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457 results on '"Moyna, Niall M."'

3. The impact of gas transfer on responses to exercise training in patients with pulmonary hypertension.

Author

McCormack, Ciara, Kehoe, Brona, McCullagh, Brian, Gaine, Sean, Moyna, Niall M., and Quadery, Syed Rehan

Subjects
EXERCISE therapy, PHYSICAL mobility, PULMONARY hypertension, PHYSICAL activity, LUNG volume measurements
Abstract

Exercise training is recommended for pulmonary hypertension (PH). Post hoc analysis of the PH and Home‐Based (PHAHB) trial stratified patients into two groups based on median diffusing capacity of the lungs for carbon monoxide (DLCO). Patients with higher DLCO had a greater improvement in physical activity performance in response to exercise training, compared to those with lower DLCO. DLCO may be an important consideration in prescribing exercise in PH. [ABSTRACT FROM AUTHOR]

Published
2024
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5. A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile

Author

Twomey, Laura, Navasiolava, Nastassia, Robin, Adrien, Bareille, Marie-Pierre, Gauquelin-Koch, Guillemette, Beck, Arnaud, Larcher, Françoise, Meade-Murphy, Gerardene, Sheridan, Sinead, Maguire, Patricia B., Harrison, Michael, Degryse, Bernard, Moyna, Niall M., Gharib, Claude, Custaud, Marc-Antoine, and Murphy, Ronan P.

Published
2021
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8. A polymorphism near IGF1 is associated with body composition and muscle function in women from the Health, Aging, and Body Composition Study

Author

Kostek, Matthew C., Devaney, Joseph M., Gordish-Dressman, Heather, Harris, Tamara B., Thompson, Paul D., Clarkson, Priscilla M., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Seip, Richard L., Garcia, Melissa, Li, Rongling, Zmuda, Joseph M., Delmonico, Matthew J., Kanaya, Alka, and Hoffman, Eric P.

Subjects
Biomedicine, Sports Medicine, Occupational Medicine/Industrial Medicine, Human Physiology, IGF1, Muscle, Body composition, Bone mineral density, Elderly, SNP
Abstract

Previous studies have reported associations of polymorphisms in the IGF1 gene with phenotypes of body composition (BC). The purpose of this study was to identify phenotypes of BC and physical function that were associated with the IGF1 promoter polymorphism (rs35767, −C1245T). Subjects from the Health, Aging, and Body Composition Study, white males and females (n = 925/836) and black males and females (533/705) aged 70–79 years were genotyped for the polymorphism. Phenotypes of muscle size and function, bone mineral density, and BC were analyzed for associations with this polymorphism. To validate and compare these findings, a cohort of young (mean age = 24.6, SD = 5.9) white men and women (n = 173/296) with similar phenotypic measurements were genotyped. An association with BC was identified in elderly females when significant covariates (physical activity, age, smoking status, body mass index) were included. White women with C/C genotype had 3% more trunk fat and 2% more total fat than those with C/T (P

Published
2010

31. Activity profile of elite Gaelic football referees during competitive match play.

Author

Brady, Aidan J., Moyna, Niall M., Scriney, Michael, and McCarren, Andrew

Subjects
GAELIC football referees, RUNNING speed, GLOBAL Positioning System
Abstract

The purpose of this study was to examine the activity profile of elite Gaelic football referees (GFR) and to examine temporal changes between the first and second half and across the four quarters. Global positioning systems technology (10-Hz) was used to collect activity data during 202 competitive games from 23 elite GFR. Relative distance, peak running speed and relative distance covered in six movement categories [very low-speed movement (VLSM) (<0.70 m·s−1), walking (≥0.70–1.65 m·s−1), low-speed running (LSR) (≥1.66–3.27 m·s−1), moderate-speed running (MSR) (≥3.28–4.86 m·s−1), high-speed running (HSR) (≥4.87–6.48 m·s−1), very high-speed running (VHSR) (≥6.49 m·s−1)] were examined during the full game, first and second half, and across the four quarters. The relative distance covered was 122.6 ± 8.4 m·min−1, with 13.1 ± 4.9 m·min−1 of HSR and VHSR. The peak running speed was 6.75 ± 0.49 m·s−1. The relative (ES=0.60), MSR (ES=0.50) and HSR (ES=0.14) distance was higher in the first half than the second half. A higher relative (ES=0.62–0.91) and HSR (ES=0.51–0.61) distance was found in the first quarter than any other period. No differences in HSR distance were found between the second, third and fourth quarters (ES=0.04–0.10). This study provides, for the first time, a detailed insight into the activity profile of elite GFR during competitive games and demonstrates the demanding, intermittent nature of elite refereeing in Gaelic football. This information may be used as a framework for coaches to design training programmes specific to GFR. [ABSTRACT FROM AUTHOR]

Published
2023
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36. AKT1 polymorphisms are associated with risk for metabolic syndrome

Author

Devaney, Joseph M., Gordish-Dressman, Heather, Harmon, Brennan T., Bradbury, Margaret K., Devaney, Stephanie A., Harris, Tamara B., Thompson, Paul D., Clarkson, Priscilla M., Price, Thomas B., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Seip, Richard L., Seo, Jinwook, Kim, Bo Hyoung, Tosi, Laura L., Garcia, Melissa, Li, Rongling, Zmuda, Joseph M., Delmonico, Matthew J., Lindsay, Robert S., Howard, Barbara V., Kraus, William E., and Hoffman, Eric P.

Published
2011
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39. SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength

Author

Sprouse, Courtney, Gordish-Dressman, Heather, Orkunoglu-Suer, E. Funda, Lipof, Jason S., Moeckel-Cole, Stephanie, Patel, Ronak R., Adham, Kasra, Larkin, Justin S., Hubal, Monica J., Kearns, Amy K., Clarkson, Priscilla M., Thompson, Paul D., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Hoffman, Eric P., Tosi, Laura L., and Devaney, Joseph M.

Subjects
Muscle strength -- Physiological aspects -- Health aspects -- Genetic aspects, Medical genetics -- Research, Isometric exercise -- Physiological aspects -- Health aspects -- Genetic aspects, Single nucleotide polymorphisms -- Health aspects, Type 2 diabetes -- Genetic aspects -- Risk factors, Allelomorphism -- Health aspects, Muscles -- Physiological aspects -- Health aspects -- Genetic aspects, Health
Abstract

Genome-wide association studies have identified thousands of variants that are associated with numerous phenotypes. One such variant, rs13266634, a nonsynonymous single nucleotide polymorphism in the solute carrier family 30 (zinc transporter) member eight gene, is associated with a 53% increase in the risk of developing type 2 diabetes (T2D). We hypothesized that individuals with the protective allele against T2D would show a positive response to short-term and long-term resistance exercise. Two cohorts of young adults--the Eccentric Muscle Damage (EMD; n = 156) cohort and the Functional Single Nucleotide Polymorphisms Associated with Muscle Size and Strength Study (FAMuSS; n = 874)--were tested for association of the rs13266634 variant with measures of skeletal muscle response to resistance exercise. Our results were sexually dimorphic in both cohorts. Men in the EMD study with two copies of the protective allele showed less post-exercise bout strength loss, less soreness, and lower creatine kinase values. In addition, men in the FAMuSS, homozygous for the protective allele, showed higher pre-exercise strength and larger arm skeletal muscle volume, but did not show a significant difference in skeletal muscle hypertrophy or strength with resistance training. Diabetes 2014;63:363-368 | DOI: 10.2337/db13-1150, Genome-wide association studies (GWASs) are extensively used as a tool to discover common single nucleotide polymorphisms (SNPs) associated with complex disease phenotypes such as type 2 diabetes (T2D), dyslipidemia, and [...]

Published
2014
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40. Response to Comment on Sprouse et al. SLC30A8 Nonsynonymous Variant Is Associated With Recovery Following Exercise and Skeletal Muscle Size and Strength. Diabetes 2014;63: 363–368

Author

Sprouse, Courtney, Gordish-Dressman, Heather, Orkunoglu-Suer, E. Funda, Lipof, Jason S., Moeckel-Cole, Stephanie, Patel, Ronak R., Adham, Kasra, Larkin, Justin S., Hubal, Monica J., Kearns, Amy K., Clarkson, Priscilla M., Thompson, Paul D., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Hoffman, Eric P., Tosi, Laura L., and Devaney, Joseph M.

Published
2014
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46. Feasibility, acceptability, and clinical effectiveness of a technology-enabled cardiac rehabilitation platform (Physical Activity Toward Health-I): randomized controlled trial

Author

ERC, Claes, Jomme, Cornelissen, Veronique A., McDermott, Clare, Moyna, Niall M., Pattyn, Nele, Cornelis, Nils, Gallagher, Anne, McCormack, Ciara, Newton, Helen, Gillain, Alexandra, Budts, Werner, Goetschalckx, Kaatje, Woods, Catherine B., Moran, Kieran A., Buys, Roselien, ERC, Claes, Jomme, Cornelissen, Veronique A., McDermott, Clare, Moyna, Niall M., Pattyn, Nele, Cornelis, Nils, Gallagher, Anne, McCormack, Ciara, Newton, Helen, Gillain, Alexandra, Budts, Werner, Goetschalckx, Kaatje, Woods, Catherine B., Moran, Kieran A., and Buys, Roselien

Abstract

peer-reviewed, BACKGROUND: Cardiac rehabilitation (CR) is highly effective as secondary prevention for cardiovascular diseases (CVDs). Uptake of CR remains suboptimal (30% of eligible patients), and long-term adherence to a physically active lifestyle is even lower. Innovative strategies are needed to counteract this phenomenon. OBJECTIVE: The Physical Activity Toward Health (PATHway) system was developed to provide a comprehensive, remotely monitored, home-based CR program for CVD patients. The PATHway-I study aimed to investigate its feasibility and clinical efficacy during phase III CR. METHODS: Participants were randomized on a 1:1 basis to the PATHway (PW) intervention group or usual care (UC) control group in a single-blind, multicenter, randomized controlled pilot trial. Outcomes were assessed at completion of phase II CR and 6-month follow-up. The primary outcome was physical activity (PA; Actigraph GT9X link). Secondary outcomes included measures of physical fitness, modifiable cardiovascular risk factors, endothelial function, intima-media thickness of the common carotid artery, and quality of life. System usability and patients' experiences were evaluated only in PW. A mixed-model analysis of variance with Bonferroni adjustment was used to analyze between-group effects over time. Missing values were handled by means of an intention-to-treat analysis. Statistical significance was set at a 2-sided alpha level of .05. Data are reported as mean (SD). RESULTS: A convenience sample of 120 CVD patients (mean 61.4 years, SD 13.5 years; 22 women) was included. The PATHway system was deployed in the homes of 60 participants. System use decreased over time and system usability was average with a score of 65.7 (SD 19.7; range 5-100). Moderate-to-vigorous intensity PA increased in PW (PW: 127 [SD 58] min to 141 [SD 69] min, UC: 146 [SD 66] min to 143 [SD 71] min; Pinteraction=.04; effect size of 0.42), while diastolic blood pressure (PW: 79 [SD 11] mmHg to 79 [SD 10] mmHg, UC: 78 [S, PUBLISHED, peer-reviewed

Published
2020

47. Effect of a defined lacto-ovo-vegetarian diet and oral creatine monohydrate supplementation on plasma creatine concentration

Author

Lukaszuk, Judith M., Robertson, Robert J., Arch, Judith E., and Moyna, Niall M.

Subjects
Creatine -- Usage, Creatine -- Physiological aspects, Adenosine triphosphate -- Physiological aspects, Health, Sports and fitness
Abstract

This study examined the effects that preceding creatine supplementation with a lacto-ovo-vegetarian diet would have on plasma creatine concentration. Twenty-six healthy moderately fit omnivorous men were assigned to either a 26-day lacto-ovo-vegetarian (LOV; n = 12) or omnivorous (Omni; n = 14) diet. On day 22, subjects were also assigned in a double-blind manner either creatine monohydrate (CM; 0.3 g*[kg.sup.-1]*[day.sup.-1] + 20 g Polycose) or an equivalent dose of placebo (PL) for 5 days. Blood samples were taken on days 1, 22 and 27. Consuming a LOV diet for 21 days was effective in reducing plasma creatine concentration (p < 0.01) in the LOV group. Regardless of diet, the CM group showed an increase in plasma creatine concentrations from day 22 to 27, whereas the PL group's levels remained the same (p < 0.05). Although the LOV diet caused a deprivation effect in plasma creatine concentration relative to the Omni diet, concurrent supplementation with creatine resulted in no difference in plasma creatine concentrations between the LOV and Omni diet groups. Dietary advice should be provided to LOV athletes that supplementation with creatine may help to increase their muscle stores of creatine, and thus their ATP resynthesis capabilities, to levels similar to those of omnivores. Key Words. omnivorous diet, creatine free diet, blood creatine level

Published
2005

49. Postexercise hypotension differs between white and black women

Author

Pescatello, Linda S., Bairos, Lynn, VanHeest, Jaci L., Maresh, C. M., Rodriguez, N. R., Moyna, Niall M., DiPasquale, Christopher, Collins, Valerie, Meckes, Cherie L., Krueger, Lori, and Thompson, Paul D.

Subjects
Blood pressure -- Influence, Cookery for hypertensives -- Research, Cookery for hypertensives -- Influence, Hypertension -- Research, Hypertension -- Influence, Postmenopausal women -- Influence, Postmenopausal women -- Health aspects, Exercise -- Influence, Health
Published
2003

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