1. Simultaneous multi-slice readout-segmentation of long variable echo-trains for accelerated diffusion-weighted imaging of nasopharyngeal carcinoma: A feasibility and optimization study
- Author
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Qiuzhi Chen, Chunrong Tu, Xiaoqian Yuan, Xiaoxia Wang, Hesong Shen, Wei Liu, Xiaoqin Li, Renwei Liu, Qing Li, Xing Wang, Jiuquan Zhang, and Daihong Liu
- Subjects
Image quality ,Long Variable ,030218 nuclear medicine & medical imaging ,Scan time ,03 medical and health sciences ,0302 clinical medicine ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Segmentation ,cardiovascular diseases ,Nasopharyngeal Carcinoma ,Acceleration factor ,Echo-Planar Imaging ,business.industry ,Reproducibility of Results ,Nasopharyngeal Neoplasms ,Multi slice ,medicine.disease ,Diffusion Magnetic Resonance Imaging ,Nasopharyngeal carcinoma ,030220 oncology & carcinogenesis ,Feasibility Studies ,Nuclear medicine ,business ,Diffusion MRI - Abstract
Objectives We aimed to evaluate the feasibility of simultaneous multi-slice readout segmentation of long variable echo-trains (SMS-RESOLVE) for diffusion-weighted imaging (DWI) of nasopharyngeal carcinoma (NPC) and determine the optimal acceleration factor of SMS-RESOLVE DWI compared with conventional RESOLVE DWI. Materials and methods One hundred and five patients with histologically confirmed NPC were enrolled. DWIs including conventional RESOLVE DWI, SMS-RESOLVE DWI with acceleration factors of 2 and 3 (2 × SMS-RESOLVE and 3 × SMS-RESOLVE) were acquired at b-values of 0 and 800 s/mm2. The subjective image quality, including overall image quality, lesion conspicuity, and lesion distortion scores, and objective image quality, including signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and contrast in these three protocols, were assessed and compared. The apparent diffusion coefficients (ADCs) of the primary tumor and right masseter muscle and normalized ADCs in the three protocols were measured and compared. Results The 2 × SMS-RESOLVE provided comparable image quality and ADCs with a 48.3% reduction in scan time compared with conventional RESOLVE DWI. The 3 × SMS-RESOLVE showed significantly poorer image quality and the highest ADCs with a 56.9% reduction in scan times compared with conventional RESOLVE DWI. Conclusion The SMS-RESOLVE DWI with an acceleration factor of 2 yielded the best compromise between image quality and scan time reduction and could be an alternative to conventional RESOLVE DWI for nasopharyngeal carcinoma.
- Published
- 2021