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133 results on '"Moses, Prabhakar"'

2. The Duration of Intestinal Immunity After an Inactivated Poliovirus Vaccine Booster Dose in Children Immunized With Oral Vaccine: A Randomized Controlled Trial

Author

John, Jacob, Giri, Sidhartha, Karthikeyan, Arun S., Lata, Dipti, Jeyapaul, Shalini, Rajan, Anand K., Kumar, Nirmal, Dhanapal, Pavithra, Venkatesan, Jayalakshmi, Mani, Mohanraj, Hanusha, Janardhanan, Raman, Uma, Moses, Prabhakar D., Abraham, Asha, Bahl, Sunil, Bandyopadhyay, Ananda S., Ahmad, Mohammad, Grassly, Nicholas C., and Kang, Gagandeep

Published
2017

7. Factors Predicting Blood Culture Positivity in Children With Enteric Fever

Author

Srinivasan, Manikandan, primary, Sindhu, Kulandaipalayam Natarajan, additional, Ramanujam, Karthikeyan, additional, Ramasamy, Ranjith Kumar, additional, Subramaniam, Sathyapriya, additional, Ganesan, Santhosh Kumar, additional, Vajja, Swathi, additional, David, Anita Shirley, additional, Lankala, Pramitha, additional, Rose, Winsley, additional, Moses, Prabhakar D, additional, Grassly, Nicholas C, additional, Kang, Gagandeep, additional, and John, Jacob, additional

Published
2021
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9. Griscelli syndrome

Author

Kumar T, Ebenazar Sam, and Moses Prabhakar

Subjects
Griscelli syndrome, hypertriglyceridemia, silvery hair, Dermatology, RL1-803
Abstract

Partial albinism with immunodeficiency is a rare and fatal immunologic disorder characterized by pigmentary dilution and variable cellular immunodeficiency. It was initially described in 1978. Primary abnormalities included silvery grayish sheen to the hair, large pigment agglomerations in hair shafts and an abundance of mature melanosomes in melanocytes, with reduced pigmentation of adjacent keratinocytes. We describe a child with Griscelli syndrome who presented with hepatitis, pancytopenia and silvery hair. The diagnosis was confirmed by microscopic skin and hair examination.

Published
2006

16. Acoustic Scene Analysis using Analog Spiking Neural Network

Author

Anand Kumar Mukhopadhyay, Moses Prabhakar Naligala, Divya Lakshmi Duggisetty, Indrajit Chakrabarti, and Mrigank Sharad

Subjects
Signal Processing (eess.SP), FOS: Computer and information sciences, Emerging Technologies (cs.ET), Computer Science::Neural and Evolutionary Computation, FOS: Electrical engineering, electronic engineering, information engineering, Computer Science - Neural and Evolutionary Computing, Computer Science - Emerging Technologies, General Medicine, Neural and Evolutionary Computing (cs.NE), Electrical Engineering and Systems Science - Signal Processing
Abstract

Sensor nodes in a wireless sensor network (WSN) for security surveillance applications should preferably be small, energy-efficient, and inexpensive with in-sensor computational abilities. An appropriate data processing scheme in the sensor node reduces the power dissipation of the transceiver through the compression of information to be communicated. This study attempted a simulation-based analysis of human footstep sound classification in natural surroundings using simple time-domain features. The spiking neural network (SNN), a computationally low-weight classifier derived from an artificial neural network (ANN), was used to classify acoustic sounds. The SNN and required feature extraction schemes are amenable to low-power subthreshold analog implementation. The results show that all analog implementations of the proposed SNN scheme achieve significant power savings over the digital implementation of the same computing scheme and other conventional digital architectures using frequency-domain feature extraction and ANN-based classification. The algorithm is tolerant of the impact of process variations, which are inevitable in analog design, owing to the approximate nature of the data processing involved in such applications. Although SNN provides low-power operation at the algorithm level itself, ANN to SNN conversion leads to an unavoidable loss of classification accuracy of ~5%. We exploited the low-power operation of the analog processing SNN module by applying redundancy and majority voting, which improved the classification accuracy, taking it close to the ANN model., Comment: 21 pages, Journal

Published
2019
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20. The psychometric properties of Beck Depression Inventory for adolescent depression in a primary-care paediatric setting in India

Author

Russell Sushila, Moses Prabhakar D, Basker Mona, and Russell Paul

Subjects
Pediatrics, RJ1-570, Psychiatry, RC435-571
Abstract

Abstract Background There is increasing interest in identifying adolescents with depression in primary care settings by paediatricians in India. This article studied the diagnostic accuracy, reliability and validity of Beck Depression Inventory (BDI) while used by paediatricians in a primary care setting in India. Methods 181 adolescents attending 3 schools were administered a back translated Tamil version of BDI by a paediatrician to evaluate its psychometric properties along with Children's Depression Rating Scale (CDRS-R) for convergent validity. Clinical diagnosis of depressive disorders, for reference standard, was based on ICD-10 interview by an independent psychiatrist who also administered the Impact of Event Scale (IES) for divergent validity. Appropriate analyses for validity and diagnostic accuracy both at the item and scale levels were conducted. Results A cut-off score of ≥ 5 (Sn = 90.9%, Sp = 17.6 %) for screening and cut-off score of ≥ 22 (Sn = 27.3%, Sp = 90%) for diagnostic utility is suggested. The 4 week test – retest reliability was good (r = 0.82). In addition to the adequate face and content validity, BDI has very good internal consistency (α = 0.96), high convergent validity with CDRS-R (r = 0.72; P = 0.001), and high discriminant validity with IES (r = 0.26; P = 0.23). There was a moderate concordance rate with the reference standard (54.5%) in identifying depression among the adolescents. Factor analysis replicated the 2-factor structure explaining 30.5 % of variance. Conclusion The BDI proved to be a psychometrically sound measure for use by paediatricians in a primary care setting in India. The possibility of screening for depressive disorders through the use of BDI may be helpful in identifying probable cases of the disorder among adolescents.

Published
2007
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22. Genotype distribution of Group A rotavirus from southern India, 2005–2016

Author

Babji, Sudhir, primary, Arumugam, Rajesh, additional, Priyahemavathy, R., additional, Sriraman, Archana, additional, Sarvanabhavan, Anuradha, additional, Manickavasagam, Punithavathy, additional, Simon, Anna, additional, Aggarwal, Indira, additional, Moses, Prabhakar D., additional, Arora, Rashmi, additional, and Kang, Gagandeep, additional

Published
2018
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24. Validation of the children's depression rating scale- revised for adolescents in primary-care pediatric use in India

Author

Basker, Mona, Russell, Paul, Russell, Sushila, and Moses, Prabhakar

Subjects
Pediatrics -- Psychological aspects, Child psychopathology -- Research -- Psychological aspects, Depression, Mental -- Research -- Psychological aspects, Health, Science and technology
Abstract

Byline: Mona. Basker, Paul. Russell, Sushila. Russell, Prabhakar. Moses Background: Adolescent depression needs to be identified and treated in the primary care settings. There is no clinician-rated measure validated in [...]

Published
2010

25. The duration of intestinal immunity after an inactivated poliovirus vaccine booster dose in children immunized with oral vaccine: a randomized controlled trial

Author

John, Jacob, Giri, Sidhartha, Karthikeyan, Arun S, Lata, Dipti, Jeyapaul, Shalini, Rajan, Anand K, Kumar, Nirmal, Dhanapal, Pavithra, Venkatesan, Jayalakshmi, Mani, Mohanraj, Hanusha, Janardhanan, Raman, Uma, Moses, Prabhakar D, Abraham, Asha, Bahl, Sunil, Bandyopadhyay, Ananda S, Ahmad, Mohammad, Grassly, Nicholas C, and Kang, Gagandeep

Subjects
Male, Immunology, Dose-Response Relationship, Immunologic, Immunization, Secondary, Antibodies, Viral, Microbiology, human challenge, Feces, Major Article, Humans, Immunity, Mucosal, Immunization Schedule, Science & Technology, poliovirus, Vaccination, Infant, inactivated vaccine, 11 Medical And Health Sciences, 06 Biological Sciences, OPEN-LABEL, Antibodies, Neutralizing, Virus Shedding, Intestines, Poliovirus Vaccine, Inactivated, Treatment Outcome, Infectious Diseases, Child, Preschool, Poliovirus Vaccine, Oral, MUCOSAL IMMUNITY, Female, INDIA, oral vaccine, Life Sciences & Biomedicine, Poliomyelitis
Abstract

Background In 2014, 2 studies showed that inactivated poliovirus vaccine (IPV) boosts intestinal immunity in children previously immunized with oral poliovirus vaccine (OPV). As a result, IPV was introduced in mass campaigns to help achieve polio eradication. Methods We conducted an open-label, randomized, controlled trial to assess the duration of the boost in intestinal immunity following a dose of IPV given to OPV-immunized children. Nine hundred healthy children in Vellore, India, aged 1–4 years were randomized (1:1:1) to receive IPV at 5 months (arm A), at enrollment (arm B), or no vaccine (arm C). The primary outcome was poliovirus shedding in stool 7 days after bivalent OPV challenge at 11 months. Results For children in arms A, B, and C, 284 (94.7%), 297 (99.0%), and 296 (98.7%), respectively, were eligible for primary per-protocol analysis. Poliovirus shedding 7 days after challenge was less prevalent in arms A and B compared with C (24.6%, 25.6%, and 36.4%, respectively; risk ratio 0.68 [95% confidence interval: 0.53–0.87] for A versus C, and 0.70 [0.55–0.90] for B versus C). Conclusions Protection against poliovirus remained elevated 6 and 11 months after an IPV boost, although at a lower level than reported at 1 month. Clinical Trials Registration CTRI/2014/09/004979.

Published
2016

26. Paraneoplastic papilloedema in a child with neuroblastoma

Author

Scott, Julius, Moses, Prabhakar, Somashekar, H., and Kumar, T. Sathish

Subjects
Neuroblastoma -- Risk factors, Neuroblastoma -- Diagnosis, Neuroblastoma -- Care and treatment, Neuroblastoma -- Patient outcomes, Neuroblastoma -- Case studies, Paraneoplastic syndromes -- Risk factors, Paraneoplastic syndromes -- Diagnosis, Paraneoplastic syndromes -- Care and treatment, Paraneoplastic syndromes -- Patient outcomes, Paraneoplastic syndromes -- Case studies
Abstract

Byline: Julius. Scott, Prabhakar. Moses, H. Somashekar, T. Sathish Kumar Non-metastatic neurological disease complicating neuroblastoma is well recognized. Gross papilloedema in the absence of intracranial disease as initial manifestation of [...]

Published
2005

27. Multidrug-resistant Streptococcus pneumoniae from India

Author

Moses, Prabhakar D, Brahmdathan, K N, Thomas, Kurien, Pai, Rekha, Lalitha, M K, Manoharan, Anand, and Appelbaum, PC

Subjects
Streptococcus pneumoniae, Drug resistance in microorganisms -- India, India -- Health aspects
Published
2002

29. The duration of intestinal immunity after an inactivated poliovirus vaccine booster dose in children immunized with oral vaccine: a randomised controlled trial

Author

John, Jacob, primary, Giri, Sidhartha, additional, Karthikeyan, Arun S, additional, Lata, Dipti, additional, Jeyapaul, Shalini, additional, Rajan, Anand K, additional, Kumar, Nirmal, additional, Dhanapal, Pavithra, additional, Jayalakshmi, V., additional, Mohanraj, M, additional, Hanusha, J, additional, Raman, Uma, additional, Moses, Prabhakar D, additional, Abraham, Asha, additional, Bahl, Sunil, additional, Bandyopadhyay, Ananda S., additional, Ahmad, Mohammad, additional, Grassly, Nicholas C, additional, and Kang, Gagandeep, additional

Published
2016
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35. Estimation of the Burden of Pandemic(H1N1)2009 in Developing Countries: Experience from a Tertiary Care Center in South India

Author

Moorthy, Mahesh, primary, Samuel, Prasanna, additional, Peter, John Victor, additional, Vijayakumar, Saranya, additional, Sekhar, Dipika, additional, Verghese, Valsan P., additional, Agarwal, Indira, additional, Moses, Prabhakar D., additional, Ebenezer, Kala, additional, Abraham, Ooriapadickal Cherian, additional, Thomas, Kurien, additional, Mathews, Prasad, additional, Mishra, Akhilesh C., additional, Lal, Renu, additional, Muliyil, Jayaprakash, additional, and Abraham, Asha Mary, additional

Published
2012
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37. Multisite Study of Cryptosporidiosis in Children with Diarrhea in India

Author

Ajjampur, Sitara Swarna Rao, primary, Liakath, Farzana Begum, additional, Kannan, Arun, additional, Rajendran, Priya, additional, Sarkar, Rajiv, additional, Moses, Prabhakar Devarajan, additional, Simon, Anna, additional, Agarwal, Indira, additional, Mathew, Ann, additional, O'Connor, Roberta, additional, Ward, Honorine, additional, and Kang, Gagandeep, additional

Published
2010
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39. Nitric oxide production in acute gastroenteritis in Indian children

Author

Sowmyanarayanan, Thuppal Varadachari, primary, Natarajan, Sathish Kumar, additional, Ramachandran, Anup, additional, Sarkar, Rajiv, additional, Moses, Prabhakar Devarajan, additional, Simon, Anna, additional, Agarwal, Indira, additional, Christopher, Solomon, additional, and Kang, Gagandeep, additional

Published
2009
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42. Comparative Study of the Epidemiology of Rotavirus in Children from a Community-Based Birth Cohort and a Hospital in South India

Author

Banerjee, Indrani, primary, Ramani, Sasirekha, additional, Primrose, Beryl, additional, Moses, Prabhakar, additional, Iturriza-Gomara, Miren, additional, Gray, James J., additional, Jaffar, Shabbar, additional, Monica, Bindhu, additional, Muliyil, Jaya Prakash, additional, Brown, David W., additional, Estes, Mary K., additional, and Kang, Gagandeep, additional

Published
2006
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44. Quantitation of group A rotavirus by real-time reverse-transcription-polymerase chain reaction: Correlation with clinical severity in children in South India

Author

Kang, Gagandeep, primary, Iturriza-Gomara, Miren, additional, Wheeler, Jeremy G., additional, Crystal, Premila, additional, Monica, Bindhu, additional, Ramani, Sasirekha, additional, Primrose, Beryl, additional, Moses, Prabhakar D., additional, Gallimore, Chris I., additional, Brown, David W., additional, and Gray, Jim, additional

Published
2004
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48. Diversity of circulating rotavirus strains in children hospitalized with diarrhea in India, 2005–2009.

Author

Kang, Gagandeep, Desai, Rishi, Arora, Rashmi, Chitamabar, Shobha, Naik, Trilok Nath, Krishnan, Triveni, Deshpande, Jagdish, Gupte, Mohan D., S. Venkatasubramaniam, Gentsch, Jon R., Parashar, Umesh D., Mathew, Ann, Anita, Sr., Ramani, Sasirekha, Sowmynarayanan, Thuppal V., Moses, Prabhakar D., Agarwal, Indira, Simon, Anna, Bose, Anuradha, and Arora, Ritu

Subjects
*BIODIVERSITY, *SPECIES diversity, *ROTAVIRUSES, *HOSPITAL care of children, *DIARRHEA in children, *FECES examination, *DETECTION of microorganisms, *THERAPEUTICS
Abstract

Highlights: [•] 2899 (40%) out of 7285 stool samples were rotavirus positive from 2005 to 2009. [•] G12 infections rose to 39% in Northern India and to 24% in the Western India. [•] 8% of rotavirus detections had multiple G-types and 3% had multiple P-types. [ABSTRACT FROM AUTHOR]

Published
2013
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49. Ocular manifestations of Behcet's disease.

Author

A SE, Moses PD, and George R

Subjects
Behcet Syndrome diagnosis, Behcet Syndrome immunology, Behcet Syndrome therapy, Child, Eye Diseases diagnosis, Eye Diseases therapy, Glucocorticoids therapeutic use, HLA-B Antigens, Histocompatibility Testing, Humans, Male, Oral Ulcer etiology, Skin Ulcer etiology, Treatment Outcome, Behcet Syndrome complications, Eye Diseases etiology
Abstract

Behcets disease is a systemic inflammatory vascular disorder characterized by recurrent oral and genital ulcers, eye lesion, arthritis and skin lesions. We report a case of Behcets disease with ocular manifestation in an 8 year old boy.

Published
2005

50. Scrub typhus.

Author

Pavithran S, Mathai E, and Moses PD

Subjects
Anti-Bacterial Agents therapeutic use, Child, Doxycycline therapeutic use, Female, Humans, Scrub Typhus drug therapy, Scrub Typhus diagnosis
Abstract

Scrub typhus is being increasingly reported in adults in India. It should be considered a strong possibility in all undifferentiated fevers. Two children with this infection are being reported highlighting the wide variation in clinical presentation. Specific tests should be preferred over Weil Felix test wherever possible especially in areas reporting a high incidence of the infection.

Published
2004

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