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18 results on '"Munk, Ane Cecilie"'

2. HPV self-sampling among long-term non-attenders to cervical cancer screening in Norway: A pragmatic randomized controlled trial

Author

Aasbo, Gunvor, primary, Trope, Ameli, additional, Nygard, Mari, additional, Christiansen, Irene Kraus, additional, Baasland, Ingrid, additional, Iversen, Grete Alrek, additional, Munk, Ane Cecilie, additional, Christiansen, Marit Halonen, additional, Presthus, Gro Kummeneje, additional, Undem, Karina, additional, Bjorge, Tone, additional, Castle, Philip E., additional, and Hansen, Bo T., additional

Published
2022
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5. High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling

Author

Øvestad, Irene Tveiterås, primary, Engesæter, Birgit, additional, Halle, Mari Kyllesø, additional, Akbari, Saleha, additional, Bicskei, Beatrix, additional, Lapin, Morten, additional, Austdal, Marie, additional, Janssen, Emiel A. M., additional, Krakstad, Camilla, additional, Lillesand, Melinda, additional, Nordhus, Marit, additional, Munk, Ane Cecilie, additional, and Gudlaugsson, Einar G., additional

Published
2021
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6. A Gene Signature Identifying CIN3 Regression and Cervical Cancer Survival

Author

Halle, Mari K., primary, Munk, Ane Cecilie, additional, Engesæter, Birgit, additional, Akbari, Saleha, additional, Frafjord, Astri, additional, Hoivik, Erling A., additional, Forsse, David, additional, Fasmer, Kristine E., additional, Woie, Kathrine, additional, Haldorsen, Ingfrid S., additional, Bertelsen, Bjørn I., additional, Janssen, Emiel A. M., additional, Gudslaugsson, Einar, additional, Krakstad, Camilla, additional, and Øvestad, Irene T., additional

Published
2021
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12. Consistent condom use increases spontaneous regression in high-risk non-HPV16 but not in HPV16 CIN2-3 lesions, a prospective population-based cohort study

Author

Munk, Ane Cecilie, primary, Øvestad, Irene Tveiterås, additional, Gudlaugsson, Einar, additional, Løvslett, Kjell, additional, Fiane, Bent, additional, van Diermen-Hidle, Bianca, additional, Kruse, Arnold-Jan, additional, Skaland, Ivar, additional, Janssen, Emiel AM, additional, and Baak, Jan PA, additional

Published
2012
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17. High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling.

Author

Øvestad, Irene Tveiterås, Engesæter, Birgit, Halle, Mari Kyllesø, Akbari, Saleha, Bicskei, Beatrix, Lapin, Morten, Austdal, Marie, Janssen, Emiel A. M., Krakstad, Camilla, Lillesand, Melinda, Nordhus, Marit, Munk, Ane Cecilie, and Gudlaugsson, Einar G.

Subjects
CERVICAL intraepithelial neoplasia, PAPILLOMAVIRUS diseases, PAPILLOMAVIRUSES, RNA sequencing, DISEASE risk factors, CERVICAL cancer, ONCOGENES
Abstract

Implementation of high-risk human papilloma virus (HPV) screening and the increasing proportion of HPV vaccinated women in the screening program will reduce the percentage of HPV positive women with oncogenic potential. In search of more specific markers to identify women with high risk of cancer development, we used RNA sequencing to compare the transcriptomic immune-profile of 13 lesions with cervical intraepithelial neoplasia grade 3 (CIN3) or adenocarcinoma in situ (AIS) and 14 normal biopsies from women with detected HPV infections. In CIN3/AIS lesions as compared to normal tissue, 27 differential expressed genes were identified. Transcriptomic analysis revealed significantly higher expression of a number of genes related to proliferation, (CDKN2A, MELK, CDK1, MKI67, CCNB2, BUB1, FOXM1, CDKN3), but significantly lower expression of genes related to a favorable immune response (NCAM1, ARG1, CD160, IL18, CX3CL1). Compared to the RNA sequencing results, good correlation was achieved with relative quantitative PCR analysis for NCAM1 and CDKN2A. Quantification of NCAM1 positive cells with immunohistochemistry showed epithelial reduction of NCAM1 in CIN3/AIS lesions. In conclusion, NCAM1 and CDKN2A are two promising candidates to distinguish whether women are at high risk of developing cervical cancer and in need of frequent follow-up. [ABSTRACT FROM AUTHOR]

Published
2022
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18. A high-risk delivery patient with COVID-19.

Author

Munk AC, Sagedal LR, Krogedal TS, McFadzean I, and Oommen H

Subjects
Betacoronavirus, COVID-19, Female, Humans, Pregnancy, SARS-CoV-2, Coronavirus Infections, Pandemics, Pneumonia, Viral, Pregnancy Complications, Infectious virology
Published
2020
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