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In any E&P organization, drilling new wells is part of field development activity. This allows company to bring into production additional oil from different fields. Number of new wells drilled varies from company to company from a few to hundreds as in case of Petroleum Development Oman (PDO). Drilling new wells is a capital-intensive activity. Contribution to the overall production from new wells makes for higher returns on investment. New oil production, is an integrated activity involving a number of departments and different stakeholders. Information and data come from different sources and has to be validated by different stakeholders. Over the years, this has been done in a traditional manner with smart use of spreadsheets. However, with increase in activity, this way of working became cumbersum and time consuming. In business planning, it is important to select an optimum set of activities for drilling which will generate most new oil from allocated resources and budget. It should also be able to quantify opportunity oil in changing requirements. This means generating alternative sequences and comparing them against a set of KPIs and constraints. This exercise is required to be carried out within a cluster and across different clusters in a business unit. With the use of smart spreadsheets, this was getting difficult and time consuming. Resulting in suboptimal drilling sequence and missed opportunity to increase New Oil production.

Diabetes mellitus (DM) is a metabolic disorder associated with accelerated atherogenesis and an increased risk of atherothrombotic complications. Multiple mechanisms contribute to the prothrombotic status which characterizes DM patients underscoring the importance of antiplatelet therapies used for secondary prevention in these patients. For many years, dual antiplatelet therapy (DAPT) with aspirin and the P2Y12 inhibitor clopidogrel has represented the mainstay of treatment following an acute coronary syndrome (ACS) or in patients undergoing percutaneous coronary interventions (PCI). Although DAPT reduces the incidence of atherothrombotic recurrences, these rates remain high in DM patients underscoring the need for more efficacious therapies. The present manuscript provides an overview on the current status of knowledge on currently available antiplatelet agents, focusing on the benefits and limitations of these therapies in DM patients, and evaluating the potential role of new antithrombotic agents and treatment strategies currently under development to overcome these limitations., Corresponding Author Dr. SP Srinivas Nayak Assistant Professor, Department of Pharmacy Practice, Sultan ul Uloom College of Pharmacy, Hyderabad, Telangana, India

Internet of Things (IoT) process technology is a rapidly emerging technology with great benefits for the pool of individuals, homes, companies and other institutions in general. This technology is used to connect everyday devices to the network to enable additional features such as remote control and access to data, But the network is exposed to several attacks, the most important attacks that cause the problem of overload is event-based attack, Smart stretched attack on the buffer one of the most important attacks on the network, in this research we propose a new algorithm called a Fuzzy Buffer Split (FBS) to defend against these two types of buffer attacks.

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