641 results on '"Moscat, Jorge"'
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2. Sessile serrated lesions with dysplasia: is it possible to nip them in the bud?
3. Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis
4. THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer
5. S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia.
6. NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ.
7. Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
8. Fructose stimulated de novo lipogenesis is promoted by inflammation
9. PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
10. NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly
11. Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
12. miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
13. p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
14. p62 in Cancer: Signaling Adaptor Beyond Autophagy
15. Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι
16. p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells
17. NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
18. Serrated Colorectal Cancer: The Road Less Travelled?
19. Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis.
20. Metabolic reprogramming of the tumor microenvironment by p62 and its partners
21. ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma
22. Control of T Helper 2 Cell Function and Allergic Airway Inflammation by PKCζ
23. Regulation of Heterogenous Nuclear Ribonucleoprotein A1 Transport by Phosphorylation in Cells Stressed by Osmotic Shock
24. The Death Receptor Antagonist FAIM Promotes Neurite Outgrowth by a Mechanism That Depends on ERK and NF-κB Signaling
25. DaPKC-Dependent Phosphorylation of Crumbs Is Required for Epithelial Cell Polarity in Drosophila
26. Whole-mount staining of mouse colorectal cancer organoids and fibroblast-organoid co-cultures
27. The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation
28. The MKK 3/6 - p38-Signaling Cascade Alters the Subcellular Distribution of hnRNP A1 and Modulates Alternative Splicing Regulation
29. Supplementary Table S1 from p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis
30. Raw data for Supplementary Table 1 and 2 from p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis
31. Figure S4 from p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis
32. Supplementary Materials and Methods from p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis
33. Data from p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis
34. Supplementary Figure Legends from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
35. Supplementary Tables 1-3 from Inactivation of the Candidate Tumor Suppressor Par-4 in Endometrial Cancer
36. Supplementary Figure S6 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
37. Data from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
38. Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer
39. Protein kinase Cλ/ι in cancer: a contextual balance of time and signals
40. Air-liquid organotypic assays to investigate cellular crosstalk in the tumor microenvironment of cancer cells
41. Atypical PKCs, NF-κB, and Inflammation
42. A Macrophage NBR1-MEKK3 Complex Triggers JNK-Mediated Adipose Tissue Inflammation in Obesity
43. Protocol to characterize mouse intestinal epithelial cell lineage using Opal multiplex immunofluorescence
44. ZZ-dependent regulation of p62/SQSTM1 in autophagy
45. The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
46. c-Myc phosphorylation by PKCζ represses prostate tumorigenesis
47. TRAF6 and p62 inhibit amyloid β-induced neuronal death through p75 neurotrophin receptor
48. Atypical protein kinase C (aPKCζ and aPKCλ) is dispensable for mammalian hematopoietic stem cell activity and blood formation
49. Simultaneous Inactivation of Par-4 and PTEN in vivo Leads to Synergistic NF-κB Activation and Invasive Prostate Carcinoma
50. Loss of PKCλ/ι Impairs Th2 Establishment and Allergic Airway Inflammation in Vivo
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