6 results on '"Mustafa EBİK"'
Search Results
2. Double Coronary-Cameral Fistula Draining to the Right Ventricle in a Patient with Mitral Stenosis: is it Clinically Relevant?
- Author
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Mustafa Ebik, Cihan Öztürk, and Fethi Emre Ustabaşıoğlu
- Subjects
Medicine - Published
- 2023
- Full Text
- View/download PDF
3. The Effect of Thyroid Stimulating Hormone Level Within the Reference Range on In-Hospital and Short-Term Prognosis in Acute Coronary Syndrome Patients
- Author
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Muhammet Gürdoğan, Servet Altay, Selçuk Korkmaz, Çağlar Kaya, Utku Zeybey, Mustafa Ebik, and Melik Demir
- Subjects
acute coronary syndrome ,thyroid-stimulating hormone ,mortality ,prognosis ,Medicine (General) ,R5-920 - Abstract
Background and objectives: Despite being within the normal reference range, changes in thyroid stimulating hormone (TSH) levels have negative effects on the cardiovascular system. The majority of patients admitted to hospital with acute coronary syndrome (ACS) are euthyroid. The aim of this study was to investigate the effect of TSH level on the prognosis of in-hospital and follow-up periods of euthyroid ACS patients. Materials and Methods: A total of 629 patients with acute coronary syndrome without thyroid dysfunction were included in the study. TSH levels of patients were 0.3–5.33 uIU/mL. Patients were divided into three TSH tertiles: TSH level between (1) 0.3 uIU/mL and n = 209), (2) 0.90 uIU/mL and n = 210), and (3) 1.60 uIU/mL and 5.33 uIU/mL (n = 210). Demographic, clinical laboratory, and angiographic characteristics were compared between groups in terms of in-hospital and follow-up prognosis. Results: Mean age was 63.42 ± 12.5, and 73.9% were male. There was significant difference between tertiles in terms of TSH level at admission (p < 0.001), the severity of coronary artery disease (p = 0.024), in-hospital mortality (p < 0.001), in-hospital major hemorrhage (p = 0.005), total adverse clinical event (p = 0.03), follow-up mortality (p = 0.022), and total mortality (p < 0.001). In multivariate logistic regression analysis, the high–normal TSH tertile was found to be cumulative mortality increasing factor (OR = 6.307, 95%; CI: 1.769–22.480; p = 0.005) during the 6-month follow-up period after hospitalization and discharge. Conclusions: High–normal TSH tertile during hospital admission in euthyroid ACS patients is an independent predictor of total mortality during the 6-month follow-up period after hospitalization and discharge.
- Published
- 2019
- Full Text
- View/download PDF
4. The etiology and age-related properties of patients with delirium in coronary intensive care unit and its effects on inhospital and follow up prognosis
- Author
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Melik Demir, Utku Zeybey, Servet Altay, Çağlar Kaya, Fatih Kardaş, Burcu Çakır, Muhammet Gürdoğan, and Mustafa Ebik
- Subjects
Male ,medicine.medical_specialty ,behavioral disciplines and activities ,law.invention ,Risk Factors ,law ,Intensive care ,mental disorders ,medicine ,Humans ,Aged ,Aged, 80 and over ,business.industry ,Incidence (epidemiology) ,Mortality rate ,Coronary Care Units ,Age Factors ,Delirium ,Middle Aged ,Prognosis ,medicine.disease ,Intensive care unit ,Comorbidity ,nervous system diseases ,Intensive Care Units ,Neurology ,Emergency medicine ,Etiology ,Female ,Neurology (clinical) ,medicine.symptom ,business ,Follow-Up Studies ,Coronary intensive care - Abstract
Delirium is a syndrome frequently encountered in intensive care and associated with a poor prognosis. Intensive care delirium is mostly based on general and palliative intensive care data in the literature. In this study, we aimed to investigate the incidence of delirium in coronary intensive care unit (CICU), related factors, its relationship with inhospital and follow up prognosis, incidence of age-related delirium and its effect on outcomes.This study was conducted with patients hospitalized in CICU of a tertiary university hospital between 01 August 2017 and 01 August 2018. Files of all patients were examined in details, and demographic, clinic and laboratory parameters were recorded. Patients confirmed with psychiatry consultation were included in the groups of patients who developed delirium. Patients were divided into groups with and without delirium developed, and baseline features, inhospital and follow up prognoses were investigated. In addition, patients were divided into four groups as65 years old, 65-75 yo, 75-84 yo and85 yo, and the incidence of delirium, related factors and prognoses were compared among these groups.A total of 1108 patients (mean age: 64.4 ± 13.9 years; 66% men) who were followed in the intensive care unit with variable indications were included in the study. Of all patients 11.1% developed delirium in the CICU. Patients who developed delirium were older, comorbidities were more frequent, and these patients showed increased inflammation findings, and significant increase in inhospital mortality compared to those who did not develop delirium (p0.05). At median 9-month follow up period, rehospitalization, reinfarction, cognitive dysfunction, initiation of psychiatric therapy and mortality were significantly higher in the delirium group (p0.05). When patients who developed delirium were divided into four groups by age and analyzed, incidence of delirium and mortality rate in delirium group were significantly increased by age (p0.05).Development of delirium in coronary intensive care unit is associated with increased inhospital and follow up morbidity and mortality. Delirium is more commonly seen in geriatric patients and those with comorbidity, and is associated with a poorer prognosis. High-risk patients should be more carefully monitored for the risk of delirium.A delírium gyakran jelentkezik intenzív osztályon ápolt betegek körében, és rossz prognózissal társul. A delírium intenzív osztályos ellátása leginkább általános és palliatív intenzív osztályos adatokon alapul. Ebben a vizsgálatban azt a célt tûztük ki, hogy megállapítsuk a delírium incidenciáját és sajátosságait coronaria intenzív osztályon (CICU), továbbá megállapítsuk prognózisát, életkori eloszlását és a betegkimenetre gyakorolt hatását.A vizsgálatba egy tercier egyetemi kórház CICU-ján 2017. augusztus 1. és 2018. augusztus 1. között ápolt betegeit vontuk be. Részletesen tanulmányoztuk a betegdokumentációkat, rögzítettük a demográfiai, klinikai és laboratóriumi paramétereket. A delírium diagnózisát pszichiáter konzulens erôsítette meg. A betegeket két csoportra osztottuk (delírium vs. delíriummentesség), megállapítottuk a két csoportba kerülô betegek sajátosságait a vizsgálat kezdetén, és prognózisukat a kórházi ápolás és az utánkövetés során. Életkori sajátosságok alapján négy csoportba osztottuk a pácienseket:65 éves, 65–75 éves, 75–84 éves és85 éves, és a különbözô életkori csoportok között összehasonlítottuk a delírium incidenciáját, sajátosságait és prognózisát.1108, különbözô indikációk miatt intenzív osztályon ápolt beteget vontunk be a vizsgálatba (átlagos életkor: 64,4 ± 13,9 év; 66% férfi). Az összes beteg 11,1%-a esetében alakult ki delírium a CICU-n. A delíriumban szenvedô betegek idôsebbek voltak, több kísérô betegségben szenvedtek, magasabb volt a szervezetük gyulladásos szintje, és magasabb volt a mortalitásuk is a kórházi ápolás során, mint azok esetében, akiknél nem alakult ki delírium (p0,05). A delirálók csoportjában az átlagosan 9 hónapos utánkövetés során szignifikánsan magasabb volt a kórházi újrafelvétel, az ismételt infarktus, a kognitív diszfunkció, a pszichiátriai kezelés szükségessége és a mortalitás is (p0,05). Az életkori alcsoportok szerinti felosztásban a delirálók csoportjában az életkor elôrehaladtával szignifikánsan nôtt a delírium és a mortalitás incidenciája egyaránt (p0,05).Amennyiben a coronaria intenzív osztályon ápolt betegnél delírium alakul ki, megnô a morbiditás és mortalitás incidenciája a kórházi ápolás alatt és az utánkövetés során is. A delírium gyakrabban fordul elô geriátriai betegek és társbetegségekkel küzdôk körében, és rosszabb prognózissal társul. A delírium mielôbbi felismerése érdekében a nagy kockázatú betegeket szorosan után kell követni.
- Published
- 2020
- Full Text
- View/download PDF
5. Giant Saccular Aneurysm of the Right Coronary Artery
- Author
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Cihan, Öztürk and Mustafa, Ebik
- Subjects
Incidence ,Coronary Aneurysm ,Humans ,Coronary Artery Disease ,Mucocutaneous Lymph Node Syndrome - Abstract
Coronary artery aneurysm (CAA) is defined as a segmental coronary dilation that exceeds the diameter of the adjacent normal coronary artery 1.5 times. Its incidence in the general population is between 1.5% and 5%. However, CAAs over 10 mm are extremely rare. The cause of CAA in this patient with diffuse coronary artery disease was evaluated as atherosclerosis. CAA lesion was not the cause of acute coronary syndrome in our patient. Therefore, CAAS can remain asymptomatic for many years. Individuals with systemic diseases, such as Kawasaki's disease and Behçet's disease, should be followed up for CAAS.
- Published
- 2021
6. The Effect of Thyroid Stimulating Hormone Level Within the Reference Range on In-Hospital and Short-Term Prognosis in Acute Coronary Syndrome Patients
- Author
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Çağlar Kaya, Mustafa Ebik, Utku Zeybey, Servet Altay, Melik Demir, Muhammet Gürdoğan, and Selcuk Korkmaz
- Subjects
Male ,Acute coronary syndrome ,medicine.medical_specialty ,endocrine system ,Time Factors ,endocrine system diseases ,Turkey ,Cross-sectional study ,thyroid-stimulating hormone ,Thyrotropin ,Reference range ,Logistic regression ,Gastroenterology ,Article ,acute coronary syndrome ,mortality ,prognosis ,Coronary artery disease ,Thyroid-stimulating hormone ,Reference Values ,Internal medicine ,medicine ,Humans ,Euthyroid ,Aged ,Retrospective Studies ,lcsh:R5-920 ,business.industry ,Retrospective cohort study ,General Medicine ,Middle Aged ,medicine.disease ,Prognosis ,Cross-Sectional Studies ,Female ,business ,lcsh:Medicine (General) ,hormones, hormone substitutes, and hormone antagonists - Abstract
Background and objectives: Despite being within the normal reference range, changes in thyroid stimulating hormone (TSH) levels have negative effects on the cardiovascular system. The majority of patients admitted to hospital with acute coronary syndrome (ACS) are euthyroid. The aim of this study was to investigate the effect of TSH level on the prognosis of in-hospital and follow-up periods of euthyroid ACS patients. Materials and Methods: A total of 629 patients with acute coronary syndrome without thyroid dysfunction were included in the study. TSH levels of patients were 0.3–5.33 uIU/mL. Patients were divided into three TSH tertiles: TSH level between (1) 0.3 uIU/mL and <, 0.90 uIU/mL (n = 209), (2) 0.90 uIU/mL and <, 1.60 uIU/mL (n = 210), and (3) 1.60 uIU/mL and 5.33 uIU/mL (n = 210). Demographic, clinical laboratory, and angiographic characteristics were compared between groups in terms of in-hospital and follow-up prognosis. Results: Mean age was 63.42 ± 12.5, and 73.9% were male. There was significant difference between tertiles in terms of TSH level at admission (p <, 0.001), the severity of coronary artery disease (p = 0.024), in-hospital mortality (p <, 0.001), in-hospital major hemorrhage (p = 0.005), total adverse clinical event (p = 0.03), follow-up mortality (p = 0.022), and total mortality (p <, 0.001). In multivariate logistic regression analysis, the high–normal TSH tertile was found to be cumulative mortality increasing factor (OR = 6.307, 95%, CI: 1.769–22.480, p = 0.005) during the 6-month follow-up period after hospitalization and discharge. Conclusions: High–normal TSH tertile during hospital admission in euthyroid ACS patients is an independent predictor of total mortality during the 6-month follow-up period after hospitalization and discharge.
- Published
- 2019
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