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* Objective. - Acute mountain sickness has been described in adults but little is known concerning its occurrence in children. Our objective was to determine the incidence of acute mountain sickness in children. Methods. - A survey questionnaire was completed by 558 children (aged 9 to 14 years) after they ascended from 1600 to 2835 m and from 405 similarly aged children after travel at sea level. Results. - Three or more of the following symptoms in the high-altitude setting were considered as the case definition of acute mountain sickness: headache, loss of appetite, vomiting, fatigue, insomnia, shortness of breath, and dizziness. One hundred fifty-six (28%) of the children at 2835 m developed acute mountain sickness. Three or more symptoms developed in a smaller, but nonetheless considerable, number (86 [21%]) of children at sea level. Headache, shortness of breath, and dizziness were reported more frequently at high altitude than at low altitude, whereas the other symptoms occurred with equal frequency at the two locations. Conclusions. - More than one fourth of the children visiting high altitude developed acute mountain sickness. A high proportion (21 %) of children at sea level developed similar symptoms, suggesting that an appreciable portion of the symptoms present were due to factors other than altitude, such as travel, anxiety, or disruption of daily routine., More than a fourth of the children attending a science camp in Colorado at an elevation of 2,835 meters (m) developed acute mountain sickness (AMS). AMS is characterized by headache, loss of appetite, vomiting, fatigue, shortness of breath and dizziness. Although it is common among adults who visit high altitudes, little is known about its incidence among children. Of 963 children between the ages of nine and 14, 405 attended a camp at an altitude of 30 m, and 558 attended a camp at 2,835 m. At least one symptom of AMS was reported by 74% of the children who attended the high altitude camp and by 67% of the children who attended the low altitude camp. Among children at the high altitude camp, 28% developed AMS. However, 21% of the children at the low altitude camp also developed AMS, which suggests that some of the symptoms may have resulted from other factors such as travel, anxiety or disruption of normal routines.