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1. Associações Entre Defeitos de Perfusão, Características Tecidulares e Deformação Miocárdica na Miocardiopatia Hipertrófica, uma Análise Segmentar por Ressonância Magnética Cardíaca

Author

Brás, P, Aguiar Rosa, S, Thomas, B, Fiarresga, A, Cardoso, I, Pereira, R, Branco, G, Cruz, I, Baquero, L, Cruz Ferreira, R, Mota Carmo, M, and Rocha Lopes, L

Subjects
Strain Imaging, Myocardial Deformation, Coronary Microvascular Dysfunction, Hypertrophic Cardiomyopathy, Cardiac Magnetic Resonance, HSM CAR, Cardiology and Cardiovascular Medicine, Tissue Characteristics
Abstract

Background: Microvascular dysfunction is an often overlooked feature of hypertrophic cardiomyopathy (HCM). Our aim was to assess the association between microvascular dysfunction, wall thickness, tissue characteristics and myocardial deformation in HCM patients, by analyzing individual myocardial segments. Methods: Prospective assessment including cardiac magnetic resonance to assess wall thickness, T1 and T2 mapping, extracellular volume, late gadolinium enhancement (LGE) and stress perfusion. Results were stratified according to the 16 American Heart Association segments. Results: Seventy-five patients were recruited (1200 segments), 63% male, mean age 54.6±14.8 years, maximal wall thickness of 20.22±4.6 mm. Among the 424 segments (35%) with perfusion defects, 24% had defects only in the endocardial layer and 12% in both endocardial and epicardial layers. Perfusion defects were more often detected in hypertrophied segments (64%). Among the 660 segments with normal wall thickness, 19% presented perfusion defects. Independently of wall thickness, segments with perfusion defects had a higher T1 (β-estimate 30.28, p

Published
2022

2. Microvascular dysfunction is associated with impaired myocardial work in obstructive and nonobstructive hypertrophic cardiomyopathy: a multimodality approach

Author

Garcia Bras, P, primary, Cardoso, I, additional, Aguiar Rosa, S, additional, Moura Branco, L, additional, Galrinho, A, additional, Valentim Goncalves, A, additional, Thomas, B, additional, Fiarresga, A, additional, Mota Carmo, M, additional, Branco, G, additional, Pereira, R, additional, Selas, M, additional, Silva, F, additional, Rocha Lopes, L, additional, and Cruz Ferreira, R, additional

Published
2022
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7. Proinflammatory Soluble CD40 Ligand Is Associated with the Systemic Extent of Stable Atherosclerosis

Author

Pereira da Silva, T, Napoleão, P, Pinheiro, T, Selas, M, Silva, F, Cruz Ferreira, R, and Mota Carmo, M

Subjects
Inflammation, CD40 Ligand, Humans, Coronary Artery Disease, HSM CAR, Atherosclerosis
Abstract

Background and objectives: Polyvascular atherosclerosis is frequent and associated with a high cardiovascular risk, although the mechanisms regulating the atherosclerosis extent to single or multiple arterial territories are still poorly understood. Inflammation regulates atherogenesis and soluble CD40 ligand (sCD40L) is an inflammatory mediator associated with the presence of single-territorial atherosclerosis. We assessed whether the sCD40L expression is associated with the atherosclerosis extent to single or multiple arterial territories and with the atherosclerosis severity in different territories. Materials and Methods: We prospectively enrolled 94 participants with no atherosclerosis (controls, n = 26); isolated coronary atherosclerosis (group 1, n = 20); coronary and lower extremity (LE) atherosclerosis (group 2, n = 18); coronary and carotid atherosclerosis (group 3, n = 12); and coronary, LE, and carotid atherosclerosis (group 4, n = 18). Serum sCD40L levels were quantified. Results: The sCD40L levels (ng/mL, mean (standard deviation)) were 4.0 (1.5), 5.6 (2.6), 7.2 (4.2), 5.9 (3.7), and 5.1 (2.4) in controls and groups 1 to 4, respectively (ANOVA p = 0.012). In nonrevascularized patients, the sCD40L levels were significantly higher in group 2 than in group 1 and were correlated with the number of LE diseased segments. Prior LE bypass surgery was associated with lower sCD40L levels. Coexistence of coronary and LE atherosclerosis was independently associated with the sCD40L levels. Conclusions: The sCD40L levels were increased in stable atherosclerosis, particularly in polyvascular coronary and LE atherosclerosis. The number of LE diseased segments and prior LE revascularization were associated with sCD40L expression. To our knowledge, these are novel data, which provide insights into the mechanisms underlying multi-territorial atherosclerosis expression. sCD40L may be a promising noninvasive tool for refining the stratification of the systemic atherosclerotic burden. info:eu-repo/semantics/publishedVersion

Published
2021

9. Association between microvascular dysfunction and impaired myocardial deformation in hypertrophic cardiomyopathy

Author

Aguiar Rosa, S, primary, Branco, L, additional, Thomas, B, additional, Fiarresga, A, additional, Lopes, L, additional, Galrinho, A, additional, Selas, M, additional, Silva, F, additional, Branco, G, additional, Pereira, R, additional, Barao, A, additional, Baquero, L, additional, Mota Carmo, M, additional, and Cruz Ferreira, R, additional

Published
2021
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11. Poster session: Aortic stenosis

Author

Carvalho, M S, De Araujo Goncalves, P, Sousa, P, Dores, H, Marques, H, Pereira Machado, F, Gaspar, A, Aleixo, A, Mota Carmo, M, and Roquette, J

Published
2012

16. 1185 Three-dimensional speckle tracking echocardiography for the global and regional assessment of myocardial deformation in breast cancer patients submitted to anthracyclines

Author

Coutinho Cruz, M, primary, Moura-Branco, L, additional, Portugal, G, additional, Galrinho, A, additional, Mota-Carmo, M, additional, Timoteo, A T, additional, Abreu, J, additional, Rio, P, additional, Ilhao-Moreira, R, additional, Mendonca, T, additional, Goncalves, A, additional, Mano, T, additional, Oliveira, S, additional, Luz, R, additional, and Cruz-Ferreira, R, additional

Published
2020
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18. Circulating MicroRNA Profiles in Different Arterial Territories of Stable Atherosclerotic Disease: a Systematic Review

Author

Tiago Pereira-da-Silva, Coutinho Cruz M, Carrusca C, Cruz Ferreira R, Napoleão P, and Mota Carmo M

Subjects
Disease Location, Circulating, MicroRNA, Review Article, HSM CAR, Atherosclerosis
Abstract

AIMS: Atherosclerosis is associated with altered circulating microRNA profiles. It is yet unclear whether the expression of these potential biomarkers differs according to the location of atherosclerosis. We assessed whether atherosclerosis of different arterial territories, except the coronary, is associated with specific circulating microRNA profiles. METHODS: A systematic search in PubMed, Web of Science, Embase, and Cochrane Library was carried out using a retrieval strategy including MESH and non-MSH terms. Eligible studies have compared circulating microRNA profiles between individuals with and without stable atherosclerotic disease of large or medium size arteries. The review protocol was registered in PROSPERO database (reference CRD42017073846). RESULTS: Eighteen studies were selected for qualitative synthesis: ten focused on carotid, six on lower limbs, and two on renal arteries atherosclerosis, none reporting on other locations. A common microRNA profile to different atherosclerotic disease locations was identified, including deregulation of miR-21, miR-30, miR-126, and miR-221-3p. Specific microRNA profiles for each territory were also identified, with consistency across studies, such as deregulation of miR-21 and miR-29 in carotid atherosclerosis, and let 7e, miR-27b, miR-130a, and miR-210 in lower limbs atherosclerosis. The robustness of the results was very high for let 7e, miR-29, miR-30, considering both the adjustment of microRNA expression for baseline variables and the replication of results in different studies (miR-29 in carotid, let 7e in lower limbs, and miR-30 in carotid and lower limbs atherosclerosis). Globally, the deregulated microRNAs are associated with control of angiogenesis, endothelial cell function, inflammation, cholesterol metabolism, oxidative stress and extracellular matrix composition. CONCLUSIONS: A common microRNA profile to different atherosclerotic disease locations and specific microRNA profiles for each territory were identified. These findings may provide insights into pathophysiology and be useful for selecting potential biomarkers for clinical practice. To the best of our knowledge, no systematic data on this subject has been reported. info:eu-repo/semantics/publishedVersion

Published
2018

20. 250Risk stratification of heart failure patients submitted to cardiac resynchronization therapy using a combination of renal function and 123I-mIBG scintigraphy

Author

Ilhao Moreira, R, primary, Abreu, A, additional, Oliveira, L, additional, Oliveira, M, additional, Rodrigues, I, additional, Coutinho Cruz, M, additional, Portugal, G, additional, Mano, T, additional, Silva Cunha, P, additional, Santos, V, additional, Santa Clara, H, additional, Mota Carmo, M, additional, and Cruz Ferreira, R, additional

Published
2019
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21. P1117The role of MIBG scintigraphy in anticipating the occurrence of sustained ventricular arrhythmias after CRT in patients with remote monitoring

Author

Coutinho Cruz, M., primary, Abreu, A., additional, Oliveira, M., additional, Delgado, A.S., additional, Santa Clara, H., additional, Santos, V., additional, Portugal, G., additional, Rodrigues, I., additional, Almeida Morais, L., additional, Ilhao Moreira, R., additional, Modas Daniel, P., additional, Mendonca, T., additional, Mota Carmo, M., additional, and Cruz Ferreira, R., additional

Published
2017
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22. 4774Cardiac sympathetic activity pre and post resynchronization therapy

Author

Ilhao Moreira, R., primary, Abreu, A., additional, Rodrigues, I., additional, Coutinho Cruz, M., additional, Portugal, G., additional, Mendonca, T., additional, Goncalves, A., additional, Santa Clara, H., additional, Oliveira, L., additional, Cunha, P., additional, Mota Carmo, M., additional, Oliveira, M., additional, and Cruz Ferreira, R., additional

Published
2017
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24. P4344Can we predict adverse events in patients with heart failure with reduced ejection fraction submitted to cardiac resynchronization therapy? The role of MIBG scintigraphy

Author

Coutinho Cruz, M., primary, Abreu, A., additional, Oliveira, M., additional, Santa Clara, H., additional, Santos, V., additional, Portugal, G., additional, Rodrigues, I., additional, Almeida Morais, L., additional, Ilhao Moreira, R., additional, Modas Daniel, P., additional, Aguiar Rosa, S., additional, Goncalves, A., additional, Mota Carmo, M., additional, and Cruz Ferreira, R., additional

Published
2017
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25. Limiar do Índice Homeostasis Model Assessment (HOMA) para Resistência à Insulina numa População de Doentes Admitidos Electivamente numa Enfermaria Portuguesa de Cardiologia

Author

Timóteo, AT, Miranda, F, Mota Carmo, M, and Cruz Ferreira, R

Subjects
HSM PAT CLIN, HSM MED, Homeostasis, Glucose Tolerance Test, Insulin Resistance Metabolic Syndrome
Abstract

INTRODUCTION: Insulin resistance is the pathophysiological key to explain metabolic syndrome. Although clearly useful, the Homeostasis Model Assessment index (an insulin resistance measurement) hasn't been systematically applied in clinical practice. One of the main reasons is the discrepancy in cut-off values reported in different populations. We sought to evaluate in a Portuguese population the ideal cut-off for Homeostasis Model Assessment index and assess its relationship with metabolic syndrome. MATERIAL AND METHODS: We selected a cohort of individuals admitted electively in a Cardiology ward with a BMI < 25 Kg/m2 and no abnormalities in glucose metabolism (fasting plasma glucose < 100 mg/dL and no diabetes). The 90th percentile of the Homeostasis Model Assessment index distribution was used to obtain the ideal cut-off for insulin resistance. We also selected a validation cohort of 300 individuals (no exclusion criteria applied). RESULTS: From 7 000 individuals, and after the exclusion criteria, there were left 1 784 individuals. The 90th percentile for Homeostasis Model Assessment index was 2.33. In the validation cohort, applying that cut-off, we have 49.3% of individuals with insulin resistance. However, only 69.9% of the metabolic syndrome patients had insulin resistance according to that cut-off. By ROC curve analysis, the ideal cut-off for metabolic syndrome is 2.41. Homeostasis Model Assessment index correlated with BMI (r = 0.371, p < 0.001) and is an independent predictor of the presence of metabolic syndrome (OR 19.4, 95% CI 6.6 - 57.2, p < 0.001). DISCUSSION: Our study showed that in a Portuguese population of patients admitted electively in a Cardiology ward, 2.33 is the Homeostasis Model Assessment index cut-off for insulin resistance and 2.41 for metabolic syndrome. CONCLUSION: Homeostasis Model Assessment index is directly correlated with BMI and is an independent predictor of metabolic syndrome.

Published
2014

26. Poster session 2THE IMAGING EXAMINATIONP536Appropriate use criteria of transthoracic echocardiography and its clinical impact: a continuous challengeP537Implementation of proprietary plug-ins in the DICOM-based computerized echo reporting system fuels the use of 3D echo and deformation imaging in the clinical routine of a multivendor laboratoryP538Exercise stress echocardiography appropriate use criteria: real-life cases classification ease and agreement among cardiologistsANATOMY AND PHYSIOLOGY OF THE HEART AND GREAT VESSELSP539Functional capacity in older people with normal ejection fraction correlates with left ventricular functional reserve and carotid-femoral pulse wave velocity but not with E/e and augmentation indexP540Survey of competency of practitioners for diagnosis of acute cardiopulmonary diseases manifest on chest x-rayASSESSMENT OF DIAMETERS, VOLUMES AND MASSP541Left atrium remodeling in dialysis patients with normal ejection fractionP542The prediction of postinfarction left ventricular remodeling and the role of of leptin and MCP-1 in regard to the presence of metabolic syndromeP543Ascending aorta and common carotid artery: diameters and stiffness in a group of 584 healthy subjectsAssessments of haemodynamicsP544Alternate echo parameters in patients without estimable RVSPAssessment of systolic functionP545Reduced contractile performance in heart failure with preserved ejection fraction: determination using novel preload-adjusted maximal left ventricular ejection forceP546Left ventricular dimensions and prognosis in acute coronary syndromesP547Time course of myocardial alterations in a murine model of high fat diet: A strain rate imaging studyP548Subclinical left ventricular systolic dysfunction in patients with premature ventricular contractionsP549Global myocardial strain by CMR-based feature tracking (FT) and tagging to predict development of severe left ventricular systolic dysfunction after acute st-elevation myocardial infarctionP550Echocardiographic analysis of left and right ventricular function in patients after mitral valve reconstructionP551The role of regional longitudinal strain assessment in predicting response to cardiac resynchronization therapy in patients with left ventricular systolic dysfunction and left bundle branch blockP552Speckle tracking automatic border detection improves echocardiographic evaluation of right ventricular systolic function in repaired tetralogy of fallot patients: comparison with MRI findingsP553Echocardiography: a reproducible and relevant tool in pah? intermediate results of the multicentric efort echogardiographic substudy (evaluation of prognostic factors and therapeutic targets in pah)Assessment of diastolic functionP554Relationship between left ventricular filling pressures and myocardial fibrosis in patients with uncomplicated arterial hypertensionP555Cardiac rehabilitation improves echocardiographic parameters of diastolic function in patients with ischemic heart diseaseP556Diastolic parameters in the calcified mitral annulusP557Biomarkers and echocardiography - combined weapon to diagnose and prognose heart failure with and without preserved ejection fractionP558Diastolic function changes of the maternal heart in twin and singleton pregnancyIschemic heart diseaseP559Syntax score as predictor for the correlation between epicardial adipose tissue and the severity of coronary lesions in patients with significant coronary diseaseP560Impact of strain analysis in ergonovine stress echocardiography for diagnosis vasospastic anginaP561Cardiac magnetic resonance tissue tracking: a novel method to predict infarct transmurality in acute myocardial infarctionP562Infarct size is correlated to global longitudinal strain but not left ventricular ejection fraction in the early stage of acute myocardial infarctionP563Magnetic resonance myocardial deformation assessment with tissue tracking and risk stratification in acute myocardial infarction patientsP564Increase in regional end-diastolic wall thickness by transthoracic echocardiography as a biomarker of successful reperfusion in anterior ST elevation acute myocardial infarctionP565Mitral regurgitation is associated with worse long-term prognosis in ST-segment elevation myocardial infarction treated with primary percutaneous coronary interventionP566Statistical significance of 3D motion and deformation indexes for the analysis of LAD infarctionHeart valve DiseasesP567Paradoxical low gradient aortic stenosis: echocardiographic progression from moderate to severe diseaseP568The beneficial effects of TAVI in mitral insufficiencyP569Impact of thoracic aortic calcification on the left ventricular hypertrophy and its regression after aortic valve replacement in patients with severe aortic stenosisP570Additional value of exercise-stress echocardiography in asymptomatic patients with aortic valve stenosisP571Valvulo-arterial impedance in severe aortic stenosis: a dual imaging modalities studyP572Left ventricular mechanics: novel tools to evaluate left ventricular performance in patients with aortic stenosisP573Comparison of long-term outcome after percutaneous mitral valvuloplasty versus mitral valve replacement in moderate to severe mitral stenosis with left ventricular dysfunctionP574Incidence of de novo left ventricular dysfunction in patient treated with aortic valve replacement for severe aortic regurgitationP575Transforming growth factor-beta dependant progression of the mitral valve prolapseP576Quantification of mitral regurgitation with multiple jets: in vitro validation of three-dimensional PISA techniqueP577Impaired pre-systolic contraction and saddle-shape deepening of mitral annulus contributes to atrial functional regurgitation: a three-dimensional echocardiographic studyP578Incidence and determinants of left ventricular (lv) reverse remodeling after MitraClip implantation in patients with moderate-to severe or severe mitral regurgitation and reduced lv ejection fractionP579Severe functional tricuspid regurgitation in rheumatic heart valve disease. New insights from 3D transthoracic echocardiographyP58015 years of evolution of the etiologic profile for prosthetic heart valve replacement through an echocardiography laboratoryP581The role of echocardiography in the differential diagnosis of prolonged fever of unknown originP582Predictive value for paravalvular regurgitation of 3-dimensional anatomic aortic annulus shape assessed by multidetector computed tomography post-transcatheter aortic valve replacementP583The significance and advantages of echo and CT imaging & measurement at transcatherter aortic valve implantation through the left common carotid accessP584Comparison of the self-expandable Medtronic CoreValve versus the balloon-expandable Edwards SAPIEN bioprostheses in high-risk patients undergoing transfemoral aortic valve implantationP585The impact of transcatheter aortic valve implantation on mitral regurgitation severityP586Echocardiographic follow up of children with valvular lesions secondary to rheumatic heart disease: Data from a prospective registryP587Valvular heart disease and different circadian blood pressure profilesCardiomyopathiesP588Comparison of transthoracic echocardiography versus cardiac magnetic for implantable cardioverter defibrillator therapy in primary prevention strategy dilated cardiomyopathy patientsP589Incidence and prognostic significance of left ventricle reverse remodeling in a cohort of patients with idiopathic dilated cardiomyopathyP590Early evaluation of diastolic function in fabry diseaseP591Echocardiographic predictors of atrial fibrillation development in hypertrophic cardiomyopathyP592Altered Torsion mechanics in patients with hypertrophic cardiomyopathy: LVOT-obstruction is the topdog?P593Prevention of sudden cardiac death in hypertrophic cardiomyopathy: what has changed in the guidelines?P594Coronary microcirculatory function as determinator of longitudinal systolic left ventricular function in hypertrophic cardiomyopathyP595Detection of subclinical myocardial dysfunction by tissue Doppler ehocardiography in patients with muscular dystrophiesP596Speckle tracking myocardial deformation analysis and three dimensional echocardiography for early detection of chemotherapy induced cardiac dysfunction in bone marrow transplantation patientsP597Left ventricular non compaction or hypertrabeculation: distinguishing between physiology and pathology in top-level athletesP598Role of multi modality imaging in familiar screening of Danon diseaseP599Early impairment of global longitudinal left ventricular systolic function independently predicts incident atrial fibrillation in type 2 diabetes mellitusP600Fetal cardiovascular programming in maternal diabetes mellitus and obesity: insights from deformation imagingP601Longitudinal strain stress echo evaluation of aged marginal donor hearts: feasibility in the Adonhers project.P602Echocardiographic evaluation of left ventricular size and function following heart transplantation - Gender mattersSystemic diseases and other conditionsP603The impact of septal kinetics on adverse ventricular-ventricular interactions in pulmonary stenosis and pulmonary arterial hypertensionP604Improvement in right ventricular mechanics after inhalation of iloprost in pulmonary hypertensionP605Does the treatment of patients with metabolic syndrome correct the right ventricular diastolic dysfunction?P606Predictors of altered cardiac function in breast cancer survivors who were treated with anthracycline-based therapyP607Prevalence and factors related to left ventricular systolic dysfunction in asymptomatic patients with rheumatoid arthritis: a prospective tissue-doppler echocardiography studyP608Diastolic and systolic left ventricle dysfunction presenting different prognostic implications in cardiac amyloidosisP609Diagnostic accuracy of Bedside Lung Ultrasonography in Emergency (BLUE) protocol for the diagnosis of pulmonary embolismP610Right ventricular systolic dysfunction and its incidence in breast cancer patients submitted to anthracycline therapyP611Right ventricular dysfunction is an independent predictor of survival among cirrhotic patients undergoing liver transplantCongenital heart diseaseP612Hypoplasia or absence of posterior leaflet: a rare congenital anomaly of the mitral valveP613ECHO screening for Barlow disease in proband's relativesDiseases of the aortaP614Aortic size distribution and prognosis in an unselected population of patients referred for standard transthoracic echocardiographyP615Abdominal aorta aneurysm ultrasonographic screening in a large cohort of asympromatic volounteers in an Italian urban settingP616Thoracic aortic aneurysm and left ventricular systolic functionStress echocardiographyP617Wall motion score index, systolic mitral annulus velocity and left ventricular mass predicted global longitudinal systolic strain in 238 patients examined by stress echocardiographyP618Prognostic parameters of exercise-induced severe mitral valve regurgitation and exercise-induced systolic pulmonary hypertensionP619Risk stratification after myocardial infarction: prognostic value of dobutamine stress echocardiographyP620relationship between LV and RV myocardial contractile reserve and metabolic parameters during incremental exercise and recovery in healthy children using 2-D strain analysisP621Increased peripheral extraction as a mechanism compensatory to reduced cardiac output in high risk heart failure patients with group 2 pulmonary hypertension and exercise oscillatory ventilationP622Can exercise induced changes in cardiac synchrony predict response to CRT?Transesophageal echocardiographyP623Fully-automated software for mitral valve assessment in chronic mitral regurgitation by three-dimensional transesophageal echocardiographyP624Real-time 3D transesophageal echocardiography provides more accurate orifice measurement in percutaneous transcatheter left atrial appendage closureP625Percutaneous closure of left atrial appendage: experience of 36 casesReal-time three-dimensional TEEP626Real-time three-dimensional transesophageal echocardiography during pulmonary vein cryoballoon ablation for atrial fibrilationP627Three dimensional ultrasound anatomy of intact mitral valve and in the case of type 2 disfunctionTissue Doppler and speckle trackingP629Left ventricle wall motion tracking from echocardiographic images by a non-rigid image registrationP630The first experience with the new prototype of a robotic system for remote echocardiographyP631Non-invasive PCWP influence on a loop diuretics regimen monitoring model in ADHF patients.P632Normal range of left ventricular strain, dimensions and ejection fraction using three-dimensional speckle-tracking echocardiography in neonatesP633Circumferential ascending aortic strain: new parameter in the assessment of arterial stiffness in systemic hypertensionP634Aortic vascular properties in pediatric osteogenesis imperfecta: a two-dimensional echocardiography derived aortic strain studyP635Assessment of cardiac functions in children with sickle cell anemia: doppler tissue imaging studyP636Assessment of left ventricular function in type 1 diabetes mellitus patients by two-dimensional speckle tracking echocardiography: relation to duration and control of diabetesP637A study of left ventricular torsion in l-loop ventricles using speckle-tracking echocardiographyP638Despite No-Reflow, global and regional longitudinal strains assessed by two-dimensional speckle tracking echocardiography are predictive indexes of left ventricular remodeling in patients with STEMIP639The function of reservoir of the left atrium in patients with medicaly treated arterial hypertensionP640The usefulness of speckle tracking analysis for predicting the recovery of regional systolic function after myocardial infarctionP641Two dimensional speckle tracking echocardiography in assessment of left ventricular systolic function in patients with rheumatic severe mitral regurgitation and normal ejection fractionP642The prediction of left-main and tripple vessel coronary artery disease by tissue doppler based longitudinal strain and strain rate imagingP643Role of speckle tracking in predicting arrhythmic risk and occurrence of appropriate implantable defibrillator Intervention in patients with ischemic and non-ischemic cardiomyopathyComputed Tomography & Nuclear CardiologyP644Cardiac adrenergic activity in patients with nonischemic dilated cardiomyopathy. Correlation with echocardiographyP645Different vascular territories and myocardial ischemia, there is a gradient of association?

Author

Martins Fernandes, S, primary, Badano, L, primary, Garcia Campos, A, primary, Erdei, T, primary, Mehdipoor, G, primary, Hanboly, N, primary, Michalski, BW, primary, Vriz, O, primary, Mo, VY, primary, Le, T T, primary, Ribeiro, JM, primary, Ternacle, J, primary, Yurdakul, SELEN, primary, Shetye, A, primary, Stoebe, S, primary, Lisowska, A, primary, Chinali, M, primary, Orabona, M, primary, Contaldi, C, primary, De La Chica, JA, primary, Codolosa, JN, primary, Trzcinski, P, primary, Prado Diaz, S, primary, Morales Portano, J D, primary, Ha, SJ, primary, Valente, F, primary, Joseph, G, primary, Scali, MC, primary, Cordeiro, F, primary, Duchateau, N, primary, Fabris, E, primary, Costantino, MF, primary, Cho, I J, primary, Goublaire, C, primary, Lam, W, primary, Galli, E, primary, Kim, KH, primary, Mariani, M, primary, Malev, E, primary, Zuercher, F, primary, Tang, Z, primary, Cimino, S, primary, Mahia, P, primary, Petrovic, J, primary, Ciobotaru, V, primary, Remsey- Semmelweiss, E, primary, Kogoj, P, primary, Guerreiro, S, primary, Saxena, A, primary, Mozenska, O, primary, Pontone, G, primary, Macaya Ten, F, primary, Caballero, L, primary, Avegliano, G, primary, Halmai, L, primary, Reis, L, primary, Trifunovic, D, primary, Gospodinova, M, primary, Makavos, G, primary, D'ascenzi, F, primary, Dantas Tavares De Melo, M, primary, Bonapace, S, primary, Kulkarni, A, primary, Cameli, M, primary, Ingvarsson, A, primary, Driessen, MMP, primary, Tufekcioglu, O, primary, Radulescu, D, primary, Barac, A, primary, Cioffi, G, primary, Almeida Morais, L, primary, Ledakowicz-Polak, A, primary, Portugal, G, primary, Naksuk, N, primary, Parato, V M, primary, Kovalova, S, primary, Cherubini, A, primary, Corrado, G, primary, Wierzbowska-Drabik, K, primary, Lesevic, H, primary, Laredj, N, primary, Pieles, G E, primary, Generati, G, primary, Van Zalen, JJ, primary, Aquila, I, primary, Cheng, H-L, primary, Lanzoni, L, primary, Asmarats Serra, L, primary, Kadrabulatova, S, primary, Ranjbar, S, primary, Szczesniak-Stanczyk, D, primary, Sharka, I, primary, Di Salvo, G, primary, Ben Kahla, S, primary, Li, L, primary, Hadeed, HA, primary, Habeeb, H A, primary, Toscano, A, primary, Granata, F, primary, Djikic, D, primary, Wdowiak-Okrojek, K, primary, Girgis, H Y A, primary, Sharma, A, primary, Soro, C, primary, Gallego Page, J C, primary, Corneli, M, primary, Teixeira, R, additional, Roussin, I, additional, Lynch, M, additional, Muraru, D, additional, Romeo, G, additional, Ermacora, D, additional, Marotta, C, additional, Aruta, P, additional, Cucchini, U, additional, Iliceto, S, additional, Martin-Fernandez, M, additional, De La Hera Galarza, JM, additional, Corros-Vicente, C, additional, Colunga Blanco, S, additional, Velasco-Alonso, E, additional, Leon-Aguero, V, additional, Rodriguez-Suarez, ML, additional, Moris De La Tassa, C, additional, Edwards, J, additional, Braim, D, additional, Price, C, additional, Fraser, AG, additional, Salmani, F, additional, Arjmand Shabestari, A, additional, Szymczyk, E, additional, Kupczynska, K, additional, Peczek, L, additional, Nawrot, B, additional, Lipiec, P, additional, Kasprzak, JD, additional, Driussi, C, additional, Ferrara, F, additional, Brosolo, G, additional, Antonini-Canterin, F, additional, Magne, J, additional, Aboyans, V, additional, Bossone, E, additional, Bellucci, BM, additional, Fisher, JM, additional, Balekian, AA, additional, Idapalapati, S, additional, Huang, F, additional, Wong, JI, additional, Tan, RS, additional, Madeira, M, additional, Almeida, I, additional, Reis, L, additional, Siserman, A, additional, Dinis, P, additional, Dias, L, additional, Ramos, AP, additional, Goncalves, L, additional, Wan, FW, additional, Sawaki, DS, additional, Dubois-Rande, JLDR, additional, Adnot, SA, additional, Czibik, GC, additional, Derumeaux, GD, additional, Ercan, G, additional, Tekkesin, ILKER, additional, Sahin, ST, additional, Cengiz, B, additional, Celik, G, additional, Demircan, S, additional, Aytekin, SAIDE, additional, Razvi, NA, additional, Nazir, SA, additional, Price, N, additional, Khan, JN, additional, Kanagala, P, additional, Singh, A, additional, Squire, I, additional, Mccann, GP, additional, Langel, M, additional, Pfeiffer, D, additional, Hagendorff, A, additional, Ptaszynska-Kopczynska, K, additional, Marcinkiewicz-Siemion, M, additional, Knapp, M, additional, Witkowski, M, additional, Musial, WJ, additional, Kaminski, K, additional, Natali, B, additional, D' Anna, C, additional, Leonardi, B, additional, Secinaro, A, additional, Pongiglione, G, additional, Rinelli, G, additional, Renard, S, additional, Michel, N, additional, Mancini, J, additional, Haentjens, J, additional, Sitbon, O, additional, Habib, G, additional, Imbriaco, M, additional, Alcidi, G, additional, Santoro, C, additional, Buonauro, A, additional, Lo Iudice, F, additional, Lembo, M, additional, Cuocolo, A, additional, Trimarco, B, additional, Galderisi, M, additional, Mora Robles, J, additional, Roldan Jimenez, MA, additional, Mancisidor, MA, additional, De Mora, MA, additional, Alnabelsi, T, additional, Goykhman, I, additional, Koshkelashvili, N, additional, Romero-Corral, A, additional, Pressman, GS, additional, Michalski, BW, additional, Miskowiec, D, additional, Montoro Lopez, N, additional, Refoyo Salicio, E, additional, Valbuena Lopez, SC, additional, Gonzalez, O, additional, Alvarez, C, additional, Moreno Yanguela, M, additional, Bartha Rasero, JL, additional, De La Calle, M, additional, Guzman Martinez, G, additional, Suarez-Cuenca, JA, additional, Merino, JA, additional, Gomez Alvarez, E B, additional, Delgado, LG, additional, Woo, YM, additional, Bang, WD, additional, Sohn, GH, additional, Cheong, SS, additional, Yoo, SY, additional, Rodriguez Palomares, JF, additional, Gutierrez, L, additional, Maldonado, G, additional, Pineda, V, additional, Galian, L, additional, Teixido, G, additional, Gonzalez Allujas, MT, additional, Evangelista, A, additional, Garcia Dorado, 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2015
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27. Poster session 1GENERAL PRINCIPLESP194Ultrasound indexes of adipose tissue and lipid goals attainment in high and very high cardiovascular risk patientsTHE IMAGING EXAMINATIONP195Right ventricular global longitudinal strain provides higher prognostic value than right free wall longitudinal strain in patients with left heart diseaseP196Normal values of echocardiographlc left and right cardiac chambers dimensions as multifactorially determined by sex, level of physical activity, age, BMI, systolic blood pressure and heart rateAnatomy and physiology of the heart and great vesselsP197Echocardiographic phenotypes according to levels of oxygen consumption at peak exercise: findings from the EURO(pean) EX(ercise) population-based studyAnatomy and physiology of the heart and great vesselsP198Systemic vascular resistance and central arterial stiffness in relation to left ventricular geometry and diastolic function in essential hypertensionAssessment of diameters, volumes and massP199Left atrial diameter predicts a new diagnosis of paroxysmal atrial fibrillation in a population presenting with palpitationsP200Interventricular septum thickness and acute coronary syndromes: small differences, big prognostic influence?P201Detection of abdominal aortic aneurysm in a population referred for an ultrasonographyAssessments of haemodynamicsP202The ultrasound vector velocity method transverse oscillation validated in a flowrig with constant and pulsatile flow and in-vivo of blood flow in the ascending aortaASSESSMENT OF SYSTOLIC FUNCTIONP203Different types of left ventrical remodeling in children with arterial hypertensionP204Assessment of myocardial performance index in hypertensive patients with or without hyperuricemiaP205Strain echocardiography detects mild impairment of systolic function in patients with frequent premature ventricular contractionsP206Speckle tracking strain correlates better with functional capacity and hemodynamic burden than ejection fraction in patients with severe heart failureP207Prognostic value of 2D and 3D echocardiographic volumes, ejection fraction and strain as markers of abnormal left ventricular performanceP208Long-term prognostic value of left ventricular ejection fraction assessed by echocardiography and magnetic resonance imaging after acute STEMIP209Assessment of left ventricular function after percutaneous coronary intervention of chronic total occluded coronary artery by speckle tracking and cardiac magnetic resonanceP210Physiologic variations of tricuspid annular plane systolic excursion in healthy subjects: clinical and echocardiographic correlatesP211Predictors of incipient ventricular dysfunction with tyrosine kinase inhibitors in metastatic renal cell carcinomaAssessment of diastolic functionP212Disagreement between the American Society of Echocardiography (ASE) and gastroenterology-based guidelines for the diagnosis of diastolic dysfunction among patients with advanced liver diseaseP213Nomograms for mitral inflow doppler and tissue doppler velocities in caucasian childrenP215Diastolic function is impaired in women with angina pectoris and no obstructive coronary artery disease independently of coronary microvascular functionP216Clinical value of myocardial performance index in patients with isolated diastolic dysfunctionIschemic heart diseaseP217Cardiac imaging strategy is clinically more effective and at lower cost than traditional ETT strategy for the diagnosis of stable coronary artery diseaseP218Does the ESC clinical pretest probability score stratify our patients correctly? Validation with stress echocardiographyP219Incremental value of exercise echocardiography over exercise electrocardiography in a chest pain unit: a decision curve analysisP220A bedside echocardiographic score for risk stratification of ST-elevation myocardial infarction patients undergoing primary percutaneous coronary interventionP221Interventricular and intraventricular dyssynchrony in patients with Q-wave acute myocardial infarctionP222Comparison of tagging and tissue tracking for myocardial strain assessment at 1.5T and 3.0T following ST-segment elevation myocardial infarctionP223Left atrial strain rate evaluated by two-dimensional speckle tracking is predictor of left ventricular arrhythmias in STEMI patients treated by primary PCIP224Impact of percutaneous coronary intervention of chronic total oclussion on left ventricular function using speckle tracking and cardiac magnetic resonanceHeart valve DiseasesP225Clinical and echocardiographic characteristics of patients with low flow severe aortic stenosis and preserved ejection fractionP226Ventricular-arterial interplay in patients with severe aortic stenosis: additional role of wave intensity analysisP227Degenerative aortic stenosis: don't forget the vascular componentP228Reclassifying low gradient aortic stenosis with 3D transesophageal echocardiography and global longitudinal strainP229Importance of mitral regurgitation on pre- and postoperative clinical status and echocardiographic findings in patients with severe aortic stenosis admitted for aortic valve replacementsP230Aorto-septal angle and degenerative aortic stenosis: a case-control study stenosisP231Difference of sST2 level in mitral stenosis compare with control subjectsP232Velocity-time integral of aortic regurgitation: a novel echocardiographic marker in the evaluation of aortic regurgitation severityP233Color doppler 3D echocardiography-derived regurgitant volume in primary mitral regurgitation: a comparison of different techniques with magnetic resonanceP234Outcome of surgery for degenerative mitral regurgitationP235Mitral valve repair or replacement for functional regurgitation and left ventricular dysfunction: clinical and echocardiographic outcomeP236Prevalence, characteristics and prognosis of moderate to severe tricuspid regurgitation in patients with precapillary pulmonary hypertensionP237Management of late bioprosthetic mitral valve thrombosisP238Relationship between pulmonary venous flow and prosthetic mitral valve thrombosisP239Transcatheter aortic valve implantation does not reduce acutely valvuloarterial impedance in an elderly population with degenerative calcific aortic valve stenosisP240Influence of type of prosthesis on mitral regurgitation change after transcatheter aortic valve replacement for aortic stenosisP241The prevalence of valve disease in patients undergoing atrial fibrillation ablationCardiomyopathiesP242The prognostic value of lung ultrasound at discharge in heart failureP243Prognostic value of global longitudinal strain in non-ischaemic dilated cardiomyopathyP244Additional effect of high intensity exercise training to cardiac resynchronization in heart failure: the reduction on left venticular massP245Dobutamine-induced changes of longitundinal strain predicts longterm mortality in severe heart failureP246Myocardial fibrosis is not related to two-dimensional longitudinal strain in dilated cardiomyopathyP247Echocardiographic parameters are predictors of positive genetic study in a Portuguese population with hypertrophic cardiomyopathy: a multicentre studyP248Myocardial deformation techniques for the evaluation of the right ventricle in fabry diseaseP249Borderline hypertrophic cardiomyopathy or athlete's heart: what is the role for genetic testing in athletes?P250Isolated papillary muscle hypertrophy. Clinical, electrocardiographic and morphologic characteristicsP251Prognostic value of the assessment of left atrial deformation in hypertrophic cardiomyopathyP252Assessment of subtle echocardiographic changes may improve risk stratification of arrhythmias in early stages of arrhythmogenic right ventricular cardiomyopathy (ARVC)P253Long-term correlation of electrocardiography with structural echocardiography changes in patients with arrhythmogenic right ventricular cardiomyopathyP254Right ventricular strain and dyssynchrony assessment in arrhythmogenic right ventricular cardiomyopathy: a cardiac magnetic resonance feature-tracking studyP255Association of non compaction and hypertrophic cardiomyopathies, Noonan and long QT syndromesP256Predictors of mortality in patients with acute myocarditisP257Clinical characteristics and natural history of acute myocarditisP258One-beat 3dimensional echocardiography for the assessment of right ventricular function in heart transplant recipientsP259Hemodynamically irrelevant, non-surgery related pericardial effusion is a predictor of mortality in heart transplanted patientsSystemic diseases and other conditionsP260Left ventricular function as a cardiac marker of target organ damage in non-diabetic, never treated hypertensive patients: Camparison with microalbuminuriaP261Subclinical myocardial dysfunction in hypertensive patients with hyperuricemiaP262Can deformation indices (strain/strain rate) establish differential diagnosis in infiltrative cardiomyopathies?P263Prevalence and factors associated with inappropriately high left ventricular mass in patients with rheumatoid arthritisP264Echocardiographic evaluation of patients with end-stage liver disease, the importance of follow up after liver transplantationP265Cardiovasclular involvement in asymptomatic juvenile localized scleroderma patientsP267Can the left ventricular mechanics using speckle tracking echocardiography in pregnancy predict the new onset heart failure?P268What causes impaired exercise tolerance in HFpEF? Relative contribution from LV filling pressure and other factorsCongenital heart diseaseP269Pregnancy in patients with Ebsteins anomaly - echocardiographic and clinical studyP270Double aortic arch anomalies in clinical practiceP271Echocardiography as the essential imaging modality in congenital heart disease - first one to begin with and the one who staysMasses, tumors and sources of embolismP272Can the reduction of wall shear stress in diskinetic myocardial wall segments be used to predict trombogenicity?Diseases of the aortaP273The role of modified transoesophageal echocardiography for optimal access decision making for transcatheter aortic valve replacement proceduresStress echocardiographyP274Is aortic valve resistance different in patients with severe aortic stenosis and left ventricular fraction below 40% with low or high gradient?P275Does wall motion score index in dobutamine stress echocardiography predict syntax score in catheterization lab?P276Sex-related differences in peak stress left ventricular global longitudinal strain during dobutamine stress echocardiography in patients with significant coronary artery diseaseP277Exercise stress echocardiography complications: a 4-year single center experienceP278Reduced baseline left ventricular longitudinal systolic function is a marker of inducible myocardial ischemia in patients undergoing exercise echocardiographyP279Estimation of mean pulmonary arterial pressure based on right ventricle systolic pressure observed from exercise echocardiography among non-pulmonary hypertension with systemic sclerosisTransesophageal echocardiographyP280Transoesophageal echocardiography in patients with neuroendocrine tumour and carcinoid symptoms is safe without intravenous octreotideP281The feasibility and the clinical benefit of the cognitive-behavioral intervention for preparing patients for transesophageal echocardiographic studyP282Dynamic changes of mitral annulus shape in different types of mitral valve prolapse. A three-dimensional transoesophageal studyReal-time three-dimensional TEEP283Severe aortic stenosis: evaluation of effective and anatomy valve by 2D transthoracic echocardiography and 3D transesophageal echocardiographyP2843D-transeosphageal echocardiography usefulness for assessment of cardiac output in intensive care unit: an ultrasound versus thermodilution comparative study for patients under mechanical ventilationP285The predictive value of three-dimensional vena-contracta in determining the number of MitraClip devices needed during the procedure in functional mitral regurgitationTissue Doppler and speckle trackingP286Should the septum be included in the assessment of right ventricular longitudinal strain?P287Can machine learning help to identify heart failure with preserved ejection fraction?P288Concordance of atrial function measurement by 3D volumetric echocardiography and speckle tracking deformation imagingP289Heterogonous regional diastolic function revealed by 2D speckle tracking echocardiography identifies patients with ischemic etiology of left ventricular systolic dysfunctionP290The values from Real time 3-dimensional strain is not independent from preload changesP291Risk stratification in hypertrophic cardiomyopathy. a potential role for speckle-tracking parameters by cardiac magnetic resonanceP292Abnormal longitudinal peak systolic strain in asymptomatic patients with type-I diabetes mellitusP294Strain evaluation of subclinical cardiac dysfunction in patients with myotonic dystrophy type 1P295Heart function assessment in perinatal asphyxia; speckle tracking indices from greyscale recordings perform better than from tissue Doppler recordings, fractional shortening and tissue Doppler indicesP297Longitudinal strain assessed by automatic function imaging - a useful tool in significant coronary artery disease detection in patients with low risk anginaP298Global 2-Dimensional strain as a predictor of mortality in heart transplant patients with cardiac allograft vasculopathyP299Two-dimensional longitudinal strain and strain rate in asymptomatic middle-aged patients with type 2 diabetes mellitus - a pilot study resultsP300Limited accuracy of myocardial deformation imaging in diagnosis of left ventricular segmental dysfunction in patients with acute myocardial infarction: is it only a limitation of the strain software?Computed Tomography & Nuclear CardiologyP301Evaluation of the actual prevalence of myocardial ischemia in patients prior to performing a peripheral vascular surgeryP302Prognostic value of myocardial ischemia detected by myocardial perfusion imaging in asymptomatic patients with diabetes type 2P303Economic cost analysis derived by coronary computed tomography angiography inappropriate indications to rule out coronary heart disease

Author

Haberka, M, primary, Garcia Martin, A, primary, Barbier, P, primary, Pellegrino, M, primary, Angelis, A, primary, Howlett, PJ, primary, Madeira, M, primary, Carrero, PJ, primary, Hansen, KL, primary, Trunina, I, primary, Basar, C, primary, Lie, OH, primary, Sade, LE, primary, Gopal, A S, primary, Klug, G, primary, Rodriguez Gonzalez, E, primary, Ferrara, F, primary, Moustafa, S, primary, Naksuk, N, primary, Cantinotti, M, primary, Michelsen, MM, primary, Fernandes, JMG, primary, Demir, OM, primary, Cano Carrizal, R, primary, Bouzas-Mosquera, A, primary, Leao, S, primary, Kuznetsov, VA, primary, Nazir, S A, primary, Trifunovic, D, primary, Spampinato, RA, primary, Antonini-Canterin, F, primary, Ribeiro, JM, primary, Morgado, GJ, primary, Reis, L, primary, Naratrekoon, B, primary, Soto-Ruiz, RM, primary, Penicka, M, primary, Zilberszac, R, primary, De Chiara, B, primary, Rifai, R, primary, Gunduz, S, primary, Cersit, S, primary, Devecchi, C, primary, Ancona, F, primary, Smith, D, primary, Gargani, L, primary, Asmarats Serra, L, primary, Abreu, A, primary, Ikonomidis, I, primary, Biernacka, B, primary, Gomes, AC, primary, Caballero, L, primary, Mansencal, N, primary, Venturini, C, primary, Zaroui, A, primary, Leren, I S, primary, Astrom Aneq, M, primary, Nucifora, G, primary, Rocon, CRLA, primary, Cho, J Y, primary, Stampfli, S F, primary, Cho, EJ, primary, Stevanovic, A, primary, Pena, J L, primary, Ognibeni, F, primary, Colunga, S, primary, Borowiec, A, primary, Hristova, K, primary, Kosmala, W, primary, Lesniak-Sobelga, A M, primary, Kaldararova, M, primary, Stanojevic, D, primary, Carbonell San Roman, A, primary, Hoetink, A, primary, Ferreira, R, primary, Rohani, A, primary, Wierzbowska-Drabik, K, primary, Carvalho, J F, primary, Cherubini, A, primary, Teramoto, K, primary, May, CJH, primary, Wejner-Mik, P, primary, Gurzun, M M, primary, Perea, GO, primary, Laveau, F, primary, Mahmoud, HM, primary, Sanz, M, primary, Sanchez-Martinez, S, primary, Montserrat, S, primary, Kowalczyk, E, primary, Park, CS, primary, Hinojar, R, primary, Van Berendoncks, A M, primary, Guedes, H, primary, Nestaas, E, primary, Onut, R, primary, Moran, L, primary, Kisko, A, primary, Agmon, Y, primary, Corneli, M, primary, Peovska Mitevska, IPM, primary, Barreiro Perez, M, primary, Banska, K, additional, Gasior, Z, additional, Moya-Mur, JL, additional, Carbonell-San Roman, S-A, additional, Rodriguez-Munoz, D, additional, Garcia-Lledo, A, additional, Casas-Rojo, E, additional, Hinojar, R, additional, Jimenez-Nacher, JJ, additional, Fernandez-Golfin, C, additional, Zamorano-Gomez, JL, additional, Ravani, A, additional, Cefalu, C, additional, Maltagliati, A, additional, Frigerio, B, additional, Sansaro, D, additional, Amato, M, additional, Baldassarre, D, additional, Bandera, F, additional, Generati, G, additional, Labate, V, additional, Alfonzetti, E, additional, Guazzi, M, additional, Aggeli, K, additional, Ioakeimidis, N, additional, Abdelrasoul, M, additional, Felekos, I, additional, Gourgouli, I, additional, Aznaouridis, K, additional, Rousakis, G, additional, Vlachopoulos, C, additional, Tousoulis, D, additional, Darasz, K, additional, Mahmoudi, M, additional, Shah, N, additional, Jabr, RI, additional, Hickman, M, additional, Leatham, EW, additional, Fry, CH, additional, Teixeira, R, additional, Almeida, I, additional, Caetano, F, additional, Fernandes, A, additional, Cassandra, M, additional, Reis, L, additional, Costa, M, additional, Goncalves, L, additional, Nielsen, AJ, additional, Carrero, MC, additional, Saubidet, GL, additional, Peralta, SP, additional, Moeller-Soerensen, H, additional, Kjaergaard, J, additional, Jensen, MB, additional, Lund, JT, additional, Pedersen, MM, additional, Olesen, JB, additional, Jensen, JA, additional, Nielsen, MB, additional, Sharykin, AS, additional, Karelina, EV, additional, Telezhnikova, ND, additional, Ozhan, H, additional, Kayapinar, O, additional, Albayrak, ES, additional, Saberniak, J, 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P, additional, Portugal, G, additional, Rio, P, additional, Branco, L, additional, Ferreira, R, additional, Mota Carmo, M, additional, Paraskevaidis, I, additional, Papadopoulos, C, additional, Stasinos, V, additional, Parissis, J, additional, Lekakis, J, additional, Rubis, P, additional, Gackowski, A, additional, Wisniowska-Smialek, S, additional, Lesniak-Sobelga, A, additional, Kostkiewicz, M, additional, Bento, D, additional, Correia, E, additional, Teles, L, additional, Picarra, B, additional, Lourenco, C, additional, Faria, R, additional, Domingues, K, additional, Azevedo, O, additional, Climent Paya, V, additional, Martinez Moreno, M, additional, Gimeno, JR, additional, Oliva, MJ, additional, Saura, D, additional, Sanchez Quinones, J, additional, Garcia Honrubia, A, additional, Valdes, M, additional, De La Morena, G, additional, Richard, P, additional, Guerard, S, additional, Brion, R, additional, Paul, P, additional, Dubourg, O, additional, Komajda, M, additional, Isnard, R, additional, Arslan, M, additional, Charron, P, additional, Avegliano, G, additional, Andres, S, additional, Costabel, JP, additional, Kuschnir, P, additional, Sciancalepore, A, additional, Mendoza, O, additional, Perea, G, additional, Ronderos, R, additional, Ben Said, RYM, additional, EL Chalbia, TEJ, additional, Wali, SANA, additional, Mourali, MS, additional, Mechmeche, RACHID, additional, Haland, TF, additional, Svetlichnaya, J S, additional, Shikha, SS, additional, Scheinmann, MS, additional, Klein, LK, additional, Prati, G, additional, Vitrella, G, additional, Allocca, G, additional, Cukon Buttignoni, S, additional, Muser, D, additional, Morocutti, G, additional, Pinamonti, B, additional, Sinagra, G, additional, Proclemer, A, additional, Melo, MDTM, additional, Bocchi, EAB, additional, Araujo, JABAF, additional, Demarchi, LMMFD, additional, Mady, CM, additional, Biselli, BB, additional, Kalil, RKF, additional, Salemi, VMCS, additional, Tuma, RT, additional, Kim, K H, additional, Yoon, H J, additional, Lee, K J, additional, Park, H, additional, Kim, J H, additional, Ahn, Y, additional, Jeong, M H, additional, Cho, J G, additional, Park, J C, additional, Park, H J, additional, Kozan, H, additional, Sezgin, A, additional, Aydinalp, A, additional, Oezkartal, T, additional, Bernhart, S, additional, Flammer, AJ, additional, Vecchiati, A, additional, Froehlich, GM, additional, Ruschitzka, F, additional, Tanner, FC, additional, Choi, KY, additional, Kim, DB, additional, Jang, SW, additional, Cho, JS, additional, Park, CS, additional, Jung, HO, additional, Jeon, HK, additional, Youn, HJ, additional, Dekleva, M, additional, Fortes, PRL, additional, Passos, BR, additional, Rodrigues, AB, additional, Sampaio, IH, additional, Oliveira, MCN, additional, Silva, MG, additional, Cardoso, RAF, additional, Tofani, FA, additional, Moreira, MCV, additional, Cioffi, G, additional, Viapiana, O, additional, Dalbeni, A, additional, Fracassi, E, additional, Di Nora, C, additional, Cherubini, A, additional, Mazzone, C, additional, Di Lenarda, A, additional, Rossini, M, additional, Corros, C, additional, Garcia-Campos, A, additional, Martin, M, additional, Rodriguez-Suarez, M, additional, Leon, V, additional, Fidalgo, A, additional, Lopez-Iglesias, F, additional, Moris, C, additional, De La Hera, JM, additional, Dabrowski, R, additional, Wozniak, J, additional, Jasek, S, additional, Chwyczko, T, additional, Kowalik, I, additional, Musiej-Nowakowska, E, additional, Szwed, H, additional, Marinov, R, additional, Stamenov, G, additional, Mihova, M, additional, Chacheva, K, additional, Persenska, S, additional, Racheva, A, additional, Przewlocka-Kosmala, M, additional, Rojek, A, additional, Karolko, B, additional, Mysiak, A, additional, Marwick, TH, additional, Biernacka, B, additional, Tittel, P, additional, Kardos, M, additional, Vrsanska, V, additional, Ondriska, M, additional, Hraska, V, additional, Nosal, M, additional, Masura, J, additional, Simkova, I, additional, Apostolovic, S, additional, Salinger-Martinovic, S, additional, Jankovic-Tomasevic, R, additional, Djordjevic-Radojkovic, D, additional, Stanojlovic, T, additional, Atanaskovic, V, additional, Pavlovic, M, additional, Tahirovic, E, additional, Dungen, HD, additional, Moya Mur, JL, additional, Lozano Granero, C, additional, Jimenez Nacher, JJ, additional, Gonzalez Gomez, A, additional, Fraile Sanz, C, additional, Segura De La Cal, T, additional, Zamorano Gomez, JL, additional, Jansen Klomp, WW, additional, Van 'T Hof, AWJ, additional, Brandon Bravo Bruinsma, GJ, additional, Spanjersberg, AJ, additional, Grandjean, J, additional, Nierich, AP, additional, Ferreira, J, additional, Lazaro Mendes, S, additional, Martins, R, additional, Monteiro, S, additional, Pego, M, additional, Khamene Bagheri, R, additional, Peruga, JZ, additional, Sobczak, M, additional, Plewka, M, additional, Wcislo, T, additional, Krecki, R, additional, Kasprzak, JD, additional, Morgado, G, additional, Cruz, I, additional, Almeida, AR, additional, Joao, I, additional, Lopes, L, additional, Cotrim, C, additional, Faganello, G, additional, Pandullo, C, additional, Russo, G, additional, Stefenelli, C, additional, Furlanello, F, additional, Tarantini, L, additional, Suzuki, K, additional, Satoh, Y, additional, Minami, K, additional, Mizukoshi, K, additional, Kamijima, R, additional, Kou, S, additional, Takai, M, additional, Izumo, M, additional, Akashi, YJ, additional, Ayuk, J, additional, Geh, I, additional, Shah, T, additional, Edwards, NC, additional, Steeds, RP, additional, Miskowiec, D, additional, Wdowiak-Okrojek, K, additional, Lipiec, P, additional, Rosca, M, additional, Calin, A, additional, Beladan, C, additional, Serban, M, additional, Ginghina, C, additional, Popescu, BA, additional, Lombardero, M, additional, Henquin, R, additional, Corneli, M, additional, Tinetti, M, additional, Hekimian, G, additional, Achkar, M, additional, Combes, A, additional, Hammoudi, N, additional, Al-Ghamdi, M, additional, Ghabashi, A, additional, Ezzat, M H, additional, Al-Amin, A, additional, Giraldeau, G, additional, Sarvari, SI, additional, Marin, J, additional, Brambila, C, additional, Gabrielli, L, additional, Bijnens, B, additional, Sitges, M, additional, Duchateau, N, additional, Erdei, T, additional, Fraser, A, additional, Bijnens, B H, additional, Piella, G, additional, Sanchis, L, additional, Borras, R, additional, Vidal, B, additional, Prat, S, additional, Azqueta, M, additional, Pare, C, additional, Grazioli, G, additional, Sanz, M, additional, Wejner-Mik, P, additional, Jung, MH, additional, Ahn, HS, additional, Kim, JH, additional, Megias, A, additional, Alonso, GL, additional, Gonzalez-Gomez, A, additional, Rincon, LM, additional, Esteban, A, additional, Fernandez Mendez, MA, additional, Barrios, V, additional, Zamorano, JL, additional, Van Gaal, L, additional, De Block, C, additional, Salgado, R, additional, Vrints, C, additional, Shivalkar, B, additional, Pereira, A, additional, Santos, R, additional, Marques, L, additional, Moreno, N, additional, Carvalho, R, additional, Pires, M, additional, Sousa, R, additional, Andrade, A, additional, Pinto, P, additional, Stoylen, A, additional, Fugelseth, D, additional, Tautu, O, additional, Onciul, S, additional, Marinescu, C, additional, Zamfir, D, additional, Dorobantu, M, additional, Sanchez Sanchez, V, additional, Navas, P, additional, Garcia-Cosio, D, additional, Diaz, B, additional, Carballo-Alzola, L, additional, Lombera, F, additional, Delgado, J, additional, Babcak, M, additional, Kishko, N, additional, Eitan, A, additional, Mutlak, D, additional, Kehat, I, additional, Meretta, AH, additional, Perea, GO, additional, Belcastro, F, additional, Aguirre, E, additional, Rosa, D, additional, Zaefferer, P, additional, Masoli, O, additional, Srbinovska, ES, additional, Bosevski, MB, additional, Antova, EA, additional, Pop Gorceva, DPG, additional, Martin Fernandez, M, additional, Costilla Garcia, SM, additional, Diaz Pelaez, E, additional, and Moris De La Tassa, C, additional

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2015
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28. Moderated Posters session: complementary role of imaging techniquesP184Submillisievert computed tomography with model-based iterative reconstruction before pulmonary veins radiofrequency catheter ablation of atrial fibrillation: impact on radiation exposure and outcomeP185Calcium score and CT coronary angiography can be a low cost strategy for the investigation of patients with chest pain with low and intermediate predicted riskP186Impact of imaging modality on the heritability estimates of aortic root geometry: a classical twin studyP187Diagnosis of cardiac allograft vasculopathy with cardiac CT. Relation between clinical variables and mid-term prognosisP188Stress-only normal SPECT myocardial perfusion imaging: is it enough?P189Global longitudinal strain and its relation to cardiac autonomic denervation as assessed by 123-mIBG scintigraphy: insights from the BETTER-HF trialP190FDG-PET imaging in suspected inflammatory cardiomyopathies : comparison with the classical pattern of cardiac sarcoidosis and impact on diagnosisP191CT coronary angiography can be an effective alternative to imaging stress tests in patients with high pre-test probability of CADP192Outcomes at long term follow up of subclinical and mild coronary artery disease diagnosed with MDCT in Mediterranean EuropeP193Cardiac ct peri-device flow after percutaneous left atrial appendage closure using the amplatzer cardiac plug device

Author

Pontone, G, primary, Demir, OM, primary, Celeng, C, primary, Llao-Ferrando, JI, primary, Kitsiou, A N, primary, Portugal, G, primary, Becoulet, L, primary, Marcos-Alberca Moreno, P, primary, Iriart, X, primary, Andreini, D, additional, Annoni, A, additional, Petulla, M, additional, Russo, E, additional, Innocenti, E, additional, Guglielmo, M, additional, Mushtaq, S, additional, Tondo, C, additional, Pepi, M, additional, Bashir, A, additional, Marshall, K, additional, Douglas, M, additional, Wasan, B, additional, Plein, S, additional, Alfakih, K, additional, Kolossvary, M, additional, Kovacs, A, additional, Szilveszter, B, additional, Molnar, A, additional, Horvath, T, additional, Jermendy, AL, additional, Tarnoki, AD, additional, Merkely, B, additional, Maurovich-Horvat, P, additional, Castro, JC, additional, Vilades-Medel, D, additional, Mirabet, S, additional, Pons-Llado, G, additional, Roig, E, additional, Leta, R, additional, Papanikolaou, S, additional, Griroriou, K, additional, Antonopoulos, M, additional, Mpouki, M, additional, Moustakas, G, additional, Giougi, A, additional, Giannakopoulos, V, additional, Gionakis, G, additional, Balomenos, A, additional, Abreu, A, additional, Rio, P, additional, Santos, V, additional, Martins Oliveira, M, additional, Silva Cunha, P, additional, Mota Carmo, M, additional, Branco, L M, additional, Morais, L, additional, Cruz Ferreira, R, additional, Guijarro, D, additional, Pallardy, A, additional, Mathieu, C, additional, Valette, F, additional, Gueffet, JP, additional, Serfaty, JM, additional, Kraeber-Bodere, F, additional, Trochu, JN, additional, Piriou, N, additional, Perez-Isla, L, additional, Palacios, J, additional, Gomez De Diego, JJ, additional, Islas, F, additional, De Agustin, JA, additional, Luaces, M, additional, Arrazola, J, additional, Garcia-Fernandez, MA, additional, Macaya, C, additional, Selmi, W, additional, Jalal, Z, additional, and Thambo, JB, additional

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2015
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29. Rapid Fire Abstract session: usefulness of CT and radionuclide imaging in different clinical scenarios378Improving the cost-effectiveness of chest pain investigations using single photon emission computed tomography379Is autonomic nervous dysfunction severity associated to less benefit from cardiac resynchronization therapy?380Validation of stress Thallium-201/Rest Technetium-99m sequential dual isotope high-speed myocardial perfusion imaging against fractional flow reserve for the detection of the extent of ischemia.381Nuclear imaging to predict adverse events in heart failure patients382Autonomic nervous system modulation in patients with heart failure and resynchronization after high intensity interval training383Long-term prediction of cardiac events using low-dose coronary ct angiography with prospective triggering384Left atrial appendage sizing for percutaneous occlusion with Amplatzer cardiac plug: a multimodality imaging approach385Evaluation of PAPVR using cardiac CT or MR imaging in patients with Turner syndrome.

Author

Lagan, J, primary, Rio, P, primary, Barone-Rochette, G, primary, Limeres Freire, J, primary, Abreu, A, primary, Clerc, O F, primary, Iriart, X, primary, Van Den Hoven, AT, primary, Meah, M, additional, Hasleton, J, additional, Mcshane, J, additional, Trent, R, additional, Abreu, A, additional, Santos, V, additional, Santa-Clara, H, additional, Oliveira, L, additional, Martins Oliveira, M, additional, Silva Cunha, P, additional, Moura Branco, L, additional, Mota Carmo, M, additional, Cruz Ferreira, R, additional, Zoreka, FZ, additional, Calizzano, A, additional, Vautrin, E, additional, Quesada, JL, additional, Broisat, A, additional, Riou, L, additional, Baguet, JP, additional, Fagret, D, additional, Ghezzi, C, additional, Rodriguez, J, additional, Oristrell, G, additional, Quiroga, X, additional, Pizzi, N, additional, Perez-Rodon, J, additional, Galve, E, additional, Aguade, S, additional, Santa Clara, H, additional, Oliveira, M, additional, Rio, P, additional, Cunha, P, additional, Portugal, G, additional, Ferreira, R, additional, Kaufmann, B P, additional, Possner, M, additional, Liga, R, additional, Vontobel, J, additional, Mikulicic, F, additional, Graeni, C, additional, Benz, D C, additional, Kaufmann, P A, additional, Buechel, R R, additional, Selmi, W, additional, Jalal, Z, additional, Thambo, JB, additional, Saru-Chelu, RG, additional, Duijnhouwer, AL, additional, Van Hagen, IM, additional, and Roos-Hesselink, JW, additional

Published
2015
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30. Can Metabolic Syndrome Presence Predict Carotid Intima-Media Thickness?

Author

Timóteo, AT, Mota Carmo, M, and Cruz Ferreira, R

Subjects
Adult, Aged, 80 and over, Blood Glucose, Male, Metabolic Syndrome, Aging, Sex Characteristics, Cholesterol, HDL, Middle Aged, HSM CAR, Carotid Intima-Media Thickness, Carotid Arteries, Cross-Sectional Studies, Case-Control Studies, cardiovascular system, Diabetes Mellitus, Humans, Female, cardiovascular diseases, Prospective Studies, Aged
Abstract

The aim of this investigation was to analyze metabolic syndrome (MS) impact on carotid intima-media thickness (cIMT). Prospective study of 300 patients with suspected coronary artery disease admitted for an elective coronary angiography were evaluated. Patients with previously known cardiac disease were excluded. In the population, 23.0% were diabetics and 40.5% had MS (but no diabetes). cIMT was not significantly different in patients with MS, but was significantly higher in diabetic patients compared with MS and control patients. Independent predictors of cIMT were age, male gender, insulin, and high-density lipoprotein (HDL) cholesterol (the last one with an inverse association). In patients without MS, only age and HDL cholesterol were associated. In patients with MS, independent predictors were age, male gender, and glucose, and abdominal obesity showed an inverse relationship. In patients with stable angina, MS is not an independent predictor of cIMT. Nonmodifiable variables (age and gender) are the most important determinants of cIMT, as well as blood glucose, in MS patients. Abdominal obesity was protective. J Clin Hypertens (Greenwich). 2012;00:00-00. ©2012 Wiley Periodicals, Inc. info:eu-repo/semantics/publishedVersion

Published
2012

31. Prevalência de Síndrome Metabólica e Diabetes numa População de Alto Risco com Suspeita de Doença Coronária

Author

Timóteo, AT, Mota Carmo, M, and Cruz Ferreira, R

Subjects
Síndrome Metabólica, Complicações dos Diabetes, Diabetes Mellitus, Estudos Transversais, Prevalência, Doença das Artérias Coronárias, Factores de Risco
Abstract

Objectivos: A prevalência de Sindroma Metabólica (SM) e diabetes é variável consoante a definição utilizada, assim como com a região geográfica e o grupo étnico estudado. Não existem estudos em indivíduos portugueses com suspeita de doença arterial coronária. Analisámos a prevalência de SM e diabetes nesta população específica de doentes, comparando também definições. Métodos: Incluíram-se no estudo 300 indivíduos, com uma idade media de 64 ± 9 anos, 59% do género masculino, admitidos para angiografia coronária electiva, tendo sido excluídos os doentes com doença cardíaca previamente conhecida. Avaliou-se a prevalência de SM e de diabetes. Resultados: A prevalência ajustada de SM foi de 39,3% (critério NCEP-ATP III), 53,8% (critério IDF) e 48,4% (critério AHA/NHLBI). A prevalência ajustada de diabetes foi de 14,8% pela definição prévia da ADA e de 36.4% com a definição mais recente. A concordância global entre as definições de SM foi de 45,3%, sendo mais elevada entre as definições da AHA/NHLBI e da NCEP-ATP III (Kappa 0,821). A prevalência de SM está altamente dependente da idade em ambos os géneros, sendo mais prevalente no género feminino. A prevalência de diabetes é também dependente da idade, sendo semelhante em ambos os géneros. O componente de SM mais frequente é a hipertensão arterial, seguido pela obesidade abdominal, elevação da glicose, colesterol-HDL baixo e finalmente elevação dos triglicéridos. É também importante referir que 60% dos doentes estavam sob terapêutica hipolipemiante (56,6% com estatinas, 1,7% com fibratos e 1,7% com ambos). A diferença mais significativa entre géneros no que diz respeito aos componentes de SM é a elevada prevalência de obesidade abdominal no género feminino. Conclusões: Nesta população de alto risco, a prevalência de SM é elevada, sendo contudo a prevalência de diabetes semelhante à registada em estudos epidemiológicos na população geral.

Published
2012

32. Prevalence of Metabolic Syndrome and Diabetes on a High-Risk Population with Suspected Coronary Artery Disease

Author

Timóteo, AT, Mota Carmo, M, and Cruz Ferreira, R

Subjects
Síndrome Metabólica, Complicações dos Diabetes, Diabetes Mellitus, Estudos Transversais, Prevalência, Doença das Artérias Coronárias, Factores de Risco
Abstract

Submitted by Ana Quininha (ana.quininha@chlc.min-saude.pt) on 2012-12-12T13:08:20Z No. of bitstreams: 1 AMP 2012.pdf: 299426 bytes, checksum: a824375711c56e26fa5cb5a87072f27a (MD5) Made available in DSpace on 2012-12-12T13:08:20Z (GMT). No. of bitstreams: 1 AMP 2012.pdf: 299426 bytes, checksum: a824375711c56e26fa5cb5a87072f27a (MD5) Previous issue date: 2012

Published
2012

33. Does Metabolic Syndrome Predict Significant Angiographic Coronary Artery Disease?

Author

Timóteo, AT, Mota Carmo, M, and Cruz Ferreira, R

Subjects
Síndrome Metabólica, Estudos Prospectivos, Angiografia Coronária, Prognóstico, Estudos Transversais, cardiovascular diseases, Doença das Artérias Coronárias
Abstract

INTRODUCTION: Metabolic syndrome (MS) is an independent predictor of acute cardiovascular events. However, few studies have addressed the relationship between MS and stable angiographic coronary artery disease (CAD), which has a different pathophysiological mechanism. We aimed to study the independent predictors for significant CAD, and to analyze the impact of MS (by the AHA/NHLBI definition) on CAD. METHODS: We prospectively included 300 patients, mean age 64±9 years, 59% male, admitted for elective coronary angiography (suspected ischemic heart disease), excluding patients with known cardiac disease. All patients underwent assessment of demographic, anthropometric, and laboratory data and risk factors, and subsequently underwent coronary angiography. RESULTS: In the study population, 23.0% were diabetic, 40.5% had MS (and no diabetes) and 36.7% had neither diagnosis. Significant CAD was present in 51.3% of patients. CAD patients were older and more frequently male and diabetic, with increased triglycerides and glucose and lower HDL cholesterol. Abdominal obesity was also less prevalent. MS was not associated with the presence of CAD (OR 0.94, 95% CI 0.59-1.48, p=0.778). Of the MS components, the most important predictors of CAD were increased glucose and triglycerides. Abdominal obesity was associated with a lower risk of CAD. In a multivariate logistic regression model for CAD, independent predictors of CAD were age, male gender, glucose and triglycerides. Body mass index had a protective effect. CONCLUSIONS: Although MS is associated with cardiovascular events, the same was not found for stable angiographically proven CAD. Age, gender, diabetes and triglycerides are the most influential factors for CAD, with abdominal obesity as a protective factor.

Published
2012

34. Coronary computed tomography angiography-adapted Leaman score as a tool to noninvasively quantify total coronary atherosclerotic burden

Author

Araújo Gonçalves, P. (Pedro) de, Garcia-Garcia, H.M. (Hector), Dores, H. (Helder), Carvalho, M.S. (Maria Salomé), Jerónimo Sousa, P. (Pedro), Marques, H. (Hugo), Ferreira, A. (Isabel), Cardim, N. (Nuno), Campante Teles, R. (Rui), Raposo, L. (Luís), Mesquita Gabriel, H. (Henrique), Sousa Almeida, M. (Manuel), Aleixo, A. (Ana), Mota Carmo, M. (Miguel), Pereira Machado, F. (Francisco), Mendes, M. (Miguel), Araújo Gonçalves, P. (Pedro) de, Garcia-Garcia, H.M. (Hector), Dores, H. (Helder), Carvalho, M.S. (Maria Salomé), Jerónimo Sousa, P. (Pedro), Marques, H. (Hugo), Ferreira, A. (Isabel), Cardim, N. (Nuno), Campante Teles, R. (Rui), Raposo, L. (Luís), Mesquita Gabriel, H. (Henrique), Sousa Almeida, M. (Manuel), Aleixo, A. (Ana), Mota Carmo, M. (Miguel), Pereira Machado, F. (Francisco), and Mendes, M. (Miguel)

Abstract

To describe a coronary computed tomography angiography (CCTA)-adapted Leaman score (CT-LeSc) as a tool to quantify total coronary atherosclerotic burden with information regarding localization, type of plaque and degree of stenosis and to identify clinical predictors of a high coronary atherosclerotic burden as assessed by the CT-LeSc. Single center prospective registry including a total of 772 consecutive patients undergoing CCTA (Dual-source CT) from April 2011 to March 2012. For the purpose of this study, 581 stable patients referred for suspected coronary artery disease (CAD) without previous myocardial infarction or revascularization procedures were included. Pre-test CAD probability was determined using both the Diamond-Forrester extended CAD consortium method (DF-CAD consortium model) and the Morise score. Cardiovascular risk was assessed with the HeartScore. The cut-off for the 3rd tercile (CT-LeSc ≥8.3) was used to define a population with a high coronary atherosclerotic burden. The median CT-LeSc in this population (n = 581, 8,136 coronary segments evaluated; mean age 57.6 ± 11.1; 55.8 % males; 14.6 % with diabetes) was 2.2 (IQR 0-6.8). In patients with CAD (n = 341), the median CT-LeSc was 5.8 (IQR 3.2-9.6). Among patients with nonobstructive CAD, most were classified in the lowest terciles (T1, 43.0 %; T2, 36.1 %), but 20.9 % were in the highest tercile (T3). The majority of the patients with obstructive CAD were classified in T3 (78.2 %), but 21.8 % had a CT-LeSc in lower terciles (T1 or T2). The independent predictors of a high CT-LeSc were: Male sex (OR 1.73; 95 % CI 1.04-2.90) diabetes (OR 2.91; 95 % CI 1.61-5.23), hypertension (OR 2.54; 95 % CI 1.40-4.63), Morise score ≥16 (OR 1.97; 95 % CI 1.06-3.67) and HeartScore ≥5 (OR 2.42; 95 % CI 1.41-4.14). We described a cardiac CT adapted Leaman score as a tool to quantify total (obstructive and nonobstructive) coronary atherosclerotic burden, reflecting the comprehensive information about localization, de

Published
2013
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36. Poster session V * Saturday 11 December 2010, 08:30-12:30

Author

Pham, Q. H., primary, Von Lueder, T. G., additional, Namtvedt, S. K., additional, Rosjo, H., additional, Omland, T., additional, Steine, K., additional, Timoteo, A. T., additional, Mota Carmo, M., additional, Simoes, M., additional, Branco, L. M., additional, Ferreira, R. C., additional, Kato, R., additional, Ito, J., additional, Tahara, T., additional, Yokoyama, Y., additional, Ashikaga, T., additional, Satoh, Y., additional, Na, J. O., additional, Hong, H. E., additional, Kim, M. N., additional, Shin, S. Y., additional, Choi, C. U., additional, Kim, E. J., additional, Rha, S. W., additional, Park, C. G., additional, Seo, H. S., additional, Oh, D. J., additional, Ticulescu, R., additional, Brigido, S., additional, Vriz, O., additional, Sparacino, L., additional, Popescu, B. A., additional, Ginghina, C., additional, Carerj, S., additional, Nicolosi, G. L., additional, Antonini-Canterin, F., additional, Onaindia Gandarias, J. J., additional, Romero, A., additional, Laraudogoitia, E., additional, Velasco, S., additional, Quintana, O., additional, Cacicedo, A., additional, Rodriguez, I., additional, Alarcon, J. A., additional, Gonzalez, J., additional, Lekuona, I., additional, Subinas, A., additional, Abdula, G., additional, Lund, L. H., additional, Winter, R., additional, Brodin, L., additional, Sahlen, A., additional, Masaki, M., additional, Cha, Y. M., additional, Yuasa, T., additional, Dong, K., additional, Dong, Y. X., additional, Mankad, S. V., additional, Oh, J. K., additional, Vallet, F., additional, Lequeux, B., additional, Diakov, C., additional, Sosner, P., additional, Christiaens, L., additional, Coisne, D., additional, Kihara, C., additional, Murata, K., additional, Wada, Y., additional, Uchida, K., additional, Ueyama, T., additional, Okuda, S., additional, Susa, T., additional, Matsuzaki, M., additional, Cho, E. J., additional, Choi, K. Y., additional, Kwon, B. J., additional, Kim, D. B., additional, Jang, S. W., additional, Cho, J. S., additional, Jung, H. O., additional, Jeon, H. K., additional, Youn, H. J., additional, Kim, J. H., additional, Cikes, M., additional, Bijnens, B., additional, Velagic, V., additional, Kopjar, T., additional, Milicic, D., additional, Biocina, B., additional, Gasparovic, H., additional, Almuntaser, I., additional, Brown, A., additional, Foley, B., additional, Mulvihill, N., additional, Crean, P., additional, King, G., additional, Murphy, R., additional, Takata, Y., additional, Taniguchi, M., additional, Nobusada, S., additional, Sugawara, M., additional, Toh, N., additional, Kusano, K., additional, Itoh, H., additional, Wellnhofer, E., additional, Kriatselis, C., additional, Nedios, S., additional, Gerds-Li, J. H., additional, Fleck, E., additional, Poulsen, M. K., additional, Henriksen, J. E., additional, Dahl, J., additional, Johansen, A., additional, Haghfelt, T., additional, Hoilund-Carlsen, P. F., additional, Beck-Nielsen, H., additional, Moller, J. E., additional, Dankowski, R., additional, Wierzchowiecki, M., additional, Michalski, M., additional, Nowicka, A., additional, Szymanowska, K., additional, Pajak, A., additional, Poprawski, K., additional, Szyszka, A., additional, Kasner, M., additional, Westermann, D., additional, Schultheiss, H. P., additional, Tschoepe, C., additional, Watanabe, T., additional, Iwai-Takano, M., additional, Kobayashi, A., additional, Machii, H., additional, Takeishi, Y., additional, Paelinck, B. P., additional, Van Herck, P. L., additional, Bosmans, J. M., additional, Vrints, C. J., additional, Lamb, H. J., additional, Doltra, A., additional, Vidal, B., additional, Silva, E., additional, Poyatos, S., additional, Mont, L., additional, Berruezo, A., additional, Castel, A., additional, Tolosana, J. M., additional, Brugada, J., additional, Sitges, M., additional, Dencker, M., additional, Bjorgell, O., additional, Hlebowicz, J., additional, Szelenyi, Z. S., additional, Szenasi, G., additional, Kiss, M., additional, Prohaszka, Z., additional, Patocs, A., additional, Karadi, I., additional, Vereckei, A., additional, Saha, S. K., additional, Anderson, P. L., additional, Govind, S., additional, Govindan, M., additional, Moggridge, J. C., additional, Kiotsekoglou, A., additional, Gopal, A. S., additional, Loegstrup, B. B., additional, Christophersen, T. B., additional, Hoefsten, D. E., additional, Moeller, J. E., additional, Boetker, H. E., additional, Egstrup, K., additional, Graefe, M., additional, Huang, F. Q., additional, Zhang, R. S., additional, Le, T. T., additional, Tan, R. S., additional, Sattarzadeh Badkoubeh, R., additional, Tavoosi, A., additional, Elahian, A. R., additional, Drapkina, O., additional, Ivashkin, V. I., additional, Fazakas, A., additional, Pepo, L., additional, Janosi, O., additional, Kopitovic, I., additional, Goncalves, A., additional, Marcos-Alberca, P., additional, Almeria, C., additional, Feltes, G., additional, Rodriguez, E., additional, Garcia, E., additional, Hernandez-Antolin, R., additional, Macaya, C., additional, Silva Cardoso, J., additional, Zamorano, J. L., additional, Navarro, M. S., additional, Valentin, M., additional, Banes, C. M., additional, Rigo, F., additional, Grolla, E., additional, Tona, F., additional, Cuaia, V., additional, Moreo, A., additional, Badano, L., additional, Raviele, A., additional, Iliceto, S., additional, Tarzia, P., additional, Sestito, A., additional, Nerla, R., additional, Di Monaco, A., additional, Infusino, F., additional, Matera, D., additional, Greco, F., additional, Tacchino, R. M., additional, Lanza, G. A., additional, Crea, F., additional, Nemes, A., additional, Balazs, E., additional, Pinter, K. S., additional, Egyed, A., additional, Csanady, M., additional, Forster, T., additional, Holte, E., additional, Vegsundvag, J., additional, Hole, T., additional, Hegbom, K., additional, Wiseth, R., additional, Sharif, D., additional, Sharif-Rasslan, A., additional, Shahla, C., additional, Khalil, A., additional, Rosenschein, U., additional, Zagatina, A., additional, Zhuravskaya, N., additional, Tyurina, T. V., additional, Tagliamonte, E., additional, Cirillo, T., additional, Coppola, A., additional, Marinelli, U., additional, Romano, C., additional, Riccio, G., additional, Citro, R., additional, Astarita, C., additional, Capuano, N., additional, Quaranta, G., additional, Desiderio, A., additional, Frattini, S., additional, Faggiano, P., additional, Zilioli, V., additional, Locantore, E., additional, Longhi, S., additional, Bellandi, F., additional, Faden, G., additional, Triggiani, M., additional, Dei Cas, L., additional, Dalsgaard, M., additional, Kjaergaard, J., additional, Iversen, K., additional, Hassager, C., additional, Dinh, W., additional, Nickl, W. N., additional, Smettan, J. S., additional, Koehler, T. K., additional, Scheffold, T. D., additional, Coll Barroso, M. C. B., additional, Guelker, J. G., additional, Fueth, R. F., additional, Kamperidis, V., additional, Hadjimiltiades, S., additional, Sianos, G., additional, Efthimiadis, G., additional, Karvounis, H., additional, Parcharidis, G., additional, Styliadis, I. H., additional, Velasco Del Castillo, M. S., additional, Onaindia, J. J., additional, Telleria, M., additional, Carstensen, H. G., additional, Nordenberg, C., additional, Sogaard, P., additional, Fritz-Hansen, T., additional, Bech, J., additional, Galatius, S., additional, Jensen, J. S., additional, Mogelvang, R., additional, Bartko, P. E., additional, Graf, S., additional, Rosenhek, R., additional, Burwash, I. G., additional, Bergler-Klein, J., additional, Clavel, M.-A., additional, Baumgartner, H., additional, Pibarot, P., additional, Mundigler, G., additional, Kirilmaz, B., additional, Eser, I., additional, Tuzun, N., additional, Komur, B., additional, Dogan, H., additional, Taskiran Comez, A., additional, Ercan, E., additional, Cusma-Piccione, M., additional, Zito, C., additional, Oreto, G., additional, Piluso, S., additional, Tripepi, S., additional, Oreto, L., additional, Longordo, C., additional, Ciraci, L., additional, Di Bella, G., additional, Piatkowski, R., additional, Kochanowski, J., additional, Scislo, P., additional, Grabowski, M., additional, Marchel, M., additional, Roik, M., additional, Kosior, D., additional, Opolski, G., additional, Sknouril, L., additional, Dorda, M., additional, Holek, B., additional, Gajdusek, L., additional, Chovancik, J., additional, Branny, M., additional, Fiala, M., additional, Szymanski, P., additional, Lipczynska, M., additional, Klisiewicz, A., additional, Hoffman, P., additional, Jander, N., additional, Minners, J., additional, Martin, G., additional, Zeh, W., additional, Allgeier, M., additional, Gohlke-Baewolf, C., additional, Gohlke, H., additional, Nistri, S., additional, Porciani, M. C., additional, Attanasio, M., additional, Abbate, R., additional, Gensini, G. F., additional, Pepe, G., additional, Duncan, R. F., additional, Piantadosi, C., additional, Nelson, A. J., additional, Wittert, G., additional, Dundon, B., additional, Worthley, M. I., additional, Worthley, S. G., additional, Jung, P., additional, Berlinger, K., additional, Rieber, J., additional, Sohn, H. Z., additional, Schneider, P., additional, Leibig, M., additional, Koenig, A., additional, Klauss, V., additional, Tomkiewicz-Pajak, L., additional, Kolcz, J., additional, Olszowska, M., additional, Pieculewicz, M., additional, Podolec, P., additional, Przewlocki, T., additional, Suchon, E., additional, Sobien, B., additional, Wilkolek, P., additional, Ziembicka, A., additional, Hlawaty, M., additional, Van De Bruaene, A., additional, Hermans, H., additional, Buys, R., additional, Vanhees, L., additional, Delcroix, M., additional, Voigt, J.-U., additional, Budts, W., additional, De Cillis, E., additional, Acquaviva, T., additional, Basile, D., additional, Bortone, A. S., additional, Kalimanovska-Ostric, D., additional, Nastasovic, T., additional, Vujisic-Tesic, B., additional, Jovanovic, I., additional, Milakovic, B., additional, Dostanic, M., additional, Stosic, M., additional, Frogoudaki, A., additional, Andreou, K., additional, Parisis, J., additional, Triantafyllidi, E., additional, Gaitani, S., additional, Paraskevaidis, J., additional, Anastasiou-Nana, M., additional, De Pasquale, G., additional, Kuehn, A., additional, Petzuch, K., additional, Mueller, J., additional, Meierhofer, C., additional, Fratz, S., additional, Hager, A., additional, Hess, J., additional, Vogt, M., additional, Attenhofer Jost, C. H., additional, Dearani, J. A., additional, Scott, C. G., additional, Burkhart, H. M., additional, Connolly, H. M., additional, Vitarelli, A., additional, Battaglia, D., additional, Caranci, F., additional, Padella, V., additional, Continanza, G., additional, Dettori, O., additional, Capotosto, L., additional, Vitarelli, M., additional, De Cicco, V., additional, Cortez Morichetti, M., additional, Mohanan Nair, K. K., additional, Sasidaharan, B., additional, Thajudeen, A., additional, Tharakan, J. M., additional, Mertens, L., additional, Ahmad, N., additional, Kantor, P. K., additional, Grosse-Wortmann, L., additional, Friedberg, M. K., additional, Bernard, Y. F., additional, Morel, M. A., additional, Descotes-Genon, V., additional, Jehl, J., additional, Meneveau, N., additional, Schiele, F., additional, Kaldararova, M., additional, Simkova, I., additional, Tittel, P., additional, Masura, J., additional, Trojnarska, O., additional, Szczepaniak, L., additional, Mizia -Stec, K., additional, Cieplucha, A., additional, Bartczak, A., additional, Grajek, S., additional, Tykarski, A., additional, Gasior, Z., additional, Babovicvuksanovic, D., additional, Bonnichsen, C. R., additional, Morgan, G. J., additional, Slorach, C., additional, Hui, W., additional, Sarkola, T., additional, Lee, K. J., additional, Chaturvedi, R., additional, Benson, L., additional, Bradley, T., additional, Iancu, M. E., additional, Ghiorghiu, I., additional, Serban, M., additional, Craciunescu, I., additional, Hodo, A., additional, Morgan, J., additional, Roche, L., additional, Lee, K., additional, Milanesi, O., additional, Favero, V., additional, Padalino, M., additional, Biffanti, R., additional, Cerutti, A., additional, Maschietto, N., additional, Reffo, E., additional, Vida, V., additional, Stellin, G., additional, Irtyuga, O., additional, Gamazin, D., additional, Voronkina, I., additional, Tsoyi, N., additional, Gudkova, E., additional, Moiseeva, O., additional, Aggeli, C., additional, Kazazaki, C., additional, Felekos, I., additional, Lagoudakou, S., additional, Roussakis, G., additional, Skoumas, J., additional, Pitsavos, C., additional, Stefanadis, C., additional, Cueff, C., additional, Keenan, N., additional, Steg, P. G., additional, Cimadevilla, C., additional, Ducrocq, G., additional, Vahanian, A., additional, Messika-Zeitoun, D., additional, Petrella, L., additional, Mazzola, A. M., additional, Villani, C. V., additional, Giancola, R. G., additional, Ciocca, M. C., additional, Di Eusanio, D. E. M., additional, Nolan, S., additional, Ionescu, A., additional, Skaug, T. R., additional, Amundsen, B. H., additional, Hergum, T., additional, Torp, H., additional, Haugen, B. O., additional, Lopez Aguilera, J., additional, Mesa Rubio, D., additional, Ruiz Ortiz, M., additional, Delgado Ortega, M., additional, Villanueva Fernandez, E., additional, Cejudo Diaz Del Campo, L., additional, Toledano Delgado, F., additional, Leon Del Pino, M., additional, Romo Pena, E., additional, Suarez De Lezo Cruz-Conde, J., additional, De Marco, E., additional, Colucci, A., additional, Comerci, G., additional, Gabrielli, F. A., additional, Natali, R., additional, Garramone, B., additional, Savino, M., additional, Lotrionte, M., additional, Sonaglioni, A., additional, Loperfido, F., additional, Zdravkovic, M., additional, Perunicic, J., additional, Krotin, M., additional, Ristic, M., additional, Vukomanovic, V., additional, Zaja, M., additional, Radovanovic, S., additional, Saric, J., additional, Zdravkovic, D., additional, Cotrim, C., additional, Almeida, A. R., additional, Miranda, R., additional, Almeida, A. G., additional, Picano, E., additional, Carrageta, M., additional, D'andrea, A., additional, Cocchia, R., additional, Riegler, L., additional, Golia, E., additional, Scarafile, R., additional, Caso, P., additional, Russo, M. G., additional, Bossone, E., additional, Calabro', R., additional, Noman, H., additional, Adel, A., additional, Elfaramawy, A. M. R., additional, Abdelraouf, M., additional, Elnaggar, W. A. E. L., additional, Baligh, E., additional, Sargento, L., additional, Silva, D., additional, Goncalves, S., additional, Ribeiro, S., additional, Vinhas Sousa, G., additional, Almeida, A., additional, Lopes, M., additional, Rodriguez-Manero, M., additional, Aguado Gil, L., additional, Azcarate, P., additional, Lloret Luna, P., additional, Macias Gallego, A., additional, Castano, S. A. R. A., additional, Garcia, M., additional, Pujol Salvador, C., additional, Barba, J., additional, Redondo, P., additional, Tomasoni, L., additional, Sitia, S., additional, Atzeni, F., additional, Gianturco, L., additional, Ricci, C., additional, Sarzi-Puttini, P., additional, Turiel, M., additional, De Gennaro Colonna, V., additional, Uejima, T., additional, Jaroch, J., additional, Polombo, C., additional, Hughes, A., additional, Vinereanu, D., additional, Evanvelista, A., additional, Leftheriotis, G., additional, Fraser, A. G., additional, Lewczuk, A., additional, Sobkowicz, B., additional, Tomaszuk-Kazberuk, A., additional, Sawicki, R., additional, Hirnle, T., additional, Michalski, B. W., additional, Filipiak, D., additional, Kasprzak, J. D., additional, Lipiec, P., additional, Dalen, H., additional, Mjolstad, O. C., additional, Klykken, B. E., additional, Graven, T., additional, Martensson, M., additional, Olsson, M., additional, Brodin, L.-A., additional, Enache, R., additional, Leiballi, E., additional, Penhall, A., additional, Perry, R., additional, Altman, M., additional, Sinhal, A., additional, Bennetts, J., additional, Chew, D. P., additional, Joseph, M. X., additional, Larsen, L. H., additional, Kristensen, T., additional, Kober, L. V., additional, Kofoed, K. F., additional, Moscoso Costa, F., additional, Ribeiras, R., additional, Brito, J., additional, Boshoff, S., additional, Neves, J., additional, Teles, R., additional, Canada, M., additional, Andrade, M. J., additional, Gouveia, R., additional, Silva, A., additional, Miskovic, A., additional, Poerner, T. P., additional, Stiller, C. S., additional, Goebel, B. G., additional, Moritz, A. M., additional, Stefani, L., additional, Galanti, G. G., additional, Moraldo, M., additional, Bergamini, C., additional, Pabari, P. A., additional, Dhutia, N. M., additional, Malaweera, A. S. N., additional, Willson, K., additional, Davies, J., additional, Hughes, A. D., additional, Xu, X. Y., additional, Francis, D. P., additional, Jasaityte, R., additional, Amundsen, B., additional, Barbosa, D., additional, Loeckx, D., additional, Kiss, G., additional, Orderud, F., additional, Robesyn, V., additional, Claus, P., additional, D'hooge, J., additional, Nao, T., additional, Miura, T., additional, Shams, K., additional, Samir, S., additional, Samir, R., additional, El-Sayed, M., additional, Anwar, A. M., additional, Nosir, Y., additional, Galal, A., additional, Chamsi-Pasha, H., additional, Ciobanu, A., additional, Dulgheru, R., additional, Bennett, S., additional, De Luca, A., additional, Toncelli, L., additional, Cappelli, F., additional, Cappelli, B., additional, Vono, M. C. R., additional, Galanti, G., additional, Zorman, Y., additional, Yilmazer, M. S., additional, Akyildiz, M., additional, Gurol, T., additional, Aydin, A., additional, Dagdeviren, B., additional, and Kalangos, A., additional

Published
2010
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47. Rapid Fire Abstract session: usefulness of CT and radionuclide imaging in different clinical scenarios

Author

Lagan, J, Meah, M, Hasleton, J, Mcshane, J, Trent, R, Rio, P, Abreu, A, Santos, V, Santa-Clara, H, Oliveira, L, Martins Oliveira, M, Silva Cunha, P, Moura Branco, L, Mota Carmo, M, Cruz Ferreira, R, Barone-Rochette, G, Zoreka, FZ, Calizzano, A, Vautrin, E, Quesada, JL, Broisat, A, Riou, L, Baguet, JP, Fagret, D, Ghezzi, C, Limeres Freire, J, Rodriguez, J, Oristrell, G, Quiroga, X, Pizzi, N, Perez-Rodon, J, Galve, E, Aguade, S, Abreu, A, Santa Clara, H, Santos, V, Oliveira, L, Oliveira, M, Rio, P, Cunha, P, Portugal, G, Ferreira, R, Mota Carmo, M, BETTER-HF, Clerc, O F, Kaufmann, B P, Possner, M, Liga, R, Vontobel, J, Mikulicic, F, Graeni, C, Benz, D C, Kaufmann, P A, Buechel, R R, Iriart, X, Selmi, W, Jalal, Z, Thambo, JB, Van Den Hoven, AT, Saru-Chelu, RG, Duijnhouwer, AL, Van Hagen, IM, and Roos-Hesselink, JW

Abstract

Purpose: The National Institute for Health and Care Excellence (NICE) and the European Society of Cardiology (ESC) support the use of different cardiac imaging modalities in patients with suspected ischaemic heart disease (IHD). The cost of single photon emission computed tomography (SPECT) and invasive coronary angiography (ICA) in UK is estimated at £293 and £1052 respectively. Following positive SPECT, a large number of patients at our institution progressed to ICA which did not confirm significant coronary artery disease. As a result, a new SPECT scanner was acquired with ECG gating and in-built CT to correct for diaphragm / breast attenuation. Methods: We calculated cumulative cost of SPECT +/- ICA per patient before and after the scanner change. We screened patients with fixed / no defects on SPECT for acute coronary syndromes and cardiac related deaths in one year after the scan. Results: See Table 1. The new scanner detected significantly more fixed perfusion defects (p=0.0007, Fisher's exact test) and less reversible defects necessitating progression to ICA (p=0.001, Chi-square test). The cost of SPECT +/- ICA per patient was £713.8 in the old scanner group (£57,104 in total) and £468.3 in the new scanner group (£44,460 in total). Patients with normal SPECT or fixed defects did not have cardiac related deaths or acute coronary syndromes during following 12 months. Conclusions: The new scanner allowed for significant cost savings in our institution reducing the cost of SPECT +/- ICA from £713.8 to £468.3 per patient without compromising patients' safety. This is crucial in current climate of financial austerity. Our study was limited by the small number of patients and by the fact that many patients with reversible ischaemia were not referred for ICA due to different reasons: minor symptoms / ischaemia on SPECT (n=15), patients not attending follow up (n=3), non cardiac death (n=1), other imaging modalities chosen (n=2). Old ScannerNew ScannerNumber of SPECT8096Reversible defect on SPECT42 (52.5%)27 (28.1%)Fixed defect on SPECT3 (3.75%)20 (20.8%)Number of ICA32 (40%)16 (16.7%)Cost of SPECT +/- ICA per patient£713.8£468.3 SPECT/ICA results

Published
2015
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48. Poster session 2

Author

Martins Fernandes, S, Teixeira, R, Roussin, I, Lynch, M, Badano, L, Muraru, D, Romeo, G, Ermacora, D, Marotta, C, Aruta, P, Cucchini, U, Iliceto, S, Garcia Campos, A, Martin-Fernandez, M, De La Hera Galarza, JM, Corros-Vicente, C, Colunga Blanco, S, Velasco-Alonso, E, Leon-Aguero, V, Rodriguez-Suarez, ML, Moris De La Tassa, C, Erdei, T, Edwards, J, Braim, D, Price, C, Fraser, AG, Cardiff, Investigators, MEDIA, Mehdipoor, G, Salmani, F, Arjmand Shabestari, A, Hanboly, N, Michalski, BW, Szymczyk, E, Kupczynska, K, Peczek, L, Nawrot, B, Lipiec, P, Kasprzak, JD, Vriz, O, Driussi, C, Ferrara, F, Brosolo, G, Antonini-Canterin, F, Magne, J, Aboyans, V, Bossone, E, Mo, VY, Bellucci, BM, Fisher, JM, Balekian, AA, Le, T T, Idapalapati, S, Huang, F, Wong, JI, Tan, RS, Ribeiro, JM, Teixeira, R, Madeira, M, Almeida, I, Reis, L, Siserman, A, Dinis, P, Dias, L, Ramos, AP, Goncalves, L, Ternacle, J, Wan, FW, Sawaki, DS, Dubois-Rande, JLDR, Adnot, SA, Czibik, GC, Derumeaux, GD, Yurdakul, SELEN, Ercan, G, Tekkesin, ILKER, Sahin, ST, Cengiz, B, Celik, G, Demircan, S, Aytekin, SAIDE, Shetye, A, Razvi, NA, Nazir, SA, Price, N, Khan, JN, Kanagala, P, Singh, A, Squire, I, Mccann, GP, Stoebe, S, Langel, M, Pfeiffer, D, Hagendorff, A, Lisowska, A, Ptaszynska-Kopczynska, K, Marcinkiewicz-Siemion, M, Knapp, M, Witkowski, M, Musial, WJ, Kaminski, K, Chinali, M, Natali, B, D' Anna, C, Leonardi, B, Secinaro, A, Pongiglione, G, Rinelli, G, Orabona, M, Renard, S, Michel, N, Mancini, J, Haentjens, J, Sitbon, O, Habib, G, Contaldi, C, Imbriaco, M, Alcidi, G, Santoro, C, Buonauro, A, Lo Iudice, F, Lembo, M, Cuocolo, A, Trimarco, B, Galderisi, M, De La Chica, JA, Mora Robles, J, Roldan Jimenez, MA, Mancisidor, MA, De Mora, MA, Codolosa, JN, Alnabelsi, T, Goykhman, I, Koshkelashvili, N, Romero-Corral, A, Pressman, GS, Trzcinski, P, Michalski, BW, Kupczynska, K, Miskowiec, D, Lipiec, P, Kasprzak, JD, Prado Diaz, S, Montoro Lopez, N, Refoyo Salicio, E, Valbuena Lopez, SC, Gonzalez, O, Alvarez, C, Moreno Yanguela, M, Bartha Rasero, JL, De La Calle, M, Guzman Martinez, G, Morales Portano, J D, Suarez-Cuenca, JA, Merino, JA, Gomez Alvarez, E B, Delgado, LG, Ha, SJ, Woo, YM, Bang, WD, Sohn, GH, Cheong, SS, Yoo, SY, Valente, F, Rodriguez Palomares, JF, Gutierrez, L, Maldonado, G, Pineda, V, Galian, L, Teixido, G, Gonzalez Allujas, MT, Evangelista, A, Garcia Dorado, D, Joseph, G, Zaremba, T, Ekeloef, S, Heiberg, E, Engblom, H, Jensen, SE, Sogaard, P, Valente, F, Rodriguez Palomares, JF, Gutierrez, L, Garcia, G, Pineda, V, Galian, L, Teixido, G, Gonzalez Allujas, MT, Evangelista, A, Garcia Dorado, D, Scali, MC, Dini, FL, Galli, F, Lattanzi, F, Picano, E, Marzilli, M, Cordeiro, F, Leao, S, Moz, M, Magalhaes, P, Trigo, J, Mateus, PS, Ferreira, A, Moreira, JI, Duchateau, N, De Craene, M, Legallois, D, Labombarda, F, Pellissier, A, Sermesant, M, Saloux, E, Fabris, E, Merlo, M, Moretti, M, Barbati, G, Stolfo, D, Gigli, M, Pinamonti, B, Sinagra, G, Costantino, MF, Dores, E, Matera, A, Innelli, P, Innelli, P, Lopizzo, A, Violini, R, Fiorilli, R, Cappabianca, G, Picano, E, Tarsia, G, Cho, I J, Seo, J, Chang, HJ, Heo, R, Kim, IC, Shim, CY, Hong, GR, Chung, N, Goublaire, C, Melissopoulou, MM, Nguyen, V, Brochet, E, Cimadevilla, C, Codogno, I, Vahanian, A, Messika-Zeitoun, D, Lam, W, Pontana, F, Vassiliou, V, Prasad, S, Galli, E, Leclercq, C, Samset, E, Donal, E, Kim, KH, Lim, DS, Mariani, M, Bianchi, G, Rossi, F, Gianetti, J, Marchi, F, Cerone, E, Nardelli, A, Terrazzi, M, Solinas, M, Maffei, S, Malev, E, Pshepiy, A, Vasina, L, Timofeev, E, Reeva, S, Zemtsovsky, E, Zuercher, F, Brugger, N, Jahren, S, De Marchi, SF, Seiler, C, Tang, Z, Jin, CN, Tang, H, Fan, K, Kam, K, Yan, BP, Yu, CM, Lee, PW, Cimino, S, Reali, M, Silvetti, E, Salatino, T, Mancone, M, Pennacchi, M, Giordano, A, Sardella, G, Agati, L, Mahia, P, Tirado, G, Nogales-Romo, MT, Marcos-Alberca, P, De Agustin, A, Almeria, C, Rodrigo, JL, Garcia Fernandez, MA, Macaya, C, Perez De Isla, L, De La Chica, JA, Mancisidor, M, Lara Garcia, C, Vivancos, R, De Mora, M, Petrovic, J, Petrovic, M, Vujisic-Tesic, B, Trifunovic, D, Boricic-Kostic, M, Petrovic, I, Draganic, G, Petrovic, O, Tomic-Dragovic, M, Ciobotaru, V, Remsey- Semmelweiss, E, Kogoj, P, Furlan, T, Ambrozic, J, Mohorko Pleskovic, PN, Bunc, M, Guerreiro, S, Ribeiras, R, Abecasis, J, Andrade, MJ, Mendes, M, Saxena, A, Ramakrishnan, S, Gupta, SK, Juneja, R, Kothari, SS, Mozenska, O, Zaleska, M, Segiet, A, Chwesiuk, S, Kroc, A, Kosior, DA, Pontone, G, Andreini, D, Solbiati, A, Guglielmo, M, Mushtaq, S, Baggiano, A, Beltrama, V, Rota, C, Guaricci, AI, Pepi, M, Macaya Ten, F, Pons Llinares, J, Asmarats Serra, L, Pericas Ramis, P, Caldes Llull, O, Grau Sepulveda, A, Frontera, G, Vaquer Segui, A, Noris, M, Bethencourt Gonzalez, A, Caballero, L, Climent Paya, V, Martinez Moreno, M, Saura, D, Oliva, MJ, Sanchez Quinones, J, Garcia Honrubia, A, Valdes, M, De La Morena, G, Avegliano, G, Terricabras, M, Costabel, JP, Ronderos, R, Evangelista, A, Venturini, C, Galve, E, Halmai, L, Nemes, A, Neubauer, S, Rahman Haley, S, Banner, N, Reis, L, Teixeira, R, Caetano, F, Almeida, I, Trigo, J, Botelho, A, Silva, J, Nascimento, J, Goncalves, L, Trifunovic, D, Tesic, M, Jovanovic, I, Petrovic, O, Boricic-Kostic, M, Dragovic, M, Petrovic, M, Stepanovic, J, Banovic, M, Vujisic-Tesic, B, Gospodinova, M, Guergelcheva, V, Chamova, T, Sarafov, S, Tournev, I, Denchev, S, Makavos, G, Ikonomidis, I, Psarogiannakopoulos, P, Tsirigotis, P, Paraskevaidis, I, Lekakis, J, D'ascenzi, F, Pelliccia, A, Natali, BM, Cameli, M, Focardi, M, Bonifazi, M, Mondillo, S, Dantas Tavares De Melo, M, Lima, C, Assed, L, Kalil Filho, R, Mady, C, Bochi, E A, Salemi, V M C, Bonapace, S, Targher, G, Valbusa, F, Rossi, A, Lanzoni, L, Lipari, P, Zenari, L, Molon, G, Canali, G, Barbieri, E, Kulkarni, A, Li, L, Craft, M, Nanda, M, Lorenzo, JM, Kutty, S, Cameli, M, Bombardini, T, Sparla, S, Di Tommaso, C, Losito, M, Incampo, E, Maccherini, M, Mondillo, S, Ingvarsson, A, Werther Evaldsson, A, Radegran, G, Stagmo, M, Waktare, J, Roijer, A, Meurling, CJ, Driessen, MMP, Hui, W, Meijboom, FJ, Bijnens, B, Dragulescu, A, Mertens, L, Friedberg, MK, Tufekcioglu, O, Sensoy, B, Suleymanoglu, M, Akin, Y, Sahan, E, Sasmaz, H, Radulescu, D, Pasca, L, Buzdugan, E, Chis, B, Stoicescu, L, Barac, A, Lynce, FC, Smith, KL, Mete, M, Isaacs, C, Cioffi, G, Viapiana, O, Di Nora, C, Ognibeni, F, Fracassi, E, Giollo, A, Mazzone, C, Faganello, G, Di Lenarda, A, Rossini, M, Almeida Morais, L, Galrinho, A, Branco, L, Timoteo, A T, Rodrigues, I, Daniel, P, Rosa, S, Ferreira, L, Ferreira, R, Ledakowicz-Polak, A, Polak, L, Krauza, G, Stokfisz, K, Zielinska, M, Portugal, G, Branco, L M, Galrinho, A, Mota Carmo, M, Teresa Timoteo, A, Aguiar Rosa, S, Abreu, J, Pinto Teixeira, P, Viveiros Monteiro, A, Cruz Ferreira, R, Naksuk, N, Peeraphatdit, T, Chaiteerakij, R, Klarich, KW, Parato, V M, Masia, S, Kovalova, S, Necas, J, Cherubini, A, Nistri, S, Negri, F, Barbati, G, Cioffi, G, Russo, G, Mazzone, C, Faganello, G, Pandullo, C, Di Lenarda, A, Corrado, G, Durante, A, Rovelli, E, Genchi, V, Trabattoni, L, Zerboni, SC, Cattaneo, L, Butti, E, Ferrari, G, Malev, E, Luneva, E, Mitrofanova, L, Uspensky, V, Zemtsovsky, E, Wierzbowska-Drabik, K, Kasprzak, JD, Lesevic, H, Rosner, S, Karl, M, Ott, I, Sonne, C, Laredj, N, Ali Lahmar, HM, Hammou, L, Pieles, G E, Forsey, J, Gowing, L, Miller, F, Ramanujam, P, Stuart, AG, Williams, CA, Generati, G, Bandera, F, Pellegrino, M, Carbone, F, Labate, V, Alfonzetti, E, Guazzi, M, Van Zalen, JJ, Patel, NR, Raju, P, Beale, L, Brickley, G, Lloyd, GW, Aquila, I, Fernandez-Golfin, C, Gonzalez, A, Rincon, LM, Hinojar, R, Garcia, A, Megias, A, Jimenez-Nacher, JJ, Moya, JL, Zamorano, JL, Cheng, H-L, Lanzoni, L, Molon, G, Canali, G, Bonapace, S, Chiampan, A, Albrigi, L, Barbieri, E, Asmarats Serra, L, Noris Mora, M, Rodriguez Fernandez, A, Exposito Pineda, C, Grande, C, Gonzalez Colino, R, Macaya Ten, F, Fernandez Vazquez, X, Fortuny Frau, E, Bethencourt Gonzalez, A, Kadrabulatova, S, Ranjbar, S, Karvandi, M, Szczesniak-Stanczyk, D, Blaszczyk, R, Zarczuk, R, Brzozowski, W, Janowski, M, Wysokinski, A, Stanczyk, B, Consortium, ReMeDi, Sharka, I, Myftiu, S, Teferici, D, Quka, A, Dado, E, Djamandi, J, Kresto, L, Duka, A, Kristo, A, Balla, I, Di Salvo, G, Issa, Z, Moiduddin, N, Siblini, G, Bulbul, Z, Ben Kahla, S, Abid, L, Abid, D, Kammoun, S, Li, L, Rush, E, Craft, M, Goodwin, J, Kreikemeier, R, Cantinotti, M, Kutty, S, Hadeed, HA, Zolaly, M A, Khoshhal, SQ, El-Harbi, K, Tarawah, A, Al-Hawsawi, Z, Al-Mozainy, I, Habeeb, H A, Bakhoum, S W G, Nabil, M N, Elebrashy, I N, Toscano, A, Chinali, M, Albanese, S, Carotti, A, Iacobelli, R, Esposito, C, Secinaro, A, Moscogiuri, G, Pasquini, L, Granata, F, Malvezzi Caracciolo, M, Bianchi, RM, Caso, P, Arenga, F, Riegler, L, Scarafile, R, D'andrea, A, Russo, MG, Calabro', P, Djikic, D, Simic, DS, Peric, VP, Mujovic, NM, Marinkovic, MM, Jankovic, NJ, Wdowiak-Okrojek, K, Shim, A, Wejner-Mik, P, Kasprzak, JD, Lipiec, P, Girgis, H Y A, Sharma, A, Jain, N, Kharwar, R, Saran, RK, Narain, VS, Dwivedi, SK, Sethi, R, Chandra, S, Pradhan, A, Safal, S, Soro, C, Marchetti, MF, Cacace, C, Congia, M, Nissardi, V, Ruscazio, M, Meloni, L, Montisci, R, Gallego Page, J C, Gallego Sanchez, G, Calero, S, Portero, JJ, Tercero, A, Garcia, JC, Barambio, M, Martinez Lazaro, R, Corneli, M, Meretta, AH, Perea, GO, Belcastro, F, Aguirre, E, De Luca, I, Henquin, R, and Masoli, O

Abstract

Introduction: The relationship between the appropriateness of the transthoracic echocardiography (TTE) and its clinical impact is still a matter of debate. Objective: The aim of this study was to assess the degree of adherence to the appropriate use criteria for echocardiography, in a tertiary public hospital in the United Kingdom, as well as the clinical impact of the exam on patient management. Methods: 859 TTE’s performed consecutively during January 2014 were reviewed to assess its appropriateness, and were classified as appropriate, uncertain or inappropriate using the 2011 guidelines. Subsequently, patient’s files were examined to determine the clinical impact of the TTE which was assigned to one of the following three categories: (1) active change in care, (2) continuation of current care, or (3) no change in care. Patients which files were not available were excluded (259). All classifications were evaluated by two independent cardiologists, with no direct relation to the study. Results: Our sample had a mean age of 63 ± 17 years with a gender balance. The majority of the exams were requested at the outpatient (81.4%) clinic, by cardiologists (50.3%) and general practitioners (13.4%). Regarding the main findings, in 7.6% of the studies there were moderate to severe systolic dysfunction; 4.0% showed severe valvular heart disease and 5.1% had significant pulmonary hypertension. Relatively to the appropriateness of the TTE requests, 76.5% were considered appropriate, 7.1% inappropriate and 12.6% uncertain. With respect to the clinical impact of the TTE’s, 42.7% of the exams led to an active change in care, 15.6% to a continuation of the care and 11.5% revealed no change in care. Age (β0.90, P=0.05) and outpatient setting (β4.4, P<0.01) were the most important predictors of an active change of care exam. On the contrary, the appropriateness of the TTE’s requests (β1.1, P=0.56) and the specialist ordering the exams (β0.81, P=0.26) were not independently associated. Conclusion: Our data showed that almost 8 out of 10 TTE were considered appropriate, and 4 out of 10 exams had an active clinical impact.

Published
2015
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49. Poster session 1

Author

Haberka, M, Banska, K, Gasior, Z, Garcia Martin, A, Moya-Mur, JL, Carbonell-San Roman, S-A, Rodriguez-Munoz, D, Garcia-Lledo, A, Casas-Rojo, E, Hinojar, R, Jimenez-Nacher, JJ, Fernandez-Golfin, C, Zamorano-Gomez, JL, Barbier, P, Ravani, A, Cefalu, C, Maltagliati, A, Frigerio, B, Sansaro, D, Amato, M, Baldassarre, D, Pellegrino, M, Bandera, F, Generati, G, Labate, V, Alfonzetti, E, Guazzi, M, Angelis, A, Aggeli, K, Ioakeimidis, N, Abdelrasoul, M, Felekos, I, Gourgouli, I, Aznaouridis, K, Rousakis, G, Vlachopoulos, C, Tousoulis, D, Howlett, PJ, Darasz, K, Mahmoudi, M, Shah, N, Jabr, RI, Hickman, M, Leatham, EW, Fry, CH, PREDICT-PAF, Madeira, M, Teixeira, R, Almeida, I, Caetano, F, Fernandes, A, Cassandra, M, Reis, L, Costa, M, Goncalves, L, Carrero, PJ, Nielsen, AJ, Carrero, MC, Saubidet, GL, Peralta, SP, Argentina, Aorta Abdominal, Hansen, KL, Moeller-Soerensen, H, Kjaergaard, J, Jensen, MB, Lund, JT, Pedersen, MM, Olesen, JB, Jensen, JA, Nielsen, MB, Trunina, I, Sharykin, AS, Karelina, EV, Telezhnikova, ND, Basar, C, Ozhan, H, Kayapinar, O, Albayrak, ES, Lie, OH, Saberniak, J, Dejgaard, L, Nestaas, E, Edvardsen, T, Haugaa, KH, Sade, LE, Bal, U, Eroglu, S, Pirat, B, Muderrisoglu, H, Gopal, A S, Muthukumar, L, Saha, SK, Toole, RS, Klug, G, Reinstadler, S, Feistritzer, HJ, Pernter, B, Mayr, A, Franz, WM, Mueller, S, Metzler, B, Rodriguez Gonzalez, E, Mingo Santos, S, Palomero Monivas, V, Gonzalez Mirelis, J, Goirigolzarri Artaza, J, Zorita Gil, B, Fernandez Diaz, JA, Goicolea Ruigomez, J, Restrepo Cordoba, MA, Alonso Pulpon, L, Ferrara, F, Gargani, L, D'alto, M, Ghio, S, Acri, E, Carannante, L, Argiento, P, D'andrea, A, Vriz, O, Bossone, E, Moustafa, S, Ho, TH, Shah, P, Murphy, K, Nelluri, BK, Lee, H, Wilansky, S, Mookadam, F, Naksuk, N, Peeraphatdit, T, Chaiteerakij, R, Klarich, KW, Cantinotti, M, Scalese, M, Melo, M, Assanta, N, Marotta, M, Crocetti, M, Spadoni, I, Giordano, R, Kutty, S, Iervasi, I, Michelsen, MM, Mygind, ND, Pena, A, Frestad, D, Hoest, N, Prescott, E, Fernandes, JMG, Romao, BO, Rivera, IR, Mendonca, MA, Carvalho, AC, Campos, O, Amato, A, Moises, VA, Demir, OM, Bashir, A, Marshall, K, Douglas, M, Wasan, B, Plein, S, Alfakih, K, Cano Carrizal, R, Casanova Rodriguez, C, Cadenas Chamorro, R, Iglesias Del Valle, D, Martin-Penato Molina, A, De Juan Baguda, J, Prieto Moriche, E, Garcia Garcia, A, De La Cruz Berlanga, E, Plaza Perez, I, Bouzas-Mosquera, A, Peteiro, J, Broullon, FJ, Alvarez-Garcia, N, Barbeito-Caamano, C, Larranaga-Moreira, JM, Maneiro-Melon, N, Martinez-Ruiz, D, Yanez, JC, Vazquez-Rodriguez, JM, Leao, S, Cordeiro, F, Magalhaes, P, Moz, M, Trigo, J, Mateus, P, Fontes, P, Moreira, I, Kuznetsov, VA, Krinochkin, DV, Plusnin, AV, Soldatova, AM, Nazir, S A, Shetye, A, Khan, JN, Singh, A, Kanagala, P, Swarbrick, DJ, Graham-Brown, M, Mccann, GP, Trifunovic, D, Krljanac, G, Savic, L, Asanin, M, Aleksandric, S, Lasica, R, Srdic, M, Zlatic, N, Petrovic, M, Mrdovic, I, Rodriguez Gonzalez, E, Mingo Santos, S, Monivas Palomero, V, Gonzalez Mirelis, J, Zorita Gil, B, Fernandez Diaz, JA, Restrepo Cordoba, MA, Goirigolzarri Artaza, J, Rivero Arribas, B, Goicolea Ruigomez, J, Spampinato, RA, Dobrovie, M, Da Rocha E Silva, JG, Bonamigo Thome, F, Kluttig, R, Schloma, V, Dmitrieva, Y, Strotdrees, E, Mohr, FW, Antonini-Canterin, F, Luzza, G, Caruso, R, Belfiore, R, Della Mattia, A, Poli, S, Vriz, O, Zito, C, La Carrubba, S, Carerj, S, Ribeiro, JM, Teixeira, R, Goncalves, L, Morgado, GJ, Carvalho, JF, Gomes, AC, Caldeira, D, Cruz, IR, Stuart, B, Maia, R, Fazendas, P, Pereira, H, Trifunovic, D, Rakocevic, I, Tutos, V, Petrovic, O, Petrovic, M, Boricic-Kostic, M, Stepanovic, J, Jovanovic, I, Banovic, M, Vujisic-Tesic, B, Reis, L, Teixeira, R, Leite, L, Fernandes, A, Cassandra, M, Madeira, M, Botelho, A, Santos, M, Nascimento, J, Goncalves, L, Naratrekoon, B, Yingchoncharoen, T, Vathesatogkit, P, Yamwong, S, Sritara, P, Soto-Ruiz, RM, Bonaque Gonzalez, J C, Abellan-Huerta, J, Rubio-Paton, R, Soria, F, Ramos, JL, Egea, S, Garcia-Gomez, J, Martinez Diaz, JJ, Castillo, JA, Penicka, M, Vecera, J, Mirica, C, Kotrc, M, Kockova, R, Zilberszac, R, Gabriel, H, Maurer, G, Rosenhek, R, De Chiara, B, Botta, L, Musca, F, Belli, O, Costetti, A, Trolese, I, Spano, F, Russo, C, Giannattasio, C, Moreo, A, Rifai, R, Berthelot, E, Le, MT, Hilpert, L, Montani, D, Sitbon, O, Jais, X, Humbert, M, Assayag, P, Gunduz, S, Yesin, M, Kalcik, M, Gursoy, MO, Cersit, S, Astarcioglu, MA, Karakoyun, S, Aykan, AC, Ozkan, M, Cersit, S, Gunduz, S, Tabakci, M, Kalcik, M, Yesin, M, Bayam, E, Ozkan, M, Devecchi, C, Degiovanni, A, Di Ruocco, MV, Marino, P, Ancona, F, Rosa, I, Stella, S, Barletta, M, Marini, C, Latib, A, Montorfano, M, Colombo, A, Margonato, A, Agricola, E, Smith, D, Ray, R, Gallagher, M, Nazir, M, Perreso, V, Sharma, R, Gargani, L, Pang, PS, Miglioranza, M, Landi, P, Dini, FL, Picano, E, Asmarats Serra, L, Pons Llinares, J, Macaya Ten, F, Pericas Ramis, P, Caldes Llull, O, Grau Sepulveda, A, Frontera, G, Bethencourt, A, 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Abstract

Background: The attainment of the primary (low density lipoprotein cholesterol; LDL-C) and the secondary (non-high density lipoprotein cholesterol; non-HDL) lipid therapeutic targets may depend on several potential factors. Our aim was assess the associations between ultrasound fat indexes, lipid levels and the lipid goals attainment in high and very high cardiovascular (CV) risk patients. Methods: Four hundred twenty (n=420) patients (F/M=146/274; age=61 ± 7 y.o.) with high (43%) or very high (57%) cardiovascular risk and chronic statin treatment (³12 months) were enrolled into the study. Obesity measures (body-mass index, BMI; bioelectrical impedance body fat; BF, waist circumference, WC, body adiposity index; BAI), serum levels of lipids (total cholesterol–TC, LDL-C, HDL-C and triglycerides–TG) and goal lipid levels (LDL-C and non-HDL-C) according to the CV risk were determined in all patients. The following ultrasound fat parameters were used in the study: intraabdominal fat (IAT), preperitoneal fat thickness (PreFT), epicardial (EFT) and pericardial (PFT) fat thickness and were indexed to BMI. Results: Our study patients had 5.2 ± 1.7 CV risk factors (80% hypertension, 32% diabetes, 59% metabolic syndrome), 49% were obese, 63% had high BF% and 85% had increased waist circumference (F>80 or M>94cm). All the patients were on a long-term statin treatment (rosuvastatin, atorvastatin or simvastatin). The attainment of the target lipid levels in the study group was as follows: LDL-C–34%, non-HDL-C–39%, both LDL-C and non-HDL-C 31%. Mean fat parameters in the study group were as follows: IAT–76.4 ± 26mm, PreFT–23.3 ± 6.5mm, EFT–3.5 ± 1.5mm and PFT–8.6 ± 3.8mm. Patients with LDL-C goal attainment had significantly higher BAI (34.6 ± 33 vs 30.5 ± 7, p=0.04), but significantly lower IAT/BMI (2.35 ± 0.7 vs 2.51 ± 0.7, p<0.05) with no differences in other clinical (BMI, BF%, WC) and ultrasound (PreFT/BMI, EFT/BMI, PFT/BMI) indexes. The LDL-C goal achievement revealed inverse association with IAT/BMI (r=-0.15, p<0.05) and no associations with PreFT/BMI, EFT/BMI or PFT/BMI. Multivariable regression analysis revealed independent association between IAT/BMI and the LDL-C goal achievement. Conclusions: Intraabdominal fat thickness representing visceral adipose tissue is inversely associated with the LDL-C goal attainment independently from general obesity. It may help to identify individuals requiring more aggressive management of dylipidaemia.

Published
2015
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50. Moderated Posters session: complementary role of imaging techniques

Author

Pontone, G, Andreini, D, Annoni, A, Petulla, M, Russo, E, Innocenti, E, Guglielmo, M, Mushtaq, S, Tondo, C, Pepi, M, Demir, OM, Bashir, A, Marshall, K, Douglas, M, Wasan, B, Plein, S, Alfakih, K, Celeng, C, Kolossvary, M, Kovacs, A, Szilveszter, B, Molnar, A, Horvath, T, Jermendy, AL, Tarnoki, AD, Merkely, B, Maurovich-Horvat, P, Llao-Ferrando, JI, Castro, JC, Vilades-Medel, D, Mirabet, S, Pons-Llado, G, Roig, E, Leta, R, Kitsiou, A N, Papanikolaou, S, Griroriou, K, Antonopoulos, M, Mpouki, M, Moustakas, G, Giougi, A, Giannakopoulos, V, Gionakis, G, Balomenos, A, Portugal, G, Abreu, A, Rio, P, Santos, V, Martins Oliveira, M, Silva Cunha, P, Mota Carmo, M, Branco, L M, Morais, L, Cruz Ferreira, R, Becoulet, L, Guijarro, D, Pallardy, A, Mathieu, C, Valette, F, Gueffet, JP, Serfaty, JM, Kraeber-Bodere, F, Trochu, JN, Piriou, N, Demir, OM, Bashir, A, Marshall, K, Wasan, B, Plein, S, Alfakih, K, Marcos-Alberca Moreno, P, Perez-Isla, L, Palacios, J, Gomez De Diego, JJ, Islas, F, De Agustin, JA, Luaces, M, Arrazola, J, Garcia-Fernandez, MA, Macaya, C, Iriart, X, Selmi, W, Jalal, Z, and Thambo, JB

Abstract

Background: The outcome of radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) has improved thanks to left atrium (LA) anatomy reconstruction by computed tomography with adaptive statistical iterative reconstruction algorithm (CT-ASIR) before the procedure. However, CT-ASIR strategy is associated to an increase of cumulative effective radiation dose (ED) in these patients. Recently, a model-based iterative reconstruction algorithm (MBIR, GE Healthcare, Waukesha,Wisconsin) has been developed (CT-MBIR) for image noise reduction reducing the ED close to chest X-ray exposure. The aim of this study is to compare the CT and RFCA characteristics, AF recurrence after procedure and radiation exposure between RFCA guided by image integration with CT-ASIR versus CT-MBIR Methods and Materials: One-hundred twenty consecutive patients with drug-refractory paroxysmal or persistent AF were addressed to CT-ASIR (Group 1; N: 60; mean age 60.3 ± 10.1 yo; male: 46) or CT-MBIR protocol (Group 2; N: 60; mean age 59.7 ± 11.3 yo; male:45) for evaluation of LA before RFCA. All patients were subsequently treated by image integration-supported RFCA. Image noise, signal to noise ratio (SNR), contrast to noise ratio (CNR), RFCA procedural characteristics, rate of AF recurrence and CT radiation exposure were measured and compared between the two groups. Results: The two groups were homogeneous in terms of demographic characteristics, cardiovascular risk factors, prevalence of persistent AF, medical therapy and echocardiographic characteristics. The mean follow-up was similar (578 ± 284 vs. 591 ± 278 days, respectively, p:ns). Group 2 showed a higher signal to noise ratio (25.9 ± 7.1 vs. 13.8 ± 5.1) and contrast to noise ratio (22.7 ± 6.5 vs. and 14.08 ± 4.1) of left atrium as compared to Group 1 (p<0.001). No differences were found in terms of RFCA parameter [procedural duration (130.9 ± 130.6. vs. 143.8 ± 80.4 min); fluoroscopy time (27.9 ± 14.1.0 vs. 32.0 ± 16.4 min); pulmonary veins isolated (3.8 ± 0.4 vs. 3.9 ± 0.4)] and the rate of AF recurrence (31% vs. 29%) between Group 2 vs Group 1. Group 2 showed a 94% reduction of ED as compared to Group 1 (0.4 ± 0.04 mSv vs 6.4 ± 1.8 mSv, p<0.01). Conclusions: CT-MBIR allows accurate non-invasive reconstruction of LA anatomy in AF patients undergoing to RFCA with a submillisievert effective radiation and comparable success rate of RFCA with CT-ASIR technique.

Published
2015
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