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The aim of this study is to identify the strengths, weaknesses, opportunities, and threats (SWOT) of science, technology, engineering, art, and mathematics (STEAM) learning at the elementary school level in Makassar. This study employed a mixed methods approach, specifically the QUANqual type of explanatory sequential design. The survey method was used to collect and analyze quantitative data, while interviews and documentation methods were used for qualitative non-numerical data. The respondents consisted of elementary school teachers in Makassar who were selected using simple random sampling. The results showed that using SWOT analysis and internal strategic factors analysis summary-external strategic factors analysis summary (IFAS-EFAS) calculations, the strengths-opportunities (SO) strategy has the highest score of 4.27. In addition, the weaknesses-opportunities (WO), strengths-threats (ST), and weaknesses-threats (WT) strategies received consecutive scores of 3.25, 2.71, and 1.69, respectively. It suggests that STEAM learning in Makassar is in a growth stage due to its strengths and opportunities that support the development of STEAM education in the city.

Mycobacterium avium complex, a commonly seen infection in individuals with a compromised immune system, can also affect people who are immunocompetent. One particularly important manifestation is in elderly females with a competent immune system, involving the middle lobe and lingula lobe of the lung. This is known as Lady Windermere syndrome (LWS). An 84-year-old female patient with certain nonpulmonary comorbidities initially got a diagnosis of MAC infection but refused to undergo any medication therapy, she presents after 5 years for a follow up visit and is found to have significant changes in her pulmonary parenchyma on investigation findings, concerning for this syndrome. LWS is a rather uncommon condition, rarely presents in clinical settings and described very less often in the literature. This report is aimed at increasing awareness of LWS as a possible diagnosis that should be considered in patients with a chronic MAC infection and a specific pattern of parenchymal changes discussed in this report in detail.

Double-j stents are commonly used in many urological procedures to facilitate the drainage of renal systems postoperatively. Their usage has revolutionized the world of urological interventions but if left forgotten present serious complications. We report a case of an old man who was diagnosed with bilaterally fragmented DJ stents in situ in our urology department following his sessions of extracorporeal shock wave lithotripsy for chronic encrustations. These stents were placed after complete breakdown of bilateral ureteral stones through ureterorenoscopy and laser lithotripsy.

Objective To investigate how various morbidities affect older patients’ performance on the Timed Up and Go (TUG) test.Design Cross-sectional study.Setting The seven government hospitals of Lahore, Pakistan, included are major tertiary care centres, representing an older patient population of Punjab, Pakistan.Method 160 elderly participants completed the TUG test, frailty evaluations and Charlson Comorbidity Index (CCI) scoring to assess mobility, frailty and comorbidity burden. The Student’s t-test analysed differences between TUG groups (

This study examines the impact of microwave processing on Kachnar (Bauhinia variegata) powder and its application in flatbreads. Microwave treatment reduced anti-nutrient levels of alkaloids, phytates, tannins, and saponins by 83–90 %, enhancing safety. Incorporation of microwaved kachnar powder (MwKP) into flatbreads at 2.5–10 % replacement levels improved nutritional profiles, with increases in ash (0.4–0.9 g/100 g), dietary fiber (2–3 g/100 g), protein (8–9 g/100 g), and minerals such as Fe (3–4 mg/100 g), Zn (3.2–3.9 mg/100 g), Na (3–10 mg/100 g), K (378–388 mg/100 g), Ca (30–45 mg/100 g), and Mg (125–145 mg/100 g). Antioxidant activity also increased significantly (p

This research work aims to synthesize environmentally benign and cost-effective metal nanoparticles. In this current research scenario, the leaf extract of Cedrela toona was used as a reducing agent to biosynthesize silver nanoparticles (AgNPs). The synthesis of AgNPs was confirmed by the color shift of the reaction mixture, i.e., silver nitrate and plant extract, from yellow to dark brown colloidal suspension and was established by UV-visible analysis showing a surface plasmon resonance band at 434 nm. Different experimental factors were optimized for the formation and stability of AgNPs, and the optimum conditions were found to be 1 mM AgNO3 concentration, a 1:9 ratio of extract/precursor, and an incubation temperature of 70°C for 4 h. The Fourier transform infrared spectroscopy spectra indicated the presence of phytochemicals in the leaf extract that played the role of bioreducing agents in forming AgNPs. X-ray diffraction patterns confirmed the presence of AgNPs with a mean size of 25.9 nm. The size distribution and morphology of AgNPs were investigated by scanning electron microscopy, which clearly highlighted spherical nanoparticles with a size distribution of 22–30 nm with a mean average size of 25.5 nm. Moreover, prominent antibacterial activity was found against Enterococcus faecalis (21 ± 0.5 mm), Bacillus subtilis (20 ± 0.9 mm), Pseudomonas aeruginosa (18 ± 0.3 mm), Staphylococcus aureus (16 ± 0.7 mm), Klebsiella pneumoniae (16 ± 0.3 mm), and Escherichia coli (14 ± 0.7 mm). In addition, antioxidant activity was determined by DPPH and ABTS assays. Higher antioxidant activity was reported in AgNPs compared to the plant extract in both DPPH (IC50 = 69.62 µg·ml−1) and ABTS assays (IC50 = 47.90 µg·ml−1). Furthermore, cytotoxic activity was also investigated by the MTT assay against MCF-7 cells, and IC50 was found to be 32.55 ± 0.05 µg·ml−1. The crux of this research is that AgNPs synthesized from the Cedrela toona leaf extract could be employed as antibacterial, antioxidant, and anticancer agents for the treatment of bacterial, free radical-oriented, and cancerous diseases.

In this study, the polar root extract of Cyperus scariosus R.Br. was used for the biogenic synthesis of ZnO NPs. The results of this study show that ZnO NPs have a spherical structure with an average size of 85.4 nm. The synthesized catalysts were tested for their photocatalytic activity by degrading methyl orange and methylene blue under sunlight. Improved degradation efficiencies of 79.44% and 84.92% were achieved within 120 min. ZnO NPs exhibited strong antibacterial activity against both Gram-positive Listeria monocytogenes (18 mm) and Staphylococcus epidermidis (20 mm) and Gram-negative strains of Escherichia coli (16 mm) and Bordetella bronchiseptica (14 mm), as shown by the inhibition zones, which were comparable to the positive control (ceftriaxone) but larger than the plant root extract. ZnO NPs showed high antioxidant activity, as a ferric-reducing antioxidant power assay value of 66.29 µg (AAE µg·mL−1) and a DPPH value of 57.44 µg (AAE µg·mL−1) were obtained at a concentration of 500 µL, which was higher than those of the C. scariosus root extract. Quantification of the total phenolic and flavonoid content yielded values of 57.63 µg (GAE µg·mL−1) and 70.59 µg (QCE µg·mL−1), respectively. At a concentration of 500 μL (1 mg·mL−1), the tested nanoparticles (NPs) showed a greater anti-inflammatory effect (84.12%) compared to the root extract of C. scariosus (34.39%). Overall, our findings highlight the versatile properties of green synthesized ZnO NPs and demonstrate their potential for environmental remediation and antimicrobial formulations, as well as promising candidates for further investigation in biomedical fields such as drug delivery and therapy.

Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have shown benefits in improving cardiovascular (CV) outcomes in patients with heart failure (HF) and may mitigate symptom progression in myocardial infarction (MI). However, their effectiveness in patients with type 2 diabetes and MI undergoing percutaneous coronary intervention (PCI) is unclear. Methods: To identify eligible studies, a comprehensive search of electronic databases, PubMed, Cochrane Library, Scopus and Embase, was conducted from inception until May 2024. Results were presented as risk ratios (RR) and their corresponding 95 % confidence intervals (CIs). Results: Our analysis included 8 observational studies comprising 24,229 patients. The results indicated that SGLT2i with PCI was associated with a significantly reduced risk of all-cause death (RR=0.61; 95 % CI=0.54 to 0.68), CV death (RR=0.46; 95 % CI=0.22 to 0.94), major adverse cardiovascular events (RR=0.80;95 % CI: 0.66 to 0.96), HF-related hospitalizations (RR=0.63; 95 % CI=0.44 to 0.90), stroke (RR=0.77; 95 % CI: 0.62 to 0.96) and acute kidney injury (RR=0.46; 95 % CI: 0.25 to 0.84) compared to PCI without SGLT2i use. However, the risk of revascularization remained comparable between the groups. Conclusion: Our study demonstrates that SGLT2i with PCI in patients with type 2 diabetes and MI are associated with improved CV outcomes compared to PCI without SGLT2i use. Randomized controlled trials are required to confirm the improvement in outcomes with SGLT2i therapy combined with PCI in patients with MI and diabetes.

The conversion of bioresources like Spirulina platensis (SP) into value-added chemicals, such as methanol, offers a sustainable replacement of fossil fuels and contributes to greenhouse gas mitigation. This study presents an integrated process simulation model, developed using Aspen Plus v10®, for the steam gasification of SP and subsequent methanol production. Process parameters, including temperature range from 650-950 °C, steam/feed ratio from 0.5–2, and recycle ratio from 0–9, were investigated to optimize syngas composition and methanol yield. Results demonstrated that increasing temperature enhances H2 and CO production while reducing CO2 and CH4, significantly increasing methanol production from 6500 to 9500 kg/h. The steam/feed ratio also influences syngas composition and methanol yield, with higher ratios promoting H2 and CO2 production and reducing CO and CH4. The economic evaluation of two scenarios, a base case and an optimum case, shows that the capital expenditure (Capex) and operating expenditure (Opex) are 19.3M$ and 9.07M$ for the base case, and 20.018M$ and 10.21M$ for the optimum case. The analysis also reveals that the optimum case, with higher methanol production (7.2 tonnes/h compared to 6.7 tonnes/h in the base case), generates a higher net income (9.76 M$/y) and reduces CO2 emissions (4.918 tonnes CO2-e/y compared to 5.72 tonnes CO2-e/y). The energy flow indicates the input energy requirement, the energy carried by methanol, and the surplus energy, totalling 26740 kW to meet the major system's energy demands. This study provides valuable insights for researchers, policymakers, and commercial entities seeking to develop sustainable and economically viable biofuel production processes.

Metacognition is the ability to think about thinking. One of the learning models in geometry is the van Hiele model, which consists of learning phases and geometry thinking level. However, geometry learning strategy in Indonesia does not stress metacognition and geometry thinking level. Hence, this study aims to examine the effectiveness of geometry learning strategy based on the infusion of metacognition in van Hiele model compared to van Hiele learning phases in helping secondary school students to improve their geometry thinking level. The quasi-experimental study was conducted six-week with 90 students. The students selected purposively divided into two groups, with 30 students in both treatment groups, respectively. The instrument employed van Hiele Geometry Test (vHGT) before and after the treatment to measure the student's geometry thinking level. Data were in ordinal form analyzed descriptively and inferentially using Mann-Whitney U. The result revealed the significant difference between the final geometry thinking level in both groups. Thus, it can be concluded that the geometry learning strategy based on the infusion of metacognition in van Hiele model is more effective in improving the student's geometry thinking level than the geometry learning strategy based on van Hiele model.

Metacognition, or the ability to think about thinking, is essential in the development of geometric thinking. However, studies on the Van Hiele model and the application of metacognition on geometric thinking are still under-researched. This study aimed to provide a review of the Van Hiele model and the application of metacognition on geometric thinking. A total of 844 articles were retrieved through internet search engines from 1995 to 2020 and manually selected and reviewed systematically. The keywords used related to the Van Hiele model, metacognition, and geometric thinking. The findings that emerged from the review were categorized into two main themes which were the effectiveness of the Van Hiele model towards geometric thinking and the effectiveness of the application of metacognition on geometric thinking. Most articles revealed the positive indication of the geometric thinking development through the Van Hiele model intervention. It also seems that the potential of the application of metacognition in the Van Hiele model can strengthen geometric thinking development. Researchers and educators may find this knowledge useful in conducting empirical studies and developing learning instructions based on the application of metacognition in the development of geometric thinking.

This study examines the association between serum Sestrin2 (SESN2) levels and cardiovascular disease (CVD) risk factors in healthy and diabetic adults, using data from the Qatar Biobank (QBB). A total of 844 participants were included, with 518 in the diabetic cohort and 326 in the healthy cohort. Clinical characteristics, cardiometabolic markers, and SESN2 levels were measured, and binomial logistic regression analyses were conducted to assess the associations between SESN2 and various health indices. Diabetic patients had significantly lower SESN2 levels compared to healthy controls (5.49 ± 5.94 vs 8.25 ± 7.57 ng/mL, P < 0.001). A significant negative correlation was observed between SESN2 and HbA1c (−0.19, P = 0.0006), insulin (−0.19, P = 0.0006), HOMA-IR (−0.17, P = 0.0024), C-peptide (−0.18, P = 0.0012), triglycerides (TG)/HDL ratio (−0.12, P = 0.0283), and the pulsatility index (PI) (−0.15, P = 0.006). In healthy individuals, higher SESN2 levels were associated with lower odds of elevated HbA1c (adjusted odds ratio [AOR] = 0.33, P = 0.00), insulin (AOR = 0.23, P = 0.00), HOMA-IR (AOR = 0.58, P = 0.06), C-peptide (AOR = 0.56, P = 0.04), and TG (AOR = 0.37, P = 0.03). In contrast, diabetic patients showed a positive correlation between SESN2 and insulin (0.15, P = 0.0005), HOMA-IR (0.11, P = 0.0106), and C-peptide (0.12, P = 0.0048). Participants in the highest SESN2 tertile had increased risks for high BMI (AOR = 1.96, P = 0.05), high TG (AOR = 1.57, P = 0.04), high NT-proBNP (AOR = 7.27, P = 0.01), and high fibrinogen (AOR = 1.92, P = 0.03). These findings suggest that while high SESN2 levels are cardioprotective in healthy individuals, they may indicate higher cellular stress in diabetics. Determining optimal SESN2 levels could help assess CVD risk, particularly in diabetic patients.

Sistem Pembahagian Pintar untuk Kumpulan Kuliah Pelajar (SmartAISystem) merupakan sistem berasaskan web yang dapat membuat proses pembahagian pelajar ke kumpulan mengikut kriteria-kriteria tertentu. Sistem ini merupakan satu penyelesaian untuk mengatasi masalah yang timbul daripada kaedah manual yang digunakan oleh Pusat Asasi Pertahanan (PAP) UPNM. Penggunaan kaedah manual untuk mengendalikan data mentah pelajar yang diterima daripada Unit Pusat Universiti (UPU) cenderung untuk menimbulkan masalah kesilapan manusia. Selain itu, proses pembahagian ini mengambil masa yang lebih lama dari tempoh jangkaan penyediaan yang sepatutnya. Pembahagian pelajar mengikut kumpulan kuliah secara manual yang digunapakai sebelum ini memerlukan tenaga kerja yang ramai bagi mengurangkan kesilapan. SmartAISystem dibangunkan berdasarkan model Rapid Application Development (RAD). Sistem ini membolehkan staf melakukan pembahagian kumpulan kuliah pelajar secara sistematik di atas talian. Bagi perisian dan perkakasan, SmartAISystem menggunakan HTML, CSS dan JavaScript untuk membangunkan SmartAISystem. Selain itu, MySQL digunakan sebagai pangkalan data untuk menyimpan data, dan PHP berfungsi sebagai perantara yang mengawal pergerakan data di antara pangkalan data dan laman web. Secara keseluruhannya, pembangunan SmartAISystem dapat menyelesaikan masalah sedia ada, dan meningkatkan keupayaan serta kecekapan staf dalam membuat pembahagian kumpulan pelajar secara sistematik.

Volvariella volvacea, commonly referred to as paddy straw mushroom, is renowned for its remarkable medicinal and nutritional properties. This mushroom, part of the family Pluteaceae, thrives in tropical and subtropical regions and is highly esteemed for its distinctive flavor and substantial health benefits. The fruiting body of V. volvacea is a rich source of bioactive compounds, including antioxidant enzymes, terpenes, polypeptides, sugars, phenolics, and flavonoids. These compounds exhibit an extensive range of therapeutic activities such as anti-tumor, anti-microbial, antioxidant, anti-malarial, anti-cancer, anti-inflammatory, and anti-allergic effects. Nutritionally, V. volvacea is an excellent source of carbohydrates, proteins, fibers, ascorbic acid, and essential minerals. It also boasts a comprehensive profile of amino acids, including valine, arginine, glutamine, serine, aspartic acid, leucine, isoleucine, tyrosine, asparagine, lysine, cystine, proline, glycine, tryptophan, methionine, phenylalanine, threonine, and histidine. This review emphasizes the significant medicinal and nutritional potential of V. volvacea, advocating its inclusion as a functional food to enhance human health and well-being. By highlighting its diverse bioactive compounds and therapeutic benefits, this review aims to foster greater recognition and utilization of paddy straw mushroom in both dietary and medicinal applications.

In the Haber-Bosch process (HBp), which uses elevated pressure and temperature to produce more concentration of nitrogen and hydrogen gases, 90% of the 175 million metric tons of NH3 generated worldwide in 2016 were manufactured in this process. According to the road plan for sustainable ammonia production sustainably, using water as a reducing agent is the most effective way to fix nitrogen in close-quarters ambiance. A complete explanation of theoretical and practical work on electrocatalytic nitrogen reduction is provided in this article, with special attention paid to the low selectivity of nitrogen reduction to ammonia in comparison to protons to hydrogen. Since they are essential for accurately achieving high nitrogen production and Faradaic efficiency (FE), their information outlines electrocatalysts, electrolyte selection criteria, and managed experiment design. Under diverse conditions, the evolution of theory and experiment is examined. Finally, feedback is given on this field’s present issues and prospects.

AI has helped dental care professionals in different aspects which directly influence the increase in quality of service provided by dentists and improving patient personalized experience. AI can detect carious lesions, and gingival health, interpret X-rays and CBCT, record impressions of flabby tissues, and predict patient experience with accuracy and precision of more than 85%. AI-based robots can mimic patient expressions and reactions in dental treatment helping dental students at the undergraduate level. AI-based robotics can play an important role in different dental procedures because of the lack of tiredness as compared to manual instrumentation. Machine learning can play a vital role in detecting cancer markers, histological features of oral tissues, and forensic odontology. AI software used to interpret CBCT, and X-rays is useful to dental surgeons since it can measure bone height and width and help clinicians plan treatment accordingly. Patient data records are easily accessible to researchers and clinicians when data is digitalized with the help of AI software. AI has its limitations mainly because of ethical considerations, In the future dentists should make comprehensive AI-based clinics that would record patient pre-treatment records, medical history, and dental history and make treatment plans accordingly.

The crossbreed originated from male native chicken x female commercial layers, currently in Indonesia called a Super Native Chicken (Ayam Kampung Super). This study aimed to evaluate the ability of a selected local KUB (Ayam Kampung Unggul Balitbangtan) rooster to cross female ISA Brown chickens to produce Indonesian super native chickens. In comparison, the ISA hen was crossed with an unselected local chicken of bangkok descent (Ayam Kampung Turunan Bangkok, KTB) rooster, and the same hen strain was crossed with a Rhode Island Red (RIR) rooster. The treatment was crossbreeding (CB): CB1= KUB x ISA, CB2= KTB x ISA, and CB3= RIR x ISA. The results of the study showed that there were no significant (P>0.05) effects on fertility, hatchability, embryonic mortality, or chick abnormalities, but KUB x ISA resulted in significantly greater (P