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2. Incidence patterns of childhood non-Wilms renal tumors: Comparing data of the Nationwide Registry of Childhood Hematological Malignancies and Solid Tumors (NARECHEM-ST), Greece, and the Surveillance, Epidemiology, and End Results Program (SEER), USA

Author

Moschovi, Maria, Antoniad, Kondilia, Polychronopoulou, Sofia, Papakonstantinou, Eugenia, Tragiannidis, Athanasios, Vasileiou, Eleni, Katzilakis, Nikolaos, Pelagiadis, Iordanis, Dana, Helen, Stefanaki, Kalliopi, Strantzia, Katerina, Gavra, Maria, Alexopoulou, Aikaterini, Doganis, Dimitrios, Karalexi, Maria A., Panagopoulou, Paraskevi, Bouka, Panagiota, Bouka, Evdoxia, Markozannes, Georgios, Ntzani, Evangelia E., Steliarova-Foucher, Eva, and Petridou, Eleni Th.

Published
2022
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3. Complexities of Management of Atypical Ventricular Fibrillation Storm in a Young Patient With TANGO2.

Author

Gonzalez Corcia, M. Cecilia, Bradshaw, Catherine, Chronopoulou, Efstathia, Shortland, Jennifer, O'Sullivan, Benjamin, Murphy, Tim, and Moschovi, Maria

Subjects
VENTRICULAR arrhythmia, VENTRICULAR fibrillation, EXTRACORPOREAL membrane oxygenation, GENETIC disorders, THERAPEUTICS
Abstract

TANGO2 deficiency disorder, a rare autosomal recessive genetic disorder characterised by biallelic loss‐of‐function variants in the TANGO2 gene, was first described in 2016. This disorder involves the transport and Golgi organisation homologue, impacting Golgi membrane redistribution into the endoplasmic reticulum. Clinically, affected individuals exhibit a multiorgan phenotype, with prominent neurological manifestations such as developmental delay and regression. Metabolic crises, triggered by minor infections or fasting, are a hallmark of the disorder. We present the case of a 5‐year‐old boy diagnosed with TANGO2 deficiency disorder who experienced a refractory‐to‐treatment ventricular arrhythmia storm. The patient's clinical course was marked by rhabdomyolysis‐induced muscle pain, weakness and dark urine. Despite aggressive medical management during intercurrent illness, including hyperhydration, maintenance of normoglycemia and correction of electrolyte abnormalities, the patient's condition deteriorated, leading to a life‐threatening ventricular arrhythmia storm. In a life‐saving therapeutic approach, the patient underwent a thoracoscopic left sympathectomy during extracorporeal membrane oxygenation (ECMO) support. Remarkably, this intervention resulted in the termination of the ventricular arrhythmia storm. The case underscores the challenges in managing TANGO2 deficiency disorder‐associated complications and highlights the potential role of innovative interventions, such as sympathectomy during ECMO, in critical and refractory cases. This case contributes to the understanding of the clinical spectrum of TANGO2 deficiency disorder and emphasises the need for further research into targeted therapies for this rare metabolic condition, where current treatment strategies focus on symptom management. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Maternal lifestyle factors and risk of neuroblastoma in the offspring: A meta-analysis including Greek NARECHEM-ST primary data

Author

Servitzoglou, Marina, Baka, Margarita, Moschovi, Maria, Kourti, Maria, Papadakis, Vassilios, Polychronopoulou, Sofia, Hatzipantelis, Emmanouel, Ioannidou, Maria, Dana, Helen, Pelagiadis, Iordanis, Stiakaki, Eftichia, Stefanaki, Kalliopi, Strantzia, Katerina, Gavra, Maro, Malama, Astero, Mitsios, Andreas, Bouka, Evdoxia, Karalexi, Maria A, Katsimpris, Andreas, Panagopoulou, Paraskevi, Bouka, Panagiota, Schüz, Joachim, Ntzani, Evangelia, and Petridou, Eleni Th

Published
2022
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5. Survival and prognostic factors for childhood malignant liver tumors: analysis of harmonized clinical data

Author

Antoniadi, Kondilia, Baka, Margaret, Dana, Helen, Gavra, Maria, Hatzipantelis, Emmanuel, Kourti, Maria, Malama, Astero, Papaconstantinou, Evgenia, Pelagiadis, Iordanis, Polychronopoulou, Sofia, Stefanaki, Kalliopi, Steiakaki, Eftichia, Strantzia, Katerina, Akhaladze, Dmitry, Filin, Andrey, Varfolomeeva, Svetlana, Karalexi, Maria A., Servitzoglou, Marina, Moschovi, Maria, Moiseenko, Roman, Bouka, Panagiota, Ntzani, Evangelia, Kachanov, Denis, and Petridou, Eleni Th.

Published
2021
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6. Maternal lifestyle characteristics and Wilms tumor risk in the offspring: A systematic review and meta-analysis

Author

Doganis, Dimitrios, Katsimpris, Andreas, Panagopoulou, Paraskevi, Bouka, Panagiota, Bouka, Evdoxia, Moschovi, Maria, Polychronopoulou, Sofia, Papakonstantinou, Evgenia, Tragiannidis, Athanasios, Katzilakis, Nick, Dana, Helen, Antoniadi, Kondilia, Stefanaki, Kalliopi, Strantzia, Katerina, Dessypris, Nick, Schüz, Joachim, and Petridou, Eleni Th.

Published
2020
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7. Age-, sex- and disease subtype–related foetal growth differentials in childhood acute myeloid leukaemia risk: A Childhood Leukemia International Consortium analysis

Author

Baka, Margarita, Moschovi, Maria, Polychronopoulou, Sophia, Kourti, Maria, Hatzipantelis, Emmanuel, Pelagiadis, Iordanis, Dana, Helen, Kantzanou, Maria, Tzanoudaki, Marianna, Anastasiou, Theodora, Grenzelia, Maria, Gavriilaki, Eleni, Sakellari, Ioanna, Anagnostopoulos, Achilles, Kitra, Vassiliki, Paisiou, Anna, Bouka, Evdoxia, Nikkilä, Atte, Lohi, Olli, Karalexi, Maria A., Dessypris, Nick, Ma, Xiaomei, Spector, Logan G., Marcotte, Erin, Clavel, Jacqueline, Pombo-de-Oliveira, Maria S., Heck, Julia E., Roman, Eve, Mueller, Beth A., Hansen, Johnni, Auvinen, Anssi, Lee, Pei-Chen, Schüz, Joachim, Magnani, Corrado, Mora, Ana M., Dockerty, John D., Scheurer, Michael E., Wang, Rong, Bonaventure, Audrey, Kane, Eleanor, Doody, David R., Erdmann, Friederike, Kang, Alice Y., Metayer, Catherine, Milne, Elizabeth, and Petridou, Eleni Th

Published
2020
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8. Wilms tumour event-free and overall survival in Southern and Eastern Europe: Pooled analyses of clinical data from four childhood cancer registries (1999–2017)

Author

Doganis, Dimitrios, Zborovskaya, Anna, Trojanowski, Maciej, Zagar, Tina, Bouka, Panagiota, Baka, Margaret, Moschovi, Maria, Polychronopoulou, Sofia, Papakonstantinou, Eugenia, Tragiannidis, Athanasios, Stiakaki, Eftichia, Dana, Helen, Stefanaki, Kalliopi, Strantzia, Katerina, Kochubinsky, Dmitry, Marciniak, Patrycja, Avcin, Simona, Antoniadi, Kondilia, Dessypris, Nick, and Petridou, Eleni Th.

Published
2019
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9. Perinatal and early life risk factors for childhood brain tumors: Is instrument-assisted delivery associated with higher risk?

Author

Bourgioti, Charis, Dana, Helen, Papadopoulos, Savvas, Sfakianos, Georgios, Themistocleous, Marios, Stefanaki, Kalliopi, Strantzia, Katerina, Zountsas, Basilios, Vakis, Antonios, Manolitsi, Katerina, Kelekis, Nikolaos, Papathanasiou, Mathilda, Gkantaifi, Areti, Koutzoglou, Michalis, Koletsa, Triantafyllia, Nikas, Ioannis, Zacharoulis, Stergios, Prassopoulos, Panagiotis, Orfanides, George, Panagiotis, Primikiris, Zerris, Vasilios, Friehs, Gerhard, Vyziotis, Alex, Patsouris, Eustratios, Georgakis, Marios K., Dessypris, Nick, Papadakis, Vassilios, Tragiannidis, Athanasios, Bouka, Evdoxia, Hatzipantelis, Emmanuel, Moschovi, Maria, Papakonstantinou, Evgenia, Polychronopoulou, Sophia, Sgouros, Spyridon, Stiakaki, Eftichia, Pourtsidis, Apostolos, Psaltopoulou, Theodora, and Petridou, Eleni Th.

Published
2019
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10. Preductal Hemodynamic Redistribution in Preterm Infants with Patent Ductus Arteriosus.

Author

Surak, Aimann and Moschovi, Maria

Subjects
*PATENT ductus arteriosus, *BRACHIOCEPHALIC trunk, *PREMATURE infants, *HEMODYNAMICS
Abstract

A patent ductus arteriosus is a common entity in preterm infants. Literature is lacking regarding physiological effects on preductal circulation. This report describes 3 patients with abnormal flow Doppler pattern in brachiocephalic artery. Further research is warranted to better understand the impact of PDA on preductal circulation. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Survival and mortality rates of Wilms tumour in Southern and Eastern European countries: Socioeconomic differentials compared with the United States of America

Author

Doganis, Dimitrios, Panagopoulou, Paraskevi, Tragiannidis, Athanasios, Vichos, Theodoros, Moschovi, Maria, Polychronopoulou, Sofia, Rigatou, Efthimia, Papakonstantinou, Eugenia, Stiakaki, Eftichia, Dana, Helen, Bouka, Panagiota, Antunes, Luis, Bastos, Joana, Coza, Daniela, Demetriou, Anna, Agius, Domenic, Eser, Sultan, Ryzhov, Anton, Sekerija, Mario, Trojanowski, Maciej, Zagar, Tina, Zborovskaya, Anna, Perisic, Snezana Zivkovic, Strantzia, Katerina, Dessypris, Nick, Psaltopoulou, Theodora, and Petridou, Eleni Th

Published
2018
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12. Childhood nephroblastoma in Southern and Eastern Europe and the US: Incidence variations and temporal trends by human development index

Author

Doganis, Dimitrios, Panagopoulou, Paraskevi, Tragiannidis, Athanasios, Georgakis, Marios K., Moschovi, Maria, Polychronopoulou, Sofia, Rigatou, Efthimia, Papakonstantinou, Eugenia, Stiakaki, Eftichia, Dana, Helen, Bouka, Evdoxia, Antunes, Luis, Bastos, Joana, Coza, Daniela, Demetriou, Anna, Agius, Domenic, Eser, Sultan, Ryzhov, Anton, Sekerija, Mario, Trojanowski, Maciej, Zagar, Tina, Zborovskaya, Anna, Perisic, Snezana Zivkovic, Stefanaki, Kalliopi, Dessypris, Nick, and Petridou, Eleni Th.

Published
2018
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13. Persisting inequalities in survival patterns of childhood neuroblastoma in Southern and Eastern Europe and the effect of socio-economic development compared with those of the US

Author

Panagopoulou, Paraskevi, Georgakis, Marios K., Baka, Margarita, Moschovi, Maria, Papadakis, Vassilios, Polychronopoulou, Sophia, Kourti, Maria, Hatzipantelis, Emmanuel, Stiakaki, Eftichia, Dana, Helen, Tragiannidis, Athanasios, Bouka, Evdoxia, Antunes, Luis, Bastos, Joana, Coza, Daniela, Demetriou, Anna, Agius, Domenic, Eser, Sultan, Gheorghiu, Raluca, Šekerija, Mario, Trojanowski, Maciej, Žagar, Tina, Zborovskaya, Anna, Ryzhov, Anton, Dessypris, Nick, Morgenstern, Daniel, and Petridou, Eleni Th

Published
2018
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17. Anthropometrics at birth and risk of a primary central nervous system tumour: A systematic review and meta-analysis

Author

Moschovi, Maria, Pourtsidis, Apostolos, Polychronopoulou, Sophia, Hatzipantelis, Emmanuel, Papakonstantinou, Evgenia, Dana, Helen, Stiakaki, Eftichia, Bouka, Evdoxia, Stefanaki, Kalliopi, Sgouros, Spyros, Patsouris, Eustratios, Papadopoulos, Savvas, Strantzia, Katerina, Zountsas, Basilios, Vakis, Antonios, Kelekis, Nikolaos, Sfakianos, Georgios, Chatziioannou, Achilles, Sidi, Vasiliki, Koutzoglou, Michael, Nikolaou, Filippia, Zacharoulis, Stergios, Georgakis, Marios K., Kalogirou, Eleni I., Liaskas, Athanasios, Karalexi, Maria A., Papathoma, Paraskevi, Ladopoulou, Kyriaki, Kantzanou, Maria, Tsivgoulis, Georgios, and Petridou, Eleni Th.

Published
2017
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18. Survival trends in childhood chronic myeloid leukaemia in Southern-Eastern Europe and the United States of America

Author

Karalexi, Maria A., Baka, Margarita, Ryzhov, Anton, Zborovskaya, Anna, Dimitrova, Nadya, Zivkovic, Snezana, Eser, Sultan, Antunes, Luis, Sekerija, Mario, Zagar, Tina, Bastos, Joana, Demetriou, Anna, Agius, Domenic, Florea, Margareta, Coza, Daniela, Polychronopoulou, Sophia, Stiakaki, Eftichia, Moschovi, Maria, Hatzipantelis, Emmanuel, Kourti, Maria, Graphakos, Stelios, Pombo-de-Oliveira, Maria S., Adami, Hans Olov, and Petridou, Eleni Th.

Published
2016
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19. Incidence and time trends of childhood lymphomas : findings from 14 Southern and Eastern European cancer registries and the Surveillance, Epidemiology and End Results, USA

Author

Georgakis, Marios K., Karalexi, Maria A., Agius, Domenic, Antunes, Luis, Bastos, Joana, Coza, Daniela, Demetriou, Anna, Dimitrova, Nadya, Eser, Sultan, Florea, Margareta, Ryzhov, Anton, Sekerija, Mario, Žagar, Tina, Zborovskaya, Anna, Zivkovic, Snezana, Bouka, Evdoxia, Kanavidis, Prodromos, Dana, Helen, Hatzipantelis, Emmanuel, Kourti, Maria, Moschovi, Maria, Polychronopoulou, Sophia, Stiakaki, Eftichia, Kantzanou, Maria, Pourtsidis, Apostolos, and Petridou, Eleni Th.

Published
2016

20. INTERVENTIONS FOR CANCER PAIN MANAGEMENT IN CHILDREN UNDERGOING THERAPY: SYSTEMATIC REVIEW

Author

Papamihali, Anastasia, Moschovi, Maria, Koutelekos, Ioannis, and Dousis, Evangelos

Subjects
Cancer pain, pediatric, nursing, therapy, cancer
Abstract

Introduction: Cancer is the second leading cause of death in children according to the American Cancer Society. Treatment may include chemotherapy, surgery, or radiation therapy, either alone or in combination. One of the most well-known effects of chemotherapy in children is pain, which has a negative effect on their physical and mental health and on the progress of the treatment. The aim of the present study was to investigate the application of the interventions for the management of pain in children with cancer undergoing treatment. Methodology: This is a systematic literature review carried out by searching for articles in international bibliographic databases (Medline (via PubMed) Scopus & Cochrane Library) for the period 2003-2022. The criteria for inclusion of an article in the study were: it must be written in English, it must be completely relevant to the topic, its sample to concern children or adolescents or young adults with cancer under treatment, it must be published in a valid scientific journal, and to concern quantitative study. After a systematic and critical evaluation of the articles, 8 articles were included in the study. Results: Studies have shown that using digital pain management apps, foot massage, cognitive (educational) intervention, daily journaling, painting and talking, and reiki can improve cancer pain management to the children. Conclusions: The literature review revealed that more studies with stronger research designs are needed to investigate pain management interventions in children with cancer. Healthcare professionals can use the results of this study to design better healthcare for children with cancer.

Published
2023
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21. Prelabor cesarean delivery and early-onset acute childhood leukemia risk

Author

Thomopoulos, Thomas P., Skalkidou, Alkistis, Dessypris, Nick, Chrousos, George, Karalexi, Maria A., Karavasilis, Theodoros G., Baka, Margarita, Hatzipantelis, Emmanuel, Kourti, Maria, Polychronopoulou, Sophia, Sidi, Vasiliki, Stiakaki, Eftichia, Moschovi, Maria, Loutradis, Dimitrios, and Petridou, Eleni Th.

Published
2016

22. Psychosocial adaptation of families with children newly diagnosed with cancer in the Greek population amidst the socioeconomic crisis.

Author

I.Vlachos, Ιlias, Ktena, Yiouli, Athanasiadou, Anastasia, Charmandari, Evangelia, and Moschovi, Maria

Subjects
DIAGNOSIS of tumors in children, MENTAL depression risk factors, STATE-Trait Anxiety Inventory, PSYCHOLOGY of parents, SCIENTIFIC observation, RECESSIONS, CHILDREN'S hospitals, FAMILY support, QUANTITATIVE research, PSYCHOLOGICAL tests, RISK assessment, QUESTIONNAIRES, DESCRIPTIVE statistics, PSYCHOLOGICAL adaptation, ANXIETY, LONGITUDINAL method, FAMILY structure
Abstract

To present the initial assessment of psychosocial adaptation among Greek parents whose children were newly diagnosed with cancer amidst the turmoil of an ongoing financial crisis. This prospective observational study used a quantitative approach. Sixty-one parents of children with cancer treated at a large urban tertiary-care children's hospital were prospectively recruited to participate in our study during the first week of their child's diagnosis (2013–2016). The parents were asked to complete the psychosocial assessment tool (PAT 2.0), Zung Depression Scale, State-Trait Anxiety Inventory, Hospital Anxiety and Depression Scale, and World Health Organization Quality of Life–Bref Instrument; Moreover, three female healthcare providers (the physician oncologist, the head nurse and a senior nurse) completed the relevant PAT 2.0 -Staff Perceptions questionnaire the results of which were then compared to those of the child's parent. The majority of parents had PAT 2.0 scores indicative of increased psychosocial risk :54% were stratified into the "Targeted" (moderate risk) and 15% into the "Clinical" (highest risk) categories, whereas healthcare providers underestimated psychosocial risk in 57%−59% of the cases. The subscales that most contributed to the increased scores were Parental Stress Reaction, Family Structure and Resources, and Family Social Support. The PAT 2.0 had statistically significant correlations with most of the anxiety and depression scales, with Zung having the strongest correlation (r-value: +0.5, p-value <0.01). Our cohort presented more anxiety and depression compared to the general Greek population (14% for depression versus 2,9% for the general population and 46% for anxiety compared to 4,1%) in the years of financial recession in Greece. The parents of children newly diagnosed with cancer in Greece are at increased risk for developing anxiety and depression in the years of financial recession in Greece compared to general population. Parental stress reaction to diagnosis as well as lack of family resources and social support may contribute to this difference. Screening for psychosocial risk factors is essential for the early identification of these families and for the optimal utilization of the limited available resources in times of economic hardship. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Childhood central nervous system tumour mortality and survival in Southern and Eastern Europe (1983–2014): Gaps persist across 14 cancer registries

Author

Karalexi, Maria A., Papathoma, Paraskevi, Thomopoulos, Thomas P., Ryzhov, Anton, Zborovskaya, Anna, Dimitrova, Nadya, Zivkovic, Snezana, Eser, Sultan, Antunes, Luís, Sekerija, Mario, Zagar, Tina, Bastos, Joana, Demetriou, Anna, Agius, Domenic, Cozma, Raluca, Coza, Daniela, Bouka, Evdoxia, Dessypris, Nick, Belechri, Maria, Dana, Helen, Hatzipantelis, Emmanuel, Papakonstantinou, Evgenia, Polychronopoulou, Sophia, Pourtsidis, Apostolos, Stiakaki, Eftichia, Chatziioannou, Achilles, Manolitsi, Katerina, Orphanidis, Georgios, Papadopoulos, Savvas, Papathanasiou, Mathilda, Patsouris, Eustratios, Sgouros, Spyros, Zountsas, Basilios, Moschovi, Maria, Steliarova-Foucher, Eva, and Petridou, Eleni Th.

Published
2015
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28. Childhood central nervous system tumours: Incidence and time trends in 13 Southern and Eastern European cancer registries

Author

Papathoma, Paraskevi, Thomopoulos, Thomas P., Karalexi, Maria A., Ryzhov, Anton, Zborovskaya, Anna, Dimitrova, Nadya, Zivkovic, Snezana, Eser, Sultan, Antunes, Luís, Sekerija, Mario, Zagar, Tina, Bastos, Joana, Demetriou, Anna, Cozma, Raluca, Coza, Daniela, Bouka, Evdoxia, Dessypris, Nick, Kantzanou, Maria, Kanavidis, Prodromos, Dana, Helen, Hatzipantelis, Emmanuel, Moschovi, Maria, Polychronopoulou, Sophia, Pourtsidis, Apostolos, Stiakaki, Eftichia, Papakonstantinou, Evgenia, Oikonomou, Konstantinos, Sgouros, Spyros, Vakis, Antonios, Zountsas, Basilios, Bourgioti, Charis, Kelekis, Nikolaos, Prassopoulos, Panos, Choreftaki, Theodosia, Papadopoulos, Savvas, Stefanaki, Kalliopi, Strantzia, Katerina, Cardis, Elisabeth, Steliarova-Foucher, Eva, and Petridou, Eleni Th.

Published
2015
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30. Maternal Supplementation with Folic Acid and Other Vitamins and Risk of Leukemia in Offspring: A Childhood Leukemia International Consortium Study

Author

Metayer, Catherine, Milne, Elizabeth, Dockerty, John D., Clavel, Jacqueline, Pombo-de-Oliveira, Maria S., Wesseling, Catharina, Spector, Logan G., Schüz, Joachim, Petridou, Eleni, Ezzat, Sameera, Armstrong, Bruce K., Rudant, Jérémie, Koifman, Sergio, Kaatsch, Peter, Moschovi, Maria, Rashed, Wafaa M., Selvin, Steve, McCauley, Kathryn, Hung, Rayjean J., Kang, Alice Y., and Infante-Rivard, Claire

Published
2014

31. Parental occupational paint exposure and risk of childhood leukemia in the offspring: findings from the Childhood Leukemia International Consortium

Author

Bailey, Helen D., Fritschi, Lin, Metayer, Catherine, Infante-Rivard, Claire, Magnani, Corrado, Petridou, Eleni, Roman, Eve, Spector, Logan G., Kaatsch, Peter, Clavel, Jacqueline, Milne, Elizabeth, Dockerty, John D., Glass, Deborah C., Lightfoot, Tracy, Miligi, Lucia, Rudant, Jérémie, Baka, Margarita, Rondelli, Roberto, Amigou, Alicia, Simpson, Jill, Kang, Alice Y., Moschovi, Maria, and Schüz, Joachim

Published
2014

32. Incidence, time trends and survival patterns of childhood pilocytic astrocytomas in Southern-Eastern Europe and SEER, US

Author

Georgakis, Marios K., Karalexi, Maria A., Kalogirou, Eleni I., Ryzhov, Anton, Zborovskaya, Anna, Dimitrova, Nadya, Eser, Sultan, Antunes, Luis, Sekerija, Mario, Zagar, Tina, Bastos, Joana, Agius, Domenic, Florea, Margareta, Coza, Daniela, Bouka, Evdoxia, Bourgioti, Charis, Dana, Helen, Hatzipantelis, Emmanuel, Moschovi, Maria, Papadopoulos, Savvas, Sfakianos, Georgios, Papakonstantinou, Evgenia, Polychronopoulou, Sophia, Sgouros, Spyros, Stefanaki, Kalliopi, Stiakaki, Eftichia, Strantzia, Katerina, Zountsas, Basilios, Pourtsidis, Apostolos, Patsouris, Eustratios, and Petridou, Eleni Th.

Published
2017
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33. Wireless phones and brain tumour risk in young people: results of the multi-national MOBI-Kids study

Author

Castaño-Vinyals, Gemma, primary, Sadetzki, Siegal, additional, Vermeulen, Roel, additional, Momoli, Franco, additional, Kundi, Michael, additional, Merletti, Franco, additional, Maslanyj, Myron, additional, Calderón, Carolina, additional, Wiart, Joe, additional, Lee, Ae-Kyoung, additional, Taki, Masao, additional, Sim, Malcom, additional, Armstrong, Bruce, additional, Benke, Geza, additional, Schattner, Rosa, additional, Hutter, Hans-Peter, additional, Krewski, Dan, additional, Mohipp, Charmaine, additional, Ritvo, Paul, additional, Spinelli, John, additional, Lacour, Brigitte, additional, Remen, Thomas, additional, Radon, Katja, additional, Weinmann, Tobias, additional, Petridou, Eleni Th, additional, Moschovi, Maria, additional, Pourtsidis, Apostolos, additional, Oikonomou, Kyriakos, additional, Kanavidis, Prodromos, additional, Bouka, Evi, additional, Dikshit, Rajesh, additional, Nagrani, Rajni, additional, Chetrit, Angela, additional, Bruchim, Revital, additional, Maule, Milena, additional, Migliore, Enrica, additional, Filippini, Gabriella, additional, Miligi, Lucia, additional, Mattioli, Stefano, additional, Kojimahara, Noriko, additional, Yamaguchi, Naohito, additional, Ha, Mina, additional, Choi, K, additional, Kromhout, Hans, additional, Goedhart, Geertje, additional, ‘t Mannetje, Andrea, additional, Eng, Amanda, additional, Langer, Chelsea Eastman, additional, Alguacil, Juan, additional, Aragonés, Nuria, additional, Morales-Suárez-Varela, Maria, additional, Badia, Francesc, additional, Albert, Alex, additional, Carretero, Gema, additional, and Cardis, Elisabeth, additional

Published
2022
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36. Childhood leukemia and lymphoma: time trends and factors affecting survival in five Southern and Eastern European Cancer Registries

Author

Petridou, Eleni Th., Dimitrova, Nadya, Eser, Sultan, Kachanov, Denis, Karakilinc, Hulya, Varfolomeeva, Svetlana, Belechri, Maria, Baka, Margarita, Moschovi, Maria, Polychronopoulou, Sofia, Athanasiadou-Piperopoulou, Fani, Fragandrea, Ioanna, Stiakaki, Eftichia, Pourtsidis, Apostolos, Stefanadis, Christodoulos, Coebergh, Jan-Willem, and Sergentanis, Theodoros N.

Published
2013

38. Survival patterns of childhood neuroblastoma: an analysis of clinical data from Southern-Eastern European countries.

Author

Karalexi, Maria A., Servitzoglou, Marina, Papadakis, Vassilios, Kachanov, Denis, Česen Mazič, Maja, Baka, Margaret, Moschovi, Maria, Kourti, Maria, Polychronopoulou, Sofia, Stiakaki, Eftichia, Hatzipantelis, Emmanuel, Dana, Helen, Stefanaki, Kalliopi, Malama, Astero, Themistocleous, Marios S., Strantzia, Katerina, Shamanskaya, Tatyana, Bouka, Panagiota, Panagopoulou, Paraskevi, and Kantzanou, Maria

Published
2023
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40. Incidence patterns of childhood non-Wilms renal tumors: Comparing data of the Nationwide Registry of Childhood Hematological Malignancies and Solid Tumors (NARECHEM-ST), Greece, and the Surveillance, Epidemiology, and End Results Program (SEER), USA

Author

Doganis, Dimitrios, primary, Karalexi, Maria A., additional, Panagopoulou, Paraskevi, additional, Bouka, Panagiota, additional, Bouka, Evdoxia, additional, Markozannes, Georgios, additional, Ntzani, Evangelia E., additional, Steliarova-Foucher, Eva, additional, Petridou, Eleni Th., additional, Moschovi, Maria, additional, Antoniad, Kondilia, additional, Polychronopoulou, Sofia, additional, Papakonstantinou, Eugenia, additional, Tragiannidis, Athanasios, additional, Vasileiou, Eleni, additional, Katzilakis, Nikolaos, additional, Pelagiadis, Iordanis, additional, Dana, Helen, additional, Stefanaki, Kalliopi, additional, Strantzia, Katerina, additional, Gavra, Maria, additional, and Alexopoulou, Aikaterini, additional

Published
2022
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42. Maternal lifestyle factors and risk of neuroblastoma in the offspring: A meta-analysis including Greek NARECHEM-ST primary data

Author

Karalexi, Maria A, primary, Katsimpris, Andreas, additional, Panagopoulou, Paraskevi, additional, Bouka, Panagiota, additional, Schüz, Joachim, additional, Ntzani, Evangelia, additional, Petridou, Eleni Th, additional, Servitzoglou, Marina, additional, Baka, Margarita, additional, Moschovi, Maria, additional, Kourti, Maria, additional, Papadakis, Vassilios, additional, Polychronopoulou, Sofia, additional, Hatzipantelis, Emmanouel, additional, Ioannidou, Maria, additional, Dana, Helen, additional, Pelagiadis, Iordanis, additional, Stiakaki, Eftichia, additional, Stefanaki, Kalliopi, additional, Strantzia, Katerina, additional, Gavra, Maro, additional, Malama, Astero, additional, Mitsios, Andreas, additional, and Bouka, Evdoxia, additional

Published
2022
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44. Home pesticide exposures and risk of childhood leukemia: Findings from the childhood leukemia international consortium

Author

Bailey, Helen D., Infante-Rivard, Claire, Metayer, Catherine, Clavel, Jacqueline, Lightfoot, Tracy, Kaatsch, Peter, Roman, Eve, Magnani, Corrado, Spector, Logan G., Th. Petridou, Eleni, Milne, Elizabeth, Dockerty, John D., Miligi, Lucia, Armstrong, Bruce K., Rudant, Jérémie, Fritschi, Lin, Simpson, Jill, Zhang, Luoping, Rondelli, Roberto, Baka, Margarita, Orsi, Laurent, Moschovi, Maria, Kang, Alice Y., and Schüz, Joachim

Published
2015
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49. Overall and event-free survival of childhood lymphoma in Greece: analysis of harmonized clinical data over a 24-year active registration period

Author

Karalexi, Maria A. Pourtsidis, Apostolos Panagopoulou, Paraskevi and Moschovi, Maria Polychronopoulou, Sophia Kourti, Maria and Hatzipantelis, Emmanuel Stiakaki, Eftichia Dana, Helen and Bouka, Panagiota Ntzani, Evangelia E. Petridou, Eleni Th. and NARECHEM-ST Collaborating Grp

Subjects
hemic and lymphatic diseases
Abstract

We assessed event-free (EFS) and overall (OS) survival in 676 incident cases of childhood Hodgkin (HL) and non-Hodgkin (NHL) lymphoma actively registered in Greece (1996-2019). HL-OS5-year was 96% and NHL-OS5-year 85%, whereas HL-EFS5-year was 86% and NHL-EFS5-year was 81%, notably similar to the respective OS rates (HL: 95%, NHL: 85%) in developed countries. For HL, older age at diagnosis, high maternal education and close proximity to treatment centers were linked to remarkably favorable outcomes. By contrast, stage IV patients showed worse OS and EFS. HL patients with low levels of hemoglobin were associated with worse EFS (hazard ratio: 2.81, 95% confidence intervals: 1.09-7.22). OS (76%) and EFS (73%) were poor among high-risk NHL patients and those with increased LDH (71%). The identified predictors of poor disease outcome point to the need for intensification of individualized treatments. Ongoing clinical cancer registration entailing clinical components could contribute to use of state-of-the-art treatments.

Published
2021

50. Low IL-23 levels in peripheral blood and bone marrow at diagnosis of acute leukemia in children increased with the elimination of leukemic burden

Author

Zampogiannis, Archontis Piperi, Christina Baka, Margarita and Zoi, Iliana Papavassiliou, Athanasios G. Moschovi, Maria

Subjects
hemic and lymphatic diseases
Abstract

IL-23 is an IL-12 cytokine family member with pleiotropic functions that regulates tumour growth in various cancer types, exhibiting both anti-tumorigenic and pro-tumorigenic properties. Preclinical studies have shown a potential anti-leukemic action on childhood B-ALL cells. The study involved 65 children with acute leukemia [59 patients with acute lymphoblastic leukemia (ALL) and 6 patients with acute myeloid leukemia (AML)] and 27 healthy controls. Using an enzyme-linked immunosorbent assay, we aimed to determine the IL-23 levels in the peripheral blood (PB) and bone marrow (BM) of patients at diagnosis and at the end of the induction therapy (EIT). PB IL-23 levels were lower in leukemia patients compared to the healthy controls. In all acute leukemia patients, IL-23 levels were significantly lower at diagnosis both in PB (P = .015) and in BM (P = .037) compared to the PB and BM concentrations at the EIT. The same pattern was present in both subgroups of ALL and AML patients. The high leukemic burden at diagnosis was related with lower IL-23 levels, which were increased with the disease remission. Considering the anti-leukemic potential of this cytokine, the elevation of the IL-23 concentration at the disease remission indicates a beneficial role of IL-23 in paediatric acute leukemia.

Published
2021

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