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35 results on '"Mu, Changjun"'

16. Exploring the biogeography, morphology, and phylogeny of the condylostomatid ciliates (Alveolata, Ciliophora, Heterotrichea), with establishment of four new Condylostomaspecies and a revision including redescriptions of five species found in China

Author

Chi, Yong, Wei, Fan, Tang, Danxu, Mu, Changjun, Ma, Honggang, Wang, Zhe, Al-Rasheid, Khaled A. S., Hines, Hunter N., and Chen, Xiangrui

Abstract

Species of the ciliate class Heterotrichea Stein, 1859 are a cosmopolitan group of unicellular eukaryotic microorganisms, many of which have been widely used as models in various fields of research such as regenerative biology, functional ecology, environmental toxicology, and symbiotic behavior. However, species identification in the heterotrich family Condylostomatidae, especially the most species-rich and type genus CondylostomaBory de Saint-Vincent, 1824, remains challenging due to incomplete original descriptions, few reliable distinguishing characters, and overlapping features between different species. This study presents an updated revision of Condylostomaand its related genus Condylostomidesda Silva Neto, 1994 based on descriptions of five species, including nine populations collected from China, using both morphological and molecular methods. The main findings are as follows: (1) 43 nominal species and about 130 populations are reviewed, resulting in the recognition of 30 valid species of Condylostomaand eight valid species of Condylostomides; (2) keys, synonyms, biogeographic distributions and amended/improved diagnoses of all valid species are provided; (3) based on the available data, four new Condylostomaspecies (C. marinumsp. nov., C. petzisp. nov., C. villeneuveisp. nov., and C. microstomumsp. nov.), one new combination (Condylostomides minimus(Dragesco, 1954) comb. nov. & nom. corr.), and two corrected names (Condylostoma ancestraleVilleneuve-Brachon, 1940 nom. corr. and Condylostomides nigrus(Dragesco, 1960) nom. corr.) are suggested; (4) cryptic species are detected and proposed for the first time to form the Condylostoma curvumspecies complex; (5) three highly confusing Condylostomaspecies, C. kris, C. spatiosum, and C. minutum, are redefined for the first time based on modern taxonomic methods; (6) a ‘flagship’ species, Condylostomides coeruleus, is recorded for the first time from the continent of Asia, substantially expanding its biogeography; (7) ciliature adjacent to the distal end of the paroral membrane within the family Condylostomatidae is uniformly defined as frontal membranelles and is classified into three patterns according to the arrangement of kinetosomes, which serve as important key features.

Published
2024
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20. Accurate prediction of pore size distribution in hemodialysis membranes based on gel permeation chromatography.

Author

Mu, Changjun and Zhang, Jiemin

Subjects
*PORE size distribution, *HOLLOW fibers, *SMALL molecules, *CHRONIC kidney failure, *HEMODIALYSIS, *GEL permeation chromatography
Abstract

Dialyzers play an important role in hemodialysis, a process used for the treatment of chronic kidney disease. The pore size distribution (PSD) is one of the key factors affecting the performance of the dialyzer. However, due to the inherent characteristics of the current method of testing PSD, the accuracy of the test results needs to be improved. We improved the dextran retention method by considering concentration polarization and backfiltration, and explored the experimental conditions to obtain a more accurate PSD. Moreover, the experimental data obtained via gel permeation chromatography were further processed to represent the relationship more intuitively between pore size and pore size probability density. The in vitro toxin removal of the dialyzers was used to further analyze the relationship between the PSD and dialyzer performance. The results showed that the increase in the pore size of the hollow fiber membrane had no obvious effect on the clearance of small molecule toxins. However, under certain conditions, a larger pore size increased the clearance of the dialyzers on medium molecules. More accurate PSD results can help manufacturers analyze the clearance performance of dialyzers. Consequently, specific dialyzers can be designed for different situations, resulting in more effective treatment of the patients. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Overexpression of Small Heat Shock Protein LimHSP16.45 inArabidopsis Enhances Tolerance to Abiotic Stresses.

Author

Mu, Changjun, Zhang, Shijia, Yu, Guanzhong, Chen, Ni, Li, Xiaofeng, and Liu, Heng

Subjects
*HEAT shock proteins, *GENE expression, *ARABIDOPSIS, *BIOCOMPATIBILITY, *BRASSICACEAE, *OXIDATIVE stress
Abstract

Small heat shock proteins (smHSPs) play important and extensive roles in plant defenses against abiotic stresses. We cloned a gene for a smHSP from the David Lily (Lilium davidii (E. H. Wilson) Raffill var. Willmottiae), which we named LimHSP16.45 based on its protein molecular weight. Its expression was induced by many kinds of abiotic stresses in both the lily and transgenic plants of Arabidopsis. Heterologous expression enhanced cell viability of the latter under high temperatures, high salt, and oxidative stress, and heat shock granules (HSGs) formed under heat or salinity treatment. Assays of enzymes showed that LimHSP16.45 overexpression was related to greater activity by superoxide dismutase and catalase in transgenic lines. Therefore, we conclude that heterologous expression can protect plants against abiotic stresses by preventing irreversible protein aggregation, and by scavenging cellular reactive oxygen species. [ABSTRACT FROM AUTHOR]

Published
2013
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