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371 results on '"Murthy, S. Narasimha"'

19. Evaluating the Impact of Fatty Alcohols on Permeation of Clotrimazole from Topical Creams: Study results indicate that fatty alcohols may plausibly enhance the skin permeation of clotrimazole

Author

Bhide, Supriya, Panda, Apoorva, Rangappa, S., Repka, M.A., Prado, Rosa Maria Badani, Kundu, S., Richardson, Norman, and Murthy, S. Narasimha

Subjects
Academic Press Inc., Book publishing, Skin, Alcohols, Clotrimazole, Business, Pharmaceuticals and cosmetics industries
Abstract

Pharmaceutical creams are one of the most common types of formulations used for the topical deliver f drugs. Creams are either oil in water (o/w/) or water in oil (w/o) [...]

Published
2020

23. Overcoming challenges in dermal and transdermal delivery of herbal therapeutics with polymeric microneedles.

Author

V. M., Anusha, Suresh, Sarasija, Kumar, Avichal, K., Paranjyothy, N. M., Reena, Rangappa, Srinath, Murthy, S. Narasimha, and H.N., Shivakumar

Abstract

Natural products are generally preferred medications owing to their low toxicity and irritancy potential. However, a good number of herbal therapeutics (HT) exhibit solubility, permeability and stability issues that eventually affect oral bioavailability. Transdermal administration has been successful in resolving some of these issues which has lead in commercialization of a few herbal transdermal products. Polymeric Microneedles (MNs) has emerged as a promising platform in transdermal delivery of HT that face problems in permeating the skin. Several biocompatible and biodegradable polymers used in the fabrication of MNs have been discussed. MNs have been exploited for cutaneous delivery of HT in management of skin ailments like skin cancer, acne, chronic wounds and hypertrophic scar. Considering the clinical need, MNs are explored for systemic delivery of potent HT for management of diverse disorders like asthma, disorders of central nervous system and nicotine replacement as it obviates first pass metabolism and elicits a quicker onset of therapeutic response. MNs of HT have found good number of aesthetic applications in topical delivery of HT to the skin. Interestingly, MNs have emerged as an attractive option as a minimally invasive diagnostic aid in sampling biomarkers from plants, skin and ocular interstitial fluid. The review updates the progress made by MN technology of HT for multiple therapeutic interventions along with the future challenges. An attempt is made to illustrate the challenging formulation strategies employed in the fabrication of polymeric MNs of HT. Efforts are on to extend the potential applications of polymeric MNs to HT for diverse therapeutic applications. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Sublimation of Drugs from the Site of Application of Topical Products

Author

S.G., Pragathi, primary, Echanur, Anusha V, additional, Matadh, Anusha V, additional, Rangappa, Srinath, additional, H.N., Shivakumar, additional, Murthy, Reena N, additional, V.S., Ranganath, additional, Ureña-Benavides, Esteban E., additional, Maibach, Howard, additional, and Murthy, S. Narasimha, additional

Published
2023
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38. Stability of Vaccines

Author

Dumpa, N., Goel, K., Guo, Yuhan, McFall, H., Pillai, Amit Raviraj, Shukla, Ashay, Repka, M. A., and Murthy, S. Narasimha

Published
2019
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