36 results on '"Munawar T"'
Search Results
2. Soil Pollution by Micro- and Nanoplastics: Sources, Fate, and Impact
- Author
-
Surya Prakash, D. V., Gupta, Istuti, Mallu, Maheswara Reddy, Munawar, T. Mohammad, Maddela, Naga Raju, editor, Reddy, Kondakindi Venkateswar, editor, and Ranjit, Pabbati, editor
- Published
- 2023
- Full Text
- View/download PDF
3. Aloe monticola Reynolds: A refugee of the mountains − contributing towards its conservation through in vitro propagation
- Author
-
Berhe, Birhanu Debesay, Sbhatu, Desta Berhe, Munawar, T. Mohammad, and Gebreyohannes, Gebreselama
- Published
- 2023
- Full Text
- View/download PDF
4. Aloe Monticola Reynolds: A Refugee of the Mountains − Contributing Towards its Conservation Through in Vitro Propagation
- Author
-
Sbhatu, Desta Berhe Berhe, primary, Berhe, Birhanu Debesay, additional, Munawar, T. Mohammad, additional, and Gebreyohannes, Gebreselema, additional
- Published
- 2023
- Full Text
- View/download PDF
5. Studies on Cytotoxic and Genotoxic potential of Ethanolic extract of Lawsonia inermis leaves
- Author
-
Munawar T, Mohammad, primary, Rao, Chinta Koteswara, additional, Rajesh, Andanamala Vijay, additional, Sharma, Udit Narayan, additional, Gupta, Istuti, additional, and Surya Prakash, D. V., additional
- Published
- 2022
- Full Text
- View/download PDF
6. Examining the role of family sociology, managerial support, and working conditions in determining teacher performance in Indonesia: the mediating role of motivation and professional development
- Author
-
Maria Ulfah, Husni Syahrudin, Munawar Thoharudin, Sandra Fitria Wardani, and Nur Kholifah
- Subjects
teacher performance ,motivation ,professional development ,family sociology ,managerial support ,working condition ,Education (General) ,L7-991 - Abstract
In developing countries like Indonesia, responsible agencies have yet to consider in-depth factors in building better teacher performance in secondary education. Contemporary educational research has explored the relationship between motivation and professional development on teacher performance. However, there needs to be more understanding of this relationship with family sociological conditions, levels of managerial support, and different working conditions. This research examines how motivation and professional development can determine teacher performance by involving these three conditions. This research involved 474 secondary education teachers voluntarily and with specific criteria profiles tailored to their needs. Data collection was assisted using a closed questionnaire with a four-point Likert scale, tested for validity and reliability. Structural Equation Modeling was used to analyze data through path analysis and bootstrap methods. The findings prove the importance of motivation and professional development supported by family sociological conditions, managerial support, and proportional workload in determining teacher performance. These results shed light on secondary education providers in strengthening professional development and simultaneously strengthening teacher motivation which has so far often been overlooked. The strategy used is to provide support in the managerial aspect to create work comfort and a proportional workload to make it easier for teachers to carry out technical development. Lastly, support and positive relationships from the family contribute to strengthening the teacher’s mentality which leads to strengthening work motivation. In conclusion, teacher performance in secondary education can be optimal by carrying out self-development, strengthening motivation, proportional performance, in addition to managerial and family support in establishing mental health.
- Published
- 2024
- Full Text
- View/download PDF
7. Bioinspired synthesis of zinc oxide nano-flowers: A surface enhanced antibacterial and harvesting efficiency.
- Author
-
Hasan, M, Altaf, M, Zafar, A, Hassan, SG, Ali, Z, Mustafa, G, Munawar, T, Saif, MS, Tariq, T, Iqbal, F, Khan, MW, Mahmood, A, Mahmood, N, Shu, X, Hasan, M, Altaf, M, Zafar, A, Hassan, SG, Ali, Z, Mustafa, G, Munawar, T, Saif, MS, Tariq, T, Iqbal, F, Khan, MW, Mahmood, A, Mahmood, N, and Shu, X
- Abstract
Despite of broad range application, the cost effective, highly stable and reproduceable synthesis of ZnO is needed, especially which can make it biosafe as well. Here, a unique bioinspired synthesis of ZnO nanoflowers (NFs) has been introduced using Withania coagulans extract as reducing agent. Different molar concentrations were assessed to counter the effect of structural, morphological, antibacterial activity and high efficiency of algae harvesting. The UV-spectroscopy authenticates the synthesis of ZnO NFs having Wurtzite hexagonal structure with the size in the range of 360-550 nm. While surface analysis revealed the presence of stabilizing agent like phenolic, amine, etc. on surface of ZnO NFs. These perineum ZnO NFs exhibited a stronger antibacterial with Gram-positive bacteria Staphylococcus aureus as compare to Gram-negative bacteria Pseudomonas aeruginosa and greater harvesting efficiency up to 94% on the account of greater surface area and unique surface chemistry, thus leading a new horizon of more efficient and effective applications for ethanol production.
- Published
- 2021
8. Development of response surface methodology for optimization of parameters and quantitative analysis of chebulinic acid from composition of medicinal herbs by HPLC
- Author
-
Munawar, T. Mohammad, primary, Surya Prakash, D.V., additional, and Vangalapati, Meena, additional
- Published
- 2019
- Full Text
- View/download PDF
9. 03:45 PM Abstract No. 368 Changes in ph and not temperature significantly contributes to cell death during IRE performed at low-voltage and high pulse numbers
- Author
-
Munawar, T., primary, Fujimori, M., additional, Vista, W., additional, Solomon, S., additional, and Srimathveeravalli, G., additional
- Published
- 2019
- Full Text
- View/download PDF
10. Isolation, characterization and identification of contaminant bacteria from sugarcane (Saccharum officinarum L.) in vitro culture.
- Author
-
MUNAWAR, T. MOHAMMAD, REDDA, YISEHAK TSEGAYE, TSEHAYEKIDUS, T., and TEKA, ZENEBE
- Subjects
- *
ANTIBIOTICS , *BACTERIAL diversity , *SENSITIVITY analysis , *PLANT tissue culture , *MICROBIAL contamination - Abstract
Plant tissue cultures can be contaminated by extensive diversity of bacteria and the contamination is specific to species. The contamination leads to decrease in growth rate of shoot, root, multiplication factor and even cause plant death. The study was conducted on old contaminated in vitro sugarcane culture obtained from laboratory of plant tissue culture from June 2017 to May 2018 at Mekelle University, College of Veterinary Medicine and Tigray Biotechnology center in 14 days. The objective of the study was to isolate, characterize and identify bacteria from contaminated in vitro Sugarcane culture and to test the sensitivity of the isolates to the most commonly used antibiotics. In the present study, Escherichia, Bacillus and Micrococcus were isolated and identified as the major contaminant bacteria from in vitro sugarcane cultures. In antibacterial susceptibility test, the isolates of Bacillus and Micrococcus were susceptible to Gentamicin, Chloramphenicol, Ciprofloxaciline, Tetracycline, Vancomycine, Streptomycin, Penicillin G and Kanamycin demonstrating the efficacy of these antimicrobial for the treatment of sugarcane in vitro culture contamination, the third isolate Escherichia were resistance to all antibiotic agents. The multi-drug resistant Escherichia isolated in the current study may be a threat because it may spread to other cultures found in the laboratory. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
11. PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACTS OF TAGETES ERECTA AND ZINGIBER OFFICINALE
- Author
-
Munawar, T. Mohammad, primary
- Published
- 2017
- Full Text
- View/download PDF
12. EVALUATION OF ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACTS OF SALVADORA PERSICA
- Author
-
Munawar, T. Mohammad, primary
- Published
- 2017
- Full Text
- View/download PDF
13. Study of plant resources with ethnomedicinal relevance from district Bagh, Azad Jammu and Kashmir, Pakistan
- Author
-
Maqsood Tasneem, Munawar Tayyaba, Bibi Yamin, El Askary Ahmad, Gharib Amal F., Elmissbah Tariq E., Elesawy Basem H., and Qayyum Abdul
- Subjects
chittra ,diseases ,ethnomedicine ,kalri ,medicinal plants ,pandi ,topi ,Chemistry ,QD1-999 - Abstract
An ethnomedicinal expedition was conducted to collect and record indigenous knowledge about the use of medicinal plants by local inhabitants of four villages (Chittra, Topi, Pandi, and Kalri) of district Bagh, Azad Jammu and Kashmir. Ethnomedicinal data were obtained from 60 randomly selected local inhabitants of the study area through semi-structured questionnaires and interviews. These data were analyzed quantitatively through different ethnobotanical indices including family importance value, relative frequency of citation, use value (UV), fidelity level (FL), informant consensus factor (ICF), and Jaccard index (JI). our study reported 69 medicinal plants belonging to 39 families. Rosaceae (9 species) was a dominant family of the study area. Herb (54.83%) was dominant growth form of plants used for medicinal purpose. Leaves contributed maximum usage (44.29%) for curing diseases. Decoction (23 records) was most used mode of utilization. Relative frequency of citation and UV ranged from 0.03–0.85 and 0.05–1.17, respectively. There were 4 plant species with 100% FL. Highest ICF (0.88%) was found for gastrointestinal diseases. By comparing results with previous study, JI ranged from 0.54 to 24.43%. Our results found that there were 18 plant species not reported with ethnomedicinal aspect in previous studies from district Bagh region. The research of this study concludes that the area is rich with medicinal plants and the local inhabitant of this area still prefer medicinal plants over allopathic medicines for treating different ailments. Comparative analysis has shown some novel uses of plant species which may be due to cultural differences of the study area. However, awareness and pharmacological study are needed to conserve and unveil pharmaceutically important plants.
- Published
- 2022
- Full Text
- View/download PDF
14. Analysis of business behavior and HRM perspectives on post-COVID-19 SME business sustainability
- Author
-
Nuraini Asriati, S. Syamsuri, Munawar Thoharudin, Sandra Fitria Wardani, and Aditya Halim Perdana Kusuma Putra
- Subjects
Human resources management ,business strategy ,business sustainability ,planned behavior theory ,SME ,J24 ,Business ,HF5001-6182 ,Management. Industrial management ,HD28-70 - Abstract
There are not many studies that examine business continuity and business strategy combined with business people’s psychological and psychological approaches. This study relates the elaboration between the HRM, strategic management, and business management fields analyzed with a quantitative approach. This study involved 100 respondents of handicraft business actors at the border between Indonesia and Malaysia. The data collection method used a survey method. Data processing uses the Structural Equation Model (SEM-PLS) approach in the SMART-PLS. This research study states that through direct relationship, all demonstration variables have a positive and significant effect. Meanwhile, the demonstration of the relationship between variables states that there are two patterns of relationship that do not have a significant effect. Through a combination of human resource management variables, business strategy, creativity, entrepreneurship capability, and SME sustainability perceived, packaged with a planned behavior theory (TPB) approach, several main research findings conclude. First, our study indicate that business sustainability can be achieved if an optimal business strategy (BS) has been realized by forming good entrepreneurial capabilities. Second, the role of antecedent human resource locus of control (HR) is a variable that has complete control in creating the creativity of small-medium enterprise actors and creating entrepreneurial capabilities.
- Published
- 2022
- Full Text
- View/download PDF
15. Pendidikan Literasi Keuangan Dalam Pembelajaran Ekonomi di SMA dan SMK Kabupaten Kubu Raya Kalimantan Barat
- Author
-
Maria Ulfah, Heni Kuswanti, and Munawar Thoharudin
- Subjects
financial literation education ,economic learning. ,Education - Abstract
The purpose of this study was to analyze financial literacy education in the Economic Learning of SMA and SMK in Kubu Raya Regency, West Kalimantan. The method used in this research was descriptive method with survey research form. This research was conducted at SMA and SMK in Kubu Raya Regency, West Kalimantan. The subjects of this study were teachers of economics subjects and principals or vice principal for curriculum of SMA and SMK in Kubu Raya Regency. The data collection technique used interview sheets and direct observation, while data analysis technique used descriptive analysis. Based on the results of research, it was found that 1) The material on defining economic transactions and various types of practice, introduction to economic resources, introduction to the concept of shopping. ) as a fulfillment of basic needs, introduction to the concept of saving in traditional and modern terminology, introduction to the concept of sharing (sharing) found in economic learning; 2) While the introduction to the concept of bad practices and financial crimes is not included in the syllabus of economic subjects, some teachers on their own initiative provide additional material on corruption to the students.
- Published
- 2021
- Full Text
- View/download PDF
16. Edu-Finance Management Model in BOS Fund Management to Create Financial Well-Being
- Author
-
Maria Ulfah and Munawar Thoharudin
- Subjects
edu-finance management model ,financial wellbeing ,fund management ,Education (General) ,L7-991 - Abstract
The purpose of this study is to analyze the implementation of BOS fund management and to design an edu-finance management model in order to achieve school financial well-being. The research approach used was a qualitative approach. Data sources consisted of BOS fund managers and school principals. Data collection techniques included FGDs with BOS fund managers; interview; and documentation. Data analysis techniques used the Miles and Hubermans model including data reduction, data presentation and drawing conclusions and verification. The conclusion of this research is that the compilers of school financial planning and work programs are made only to fulfill administrative requirements; the implementation of financial management in the management of BOS fund is still low; in making accountability reports, many do not understand the evidence documents that must be prepared and financial management training has not been carried out in accordance with the needs. After being given edu-finance training, the BOS fund managers understand the preparation of work programs, the use of BOS fund based on a priority scale, and the preparation of accountability reports along with the files that should be prepared.
- Published
- 2020
- Full Text
- View/download PDF
17. The Harapan Jaya Cooperative Development Reviewed from the Cooperative Financial Capital and Business
- Author
-
Munawar Thoharudin, Fatkhan Amirul Huda, and Tedi Suryadi
- Subjects
cooperatives ,capital ,cooperative businesses ,Theory and practice of education ,LB5-3640 - Abstract
The purpose of this study was to find out how the Harapan Jaya Cooperative development in terms of cooperative financial capital and business. In financial capital, there are assets, incomes, and Net Income. While the business is from the business run by the cooperative. This study uses a qualitative descriptive method. In this study, the researcher acts as a data collector and as an active instrument to collect data. This research uses two data sources; they are primary and secondary data. Data collection was conducted by researchers using in-depth interviews, documentation and observation. Data analyzed using qualitative analysis, the validity of the data using the triangulation method. The Harapan Jaya Cooperative Capital development in this study was reviewed from the Solvency, Liquidity and Profitability Ratio. Overall shows good and excellent criteria. The development of the cooperative business is indicated by the addition of income from savings and loan units, management of plasma tubers, dump truck rental, beko heavy equipment rental, motor grader heavy equipment. In addition, business development is also seen from the addition of dump trucks and heavy equipment owned by cooperatives.
- Published
- 2020
- Full Text
- View/download PDF
18. Surface modification of silicananoparticles for immobilize probe DNA to identify aspergillus flavus
- Author
-
Aruna, Kasoju, primary and Mohammad Munawar, T., additional
- Published
- 2013
- Full Text
- View/download PDF
19. A study on the probabilities of the production of biodiesel from naturally isolated bacterial sources.
- Author
-
Gangadhara, R., Mohammad Munawar, T., Diwakar Reddy, K., Prasad, N. B. L., and Jayasimha Rayalu, D.
- Subjects
- *
BIODIESEL fuels , *VEGETABLE oils , *METHYL ether , *GLYCERIN , *HYDROCARBONS - Abstract
Technically, biodiesel is vegetable oil methyl ester. It is formed by removing triglyceride molecule from vegetable oil in the form of glycerin (soap). Once the glycerin is removed from the oil, the remaining molecules are, to a diesel engine, similar to petroleum diesel fuel. There are some notable differences. The biodiesel molecules are very simple hydrocarbon chains, containing no sulfur, ring molecules or aromatics associated with fossil fuels. For about 30 years the thirst to find independence from these fossil fuels has driven man kind to those alternatives which not only give assurity in the quality of the fuel but also its renewability. These efforts have given the origin of biodiesel from plants and algal origin. Due to various industrial and commercial problems in these productions a new alternative source for biodiesel has taken the lime light. Bacterial based biodiesel production has taken new shape in this decade; especially the industrial importance of bacteria fermentations has assured that this source can bring big positive shift in the biodiesel market in the coming years. In this project main strategy is laid around isolating and analyzing various selected bacterial strains for their abilities to produce Fatty acid based biomolecules and also concentrates on the optimization of the nutrient medium to maximize lipid output for biodiesel production. [ABSTRACT FROM AUTHOR]
- Published
- 2013
20. Boosted charge separation via Ce 2 S 3 over dual Z-scheme ZnO-Ce 2 S 3 -MnO 2 core double-shell nanocomposite for the degradation of diverse dye pollutants.
- Author
-
Munawar T, Alomar TS, Yan CF, Fatima S, Mukhtar F, Nadeem MS, AlMasoud N, Khan SA, Koc M, Zakaria Y, and Iqbal F
- Subjects
- Oxides chemistry, Sulfides chemistry, Catalysis, Nanocomposites chemistry, Zinc Oxide chemistry, Coloring Agents chemistry, Manganese Compounds chemistry, Water Pollutants, Chemical chemistry, Cerium chemistry
- Abstract
Herein, core double-shell direct dual Z-scheme ZnO-Ce
2 S3 -MnO2 nanocomposite was synthesized via a hydrothermal route along with pure ZnO, Ce2 S3 , MnO2 , and characterized by numerous characterization tools for application in synthetic dyes degradation. The XRD, Raman, and FTIR analyses have confirmed the nanocomposite formation. TEM images exhibited the core double-shell morphology with an average particle diameter of 81 nm and stacking of ZnO, Ce2 S3 , and MnO2 . EDX confirmed the existence of desired elements in the grown composition. The varied oxidation states, presence of defects, and fast charge transfer were also revealed from XPS, PL, and EIS. The ZnO-Ce2 S3 -MnO2 nanocomposite has an optical energy bandgap of 2.84 eV, capable of decomposing harmful dyes with excellent efficiency, 99.81% MB, 97.62% MO, 88.5% MR, and 58.9% EY in 40 min sunlight exposure. The effect of several operating parameters is also observed and obtained results showed the optimal catalyst dose was 20 mg, pH of 8, and dye concentration of 10 ppm. The scavenger's experiment suggests that• O2 - and• OH are the main active radicals in the photodegradation reaction which is also evident in the dual Z-scheme formation. The MnO2 and ZnO layers covered the Ce2 S3 (core) and dual Z-scheme formation allows rapid kinetics of redox reaction and provides plenteous channels for transfer of photo-generated charge carriers during photocatalysis. Thus, core double-shell direct dual Z-scheme photocatalysts having inorganic components could be an excellent choice for photocatalysis at the industrial level, particularly for water purification., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Inc. All rights reserved.)- Published
- 2024
- Full Text
- View/download PDF
21. Liver Hemorrhage Following Mechanical CPR With the Lund University Cardiopulmonary Assist System (LUCAS) Device: A Focused Case Report.
- Author
-
Harb H, Munawar T, Al-Obaidi H, Shehzad Z, and Sonnino A
- Abstract
Cardiac arrest is a leading cause of mortality globally, and mechanical CPR devices like the LUCAS system are designed to improve outcomes by enhancing consistency and reducing rescuer fatigue. However, this case report of a 76-year-old female who suffered cardiac arrest post-flight reveals significant complications associated with mechanical CPR. Despite achieving initial resuscitation, she developed extensive liver damage and additional complications, which ultimately led to her death. This case underscores the importance of precise training and strict adherence to guidelines when using mechanical CPR devices. It highlights that while these devices offer potential benefits, they also pose risks, especially for vulnerable patients, necessitating careful consideration and ongoing evaluation to optimize safety and effectiveness., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Harb et al.)
- Published
- 2024
- Full Text
- View/download PDF
22. Electrolysis products, reactive oxygen species and ATP loss contribute to cell death following irreversible electroporation with microsecond-long pulsed electric fields.
- Author
-
Rajagopalan NR, Munawar T, Sheehan MC, Fujimori M, Vista WR, Wimmer T, Gutta NB, Solomon SB, and Srimathveeravalli G
- Subjects
- Swine, Animals, Reactive Oxygen Species, Cell Death, Adenosine Triphosphate, Electroporation methods, Electrolysis
- Abstract
Membrane permeabilization and thermal injury are the major cause of cell death during irreversible electroporation (IRE) performed using high electric field strength (EFS) and small number of pulses. In this study, we explored cell death under conditions of reduced EFS and prolonged pulse application, identifying the contributions of electrolysis, reactive oxygen species (ROS) and ATP loss. We performed ablations with conventional high-voltage low pulse (HV-LP) and low-voltage high pulse (LV-HP) conditions in a 3D tumor mimic, finding equivalent ablation volumes when using 2000 V/cm 90 pulses or 1000 V/cm 900 pulses respectively. These results were confirmed by performing ablations in swine liver. In LV-HP treatment, ablation volume was found to increase proportionally with pulse numbers, without the substantial temperature increase seen with HV-LP parameters. Peri-electrode pH changes, ATP loss and ROS production were seen in both conditions, but LV-HP treatments were more sensitive to blocking of these forms of cell injury. Increases in current drawn during HV-LP was not observed during LV-HP condition where the total ablation volume correlated to the charge delivered into the tissue which was greater than HV-LP treatment. LV-HP treatment provides a new paradigm in using pulsed electric fields for tissue ablation with clinically relevant volumes., Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Govindarajan Srimathveeravalli reports financial support was provided by National Institutes of Health. Govindarajan Srimathveeravalli reports financial support was provided by Congressionally Directed Medical Research Program. Govindarajan Srimathveeravalli reports a relationship with Aperture Medical that includes: equity or stocks., (Copyright © 2023 Elsevier B.V. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
23. Novel enrichment in biobased monomers of waterborne polyurethane dispersions as a textile finishing agent for poly-cotton fabrics.
- Author
-
Rashid KT, Akram N, Zia KM, Usman M, and Munawar T
- Subjects
- Textiles, Coloring Agents, Polymerization, Cotton Fiber, Polyurethanes
- Abstract
This study introduces a novel biobased textile finishing agent synthesized as waterborne polyurethane dispersions (FCCB-WPUDs), utilizing bio-based monomers like fenugreek oil-based polyol, corn oil-derived emulsifier, and cellulose acetate butyrate (CAB) chain extender. The FCCB-WPUDs were prepared through the prepolymer polymerization method and characterized using FTIR, TGA, DMA, SEM, DLS, and swelling tests. Their application to poly-cotton fabrics significantly improved various fabric properties. The enhancements included increased washing fastness (from 3/4 ± 0.01 to 4 ± 0.02 for dyed and 3 ± 0.02 to 4/5 ± 0.02 for printed fabrics), rubbing fastness (from 3 ± 0.02 to 4/5 ± 0.03 for dyed and 4 ± 0.02 to 4/5 ± 0.03 for printed fabrics), and perspiration fastness (from 3 ± 0.02 to 4 ± 0.03 for acidic dyed and 3/4 ± 0.02 to 4 ± 0.02 for alkaline printed fabrics). Additionally, tear strengths improved significantly (from 13.66 ± 0.04 N/m to 20.53 ± 0.06 N/m for warp dyed and 10.85 ± 0.06 N/m to 15.14 ± 0.06 N/m for warp printed fabrics), along with tensile strengths (from 327 ± 5.38 N/m to 361 ± 3.26 N/m for warp dyed and 357 ± 5.34 N/m to 449 ± 4.90 N/m for warp printed fabrics). These improvements correlated with increasing CAB moles as a chain extender. This research presents a cost-effective and simple biobased method for textile finishing, offering an alternative to petrochemical-based monomers in conventional WPUD preparation., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier B.V. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
24. Synergistic effect of a bamboo-like Bi 2 S 3 covered Sm 2 O 3 nanocomposite (Bi 2 S 3 -Sm 2 O 3 ) for enhanced alkaline OER.
- Author
-
Munawar T, Fatima S, Batoo KM, Bashir A, Mukhtar F, Hussain S, Manzoor S, Ashiq MN, Khan SA, Koc M, and Iqbal F
- Abstract
The availability of hydrogen energy from water splitting through the electrocatalytic route is strongly dependent on the efficiency, durability, and cost of the electrocatalysts. Herein, a novel Bi
2 S3 -covered Sm2 O3 (Bi2 S3 -Sm2 O3 ) nanocomposite electrocatalyst was developed by a hydrothermal route for the oxygen evolution reaction (OER). The electrochemical properties were studied in 1.00 mol KOH solution after coating the target material on the stainless-steel substrate (SS). Physical analysis via XRD, FTIR, IV, TEM/EDX, and XPS revealed that the Bi2 S3 -Sm2 O3 composite possesses metallic surface states, thereby displaying unconventional electron dynamics and purity of phases. The Bi2 S3 -Sm2 O3 composite shows outstanding OER activity with a low overpotential of 197 mV and a Tafel slope of 74 mV dec-1 at a 10 mA cm-2 current density as compared to pure Bi2 S3 and Sm2 O3 . Meanwhile, the composite catalyst retains high stability even after 100 h of the chronoamperometry test. Thus, this work unveils a new avenue for the speedy flow of electrons, which is attributed to the synergetic effect between Bi2 S3 and Sm2 O3 , as well as enriched interfacial defects, which exhibit greater oxygen adsorption capability with improved electronic assemblies in the active interfacial region. In addition, the introduced porous structure in core-shell Bi2 S3 -Sm2 O3 provides extraordinary electrical properties. Thus, this article offers a realistic framework for electrochemical energy generation.- Published
- 2024
- Full Text
- View/download PDF
25. Practices of Informed Consent for Emergency Procedures at a Tertiary Care Hospital in Lahore, Pakistan.
- Author
-
Munawar T, Ismail F, Mehmood Qadri H, Haq AU, Munawar A, Zahid AS, Sheraz M, and Babar MS
- Abstract
Background The purpose of obtaining informed consent is to ensure that patients undergoing any medical or surgical intervention are neither deceived nor coerced. Accurately estimating surgical risks is critical for shared decision-making and informed consent. Probable complications and alternative procedures should be presented to the patient so that they can freely choose an operative option. However, this factor is difficult to carry on in emergencies where an urgent decision is required. Objective This study aimed to assess the ongoing clinical practices of informed consent in emergency surgeries at a tertiary care facility. Materials and methods A cross-sectional survey was carried out from March 2022 to June 2022 at the Department of General Surgery, Lahore General Hospital, Lahore, Pakistan, with patients who had undergone surgical procedures under local, spinal, or general anesthesia within 24 hours of presentation. A Google Form (Google Inc., Mountainview, CA) was designed, containing a predefined set of 32 standard questions, and patients were interviewed in their native language to assess their satisfaction regarding the pattern and components of emergency informed consent. Categorical data were assessed using measures of central tendency, frequencies, and percentages. Results A total of 169 patients were selected for the study. Only 1.6% of them signed the consent form themselves, while 93.5% of the forms were signed by their first-degree relatives. Verbal consent was taken in 4.8% of cases. In 88% of cases, informed consent was obtained by the house surgeons. The majority of patients, i.e., 78.2%, were not able to read the written consent form; however, 83.1% understood the verbal information. About 66.3% of patients agreed that they were informed about the nature of their disease, while 67.5%, 14.8%, and 13.7% affirmed that they were explained the nature of surgical intervention, associated risks, and type of anesthesia, respectively. Overall, 59.5% of patients felt satisfied with the process of informed consent. About 91.1% of the patients believed that their decisions were unaffected by the procurement of informed consent. Conclusion The existing practices of informed consent and comprehension by the population were found to be substandard. Physicians seem to ignore bioethics, and patients appear to be unaware of their basic rights. Although practiced at our center, not all components of informed consent were communicated to the patients. The risks of the procedures and the mode of anesthesia used were not well addressed by doctors. There is a grave need to educate the medical community about the legal and ethical aspects of informed consent, as well as the public masses regarding their rights., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Munawar et al.)
- Published
- 2023
- Full Text
- View/download PDF
26. Fabrication of fullerene-supported La 2 O 3 -C 60 nanocomposites: dual-functional materials for photocatalysis and supercapacitor electrodes.
- Author
-
Munawar T, Sardar S, Mukhtar F, Nadeem MS, Manzoor S, Ashiq MN, Khan SA, Koc M, and Iqbal F
- Abstract
Nowadays, water pollution and energy crises worldwide force researchers to develop multi-functional and highly efficient nanomaterials. In this scenario, the present work reports a dual-functional La
2 O3 -C60 nanocomposite fabricated by a simple solution method. The grown nanomaterial worked as an efficient photocatalyst and proficient electrode material for supercapacitors. The physical and electrochemical properties were studied by state-of-the-art techniques. XRD, Raman spectroscopy, and FTIR spectroscopy confirmed the formation of the La2 O3 -C60 nanocomposite with TEM nano-graphs, and EDX mapping exhibits the loading of C60 on La2 O3 particles. XPS confirmed the presence of varying oxidation states of La3+ /La2+ . The electrochemical capacitive properties were tested by CV, EIS, GCD, ECSA, and LSV, which indicated that the La2 O3 -C60 nanocomposite can be effectively used as an electrode material for durable and efficient supercapacitors. The photocatalytic test using methylene blue (MB) dye revealed the complete photodegradation of the MB dye under UV light irradiation after 30 min by a La2 O3 -C60 catalyst with a reusability up to 7 cycles. The lower energy bandgap, presence of deep-level emissions, and lower recombination rate of photoinduced charge carriers in the La2 O3 -C60 nanocomposite than those of bare La2 O3 are responsible for enhanced photocatalytic activity with low-power UV irradiation. The fabrication of multi-functional and highly efficient electrode materials and photocatalysts such as La2 O3 -C60 nanocomposites is beneficial for the energy industry and environmental remediation applications.- Published
- 2023
- Full Text
- View/download PDF
27. Physiological, Psychosocial and Substance Abuse Effects of Pornography Addiction: A Narrative Review.
- Author
-
Mehmood Qadri H, Waheed A, Munawar A, Saeed H, Abdullah S, Munawar T, Luqman S, Saffi J, Ahmad A, and Babar MS
- Abstract
Internet pornography provides explicit content in various forms and can progress from habit to addiction. The consumption of online porn has risen due to the general use of current technology. The main reasons people consume it are sexual arousal and sexual enhancement. We planned this review study to identify the reasons for online pornography utilization, the mechanisms involved in its addiction, and its physiological, emotional, behavioral, social, and substance abuse effects. After a detailed literature search using PubMed Central and Google Scholar, four case studies and nine original articles from 2000 to 2022 were included. The main findings of the literature demonstrated that watching porn was most frequently done out of boredom, for sexual gratification, and to pick up new fashion and behavior ideas from these movies. In all facets of the users' lives, negative consequences were seen. Due to the explosion of new technologies, online pornography has risen to an alarming level, which has very injurious effects on societies and individuals. Therefore, it is high time to get rid of this addiction to protect our lives from its harmful effects., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Mehmood Qadri et al.)
- Published
- 2023
- Full Text
- View/download PDF
28. Dual Z-scheme core-shell PANI-CeO 2 -Fe 2 O 3 -NiO heterostructured nanocomposite for dyes remediation under sunlight and bacterial disinfection.
- Author
-
Mukhtar F, Munawar T, Nadeem MS, Naveed Ur Rehman M, Khan SA, Koc M, Batool S, Hasan M, and Iqbal F
- Subjects
- Bacteria, Bromides, Cetrimonium, Coloring Agents, Disinfection, Escherichia coli, Oxides chemistry, Staphylococcus aureus, Sunlight, Surface-Active Agents, Water, Environmental Pollutants, Nanocomposites chemistry
- Abstract
Nowadays, environmental pollution due to discharge of organic pollutants from food, textile, and pharmaceutical industries into clean water and development of contagious diseases due to pathogenic organisms provide impetus to material researcher to fabricate novel design for efficient photocatalyst and antimicrobial agents. In this regard, designing a core-shell heterojunction catalyst based on metal oxides is considered an auspicious approach. In present study, combating the problems of singular oxides, core-shell PANI-CeO
2 -Fe2 O3 -NiO nanocomposite (PCFN) and CeO2 -Fe2 O3 -NiO nanocomposite (CFN) was synthesized through sol-gel and oxidative polymerization route with cetyletrimethylammonium bromide (CTAB) as surfactant. The XRD, FTIR, and Raman confirmed the formation of nanocomposites with core-shell morphology composed of PANI (shell) and oxides (Core) in PCFN with a particle size of 52 nm (TEM). Surprisingly, PCFN has lower band gap, e- /h+ recombination, and larger charge transfer character than CFN. The decomposition test using MB and MO dyes showed that PCFN degraded 99%, 98%, while CFN degraded only 73% and 54%, respectively, under 50 min sunlight illumination. The reusability was assessed up to 7th cycle for PCFN. The influence of operational parameters (catalyst dose, dye concentration, pH) was tested for PCFN. Further, the antimicrobial action against S. aureus (gram + ve), E. coli (gram -ve) were also tested. The supreme performance of PCFN has been credited to heterostructure dual Z-scheme formation and core-shell morphology supported with PANI, which suppresses the e- /h+ recombination process by promoting their separation. The present finding indicated that the PCFN is a promising modifier for bacterial disinfection and acts as a superb photocatalyst through core-shell formation with PANI support., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 Elsevier Inc. All rights reserved.)- Published
- 2022
- Full Text
- View/download PDF
29. Transition metal-doped SnO 2 and graphene oxide (GO) supported nanocomposites as efficient photocatalysts and antibacterial agents.
- Author
-
Munawar T, Nadeem MS, Mukhtar F, Rehman MNU, Riaz M, Batool S, Hasan M, and Iqbal F
- Subjects
- Oxygen, Anti-Bacterial Agents pharmacology, Staphylococcus aureus
- Abstract
In the present work, pristine and transition metal (TM) (W, Ag, Zn)-doped SnO
2 nanocrystals using a facile sol-gel approach were synthesized. The grown products were anchored on graphene oxide (GO) sheets via a simple ultrasonication technique to fabricate binary nanocomposites. The structural, optical, and morphological properties of as-synthesized samples were studied by XRD, FTIR, Raman, EDX, UV-Visible, PL, and FE-SEM. The charge transferability of graphene oxide-based samples was investigated by EIS. The XRD exhibited the TM doping in SnO2 and the development of GO-based nanocomposite. FTIR data evidenced the existence of the metal-oxygen bonds. Raman spectra presented the optical phonon modes of SnO2 and the existence of oxygen vacancy defects. FE-SEM images demonstrated the anchoring of particles on the GO sheet, and EDX further approved the existence of desired dopants. The integration of SnO2 with TM doping remarkably reduced optical bandgap (3.65-3.10 eV), which was further decreased (3.10-2.99 eV) by making composite with GO. The photodegradation results exhibited that GO-based nanocomposites have the higher potential to degrade synthetic dyes (methyl red (MR), and methyl orange (MO) and SnZnO2 /GO have shown superb photocatalytic performance after 80-min sunlight illumination (99.9% MR and 95.0% MO dyes) with the higher rate constant and superior stability up to 6th cycle against MR dye. The grown samples were tested for bacterial disinfection, and SnZnO2 /GO sample showed a higher zone of inhibition towards S. aureus and K. pneumoniae bacteria strains. The greater charge transfer rate and lower recombination of charge carriers in GO-based composites were also observed by EIS and PL analysis. Moreover, the present article ascribed that the photocatalytic and antibacterial properties of bare SnO2 could be improved by TM doping and fabricating their composite with GO., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)- Published
- 2022
- Full Text
- View/download PDF
30. Fabrication of Cr-ZnFe 2 O 4 /S-g-C 3 N 4 Heterojunction Enriched Charge Separation for Sunlight Responsive Photocatalytic Performance and Antibacterial Study.
- Author
-
Zhang P, Munawar T, Soltane R, Javed M, Liu G, Iqbal S, Qamar MA, Dera AA, Alrbyawi H, Alfakeer M, Rabea S, and Elkaeed EB
- Subjects
- Catalysis, Gram-Negative Bacteria, Gram-Positive Bacteria, Surface-Active Agents, Water, Anti-Bacterial Agents pharmacology, Sunlight
- Abstract
There has been a lot of interest in the manufacture of stable, high-efficiency photocatalysts. In this study, initially Cr doped ZnFe
2 O4 nanoparticles (NPs) were made via surfactant-assisted hydrothermal technique. Then Cr-ZnFe2 O4 NPs were modified by incorporating S-g-C3 N4 to enhance their photocatalytic efficiency. The morphological, structural, and bonding aspects were analyzed by XRD, FTIR, and SEM techniques. The photocatalytic efficiency of the functional Cr-ZnFe2 O4 /S-g-C3 N4 (ZFG) heterostructure photocatalysts was examined against MB under sunlight. The produced ZFG-50 composite has the best photocatalytic performance, which is 2.4 and 3.5 times better than that of ZnFe2 O4 and S-g-C3 N4 , respectively. Experiments revealed that the enhanced photocatalytic activity of the ZFG nanocomposite was caused by a more effective transfer and separation of photo-induced charges. The ZFG photocatalyst can use sunlight for treating polluted water, and the proposed modification of ZnFe2 O4 using Cr and S-g-C3 N4 is efficient, affordable, and environmentally benign. Under visible light, Gram-positive and Gram-negative bacteria were employed to ZFG-50 NCs' antimicrobial activity. These ZFG-50 NCs also exhibit excellent antibacterial potential.- Published
- 2022
- Full Text
- View/download PDF
31. Energy-levels well-matched direct Z-scheme ZnNiNdO/CdS heterojunction for elimination of diverse pollutants from wastewater and microbial disinfection.
- Author
-
Nadeem MS, Munawar T, Mukhtar F, Batool S, Hasan M, Akbar UA, Hakeem AS, and Iqbal F
- Subjects
- Anti-Bacterial Agents pharmacology, Coloring Agents pharmacology, Disinfection, Escherichia coli, Methylene Blue, Wastewater, Environmental Pollutants pharmacology, Zinc Oxide pharmacology
- Abstract
Energy-levels well-matched direct Z-scheme ZnNiNdO/CdS heterojunction was successfully fabricated using facile co-precipitation and ultra-sonication techniques and characterized with XRD, FTIR, Raman, PL, UV-vis, and FE-SEM. The XRD diffractograms confirmed the co-doping of Ni-Nd in ZnO and the formation of heterostructured nanocomposite. FTIR and Raman data showed the presence of metal-oxygen vibration and optical phonon modes of ZnO and CdS. FE-SEM images exhibited the network type morphology. The energy bandgap was redshifted by co-doping (3.37-2.9 eV) and was further reduced (2.6 eV) by making a composite with CdS. The ZnNiNdO/CdS catalyst degraded 99.7, 49, 96.6, 98.6, and 98.6% methylene blue (MB), p-nitroaniline (P-Nitro), methyl orange (MO), methyl red (MR), and rhodamine B (RhB) dyes under 50 min sunlight irradiation. Moreover, ZnNiNdO/CdS showed intense inhibition activity towards Staphylococcus aureus, Escherichia coli, Proteus vulgaris, and Pseudomonas aeruginosa bacterial strains with maximum inhibition zone diameters 30, 33, 27, and 31 mm, respectively. The synergistic effects arising from band alignment can lead to efficient vectorial charge separation, transportation, and lower recombination of photoinduced charge carriers, ultimately boosting photocatalytic and antibacterial performance. The ZnNiNdO/CdS photocatalyst has higher stability up to the 7th cycle towards MB dye with ~ 5% deficit in degradation efficiency. The higher generation of superoxide and hydroxyl radical was confirmed by species trapping experiments responsible for photodegradation of dyes molecules. Furthermore, the results showed that the photocatalytic and antibacterial performance of pristine ZnO can be enhanced by co-doping and tuning energy bandgap., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
- Full Text
- View/download PDF
32. Sunlight-induced photocatalytic degradation of various dyes and bacterial inactivation using CuO-MgO-ZnO nanocomposite.
- Author
-
Munawar T, Mukhtar F, Yasmeen S, Naveed-Ur-Rehman M, Nadeem MS, Riaz M, Mansoor M, and Iqbal F
- Subjects
- Bacteria, Catalysis, Coloring Agents, Copper, Magnesium Oxide, Sunlight, Nanocomposites, Zinc Oxide
- Abstract
Novel tri-phase CuO-MgO-ZnO nanocomposite was prepared using the co-precipitation technique and investigated its physical properties using characterization techniques including XRD, FTIR, Raman, IV, UV-vis, PL, and SEM. The application of grown CuO-MgO-ZnO nanocomposite for the degradation of various dyes under sunlight and antibacterial activity against different bacteria were studied. The XRD confirmed the existence of diffraction peaks related to CuO (monoclinic), MgO (cubic), and ZnO (hexagonal) with CuO phase 40%, MgO 24%, and ZnO 36%. The optical energy gap of nanocomposite was 2.9 eV, which made it an efficient catalyst under sunlight. Raman and FTIR spectra have further confirmed the formation of the nanocomposite. SEM images revealed agglomerated rod-shaped morphology. EDX results showed the atomic percentage of a constituent element in this order Cu>Zn>Mg. PL results demonstrate the presence of intrinsic defects. The photocatalytic activity against methylene blue (MB), methyl orange (MO), rhodamine-B (RhB), cresol red (CR), and P-nitroaniline (P-Nitro) dyes has shown the excellent degradation efficiencies 88.5%, 93.5%, 75.9%, 98.8%, and 98.6% at 5 ppm dye concentration and 82.6%, 83.6%, 64.3%, 93.1%, and 94.3% at 10 ppm dye concentration in 100 min, respectively, under sunlight illumination. The higher degradation is due to the generation of superoxide and hydroxyl radicals. The recyclability test showed the reusability of catalyst up to the 5th cycle. The antibacterial activity against Escherichia coli, Klebsiella pneumoniae, Proteus Vulgaris, Staphylococcus aureus, and Pseudomonas aeruginosa bacteria with the zone of inhibition 30, 31, 30, 30, and 30 mm, respectively, was achieved., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2021
- Full Text
- View/download PDF
33. Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.
- Author
-
Ketas TJ, Chaturbhuj D, Portillo VMC, Francomano E, Golden E, Chandrasekhar S, Debnath G, Díaz-Tapia R, Yasmeen A, Kramer KD, Munawar T, Leconet W, Zhao Z, Brouwer PJM, Cushing MM, Sanders RW, Cupo A, Klasse PJ, Formenti SC, and Moore JP
- Abstract
The approved Pfizer and Moderna mRNA vaccines are well known to induce serum antibody responses to the SARS-CoV-2 Spike (S)-protein. However, their abilities to elicit mucosal immune responses have not been reported. Saliva antibodies represent mucosal responses that may be relevant to how mRNA vaccines prevent oral and nasal SARS-CoV-2 transmission. Here, we describe the outcome of a cross-sectional study on a healthcare worker cohort (WELCOME-NYPH), in which we assessed whether IgM, IgG, and IgA antibodies to the S-protein and its receptor-binding domain (RBD) were present in serum and saliva samples. Anti-S-protein IgG was detected in 14/31 and 66/66 of saliva samples from uninfected participants after vaccine doses-1 and -2, respectively. IgA antibodies to the S-protein were present in 40/66 saliva samples after dose 2. Anti-S-protein IgG was present in every serum sample from recipients of 2 vaccine doses. Vaccine-induced antibodies against the RBD were also frequently present in saliva and sera. These findings may help our understanding of whether and how vaccines may impede SARS-CoV-2 transmission, including to oral cavity target cells., Competing Interests: None of the authors declares a competing interest., (Copyright © Pathogens and Immunity 2021.)
- Published
- 2021
- Full Text
- View/download PDF
34. Bioinspired synthesis of zinc oxide nano-flowers: A surface enhanced antibacterial and harvesting efficiency.
- Author
-
Hasan M, Altaf M, Zafar A, Hassan SG, Ali Z, Mustafa G, Munawar T, Saif MS, Tariq T, Iqbal F, Khan MW, Mahmood A, Mahmood N, and Shu X
- Subjects
- Anti-Bacterial Agents pharmacology, Microbial Sensitivity Tests, Pseudomonas aeruginosa, Staphylococcus aureus, Zinc Oxide pharmacology
- Abstract
Despite of broad range application, the cost effective, highly stable and reproduceable synthesis of ZnO is needed, especially which can make it biosafe as well. Here, a unique bioinspired synthesis of ZnO nanoflowers (NFs) has been introduced using Withania coagulans extract as reducing agent. Different molar concentrations were assessed to counter the effect of structural, morphological, antibacterial activity and high efficiency of algae harvesting. The UV-spectroscopy authenticates the synthesis of ZnO NFs having Wurtzite hexagonal structure with the size in the range of 360-550 nm. While surface analysis revealed the presence of stabilizing agent like phenolic, amine, etc. on surface of ZnO NFs. These perineum ZnO NFs exhibited a stronger antibacterial with Gram-positive bacteria Staphylococcus aureus as compare to Gram-negative bacteria Pseudomonas aeruginosa and greater harvesting efficiency up to 94% on the account of greater surface area and unique surface chemistry, thus leading a new horizon of more efficient and effective applications for ethanol production., (Copyright © 2020. Published by Elsevier B.V.)
- Published
- 2021
- Full Text
- View/download PDF
35. Fractionation of Biomolecules in Withania coagulans Extract for Bioreductive Nanoparticle Synthesis, Antifungal and Biofilm Activity.
- Author
-
Hasan M, Zafar A, Shahzadi I, Luo F, Hassan SG, Tariq T, Zehra S, Munawar T, Iqbal F, and Shu X
- Subjects
- Aspergillus niger drug effects, Candida albicans drug effects, Chemical Fractionation methods, Hexanes chemistry, Methanol chemistry, Microbial Sensitivity Tests, Pseudomonas aeruginosa drug effects, Solvents chemistry, Staphylococcus aureus drug effects, Anti-Bacterial Agents pharmacology, Antifungal Agents pharmacology, Biofilms drug effects, Cobalt chemistry, Metal Nanoparticles chemistry, Oxides chemistry, Phytochemicals pharmacology, Plant Extracts pharmacology, Withania chemistry
- Abstract
Withania coagulans contains a complex mixture of various bioactive compounds. In order to reduce the complexity of the plant extract to purify its phytochemical biomolecules, a novel fractionation strategy using different solvent combination ratios was applied to isolate twelve bioactive fractions. These fractions were tested for activity in the biogenic synthesis of cobalt oxide nanoparticles, biofilm and antifungal activities. The results revealed that plant extract with bioactive fractions in 30% ratio for all solvent combinations showed more potent bioreducing power, according to the observed color changes and the appearance of representative absorption peaks at 500-510 nm in the UV-visible spectra which confirm the synthesis of cobalt oxide nanoparticles (Co
3 O4 NPs). XRD diffraction was used to define the crystal structure, size and phase composition of the products. The fractions obtained using 90% methanol/hexane and 30% methanol/hexane showed more effectiveness against biofilm formation by Pseudomonas aeruginosa and Staphylococcus aureus so these fractions could potentially be used to treat bacterial infections. The 90% hexane/H2 O fraction showed excellent antifungal activity against Aspergillus niger and Candida albicans , while the 70% methanol/hexane fraction showed good antifungal activity for C. albicans , so these fractions are potentially useful for the treatment of various fungal infections. On the whole it was concluded that fractionation based on effective combinations of methanol/hexane was useful to investigate and study bioactive compounds, and the active compounds from these fractions may be further purified and tested in various clinical trials.- Published
- 2020
- Full Text
- View/download PDF
36. Renal cholesterol crystal embolism in the setting of warfarin use.
- Author
-
Munawar T, Ibe U, Jiwa N, and Raissi S
- Subjects
- Aged, Diagnosis, Differential, Embolism, Cholesterol chemically induced, Gastrointestinal Hemorrhage chemically induced, Humans, Male, Muscle Weakness etiology, Nephritis, Interstitial chemically induced, Venous Thrombosis drug therapy, Anticoagulants adverse effects, Embolism, Cholesterol diagnosis, Gastrointestinal Hemorrhage diagnosis, Nephritis, Interstitial diagnosis, Warfarin adverse effects
- Abstract
A 73-year-old man presented for evaluation of weakness and black tarry stools that occurred 1 day prior to admission. His medical history is significant for diabetes mellitus, stage 3 chronic kidney disease and deep vein thrombosis on warfarin. He was admitted to the hospital and was found to have acute kidney injury and gastrointestinal bleeding due to a supratherapeutic International Normalized Ratio. His hospital course was complicated by persistent decline in his renal function. He was given intravenous fluid resuscitation, fresh frozen plasma and packed red blood cells for his acute blood loss anaemia. Urinalysis was consistent with acute tubular necrosis. Given the persistent rise in creatinine, a kidney biopsy was obtained, and was significant for mild inflammatory changes, without evidence of vasculitis or allergic interstitial nephritis. Histopathological examination with tissue fixation revealed cholesterol embolisation. Given that he had no recent endovascular procedure or instrumentation, this atheroembolic event was attributed to his warfarin use., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2019
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.