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3. Comprehensive management of risk factors in peripheral vascular disease. Expert consensus

Author

Aicart Bort, Mª Dolores, Almagro Múgica, Fátima, Arrarte Esteban, Vicente Ignacio, Ayala Vigueras, Isabel, Barquilla García, Alfonso, Bellido Castañeda, Virginia, Berenguel Senén, Alejandro, Blanco Echevarría, Agustín, Botana López, Manuel Antonio, Brea Hernando, Ángel, Brito Banfiel, Miguel, Calsina Juscafresa, Laura, Cánovas Molina, María Gloria, Carbayo Herencia, Julio Antonio, Carrasco Carrasco, Eduardo, Carro, Amelia, Casañas Martínez, Marta, Castilla-Guerra, Luis, Cepeda Rodrigo, José María, Cinza-Sanjurjo, Sergio, Clarà, Albert, Comas Samper, José Manuel, Cordero, Alberto, Cosin Sales, Juan, de Juan Bagudá, Javier, de la Fuente, Natalia, Delgado, Elías, Doiz Artázcoz, Esther, Durán Martínez, María, Escalada, Javier, Escobar Cervantes, Carlos, Escribano Pardo, Daniel, Estallo Laliena, Luis, Félix Redondo, Francisco Javier, Fernández Pardo, Jacinto, Rodriguez-Lacin, Jose María Fernández, Ferrer García, Juan Carlos, Frías Vargas, Manuel, Galarza Tapia, Andrés, García León, Andrés, García Lerín, Aurora, García-Martín, Lisardo, Gargallo Fernández, Manuel, Gil, Inés Gil, Girbés Borrás, Juan, Guerra Requena, Mercedes, Guijarro Herraiz, Carlos, Hernández Martínez, Antonio Miguel, Hevia, Sergio, Ibarretxe Gerediaga, Daiana, Iborra Ortega, Elena, Jansen Chaparro, Sergio, Jarauta Simón, Estíbaliz, Jericó Alba, Carlos, Jiménez Muñoz, Beatriz, Lahoz, Carlos, Leiva Hernando, Luis, León Mazorra, Magdalena, López Valverde, María Eugenia, Lorente Calvo, Rosario, Martín Cañuelo, Jorge Jesús, Martínez Hervas, Sergio, Martínez López, María Ángeles, Masmiquel, Luis, Matía Cubillo, Ángel Carlos, Medina Falcón, Agustín, Merino Lanza, Esther, Morales-Pérez, Francisco M., Morata Barrado, Pilar Caridad, Moreno-Pérez, Óscar, Morillas Bueno, Miren, Mosquera Lozano, Jose Daniel, Muñiz Grijalvo, Ovidio, Muñoz Rivas, Núria, Navas de Solís, María Soledad, Obaya Rebollar, Juan Carlos, Ortega, Emilio, Pallarés-Carratalá, Vicente, Párraga Martínez, Ignacio, Pascual Fuster, Vicente, Peinado Adiego, Carmen, Pereira López, Eva María, Pérez Lázaro, M. Antonia, Pérez Pérez, Antonio, Pinés Corrales, Pedro J., Polo García, Jose, Prieto Díaz, Miguel Ángel, Quindimil Vázquez, José Antonio, Rama Martínez, Teresa, Reyes García, Rebeca, Ripoll Vera, Tomás, Rodilla Sala, Enrique, Rodríguez Piñero, Manuel, de Buruaga, Víctor Rodríguez Sáenz, Ruiz García, Antonio, Ruiz Ortiz, Martín, Ruiz Palomar, José Manuel, Saltijeral Cerezo, Adriana, Álvarez, Julio Sánchez, Ortiga, Ruth Sánchez, Sánchez-Hernández, Rosa María, Santos Altozano, Carlos, Seoane Vicente, Maria, Suárez Tembra, Manuel, Tejera Pérez, Cristina, Toledo Frías, Pablo Antonio, Turégano Yedro, Miguel, Valdivielso, Pedro, Valls-Roca, Francisco, de Ceniga, Melina Vega, Velasco Valdazo, Elisa, Vidal-Pérez, Rafael, Zamora Cervantes, Alberto, Barrios, V., Beato, P., Brotons, C., Campuzano, R., Merino-Torres, J.F., Mostaza, J.M., Plana, N., Rubio, J.A., and Comellas, M.

Published
2022
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4. Low Muscle Strength Assessed with Dynamometry in Elderly Polypathological Patients with Acute Heart Failure: PROFUND-IC Registry.

Author

Guzmán-Carreras, Alicia, San Miguel-Agudo, Jorge, Paz-Cabezas, Mateo, Bernabeu-Wittel, Máximo, Muñoz-Rivas, Nuria, Sánchez-Sauce, Beatriz, Aguilar-Rodríguez, Fernando, Cabeza-Osorio, Luis, Andrès, Emmanuel, Lorenzo-Villalba, Noel, and Méndez-Bailón, Manuel

Subjects
MYOCARDIUM, MUSCLE strength, LOGISTIC regression analysis, HEART failure patients, OLDER patients
Abstract

Background: Sarcopenia is a comorbidity associated with heart failure, which aggravates its prognosis. Objectives: To analyze the differential characteristics of polypathological patients with acute heart failure (AHF) based on the presence of low muscle strength, as well as to study whether this condition is associated with a worse prognosis. Methods: An observational study of 377 patients with a diagnosis of acute heart failure from the prospective multicentric PROFUND-IC registry was carried out. The main variable is low muscle strength, which is assessed with dynamometry or prehensile strength. Epidemiological and anthropometric characteristics, as well as associated comorbidities, were analyzed. Likewise, the etiology of the AHF episode, the number of admissions in the previous year, and the NYHA scale were also included. Finally, scores on functionality, treatment established, and mortality and readmission rates were studied. Quantitative variables are described as mean, and standard deviation, and qualitative variables are expressed as absolute numbers and percentages. A descriptive and bivariate analysis was performed according to the presence of low muscle strength (handgrip <27 kg in men and <16 kg in women), using the Welch test for quantitative measures and Chi-square for qualitative variables. In addition, Kaplan-Meier curves of readmission and mortality and a logistic regression analysis were also performed. Results: 377 patients were included (56% female, mean age 83 years). 310 (82.23%) had low muscle strength. Those with low muscle strength were older (84 vs. 78 years, p < 0.001), with more cognitive impairment (11.9% vs. 0%, p = 0.021), worse functional class (p = 0.016), lower scores in the Barthel index and Rockwood scale (p < 0.001), and higher in the PROFUND index (p < 0.001). They had higher rates of readmission and mortality without statistically significant differences. The PROFUND index is significantly associated with low muscle strength (OR 1.19, CI (1.09–1.31), p < 0.001). Conclusions: Elderly polypathological patients with acute heart failure and low muscle strength have a higher PROFUND index and a lower probability of survival per year. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Transcatheter aortic valve implantation and surgical aortic valve replacement among hospitalized patients with and without type 2 diabetes mellitus in Spain (2014-2015)

Author

Méndez Bailón, Manuel, Lorenzo Villalba, Noel, Muñoz Rivas, Nuria, Miguel Yanes, José María De, Miguel Díez, Javier De, Comín Colet, Josep, Hernández Barrera, Valentín, Jiménez García, Rodrigo, López De Andrés, Ana Isabel, Méndez Bailón, Manuel, Lorenzo Villalba, Noel, Muñoz Rivas, Nuria, Miguel Yanes, José María De, Miguel Díez, Javier De, Comín Colet, Josep, Hernández Barrera, Valentín, Jiménez García, Rodrigo, and López De Andrés, Ana Isabel

Abstract

Background: Type 2 diabetes mellitus (T2DM) is strongly related to the in‑hospital and short‑term prognosis in patients with cardiovascular diseases needing surgical or invasive interventions. How T2DM might influence the treatment of aortic stenosis (AS) has not been completely elucidated for surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI). The aims of this study were: (1) to describe the use of aortic valve replacement procedures (TAVI and SAVR) among hospitalized patients with and without T2DM; and (2) to identify fac‑tors associated with in hospital mortality (IHM) among patients undergoing these procedures.Methods: We analyzed data from the Spanish National Hospital Discharge Database between January 1, 2014 and December 31, 2015 for patients aged≥ 40 years. We selected patients whose medical procedures included TAVI (ICD‑9‑CM codes 35.05, 35.06) and SAVR (ICD‑9‑CM codes 35.21, 35.22). We stratified each cohort by diabetes status: T2DM (ICD‑9‑CM codes 250.x0, 250.x2) and no diabetes. We retrieved data about specific comorbidities, risk factors, proce‑dures, and specific in‑hospital postoperative complications. Hospital outcome variables included IHM, and length of hospital stay (LOHS).Results: We identified a total of 2141 and 16,013 patients who underwent TAVI (n= 715; 33.39% with T2DM) and SAVR (n= 4057; 25.33% with T2DM). In patients who underwent TAVI we found no differences in IHM (3.64% in T2DM vs. 5.12% in non‑T2DM, p= 0.603). In the cohort of SAVR, mean LOHS was significantly lower in patients with T2DM than in non‑diabetic patients (13.77 vs. 17.27 days). IHM was lower in patients with T2DM (4.36% vs. 6.31%, p < 0.01). After multivariable adjustment for both procedures, patients with T2DM had significantly lower IHM than patients without diabetes (adjusted OR 0.60; IC 95% 0.37–0.99 for TAVI and adjusted OR 0.80; IC 95% 0.66‑0‑96 for SAVR).Conclusions: T2DM diabetic patients with AS undergoing a valvular replac, Instituto de Salud Carlos III, Unión Europea, Grupo de Excelencia Investigadora URJC-Banco Santander, Depto. de Medicina, Fac. de Medicina, TRUE, pub

Published
2024

8. Opportunity window: vascular risk prevention in women. Adverse pregnancy outcomes and risk of vascular disease. Consensus document of the Spanish Society of Obstetrics and Gynecology (SEGO) and the Spanish Interdiscuplinary Committee for Vascular Preventi

Author

Goya, María, primary, Miserachs, Marta, additional, Suy Franch, Anna, additional, Burgos, Jorge, additional, de la Calle, María, additional, Brotons, Carlos, additional, Castellanos, María del Mar, additional, Cortés, Olga, additional, Díaz Rodríguez, Ángel, additional, Elosúa, Roberto, additional, Freijo, María del Mar, additional, González Fondado, María, additional, Gorostidi, Manuel, additional, Grau, María, additional, Hernández Martínez, Antonio M., additional, Lahoz, Carlos, additional, Muñoz-Rivas, Nuria, additional, Pallarés-Carratalá, Vicente, additional, Pedro-Botet, Juan, additional, Rodilla, Enrique, additional, Royo-Bordonada, Miguel Ángel, additional, Santamaría, Rafael, additional, Torres Fonseca, Mónica, additional, Velescu, Alina, additional, Zamora, Alberto, additional, and Armario, Pedro, additional

Published
2024
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14. External validation of the CHEDDAR score for suspected pulmonary embolism in patients with SARS-CoV-2 infection in an independent cohort.

Author

Franco-Moreno, Anabel, Palma-Huerta, Elena, Fernández-Vidal, Elisa, Madroñal-Cerezo, Elena, Marco-Martínez, Javier, Romero-Pareja, Rodolfo, Izquierdo-Martínez, Aida, Carpintero-García, Lorena, Ruiz-Giardín, José Manuel, Torres-Macho, Juan, de Ancos-Aracil, Cristina Lucía, Brown-Lavalle, David, Muñoz-Rivas, Nuria, Moya-Mateo, Eva, Bellver-Álvarez, María Teresa, Bustamante-Fermosel, Ana, Campos-Rebollo, Carmen, García-Lorente, María, Pagai-Valcárcel, Idoia, and Pedrero-Tomé, Roberto

Abstract

The accuracy of the classic scores that help stratify the pretest clinical probability of pulmonary embolism (PE) in SARS-CoV-2 infection (COVID-19) is low. Therefore, to estimate the risk of PE in these patients, a new set of guidelines must be established. The recently published CHEDDAR score proposes a new diagnostic strategy to reduce the use of computed tomography pulmonary angiography (CTPA) in non-critically ill SARS-COV-2 patients with suspected PE. According to the nomogram, patients are segregated into low-risk (< 182 points) or high-risk (≥ 182 points) based on the best cut-off value to discard PE in the original cohort. We aimed to externally validate this diagnostic strategy in an independent cohort. We analyzed data from two retrospective cohorts of hospitalized non-critically ill COVID-19 patients who underwent a CTPA due to suspicion for PE. CHEDDAR score was applied. As per the CHEDDAR nomogram, patients were classified as having a low or high clinical pre-test probability. Of the 270 patients included, 69 (25.5%) had PE. Applying the CHEDDAR score, 182 (67.4%) patients could have had PE excluded without imaging. Among 58 patients classified as having high clinical pre-test probability, 39 (67.2%) had PE. Sensitivity, specificity, positive and negative predictive values, and AUC were 56%, 90%, 67%, 85%, and 0.783 (95% CI 0.71–0.85), respectively. We provide external validation of the CHEDDAR score in an independent cohort. Even though the CHEDDAR score showed good discrimination capacity, caution is required in patients classified as having low clinical pre-test probability with a D-dimer value > 3000 ng/mL, and a RALE score ≥ 4. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Clinical Characteristics and Prognostic Impact of Short Physical Performance Battery in Hospitalized Patients with Acute Heart Failure—Results of the PROFUND-IC Registry

Author

López-García, Lidia, primary, Lorenzo-Villalba, Noel, additional, Molina-Puente, Juan Igor, additional, Kishta, Aladin, additional, Sanchez-Sauce, Beatriz, additional, Aguilar-Rodriguez, Fernando, additional, Bernanbeu-Wittel, Máximo, additional, Muñoz-Rivas, Nuria, additional, Soler-Rangel, Llanos, additional, Fernández-Carmena, Luis, additional, Andrès, Emmanuel, additional, Deodati, Francesco, additional, Trapiello-Valbuena, Francisco, additional, Casasnovas-Rodríguez, Pilar, additional, López-Reboiro, Manuel Lorenzo, additional, and Méndez-Bailon, Manuel, additional

Published
2023
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25. Prediction of Venous Thromboembolism in Patients With Cancer Using Machine Learning Approaches: A Systematic Review and Meta-Analysis.

Author

Franco-Moreno, Anabel, Madroñal-Cerezo, Elena, Muñoz-Rivas, Nuria, Torres-Macho, Juan, Ruiz-Giardín, José Manuel, and Ancos-Aracil, Cristina L.

Subjects
THROMBOEMBOLISM, CANCER patients, MACHINE learning, PREDICTION models, FORECASTING
Abstract

PURPOSE: Recent studies have suggested that machine learning (ML) could be used to predict venous thromboembolism (VTE) in cancer patients with high accuracy. METHODS: We aimed to evaluate the performance of ML in predicting VTE events in patients with cancer. PubMed, Web of Science, and EMBASE to identify studies were searched. RESULTS: Seven studies involving 12,249 patients with cancer were included. The combined results of the different ML models demonstrated good accuracy in the prediction of VTE. In the training set, the global pooled sensitivity was 0.87, the global pooled specificity was 0.87, and the AUC was 0.91, and in the test set 0.65, 0.84, and 0.80, respectively. CONCLUSION: The prediction ML models showed good performance to predict VTE. External validation to determine the result's reproducibility is necessary. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Efficacy and Safety of Tinzaparin in Prophylactic, Intermediate and Therapeutic Doses in Non-Critically Ill Patients Hospitalized with COVID-19: The PROTHROMCOVID Randomized Controlled Trial

Author

Muñoz-Rivas, Nuria, primary, Aibar, Jesús, additional, Gabara-Xancó, Cristina, additional, Trueba-Vicente, Ángela, additional, Urbelz-Pérez, Ana, additional, Gómez-Del Olmo, Vicente, additional, Demelo-Rodríguez, Pablo, additional, Rivera-Gallego, Alberto, additional, Bosch-Nicolau, Pau, additional, Perez-Pinar, Montserrat, additional, Rios-Prego, Mónica, additional, Madridano-Cobo, Olga, additional, Ramos-Alonso, Laura, additional, Alonso-Carrillo, Jesús, additional, Francisco-Albelsa, Iria, additional, Martí-Saez, Edelmira, additional, Maestre-Peiró, Ana, additional, Méndez-Bailón, Manuel, additional, Hernández-Rivas, José Ángel, additional, and Torres-Macho, Juan, additional

Published
2022
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30. Clinical Characteristics, Management, and In-Hospital Mortality in Patients with Heart Failure with Reduced Ejection Fraction According to Sex and the Presence of Type 2 Diabetes Mellitus

Author

Méndez-Bailón, Manuel, primary, Lorenzo-Villalba, Noel, additional, Jiménez-García, Rodrigo, additional, Hernández-Barrera, Valentin, additional, de Miguel-Yanes, Jose María, additional, de Miguel-Diez, Javier, additional, Muñoz-Rivas, Nuria, additional, Andrès, Emmanuel, additional, and Lopez-de-Andrés, Ana, additional

Published
2022
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31. The influence of sex on ischemic stroke incidence, therapeutic procedures and in‐hospital mortality: Results of the Spanish National Hospital Discharge

Author

Miguel‐Yanes, José M., primary, Jiménez‐García, Rodrigo, additional, López‐de‐Andrés, Ana, additional, Hernández‐Barrera, Valentín, additional, Miguel‐Díez, Javier, additional, Méndez‐Bailón, Manuel, additional, Muñoz‐Rivas, Nuria, additional, Pérez‐Farinós, Napoleón, additional, and Lopez‐Herranz, Marta, additional

Published
2021
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32. Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism

Author

Bikdeli, Behnood, primary, Jiménez, David, additional, del Toro, Jorge, additional, Piazza, Gregory, additional, Rivas, Agustina, additional, Fernández‐Reyes, José Luis, additional, Sampériz, Ángel, additional, Otero, Remedios, additional, Suriñach, José María, additional, Siniscalchi, Carmine, additional, Martín‐Guerra, Javier Miguel, additional, Castro, Joaquín, additional, Muriel, Alfonso, additional, Lip, Gregory Y. H., additional, Goldhaber, Samuel Z., additional, Monreal, Manuel, additional, Prandoni, Paolo, additional, Brenner, Benjamin, additional, Farge‐Bancel, Dominique, additional, Barba, Raquel, additional, Di Micco, Pierpaolo, additional, Bertoletti, Laurent, additional, Schellong, Sebastian, additional, Tzoran, Inna, additional, Reis, Abilio, additional, Bosevski, Marijan, additional, Bounameaux, Henri, additional, Malý, Radovan, additional, Verhamme, Peter, additional, Caprini, Joseph A., additional, Bui, Hanh My, additional, Adarraga, María Dolores, additional, Agud, María, additional, Aibar, Jesús, additional, Aibar, Miguel Ángel, additional, Amado, Cristina, additional, Arcelus, Juan Ignacio, additional, Baeza, Carlos, additional, Ballaz, Aitor, additional, Barbagelata, Cristina, additional, Barrón, Manuel, additional, Barrón‐Andrés, Belén, additional, Blanco‐Molina, Ángeles, additional, Botella, Ernesto, additional, Camon, Ana María, additional, Cañas, Inmaculada, additional, Casado, Ignacio, additional, Chasco, Leyre, additional, Criado, Juan, additional, de Ancos, Cristina, additional, de Miguel, Javier, additional, Demelo‐Rodríguez, Pablo, additional, Díaz‐Peromingo, José Antonio, additional, Di Campli, Mario Virgilio, additional, Díez‐Sierra, Javier, additional, Domínguez, Irene Milagros, additional, Escribano, José Carlos, additional, Falgá, Conxita, additional, Farfán‐Sedano, Ana Isabel, additional, Fernández‐Capitán, Carmen, additional, Fernández‐Reyes, Jose Luis, additional, Fidalgo, María Ángeles, additional, Flores, Katia, additional, Font, Carme, additional, Font, Llorenç, additional, Francisco, Iria, additional, Gabara, Cristina, additional, Galeano‐Valle, Francisco, additional, Galindo, David, additional, García, María Angelina, additional, García‐Bragado, Ferrán, additional, García de Herreros, Marta, additional, García‐Hernáez, Raquel, additional, García‐Mullor, María Mar, additional, García‐Raso, Arantxa, additional, Gavín‐Sebastián, Olga, additional, Gil‐Díaz, Aida, additional, Gómez‐Cuervo, Covadonga, additional, Grau, Enric, additional, Guirado, Leticia, additional, Gutiérrez, Javier, additional, Hernández‐Blasco, Luis, additional, Hernando, Elena, additional, Herreros, Miguel, additional, Jara‐Palomares, Luis, additional, Jaras, María Jesús, additional, Jiménez, Rafael, additional, Joya, Maria Dolores, additional, León, José Manuel, additional, Lima, Jorge, additional, Llamas, Pilar, additional, Lobo, José Luis, additional, López‐Jiménez, Luciano, additional, López‐Miguel, Patricia, additional, López‐Núñez, Juan José, additional, López‐Reyes, Raquel, additional, López‐Ruiz, Antonio, additional, López‐Sáez, Juan Bosco, additional, Lorenzo, Alicia, additional, Madridano, Olga, additional, Maestre, Ana, additional, Marchena, Pablo Javier, additional, Martín del Pozo, Mar, additional, Martín‐Martos, Francisco, additional, Mella, Carmen, additional, Mellado, Meritxell, additional, Mercado, Maria Isabel, additional, Moisés, Jorge, additional, del Valle Morales, María, additional, Muñoz‐Blanco, Arturo, additional, Muñoz‐Rivas, Nuria, additional, Navas, María Sierra, additional, Nieto, Jose Antonio, additional, Núñez‐Fernández, Manuel Jesús, additional, Obispo, Berta, additional, Olid, Mónica, additional, Olivares, María Carmen, additional, Orcastegui, José Luis, additional, Ortega‐Michel, Clara, additional, Osorio, Jeisson, additional, Otalora, Sonia, additional, Parra, Pedro, additional, Parra, Virginia, additional, Pedrajas, José María, additional, Pellejero, Galadriel, additional, Porras, José Antonio, additional, Portillo, José, additional, Riera‐Mestre, Antoni, additional, Rivera‐Civico, Francisco, additional, Rodríguez‐Chiaradía, Diego Agustín, additional, Rodríguez‐Cobo, Ana, additional, Rodríguez‐Matute, Consolación, additional, Rogado, Jacobo, additional, Roig, Sonia, additional, Rosa, Vladimir, additional, Ruiz‐Artacho, Pedro, additional, Ruiz‐Giménez, Nuria, additional, Ruiz‐Ruiz, Justo, additional, Ruiz‐Sada, Pablo, additional, Salgueiro, Giorgina, additional, Sánchez‐Martínez, Rosario, additional, Sánchez‐Muñoz‐Torrero, Juan Francisco, additional, Sancho, Teresa, additional, Sirisi, Merçe, additional, Soler, Silvia, additional, Tirado, Raimundo, additional, Torres, María Isabel, additional, Tolosa, Carles, additional, Trujillo‐Santos, Javier, additional, Uresandi, Fernando, additional, Valero, Beatriz, additional, Valle, Reina, additional, Vela, Jerónimo Ramón, additional, Vidal, Gemma, additional, Villares, Paula, additional, Zamora, Carles, additional, Gutiérrez, Paula, additional, Vázquez, Fernando Javier, additional, Engelen, Matthias, additional, Vanassche, Thomas, additional, Hirmerova, Jana, additional, Salgado, Estuardo, additional, Ait Abdallah, Nassim, additional, Bura‐Riviere, Alessandra, additional, Crichi, Benjamin, additional, Debourdeau, Philippe, additional, Olivier, Espitia, additional, Falvo, Nicolas, additional, Galliazzo, Silvia, additional, Helfer, Hélène, additional, Mahé, Isabelle, additional, Moustafa, Farès, additional, Poenou, Geraldine, additional, Braester, Andrei, additional, Bilora, Franca, additional, Bucherini, Eugenio, additional, Ciammaichella, Maurizio, additional, Imbalzano, Egidio, additional, Maida, Rosa, additional, Mastroiacovo, Daniela, additional, Pace, Federica, additional, Pesavento, Raffaele, additional, Pomero, Fulvio, additional, Quintavalla, Roberto, additional, Rocci, Anna, additional, Romualdi, Roberta, additional, Tufano, Antonella, additional, Visonà, Adriana, additional, Zalunardo, Beniamino, additional, Gibietis, Valdis, additional, Kigitovica, Dana, additional, Skride, Andris, additional, Fonseca, Samuel, additional, Martins, Filipa, additional, Meireles, Jose, additional, Mazzolai, Lucia, additional, Bikdeli, Behnood, additional, Tafur, Alfonso J., additional, Ochoa‐Chaar, Cassius Iyad, additional, Weinberg, Ido, additional, and Wilkins, Hannah, additional

Published
2021
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33. Incidence and Outcomes of Hemorrhagic Stroke among Adults in Spain (2016–2018) According to Sex: A Retrospective, Cohort, Observational, Propensity Score Matched Study

Author

de Miguel-Yanes, Jose M., primary, Lopez-de-Andres, Ana, additional, Jimenez-Garcia, Rodrigo, additional, Hernandez-Barrera, Valentin, additional, de Miguel-Diez, Javier, additional, Méndez-Bailón, Manuel, additional, Pérez-Farinós, Napoleón, additional, Muñoz-Rivas, Nuria, additional, Carabantes-Alarcon, David, additional, and López-Herranz, Marta, additional

Published
2021
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34. Renal infaction in a patient with COVID-19

Author

Cuevas Tascón, Guillermo, Salazar Chiriboga, Danilo E., Lorente Ramos, Rosa, Díaz Díaz, Domingo, Rodríguez Ruiz, Covadonga, Procaccini, Fabio L., Torres Aguilera, Esther, Martín Navarro, Juan A., Mestre Gómez, Beatriz, Muñoz Rivas, Nuria, and Alcázar Arroyo, Roberto

Published
2021
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35. Infarto renal en paciente con COVID-19

Author

Cuevas Tascón, Guillermo, Salazar Chiriboga, Danilo E., Lorente Ramos, Rosa, Díaz Díaz, Domingo, Rodríguez Ruiz, Covadonga, Procaccini, Fabio L., Torres Aguilera, Esther, Martín Navarro, Juan A., Mestre Gómez, Beatriz, Muñoz Rivas, Nuria, and Alcázar Arroyo, Roberto

Published
2021
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36. Incidence of Thromboembolic Events in Cancer Hospitalized Patients With COVID-19

Author

Rogado, Jacobo, primary, Obispo, Berta, additional, Muñoz-Rivas, Nuria, additional, Lara, Miguel Angel, additional, Mestre-Gómez, B., additional, Lorente-Ramos, R.M., additional, Rogado, J., additional, Franco-Moreno, A., additional, Obispo, B., additional, Salazar-Chiriboga, D., additional, Saez-Vaquero, T., additional, Torres-Macho, J., additional, Abad-Motos, A., additional, Cortina-Camarero, C., additional, Such-Diaz, A., additional, Ruiz-Velasco, E., additional, Muñoz-Rivas, N., additional, Sierra-Hidalgo, F., additional, Moya-Mateo, E., additional, de Carranza-López, M., additional, Herrera-Morueco, M.A., additional, Akasbi-Montalvo, M., additional, Pardo-Guimerá, V., additional, Medrano-Izquierdo, P., additional, Mariscal-Gómez, E., additional, Marín-Mori, K., additional, Figueras-González, C., additional, López-Lallave, S., additional, Díaz-Díaz, D., additional, Mauleón-Fernández, C., additional, Martín-Navarro, J., additional, Torres-Rubio, P., additional, Matesanz, C., additional, Moro-Alvarez, M.J., additional, Bustamante-Fermosel, A., additional, and Hernández-Rivas, J.A., additional

Published
2021
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37. Sex Differences in the Incidence and Outcomes of Acute Myocardial Infarction in Spain, 2016–2018: A Matched-Pair Analysis

Author

de Miguel-Yanes, José M., primary, Jiménez-García, Rodrigo, additional, Hernandez-Barrera, Valentin, additional, de Miguel-Díez, Javier, additional, Muñoz-Rivas, Nuria, additional, Méndez-Bailón, Manuel, additional, Pérez-Farinós, Napoleón, additional, López-Herranz, Marta, additional, and Lopez-de-Andres, Ana, additional

Published
2021
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38. Impact of Systemic Corticosteroids on Mortality in Older Adults With Critical COVID-19 Pneumonia

Author

Piniella-Ruiz, Esther, primary, Bellver-Álvarez, María Teresa, additional, Mestre-Gómez, Beatriz, additional, Escolano-Fernández, Belén, additional, Vinat-Prado, Sara, additional, Cabezas-Olea, Rita, additional, Acedo-Gutiérrez, María Soledad, additional, Akasbi-Montalvo, Mirian, additional, Ryan-Murua, Pablo, additional, Bustamante-Fermosel, Ana, additional, Muñoz-Rivas, Nuria, additional, Santamaría-García, Carmen, additional, Pardo-Guimerá, Virginia, additional, Ulla-Anés, Mariano, additional, Franco-Moreno, Anabel, additional, and Torres-Macho, Juan, additional

Published
2021
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39. Systemic thrombosis in a large cohort of COVID-19 patients despite thromboprophylaxis: A retrospective study

Author

Muñoz-Rivas, Nuria, primary, Abad-Motos, Ane, additional, Mestre-Gómez, Beatriz, additional, Sierra-Hidalgo, Fernando, additional, Cortina-Camarero, Cristina, additional, Lorente-Ramos, Rosa María, additional, Torres-Rubio, Pedro, additional, Arranz-García, Paz, additional, Franco-Moreno, Ana Isabel, additional, Gómez-Mariscal, Eloy, additional, Mauleón-Fernández, Cristina, additional, Alonso-García, Soledad, additional, Rogado, Jacobo, additional, Saez-Vaquero, Teresa, additional, Such-Diaz, Ana, additional, Ryan, Pablo, additional, Moya-Mateo, Eva, additional, Martín-Navarro, Juan A., additional, Hernández-Rivas, Jose Angel, additional, Torres-Macho, Juan, additional, and Churruca, Juan, additional

Published
2021
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40. Trends and Clinical Impact of Gastrointestinal Endoscopic Procedures on Acute Heart Failure in Spain (2002–2017)

Author

Méndez-Bailón, Manuel, primary, Jiménez-García, Rodrigo, additional, Muñoz-Rivas, Nuria, additional, Hernández-Barrera, Valentín, additional, de Miguel-Yanes, José Maria, additional, de Miguel-Díez, Javier, additional, Andrès, Emmanuel, additional, Lorenzo-Villalba, Noel, additional, and López-de-Andrés, Ana, additional

Published
2021
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41. Incidence of Deep Venous Thrombosis in Patients With COVID ‐19 and Pulmonary Embolism

Author

Franco‐Moreno, Anabel, Herrera‐Morueco, Maria, Mestre‐Gómez, Beatriz, Muñoz‐Rivas, Nuria, Abad‐Motos, Ane, Salazar‐Chiriboga, Danilo, Duffort‐Falcó, Mercedes, Medrano‐Izquierdo, Pilar, Bustamante‐Fermosel, Ana, Pardo‐Guimera, Virginia, Ulla‐Anés, Mariano, and Torres‐Macho, Juan

Subjects
Radiological and Ultrasound Technology, Radiology Nuclear Medicine and imaging
Published
2020
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44. Heart Failure Is a Risk Factor for Suffering and Dying of Clostridium difficile Infection. Results of a 15-Year Nationwide Study in Spain

Author

Méndez-Bailón, Manuel, primary, Jiménez-García, Rodrigo, additional, Hernández-Barrera, Valentín, additional, de Miguel-Díez, Javier, additional, de Miguel-Yanes, José M., additional, Muñoz-Rivas, Nuria, additional, Lorenzo-Villalba, Noel, additional, Carabantes-Alarcon, David, additional, Zamorano-León, José J., additional, Astasio-Arbiza, Paloma, additional, Ortega-Molina, Paloma, additional, and López-de-Andrés, Ana, additional

Published
2020
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45. The influence of sex on ischemic stroke incidence, therapeutic procedures and in‐hospital mortality: Results of the Spanish National Hospital Discharge.

Author

de Miguel‐Yanes, José M., Jiménez‐García, Rodrigo, López‐de‐Andrés, Ana, Hernández‐Barrera, Valentín, de Miguel‐Díez, Javier, Méndez‐Bailón, Manuel, Muñoz‐Rivas, Nuria, Pérez‐Farinós, Napoleón, and Lopez‐Herranz, Marta

Abstract

Background: Previous research has revealed sex‐related differences in outcomes for people admitted to hospitals for ischemic stroke. We aimed to analyse the incidence, use of invasive procedures and in‐hospital outcomes of ischemic stroke in Spain (2016‐2018) using the Spanish National Hospital Discharge Database. We sought sex‐related differences in incidence and in‐hospital outcomes over time. Methods: We estimated the incidence of ischemic stroke in men and women. We analysed comorbidities (Charlson's comorbidity index, cardiovascular risk factors, alcohol abuse and atrial fibrillation), procedures (mechanical ventilation, endovascular thrombectomy and thrombolytic therapy) and outcomes. We matched each woman with a man with identical age, type of ischemic stroke and year of hospitalisation. We built Poisson regression models to obtain adjusted incidence rate ratios (IRRs). We tested in‐hospital mortality (IHM) with logistic regression analyses. Results: Ischemic stroke was coded in 172 255 patients aged ≥35 years (92 524 men 53.7%). Men showed higher incidence rates (216.9 vs. 172.3/105; P <.001; IRR = 1.57 (95% CI:1.55‐1.59) than women. After matching, the use of endovascular thrombectomy (5.1% vs. 4.0%; P <.001) and thrombolytic therapy (7.6% vs. 6.8%; P <.001) was higher among women. IHM was significantly higher in women than in matched men (11.2% vs. 10.4%; P <.001). Women had a lower IHM than matched men when endovascular thrombectomy (9.4% vs. 12.1%; P =.001) or thrombolytic therapy (6.7% vs. 8.3%; P =.003) was coded. Patients of both sexes admitted for ischemic stroke who received thrombolytic therapy had lower IHM (OR = 0.76; 95% CI:0.68‐0.85 among men; and OR = 0.58; 95% CI:0.52‐0.64 among women), but endovascular thrombectomy was associated with a lower IHM only among women (OR = 0.58; 95% CI:0.51‐0.66). After multivariable adjusting, women admitted to the hospital for ischemic stroke had a significantly higher IHM than men (OR = 1.16; 95% CI:1.12‐1.21). Conclusion: Men had higher incidence rates of ischemic stroke than women. Women more often underwent thrombolytic therapy and endovascular thrombectomy but had a higher IHM. [ABSTRACT FROM AUTHOR]

Published
2021
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46. MOESM3 of Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical mitral valve replacement in Spain (2001–2015)

Author

López-De-Andrés, Ana, Miguel-Díez, Javier De, Muñoz-Rivas, Nuria, Hernández-Barrera, Valentín, Méndez-Bailón, Manuel, Miguel-Yanes, José De, and Jiménez-García, Rodrigo

Abstract

Additional file 3: Figure S2. Incidence of bioprosthetic mitral valve replacement among type 2 diabetes and non-type 2 diabetes patients in Spain 2001–2015.

Published
2019
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48. Incidence of Deep Venous Thrombosis in Patients With COVID‐19 and Pulmonary Embolism: Compression Ultrasound COVID Study.

Author

Franco‐Moreno, Anabel, Herrera‐Morueco, Maria, Mestre‐Gómez, Beatriz, Muñoz‐Rivas, Nuria, Abad‐Motos, Ane, Salazar‐Chiriboga, Danilo, Duffort‐Falcó, Mercedes, Medrano‐Izquierdo, Pilar, Bustamante‐Fermosel, Ana, Pardo‐Guimera, Virginia, Ulla‐Anés, Mariano, and Torres‐Macho, Juan

Subjects
VENOUS thrombosis, COVID-19, VENOGRAPHY, ULTRASONIC imaging, PULMONARY embolism
Abstract

Objectives: Several reports had observed a high risk of pulmonary embolism (PE) in patients with coronavirus disease 2019 (COVID‐19), most of them in the intensive care unit. Reported findings indicate that a direct viral‐mediated hyperinflammatory response leads to local thromboinflammation. According to those findings, the incidence of deep venous thrombosis (DVT) in patients with COVID‐19 and PE should be low. The objective of this study was to evaluate the incidence of DVT in patients with COVID‐19 who developed PE. Methods: In this prospective observational study, consecutive patients hospitalized in the internal medicine ward with a diagnosis of COVID‐19 who developed PE were screened for DVT in the lower extremities with complete compression ultrasound. Results: The study comprised 26 patients. Fifteen patients (57.7%) were male. The median age was 60 years (interquartile range, 54–73 years). Compression ultrasound findings were positive for DVT in 2 patients (7.7%; 95% confidence interval, 3.6%–11.7%). Patients with DVT had central and bilateral PE. In both, venous thromboembolism was diagnosed in the emergency department, so they did not receive previous prophylactic therapy with low‐molecular‐weight heparin. Patients without DVT had higher median d‐dimer levels: 25,688 μg/dL (interquartile range, 80,000–1210 μg/dL) versus 5310 μg/dL (P <.05). Conclusions: Our study showed a low incidence of DVT in a cohort of patients with COVID‐19 and PE. This observation suggests that PE in these patients could be produced mainly by a local thromboinflammatory syndrome induced by severe acute respiratory syndrome coronavirus 2 infection and not by a thromboembolic event. [ABSTRACT FROM AUTHOR]

Published
2021
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