37 results on '"Mozaffari-Jovin, Sina"'
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2. PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects
3. Design Principles of a Novel Construct for HBB Gene-Editing and Investigation of Its Gene-Targeting Efficiency in HEK293 Cells
4. The effect of modification of DNA interference on myostatin gene expression in mice
5. An Update on the Application of CRISPR Technology in Clinical Practice
6. Recent Advances in CRISPR/Cas9 Delivery Approaches for Therapeutic Gene Editing of Stem Cells
7. Characterization of stability, safety and immunogenicity of the mRNA lipid nanoparticle vaccine Iribovax® against COVID-19 in nonhuman primates
8. An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines
9. Isolation of plasma small extracellular vesicles by an optimized size-exclusion chromatography-based method for clinical applications
10. Insights into the structural peculiarities of the N-terminal and receptor binding domains of the spike protein from the SARS-CoV-2 Omicron variant
11. TWIST1 activates cancer stem cell marker genes to promote epithelial-mesenchymal transition and tumorigenesis in esophageal squamous cell carcinoma
12. AI-driven covalent drug design strategies targeting main protease (m pro ) against SARS-CoV-2: structural insights and molecular mechanisms
13. The effect of modification of DNA interference on myostatin gene expression in mice
14. Guidelines for pre-analytical conditions for assessing the methylation of circulating cell-free DNA
15. Selective capture of plasma cell-free tumor DNA on magnetic beads: a sensitive and versatile tool for liquid biopsy
16. Light-Sheet Fluorescent Microscopy: Fundamentals, Developments and Applications
17. MERISTEM-DEFECTIVE regulates the balance between stemness and differentiation in the root meristem through RNA splicing control
18. Progressive accumulation of cytoplasmic aggregates in PRPF31 retinal pigment epithelium cells interferes with cell survival
19. MERISTEM-DEFECTIVE / DEFECTIVELY ORGANIZED TRIBUTARIES2 regulates the balance between stemness and differentiation in the root meristem through RNA splicing control
20. Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
21. Inhibition of RNA Helicase Brr2 by the C-Terminal Tail of the Spliceosomal Protein Prp8
22. Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient‐induced pluripotent stem cell‐derived retinal pigment epithelium cells
23. Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy
24. Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond
25. SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes
26. Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19.
27. SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes
28. Hydroxyapatite as a biomaterial – a gift that keeps on giving
29. Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors
30. Human iPSC-derived RPE and retinal organoids reveal impaired alternative splicing of genes involved in pre-mRNA splicing in PRPF31 autosomal dominant retinitis pigmentosa
31. The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation
32. A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing
33. Author response: A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing
34. The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome
35. Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans
36. The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA
37. A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.
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