicine, Birth Weight, Humans, cardiovascular diseases, Interventricular septum, Prospective Studies, 030219 obstetrics & reproductive medicine, business.industry, Infant, Newborn, Fetal Blood, Peptide Fragments, Cardiac surgery, Diabetes, Gestational, medicine.anatomical_structure, Macrosomic infant, Echocardiography, Metabolic control analysis, Pediatrics, Perinatology and Child Health, Cardiology, NT proBNP, Gestation, Arterial blood, Female, Cardiology and Cardiovascular Medicine, business
Abstract: PubMedID: 26266327 This study compares NT proBNP and troponin T levels in umbilical cord arterial blood and postnatal echocardiographic findings for infants of gestational and pregestational diabetic mothers and macrosomic infants. Twenty-seven infants of pregestational diabetic mothers, 61 infants of gestational diabetic mothers and 37 macrosomic infants of nondiabetic mothers were prospectively enrolled in this study along with a control group of 58 healthy infants of mothers without any pregestational or gestational disorders as the control group. All enrollees were born after 34 weeks of gestation. For this study, umbilical cord blood was drawn during delivery to determine NT proBNP and troponin T levels. Echocardiography was performed 24–72 h after the delivery. Umbilical cord troponin T and NT proBNP levels were found to be higher in the diabetic and macrosomic groups than in the control group (all of them p 6.1 %) metabolic control. In the good and suboptimal metabolic control diabetic groups, NT proBNP levels were also positively correlated with interventricular septum thickness (r = 0.536 and r = 0.576, respectively, p
Published: 2015

23. Placento-Cranial Adhesions in Amniotic Band Syndrome and the Role of Surgery in Their Management: An Unusual Case Presentation and Systematic Literature Review

Author: Ali İhsan Ökten, Mustafa Kurthan Mert, Guner Menekse, Burak Olmaz, Tamer Çelik, and Ümit Çelik
Subjects: Adult, Male, medicine.medical_specialty, Placenta, Adhesion (medicine), Tissue Adhesions, Fatal Outcome, Pregnancy, medicine, Acalvaria, Humans, Craniofacial, business.industry, Skull, Infant, Newborn, Disease Management, General Medicine, medicine.disease, Trunk, Surgery, Systematic review, Schizencephaly, Pediatrics, Perinatology and Child Health, Female, Neurology (clinical), Amniotic Band Syndrome, Presentation (obstetrics), business
Abstract: Amniotic band syndrome is a group of sporadic congenital anomalies that involve the limbs, craniofacial regions and trunk, ranging from simple digital band constriction to complex craniofacial and central nervous system abnormalities. Placento-cranial adhesions in amniotic band syndrome are extremely rare, and severe conditions are associated with high morbidity and mortality rates. In this study, we pooled placento-cranial adhesion case reports that were published in the medical literature and added an unpublished case from our institution. The purpose of this article was to review and discuss the clinical features and outcomes of placento-cranial adhesions in amniotic band syndrome.
Published: 2015

24. Çocuk yoğun bakım ve yenidoğan yoğun bakımlarda antibiyotik kullanımı; Çok merkezli nokta prevalans çalışması

Author: Orkun Tolunay, Ümit Çelik, Gülperi Yücel, Tamer Çelik, Mustafa Kurthan Mert, Salim Reşitoğlu, Ulaş Özdemir, Nejat Narlı, Deniz Hanta, Hacer Yapıcıoğlu, Hande Gülcan, Kenan Özcan, Dinçer Yıldızdaş, İlknur Tolunay, Naime Gökay, Kemal Kiraz, and Çukurova Üniversitesi
Subjects: Enfeksiyon Hastalıkları
Abstract: Amaç: Nokta prevalans çalışması ile Türkiye’nin 6. büyük şehri olan Adana’da çocuk yoğun bakım ve yenidoğan yoğun bakımlarda antibiyotik kullanımını saptamak. Gereç ve Yöntemler: Bu nokta prevalans çalışmasın- da Adana şehir merkezinde bulunan 6 hastanede çocuk yoğun bakım ve yenidoğan yoğun bakım ünite- sinde yatmakta olan hastaların aynı gün içerisinde demografik bilgileri ve antibiyotik tedavilerine ait veriler toplandı. Bulgular: Çalışmaya toplam dört çocuk yoğun bakım (iki üniversite, bir eğitim ve araştırma hastanesi, bir devlet hastanesi), altı yenidoğan bakım ünitesi (iki üni- versite, bir eğitim ve araştırma hastanesi, bir devlet hastanesi, iki özel hastane) alındı. Çalışmanın yapıldığı gün yoğun bakımlarda 220 hasta yatmaktaydı. Hastaların 44’ü (%20) çocuk yoğun bakımlarda, 176’sı (%80) yenidoğan yoğun bakımlarda yatmaktaydı. Hastaların 146’sı (%66,4) antibiyotik kullanmaktaydı. Bu oran çocuk yoğun bakımlarda %72,7, yenidoğan yoğun bakımlarda %64,8 idi. Bir üniversite ve eğitim araştırma hastanesinde çocuk enfeksiyon hastalıkları uzmanı vardı. Çocuk enfeksiyon hastalıkları konsültas- yonu yapılabilen kliniklerde antibiyotik kullanma oranı daha düşüktü (p=0,002). En sık ikili antibiyotik kombi- nasyonu tercih edilmişti. Yenidoğan yoğun bakımlarda en sık ampisilin tercih edilirken ikinci sıklıkta dönemsel solunum yolu enfeksiyonlarına bağlı olarak klaritromisin tercih edilmişti. Çocuk yoğun bakımlarda vankomisin en sık tercih edi- len antibiyotik iken, ikinci sıklıkta meropenem ve linezolid gelmek- teydi. Her iki yoğun bakımda da ampirik antibiyotik verilme sıklığı daha fazlaydı, çocuk yoğun bakımlarda 22 (%68,7) hastaya, yenidoğan yoğun bakımlarda 95 (%83,3) hastaya ampirik tedavi verilmekteydi. Hastaların %14,3’üne o an için sonuçlanmış kültür- lere göre antibiyotik verilmekteydi. Sonuç: Yoğun bakımlar dünyada ve Türkiye’de antibiyotik kulla- nım oranları en yüksek olan servislerdir. Uygun olmayan endikas- yon, doz ve sıklıkta antibiyotik kullanımının azaltılması için klinik- lerin belirli protokoller oluşturması, ulusal-uluslararası kılavuzları takip etmeleri, çocuk enfeksiyon hastalıkları uzmanı konsültas- yonlarının artmasını sağlamalarının uygun olacağı kanaatindeyiz. (J Pediatr Inf 2014; 8: 56-63) Objective: Identifying antibiotic use in pediatric and neonatal intensive care units with a point prevalence study in Adana, Turkey’s sixth largest city. Material and Methods: In this point prevalence study, demographic information and antibiotic treat- ment data were taken on the same day from patients in pediatric and neonatal intensive care units of 6 hos- pitals located in Adana’s city center. Results: Four pediatric intensive care units (two uni- versity, one research and training hospital, and one public hospital) and six neonatal intensive care units (two university, one research and training hospital, one public hospital, and two private hospital) were included in the study; 220 patients were at the inten- sive care units at the time of the study-44 (20%) of the patients were in the pediatric intensive care units, and 176 (80%) of them were at the neonatal intensive care units. Also, 146 (66.4%) of the patients were using antibiotics. The frequency of antibiotic use was 72.7% in the pediatric intensive care units and 64.8% in neonatal intensive care units. There was a pediatric infectious disease physician at the university and research and training hospital. Antibiotic usage was lower (p=0.002) in clinics where pediatric infectious disease physician consultations could be done. Dual antibiotic combination was applied most frequently. Mostly, ampicillin was preferred at neonatal intensive care units. Clarithromycin was used as a second choice because of seasonal lower respiratory tract infections. Vancomycin was the most preferred antibiotic in pediatric intensive care units, and meropenem and linezolid were the second and third choices. At both intensive care units, use of empiric antibiotic treatment was more frequent. Empiric treat- ment was applied in 22 (68.7%) patients in the pediatric inten- sive care units and 95 (83.3%) in neonatal intensive care units. Antibiotics were given to 14.3% of the patients in line with the resulting cultures. Conclusion: Intensive care units are services where antibiotics are used most frequently both in Turkey and in the world. In our opinion, protocols need to be established in clinics, national and international guides should be followed; and pediatric infectious disease physician consultations should be increased in order to reduce the frequency of antibiotic use, inappropriate indications, and inappropriate doses.
Published: 2014

25. Factors affecting epilepsy development and epilepsy prognosis in cerebral palsy

Author: Şakir Altunbaşak, Mustafa Kurthan Mert, Nurcihan Kiriş, Faruk Incecik, Gülen Gül Mert, Ozlem M Herguner, İlker Ünal, and Çukurova Üniversitesi
Subjects: Male, medicine.medical_specialty, Pediatrics, Adolescent, Electroencephalography, Logistic regression, Cerebral palsy, Epilepsy, Developmental Neuroscience, medicine, Humans, Ictal, Family history, Neonatal seizure, Child, Univariate analysis, medicine.diagnostic_test, Cerebral Palsy, Age Factors, medicine.disease, Prognosis, Neurology, Child, Preschool, Pediatrics, Perinatology and Child Health, Physical therapy, Female, Neurology (clinical), Psychology
Abstract: PubMedID: 21763948 A study was conducted between November 2006 and October 2009 to determine the factors predicting the presence and prognosis of epilepsy in patients with cerebral palsy. We enrolled 2 groups of patients: 42 with cerebral palsy in group 1 and 56 patients with cerebral palsy and epilepsy in group 2. The subjects in group 2 were considered to have good epilepsy prognosis if they were free of seizures for the previous year; otherwise they were considered to have poor epilepsy prognosis. In group 2, neonatal epilepsy, family history of epilepsy, and moderate to severe mental retardation were significantly higher than in group 1 (P < 0.05). In univariate analysis, neonatal seizures, epileptic activity as measured by electroencephalography, and polytherapy were found to be predictors of poor epilepsy prognosis. Additionally, the need for long-term medication to control seizures unfavorably affects prognosis. In logistic regression analysis, neonatal seizure and interictal epileptic activity in electroencephalography were found to be independent predictors of poor epilepsy outcome. In addition, logistic regression analysis revealed that increasing age reduces the success of epilepsy treatment. Neonatal seizures, family history of epilepsy, and mental retardation were found to be important and independent predictors of development of epilepsy in patients with cerebral palsy. © 2011 Elsevier Inc. All rights reserved.
Published: 2010

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25 results on '"Mustafa Kurthan Mert"'

1. An observational, multicenter, registry-based cohort study of Turkish Neonatal Society in neonates with Hypoxic ischemic encephalopathy

2. Bilateral adrenal hemorrhage with signs of adrenal insufficiency in the first days of life

3. Relationship between umbilical cord blood vitamin D levels and thymus size in healthy and term newborns

4. Pentoxyfilline treatment in nosocomial sepsis of preterm infants

5. Targeted neonatal echocardiography in neonatal intensive care unit

6. Sağlıklı term yenidoğanlarda umbilikal kord kanında D vitamini düzeylerinin timus büyüklüğü ile ilişkisi

7. Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society.

8. Comparison of serum albumin level and lactate for predicting preterm morbidities and mortality

9. The predictive significance of umbilical cord bilirubin and bilirubin/albumin ratio for neonatal jaundice in healthy term newborns

10. Impact of antenatal corticosteroid exposure on thymus size in premature infants

11. Preterm bebeklerin nozokomiyal sepsisinde pentoksifilin tedavisi

12. Yenidoğan yoğun bakım ünitesinde hedefe yönelik neonatal ekokardiografi

13. Normal Values of Third Ventricular Width of Preterm Infants

14. The effect of different intravenous lipids on free bilirubin levels in premature infants

15. Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

16. Evaluation of the efficacy and safety of levetiracetam treatment for neonatal seizures in extremely preterm infants

17. Does the timing of surgery affect short-term prognosis in newborn infants with meningomyelocele?

18. Early neonatal outcomes of very-low-birthweight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

19. Awareness and Attitude Relating to the Human Papilloma Virus and its Vaccines Among Pediatrics, Obstetrics and Gynecology Specialists in Turkey

20. Use of ultrasound for central venous catheterization in pediatric intensive care unit; a single center experience

21. Antibiotic Use in Pediatric and Neonatal Intensive Care Units; Multicenter Point Prevalence Study

22. Troponin T and NT ProBNP Levels in Gestational, Type 1 and Type 2 Diabetic Mothers and Macrosomic Infants

23. Placento-Cranial Adhesions in Amniotic Band Syndrome and the Role of Surgery in Their Management: An Unusual Case Presentation and Systematic Literature Review

24. Çocuk yoğun bakım ve yenidoğan yoğun bakımlarda antibiyotik kullanımı; Çok merkezli nokta prevalans çalışması

25. Factors affecting epilepsy development and epilepsy prognosis in cerebral palsy

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