1. Defining tic severity and tic impairment in Tourette Disorder
- Author
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McGuire, Joseph F, Piacentini, John, Storch, Eric A, Ricketts, Emily J, Woods, Douglas W, Peterson, Alan L, Walkup, John T, Wilhelm, Sabine, Ramsey, Kesley, Essoe, Joey K-Y, Himle, Michael B, Lewin, Adam B, Chang, Susanna, Murphy, Tanya K, McCracken, James T, and Scahill, Lawrence
- Subjects
Clinical and Health Psychology ,Biomedical and Clinical Sciences ,Psychology ,Tourette Syndrome ,Brain Disorders ,Neurodegenerative ,Clinical Research ,Mental Health ,Humans ,Severity of Illness Index ,Tic Disorders ,Tics ,Tourette disorder ,YGTSS ,Tic severity ,Impairment ,Clinical severity ,Assessment ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Psychiatry ,Clinical sciences ,Clinical and health psychology - Abstract
ObjectiveTreatment guidelines for Tourette's Disorder (TD) are based on patients' degree of tic severity and impairment. However, clear benchmarks for determining tic severity and impairment have not been established. This study examined benchmarks of tic severity and tic impairment using the Yale Global Tic Severity Scale (YGTSS) and the Clinical Global Impression of Severity (CGI-S).MethodIndividuals with TD or another Tic Disorder (N = 519) recruited across nine sites were administered a diagnostic interview, the YGTSS, and the CGI-S. Correlations and trend analyses contrasted YGTSS scores across CGI-S ratings. A logistic regression model examined predictive benchmarks for tic severity, tic impairment, and global severity. Model classifications were compared against CGI-S ratings, and agreement was examined using kappa.ResultsSpearman correlations between the CGI-S and YGTSS scores ranged from 0.54 to 0.63 (p
- Published
- 2021