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1. Voice assistant integrated with augmented reality

Author

Varun Das, G., Srivarsh, S., Murali, E., Fournier-Viger, Philippe, Series Editor, Visvam Devadoss, Ambeth Kumar, editor, Subramanian, Malathi, editor, Emilia Balas, Valentina, editor, Turjman, Fadi Al, editor, and Malaichamy, Ramakrishnan, editor

Published
2024
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5. Approaches to Overcome Human Limitations by an Intelligent Autonomous System with a Level of Consciousness in Reasoning, Decision Making and Problem-Solving Capabilities

Author

Mirriam, A. Jemshia, Rajashree, S., Muneera, M. Nafees, Saranya, V., Murali, E., Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Shaw, Rabindra Nath, editor, Paprzycki, Marcin, editor, and Ghosh, Ankush, editor

Published
2023
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6. Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

Author

Abel, K, Adamali, H, Adeloye, D, Adeyemi, O, Adeyemi, F, Ahmad, S, Ahmed, R, Ainsworth, M, Al-Sheklly, B, Alamoudi, A, Aljaroof, M, Allan, L, Allen, R, Alli, A, Altmann, D, Anderson, D, Andrews, M, Angyal, A, Antoniades, C, Arbane, G, Armour, C, Armstrong, N, Armstrong, L, Arnold, H, Arnold, D, Ashworth, M, Ashworth, A, Assefa-Kebede, H, Atkin, P, Atkins, H, Atkins, A, Aul, R, Avram, C, Baggott, R, Baguley, D, Baillie, J K, Bain, S, Bakali, M, Bakau, M, Baldry, E, Baldwin, D, Ballard, C, Bambrough, J, Barker, R E, Barratt, S, Barrett, F, Basire, D, Basu, N, Batterham, R, Baxendale, H, Bayes, H, Bayley, M, Beadsworth, M, Beirne, P, Bell, R, Bell, D, Berry, C, Betts, S, Bhui, K, Bishop, L, Blaikely, J, Bloomfield, C, Bloss, A, Bolger, A, Bolton, C E, Bonnington, J, Botkai, A, Bourne, M, Bourne, C, Bradley, E, Bramham, K, Brear, L, Breen, G, Breeze, J, Briggs, A, Bright, E, Brightling, C E, Brill, S, Brindle, K, Broad, L, Broome, M, Brown, J S, Brown, M, Brown, J, Brown, R, Brown, V, Brown, A, Brugha, T, Brunskill, N, Buch, M, Bularga, A, Bullmore, E, Burn, D, Burns, G, Busby, J, Buttress, A, Byrne, S, Cairns, P, Calder, P C, Calvelo, E, Card, B, Carr, L, Carson, G, Carter, P, Cavanagh, J, Chalder, T, Chalmers, J D, Chambers, R C, Channon, K, Chapman, K, Charalambou, A, Chaudhuri, N, Checkley, A, Chen, J, Chetham, L, Chilvers, E R, Chinoy, H, Chong-James, K, Choudhury, N, Choudhury, G, Chowdhury, P, Chowienczyk, P, Christie, C, Clark, D, Clark, C, Clarke, J, Clift, P, Clohisey, S, Coburn, Z, Cole, J, Coleman, C, Connell, D, Connolly, B, Connor, L, Cook, A, Cooper, B, Coupland, C, Craig, T, Crisp, P, Cristiano, D, Crooks, M G, Cross, A, Cruz, I, Cullinan, P, Daines, L, Dalton, M, Dark, P, Dasgin, J, David, A, David, C, Davies, M, Davies, G, Davies, K, Davies, F, Davies, G A, Daynes, E, De Silva, T, De Soyza, A, Deakin, B, Deans, A, Defres, S, Dell, A, Dempsey, K, Dennis, J, Dewar, A, Dharmagunawardena, R, Diar Bakerly, N, Dipper, A, Diver, S, Diwanji, S N, Dixon, M, Djukanovic, R, Dobson, H, Dobson, C, Dobson, S L, Docherty, A B, Donaldson, A, Dong, T, Dormand, N, Dougherty, A, Dowling, R, Drain, S, Dulawan, P, Dunleavy, A, Dunn, S, Easom, N, Echevarria, C, Edwards, S, Edwardson, C, Elliott, B, Elliott, A, Ellis, Y, Elmer, A, Elneima, O, Evans, R A, Evans, J, Evans, H, Evans, D, Evans, R I, Evans, R, Evans, T, Fabbri, L, Fairbairn, S, Fairman, A, Fallon, K, Faluyi, D, Favager, C, Felton, T, Finch, J, Finney, S, Fisher, H, Fletcher, S, Flockton, R, Foote, D, Ford, A, Forton, D, Francis, R, Francis, S, Francis, C, Frankel, A, Fraser, E, Free, R, French, N, Fuld, J, Furniss, J, Garner, L, Gautam, N, Geddes, J R, George, P M, George, J, Gibbons, M, Gilmour, L, Gleeson, F, Glossop, J, Glover, S, Goodman, N, Gooptu, B, Gorsuch, T, Gourlay, E, Greenhaff, P, Greenhalf, W, Greenhalgh, A, Greening, N J, Greenwood, J, Greenwood, S, Gregory, R, Grieve, D, Gummadi, M, Gupta, A, Gurram, S, Guthrie, E, Hadley, K, Haggar, A, Hainey, K, Haldar, P, Hall, I, Hall, L, Halling-Brown, M, Hamil, R, Hanley, N A, Hardwick, H E, Hardy, E, Hargadon, B, Harrington, K, Harris, V, Harrison, E M, Harrison, P, Hart, N, Harvey, A, Harvey, M, Harvie, M, Havinden-Williams, M, Hawkes, J, Hawkings, N, Haworth, J, Hayday, A, Heaney, L G, Heeney, J L, Heightman, M, Heller, S, Henderson, M, Hesselden, L, Hillman, T, Hingorani, A, Hiwot, T, Ho, L P, Hoare, A, Hoare, M, Hogarth, P, Holbourn, A, Holdsworth, L, Holgate, D, Holmes, K, Holroyd-Hind, B, Horsley, A, Hosseini, A, Hotopf, M, Houchen, L, Howard, L, Howell, A, Hufton, E, Hughes, A, Hughes, J, Hughes, R, Humphries, A, Huneke, N, Hurst, J R, Hurst, R, Husain, M, Hussell, T, Ibrahim, W, Ient, A, Ingram, L, Ismail, K, Jackson, T, Jacob, J, James, W Y, Janes, S, Jarvis, H, Jayaraman, B, Jenkins, R G, Jezzard, P, Jiwa, K, Johnson, S, Johnson, C, Johnston, D, Jolley, C, Jolley, C J, Jones, I, Jones, S, Jones, D, Jones, H, Jones, G, Jones, M, Jose, S, Kabir, T, Kaltsakas, G, Kamwa, V, Kar, P, Kausar, Z, Kelly, S, Kerr, S, Key, A L, Khan, F, Khunti, K, King, C, King, B, Kitterick, P, Klenerman, P, Knibbs, L, Knight, S, Knighton, A, Kon, O M, Kon, S, Kon, S S, Korszun, A, Kotanidis, C, Koychev, I, Kurupati, P, Kwan, J, Laing, C, Lamlum, H, Landers, G, Langenberg, C, Lasserson, D, Lawrie, A, Lea, A, Leavy, O C, Lee, D, Lee, E, Leitch, K, Lenagh, R, Lewis, K, Lewis, V, Lewis, K E, Lewis, J, Lewis-Burke, N, Light, T, Lightstone, L, Lim, L, Linford, S, Lingford-Hughes, A, Lipman, M, Liyanage, K, Lloyd, A, Logan, S, Lomas, D, Lone, N I, Loosley, R, Lord, J M, Lota, H, Lucey, A, MacGowan, G, Macharia, I, Mackay, C, Macliver, L, Madathil, S, Madzamba, G, Magee, N, Mairs, N, Majeed, N, Major, E, Malim, M, Mallison, G, Man, W, Mandal, S, Mangion, K, Mansoori, P, Marciniak, S, Mariveles, M, Marks, M, Marshall, B, Martineau, A, Maskell, N, Matila, D, Matthews, L, Mayet, J, McAdoo, S, McAllister-Williams, H, McArdle, P, McArdle, A, McAulay, D, McAuley, H J C, McAuley, D F, McCafferty, K, McCann, G P, McCauley, H, McCourt, P, Mcgarvey, L, McGinness, J, McGovern, A, McGuinness, H, McInnes, I B, McIvor, K, McIvor, E, McMahon, A, McMahon, M J, McMorrow, L, Mcnally, T, McNarry, M, McQueen, A, McShane, H, Megson, S, Meiring, J, Menzies, D, Michael, A, Michael, B D, Milligan, L, Mills, N, Mitchell, J, Mohamed, A, Molyneaux, P L, Monteiro, W, Morley, A, Morrison, L, Morriss, R, Morrow, A, Moss, A, Moss, A J, Moss, P, Mukaetova-Ladinska, E, Munawar, U, Murali, E, Murira, J, Nassa, H, Neill, P, Neubauer, S, Newby, D, Newell, H, Newton Cox, A, Nicholson, T, Nicoll, D, Nolan, C M, Noonan, M J, Novotny, P, Nunag, J, Nyaboko, J, O'Brien, L, Odell, N, Ogg, G, Olaosebikan, O, Oliver, C, Omar, Z, Openshaw, P J M, Osbourne, R, Ostermann, M, Overton, C, Oxton, J, Pacpaco, E, Paddick, S, Papineni, P, Paradowski, K, Pareek, M, Parekh, D, Parfrey, H, Pariante, C, Parker, S, Parkes, M, Parmar, J, Parvin, R, Patale, S, Patel, B, Patel, S, Patel, M, Pathmanathan, B, Pavlides, M, Pearl, J E, Peckham, D, Pendlebury, J, Peng, Y, Pennington, C, Peralta, I, Perkins, E, Peto, T, Petousi, N, Petrie, J, Pfeffer, P, Phipps, J, Pimm, J, Piper Hanley, K, Pius, R, Plein, S, Plekhanova, T, Poinasamy, K, Polgar, O, Poll, L, Porter, J C, Portukhay, S, Powell, N, Price, L, Price, D, Price, A, Price, C, Prickett, A, Quaid, S, Quigley, J, Quint, J, Qureshi, H, Rahman, N, Rahman, M, Ralser, M, Raman, B, Ramos, A, Rangeley, J, Rees, T, Regan, K, Richards, A, Richardson, M, Rivera-Ortega, P, Robertson, E, Rodgers, J, Ross, G, Rossdale, J, Rostron, A, Routen, A, Rowland, A, Rowland, M J, Rowland, J, Rowland-Jones, S L, Roy, K, Rudan, I, Russell, R, Russell, E, Sabit, R, Sage, E K, Samani, N, Samuel, R, Sapey, E, Saralaya, D, Saratzis, A, Sargeant, J, Sass, T, Sattar, N, Saunders, K, Saunders, R, Saxon, W, Sayer, A, Schwaeble, W, Scott, J, Scott, K, Selby, N, Semple, M G, Sereno, M, Shah, K, Shah, A, Shah, P, Sharma, M, Sharpe, M, Sharpe, C, Shaw, V, Sheikh, A, Shevket, K, Shikotra, A, Short, J, Siddiqui, S, Sigfrid, L, Simons, G, Simpson, J, Singapuri, A, Singh, S J, Singh, C, Singh, S, Skeemer, J, Smith, I, Smith, J, Smith, L, Smith, A, Soares, M, Southern, D, Spears, M, Spencer, L G, Speranza, F, Stadon, L, Stanel, S, Steiner, M, Stensel, D, Stern, M, Stewart, I, Stockley, J, Stone, R, Storrie, A, Storton, K, Stringer, E, Subbe, C, Sudlow, C, Suleiman, Z, Summers, C, Summersgill, C, Sutherland, D, Sykes, D L, Sykes, R, Talbot, N, Tan, A L, Taylor, C, Taylor, A, Te, A, Tedd, H, Tee, C J, Tench, H, Terry, S, Thackray-Nocera, S, Thaivalappil, F, Thickett, D, Thomas, D, Thomas, D C, Thomas, A K, Thompson, A A R, Thompson, T, Thornton, T, Thwaites, R S, Tobin, M, Toingson, G F, Tong, C, Toshner, M, Touyz, R, Tripp, K A, Tunnicliffe, E, Turner, E, Turtle, L, Turton, H, Ugwuoke, R, Upthegrove, R, Valabhji, J, Vellore, K, Wade, E, Wain, L V, Wajero, L O, Walder, S, Walker, S, Wall, E, Wallis, T, Walmsley, S, Walsh, S, Walsh, J A, Watson, L, Watson, J, Watson, E, Welch, C, Welch, H, Welsh, B, Wessely, S, West, S, Wheeler, H, Whitehead, V, Whitney, J, Whittaker, S, Whittam, B, Wild, J, Wilkins, M, Wilkinson, D, Williams, N, Williams, B, Williams, J, Williams-Howard, S A, Willicombe, M, Willis, G, Wilson, D, Wilson, I, Window, N, Witham, M, Wolf-Roberts, R, Woodhead, F, Woods, J, Wootton, D, Worsley, J, Wraith, D, Wright, L, Wright, C, Wright, S, Xie, C, Yasmin, S, Yates, T, Yip, K P, Young, B, Young, S, Young, A, Yousuf, A J, Yousuf, A, Zawia, A, Zhao, B, Zongo, O, Evans, Rachael A, McAuley, Hamish J C, Harrison, Ewen M, Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Elneima, Omer, Docherty, Annemarie B, Lone, Nazir I, Leavy, Olivia C, Daines, Luke, Baillie, J Kenneth, Brown, Jeremy S, Chalder, Trudie, De Soyza, Anthony, Diar Bakerly, Nawar, Easom, Nicholas, Geddes, John R, Greening, Neil J, Hart, Nick, Heaney, Liam G, Heller, Simon, Howard, Luke, Hurst, John R, Jacob, Joseph, Jenkins, R Gisli, Jolley, Caroline, Kerr, Steven, Kon, Onn M, Lewis, Keir, Lord, Janet M, McCann, Gerry P, Neubauer, Stefan, Openshaw, Peter J M, Parekh, Dhruv, Pfeffer, Paul, Rahman, Najib M, Raman, Betty, Richardson, Matthew, Rowland, Matthew, Semple, Malcolm G, Shah, Ajay M, Singh, Sally J, Sheikh, Aziz, Thomas, David, Toshner, Mark, Chalmers, James D, Ho, Ling-Pei, Horsley, Alex, Marks, Michael, Poinasamy, Krisnah, Wain, Louise V, and Brightling, Christopher E

Published
2021
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8. Personal identification using human ear recognition system.

Author

Vignesh, R., Sivasangari, S., Deepa, D., Murali, E., Hemalatha, S., and Priyanka, N.

Subjects
IDENTIFICATION, EAR, FACIAL expression
Abstract

In measurable and civilian applications, multibiometric arrays with facial and ear sensors are increasingly being implemented to overcome facial expression and occlusion posture issues. Various ear and collision detection methods have been proposed and much work has been done, but the areas are 3D data localization and 3D ear detection. This paper captures 3D ears under an unusual type of yaw. This yaw can be performed naked or in the right ear without prior knowledge of ear area strategies, identifiable ear signs, and prior posture. Displays posture classification based on. [ABSTRACT FROM AUTHOR]

Published
2024
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13. An Ontology-based Knowledge Mining Model for Effective Exploitation of Agro Information.

Author

Murali, E. and Anouncia, S. Margret

Subjects
*KNOWLEDGE representation (Information theory), *SOIL mineralogy, *CROP quality, *WATER supply, *CROP yields, *COMPUTER software reusability, *AGRICULTURAL technology
Abstract

The quality of agriculture depends on the quality of the yield, which is usually obtained through the well-being of the crop. The quality of any crop depends on the minerals in the soil, the type of soil, the location, and the seasons. The crop yield depends on soil fertility, availability of water, climate, and disease prevention. Although this information is prevailing in plenty among the expert farmers, the means of abducting the information to the future generation has not been much promoted. Hence, the knowledge disseminated regarding agriculture becomes scarce, affecting the entire agricultural process. Given these facts, a single source, strong knowledge management system is proposed to be designed. The system aims to embrace the different kinds of knowledge associated with agriculture and attempt to obtain a single source of agro information that is very much usable and reusable to the users. To ensure the maximum level of reusability, the knowledge of the domain needs to be modeled and represented in a way that is scalable and flexible. One of the knowledge representation techniques that emphasizes on reusability and scalability is ontology. Thus, this paper attempts to design an ontology-based agro knowledge management system. A rule base is constructed to improve the expressiveness of the knowledge. An incremental mining approach is adopted to extract the knowledge from multiple ontology. To understand better to aid decision-making, a visualization task is carried out. A multi ontology-based knowledge mining model is attempted in this research to provide better insight regarding agro knowledge. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

Author

Evans, Rachael A, primary, McAuley, Hamish, additional, Harrison, Ewen M, additional, Shikotra, Aarti, additional, Singapuri, Amisha, additional, Sereno, Marco, additional, Elneima, Omer, additional, Docherty, Annemarie B, additional, Lone, Nazir I, additional, Leavy, Olivia C, additional, Daines, Luke, additional, Baillie, J Kenneth, additional, Brown, Jeremy S, additional, Chalder, Trudie, additional, De Soyza, Anthony, additional, Diar Bakerly, Nawar, additional, Easom, Nicholas, additional, Geddes, John R, additional, Greening, Neil J, additional, Hart, Nick, additional, Heaney, Liam G, additional, Heller, Simon, additional, Howard, Luke, additional, Hurst, John R, additional, Jacob, Joseph, additional, Jenkins, R Gisli, additional, Jolley, Caroline, additional, Kerr, Steven, additional, Kon, Onn M, additional, Lewis, Keir, additional, Lord, Janet M, additional, McCann, Gerry P, additional, Neubauer, Stefan, additional, Openshaw, Peter J M, additional, Parekh, Dhruv, additional, Pfeffer, Paul, additional, Rahman, Najib M, additional, Raman, Betty, additional, Richardson, Matthew, additional, Rowland, Matthew, additional, Semple, Malcolm G, additional, Shah, Ajay M, additional, Singh, Sally J, additional, Sheikh, Aziz, additional, Thomas, David, additional, Toshner, Mark, additional, Chalmers, James D, additional, Ho, Ling-Pei, additional, Horsley, Alex, additional, Marks, Michael, additional, Poinasamy, Krisnah, additional, Wain, Louise V, additional, Brightling, Christopher E, additional, Abel, K, additional, Adamali, H, additional, Adeloye, D, additional, Adeyemi, O, additional, Adeyemi, F, additional, Ahmad, S, additional, Ahmed, R, additional, Ainsworth, M, additional, Alamoudi, A, additional, Aljaroof, M, additional, Allan, L, additional, Allen, R, additional, Alli, A, additional, Al-Sheklly, B, additional, Altmann, D, additional, Anderson, D, additional, Andrews, M, additional, Angyal, A, additional, Antoniades, C, additional, Arbane, G, additional, Armour, C, additional, Armstrong, N, additional, Armstrong, L, additional, Arnold, H, additional, Arnold, D, additional, Ashworth, M, additional, Ashworth, A, additional, Assefa-Kebede, H, additional, Atkin, P, additional, Atkins, H, additional, Atkins, A, additional, Aul, R, additional, Avram, C, additional, Baggott, R, additional, Baguley, D, additional, Baillie, J K, additional, Bain, S, additional, Bakali, M, additional, Bakau, M, additional, Baldry, E, additional, Baldwin, D, additional, Ballard, C, additional, Bambrough, J, additional, Barker, R E, additional, Barratt, S, additional, Barrett, F, additional, Basu, N, additional, Batterham, R, additional, Baxendale, H, additional, Bayes, H, additional, Bayley, M, additional, Beadsworth, M, additional, Beirne, P, additional, Bell, R, additional, Bell, D, additional, Berry, C, additional, Betts, S, additional, Bhui, K, additional, Bishop, L, additional, Blaikely, J, additional, Bloomfield, C, additional, Bloss, A, additional, Bolger, A, additional, Bolton, C E, additional, Bonnington, J, additional, Botkai, A, additional, Bourne, M, additional, Bourne, C, additional, Bradley, E, additional, Bramham, K, additional, Brear, L, additional, Breen, G, additional, Breeze, J, additional, Briggs, A, additional, Bright, E, additional, Brightling, C E, additional, Brill, S, additional, Brindle, K, additional, Broad, L, additional, Broome, M, additional, Brown, J S, additional, Brown, M, additional, Brown, J, additional, Brown, R, additional, Brown, V, additional, Brown, A, additional, Brugha, T, additional, Brunskill, N, additional, Buch, M, additional, Bularga, A, additional, Bullmore, E, additional, Burn, D, additional, Burns, G, additional, Busby, J, additional, Buttress, A, additional, Byrne, S, additional, Cairns, P, additional, Calder, P C, additional, Calvelo, E, additional, Card, B, additional, Carr, L, additional, Carson, G, additional, Carter, P, additional, Cavanagh, J, additional, Chalder, T, additional, Chalmers, J D, additional, Chambers, R C, additional, Channon, K, additional, Chapman, K, additional, Charalambou, A, additional, Chaudhuri, N, additional, Checkley, A, additional, Chen, J, additional, Chetham, L, additional, Chilvers, E R, additional, Chinoy, H, additional, Chong-James, K, additional, Choudhury, N, additional, Choudhury, G, additional, Chowdhury, P, additional, Chowienczyk, P, additional, Christie, C, additional, Clark, D, additional, Clark, C, additional, Clarke, J, additional, Clift, P, additional, Clohisey, S, additional, Coburn, Z, additional, Cole, J, additional, Coleman, C, additional, Connell, D, additional, Connolly, B, additional, Connor, L, additional, Cook, A, additional, Cooper, B, additional, Coupland, C, additional, Craig, T, additional, Crisp, P, additional, Cristiano, D, additional, Crooks, M G, additional, Cross, A, additional, Cruz, I, additional, Cullinan, P, additional, Daines, L, additional, Dalton, M, additional, Dark, P, additional, Dasgin, J, additional, David, A, additional, David, C, additional, Davies, M, additional, Davies, G, additional, Davies, K, additional, Davies, F, additional, Davies, G A, additional, Daynes, E, additional, De Silva, T, additional, De Soyza, A, additional, Deakin, B, additional, Deans, A, additional, Defres, S, additional, Dell, A, additional, Dempsey, K, additional, Dennis, J, additional, Dewar, A, additional, Dharmagunawardena, R, additional, Diar Bakerly, N, additional, Dipper, A, additional, Diver, S, additional, Diwanji, S N, additional, Dixon, M, additional, Djukanovic, R, additional, Dobson, H, additional, Dobson, C, additional, Dobson, S L, additional, Docherty, A B, additional, Donaldson, A, additional, Dong, T, additional, Dormand, N, additional, Dougherty, A, additional, Dowling, R, additional, Drain, S, additional, Dulawan, P, additional, Dunn, S, additional, Easom, N, additional, Echevarria, C, additional, Edwards, S, additional, Edwardson, C, additional, Elliott, B, additional, Elliott, A, additional, Ellis, Y, additional, Elmer, A, additional, Elneima, O, additional, Evans, R A, additional, Evans, J, additional, Evans, H, additional, Evans, D, additional, Evans, R I, additional, Evans, R, additional, Evans, T, additional, Fabbri, L, additional, Fairbairn, S, additional, Fairman, A, additional, Fallon, K, additional, Faluyi, D, additional, Favager, C, additional, Felton, T, additional, Finch, J, additional, Finney, S, additional, Fisher, H, additional, Fletcher, S, additional, Flockton, R, additional, Foote, D, additional, Ford, A, additional, Forton, D, additional, Francis, R, additional, Francis, S, additional, Francis, C, additional, Frankel, A, additional, Fraser, E, additional, Free, R, additional, French, N, additional, Fuld, J, additional, Furniss, J, additional, Garner, L, additional, Gautam, N, additional, Geddes, J R, additional, George, P M, additional, George, J, additional, Gibbons, M, additional, Gilmour, L, additional, Gleeson, F, additional, Glossop, J, additional, Glover, S, additional, Goodman, N, additional, Gooptu, B, additional, Gorsuch, T, additional, Gourlay, E, additional, Greenhaff, P, additional, Greenhalf, W, additional, Greenhalgh, A, additional, Greening, N J, additional, Greenwood, J, additional, Greenwood, S, additional, Gregory, R, additional, Grieve, D, additional, Gummadi, M, additional, Gupta, A, additional, Gurram, S, additional, Guthrie, E, additional, Hadley, K, additional, Haggar, A, additional, Hainey, K, additional, Haldar, P, additional, Hall, I, additional, Hall, L, additional, Halling-Brown, M, additional, Hamil, R, additional, Hanley, N A, additional, Hardwick, H, additional, Hardy, E, additional, Hargadon, B, additional, Harrington, K, additional, Harris, V, additional, Harrison, E M, additional, Harrison, P, additional, Hart, N, additional, Harvey, A, additional, Harvey, M, additional, Harvie, M, additional, Havinden-Williams, M, additional, Hawkes, J, additional, Hawkings, N, additional, Haworth, J, additional, Hayday, A, additional, Heaney, L G, additional, Heeney, J L, additional, Heightman, M, additional, Heller, S, additional, Henderson, M, additional, Hesselden, L, additional, Hillman, T, additional, Hingorani, A, additional, Hiwot, T, additional, Ho, L P, additional, Hoare, A, additional, Hoare, M, additional, Hogarth, P, additional, Holbourn, A, additional, Holdsworth, L, additional, Holgate, D, additional, Holmes, K, additional, Holroyd-Hind, B, additional, Horsley, A, additional, Hosseini, A, additional, Hotopf, M, additional, Houchen, L, additional, Howard, L, additional, Howell, A, additional, Hufton, E, additional, Hughes, A, additional, Hughes, J, additional, Hughes, R, additional, Humphries, A, additional, Huneke, N, additional, Hurst, J R, additional, Hurst, R, additional, Husain, M, additional, Hussell, T, additional, Ibrahim, W, additional, Ient, A, additional, Ingram, L, additional, Ismail, K, additional, Jackson, T, additional, Jacob, J, additional, James, W Y, additional, Janes, S, additional, Jarvis, H, additional, Jayaraman, B, additional, Jenkins, R G, additional, Jezzard, P, additional, Jiwa, K, additional, Johnson, S, additional, Johnson, C, additional, Johnston, D, additional, Jolley, C, additional, Jolley, C J, additional, Jones, I, additional, Jones, S, additional, Jones, D, additional, Jones, H, additional, Jones, G, additional, Jones, M, additional, Jose, S, additional, Kabir, T, additional, Kaltsakas, G, additional, Kamwa, V, additional, Kar, P, additional, Kausar, Z, additional, Kelly, S, additional, Kerr, S, additional, Key, A L, additional, Khan, F, additional, Khunti, K, additional, King, C, additional, King, B, additional, Kitterick, P, additional, Klenerman, P, additional, Knibbs, L, additional, Knight, S, additional, Knighton, A, additional, Kon, O M, additional, Kon, S, additional, Kon, S S, additional, Korszun, A, additional, Kotanidis, C, additional, Koychev, I, additional, Kurupati, P, additional, Kwan, J, additional, 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Published
2021
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23. H.264 Motion Estimation and Applications

Author

E. Gangadharan, Murali E. Krishnan, and Nirmal P. Kumar

Subjects
Computer science, business.industry, Motion estimation, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Computer vision, Artificial intelligence, business
Published
2012

29. Cell based dATP delivery as a therapy for chronic heart failure.

Author

Mhatre KN, Mathieu J, Martinson A, Flint G, Blakley LP, Tabesh A, Reinecke H, Yang X, Guan X, Murali E, Klaiman JM, Odom GL, Brown MB, Tian R, Hauschka SD, Raftery D, Moussavi-Harami F, Regnier M, and Murry CE

Abstract

Transplanted human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) improve ventricular performance when delivered acutely post-myocardial infarction but are ineffective in chronic myocardial infarction/heart failure. 2'-deoxy-ATP (dATP) activates cardiac myosin and potently increases contractility. Here we engineered hPSC-CMs to overexpress ribonucleotide reductase, the enzyme controlling dATP production. In vivo, dATP-producing CMs formed new myocardium that transferred dATP to host cardiomyocytes via gap junctions, increasing their dATP levels. Strikingly, when transplanted into chronically infarcted hearts, dATP-producing grafts increased left ventricular function, whereas heart failure worsened with wild-type grafts or vehicle injections. dATP-donor cells recipients had greater voluntary exercise, improved cardiac metabolism, reduced pulmonary congestion and pathological cardiac hypertrophy, and improved survival. This combination of remuscularization plus enhanced host contractility offers a novel approach to treating the chronically failing heart., Competing Interests: Competing interests: M.R., C.E.M., K.N.M., and S.D.H. are inventors (University of Washington) on a patent for (US Utility Patent application # PCT/US2023/062377 filed on 10th February 2023). Some of these studies were performed while C.E.M. was an employee of Sana Biotechnology; C.E.M. is also an equity holder in Sana Biotechnology. S.D.H. has a pending patent regarding CK8m promoter. Authors declare that they have no competing interests.

Published
2023
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