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1,468 results on '"Morrison, Alanna C."'

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1. Rare variant contribution to the heritability of coronary artery disease

2. Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores

4. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

6. Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits.

7. Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations

8. Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.

9. Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification

10. Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies

11. Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer’s disease at CPT1A locus

12. Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups

13. Coronary heart disease and ischemic stroke polygenic risk scores and atherosclerotic cardiovascular disease in a diverse, population-based cohort study.

14. Correlations between complex human phenotypes vary by genetic background, gender, and environment

15. A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

16. Rare coding variants in RCN3 are associated with blood pressure

17. Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data

18. Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

20. Understanding the complex genetic architecture connecting rheumatoid arthritis, osteoporosis and inflammation: discovering causal pathways

21. Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

22. Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure

24. Genetic insights into resting heart rate and its role in cardiovascular disease

25. Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program

26. Monogenic and Polygenic Contributions to QTc Prolongation in the Population.

27. Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential

28. Clonal Hematopoiesis Is Associated With Higher Risk of Stroke

29. Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts

30. A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

31. A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment

32. Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative

33. Whole genome sequence analysis of blood lipid levels in >66,000 individuals

34. Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

35. Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations

36. Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program

37. A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood

38. Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program

39. A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program

40. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

42. Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

43. FGL1 as a modulator of plasma D‐dimer levels: Exome‐wide marker analysis of plasma tPA, PAI‐1, and D‐dimer

44. BinomiRare: A robust test for association of a rare genetic variant with a binary outcome for mixed models and any case-control proportion

45. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.

46. Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program

47. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.

49. Genetic diversity fuels gene discovery for tobacco and alcohol use

50. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

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