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Abstract Conductive flexible films are successfully synthesized from polyvinyl alcohol matrix and poly(aniline‐co‐carbazole) charge carrier. To improve the mechanical properties of polyvinyl alcohol and promote charge transition in the conductive copolymer, dual purpose sulfonated multiwall carbon nanotube is added. Conductivity is enhanced via sulfonic acid protonic dopant and mechanical property is increased by its hexagonal nanorods. Nanocomposites are prepared by adding 0.025, 0.050, and 0.075 g of carbon nanotube which is added at 1%, 3%, and 5% loads to the polymer matrix. Films are characterized by infrared, UV–vis, X‐ray diffraction, scanning electron microscopy, and thermogravimetric analysis. Conductivity is measured by the four‐probe technique and mechanical property is assessed through tensile tests and dynamic mechanic thermal analysis. A 5 × 10−6 S cm−1 conductivity and 116 MPa tensile strength are recorded for the conductive film with optimum dopant/nanocomposite loads. The electrochemical property and corrosion resistance are studied by cyclic voltammetry and Tafel curves, respectively. The conductive films show an increase in corrosion potential and a decrease in corrosion current referring to a reliable corrosion protection film. The water uptake and contact angle of the films are measured to be 157% and 80.1° respectively to confirm its required hydrophilic property.

Benzylic bromides were conveniently obtained in high yields via the reaction of the corresponding alcohols with crosslinked polyvinylpyrrolidone-bromine complex (PVPP-Br2)/hexamethyldisilane in chloroform at reflux condition. Selective conversion of benzyl alcohol to benzyl bromide in the presence of primary aliphatic alcohols, e.g. 2-phenylethanol was also achieved.DOI: http://dx.doi.org/10.4314/bcse.v26i2.14

Abstract Introduction Psoriasis is a common, chronic, and non-contagious skin disease that has no known cause or treatment. Various medical costs for skin disorders, including psoriasis, can be expensive and lifelong. The purpose of the present study was to determine the economic burden of psoriasis in patients admitted to general hospitals affiliated with Shiraz University of Medical Sciences, Iran in 2022. Materials and methods This research was a descriptive, cross-sectional, cost of illness study from a societal perspective. All psoriasis patients (N = 118) admitted to the hospitals affiliated with Shiraz University of Medical Sciences in 2022 were examined. 7 participants refused to cooperate and were excluded from the study and, the information of 111 patients was collected. A researcher-made data collection form was used to collect data. A prevalence-based approach was used to prepare cost data, and the costing approach was bottom-up. The productivity lost due to the absenteeism of patients and their companions was estimated using the human capital approach. Microsoft Excel ® 2016 was applied to analyze the data. Results The mean annual cost per psoriasis patient was estimated to be US$ 30,374.21. Its highest and lowest share was related to direct medical costs (88.61%), direct non-medical costs (7.3%) and indirect costs (4.09%), respectively. Also, the highest mean direct medical, direct non-medical, and indirect costs per patient were related to those of medicine (93.11%), transportation (51.65%), and absenteeism of the patients’ companions due to patient care (71.73%). Conclusion Considering that the major contributor in the direct medical cost of treating psoriasis patients was related to medicine, designing appropriate mechanisms for insurance coverage, and allocating government subsidies for the purchase of medicine, are suggested. The result of the current study has important implications for policymakers in developing guidelines for early diagnosis of this disease and reducing the health economic burden.

Objective: Bisphenols are a type of phenolic chemical frequently used in producing various consumer products.Owing to their widespread exposure, these compounds can cause multiple toxic effects in humans. This study aimedto assess the protective effects of zinc oxide nanoparticles (ZnONPs) against bisphenol S (BPS)-induced cytotoxicityin the human testicular embryonic carcinoma cell line (NT2/D1).Materials and Methods: In this experimental study, cytotoxic concentrations of ZnONPs and BPS on NT2/D1 cellswere optimized using the MTT assay. Thereafter, the effects of ZnONPs (50 and 500 μM), BPS (300 and 600 μM), andpre-treatment with ZnONPs (50 μM) followed by exposure to BPS (600 μM) on the expression of SOX2 and OCT4genes and apoptosis-related proteins (i.e. Bax and Bcl-2) were evaluated, using quantitative reverse transcriptasepolymerase chain reaction (qRT-PCR) and western blotting, respectively.Results: Both BPS and ZnONPs reduced the viability of NT2/D1 cells in a time- and dose-dependent manner. Pretreatmentwith 50 μM of ZnONPs increased mRNA levels of SOX2 and OCT4 and improved the reduction of cell viabilitycaused by exposure to half-maximal inhibitory concentration (IC50) of BPS (P

Objective(s): Despite the many benefits of mesenchymal stem cell (MSC) transplantation for tissue regeneration, there are some limitations to using them, including the high costs, applying invasive procedures, the possibility of transplant rejection, and cell malignancy. This study aimed to investigate the effect of secretions of bone marrow stromal cells (BMSCs) with the cell-free strategy on damaged sciatic nerve with an emphasis on the role of apoptosis and the expression of myelin protein zero (MPZ) and nerve growth factor (NGF) proteins.Materials and Methods: BMSCs were cultured and a 25-fold concentrated conditioned medium (CM) from the cells was provided. After creating a crush injury in the left sciatic nerve of male rats, BMSCs or CM were injected into the injured site of the nerve. Four weeks later, the expression of MPZ, NGF, Bax, and Bcl-2 proteins in the sciatic nerve and histological parameters of the sciatic nerve and gastrocnemius muscle were assessed.Results: The results demonstrated that injection of CM decreased apoptosis and increased expression of MPZ and NGF proteins, improving remyelination and regeneration of the sciatic nerve almost as much as the transplantation of the BMSCs themselves compared to the control group.Conclusion: The results suggest that BMSC secretions may improve remyelination and regeneration of damaged sciatic nerve by increasing the expression of MPZ and NGF and decreasing apoptosis.

Background and purpose: Unpredictable stressors cause changes in behavioral parameters such as motor and exploratory behaviors, feeding, and sexual and anxiety behaviors. Stress leads to the release of corticosteroids and, as a result, causes dysfunction in different parts of the nervous system. A decrease in the synaptic levels of serotonin or norepinephrine in different parts of the brain such as the prefrontal cortex and a decrease in BDNF production in the hippocampus may also contribute to stress-related complications. Posttraumatic stress disorder occurs in some people after facing a severe stressful event. In PTSD, the activity and function of many physiological systems are disturbed. Fluoxetine, or Prozac, is used to treat neurological disorders such as depression and anxiety and inhibits the reuptake of serotonin by the serotonin transporter (SERT) in neurons. Some studies have shown that females respond better to SSRI antidepressants than males, which may be due to the interaction between estrogenic and serotonergic pathways. BDNF is a member of the neurotrophin family and is expressed in several tissues and cells such as the brain and blood. Its role in several mental disorders, such as depression, anxiety, eating disorders, and PTSD, has been identified. SPS (single prolonged stress) as an animal model of PTSD decreases the mRNA expression of BDNF in hippocampus rats and causes anxiety-like behaviors. The role of gender differences in the effect of antidepressants and clinical interventions in psychotic diseases is also discussed. Sex hormones in women affect the pharmacokinetics and efficacy of antidepressants. Women respond better to fluoxetine than men during reproductive years. Considering the different results regarding the effectiveness of effective drugs in the treatment of psychotic diseases in both sexes, in this study, we aim to investigate the response of male and female rats exposed to stress to the trial of fluoxetine. Materials and methods: In this experimental study, Wistar male and female rats with an average weight of 200-250 grams were used (56 animals, 8 groups of 7). The selection of the number of animals was based on previous studies in this field. After the drug intervention period, and fear and anxiety suppression test, the animals were killed under deep anesthesia, and a blood sample was collected to prepare serum to measure BDNF and corticosterone levels (using the Eliza kit of Germany Zelbio Company and according to the kit protocol). All experiments were performed according to the laboratory animal protocol of Mazandaran University of Medical Sciences. The work steps are as follows: 1. Creation of PTSD through SPS was done in three stages, 2. Drug intervention: the drug dose for all groups is 10 mg/kg/day for 4 weeks dissolved in drinking water, 3. Evaluation of anxiety-like behaviors with the light-dark box (L/D BOX), 4. Evaluation of the ability to forget painful memories with the fear silence test, 5. Measurement of BDNF and corticosterone in serum by Eliza method. Results: In this study, it was observed that male and female rats that were exposed to single prolonged stress showed a decrease in fear extinction an increase in anxiety-like behaviors in the dark-light box test, and an increase in serum corticosterone. Fluoxetine led to an increase in the percentage of fear extinction, a decrease in the Entrance Latency in the light area, the Time in the Light Compartment, the number of rearing, and a decrease in serum corticosterone significantly in both sexes(P

In this study, The surface plasmon excitations in a dimer structure of closely spaced metallic nanospheres with different radii are investigated using the hydrodynamic model. Initially, an expression was derived to calculate this structure's multipolar surface plasmon excitations. Subsequently, the surface plasmon excitations in the dipole approximation were examined.The surface plasmon excitations in a dimer structure of closely spaced metallic nanospheres with different radii are examined using the hydrodynamic model in this study. It has been observed that the energy of in-phase modes is lower than that of out-of-phase modes in longitudinal or transverse excitations. Furthermore, at each separation distance between the nanospheres, the energy difference between in-phase and out-of-phase longitudinal modes is greater than that of transverse modes. The results show that with an increase in the separation distance between the nanospheres, the energies of in-phase modes increase, and the energies of out-of-phase modes decrease. At large separation distances, two plasmon modes are obtained, with the higher energy mode corresponding to the smaller nanosphere and the lower energy mode corresponding to the larger nanosphere. Finally, the local limit results are presented for comparison.

The purpose of this study was to investigate the effects of novel edible films produced by incorporating Dracocephalum kotschyi (D. kotschyi) essential oil nanoemulsion into a polymeric matrix (chitosan-gelatin) with grape preservative potential during room temperature storage. To achieve this goal, the edible films' mechanical, microstructural, and physical characteristics were examined. Next, an antimicrobial analysis was conducted on five food-borne pathogens, and the results indicated that edible films with 5 % essential oil (ChG4) might be efficiently produced to have antibacterial action against particular pathogens. Additionally, the integration of the nanoemulsion resulted in the creation of microporous structures in edible films, as demonstrated by SEM studies. A positive impact of ChG4 edible film on grape preservation during 15 days’ storage was observed. The findings afford an innovative approach for the expansion of effective herbal antimicrobial formulation for food preservation.

Background and purpose: Post-traumatic stress disorder (PTSD), a type of psychiatric disorder that occurs after exposure to traumatic events, is associated with anxiety and abnormality in the activity of hypothalamic-pituitary-adrenal axis and cognitive functions. Physical activity can improve symptoms of somatic and neuropsychiatric disorders; however, appropriate exercise intensity and duration are still in question. In the present study, the effects of high-intensity exercise on anxiety-like behaviors, fear extinction, serum insulin-like growth factor (IGF-1), brain-derived neurotrophic factor (BDNF), and expression of apoptosis-related genes were investigated in the prefrontal cortex of the rat PTSD model. Materials and methods: In this experimental study, single prolonged stress (SPS) was used to induce PTSD in adult male Wistar rats. After 10 days, the animals in the exercise groups were subjected to high-intensity treadmill exercise (20 m/min, 5 days/week) for four weeks. Next, anxiety-like behaviors and fear extinction were examined using open field and shuttle box tests, respectively. Thereafter, serum IGF-1 and brain BDNF were measured by ELISA kits; and expression of Bax, Bcl-2, and caspase-3 in the prefrontal cortex were measured by real-time PCR. Results: SPS rats showed increased anxiety and decreased fear extinction, serum IGF-1, and prefrontal BDNF compared to the control animals. In addition, SPS induced apoptosis by an increase in Bax and caspase-3 and a decrease in Bcl-2. High-intensity exercise reduced apoptosis and increased serum IGF-1 significantly (P

Background and purpose: Post-traumatic stress disorder (PTSD) is a psychotic disorder that occurs in people who have faced with various types of stressors. However, the efficacy of drug and psychotherapy methods, even in combination is still low. Therefore, complementary treatments are being researched. The relative improvement of PTSD has been observed with the use of Serotonin Selective Reuptake Inhibitors (SSRIs). The effect of exercise has also been determined in improving physical and mental health. But the appropriate exercise intensity is still in question. Therefore, the aim of this study was to investigate the effect of intense exercise, fluoxetine, and their combined treatment on behavioral, molecular, and cellular damages caused by a standard model of PTSD. Materials and methods: Single prolonged stress (SPS) was used as a model to induce PTSD. Exercise (1 hour, 15 m/min) was planned for five days per week and fluoxetine (10 mg/kg/day) dissolved in drinking water was administered for four weeks. After performing the anxiety test, the animals were killed under deep anesthesia and blood samples were collected to measure IGF-1 serum levels by ELISA method and prefrontal cortex was frozen to measure apoptotic factors by RT-PCR method. Results: SPS rats showed increased anxiety levels and decreased serum IGF-1 levels. Increased Bax and Caspase-3 mRNA expression, and decreased Bcl2 mRNA expression were found in the prefrontal cortex. Exercise, fluoxetine, and their combined intervention increased IGF-1, decreased the expression of pro-apoptotic factors, and increased the expression of anti-apoptotic factors. The results showed that the combined intervention of exercise and fluoxetine could reduce the anxiety caused by SPS. Conclusion: Considering that fluoxetine was more effective in comparison with high-intensity exercise, it is clear that in the groups that were affected by both interventions; fluoxetine played a more significant role.

In order to investigate the impact of a technology on the business model, it is necessary to examine the characteristics of that technology and how to use those characteristics in order to benefit from opportunities and deal with threats, so the purpose of this research is to investigate the characteristics of blockchain on financial innovations. The statistical population of this research is more than 100 thousand people and the statistical sample using Morgan's table is 384 people. Information is collected by library, field and internet methods. The validity of this questionnaire was confirmed by experts and supervisors. Also, the measuring tool is a questionnaire. The questionnaire was designed by Latman (2016) and has 36 questions. Data analysis software is the Spss software package. A 5-point Likert scale was used for the questionnaire. The research results showed that some of the key features of blockchain technology will have a direct impact on the banking industry. These key features include dynamism, identity preservation, information security, lower cost, time saving, trust building, decentralized and impenetrable blockchain technology and financial innovations and value transfer in banking. Each of these features will affect different aspects of the business model.

Abstract In this study, a new and efficient Rod-like bifunctional Fe-based MOF@CuO nanocomposites (RL BF Fe-based MOF@CuO NC) were synthesized as new and efficient heterogeneous catalyst through a simple method from easily available 1,3,5-benzenetricarbocylic acid linker, nitrate ferric as a source of iron and copper oxide (CuO) nanoparticles under microwave irradiation. The synthesized nanocatalysts were characterized with different techniques such as Brunauer–Emmett–Teller (BET), energy dispersive spectroscopy (EDS), field emission scanning electron microscopy (FE-SEM), mapping, transmission electron microscopy (TEM), X-ray diffraction (XRD), vibrating sample magnetometer (VSM), thermogravimetric analysis (TGA) and Fourier transform infrared spectroscopy (FT-IR). The RL BF Fe-based MOF@CuO NC had relatively high specific surface area (203 m2 g−1) while exhibiting superparamagnetic properties. The catalytic activity of RL BF Fe-based MOF@CuO NC was explored in a facile and green methodology to prepare diverse N‑amino-2-pyridones by one-pot four component reactions comprising aromatic aldehyde, malononitrile, methyl cyanoacetate and hydrazine hydrate within mild and solvent-free conditions. This protocol enjoys features like providing the final products during low reaction times in excellent yields under solvent-free conditions. The use of easily available and inexpensive reactants for the synthesis of the catalyst, environmental compatibility, low catalyst loading, fast and clean work-up and reusability of catalyst for several cycles with consistent activity are counted as the outstanding features of this procedure.

Background and purpose: Allicin has a wide range of pharmacological functions, all of which can be demonstrated in anti-inflammatory, antioxidant, antifungal and anti-tumor activities. In this research, we investigated the neuroprotective role of allicin in the process of diffuse traumatic brain injury and its effect on interleukin levels and histological changes in rats. Materials and methods: In this experimental study, Wistar rats (n=56) underwent diffuse controlled brain injury by Marmarou method, and 30 minutes later, the drug was injected intraperitoneally at different doses. Veterinary Coma Scale was used and Beam Walk and Beam Balance movement and balance tests were taken at pre-traumatic times, immediately after recovery from the trauma, and 24, 48, and 72 hours after the trauma. Results: Findings showed that allicin at 25 mg/kg and 50 mg/kg can reduce these differences compared to the control group (Sham and Intact) (P

Background: Numerous studies have predicted investment decision-making behavior as one of the most important decisions of individuals and the effects of financial literacy on it. But research that has simultaneously mediated the role of financial self-efficacy and financial literacy in relation to cognitive abilities and investment decision-making behavior has Been neglected. Aims: The aim of this study was to determine the relationship between cognitive abilities and investment decision-making behavior of Tehran Stock Exchange investors with mediating role of financial self-efficacy and financial literacy. Methods: In the present descriptive-correlational study, the study population included all active investors in Iran's capital market. From the statistical population, 380 people were selected by available sampling method. During the sampling process, it was attempted to select investors with at least one year of activity in the capital market. The research instruments included the Cognitive Abilities Questionnaire (nejati, 2013), the Financial Self-Efficacy Questionnaire (lown, 2011), the Financial Literacy Questionnaire (Bongomin et al, 2016), and the Decision Decision Behavior Questionnaire (lim, 2012). The collected data were analyzed by structural equation modeling. Results: The results showed that cognitive abilities have a positive and significant relationship with investment decision-making behavior (p

Objective: Peripheral nerve injury is a clinical problem that may cause sensory and motor inabilities. Sesamol is an antioxidant that can help in repairing damaged central nervous system (CNS) and other organs. The present study aimed to investigate whether the antioxidant effects of sesamol could improve the function, structure, and myelination in rats’ damaged peripheral nervous system (PNS).Materials and Methods: In this study, 28 adult male Wistar rats were randomly divided into four groups. In the sham group, the sciatic nerve was exposed and restored to its place without inducing crush injury. The control received DMSO (solvent) and the two experimental groups received 50 or 100 mg/kg sesamol intraperitoneally for 28 days after sciatic nerve crush injury, respectively. Next, sciatic function index (SFI), superoxide dismutase (SOD) activity, malondialdehyde (MDA) level, expression of nerve growth factor (NGF) and myelin protein zero (MPZ) proteins in the sciatic nerve, and histological indices of the sciatic nerve and gastrocnemius muscle were evaluated. Results: The results showed that sesamol reduced oxidative stress parameters, increased expression of NGF and MPZ proteins, and improved function and regeneration of the damaged sciatic nerve. Furthermore, a significant regeneration was observed in the gastrocnemius muscle after treatment with sesamol. Although administration of both doses of sesamol was useful, the 100 mg/kg dose was more effective than the 50 mg/kg one.Conclusion: The results suggest that sesamol may be effective in improving damaged peripheral nerves in rats by reducing oxidative stress and increasing the expression of NGF and MPZ proteins.

The cheap and easy technology of biological weapons has become a legitimate threat, now. This is no longer limited to the realm of a scientific mythology, nor is it limited to specific geographical areas. Biological terrorism (bioterrorism) against individuals may cause death, disease, weakness and panic in a society, cause social disruption and become a threat to international peace, security, and public order. Using a descriptive-analytical method, the present study delves into the subject matter of this phenomenon, to express the nature and characteristics of biological attack and then in light of the principles and sources in international law and Islam gives a jurisprudential and legal analysis of biological attack. According to Islamic law and jurisprudence, the tenets of human rights and especially the right to life, and moral values, any biological weapon in any form that targets the innocent and the civilians is not allowed; It is indeed more of a “bloodshed” in that many innocents are killed and is a prototype example of “corruption on Earth” as presumed in Islam.

In this study, a novel highly sensitive and selective fluorescent optode membrane aimed at the determination of Pb(II) ion is proposed by incorporating N-(3-(1,4-dioxa-7,13-dithia-10-azacyclopentadecan-10-yl)propyl)-5-(dimethylamino)naphthalene-1-sulfonamide (L) as fluoroionophore in polyvinyl chloride (PVC) containing 2-nitrophenyl octylether (NPOE) as a plasticizer. In addition to high stability and reproducibility, the proposed optosensor showed a unique selectivity toward Pb(II) ion, with a wide linear range of molar concentrations (1.0 × 10−9–1.0 × 10−3 M) and a low detection limit of 7.5 × 10−10 M in solution at pH 5.0. The formation constants of the Pb(II) complexes with the fluoroionophore were evaluated by fitting the fluorescence data with a nonlinear least-squares curve-fitting program, and further information about the structures of the complexes were evaluated based on hybrid-DFT calculations. The optosensor exhibited a fast response time of less than three min, being easily regenerated by exposure to a solution of dithiothreitol. The sensor was applied to the determination of Pb(II) in real samples (canned tuna fish), and it provided satisfactory results comparable to those obtained via atomic absorption spectrometry (AAS).

Background and purpose: Exposure to organophosphorus (OP) compounds may contribute to an increased risk of cognitive impairments and induction of oxidative stress. The present study was designed to evaluate the effects of exposure to paraoxon (the active metabolite of insecticide parathion) on cognitive function and oxidative stress biomarkers. Materials and methods: Adult male Wistar rats (n= 56, 7 per group) were used in this study. Corn oil or paraoxon at 0.3, 0.7, or 1 mg/kg were intraperitoneally administrated. After 14 or 28 days, the animals were examined by Morris water maze to determine spatial learning and memory. The effects of paraoxon on hippocampal glutathione (GSH) and malondialdehyde (MDA) levels were also investigated. Results: Escape latency and swimming distance significantly increased in animals that received 1 mg/kg of paraoxon at both time points (P0.05). Exposure to paraoxon 1 mg/kg was associated with decreased GSH and increased MDA levels in the hippocampus. Conclusion: The study showed that exposure to high dose of paraoxon (1 mg/kg) impaired spatial learning and memory independent of any changes in sensorimotor deficit. Induction of oxidative stress plays an important role in development of cognitive impairments caused by exposure to paraoxon.

Introduction: Despite many challenges, public-private partnership in hospitals is recognized as one of the most attractive investment platforms for the private sector. This study conducted to assess the challenges of private sector partnership with public hospitals using the public-private partnership model in public hospitals in Yazd. Methods: The present qualitative research conducted in 2021. The viewpoints of 15 faculty members, directors, managers and operational experts on the participation of the private sector, those related to the transfer and contracts and the parties of the private sector are extracted through a semi-structured interview guide and analyzed using content analysis in three stages. Results: A total of 10 main themes including economic and policymaking problems, insufficient manpower readiness, lack of support authority, weak partnership laws, lack of knowledge and experience of managers in partnership, lack of financial transparency, conflict of interest, poor coordination, lack of cultural readiness and trust-building and lack of plans and supervision in the field of partnership in 28 sub-themes extracted. Conclusion: There are challenges related to policymaking issues and the resulting instability, incoordination of different units, unpreparedness of manpower and contract details in using different models of public-private partnership in hospitals, in which the use of the same procedures, transparency and the meeting requirements of the private sector are recommended for partnership and the formulation of laws and contracts free from any shortcomings and weaknesses that could lead to the loss of the public sector.

One of the mystical metaphors in the poems of mystical poets is the comparisonof the word and meaning of idol with Almighty God. Several aspects can be foundIn this metaphor: First, an aesthetic look at the idol; an idol is an adorable beautythat possesses everything that deserves its perfection. The second is the glorifyingapproach to the idol. In this sense, the idol is the coquettish beloved, who is gentleand careless and indifferent to his own lovers. The Idol is also a stoneheartedbeloved, who, of course, apparently ignores the enthusiasts for their own interests.The description of Almighty God with the word idol is in clear contradiction withthe belief system of Islam. What do mystics such as Hafiz and Imam Khomeinimean by idol and attributes and manifestations attributed to him regarding God?The hypothesis of this research is that, regardless of the negative meaning of theidol, which is rarely reflected in the works of these two figures, in their mysticalview, the idol regarding the Almighty God is the truth and regarding the idol thatthe pagans adorn and worship is figurative.

Background and purpose: Post-traumatic stress disorder (PTSD (is a psychotic illness caused by different types of stressors and is associated with high economic and psychological burdens on health systems. Physiological studies of the brain have shown that serum corticosterone and insulin-like growth factor 1 (IGF-1) levels have important roles during brain damage and trauma to the nervous system. In this project, we studied the effect of exercise as an effective factor on improving anxiety and serum levels of corticosterone and IGF-1in male PTSD rats. Materials and methods: In this experimental study, single prolonged stress (SPS) was used to induce PTSD in male Wistar rats. The animals were divided into two groups: Sham (Non-SPS [NSPS]) and SPS. The two groups were then divided into two subgroups and one of the subgroups in each group did the exercise after two weeks which continued for four weeks according to the following program: moderate treadmill exercise, 5 days a week; the first two weeks 10m/min and the second two weeks 15m/min). Then, anxiety test was performed by open field test and serum levels of IGF-1 and corticosterone were measured using Eliza. Results: The rats in SPS group exhibited increased anxiety levels in open field test, decreased serum IGF-1 levels, and increased serum corticosterone levels compared with the controls. Moderate treadmill exercise alleviated SPS-induced alterations, anxiety, and IGF-1 and corticosterone levels. Conclusion: Moderate exercise could be used as a useful complementary treatment in behavioral and molecular injuries in PTSD patients.

Background: Dynamic protein-protein interaction networks (DPPIN) can confirm the conditional and temporal features of proteins and protein complexes. In addition, the relation of protein complexes in dynamic networks can provide useful information in understanding the dynamic functionality of PPI networks. Objective: In this paper, an algorithm is presented to discover the temporal association rule from the dynamic PPIN dataset.Material and Methods: In this analytical study, the static protein-protein interaction network is transformed into a dynamic network using the gene expression thresholding to extract the protein complex relations. The number of presented proteins of the dynamic network is large at each time point. This number will increase for extraction of multidimensional rules at different times. By mapping the gold standard protein complexes as reference protein complexes, the number of items decreases from active proteins to protein complexes at each transaction. Extracted sub graphs as protein complexes, at each time point, are weighted according to the reference protein complexes similarity degrees. Mega-transactions and extended items are created based on occurrence bitmap matrix of the reference complexes. Rules will be extracted based on Mega-transactions of protein complexes. Results: The proposed method has been evaluated using gold standard protein complex rules. The amount of extracted rules from Biogrid datasets and protein complexes are 281, with support 0.2. Conclusion: The characteristic of the proposed algorithm is the simultaneous extraction of intra-transaction and inter-transaction rules. The results evaluation using EBI data shows the efficiency of the proposed algorithm.

Noise is one of the most harmful factors in the work environment, which is very important to control. There are various techniques to achieve this goal. One of the most important of them is the use of noise absorbers. Absorbent materials are often used to counteract the effects of reflected noise from hard surfaces and reduce their level. This is an experimental-applied study conducted in the physical factor laboratory of the Faculty of Health. The purpose was to predict the Noise absorption rate of combined and independent absorbers under different conditions and frequencies using the new ENC (engineering noise control) software. The sound absorption determination was carried out in 5 stages, including sound frequency analysis for the source, measurement of the dominant frequency, measurement of the absorption coefficient of absorbent materials in different conditions, measurement of the limit frequency (peak frequency of noise absorption) and comparison of the software results with the findings of the impedance tube in Real conditions. The best absorption mode for combined and independent absorbents is using a 5 cm rock wool absorbent with a 2 cm thick air layer behind it without a polyurethane absorbent layer and a 10 cm wide rock wool absorbent with a 1 cm air layer behind it without polyurethane layer. A polyurethane layer on the stone wool absorber decreased the amount of noise absorption for high frequencies. The results obtained from the best absorption conditions in the ENC software were consistent with the findings from the impedance tube device in real situations. The results of this study showed that suitable and optimal conditions of sound absorption could be achieved by using the ENC software, correct design, use of suitable absorbers, changes in the physical parameters of the absorber, and the use of a combined absorber.

A factorial experiment (3 × 7) was conducted according to randomized complete block design (RCBD) with three replications in the open field of the research station B belong to College of Agric. Eng. Sci., University of Baghdad, ALJadriya for the period from 15/12/2016 to 1/12/2017 to study the effect of spraying boron and Sorbitol and Mannitol on the growth, quantity and quality of the yield and quantity of seeds produced from the pepper plant cv. California wonder. The experiment included two factors, first one was Boron (0, 50, 100 mg l-1) and the second factor was Sorbitol (15, 25, 35 g, l-1) and Mannitol (10, 20 and 30 g, l-1) in addition to the control treatment (spraying with water), The results showed that boron at concentration 100 mg l-1 significantly increased the fresh and dry weight of the vegetative growth (2242.4,428.4 g plant-1 respectively), dry weight of the roots (64.9 g plant-1), vitamin C (91.238 mg 100gm-1 ), carbohydrate (5.54 mg g-1), proteins (5.09 mg l-1), plant production (4.423 kg plant-1), weight of seed produced (7.35 g kg-1 fruits) and specific weight of seeds (6.717 g). Significant superiority of Mannitol at concentration 30 mg l-1 in the fresh and dry weight of vegetative growth, dry weight of roots, vitamin C, carbohydrates, plant production, weight of seed produced and specific weight (2541.0 g plant-1, 461.0 g plant-1, 72.519 g plant-1, 92.667 mg 100 g-1, 5.797 mg g-1, 4.823 kg plant-1, 8.501 g kg -1 fruits and 7.206 g, respectively). The interaction between two variables was significant for all the studied traits, this showed that the response of pepper to first variable related to the other variable. It could be concluded that the best combination between two variables was boron (100 mg l-1) and sugar alcohols (mannitol 30 g l-1). [ABSTRACT FROM AUTHOR]

We report a case of Subcutaneous Fat Necrosis (SCFN) of a newborn which is an uncommon disorder, occurs during the first year of life, and has been attributed to perinatal stress. SCFN usually has a favorable prognosis, with complete autoresolution of subcutaneous lesions within several weeks or months, but it may also be complicated by serious metabolic alterations such as hypercalcemia. [ABSTRACT FROM AUTHOR]

Abstract This paper investigates two parameters effect on vibrational responses of the spiral bevel gear. Changing the gear system overall stiffness (GSOS) considering elastic deformation and periodic torques are the two parameters which are represented as the main goals of this study. In order to investigate the effects of shaft stiffness and elastic deformation, two different cases with different support locations are considered. The first case is presented by locating the support close to the gear, and in the latter one, the distance between gear and support is increased. Besides, to study the effect of torque, two main types are considered: constant and periodic excitation torque. To illustrate the dynamic behavior, the governing differential equations are solved numerically according to the Runge–Kutta method. The equations are nonlinear due to backlash and time-varying coefficients as the results of GSOS variation. Vibrational phenomena are illustrated by means of bifurcation diagrams, RMS, and Poincaré maps. Particular vibrational behaviors such as “chaos” and “period-doubling” phenomena are illustrated with details. By investigating the effect of shaft stiffness, results show that when the support is far away from gear, the vibration response increased by 67.5%. Moreover, while the input torque is constant, the support movement does not cause undesirable responses such as chaotic or period-doubling responses. The periodic torque causes undesirable responses such as chaos and bifurcation and period-doubling responses. Article Highlights What is done in the present paper can be mentioned in three main parts: The nonlinear dynamics of the spiral bevel gear pair under two different support situations is investigated in this paper. To scrutinize the dynamic behavior of the spiral bevel gear-pair in a nearly real situation, the input driver torque is periodically variable. The results show that the spiral bevel gear pair may comprise chaotic response with periodic torque excitation if the bearing supports locate far enough from the gears.

In gear transmissions, vibration causes noise and malfunction. In actual applications, misalignments contribute to intensifying the destructive effect of vibrations. In this paper, the nonlinear dynamics of a spiral bevel gear pair, with small helix angle, considering different misalignments, are deeply investigated. Axial misalignment, radial misalignment, and the combination of these two types are considered in this study. The governing equation is numerically solved through an implicit Runge–Kutta scheme. Since the main goal of this study is the analysis of the dynamic scenario, the mesh stiffness of the gear pair is obtained from the literature. The dynamical system is nonlinear and time-varying; it is analyzed through time responses, phase portraits, Poincaré maps, and bifurcation diagrams. Results show that, among the considered three cases with different types of misalignments, the spiral bevel gear with axial misalignment is the worst destructive case; aperiodic, subharmonic, and multiperiod responses are observable for this case. It is interesting that the chaotic responses for the case, having both types of misalignments, are less likely for the case with axial misalignment, only.

Some similarities in the elements and components of the story of Adam (AS) are about Adam's rebellion, the relationship between Adam's descent and his caliphate, the divine covenant, and the divine names. The questions that arise in the mind of the audience and interpretations reveal the need for a hermeneutic analysis of this issue. Meybodi and Gonabadi have deciphered the similar, symbolic, and cryptic themes of Adam's story with a mystical approach. The reason for choosing these two interpretations is that both of them by using mystical interpretation and the cryptographic language have tried to clarify some ambiguous elements of this story. The story of Adam is full of secrets and mysteries addressed in past commentary books with different interpretations. The Quranic interpretations choose various approaches such as rational, narrative, ijtihad, mystical, etc. Among them, mystical interpretations in terms of hermeneutic approach and the use of symbolic language have been more powerful and attractive in clarifying the semantic ambiguities of the verses. Among these interpretations, the interpretation of Meybodi’s Kashf-al asrar and Gonabadi’s Bayan-al Saadat fi maghamat-al Abadat could be mentioned In the present study, we deal with the interpretable elements of the story of Adam (AS) in the above-mentioned works. In this qualitative study, the data were collected using the content analysis method. From a hermeneutic point of view, Meybodi and Gonabadi, while expressing various meanings of the divine names and words, by expressing their depth and mystery have provided the audience with a way to offer other interpretations and, based on modern hermeneutics, consider the final meanings impossible. However, they have not explicitly stated this. In the mystical interpretation of the similarities of the story of Adam (AS), Gonabadi takes an approach which focuses on ijtihad and reasoning while Meybodi uses a tasteful approach with a mystical and romantic tone. Both commentators have tried to find an interpretation of Adam's rebellion or infallibility, but in all the verses of Adam’s story, it seems that the prohibition of eating the fruit of the tree was for the sake of guidance and benevolence. Meybodi considers the divine names as subtle points or the secrets of God which have been entrusted in the heart of Man by the command of God, and no other being is worthy of carrying the divine trust. Yet, Gonabadi believes that the divine names are in Adam’s intelligence. In the Holy Qur'an, a combination of traditional and modern hermeneutic approaches can be seen. In similar verses, on the one hand, the knowledge of the intention of the author, who is God, is important; on the other hand, it is not possible to reach the final meanings because the celestial text originates from a vast and infinite source of knowledge which is not limited.

Todays, satellite broadcasting has become one of the most important areas in international arena, so that global and regional satellite communications have overshadowed many communication activities and have experienced a new course of progress and path. The role and position of satellite television networks in the transmission of news and information is expanded that, on the one hand, has created a new type of communication in the world of media, and on the other hand, has transformed the traditional equations in this regard. Meanwhile, the cessation of satellite networks or the boycott of the media has deprived the audience of access to news and information, as well as political and cultural … views. Furthermore, unilateral boycott and cessation of satellite networks’ broadcasting is not compatible with legal principles and rules. The present research, through a descriptive-analytic method and a comparative study in sources and foundations of international law and Islamic law, has analyzed and examined the practical components of live broadcast content of satellite programs.

Background: Bisphenol-S (BPS), as a new human public health concern, was introduced to the plastic industry by BPA-free labeled products following the restrictions of Bisphenol-A (BPA) as a safe alternative. However, recent research has revealed a controversial issue. In this regard, the present study aimed to review the relationship between BPS exposure and reproductive system dis/malfunction. Methods: PubMed and other databases were searched up to January 2021. The standard mean difference (SMD) with a 95% confidence interval (CI) was calculated for the main parameters using the random-effects model. Finally, 12 studies with 420 subjects were included in this research. Forest plot, meta-regression, and non-linear dose-response effect were calculated for each parameter by random-effects model. Results: Based on the results of in vitro assessment, a significant increase was found in the oxidative stress parameters, including superoxide dismutase (SMD: 0.63, 95% CI: 0.321, 0.939), thiobarbituric acid reactive substances (SMD: 0.760, 95% CI: 0.423, 1.096), and reactive oxygen species (SMD: 0.484, 95% CI: 0.132, 0.835). In addition, the hormonal assessment revealed a significant decrease in male testosterone concertation (SMD: -0.476, 95% CI: -0.881, -0.071). Moreover, in vivo examination revealed a significant decrease in hormonal parameters, such as female testosterone (SMD: -0.808, 95% CI: -1.149, -0.467), female estrogen (SMD: -2.608, 95% CI: -4.588, -0.628), female luteinizing hormone (SMD: -0.386, 95% CI: -0.682, -0.089), and female follicle-stimulating hormone (FSH) (SMD: -0.418, 95% CI: -0.716, -0.119). Besides, linear and non-linear correlations were detected in the main parameters. Conclusion: In conclusion, based on the current meta-analysis, BPS was suggested to be toxic for the reproductive system, similar to the other bisphenols. Moreover, a possible correlation was indicated between oxidative and hormonal status disruption induced by BPS in male and female reproductive systems dis/malfunction.

Abstract In this work, band gap, photoluminescence and biological properties of new bionanocomposites based on polyaniline (PANi)/hydrolyzed pectin (HPEc)/cadmium sulfide (CdS) QD nanoparticles (NPs) were studied. In order to improve the morphology and properties, CdS NPs were modified with epichlorohydrin to obtain the modified CdS (mCdS). The CdS@HPEc-g-PANi and mCdS@HPEc-g-PANi samples were synthesized via heterogeneous chemical polymerization and characterized by FTIR, 1HNMR, SEM/XRD, EDX/TEM/EDX-mapping and TGA analyses. The objective of this work is the study of physical, optical and cytotoxicity properties of the nanocomposites and comparison between them. The SEM, XRD and TGA images showed that the modification of NPs resulted in homogeneous morphology, increase of crystalline structure and high thermal stability which influenced on physical and biological property. According to UV-DRS analysis, the mCdS@HPEc-g-PANi indicated lower energy gap compared to the CdS@HPEc-g-PANi nancomposite. The presence of conductive polymer and synergy effect between the PANi and CdS caused higher PL intensity in the CdS@HPEc-g-PANi nanocomposite compared to pure CdS. The emission intensity in the mCdS@HPEc-g-PANi nanocomposite was reduced since the organic modifying agent cause reducing emission intensity. The mCdS@HPEc-g-PANi nanocomposite, due to more compatibility of organic agent with cellular walls of biological cells that help to the diffusion of metal CdS NPs into cell tissue indicated more toxicity effect on cell growth.