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16 results on '"Mu, Xiaosong"'

1. The diversity of inhibitory receptor co-expression patterns of exhausted CD8+ T cells in oropharyngeal carcinoma

Author

Rao, Yufang, Qiu, Ke, Song, Yao, Mao, Minzi, Feng, Lan, Cheng, Danni, Li, Junhong, Zhang, Ziyan, Zhang, Yuyang, Shao, Xiuli, Pang, Wendu, Wang, Yan, Chen, Xuemei, Jiang, Chuanhuan, Wu, Sisi, Yu, Shuaishuai, Liu, Jun, Wang, Haiyang, Peng, Xingchen, Yang, Lin, Chen, Li, Mu, Xiaosong, Zheng, Yongbo, Xu, Wei, Liu, Geoffrey, Chen, Fei, Yu, Haopeng, Zhao, Yu, and Ren, Jianjun

Published
2024
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6. Comparison of Primary B/NKT Non‐Hodgkin Lymphomas in Nasopharynx, Nasal Cavity, and Paranasal Sinuses

Author

Peng, Jiajia, primary, Qiu, Jianqing, additional, Cheng, Danni, additional, Rao, Yufang, additional, Mao, Minzi, additional, Qiu, Ke, additional, Li, Junhong, additional, Chen, Fei, additional, Liu, Feng, additional, Liu, Jun, additional, Mu, Xiaosong, additional, Yu, Wenxin, additional, Zhang, Wei, additional, Xu, Wei, additional, Zhao, Yu, additional, and Ren, Jianjun, additional

Published
2023
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9. The Relationship Between Sleep Traits and Tinnitus in UK Biobank: A Population-Based Cohort Study

Author

Peng, Jiajia, primary, Dong, Yijun, additional, Luo, Yaxin, additional, Qiu, Ke, additional, Cheng, Danni, additional, Rao, Yufang, additional, Song, Yao, additional, Pang, Wendu, additional, Mu, Xiaosong, additional, Hu, Chunhong, additional, Chen, Hongchang, additional, Zhang, Wei, additional, Xu, Wei, additional, Ren, Jianjun, additional, and Zhao, Yu, additional

Published
2022
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11. Evaluating the prognostic contributions of TNM classifications and building novel staging schemes for middle ear squamous cell carcinoma

Author

Qiu, Ke, primary, Pang, Wendu, additional, Qiu, Jianqing, additional, Li, Junhong, additional, Cheng, Danni, additional, Rao, Yufang, additional, Dong, Yijun, additional, Mao, Minzi, additional, Liu, Qiurui, additional, Mu, Xiaosong, additional, Zhang, Wei, additional, Xu, Wei, additional, Ren, Jianjun, additional, and Zhao, Yu, additional

Published
2021
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12. miR-937 regulates the proliferation and apoptosis via targeting APAF1 in breast cancer

Author

Fang, Huiying, Jiang, Wei, Jing, Zhouhong, Mu, Xiaosong, and Xiong, Zhongxun

Subjects
miR-937, cell proliferation, breast cancer, APAF1, apoptosis, OncoTargets and Therapy, Original Research
Abstract

Huiying Fang, Wei Jiang, Zhouhong Jing, Xiaosong Mu, Zhongxun XiongDepartment of Breast Disease, Chongqing University Cancer Hospital, Chongqing City, 400000, People’s Republic of ChinaBackground: Previous research had shown that an imbalance in cell proliferation and apoptosis is a vital mechanism for tumorigenesis and cancer progression that may directly influence biological behaviors of cancer. microRNAs are associated with the occurrence and development of tumors. This study aimed to explore the influence of miR-937 on breast cancer regulation of APAF1 expression.Methods: Cancer Genome Altas microarray analysis (fold change > 2, p

Published
2019

16. Natural Antisense Long Noncoding RNA HHIP-AS1 Suppresses Non-Small-Cell Lung Cancer Progression by Increasing HHIP Stability via Interaction with CELF2.

Author

Yang Y, Cheng Y, Mou Y, Tang X, and Mu X

Subjects
Humans, Cell Movement genetics, Gene Expression Regulation, Neoplastic genetics, Cell Line, Tumor, Hedgehog Proteins genetics, Hedgehog Proteins metabolism, Cell Proliferation genetics, CELF Proteins genetics, CELF Proteins metabolism, Nerve Tissue Proteins genetics, Nerve Tissue Proteins metabolism, Carrier Proteins metabolism, Membrane Glycoproteins genetics, Membrane Glycoproteins metabolism, Carcinoma, Non-Small-Cell Lung genetics, Carcinoma, Non-Small-Cell Lung metabolism, RNA, Long Noncoding genetics, Lung Neoplasms genetics, Lung Neoplasms metabolism, MicroRNAs genetics
Abstract

Non-small-cell lung cancer (NSCLC) is a major category of lung cancer, with high incidence and high mortality. Natural antisense long noncoding RNAs (lncRNAs) are involved in the development of NSCLC via their regulation of biological processes. However, the function of the lncRNA Hedgehog-interacting protein antisense RNA 1 (HHIP-AS1) in NSCLC is mostly unknown. In the study discussed here, HHIP-AS1 and HHIP levels were predicted based on the TCGA database, and detected via qRT-PCR or western blotting assays. Cell proliferation, migration, and invasion were measured via CCK-8 and trans-well assays. Related protein levels were measured using western blotting analysis. The results showed that HHIP-AS1 and HHIP levels are downregulated in NSCLC, and that low HHIP-AS1 and HHIP expression is associated with poor outcomes. HHIP-AS1 overexpression represses cell proliferation, migration, and invasion in NSCLC. HHIP-AS1 enhances HHIP expression and stability, and this effect is mediated by CELF2. HHIP silencing attenuates the suppressive roles of HHIP-AS1 in proliferation, migration, and invasion. As a result of these findings, it is concluded that HHIP-AS1 overexpression restrains proliferation, migration, and invasion of NSCLC cells by increasing HHIP stability via its targeting of CELF2.

Published
2022
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