1. A Rare Pediatric Case Report With Review of Literature for the Diagnosis of Acute Megakaryoblastic Leukemia (FAB M7)
- Author
-
Gasim Dobie, Khalaf H Alsharif, Muhammed Saboor, Mohammed H Nahari, Abdulrahim R. Hakami, Amr J Halawani, Abdullah Hamadi, Hassan A Hamali, Abdullah A Mobarki, Mohammad Algahtani, Denise E. Jackson, and Abdulrahman Theyab
- Subjects
medicine.medical_specialty ,Down syndrome ,QH301-705.5 ,acute myeloid leukemia ,Easy Bruising ,bone marrow examination ,Acute megakaryoblastic leukemia ,Immunophenotyping ,immunophenotyping ,hemic and lymphatic diseases ,medicine ,Biology (General) ,medicine.diagnostic_test ,business.industry ,Myeloid leukemia ,General Medicine ,medicine.disease ,acute megakaryocytic leukemia ,Dermatology ,Bone marrow examination ,Blood film ,Diarrhea ,Medicine ,medicine.symptom ,business - Abstract
Acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) accounting for 3%–10% of primary AML in childhood. Clinical manifestations of AML patients can include low grade of fever, diarrhea, easy bruising, failure to growth, and life-threatening clinical manifestations. Laboratory tests are very crucial to make a definitive diagnosis and treatment. We report here an uncommon case of AMKL in a 12-month-old boy who presented with general paleness and fatigue. Based on blood film investigation, bone marrow examination report, and immunophenotyping, he was diagnosed as a case of AMKL without Down syndrome.
- Published
- 2021