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One of the activities of professional development for teachers is Scientific Publication. Nonetheless, many teachers have a problem with writing scientific work. Therefore, this community service was done to improve the teachers’ scientific publication through the writing process of a scientific article for journal publication. The type of community service in this research is Participatory Action Research (PAR). The activity of this community service was to provide training/assistance for improving the scientific publication. It was conducted in the form of providing training in article writing for the journal to the teachers in Islamic schools in Teluk Kuantan, especially MAN 1 Teluk Kuantan and it involved 25 teachers. The result of this community service was that the teachers as the training participants had a minimum initial understanding of journal articles and the use in improving learning quality in a class. The average indicator as a whole was only 23.725 and it was categorized as infrequent. All indicators that were questioned were in the ‘infrequent’ category. Meanwhile, based on gender-based motivation, it was found that both genders of the training participant had a motivation that was categorized as ‘frequent’ in participating in the training. However, there was a difference in the aspect for the indicator of being confident to be able to participate well and the readiness of sufficient basic knowledge. The implication of this community service is the importance of this activity and the like for the people to change the mindset and the understanding of the teachers as the training participants to be better.

This service aims to analyze the effect of Character Education training on increasing the competence of Early Childhood Education (PAUD) teachers in implementing character and morality values ​​in PAUD learning. The study was conducted involving 20 PAUD teachers in Bengkalis Regency. The evaluation results show that the training was successful in increasing PAUD teachers' knowledge, skills and understanding of Character Education and Living Values ​​Education. However, there is still potential to further strengthen the integration of the concept in daily practice. The evaluation results also indicate that the training program has a positive impact on the quality of teacher teaching and can create changes in the character and behavior of PAUD children. This research provides important insight into the importance of Character Education training in the context of PAUD education.

Tolerance in social life is a need for Indonesian citizens. However, cases of intolerance and violence in the name of religion frequently occur in socia life and might influence students at university This research aims to assess the level of religious moderation comprehension among students at UIN (Universitas Islam Negeri/State Islamic University) Suska Riau through group counseling sessions. The study utilized a quantitative approach, employing a descriptive pre-experimental Intack Group Comparison design. The findings revealed that students' understanding of a moderate attitude significantly increased after participating in group counseling on moderation, with a positive score of 97.5% and a negative score of 2.4%. The inclusion of religious moderation as a theme in group counseling positively impacted students' comprehension and attitude towards religious moderation within society. Notably, two indicators, national commitment and tolerance, exhibited the most significant improvements, with respective increases of 35% and 29%. These results suggest that employing group counseling centered around religious moderation can serve as a model for enhancing students' understanding of religious moderation in society.

Perubahan kurikulum selalu terjadi menyesuaikan kebutuhan dan kondisi di lapangan. Mendikbud langsung meluncurkan program Merdeka belajar, hal ini disambut dengan kondisi dilapangan yang serba mengkhawatirkan karena adanya musibah yang melanda tidak hanya Indonesia tetapi juga dunia. Musibah tersebut yaitu berupa pandemic corona yang sangat mempengaruhi sendi-sendi kehidupan termasuk ekonomi, pendidikan. Tentu program ini sangat terkait dengan adanya penggunaan dan pemanfaat tekhnologi informasi dalam proses pembelajaran di sekolah. Untuk mendukung program merdeka belajar maka pengabdi ingin melakukan pelatihan dan bimbingan teknis pemanfaatan tekhnologi informasi dalam pembelajaran. Dalam pengabdian ini akan melibatkan para guru di Pelalawan. Pelatihan ini memberikan implikasi bagi guru SD untuk memanfaatkan TIK dalam pembelajaran daring.

Abstract This study describes the initial ability of teachers in carrying out online learning activities. This research was conducted through survey research involving 154 elementary school teachers in Pelalawan and Rengat Regencies, Riau Provinces as the research samples were taken by purposive sampling. Research data were obtained through a survey using google forms and distributed via WhatsApp. Data analysis was carried out descriptively and inferentially using SPSS version 26. Based on the data analysis, it was identified that 97 teachers (63%) choose a combination learning model between offline and online as the most frequently learning model used during the covid-19 pandemic. In carrying out the learning process, 93 teachers (60.4%) chose schools as teaching locations. Regarding the quality of the internet in schools, 110 teachers (71.4%) assessed that the quality of the internet in schools was good and could support learning activities. Furthermore, teachers also apply various ways of teaching online learning, for example, 50 teachers (32.5%) choose to provide interactive material through online media and 45 teachers (29.2%) ask students to learn to use textbooks and give assignments to students in the form of assignments on worksheets, projects, books, etc. The main obstacle for teachers during online learning is that they find it difficult to observe student progress and have difficulty communicating with parents. The efforts made by teachers to adapt online learning is by providing materials/tasks and establishing basic competencies according to student needs.

This study aimed to examine the relationship between facilities and instructors' perceptions of their ability to develop instructional media during a pandemic. This study employed a quantitative approach through the use of a survey. The sample size for this study was 154 elementary school teachers drawn through a purposive sampling technique from Pelalawan and Rengat districts. The data were gathered via a survey administered over WhatsApp and analyzed descriptively and inferentially using SPSS version 26. The findings indicated that all fundamental support facilities for online learning were met 100 % of the time, interactive learning media facilities were met 48.7 % of the time, and assistive devices for students were met 58.4 % of the time. Additionally, 60.4 % of teachers frequently create learning media on their own, 45.5 % frequently generate media independently, and 42.9 % frequently use online learning media. The Pearson Product Moment Correlation Coefficient calculated between facilities and teachers' abilities indicated a significant value of 0.0000.05. As a result, it is possible to conclude that there is a positive and significant association between facilities and the teacher's opinion of their ability to produce instructional media.

The analysis of radicalism attitudes among students is triggered by the lack of supervision of information and communication technology usage. This study aims to find the attitude of radicalism among senior high school students based on gender. The research is designed with a quantitative approach. The data were collected using a questionnaire. This study involved 229 students selected by random sampling, with a total of 107 male and 122 female students. The data were collected using a questionnaire and essay. The data were further analysed qualitatively and quantitatively. The results of this study showed that in Part A, 34% male and 19% female students often sent and shared religious content and conflicts on social media. In Part B, 13% male and 14% female students agreed on courtship, marriages with different religion, polygamy, and divorce. In Part C, 2% male and female students are anti-ideological and uphold Islamic law. Furthermore, in Part D, 67% male and 46% female students declare non-Muslims as infidel, and war is a part of jihad.

Literacy skills are fundamental things that students must have in facing the industrial era 4.0 to be able to meet the needs of life in various situations. Scientific literacy is the ability to understand science, communicate science, and apply science skills to solve problems. However, the scores of Indonesian students on scientific literacy abilities are still far below the international standard scores set by the OECD institution. Seeing this phenomenon, this study aims to describe the profile of students' scientific literacy abilities. The research method used was a survey method. Informants who were used as research samples were 1210 Open University students. Data on students' scientific literacy abilities were collected through an online questionnaire using Google Form, then analyzed descriptively using the help of the SPSS program version 23.00 for Windows. The findings obtained in this study indicate the importance of scientific literacy skills that have a positive impact on knowledge, understanding and skills in using media, especially social media, which is currently often used as a source of information by audiences, especially students. Seeing the results of this study, the researcher recommended the need for universities or leaders so that students could improve students' scientific literacy skills. Keywords: ability, science literacy, natural science learning, covid-19 era, students. ABSTRAK Kemampuan literasi merupakan hal fundamental yang harus dimiliki oleh mahasiswa dalam menghadapi era industri 4.0 untuk dapat memenuhi kebutuhan hidup dalam berbagai situasi. Literasi sains merupakan kemampuan untuk memahami sains, mengkomunikasikan sains, serta menerapkan kemampuan sains untuk memecahkan masalah. Namun, skor siswa Indonesia pada kemampuan literasi sains masih jauh di bawah skor standar internasional yang ditetapkan oleh lembaga OECD. Melihat fenomena tersebut, penelitian ini bertujuan untuk mendeskripsikan profil kemampuan literasi sains mahasiswa. Metode penelitian digunakan adalah metode survey. Informan yang dijadikan sampel penelitian sebanyak 1210 orang mahasiswa Universitas Terbuka. Data kemampuan literasi sains mahasiswa dikumpulkan melalui kuisioner online menggunakan Google Form, kemudian dianalisis secara deskritif menggunakan bantuan Program SPSS versi 23.00 for Windows. Temuan yang diperoleh pada penelitian ini menunjukan pentingnya kemampuan literasi sains yang memberikan dampak positif bagi pengetahuan, pemahaman dan keterampilan dalam menggunakan media terutama media sosial yang saat ini sering dijadikan sumber informasi oleh khalayak terutama oleh kalangan mahasiswa. Melihat hasil penelitian tersebut, peneliti merekomendasikan perlunya universitas atau pimpinan agar mahasiswa dapat meningkatkan kemampuan literasi sains mahasiswa. Kata kunci: kemampuan, literasi sains, pembelajaran ipa, era covid-19, mahasiswa.

Research instruments are an important factor in a study in which the truth of researched results lies that determines the conclusion. Instruments are used to collect data and measure a research variable's object. This study aimed to retest a valid, consistent, and reliable instrument related to multiple intelligences previously developed by McClellan Conti. In this study, Multiple intelligences adapted from American psychologist, Howard Gardner, consisted of nine constructs, namely: (1) physical/kinesthetic, (2) existential/spiritual, (3) interpersonal, (4) intrapersonal, (5) logical thinking, (6) musical/rhythmic, (7) naturalistic, (8) verbal, and (9) visual. Designed as a survey study, it involved 140 respondents from primary education tutors of Universitas Terbuka at Pekanbaru selected using simple random sampling techniques. The data was analyzed using SPSS version 23.00 for Windows. The results showed that all questionnaire items were valid and reliable with a high average Cronbach Alpha reliability value (0.763 0.6), and every statement item has a high value (0.786 – 0.887) with a total construct value of 0.859. This study provides an alternative assessment related to multiple intelligence. Knowing each tutor's multiple intelligences will make the tutor focus more on the superiority of his intelligence. This will have good consequences for the development of the student learning process.

Emotional intelligence has been considered as contributing factor to students’ achievement in their academic life. Unfortunately, this intelligence seems to neglect on the part of students. In SMK (Sekolah Menengah Kejuruan/Vocational School) Negeri 2 Pekanbaru, students had religious program namely Tadarus Al-Qur’an from 2013 until now but this program contributes less to their emotional intelligence. This study is aimed at investigating the relationship between students’ participation in extracurricular activities of Tadarus Al-Qur’an with their emotional intelligence. This study was quantitative and it applied correlational method. Data were collected through questionnaires and 232 students participated in this study. The results were analyzed by product-moment correlation test and linear regression. The results showed that based on the grouping of students’ answer scores for emotional intelligence as follows: high group of 9.57%, medium group 69.57% and low group, 20.87%. This is based on the product-moment correlation test results and linear regression test results, both at the 5% level and at the 1% level. It can be concluded that there was a significant relationship between students’ participation in extracurricular activities Al-Qur’an and their emotional intelligence.

The Indonesian government is trying to implement a learning process based on information and communication technology. However, there are still weaknesses in the use of the internet in the learning process among students. Therefore, this article aims to describe the activities of students during the implementation of hybrid learning in mathematics learning and find out the results of student learning in mathematics through the application of Hybrid Learning. The research method used in this article is a true experimental design with a research sample of SMA Negeri 1 Pekanbaru students, whose schools have easy internet access. To obtain primary data from the field, tests are used to measure student mathematics learning outcomes. After each data is collected and tabulated, the data will be analyzed using statistical parametric analysis with the t test using the help of SPSS Version 18.00. The results showed that there were differences in student learning outcomes between those studying with the Hybrid Cooperative Learning method and students learning with conventional methods in SMA Negeri 1 Pekanbaru. The difference is confirmed again by the mean value of the experimental class 34.55 while the mean control class is 31.35. The results of this calculation indicate that the ability of the experimental class students is better than the control class students. This means that the value of the experimental class is better.

Background: Hearing loss in paediatric age group may be inherited, developmental or caused by maternal rubella. It may also be due to complications at birth or certain infections such as meningitis and measles. Ototoxicity and exposure to excessive noise also contribute significantly. Majority of hearing loss in children can be prevented primarily. We aimed to share our findings on assessing the hearing thresholds of pupils in deaf schools in Northwestern Nigeria. Participants and Methods: This was a cross-sectional study which assessed the hearing threshold of pupils in deaf schools in Kaduna metropolis, Kaduna, Nigeria. Approval was obtained from the State Ministry of Health Ethics Committee. Multi-staged sampling method was used to enrol 430 deaf pupils. Consent was obtained and a structured pre-tested questionnaire was used to generate data on the participant's biodata, history and detailed examination findings as well as pure-tone audiometry. Collated data were documented and entered into Statistical Product and Service Solutions version 20 for windows then analysed. Results: Mean pure-tone average of the right ear was 103.4 ± 8.3 and the left ear was 104.3 ± 8.9. Majority had bilateral profound hearing loss (99.0%). Severe hearing loss was seen in 0.9%, whereas the remaining 0.1% had moderate hearing loss. The hearing loss sensorineural in majority (97.6%) and the remaining 2.4% had mixed hearing loss. High-frequency hearing loss predominated (98.6%). Conclusion: Majority of the deaf pupils had bilateral, profound, sensorineural hearing loss, involving higher frequencies.

Promotion is one way to spread information, so as to persuade/influence the audience to be willing to be loyal, accept, or buy towards a company or product. One form of promotional media that is effective in increasing the prospect of an object is online comics. Online comics are digital media that are dynamic and in accordance with technological developments. Based on this, this study aimed to evaluate the use of online comics among Universitas Terbuka students as a means of education and promotion. This research is development research using the ADDIE model with limitation of only on response test or evaluation of the use of online comics. The research was conducted by involving 60 students from various study programs. The data collection was done using an online questionnaire consisting of seven constructs with 34 questions related to evaluating the use of online comics. The data collected was then analyzed using SPSS version 23.00 for Windows. The results showed that the students' evaluation of the use of online comics in the seven constructs had an average of 3.11 in the "good" category. Therefore, students as agents of change in education are expected to be able to think openly about changes and alternatives offered by technology to improve the quality of learning.

This article is based on the limited lecture model for Kapita Selekta Mathematics (KSM) courses. The purpose of writing this article is to identify the perception of lecturers and students to PBW in Prodi PMT FTK UIN Suska Riau seen from: 1) the existence of math-based learning website; 2) understanding of lecturers and students regarding the existence of PBW; and 3) problems in implementing PBW. This article uses quantitative descriptive research. The subjects involved consisted of three lecturers and seven students. Data were collected through PBW utilization questionnaires. Data were analyzed using quantitative descriptive. This article presents some conclusions, among others: 1) lecturers and students do not understand the importance of PBW; 2) PBW has the advantage and good quality in supporting the learning process of mathematics; and 3) the main problem in implementing PBW is infrastructure especially in WiFi /hotspot facility and lecturer's ability

This article is based on the limited lecture model for Kapita Selekta Mathematics (KSM) courses. This article aims to reveal the results of technology validation of the website of the mathematics proficiency course (KSM) on UIN Suska Riau students. This article uses a development research model that uses Sugiyono's research steps but only limited to two stages, namely design stage and product validation stage. The validated aspect of the learning website is graphic feasibility and program feasibility with indicators: 1) the size of the learning website, 2) the design of the learning website, and 3) the design of the content of the learning website. The validation instrument is a questionnaire using Likert scale that is filled by three expert technology experts. Assessment of the validity of the learning web on the aspect of feasibility of the graphics resulted in a total validity value of 3.9 with valid categories. As for the web learning on the feasibility aspect of the program to produce the value of validity as a whole that is 4 with valid categories

Objective: This study explored the influence of the life course on mental health by identifying key trends, seminal works, and themes in existing research. Additionally, it highlights the major discussions at the intersection of life course and mental health., Methods: Documents were extracted from the Web of Science Core Collection (WoSCC), to systematically analyze themes on mental health outcomes across the life course. The analysis was based on key bibliometric tools, including VOSviewer 1.6.11, R Studio software, and GraphPad Prism 9 to analyze the evolution and impact of scholarly contributions in this domain., Results: The accumulated body of research concerning the life course's impact on mental health, which began to emerge around 1990 displayed a consistently upward trend. Predominant contributions originate from developed nations and frequently look into the psychosocial determinants of mental health over life course. Life course and mental health studies have been extensively infused with biopsychosocial frameworks that consider the role of genetic makeup, neurodevelopment, cognition, affect, sociocultural dynamics, and interpersonal relationships. Life course theory application in mental health highlight the substantive effects of accumulated adversities, notably social determinants of health, adverse childhood experiences (ACEs), and their implications for subsequent mental health outcomes., Conclusion: The nexus of life course and mental health outcomes demands further scholarly interrogation, particularly within underserved regions, to strengthen protective mechanisms for vulnerable populations., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Zhang, Shaojun, Akintunde, Okagbue, Isangha and Musa.)

Methods: A bibliographic survey was carried out between 2020 and 2022 using two databases: PubMed/MEDLINE and Scientific Electronic Library Online (SciELO) and the information source Academic Google, irrespective of language or geography., Results: In the first nutrition consultation (FNC), there should be an investigative direction focused on nutritional interventions in the short, medium, and long term. The record in the patient's medical record is relevant for carrying out the consultation, according to the recommendations of the normative councils of medicine and nutrition. The main steps to be followed are the investigation of the presence of food allergies and intolerances; the drugs/nutritional supplements in use; changes in the digestive tract; the presence or absence of picamalacia; and socioeconomic and lifestyle data. In addition, it is necessary to carry out laboratory evaluations, semiological assessment, anthropometric assessment, and assessment of food consumption. In the end, the nutritional approach should be composed of calculation of energy and macronutrient and micronutrient needs, intervention in nutritional status deviations, nutritional guidelines, and nutritional therapeutic planning of return, focusing on adherence to treatment., Conclusion: The first nutrition consultation may represent investigative steps that help the clinical nutritionist in the management, allowing a longitudinal and specific nutritional therapeutic planning for patients assisted in large reference centers for hematological disease., Competing Interests: The authors declare that they have no conflicts of interest., (Copyright © 2023 Julia da Silva Goncalves dos Santos et al.)

Background/introduction: Conflict-induced displacement continue to be a pressing public policy concern due to the adverse effects on the well-being of internally displaced persons (IDPs). Understanding the integration process of these individuals, particularly the role of solidarity and social integration in fostering a sense of belonging and improving their community experiences and psychological well-being, remains unclear. This study investigates the role of community satisfaction in the relationship among social integration, solidarity, and psychological health of IDPs in Cameroon., Methods: Cross-sectional data from 428 displaced individuals in the Ntui subdivision, Cameroon, were analyzed using structural equation modeling (SEM). This technique tested four latent variables: social integration, solidarity, community satisfaction, and psychological health., Results: The results show a direct association between solidarity and both community satisfaction (β = 0.282; p < 0.001) and psychological health (β = 0.137; p < 0.01). Community satisfaction also has a direct relationship with the psychological health of the IDPs (β = 0.292; p < 0.001). An indirect effect of solidarity on psychological health through community satisfaction was observed (β = 0.084 (SE = 0.025, CI = [0.047, 0.129], p < 0.001)). However, no mediational effect of community satisfaction was found on the association between social integration and psychological health. The model accounted for 7% of the variance in community satisfaction (R 2  = 0.07) and 20% of the variance in psychological health (R 2  = 0.20). Conclusion: The findings indicate a strong sense of solidarity among the displaced persons in the studied communities in Cameroon, which promotes their psychological health via community satisfaction. As such, interventions should aim to foster solidarity among displaced persons to enhance their community experiences and psychological health., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Authors.)

Background/purpose: The COVID-19 outbreak created unique policy challenges for vaccinating special groups like migrants. As part of sustainable development goals, the equitable distribution of the COVID-19 vaccine can contribute to ensuring health for all. This study examined COVID-19 vaccine uptake among foreign migrants in China based on sociodemographics, cultural beliefs, past vaccine behaviors, and psychosocial factors., Design: An online cross-sectional survey was conducted among foreign migrants in mainland China via social media platforms from 21 November through 20 December 2021. Bivariate (unadjusted odd-ratio) and multivariate logistic regression analyses were performed to establish the correlates of COVID-19 vaccine uptake., Result: Surveyed foreign migrants that are culture neutral (AOR: 2.5, CI: 95%, 1.02-5.90, p = 0.044), willing to pay for vaccination (AOR: 2.27, CI: 95%, 1.18-3.98, p = 0.012), believe in vaccine efficacy (AOR: 3.00, CI: 95%, 1.75-5.16, p < 0.000), have poor psychological health (AOR: 1.96, CI: 95%, 1.14-3.38, p = 0 0.014), and have higher perceived seriousness of COVID-19 (AOR: 2.12, CI: 95%, 1.26-3.57, p = 0.005) are more likely to receive COVID-19 vaccine. Those migrants with a history of declining vaccination (AOR: 0.34, CI: 95%, 0.18-0.65, p = 0.000) and middle-income earners $1701-3500 (AOR: 0.43, CI: 95%, 0.23-0.82, p = 0.010) are less likely to receive the COVID-19 vaccine., Conclusion: This study brings a unique perspective to understanding vaccine behavior among international migrants in China. There is an urgent call from the World Health Organization and countries for complete vaccination and efforts to improve vaccine coverage. However, fewer studies have been conducted globally on the vaccination of migrant populations. The current study provides empirical information to increase the knowledge of the correlates of vaccine behavior among immigrants in countries around the globe. Future studies should conduct cross-country comparisons to understand the factors associated with increasing vaccination rates among immigrant populations to formulate a strong policy to increase vaccine coverage among immigrant populations across countries., Competing Interests: The authors declare that no conflict of interest in respect of this manuscript., (© 2023 The Authors.)

Major databases were searched from January 2012 to August 2021 and 54 eligible studies were included in the meta-analysis to estimate the overall mean of total volatile basic nitrogen (TVB-N) in meat. The mean of TVB-N was 24.96 mg/100 g (95 % CI:23.10-26.82). The pooled estimate of naphthoquinone, curcumin, anthocyanins, alizarin and betalains were 25.98 mg/100 g (95 %CI:19.63-32.33), 30.03 mg/100 g (95 %CI: 24.15-35.91), 24.92 mg/100 g (95 %CI: 22.55-27.30), 23.37 mg/100 g (95 %CI:19.42-27.33) and 19.50 mg/100 g (95 %CI:17.87-21.12), respectively. Meanwhile, subgroups based on meat types showed that smart film was most used in aquatic products at 27.19 mg/100 g (95 %CI:24.97-29.42), followed by red meat at 19.69 mg/100 g (95 %CI:17.44-21.94). Furthermore, 4 °C was the most storage temperature used for testing the performance of smart films at 25.48 mg/100 g (95 %CI:23.05-27.90), followed by storage at 25 °C of 25.65 mg/100 g (95 %CI:22.17-29.13). Substantial heterogeneity was found across the eligible studies (I 2  = 99 %, p = 0.00). The results of the trim-and-fill method demonstrated publication bias was well controlled., (Copyright © 2022. Published by Elsevier Ltd.)

The success of mRNA vaccines against SARS-CoV-2 implies that this technology can be applied to target any pathogen. However, the scientific production and research trends using the bibliometric method are still unknown. The top 100 most cited articles on mRNA vaccine research were obtained from the Scopus database from 1995 to 2021. Bibliometrix, an R -Package, and VOSviewer 1.6.11 were used for data analysis. There is a rapid growth in scientific outputs with a gradual increase in 2021. The United States produced 45 (45%) of the articles, followed by Germany with 15 (15%) and Israel with 10 (10%). The New England Journal of Medicine published the most papers in this field 13 (13%), followed by Nature 6(6%). Barney S. Graham was the most productive author among the top 100 most cited mRNA vaccine articles. University of Pennsylvania Perelman School of Medicine, US, was the top ranking institution, having 37 (37%). The visualization map clearly and spontaneously displayed the current state and research hot spots of mRNA research from a specific perspective. The most frequent keywords were COVID-19, vaccine, mRNA vaccine, mRNA, SARS-CoV-2, and immunogenicity, among others. A systematic review of the articles provided evidence that out of 100 articles, approximately 25 (25%) were focused on vaccine production and evaluation, followed by 26 (26%) in mRNA vaccine safety and efficacy, 23 (23%) were into mRNA vaccination, 23 (23%) considered risk factors associated with mRNA vaccination, while 8 (8%) of the articles covered the issue of mRNA vaccine delivery. In addition, 42% of the articles focused on COVID-19, 17% on cancer, 8% on influenza virus, 4% on COVID-19 and kidney disease, 3% COVID-19 and myocarditis, and 3% on rabies virus, among others. The findings of this systematic and thematic analysis provided the knowledge basis for further research on mRNA vaccines globally.

In impoverished nations, donkeys help people make a living. The welfare of donkeys in Sudan is neglected compared with developed countries. However, there is no information available about donkey welfare in Nyala. This study aimed to assess the welfare of donkeys in Nyala. Donkeys were divided into two groups (n = 50), working and nonworking. The donkeys' physical, emotional, and clinical parameters and an owner's interview were assessed. There were significant differences in body condition scores: 37% and 47% of working and nonworking donkeys, respectively, had ideal body condition scores, while 13% of working donkeys were emaciated. Of the working and nonworking 33% and 19% had hoof problems, respectively. Fifteen percent of working donkeys had ocular discharge, and 25% had wounds. In working donkeys, 7% and 5% depressive and aggressive behavioral responses, respectively, were observed. Furthermore, there were significant differences in tools used for hitting donkeys, with 33% and 17% of owners using a stick and whip, respectively, for hitting working donkeys. Eighty-two percent of owners feed their donkeys one to three times daily (50% working and 32% nonworking donkeys), and free access feeding was only observed in 18% of nonworking donkeys. There were no significant differences (P > .06) in emotional parameters. We conclude that working donkeys suffer from multiple welfare problems more than nonworking donkeys in Nyala. More awareness, veterinary services, and research are needed to improve donkey care in Nyala., (Copyright © 2022. Published by Elsevier Inc.)

Background: Indigenous Sudanese cattle are mainly indicine/zebu (humped) type. They thrive in the harshest dryland environments characterised by high temperatures, long seasonal dry periods, nutritional shortages, and vector disease challenges. Here, we sequenced 60 indigenous Sudanese cattle from six indigenous breeds and analysed the data using three genomic scan approaches to unravel cattle adaptation to the African dryland region., Results: We identified a set of gene-rich selective sweep regions, detected mostly on chromosomes 5, 7 and 19, shared across African and Gir zebu. These include genes involved in immune response, body size and conformation, and heat stress response. We also identified selective sweep regions unique to Sudanese zebu. Of these, a 250 kb selective sweep on chromosome 16 spans seven genes, including PLCH2, PEX10, PRKCZ, and SKI, which are involved in alternative adaptive metabolic strategies of insulin signalling, glucose homeostasis, and fat metabolism., Conclusions: Our results suggest that environmental adaptation may involve recent and ancient selection at gene-rich regions, which might be under a common regulatory genetic control, in zebu cattle., (Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.)

Background: The Journal of African Health Sciences (AHS) is an internationally refereed journal in the field of health sciences with vast research contributions in the world and Africa region., Objective: The study aimed to document the scientific production and explore the AHS research bibliometric characteristics since its first issue., Methods: A comprehensive retrospective bibliometric analysis was performed on AHS published documents indexed in Web of Science (WoS) and Scopus since the journal's first issue. The analysis was done using SPSS v. 22.0, Bibliometrix Package in R, and VOSviewer v.1.6.15., Results: A total of 1649 and 1879 documents indexed in Web of Science (WoS) and Scopus were retrieved. The annual number of publications showed a significant increase in both databases. The most contributing countries (in WoS vs. Scopus) were; Nigeria (n = 393 vs. 276), Uganda (215 vs. 220) and South Africa (143 vs. 101).The most productive authors were "Tumwine JK", "Mayanja-Kizza H", and "Ocama P". Makerere University, The University of Ibadan, and University of Nigeria were the most contributive institutions. International agencies mainly from the USA were the main funders of AHS documents. Analysis of keywords revealed the dominance of research topics with keywords such as HIV/AIDS, Tuberculosis, Malaria, Obesity, Hypertension, risk factors, infection, mortality, amongst others., Conclusions: This analysis has revealed the progress in the development and growth of scientific research from AHS. Moreover, top-cited documents-analysis has reflected its focus on health issues relevant to Africa. This analysis would help in evidence-based descriptions of AHS research output., (© 2022 Musa TH et al.)

Background and Objective: Adipose-derived mesenchymal stem cells (AdMSC) are multipotent adult mesenchymal cells isolated and cultured from the stromal vascular fraction derived from adipose tissue. The present study was conducted to analyze the global trends in AdMSC research using bibliometric and visual analysis tools., Methods: The literature search was done on February 13, 2022, using appropriate keywords and inclusion-exclusion criteria from the Scopus database. The extracted data were retrospectively analyzed and visualized using Bibliometrics and R packages and VOSviewer., Results: Preliminary analysis identified 1569 documents from the Scopus database published between 2005 and 2021. The average citations received per document was 26.51, whereas the average citations per year per document was 3.347. In addition, the selected documents had an h -index value of 90. China was the most productive country, whereas Seoul National University (South Korea) was identified as the most productive institute/university in AdMSC research. In addition, the National Natural Science Foundation of China funded the most research studies in AdMSC research., Conclusion: The findings from this study indicate a progressive increase in interest among the research community towards AdMSC, suggesting promising prospects in the coming years., Competing Interests: All authors declare that there exist no commercial or financial relationships that could, in any way, lead to a potential conflict of interest., (© 2022 The Authors.)

Introduction: Cancer is a major public health problem and a global leading cause of death where the screening, diagnosis, prediction, survival estimation, and treatment of cancer and control measures are still a major challenge. The rise of Artificial Intelligence (AI) and Machine Learning (ML) techniques and their applications in various fields have brought immense value in providing insights into advancement in support of cancer control., Methods: A systematic and thematic analysis was performed on the Scopus database to identify the top 100 cited articles in cancer research. Data were analyzed using RStudio and VOSviewer.Var1.6.6., Results: The top 100 articles in AI and ML in cancer received a 33 920 citation score with a range of 108 to 5758 times. Doi Kunio from the USA was the most cited author with total number of citations (TNC = 663). Out of 43 contributed countries, 30% of the top 100 cited articles originated from the USA, and 10% originated from China. Among the 57 peer-reviewed journals, the "Expert Systems with Application" published 8% of the total articles. The results were presented in highlight technological advancement through AI and ML via the widespread use of Artificial Neural Network (ANNs), Deep Learning or machine learning techniques, Mammography-based Model, Convolutional Neural Networks (SC-CNN), and text mining techniques in the prediction, diagnosis, and prevention of various types of cancers towards cancer control., Conclusions: This bibliometric study provides detailed overview of the most cited empirical evidence in AI and ML adoption in cancer research that could efficiently help in designing future research. The innovations guarantee greater speed by using AI and ML in the detection and control of cancer to improve patient experience.

The global market for imported, high-quality priced foods has grown dramatically in the last decade, as consumers become more conscious of food originating from around the world. Many countries require the origin label of food to protect consumers need about true characteristics and origin. Regulatory authorities are looking for an extended and updated list of the analytical techniques for verification of authentic oils and to support law implementation. This review aims to introduce the efforts made using various analytical tools in combination with the multivariate analysis for the verification of the geographical origin of oils. The popular analytical tools have been discussed, and scientometric assessment that underlines research trends in geographical authentication and preferred journals used for dissemination has been indicated. Overall, we believe this article will be a good guideline for food industries and food quality control authority to assist in the selection of appropriate methods to authenticate oils., (Copyright © 2021 Elsevier Ltd. All rights reserved.)

Background: Mycetoma is a neglected tropical disease that attracts little attention in regard to research and publications and hence this study was undertaken to determine the trends and global scientific research output in mycetoma-related fields., Methods: Mycetoma data were retrieved from the Web of Science (WoS) and Scopus databases. The MeSH Browser was used to extract relevant keywords. Biblioshiny software (R-studio cloud), VOSviewer v. 1.6.6 and SPSS software were used for data management., Results: Research trends on mycetoma increased globally from 1999 to 2020. The results were 404 documents (4444 citations) in WoS and 513 documents (5709 citations) in Scopus, and the average number of citations per article was 11 in WoS and 11.13 in Scopus. There was a significant association between the total number of citations and the total citations per year in both WoS (r=0.833, p<0.0001) and Scopus (r=0.926, p<0.0001). Sudan, India, the Netherlands and Mexico were the top-ranking productive countries for mycetoma publications in WoS, while India, the USA and Mexico were the top-ranking countries in Scopus. Articles on mycetoma were mainly published in PLoS Neglected Tropical Diseases, the International Journal of Dermatology and the Journal of Clinical Microbiology. A. H. Fahal from the Mycetoma Research Centre, University of Khartoum, Sudan, had the highest number of citations in mycetoma research during 1999-2020, followed by W. W. J. van de Sande from the Erasmus Medical Centre, University of Rotterdam, the Netherlands, during 2003-2020., Conclusion: The analysis provides insight into a global overview of Mycetoma research. In addition, the analysis holds a better understanding of the development trends that have emerged in Mycetoma over the past 21 years, which can also offer a scientific reference for future research., (© The Author(s) 2021. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.)

Introduction: COVID-19 pandemic public health emergency is one of the worse disease outbreaks in the history of infectious disease. The consequence has resulted in over 4 million deaths globally. Therefore, a more in-depth understanding of the dynamics of the disease, vaccine development, and safety has become crucial for the disease eradication., Objective: The study adopted bibliometric analysis to identify the global contribution in COVID-19 and Vaccine Safety and analyzed the current status, development, and research hotspots to reference for future research directions., Methods: Studies published between January 1, 2019 and July 11, 2021 were retrieved from the Scopus database. Data analysis and visualization were conducted using VOSviewer ver 1.6.6, Bibliometrix app. (Using R)., Results: A total of 1827 publications with 12.14 average citations per document were identified. These publications were published in 796 journals by 10,243 authors (with 5.61 authors per document) from 80 countries/regions. About 33.75% of the researches were from the developed countries. The USA, China, and India were top contributors for scientific research on COVID-19 and vaccine safety. The "Vaccine" is the most productive journal with 58 articles. Li Y, NA NA, and Liu X were the top three prolific authors. Furthermore, "Human," "Coronavirus disease 2019," and "Drug safety," were the most common frontier topics., Conclusions: Our analysis highlights the characteristics of the most influential articles on COVID-19 related to vaccine safety. The findings provided valuable insight into the scientific research progress in this domain and suggest scaling-up research and information dissemination on COVID-19 and vaccine safety.

Introduction : The Ebola Virus outbreak in Africa is believed to be one of the deadliest viral infections that causes severe hemorrhagic fever in human and nonhuman primates, which has resulted in increased mortality rates in the affected African countries. Thus, the current study mapped and quantified global research output and trends in the EBOV vaccine publications via a bibliometric analysis. Methods: Publications about the Ebola virus vaccine were extracted from the Web of Science and Scopus databases. HistCite, Bibliometrix, an R package, and VOSviewer.Var1.6.6 were used for data mapping and analysis. Results: A total of 541 (WoS) and 511 (Scopus) documents were included, with a cumulation of 24,611 citations in both databases. These documents were published in 141 journals in the Wos and 185 in Scopus. The USA was the most productive country with 206 (38.08%) publications in the Wos. Although the top-cited authors are from the USA, the United Kingdom, and Canada, only one author from Africa "Samai M" from the University of Sierra Leone contributed 13 publications. Meanwhile, the Journal of Infectious Diseases was the most productive (45, 8.32%) in this field. Conclusion: The study provides insight for researchers and health policy on the trends and progress of the EBOV vaccine research and development, focusing on the hot topics, research collaboration, and research dearth that requires urgent redress to fast-track an all-inclusive EBOV vaccine development.

Thirty-nine years ago, scrub typhus (ST), a disease, was not among the China's notifiable diseases. However, ST has reemerged to become a growing public health issue in the southwest part of China. The major factors contributing to an increased incidence and prevalence of this disease include rapid globalization, urbanization, expansion of humans into previously uninhabited areas, and climate change. The clinical manifestation of ST also consists of high fever, headache, weakness, myalgia, rash, and an eschar. In severe cases, complications (e.g. multi-organ failure, jaundice, acute renal failure, pneumonitis, myocarditis, and even death) can occur. The diagnosis of ST is mainly based on serological identification by indirect immunofluorescence assay and other molecular methods. Furthermore, several groups of antibiotics (e.g. tetracycline, chloramphenicol, macrolides, and rifampicin) are currently effective in treating this disease. This fact suggests the need for robust early diagnostic techniques, increased surveillance, and prompt treatment, and develop future vaccine.

Objective: A bibliometric analysis was conducted to build an all-inclusive view of the status of research on hepatitis A virus (HAV) for facilitating researchers, health professionals, and policymakers to understand the characteristics of research output in this particular domain., Methods: A comprehensive search was conducted in the Web of Science database. The obtained data were exported into Microsoft Excel 2019, OriginPro 2018 and VOSviewer software for windows., Results: From 1985 to 2019, a total of 5,950 studies on HAV were published, with an overall h-index of 105, and 90,350 total citations. The most cited article on HAV was "Classification of chronic viral hepatitis: a need for reassessment" authored by Scheuer in the Journal of Hepatology with a total of 1,121 citations. The most cited article on HAV vaccine was "A controlled trial of a formalin-inactivated hepatitis A vaccine in healthy children" by Werzberger et al. in the New England Journal of Medicine with 401 citations. The most frequent year of publication was 2019 (n = 250). The largest number of studies were funded by the United States Department of Health Human Services (n = 199). The organization with the highest number of publications was the United States Centers for Disease Control and Prevention (n = 228). The United State of America (n = 1,500) was the country with the most publications. 'Vaccine' was the leading journal with 299 publications., Conclusions: The highest numbers of studies were published in developed countries. There is a clear need for interdisciplinary research approaches to evaluate and intervene in HAV endemic areas.

The study provides a comprehensive analysis of trends of the global scientific research on the effects of the COVID-19 Pandemic on Mental health from the first published literature up to June 27, 2021. Relevant documents were searched using mesh terms based on the query of two searches, "COVID-19 & Mental Health" scenarios joined by the Boolean operator "AND" to retrieve relevant literature using the Web of Science (WOS) database. Bibliometric indicators were analyzed using HistCite, Bibliometrix, an R package, and VOSviewer.Var1.6.6. A total of 5449 publications with an h-index of 97 were retrieved from the database. Overall, articles retrieved were written by 24123 authors, published in 1224 journals, 132 countries represented, and 10.01 average citations per document. Kings College London led the list of contributing institutions with 76 articles. The United States Department of Human Health Services, the National Institutes of Health, the USA, and the National Natural Science Foundation of China was the top funding agencies that enhanced research on mental health and supported more than 180 articles. USA contributed the most significant proportion 1157 (21.23 %) of COVID-19 Pandemic on Mental health publication closely followed by China in the number of publications 741(13.60 %). The study provides insight into the global research perspective for the scientific progress on the COVID-19 Pandemic public health emergency and the mental health issues, thus significantly impacting and supporting intervention towards improving people's mental health post-COVID-19 outbreak., (Copyright © 2021 Elsevier B.V. All rights reserved.)

The coronavirus disease 2019 (COVID-19) global public health emergency, has exposed the fragility of health systems. Access to healthcare became a scarce commodity as healthcare providers and resource-poor populations became victims of the novel corona virus. Therefore, this study focuses on Africa's readiness to integrate telemedicine into the weak health systems and its adoption may help alleviate poor healthcare and poverty after COVID-19. We conducted a narrative review through different search strategies in Scopus on January 20, 2021, to identify available literature reporting implementation of various telemedicine modes in Africa from January 1, 2011 to December 31, 2020. We summarized 54 studies according to geographies, field, and implementation methods. The results show a willingness to adopt telemedicine in the resource-poor settings and hard-to-reach populations, which will bring relief to the inadequate healthcare systems and alleviate poverty of those who feel the burden of healthcare cost the most. With adequate government financing, telemedicine promises to enhance the treating of communicable and non-communicable diseases as well as support health infrastructure. It can also alleviate poverty among vulnerable groups and hard-to-reach communities in Africa with adequate government financing. However, given the lack of funding in Africa, the challenges in implementing telemedicine require global and national strategies before it can yield promising results. This is especially true in regards to alleviating the multidimensionality of poverty in post-COVID-19 Africa., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2021 People's Medical Publishing House Co. Ltd. Publishing service by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.)

Introduction: In Sudan, cancer a common health challenge, is the leading cause of death after malaria and viral pneumonia. The aim of the review is to determine the risk factors associated with esophageal cancer (EC) among Sudanese population., Methods: All published online data concerning EC epidemiology, diagnosis, and management in Sudan were studied., Results: The prevalence of EC in Sudan is ranked fourth among cancer types in males and fifth in females. The squamous cell carcinoma is more predominant than adenocarcinoma. The dietary, dysplasia and teeth loss, cigarette smoking, age, sex, GERD, genetic and environmental interactions remain a risk for developing EC in clinical practice. A significant challenge for treatment is that most of EC patients were often diagnosed in advanced stages due to the lack of early clinical symptoms. Management of EC depends on patient fitness and tumor stage, endoscopic removal was used for early tumors, while chemotherapy, chemo-radiotherapy, surgical resection, or combinations of these were used for advanced tumors. Despite improvements in the management and treatment of EC patients, the general outcome remains very poor. Furthermore, using molecular techniques to better understand the etiology of EC, it may assist in identifying complicated and critical issues and improve therapy towards a new treatment strategy., Conclusion: The remarkable factors associated with EC among Sudanese are geographical variation, environmental factors, ethnic differences, dietary and social habits.

Introduction: Scrub typhus (ST) is an acute febrile infection and remains a significant health problem globally. This study aimed to determine the factors associated with ST infection in Luhe District, China., Material and Methods: The case-control study was conducted among 116 cases identified through passive surveillance systems over three years.The control subjects were 232 living in the same village for more than six months without any history of ST infection were selected by matching to the age (within 5-years) and identified through active surveillance. Statistical analyses were performed using SPSS v. 25.0 for Windows (IBM SPSS, Chicago, IL, USA)., Results: The mean age of confirmed persons was 58.1(SD=10.15) years, while control subjects were 56.14 (11.57).There is no significant difference in gender, age, education, and occupations between case and control. Farmers had the most significant number of cases among occupational groups. The three factors that were significantly associated with an increased odds of having ST infection are bundling or moving waste straw (OR: 1.94, 95%CI; 0.99,381), morning exercise in the park or field (OR: 4.74 95%CI; 1.19, 18.95), and working as labourer in the vegetable field (OR:1.02, 95%CI:1.02,3.19)., Conclusions: Our findings suggested establishing a prevention and control strategy for these groups to lower ST development risk.

Objectives: Between 2010 and 2020, Africa witnessed several outbreaks of Ebola virus disease (EVD), each presenting with varying case fatality rate (CFR) and other socio-economic impacts. This study aims to summarize the CFR and identify potential factors that influenced the severity of EVD outbreaks in Africa., Study Design: This was a systematic review and meta-analysis of EVD outbreaks published between January 2010 and March 2020, using Web of Science, Scopus, and PubMed databases., Methods: Only English-language articles and reports, including the number of cases and deaths during the outbreak in Africa, were considered. The quality of the included articles was assessed using Murad's quality assessment tool. The analysis was conducted using Stata (version 12), pooled effect sizes were calculated using the random-effects model, and heterogeneity was tested for using the I 2 statistic., Results: Thirteen studies with 32,300 cases and 13,727 deaths were identified, whose pooled CFR was 60% (95% confidence interval [CI]: 47-73%). The most EVD-affected countries were the Democratic Republic of Congo with five outbreaks and a pooled CFR of 65% (95% CI: 59-71%), followed by Uganda with three outbreaks and CFR of 83% (95% CI: 60-99%). Zaire ebolavirus caused the most outbreaks (10), with a CFR of 58% (95% CI: 45-71%). Besides, outbreaks with fewer than 1000 cases reported a higher CFR rate (65%, 95% CI: 54-75%) compared with those with more cases (51%, 95% CI: 33-69%)., Conclusion: The study has revealed a considerably high CFR caused by the recurrent EVD outbreaks in Africa. It also notes an implementation gap in the prevention and control strategies and thus identifies a need to strengthen the surveillance systems and response mechanisms to enable early detection and prompt control of future outbreaks., (Copyright © 2021 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.)

Objective: The aims of this study were to analyze the characteristics of the 100 top-cited articles on scrub typhus (ST), and to assess the present research landscape and future research directions using bibliometric analysis., Methods: Web of Science was used to conduct a bibliometric analysis of the 100 top-cited articles on ST. The articles were analyzed by publication year, number of citations, document type, journals, keywords, institutions, country of origin, and authorship., Results: The top 100 articles on ST were published between 1945 to 2017. The number of citations ranges from 39 to 227 and the interquartile range was 35.5. The United States published the highest number (n=21) of articles. Mahidol University was the most prolific institution in terms of articles (n=14). The American Journal of Tropical Medicine and Hygiene was the journal with the most articles (n=14), and Paris DH was the most productive author in terms of the Hirsh-index, which was 10 for that author. The study revealed a significant correlation between the total number of citations and the number of authors (r=0.668, p < 0.001), number of institutions (r=0.692, p < 0.001), number of years since publication (r=0.869, p < 0.001), and number of countries involved (r=0.963, p < 0.001)., Conclusion: The findings of this study provide landmarks in the publication and citation frequency of the most influential articles on ST. In addition, this study provides useful information for readers and health policy-makers in evaluating the literature on ST.

Introduction: In low-income countries, Hepatitis E infection is a common cause of acute hepatitis. So far, only two recombinant vaccines (rHEV and HEV 239) have been developed against Hepatitis E virus (HEV). Of which HEV 239 is licensed in China, but is not yet available in any other country., Objective: This study aims to discuss epidemiology, diagnosis, available vaccines for HEV, and provides an overview of 100 top-cited studies on HEV., Methods: A bibliometric analysis was conducted on the topic "HEV" through a systematic search of the Web of Science. The keywords used were "Hepatitis E" and retrieved articles were assessed for number of attributes., Results: The search returned a total of 3,235 publications, cited 95,858 times with h-index 129. The main finding for the 100 top-cited articles on HEV showed: number of authors ranging from 1 to 23, cited references range from 4 to 304, global citations score per year range from 6.61 to 175, and global citations score range from 148 to 791. Of the 100 top-cited studies, the authors who published most articles are Purcell (n = 18), Meng (n = 17), and Emerson (n = 15). Most The largest share of articles on HEV was contributed by United States of America (n = 49) with 12,795 citations. The National Institute of Allergy andInfectious Diseases was leading institute with greatest number of publications (n = 16), cited 3,950 times., Conclusions: The studies conducted on HEV have increased over time. The information presented would be very useful in decision making for policy makers providing health care, and for academicians in providing a reference point for future research.

Competing Interests: Conflict of interest The Author declares that there is no conflict of interest.

To date, SARS-CoV-2 (the virus that causes COVID-19) has spread to almost every region of the world, infecting millions and resulting in the deaths of hundreds of thousands of people. Although it was predicted that Africa would suffer a massive loss of life due to this pandemic, the number of COVID-19 cases has been relatively low across the continent. Researchers have speculated that several factors may be responsible for this outcome in Africa, including the extensive experience that countries have with infectious diseases and the young median age of their populations. However, it is still important for African countries to adopt aggressive and bold approaches against COVID-19, in case the nature of the pandemic changes. This short review will summarize the status of the outbreak in Africa and propose possible reasons for current trends, as well as discuss interventions aimed at preventing a rapid increase in the number of COVID-19 cases in the future., (Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Aim: Depression during pregnancy is a significant cause of adverse birth outcomes, and its prevalence has increased in recent years. This study aimed to give an updated quantification of the risk of preterm birth (PTB), low birth weight (LBW) and intrauterine growth restriction (IUGR) that is associated with antenatal depression., Method: The search was done in different databases, including Web of Science, Scopus and PubMed, from January 2010 to March 2020, and only English-language articles were considered. We only included studies that assessed depression during pregnancy and those that reported data on antenatal depression with at least one adverse birth outcome (PTB, LBW, or IUGR). The quality of studies was assessed using an adaptation of the Newcastle-Ottawa scale assessment tool. The analysis was conducted using STATA (version 12), pooled effect sizes were calculated using the random-effects model and heterogeneity was tested for using the I 2 statistic., Results: The analysis included 23 studies of PTB, LBW and IUGR. There was a significant risk of PTB (RR = 1.35, 95% CI 1.19-1.52), LBW (RR = 1.86, 95% CI 1.32-2.62) and IUGR (RR = 4.39, 95% CI 2.45-7.86). Control for confounders, time of assessing depression, among others altered the risk of LBW due to depression. In addition, depressed women in developing countries had a higher risk of PTB (RR = 2.07, 95% CI 1.13-3.81)., Conclusion: This study identifies a significant risk of PTB, LBW and IUGR due to antennal depression and recognises a need for targeted preventive interventions such as prompt screening to improve and promote maternal mental health care., (Copyright © 2020. Published by Elsevier B.V.)

To understand the epidemiology, evolutionary and transmission characteristics of HIV-1 CRF07&#95;BC in Nanjing, China. One hundred and fifty-nine patients with HIV-1 CRF07&#95;BC were recruited. DNA sequencing, phylogenetic analysis, and molecular transmission cluster analysis were conducted to determine the molecular epidemiology and evolutionary characteristics. Of these HIV-1-infected patients, 95.6% were male, and men who sex with men (76.7%) were the main transmission route. Only 34.0% of these cases were born in Nanjing, and most of them (64.8%) reported having multiple sex partners in the last 6 months. The maximum likelihood phylogenetic analyses of HIV-1 CRF07&#95;BC revealed two lineages. Overall, 67.3% of Nanjing sequences were connected to at least one other individual distributed in 11 clusters, and the average degree was 21.2 with range (1-178). The clustered patients were more likely to be male. The time to a most recent common ancestor for the early HIV-1 CRF07&#95;BC circulating in Nanjing was estimated to be 1998.71[1997.36-2001.07]. The mean estimated evolutionary rate for the epidemic cluster was slightly lower at 2.38[2.12-2.65]  ×  10 -3 per site per year with the relaxed exponential clock model. HIV-1 CRF07&#95;BC was transmitted into Nanjing more than 20 years ago from Yunnan and has become one of the most predominant subtypes with a higher evolutionary rate than before., (© 2020 Wiley Periodicals, Inc.)

Objective: The rise of zoonotic diseases has become a global health issue around the world. The present study is aimed at assessing the global status and the trends in scrub typhus (ST) research., Methods: Publications related to ST studies from 1945 to 21 st July 2020 were retrieved from the Scopus database. The search for the ST literature was conducted using the entry terms of the MeSH (Medical Subject Headings) database. Full research articles and reviews were included in the analysis, and no limitation to the language was specified. Key bibliometric indicator analysis was performed using Microsoft Excel, Bibliometrix (an R package), GraphPad Prism 5, and VOSviewer (version 1.6.6)., Results: A total of 1567 publications were retrieved. The results revealed a significant increase in the number of ST publications over time. The documents received an average of 11.22 citations per document. Mahidol University in Thailand (258, 16.46%) was the most productive institution, while the American Journal of Tropical Medicine and Hygiene published the most ST articles (88, 5.62%). Korea (195, 12.44%) was the most productive country, followed by India (178, 11.36%) and China (106, 6.76%). Richards AL was the most productive author with 36 articles., Conclusions: The study findings provide useful insights into the global efforts and works related to the progress of ST research, which can be used to identify future research areas, such as vaccine development., Competing Interests: The authors declare that they have no conflicts of interest., (Copyright © 2020 Taha Hussein Musa et al.)