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26 results on '"Moschella, Vincenzo"'

1. Does thyroid diseases contribute to the natural history of idiopathic adult-onset dystonia? Data from the Italian Dystonia Registry

Author

Idrissi, Sarah, Velucci, Vittorio, Esposito, Marcello, Trinchillo, Assunta, Habestwallner, Francesco, Belvisi, Daniele, Fabbrini, Giovanni, Ferrazzano, Gina, Rizzo, Vincenzo, Terranova, Carmen, Girlanda, Paolo, Pellicciari, Roberta, Avanzino, Laura, Di Biasio, Francesca, Marchese, Roberta, Bono, Francesco, Idone, Giovanni, Laterza, Vincenzo, Lettieri, Christian, Rinaldo, Sara, Eleopra, Roberto, Castagna, Anna, Altavista, Maria Concetta, Moschella, Vincenzo, Erro, Roberto, Barone, Paolo, Barbero, Pierangelo, Ceravolo, Roberto, Mazzucchi, Sonia, Mascia, Marcello Mario, Ercoli, Tommaso, Muroni, Antonella, Zibetti, Maurizio, Lopiano, Leonardo, Scaglione, Cesa Lorella Maria, Bentivoglio, Anna Rita, Petracca, Martina, Magistrelli, Luca, Cotelli, Maria Sofia, Cossu, Giovanni, Squintani, Giovanna Maddalena, De Santis, Tiziana, Schirinzi, Tommaso, Misceo, Salvatore, Pisani, Antonio, Berardelli, Alfredo, and Defazio, Giovanni

Published
2024
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2. Multidisciplinary care use in neurodegenerative complex diseases: The example of progressive supranuclear palsy and advanced Parkinson's disease in real-life

Author

Serio, Marina, Zibetti, Maurizio, Bissacco, Jacopo, Satolli, Sara, Sambati, Luisa, Bacchin, Ruggero, Longo, Chiara, Marchese, Roberta, Panetta, Salvatore, Magistrelli, Luca, Contaldi, Elena, Moschella, Vincenzo, Altavista, Maria Concetta, Costanzo, Matteo, Fabbrini, Giovanni, Olivola, Enrica, Modugno, Nicola, Cincotta, Massimo, Piccininni, Maristella, Capecci, Marianna, Baldini, Nicolò, Ciammola, Andrea, Ticozzi, Nicola, Raffaella, Di Giacopo, De Togni, Laura, Sala, Francesca, Nicoletti, Alessandra, Cicero, Edoardo, Ceravolo, Roberto, Del Prete, Eleonora, Fabbri, Margherita, Ledda, Claudia, Schirinzi, Tommaso, Artusi, Carlo Alberto, Avallone, Anna Rosa, Zenuni, Henri, De Micco, Rosa, Aloisio, Simone, Cani, Ilaria, Malaguti, Maria Chiara, Di Biasio, Francesca, Calandra-Buonaura, Giovanna, Stefani, Alessandro, Lopiano, Leonardo, Barone, Paolo, and Picillo, Marina

Published
2024
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3. The Italian tremor Network (TITAN): rationale, design and preliminary findings

Author

Erro, Roberto, Pilotto, Andrea, Esposito, Marcello, Olivola, Enrica, Nicoletti, Alessandra, Lazzeri, Giulia, Magistrelli, Luca, Dallocchio, Carlo, Marchese, Roberta, Bologna, Matteo, Tessitore, Alessandro, Misceo, Salvatore, Gigante, Angelo Fabio, Terranova, Carmen, Moschella, Vincenzo, di Biase, Lazzaro, Di Giacopo, Raffaella, Morgante, Francesca, Valentino, Francesca, De Rosa, Anna, Trinchillo, Assunta, Malaguti, Maria Chiara, Brusa, Livia, Matinella, Angela, Di Biasio, Francesca, Paparella, Giulia, De Micco, Rosa, Contaldi, Elena, Modugno, Nicola, Di Fonzo, Alessio, Padovani, Alessandro, and Barone, Paolo

Published
2022
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4. Spread of segmental/multifocal idiopathic adult-onset dystonia to a third body site

Author

Cimino, Paola, Scannapieco, Sara, Ferrazzano, Gina, Brigandì, Amelia, Habetswallner, Francesco, Pascarella, Angelo, Ialongo, Tamara, Ramella, Marina, Mazzucchi, Sonia, Moschella, Vincenzo, Ercoli, Tommaso, Erro, Roberto, Fabbrini, Giovanni, Pellicciari, Roberta, Girlanda, Paolo, Terranova, Carmen, Avanzino, Laura, Di Biasio, Francesca, Barone, Paolo, Esposito, Marcello, De Joanna, Gabriella, Eleopra, Roberto, Bono, Francesco, Manzo, Lucia, Bentivoglio, Anna Rita, Petracca, Martina, Mascia, Marcello Mario, Albanese, Alberto, Castagna, Anna, Ceravolo, Roberto, Altavista, Maria Concetta, Scaglione, Cesa, Magistrelli, Luca, Zibetti, Maurizio, Bertolasi, Laura, Coletti Moja, Mario, Cotelli, Maria Sofia, Cossu, Giovanni, Minafra, Brigida, Pisani, Antonio, Misceo, Salvatore, Modugno, Nicola, Romano, Marcello, Cassano, Daniela, Berardelli, Alfredo, and Defazio, Giovanni

Published
2021
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5. Correction to: The Italian tremor Network (TITAN): rationale, design and preliminary findings

Author

Erro, Roberto, Pilotto, Andrea, Esposito, Marcello, Olivola, Enrica, Nicoletti, Alessandra, Lazzeri, Giulia, Magistrelli, Luca, Dallocchio, Carlo, Marchese, Roberta, Bologna, Matteo, Tessitore, Alessandro, Misceo, Salvatore, Gigante, Angelo Fabio, Terranova, Carmen, Moschella, Vincenzo, di Biase, Lazzaro, Di Giacopo, Raffaella, Morgante, Francesca, Valentino, Francesca, De Rosa, Anna, Trinchillo, Assunta, Malaguti, Maria Chiara, Brusa, Livia, Matinella, Angela, Di Biasio, Francesca, Paparella, Giulia, De Micco, Rosa, Contaldi, Elena, Modugno, Nicola, Di Fonzo, Alessio, Padovani, Alessandro, and Barone, Paolo

Published
2022
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6. Comparing Essential Tremor with and without Soft Dystonic Signs and Tremor Combined with Dystonia: The TITAN Study.

Author

Erro, Roberto, Lazzeri, Giulia, Terranova, Carmen, Paparella, Giulia, Gigante, Angelo Fabio, De Micco, Rosa, Magistrelli, Luca, Di Biasio, Francesca, Valentino, Francesca, Moschella, Vincenzo, Pilotto, Andrea, Esposito, Marcello, Olivola, Enrica, Malaguti, Maria Chiara, Ceravolo, Roberto, Dallocchio, Carlo, Spagnolo, Francesca, Nicoletti, Alessandra, De Rosa, Anna, and Di Giacopo, Raffaella

Subjects
ESSENTIAL tremor, TREMOR, DYSTONIA, SEX distribution, REGRESSION analysis, QUALITY of life
Abstract

Background: Tremor disorders remain as clinical diagnoses and the rate of misdiagnosis between the commonest non‐parkinsonian tremors is relatively high. Objectives: To compare the clinical features of Essential Tremor without other features (pure ET), ET plus soft dystonic signs (ET + DS), and tremor combined with dystonia (TwD). Methods: We compared the clinical features of patients with pure ET, ET + DS, and TwD enrolled in The ITAlian tremor Network (TITAN). Linear regression models were performed to determine factors associated with health status and quality of life. Results: Three‐hundred‐eighty‐three patients were included. Sex distribution was significantly different between the groups with males being more represented in pure ET and females in TwD. The initial site of tremor was different between the groups with about 40% of TwD having head tremor and ET + DS unilateral upper limb tremor at onset. This pattern mirrored the distribution of overt dystonia and soft dystonic signs at examination. Sensory trick, task‐specificity, and position‐dependence were more common, but not exclusive, to TwD. Pure ET patients showed the lowest degree of alcohol responsiveness and ET + DS the highest. Midline tremor was more commonly encountered and more severe in TwD than in the other groups. Regression analyses demonstrated that tremor severity, sex, age, and to a lesser degree the variable "group", independently predicted health status and quality of life, suggesting the existence of other determinants beyond tremor. Conclusions: Pure ET and TwD manifest with a phenotypic overlap, which calls for the identification of diagnostic biomarkers. ET + DS shared features with both syndromes, suggesting intra‐group heterogeneity. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Phenotypic Variability in Acquired and Idiopathic Dystonia

Author

Defazio, Giovanni, primary, Gigante, Angelo Fabio, additional, Erro, Roberto, additional, Belvisi, Daniele, additional, Esposito, Marcello, additional, Trinchillo, Assunta, additional, De Joanna, Gabriella, additional, Ceravolo, Roberto, additional, Mazzucchi, Sonia, additional, Unti, Elisa, additional, Barone, Paolo, additional, Scannapieco, Sara, additional, Cotelli, Maria Sofia, additional, Turla, Marinella, additional, Bianchi, Marta, additional, Bertolasi, Laura, additional, Pisani, Antonio, additional, Valentino, Francesca, additional, Altavista, Maria Concetta, additional, Moschella, Vincenzo, additional, Girlanda, Paolo, additional, Terranova, Carmen, additional, Bono, Francesco, additional, Spano, Giorgio, additional, Fabbrini, Giovanni, additional, Ferrazzano, Gina, additional, Albanese, Alberto, additional, Castagna, Anna, additional, Cassano, Daniela, additional, Coletti Moja, Mario, additional, Pellicciari, Roberta, additional, Bentivoglio, Anna Rita, additional, Eleopra, Roberto, additional, Cossu, Giovanni, additional, Ercoli, Tommaso, additional, Mascia, Marcello Mario, additional, Di Biasio, Francesca, additional, Misceo, Salvatore, additional, Magistrelli, Luca, additional, Romano, Marcello, additional, Scaglione, Cesa Lorella Maria, additional, Tinazzi, Michele, additional, Maderna, Luca, additional, Zibetti, Maurizio, additional, and Berardelli, Alfredo, additional

Published
2023
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8. Phenotypic Variability in Acquired and Idiopathic Dystonia

Author

Defazio, Giovanni, Gigante, Angelo Fabio, Erro, Roberto, Belvisi, Daniele, Esposito, Marcello, Trinchillo, Assunta, De Joanna, Gabriella, Ceravolo, Roberto, Mazzucchi, Sonia, Unti, Elisa, Barone, Paolo, Scannapieco, Sara, Cotelli, Maria Sofia, Turla, Marinella, Bianchi, Marta, Bertolasi, Laura, Pisani, Antonio, Valentino, Francesca, Altavista, Maria Concetta, Moschella, Vincenzo, Girlanda, Paolo, Terranova, Carmen, Bono, Francesco, Spano, Giorgio, Fabbrini, Giovanni, Ferrazzano, Gina, Albanese, Alberto, Castagna, Anna, Cassano, Daniela, Coletti Moja, Mario, Pellicciari, Roberta, Bentivoglio, Anna Rita, Eleopra, Roberto, Cossu, Giovanni, Ercoli, Tommaso, Mascia, Marcello Mario, Di Biasio, Francesca, Misceo, Salvatore, Magistrelli, Luca, Romano, Marcello, Scaglione, Cesa Lorella Maria, Tinazzi, Michele, Maderna, Luca, Zibetti, Maurizio, Berardelli, Alfredo, Albanese, Alberto (ORCID:0000-0002-5864-0006), Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X), Defazio, Giovanni, Gigante, Angelo Fabio, Erro, Roberto, Belvisi, Daniele, Esposito, Marcello, Trinchillo, Assunta, De Joanna, Gabriella, Ceravolo, Roberto, Mazzucchi, Sonia, Unti, Elisa, Barone, Paolo, Scannapieco, Sara, Cotelli, Maria Sofia, Turla, Marinella, Bianchi, Marta, Bertolasi, Laura, Pisani, Antonio, Valentino, Francesca, Altavista, Maria Concetta, Moschella, Vincenzo, Girlanda, Paolo, Terranova, Carmen, Bono, Francesco, Spano, Giorgio, Fabbrini, Giovanni, Ferrazzano, Gina, Albanese, Alberto, Castagna, Anna, Cassano, Daniela, Coletti Moja, Mario, Pellicciari, Roberta, Bentivoglio, Anna Rita, Eleopra, Roberto, Cossu, Giovanni, Ercoli, Tommaso, Mascia, Marcello Mario, Di Biasio, Francesca, Misceo, Salvatore, Magistrelli, Luca, Romano, Marcello, Scaglione, Cesa Lorella Maria, Tinazzi, Michele, Maderna, Luca, Zibetti, Maurizio, Berardelli, Alfredo, Albanese, Alberto (ORCID:0000-0002-5864-0006), and Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X)

Abstract

BackgroundTo date, a few studies have systematically investigated differences in the clinical spectrum between acquired and idiopathic dystonias. ObjectivesTo compare demographic data and clinical features in patients with adult-onset acquired and idiopathic dystonias. MethodsPatients were identified from among those included in the Italian Dystonia Registry, a multicenter Italian dataset of patients with adult-onset dystonia. Study population included 116 patients with adult-onset acquired dystonia and 651 patients with isolated adult-onset idiopathic dystonia. ResultsComparison of acquired and idiopathic dystonia revealed differences in the body distribution of dystonia, with oromandibular dystonia, limb and trunk dystonia being more frequent in patients with acquired dystonia. The acquired dystonia group was also characterized by lower age at dystonia onset, greater tendency to spread, lower frequency of head tremor, sensory trick and eye symptoms, and similar frequency of neck pain associated with CD and family history of dystonia/tremor. ConclusionsThe clinical phenomenology of dystonia may differ between acquired and idiopathic dystonia, particularly with regard to the body localization of dystonia and the tendency to spread. This dissimilarity raises the possibility of pathophysiological differences between etiologic categories.

Published
2023

10. Clinical correlates of "pure" essential tremor: the TITAN study.

Author

Erro, Roberto, Lazzeri, Giulia, Gigante, Angelo Fabio, Pilotto, Andrea, Magistrelli, Luca, Bologna, Matteo, Terranova, Carmen, Olivola, Enrica, Dallocchio, Carlo, Moschella, Vincenzo, Valentino, Francesca, Di Biasio, Francesca, Nicoletti, Alessandra, De Micco, Rosa, Brusa, Livia, Sorrentino, Cristiano, Matinella, Angela, Bertino, Salvatore, Paparella, Giulia, and Modugno, Nicola

Subjects
TREMOR, ESSENTIAL tremor, AGE of onset, DISEASE duration, AGE distribution, SEX distribution, DATABASES
Abstract

Background: To date, there are no large studies delineating the clinical correlates of "pure" essential tremor (ET) according to its new definition. Methods: From the ITAlian tremor Network (TITAN) database, we extracted data from patients with a diagnosis of "pure" ET and excluded those with other tremor classifications, including ET-plus, focal, and task-specific tremor, which were formerly considered parts of the ET spectrum. Results: Out of 653 subjects recruited in the TITAN study by January 2022, the data of 208 (31.8%) "pure" ET patients (86M/122F) were analyzed. The distribution of age at onset was found to be bimodal. The proportion of familial cases by the age-at-onset class of 20 years showed significant differences, with sporadic cases representing the large majority of the class with an age at onset above 60 years. Patients with a positive family history of tremor had a younger onset and were more likely to have leg involvement than sporadic patients despite a similar disease duration. Early-onset and late-onset cases were different in terms of tremor distribution at onset and tremor severity, likely as a function of longer disease duration, yet without differences in terms of quality of life, which suggests a relatively benign progression. Treatment patterns and outcomes revealed that up to 40% of the sample was unsatisfied with the current pharmacological options. Discussion: The findings reported in the study provide new insights, especially with regard to a possible inversed sex distribution, and to the genetic backgrounds of "pure" ET, given that familial cases were evenly distributed across age-at-onset classes of 20 years. Deep clinical profiling of "pure" ET, for instance, according to age at onset, might increase the clinical value of this syndrome in identifying pathogenetic hypotheses and therapeutic strategies. [ABSTRACT FROM AUTHOR]

Published
2023
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11. A Bayesian approach to Essential Tremor plus: A preliminary analysis of the TITAN cohort

Author

Angela Matinella, Sciarretta, Massimo, Perillo, Sandra, Giglio, Augusta, Raglione, Laura Maria, Terranova, Carmen, Altavista, Maria Concetta, Spagnolo, Francesca, Pecoraro, Pasquale Maria, Malaguti, Maria Chiara, Misceo, Salvatore, Zoccolella, Stefano, Marchese, Roberta, Benzi, Tiziana, Gallo, Silvia, Paparella, Giulia, Angelini, Luca, Lazzeri, Giulia, Franco, Giulia, Di Giacopo, Raffaella, De Micco, Rosa, Aramini, Simone, Ceravolo, Roberto, Mostile, Giovanni, Morgante, Francesca, Brusa, Livia, Erro, Roberto, Pilotto, Andrea, Magistrelli, Luca, Olivola, Enrica, Nicoletti, Alessandra, Di Fonzo, Alessio, Dallocchio, Carlo, Di Biasio, Francesca, Bologna, Matteo, Tessitore, Alessandro, De Rosa, Anna, Gigante, Angelo Fabio, Esposito, Marcello, Moschella, Vincenzo, di Biase, Lazzaro, Valentino, Francesca, Russo, Maria, Contaldi, Elena, Modugno, Nicola, Padovani, Alessandro, and Barone, Paolo

Published
2022
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13. Spread of segmental/multifocal idiopathic adult-onset dystonia to a third body site

Author

Ercoli, Tommaso, primary, Erro, Roberto, additional, Fabbrini, Giovanni, additional, Pellicciari, Roberta, additional, Girlanda, Paolo, additional, Terranova, Carmen, additional, Avanzino, Laura, additional, Di Biasio, Francesca, additional, Barone, Paolo, additional, Esposito, Marcello, additional, De Joanna, Gabriella, additional, Eleopra, Roberto, additional, Bono, Francesco, additional, Manzo, Lucia, additional, Bentivoglio, Anna Rita, additional, Petracca, Martina, additional, Mascia, Marcello Mario, additional, Albanese, Alberto, additional, Castagna, Anna, additional, Ceravolo, Roberto, additional, Altavista, Maria Concetta, additional, Scaglione, Cesa, additional, Magistrelli, Luca, additional, Zibetti, Maurizio, additional, Bertolasi, Laura, additional, Coletti Moja, Mario, additional, Cotelli, Maria Sofia, additional, Cossu, Giovanni, additional, Minafra, Brigida, additional, Pisani, Antonio, additional, Misceo, Salvatore, additional, Modugno, Nicola, additional, Romano, Marcello, additional, Cassano, Daniela, additional, Berardelli, Alfredo, additional, Defazio, Giovanni, additional, Cimino, Paola, additional, Scannapieco, Sara, additional, Ferrazzano, Gina, additional, Brigandì, Amelia, additional, Habetswallner, Francesco, additional, Pascarella, Angelo, additional, Ialongo, Tamara, additional, Ramella, Marina, additional, Mazzucchi, Sonia, additional, and Moschella, Vincenzo, additional

Published
2021
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15. Motor and Sensory Features of Cervical Dystonia Subtypes: Data From the Italian Dystonia Registry

Author

Di Biasio, Francesca, primary, Marchese, Roberta, additional, Abbruzzese, Giovanni, additional, Baldi, Ottavia, additional, Esposito, Marcello, additional, Silvestre, Francesco, additional, Tescione, Girolamo, additional, Berardelli, Alfredo, additional, Fabbrini, Giovanni, additional, Ferrazzano, Gina, additional, Pellicciari, Roberta, additional, Eleopra, Roberto, additional, Devigili, Grazia, additional, Bono, Francesco, additional, Santangelo, Domenico, additional, Bertolasi, Laura, additional, Altavista, Maria Concetta, additional, Moschella, Vincenzo, additional, Barone, Paolo, additional, Erro, Roberto, additional, Albanese, Alberto, additional, Scaglione, Cesa, additional, Liguori, Rocco, additional, Cotelli, Maria Sofia, additional, Cossu, Giovanni, additional, Ceravolo, Roberto, additional, Coletti Moja, Mario, additional, Zibetti, Maurizio, additional, Pisani, Antonio, additional, Petracca, Martina, additional, Tinazzi, Michele, additional, Maderna, Luca, additional, Girlanda, Paolo, additional, Magistrelli, Luca, additional, Misceo, Salvatore, additional, Romano, Marcello, additional, Minafra, Brigida, additional, Modugno, Nicola, additional, Aguggia, Marco, additional, Cassano, Daniela, additional, Defazio, Giovanni, additional, and Avanzino, Laura, additional

Published
2020
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26. A Bayesian approach to Essential Tremor plus: A preliminary analysis of the TITAN cohort.

Author

Erro, Roberto, Pilotto, Andrea, Magistrelli, Luca, Olivola, Enrica, Nicoletti, Alessandra, Di Fonzo, Alessio, Dallocchio, Carlo, Di Biasio, Francesca, Bologna, Matteo, Tessitore, Alessandro, De Rosa, Anna, Gigante, Angelo Fabio, Esposito, Marcello, Moschella, Vincenzo, di Biase, Lazzaro, Valentino, Francesca, Russo, Maria, Contaldi, Elena, Modugno, Nicola, and Padovani, Alessandro

Subjects
*DYSTONIA, *TREMOR, *ESSENTIAL tremor, *PROBABILITY theory, *LONGITUDINAL method
Abstract

Background: The construct of Essential Tremor plus (ET-plus) refers to patients who also have rest tremor and/or mild neurologic signs of unknown significance. It is unclear whether soft signs represent confounding factors or are useful in suspecting an alternative condition.Methods: Using a Bayesian approach to ET-plus patients recruited in The ITAlian tremor Network (TITAN), we analyzed the probability that these patients do not have ET.Results: The data of 274 ET-plus patients were extracted from the TITAN database. The majority of patients (240/274; 87.5%) had a single soft sign. The post-test probability of not having ET was different according to the specific soft sign: namely, 0.64 (rest tremor); 0.46 (questionable dystonia); 0.85 (questionable bradykinesia); 0.19 (soft gait impairment); and 0.09 (questionable cognitive issues). In patients with multiple soft signs, the post-test probability of not having ET was higher than 50% for 7 out of 11 combinations, accounting for 44.1% of subjects. Overall, the post-test probability of not having ET was higher than 50% in up to 71.5% of ET-plus patients.Discussion: We have here shown that: 1) the soft signs differently contribute in modulating the probability that a patient does not have ET; and 2) the effect of multiple soft signs are not always addictive. Future studies are needed to collect prevalence figures of soft signs in different neurological disorders as well as in the elderly and to calculate their value in predicting the development of an alternative tremor syndrome. [ABSTRACT FROM AUTHOR]

Published
2022
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