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4. Regulatory Institutions and Policies

Author

Grace, Martin F., Klein, Robert W., Kleindorfer, Paul R., Murray, Michael R., Crew, Michael A., editor, Grace, Martin F., Klein, Robert W., Kleindorfer, Paul R., and Murray, Michael R.

Published
2003
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7. Introduction

Author

Grace, Martin F., Klein, Robert W., Kleindorfer, Paul R., Murray, Michael R., Crew, Michael A., editor, Grace, Martin F., Klein, Robert W., Kleindorfer, Paul R., and Murray, Michael R.

Published
2003
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9. Summary and Conclusions

Author

Grace, Martin F., Klein, Robert W., Kleindorfer, Paul R., Murray, Michael R., Crew, Michael A., editor, Grace, Martin F., Klein, Robert W., Kleindorfer, Paul R., and Murray, Michael R.

Published
2003
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12. Rural Development in Northern Ireland: Policy Formulation in a Peripheral Region of the European Community.

Author

Murray, Michael R. and Greer, John V.

Abstract

Reviews local, national, and European Community influences on the formation of "integrated" rural development policy in Northern Ireland. Suggests three key issues on the policy formation agenda: agricultural versus more diversified programs as the basis of development, implementation problems, and education and training needs. Contains 43 references. (SV)

Published
1992

14. Catastrophe Insurance

Author

Grace, Martin F., primary, Klein, Robert W., additional, Kleindorfer, Paul R., additional, and Murray, Michael R., additional

Published
2003
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16. The property/casualty insurance industry: its past and prospects

Author

Murray, Michael R.

Subjects
Property and casualty insurance -- Economic aspects, Business, Economics, Economic aspects
Abstract

PROPERTY/CASUALTY insurance is an essential cornerstone of commerce. Much of the American economy would grind to a halt without affordable insurance. Many factories, stores, and offices could not face the [...]

Published
1993

19. Changing rules call for improved biosolids phosphorus management

Author

Murray, Michael R., Clark, David L., and Moen, Greg

Subjects
Phosphorus metabolism -- Management, Sewage sludge -- Environmental aspects, Company business management, Business, Business, international, Engineering and manufacturing industries, Environmental services industry
Abstract

With growing concerns regarding the impacts of phosphorus-rich biosolids on land applications, a renewed focus on phosphorus chemistry and how various treatment technologies can be used to reduce these impacts [...]

Published
2004

21. Myocardial drug distribution generated from local epicardial application: Potential impact of cardiac capillary perfusion in a swine model using epinephrine

Author

Massachusetts Institute of Technology. Institute for Medical Engineering & Science, Harvard University--MIT Division of Health Sciences and Technology, Edelman, Elazer R., Groothuis, Adam R., Maslov, Mikhail Y., Pezone, Matthew J., Wei, Abraham E., Wakim, Matthew G., Murray, Michael R., Tsukada, Hisashi, Gerogiannis, Iraklis S., Lovich, Mark A., Edelman, Elazer R, Massachusetts Institute of Technology. Institute for Medical Engineering & Science, Harvard University--MIT Division of Health Sciences and Technology, Edelman, Elazer R., Groothuis, Adam R., Maslov, Mikhail Y., Pezone, Matthew J., Wei, Abraham E., Wakim, Matthew G., Murray, Michael R., Tsukada, Hisashi, Gerogiannis, Iraklis S., Lovich, Mark A., and Edelman, Elazer R

Abstract

Prior studies in small mammals have shown that local epicardial application of inotropic compounds drives myocardial contractility without systemic side effects. Myocardial capillary blood flow, however, may be more significant in larger species than in small animals. We hypothesized that bulk perfusion in capillary beds of the large mammalian heart not only enhances drug distribution after local release, but also clears more drug from the tissue target than in small animals. Epicardial (EC) drug releasing systems were used to apply epinephrine to the anterior surface of the left heart of swine in either point-sourced or distributed configurations. Following local application or intravenous (IV) infusion at the same dose rates, hemodynamic responses, epinephrine levels in the coronary sinus and systemic circulation, and drug deposition across the ventricular wall, around the circumference and down the axis, were measured. EC delivery via point-source release generated transmural epinephrine gradients directly beneath the site of application extending into the middle third of the myocardial thickness. Gradients in drug deposition were also observed down the length of the heart and around the circumference toward the lateral wall, but not the interventricular septum. These gradients extended further than might be predicted from simple diffusion. The circumferential distribution following local epinephrine delivery from a distributed source to the entire anterior wall drove drug toward the inferior wall, further than with point-source release, but again, not to the septum. This augmented drug distribution away from the release source, down the axis of the left ventricle, and selectively toward the left heart follows the direction of capillary perfusion away from the anterior descending and circumflex arteries, suggesting a role for the coronary circulation in determining local drug deposition and clearance. The dominant role of the coronary vasculature is further sugge, American Heart Association (09SDG2060320), Society for Cardiovascular Anesthesiologists (Starter Grant), National Institutes of Health (U.S.) (NIH grant R01 GM-49039), Deshpande Center for Technological Innovation

Published
2016

27. Inhaled Nitric Oxide Augments Left Ventricular Assist Device Capacity by Ameliorating Secondary Right Ventricular Failure

Author

Lovich, Mark A., primary, Pezone, Matthew J., additional, Wakim, Matthew G., additional, Denton, Ryan J., additional, Maslov, Mikhail Y., additional, Murray, Michael R., additional, Tsukada, Hisashi, additional, Agnihotri, Arvind K., additional, Roscigno, Robert F., additional, Gamero, Lucas G., additional, and Gilbert, Richard J., additional

Published
2015
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32. NITRIC OXIDE TREATMENT OF RV FAILURE ASSOCIATED WITH THE USE OF A LEFT VENTRICULAR ASSIST DEVICE AND HYPOXEMIA-INDUCED PULMONARY HYPERTENSION

Author

Lovich, Mark A., primary, Wakim, Mathew G., additional, Maslov, Mikhail Y., additional, Murray, Michael R., additional, Pezone, Mathew J., additional, Tsukada, Hisashi, additional, Agnihotri, Arvind K., additional, Denton, Ryan J., additional, Gamero, Lucas G., additional, Vasquez, Gregory B., additional, Johnson, Bryan J., additional, Roscigno, Robert F., additional, and Richard, Gilbert J., additional

Published
2013
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43. Interactive Strategic Planning and Community Development: The Northern Ireland Experience.

Author

Murray, Michael R. and Greer, John V.

Abstract

This paper discusses a model of community development practice that involves an interactive relationship between organized rural residents and outside technical facilitators. A central argument is that a strategic plan in a multi-community planning situation benefits from a series of specific community development inputs. The discussion draws upon a case study in Northern Ireland where, in a deeply divided society, community-led rural development not only contributes to social and economic change, but also helps promote mutual understanding and reconciliation between contesting cultural traditions. The paper identifies three key issues of wider interest: engaging in strategic planning, supporting multi-community activity, and forging new partnership arrangements. It points to some mechanisms for replication elsewhere. [ABSTRACT FROM PUBLISHER]

Published
1998
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45. Improving quality with a high-risk spine protocol.

Author

Murray, Michael R. and Schafer, Michael F.

Subjects
*MEDICAL protocols, *SPINAL surgery, *PREOPERATIVE risk factors, *HOSPITALS, *NURSES, *ANESTHESIOLOGY
Abstract

The article reports on the development of a protocol by the Northwestern Memorial Hospital in 2011. to minimize the operative risks of orthopaedic spine surgery. The first part of the protocol is aimed to define which patients are regarded high risk and both medical and surgical risk factors are assessed. Nursing staff and anesthesiology have been trained in the protocol and took an active role to educate others about the initiative.

Published
2011

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