203 results on '"Moris L"'
Search Results
2. The role of artificial intelligence in urological cancers: An overview of systematic reviews
- Author
-
Sakalis, V., primary, Pang, K., additional, Rai, B., additional, Moris, L., additional, Yuan, Y., additional, N’dow, J., additional, and Omar, M.I., additional
- Published
- 2024
- Full Text
- View/download PDF
3. How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis
- Author
-
N’Dow, J., Smith, E.J., Shepherd, R., Ribal, M., Mottet, N., Moris, L., Lardas, M., Willemse, P-P., Gandaglia, G., Campi, R., Nicoletti, Rossella, Gacci, M., Briganti, A., Ratti, M.M., Alleva, E., Leardini, L., Sisca, E.S., Bangma, R., Roobol, M., Remmers, S., Tilki, D., Visakorpi, T., Talala, K., Tammela, T., van Hemelrijck, M., Bayer, K., Lejeune, S., Byrne, S., Fialho, L., De Meulder, P. Palaiologou B., Auffray, C., Hijazy, A., Power, S., Kermani, N. Zounemat, van Bochove, K., Kalafati, M., Moinat, M., Voss, E., Horgan, D., Fullwood, L., Holtorf, M., Lancet, D., Bernstein, G., Omar, I., MacLennan, S., Maclennan, S., Tripathee, S., Wirth, M., Froehner, M., Brenner, B., Borkowetz, A., Thomas, C., Horn, F., Reiche, K., Kreux, M., Josefsson, A., Tandefekt, D. Gasi, Hugosson, J., Huisman, H., Schalken, J., Hofmacher, T., Lindgren, P., Andersson, E., Fridhammar, A., Zong, J., Butler-Ransohoff, J-E., Herrera, R., Maass, M., Torremante, P., Voss, M.D., Devecseri, Z., Abbott, T., Dau, C., Papineni, K., Snijder, R., Lambrecht, M., Wolfinger, R., Rogiers, S., Servan, A., Antoni, L., Pacoe, K., Robinson, P., Jaton, B., Bakkard, D., Turunen, H., Kilkku, O., Pohjanjousi, P., Voima, O., Nevalaita, L., Reich, C., Araujo, S., Longden-Chapman, E., Burke, D., Agapow, P., Derkits, S., Licour, M., McCrea, C., Payne, S., Yong, A., Thompson, L., Mare, S. Le, Bussmann, M, Kotik, D., Siltari, Aino, Lönnerbro, Ragnar, Pang, Karl, Shiranov, Kirill, Asiimwe, Alex, Evans-Axelsson, Susan, Franks, Billy, Kiran, Amit, Murtola, Teemu J., Schalken, Jack, Steinbeisser, Carl, Bjartell, Anders, and Auvinen, Anssi
- Published
- 2023
- Full Text
- View/download PDF
4. How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis
- Author
-
Siltari, Aino, primary, Lönnerbro, Ragnar, additional, Pang, Karl, additional, Shiranov, Kirill, additional, Asiimwe, Alex, additional, Evans-Axelsson, Susan, additional, Franks, Billy, additional, Kiran, Amit, additional, Murtola, Teemu J., additional, Schalken, Jack, additional, Steinbeisser, Carl, additional, Bjartell, Anders, additional, Auvinen, Anssi, additional, N’Dow, J., additional, Smith, E.J., additional, Shepherd, R., additional, Ribal, M., additional, Mottet, N., additional, Moris, L., additional, Lardas, M., additional, Willemse, P-P., additional, Gandaglia, G., additional, Campi, R., additional, Nicoletti, Rossella, additional, Gacci, M., additional, Briganti, A., additional, Ratti, M.M., additional, Alleva, E., additional, Leardini, L., additional, Sisca, E.S., additional, Bangma, R., additional, Roobol, M., additional, Remmers, S., additional, Tilki, D., additional, Visakorpi, T., additional, Talala, K., additional, Tammela, T., additional, van Hemelrijck, M., additional, Bayer, K., additional, Lejeune, S., additional, Byrne, S., additional, Fialho, L., additional, De Meulder, P. Palaiologou B., additional, Auffray, C., additional, Hijazy, A., additional, Power, S., additional, Kermani, N. Zounemat, additional, van Bochove, K., additional, Kalafati, M., additional, Moinat, M., additional, Voss, E., additional, Horgan, D., additional, Fullwood, L., additional, Holtorf, M., additional, Lancet, D., additional, Bernstein, G., additional, Omar, I., additional, MacLennan, S., additional, Maclennan, S., additional, Tripathee, S., additional, Wirth, M., additional, Froehner, M., additional, Brenner, B., additional, Borkowetz, A., additional, Thomas, C., additional, Horn, F., additional, Reiche, K., additional, Kreux, M., additional, Josefsson, A., additional, Tandefekt, D. Gasi, additional, Hugosson, J., additional, Huisman, H., additional, Schalken, J., additional, Hofmacher, T., additional, Lindgren, P., additional, Andersson, E., additional, Fridhammar, A., additional, Zong, J., additional, Butler-Ransohoff, J-E., additional, Herrera, R., additional, Maass, M., additional, Torremante, P., additional, Voss, M.D., additional, Devecseri, Z., additional, Abbott, T., additional, Dau, C., additional, Papineni, K., additional, Snijder, R., additional, Lambrecht, M., additional, Wolfinger, R., additional, Rogiers, S., additional, Servan, A., additional, Antoni, L., additional, Pacoe, K., additional, Robinson, P., additional, Jaton, B., additional, Bakkard, D., additional, Turunen, H., additional, Kilkku, O., additional, Pohjanjousi, P., additional, Voima, O., additional, Nevalaita, L., additional, Reich, C., additional, Araujo, S., additional, Longden-Chapman, E., additional, Burke, D., additional, Agapow, P., additional, Derkits, S., additional, Licour, M., additional, McCrea, C., additional, Payne, S., additional, Yong, A., additional, Thompson, L., additional, Mare, S. Le, additional, Bussmann, M, additional, and Kotik, D., additional
- Published
- 2023
- Full Text
- View/download PDF
5. The survival impact of neoadjuvant hormonal therapy before radical prostatectomy for treatment of high-risk prostate cancer
- Author
-
Tosco, L, Laenen, A, Briganti, A, Gontero, P, Karnes, R J, Albersen, M, Bastian, P J, Chlosta, P, Claessens, F, Chun, F K, Everaerts, W, Gratzke, C, Graefen, M, Kneitz, B, Marchioro, G, Salas, R S, Tombal, B, Van den Broeck, T, Moris, L, Battaglia, A, van der Poel, H, Walz, J, Bossi, A, De Meerleer, G, Haustermans, K, Van Poppel, H, Spahn, M, and Joniau, S
- Published
- 2017
- Full Text
- View/download PDF
6. Updating and Integrating Core Outcome Sets for Localised, Locally Advanced, Metastatic, and Nonmetastatic Castration-resistant Prostate Cancer: An Update from the PIONEER Consortium
- Author
-
Beyer, K., Moris, L., Lardas, M., Omar, M.I., Healey, J., Tripathee, S., Gandaglia, G., Venderbos, L.D.F., Vradi, E., Broeck, T. Van den, Willemse, P.P., Antunes-Lopes, T., Pacheco-Figueiredo, L., Monagas, S., Esperto, F., Flaherty, S., Devecseri, Z., Lam, T.B., Williamson, P.R., Heer, R., Smith, E.J., Asiimwe, A., Huber, J., Roobol, M.J., Zong, J., Mason, M., Cornford, P., Mottet, N., MacLennan, S.J., N'Dow, J., Briganti, A., Huisman, H.J., MacLennan, S., Hemelrijck, M. Van, and Urology
- Subjects
Male ,Prostatic Neoplasms, Castration-Resistant ,Consensus ,SDG 3 - Good Health and Well-being ,Urology ,Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] ,Outcome Assessment, Health Care ,Humans ,Orchiectomy - Abstract
Contains fulltext : 288445.pdf (Publisher’s version ) (Open Access) CONTEXT: Harmonisation of outcome reporting and definitions for clinical trials and routine patient records can enable health care systems to provide more efficient outcome-driven and patient-centred interventions. We report on the work of the PIONEER Consortium in this context for prostate cancer (PCa). OBJECTIVE: To update and integrate existing core outcome sets (COS) for PCa for the different stages of the disease, assess their applicability, and develop standardised definitions of prioritised outcomes. EVIDENCE ACQUISITION: We followed a four-stage process involving: (1) systematic reviews; (2) qualitative interviews; (3) expert group meetings to agree standardised terminologies; and (4) recommendations for the most appropriate definitions of clinician-reported outcomes. EVIDENCE SYNTHESIS: Following four systematic reviews, a multinational interview study, and expert group consensus meetings, we defined the most clinically suitable definitions for (1) COS for localised and locally advanced PCa and (2) COS for metastatic and nonmetastatic castration-resistant PCa. No new outcomes were identified in our COS for localised and locally advanced PCa. For our COS for metastatic and nonmetastatic castration-resistant PCa, nine new core outcomes were identified. CONCLUSIONS: These are the first COS for PCa for which the definitions of prioritised outcomes have been surveyed in a systematic, transparent, and replicable way. This is also the first time that outcome definitions across all prostate cancer COS have been agreed on by a multidisciplinary expert group and recommended for use in research and clinical practice. To limit heterogeneity across research, these COS should be recommended for future effectiveness trials, systematic reviews, guidelines and clinical practice of localised and metastatic PCa. PATIENT SUMMARY: Patient outcomes after treatment for prostate cancer (PCa) are difficult to compare because of variability. To allow better use of data from patients with PCa, the PIONEER Consortium has standardised and recommended outcomes (and their definitions) that should be collected as a minimum in all future studies.
- Published
- 2022
7. Diagnostic and prognostic factors in patients with prostate cancer: a systematic review
- Author
-
Beyer, K., Moris, L., Lardas, M., Haire, A., Barletta, F., Scuderi, S., Molnar, M., Herrera, R., Rauf, A., Campi, R., Greco, I., Shiranov, K., Dabestani, S., Broeck, T. Van den, Arun, S., Gacci, M., Gandaglia, G., Omar, M.I., MacLennan, S., Roobol, M.J., Farahmand, B., Vradi, E., Devecseri, Z., Asiimwe, A., Zong, J., MacLennan, S.J., Collette, L., J, N.D., Briganti, A., Huisman, H.J., Bjartell, A., Hemelrijck, M. Van, Beyer, K., Moris, L., Lardas, M., Haire, A., Barletta, F., Scuderi, S., Molnar, M., Herrera, R., Rauf, A., Campi, R., Greco, I., Shiranov, K., Dabestani, S., Broeck, T. Van den, Arun, S., Gacci, M., Gandaglia, G., Omar, M.I., MacLennan, S., Roobol, M.J., Farahmand, B., Vradi, E., Devecseri, Z., Asiimwe, A., Zong, J., MacLennan, S.J., Collette, L., J, N.D., Briganti, A., Huisman, H.J., Bjartell, A., and Hemelrijck, M. Van
- Abstract
Item does not contain fulltext, OBJECTIVES: As part of the PIONEER Consortium objectives, we have explored which diagnostic and prognostic factors (DPFs) are available in relation to our previously defined clinician and patient-reported outcomes for prostate cancer (PCa). DESIGN: We performed a systematic review to identify validated and non-validated studies. DATA SOURCES: MEDLINE, Embase and the Cochrane Library were searched on 21 January 2020. ELIGIBILITY CRITERIA: Only quantitative studies were included. Single studies with fewer than 50 participants, published before 2014 and looking at outcomes which are not prioritised in the PIONEER core outcome set were excluded. DATA EXTRACTION AND SYNTHESIS: After initial screening, we extracted data following the Checklist for Critical Appraisal and Data Extraction for Systematic Reviews of prognostic factor studies (CHARMS-PF) criteria and discussed the identified factors with a multidisciplinary expert group. The quality of the included papers was scored for applicability and risk of bias using validated tools such as PROBAST, Quality in Prognostic Studies and Quality Assessment of Diagnostic Accuracy Studies 2. RESULTS: The search identified 6604 studies, from which 489 DPFs were included. Sixty-four of those were internally or externally validated. However, only three studies on diagnostic and seven studies on prognostic factors had a low risk of bias and a low risk concerning applicability. CONCLUSION: Most of the DPFs identified require additional evaluation and validation in properly designed studies before they can be recommended for use in clinical practice. The PIONEER online search tool for DPFs for PCa will enable researchers to understand the quality of the current research and help them design future studies. ETHICS AND DISSEMINATION: There are no ethical implications.
- Published
- 2022
8. Introducing PIONEER: a project to harness big data in prostate cancer research
- Author
-
Omar M. I., Roobol M. J., Ribal M. J., Abbott T., Agapow P. -M., Araujo S., Asiimwe A., Auffray C., Balaur I., Beyer K., Bernini C., Bjartell A., Briganti A., Butler-Ransohoff J. -E., Campi R., Cavelaars M., De Meulder B., Devecseri Z., Voss M. D., Dimitropoulos K., Evans-Axelsson S., Franks B., Fullwood L., Horgan D., Smith E. J., Kiran A., Kivinummi K., Lambrecht M., Lancet D., Lindgren P., MacLennan S., Nogueira M. M., Moen F., Moinat M., Papineni K., Reich C., Reiche K., Rogiers S., Sartini C., van Bochove K., van Diggelen F., Van Hemelrijck M., Van Poppel H., Zong J., N'Dow J., Andersson E., Arala H., Auvinen A., Bangma C., Burke D., Cardone A., Casariego J., Cuperus G., Dabestani S., Esperto F., Fossati N., Fridhammar A., Gandaglia G., Tandefelt D. G., Horn F., Huber J., Hugosson J., Huisman H., Josefsson A., Kilkku O., Kreuz M., Lardas M., Lawson J., Lefresne F., Lejeune S., Longden-Chapman E., McVie G., Moris L., Mottet N., Murtola T., Nicholls C., Pang K. H., Pascoe K., Picozzi M., Plass K., Pohjanjousi P., Reaney M., Remmers S., Robinson P., Schalken J., Schravendeel M., Seisen T., Servan A., Shiranov K., Snijder R., Steinbeisser C., Taibi N., Talala K., Tilki D., Van den Broeck T., Vassilev Z., Voima O., Vradi E., Waldeck R., Weistra W., Willemse P. -P., Wirth M., Wolfinger R., Kermani N. Z., Omar, M. I., Roobol, M. J., Ribal, M. J., Abbott, T., Agapow, P. -M., Araujo, S., Asiimwe, A., Auffray, C., Balaur, I., Beyer, K., Bernini, C., Bjartell, A., Briganti, A., Butler-Ransohoff, J. -E., Campi, R., Cavelaars, M., De Meulder, B., Devecseri, Z., Voss, M. D., Dimitropoulos, K., Evans-Axelsson, S., Franks, B., Fullwood, L., Horgan, D., Smith, E. J., Kiran, A., Kivinummi, K., Lambrecht, M., Lancet, D., Lindgren, P., Maclennan, S., Nogueira, M. M., Moen, F., Moinat, M., Papineni, K., Reich, C., Reiche, K., Rogiers, S., Sartini, C., van Bochove, K., van Diggelen, F., Van Hemelrijck, M., Van Poppel, H., Zong, J., N'Dow, J., Andersson, E., Arala, H., Auvinen, A., Bangma, C., Burke, D., Cardone, A., Casariego, J., Cuperus, G., Dabestani, S., Esperto, F., Fossati, N., Fridhammar, A., Gandaglia, G., Tandefelt, D. G., Horn, F., Huber, J., Hugosson, J., Huisman, H., Josefsson, A., Kilkku, O., Kreuz, M., Lardas, M., Lawson, J., Lefresne, F., Lejeune, S., Longden-Chapman, E., Mcvie, G., Moris, L., Mottet, N., Murtola, T., Nicholls, C., Pang, K. H., Pascoe, K., Picozzi, M., Plass, K., Pohjanjousi, P., Reaney, M., Remmers, S., Robinson, P., Schalken, J., Schravendeel, M., Seisen, T., Servan, A., Shiranov, K., Snijder, R., Steinbeisser, C., Taibi, N., Talala, K., Tilki, D., Van den Broeck, T., Vassilev, Z., Voima, O., Vradi, E., Waldeck, R., Weistra, W., Willemse, P. -P., Wirth, M., Wolfinger, R., Kermani, N. Z., Publica, and Urology
- Subjects
0301 basic medicine ,Prioritization ,Knowledge management ,Urology ,media_common.quotation_subject ,education ,Big data ,Disease ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,SDG 3 - Good Health and Well-being ,Multidisciplinary approach ,Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15] ,Medicine ,Quality (business) ,media_common ,business.industry ,Patient-centered outcomes ,medicine.disease ,3. Good health ,Patient management ,030104 developmental biology ,Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] ,030220 oncology & carcinogenesis ,business - Abstract
Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is to provide high-quality evidence on prostate cancer management by unlocking the potential of big data. The project has identified critical evidence gaps in prostate cancer care, via a detailed prioritization exercise including all key stakeholders. By standardizing and integrating existing high-quality and multidisciplinary data sources from patients with prostate cancer across different stages of the disease, the resulting big data will be assembled into a single innovative data platform for research. Based on a unique set of methodologies, PIONEER aims to advance the field of prostate cancer care with a particular focus on improving prostate-cancer-related outcomes, health system efficiency by streamlining patient management, and the quality of health and social care delivered to all men with prostate cancer and their families worldwide.Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. In this Perspectives article, the authors introduce the PIONEER project and describe its aims and plans for ultimately improving prostate cancer care through the use of big data.
- Published
- 2020
9. Re: Andrew Vickers, Sigrid V. Carlsson, Matthew Cooperberg. Routine Use of Magnetic Resonance Imaging for Early Detection of Prostate Cancer Is Not Justified by the Clinical Trial Evidence. Eur Urol 2020;78:304–6: Prebiopsy MRI: Through the Looking Glass
- Author
-
van den Bergh R. C. N., Rouviere O., van der Kwast T., Briers E., Van den Broeck T., Cornford P., Cumberbatch M. G., De Santis M., Fanti S., Fossati N., Gandaglia G., Grivas N., Grummet J., Lam T. B., Lardas M., Liew M., Moris L., Mason M. D., Mottet N., Oprea-Lager D. E., Ploussard G., Schoots I. G., Tilki D., van der Poel H. G., Wiegel T., Willemse P. -P. M., van den Bergh, R. C. N., Rouviere, O., van der Kwast, T., Briers, E., Van den Broeck, T., Cornford, P., Cumberbatch, M. G., De Santis, M., Fanti, S., Fossati, N., Gandaglia, G., Grivas, N., Grummet, J., Lam, T. B., Lardas, M., Liew, M., Moris, L., Mason, M. D., Mottet, N., Oprea-Lager, D. E., Ploussard, G., Schoots, I. G., Tilki, D., van der Poel, H. G., Wiegel, T., and Willemse, P. -P. M.
- Subjects
Male ,Humans ,Prostatic Neoplasms ,Magnetic Resonance Imaging - Published
- 2020
10. Author Correction: Introducing PIONEER: a project to harness big data in prostate cancer research (Nature Reviews Urology, (2020), 17, 6, (351-362), 10.1038/s41585-020-0324-x)
- Author
-
Omar M. I., Roobol M. J., Ribal M. J., Abbott T., Agapow P. -M., Araujo S., Asiimwe A., Auffray C., Balaur I., Beyer K., Bernini C., Bjartell A., Briganti A., Butler-Ransohoff J. -E., Campi R., Cavelaars M., De Meulder B., Devecseri Z., Voss M. D., Dimitropoulos K., Evans-Axelsson S., Franks B., Fullwood L., Horgan D., Smith E. J., Kiran A., Kivinummi K., Lambrecht M., Lancet D., Lindgren P., MacLennan S., Nogueira M. M., Moen F., Moinat M., Papineni K., Reich C., Reiche K., Rogiers S., Sartini C., van Bochove K., van Diggelen F., Van Hemelrijck M., Van Poppel H., Zong J., N'Dow J., Andersson E., Arala H., Auvinen A., Bangma C., Burke D., Cardone A., Casariego J., Cuperus G., Dabestani S., Esperto F., Fossati N., Fridhammar A., Gandaglia G., Tandefelt D. G., Horn F., Huber J., Hugosson J., Huisman H., Josefsson A., Kilkku O., Kreuz M., Lardas M., Lawson J., Lefresne F., Lejeune S., Longden-Chapman E., McVie G., Moris L., Mottet N., Murtola T., Nicholls C., Pang K. H., Pascoe K., Picozzi M., Plass K., Pohjanjousi P., Reaney M., Remmers S., Robinson P., Schalken J., Schravendeel M., Seisen T., Servan A., Shiranov K., Snijder R., Steinbeisser C., Taibi N., Talala K., Tilki D., Van den Broeck T., Vassilev Z., Voima O., Vradi E., Waldeck R., Weistra W., Willemse P. -P., Wirth M., Wolfinger R., Kermani N. Z., Omar, M. I., Roobol, M. J., Ribal, M. J., Abbott, T., Agapow, P. -M., Araujo, S., Asiimwe, A., Auffray, C., Balaur, I., Beyer, K., Bernini, C., Bjartell, A., Briganti, A., Butler-Ransohoff, J. -E., Campi, R., Cavelaars, M., De Meulder, B., Devecseri, Z., Voss, M. D., Dimitropoulos, K., Evans-Axelsson, S., Franks, B., Fullwood, L., Horgan, D., Smith, E. J., Kiran, A., Kivinummi, K., Lambrecht, M., Lancet, D., Lindgren, P., Maclennan, S., Nogueira, M. M., Moen, F., Moinat, M., Papineni, K., Reich, C., Reiche, K., Rogiers, S., Sartini, C., van Bochove, K., van Diggelen, F., Van Hemelrijck, M., Van Poppel, H., Zong, J., N'Dow, J., Andersson, E., Arala, H., Auvinen, A., Bangma, C., Burke, D., Cardone, A., Casariego, J., Cuperus, G., Dabestani, S., Esperto, F., Fossati, N., Fridhammar, A., Gandaglia, G., Tandefelt, D. G., Horn, F., Huber, J., Hugosson, J., Huisman, H., Josefsson, A., Kilkku, O., Kreuz, M., Lardas, M., Lawson, J., Lefresne, F., Lejeune, S., Longden-Chapman, E., Mcvie, G., Moris, L., Mottet, N., Murtola, T., Nicholls, C., Pang, K. H., Pascoe, K., Picozzi, M., Plass, K., Pohjanjousi, P., Reaney, M., Remmers, S., Robinson, P., Schalken, J., Schravendeel, M., Seisen, T., Servan, A., Shiranov, K., Snijder, R., Steinbeisser, C., Taibi, N., Talala, K., Tilki, D., Van den Broeck, T., Vassilev, Z., Voima, O., Vradi, E., Waldeck, R., Weistra, W., Willemse, P. -P., Wirth, M., Wolfinger, R., and Kermani, N. Z.
- Abstract
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
- Published
- 2020
11. Impaired Development of Rat Liver Enzyme Activities at Birth after Irradiation in Utero
- Author
-
Smith, Carl Hugh and Shore, Moris L.
- Published
- 1966
- Full Text
- View/download PDF
12. Interference by X-Irradiation with the Induced Synthesis of Tryptophan Pyrrolase
- Author
-
Mishkin, E. Patricia and Shore, Moris L.
- Published
- 1968
- Full Text
- View/download PDF
13. The role of nuclear export in primary high-risk prostate cancer: A genomic analysis identifies XPO1 as potential therapeutic agent in high risk prostate cancer
- Author
-
Moris, L., primary, Van Den Broeck, T., additional, Buerki, C., additional, Davicioni, E., additional, Everaerts, W., additional, Handle, F., additional, Helsen, C., additional, Jacquemyn, M., additional, Landesman, Y., additional, Soenen, S., additional, Daelemans, D., additional, Joniau, S., additional, and Claessens, F., additional
- Published
- 2021
- Full Text
- View/download PDF
14. Diagnostic and prognostic factors in patients with prostate cancer
- Author
-
Beyer, K., primary, Moris, L., additional, Lardas, M., additional, Haire, A., additional, Barletta, F., additional, Scuderi, S., additional, Molnar, M., additional, Herrera, R., additional, Rauf, A., additional, Campi, R., additional, Greco, I.., additional, Shiranov, K., additional, Dabestani, S., additional, Van Den Broeck, T., additional, Gacci, M., additional, Gandaglia, G., additional, Omar, M.I., additional, Maclennan, S., additional, Roobol, M.J., additional, Zong, J., additional, Maclennan, S.J., additional, Collette, L., additional, Briganti, A., additional, Bjartell, A., additional, and Van Hemelrijck, M., additional
- Published
- 2021
- Full Text
- View/download PDF
15. Evaluation of oncological outcomes and data quality in studies assessing nerve sparing versus non-nerve sparing radical prostatectomy in non-metastatic prostate cancer: A systematic review
- Author
-
Moris, L., primary, Gandaglia, G., additional, Vilaseca, A., additional, Van Den Broeck, T., additional, Briers, E., additional, De Santis, M., additional, Gillessen, S., additional, Grivas, N., additional, Henry, A., additional, Lam, T.B., additional, Lardas, M., additional, Mason, M., additional, Oprea-Lager, D., additional, Ploussard, G., additional, Rouvière, O., additional, Schoots, I.G., additional, Van Der Poel, H., additional, Wiegel, T., additional, Willemse, P-P., additional, Grummet, J.P., additional, Tilke, D., additional, Van Den Bergh, R.C.N., additional, Cornford, P., additional, and Mottet, N., additional
- Published
- 2021
- Full Text
- View/download PDF
16. A systematic review on the impact of surgeon and hospital caseload volume on oncological and non-oncological outcomes after radical prostatectomy for non-metastatic prostate cancer
- Author
-
Van Den Broeck, T., primary, Oprea-Lager, D., additional, Moris, L., additional, Kailavasan, M., additional, Briers, E., additional, Cornford, P., additional, De Santis, M., additional, Gandaglia, G., additional, Gillessen Sommer, S., additional, Grummet, J.P., additional, Grivas, N., additional, Lam, T.B., additional, Lardas, M., additional, Liew, M., additional, Mason, M., additional, O’Hanlon, S., additional, Ploussard, G., additional, Rouvière, O., additional, Schoots, I., additional, Tilki, D., additional, Van Den Bergh, R.C.N., additional, Van Der Poel, H., additional, Wiegel, T., additional, Willemse, P., additional, and Mottet, N., additional
- Published
- 2021
- Full Text
- View/download PDF
17. The Key Role of Patient Involvement in the Development of Core Outcome Sets in Prostate Cancer
- Author
-
Beyer, K., MacLennan, S.J., Moris, L., Lardas, M., Mastris, K., Hooker, G., Greene, R., Briers, E., Omar, M.I., Healey, J., Tripathee, S., Gandaglia, G., Venderbos, L.D.F., Smith, E.J., Bjorkqvist, J., Asiimwe, A., Huber, J., Roobol, M.J., Zong, J., Bjartell, A., N'Dow, J., Briganti, A., Schalken, J.A., MacLennan, S., Hemelrijck, M. Van, Beyer, K., MacLennan, S.J., Moris, L., Lardas, M., Mastris, K., Hooker, G., Greene, R., Briers, E., Omar, M.I., Healey, J., Tripathee, S., Gandaglia, G., Venderbos, L.D.F., Smith, E.J., Bjorkqvist, J., Asiimwe, A., Huber, J., Roobol, M.J., Zong, J., Bjartell, A., N'Dow, J., Briganti, A., Schalken, J.A., MacLennan, S., and Hemelrijck, M. Van
- Abstract
Contains fulltext : 244306.pdf (Publisher’s version ) (Open Access), Patients are the stewards of their own care and hence their voice is important when designing and implementing research. Patients should be involved not only as participants in research that impacts their care, as the recipients of that care and any associated harms, but also as research collaborators in prioritising important questions from the patient perspective and designing the research and the ways in which is it most appropriate to involve patients. The PIONEER Consortium, an international multistakeholder collaboration lead by the European Association of Urology, has developed a core outcome set (COS) for localised and metastatic prostate cancer relevant to all stakeholders in particular patients. Throughout the work of PIONEER, patient representatives were involved as collaborators in setting the research agenda, and a wider group of patients was involved as participants in developing COSs, for instance in consensus meetings on choosing important outcomes and appropriate definitions. This publication showcases the process for COS development and highlights the most important recommendations to ultimately inform future research projects co-created between patients and other stakeholders. PATIENT SUMMARY: An important step in involving patients in the selection of outcomes for clinical trials, clinical audits, and real-world evidence is the development of a core outcome set (COS) that is relevant to all stakeholders. This report highlights the patient participation throughout our PIONEER COS development. TAKE HOME MESSAGE: An important step in involving patients in the selection of outcomes for clinical trials, clinical audits, and real-world evidence is to develop a core outcome set (COS) that is relevant to all stakeholders. As part of the work of the PIONEER Consortium, we aim to highlight the patient participation throughout our PIONEER COS development.
- Published
- 2021
18. Diagnostic and prognostic factors in patients with prostate cancer: a systematic review protocol
- Author
-
Beyer, K., Moris, L., Lardas, M., Haire, A., Barletta, F., Scuderi, S., Vradi, E., Gandaglia, G., Omar, M.I., MacLennan, S., Zong, J., Farahmand, B., MacLennan, S.J., Devecseri, Z., Asiimwe, A., Collette, L., Bjartell, A., Ndow, J., Schalken, J.A., Huisman, H.J., Briganti, A., Hemelrijck, M. Van, Beyer, K., Moris, L., Lardas, M., Haire, A., Barletta, F., Scuderi, S., Vradi, E., Gandaglia, G., Omar, M.I., MacLennan, S., Zong, J., Farahmand, B., MacLennan, S.J., Devecseri, Z., Asiimwe, A., Collette, L., Bjartell, A., Ndow, J., Schalken, J.A., Huisman, H.J., Briganti, A., and Hemelrijck, M. Van
- Abstract
Contains fulltext : 232893.pdf (Publisher’s version ) (Open Access), INTRODUCTION: As part of the PIONEER (Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe) Consortium, we will explore which diagnostic and prognostic factors (DPFs) are currently being researched to previously defined clinical and patient-reported outcomes for prostate cancer (PCa). METHODS AND ANALYSIS: This research project will follow the following four steps: (1) a broad systematic literature review of DPFs for all stages of PCa, covering evidence from 2014 onwards; (2) discussion of systematic review findings by a multidisciplinary expert panel; (3) risk of bias assessment and applicability with Prediction model Risk Of Bias Assessment Tool criteria, Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) and the Quality In Prognosis Studies tool (QUIPS) and (4) additional quantitative assessments if required. ETHICS AND DISSEMINATION: We aim to develop an online tool to present the DPFs identified in this research and make them available across all stakeholders. There are no ethical implications.
- Published
- 2021
19. P046 - PIONEER consensus on clinician reported outcome measurements
- Author
-
Beyer, K., Moris, L., Gandaglia, G., Lardas, M., Healey, J., Omar, M.I., Zong, J., Maclennan, S.J., Briganti, A., Van Hemelrijck, M., and Maclennan, S.
- Published
- 2020
- Full Text
- View/download PDF
20. Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
- Author
-
Hernandez, A, Green, J, Janmohamed, S, D'Agostino, R, Granger, C, Jones, N, Leiter, L, Rosenberg, A, Sigmon, K, Somerville, M, Thorpe, K, Mcmurray, J, Del Prato, S, Califf, R, Holman, R, Demets, D, Riddle, M, Goodman, S, Mcguire, D, Alexander, K, Devore, A, Melloni, C, Patel, C, Kong, D, Bloomfield, G, Roe, M, Tricoci, P, Harrison, R, Lopes, R, Mathews, R, Mehta, R, Schuyler Jones, W, Vemulapalli, S, Povsic, T, Eapen, Z, Dombrowski, K, Kolls, B, Jordan, D, Ambrosy, A, Greene, S, Mandawat, A, Shavadia, J, Cooper, L, Sharma, A, Guimaraes, P, Friedman, D, Wilson, M, Endsley, P, Gentry, T, Collier, J, Perez, K, James, K, Roush, J, Pope, C, Howell, C, Johnson, M, Bailey, M, Cole, J, Akers, T, Vandyne, B, Thomas, B, Rich, J, Bartone, S, Beaulieu, G, Brown, K, Chau, T, Christian, T, Coker, R, Greene, D, Haddock, T, Jenkins, W, Haque, G, Marquess, M, Pesarchick, J, Rethaford, R, Stone, A, Al Kawas, F, Anderson, M, Enns, R, Sinay, I, Mathieu, C, Yordanov, V, Hramiak, I, Haluzik, M, Galatius, S, Guerci, B, Nauck, M, Migdalis, I, Tan, C, Kocsis, G, Giaccari, A, Lee, M, Munoz, E, Cornel, J, Birkeland, K, Pinto, M, Tirador, L, Olesinska-Mader, M, Shestakova, M, Distiller, L, Lopez-Sendon, J, Eliasson, B, Chiang, C, Srimahachota, S, Mankovsky, B, Bethel, M, Dungan, K, Kosiborod, M, Alvarisqueta, A, Baldovino, J, Besada, D, Calella, P, Cantero, M, Castano, P, Chertkoff, A, Cuadrado, J, De Loredo, L, Dominguez, A, Espanol, M, Finkelstein, H, Frechtel, G, Fretes, J, Garrido Santos, N, Gonzalez, J, Litvak, M, Loureyro, J, Maffei, L, Maldonado, N, Mohr Gasparini, D, Orio, S, Perez Manghi, F, Rodriguez Papini, N, Sala, J, Schygiel, P, Sposetti, G, Ulla, M, Verra, F, Zabalua, S, Zaidman, C, Crenier, L, Debroye, C, Duyck, F, Scheen, A, Van Gaal, L, Vercammen, C, Damyanova, V, Dimitrov, S, Kovacheva, S, Lozanov, L, Margaritov, V, Mihaylova-Shumkova, R, Nikolaeva, A, Stoyanova, Z, Akhras, R, Beaudry, Y, Bedard, J, Berlingieri, J, Chehayeb, R, Cheung, S, Conway, J, Cusson, J, Della Siega, A, Dumas, R, Dzongowski, P, Ferguson, M, Gaudet, D, Grondin, F, Gupta, A, Gupta, M, Halperin, F, Houle, P, Jones, M, Kouz, S, Kovacs, C, Landry, D, Lonn, E, O'Mahony, W, Peterson, S, Reich, D, Rosenbloom, A, St-Maurice, F, Tugwell, B, Vizel, S, Woo, V, Brychta, T, Cech, V, Dvorakova, E, Edelsberger, T, Halciakova, K, Krizova, J, Lastuvka, J, Piperek, M, Prymkova, V, Raclavska, L, Silhova, E, Urbanek, R, Vrkoc, J, Andersen, U, Bronnum-Schou, J, Hove, J, Jensen, J, Kober, L, Kristiansen, O, Lund, P, Melchior, T, Nyvad, O, Schou, M, Boye, A, Cadinot, D, Gouet, D, Henry, P, Kessler, L, Lalau, J, Petit, C, Thuan, J, Voinot, C, Vouillarmet, J, Axthelm, C, Berger, D, Bieler, T, Birkenfeld, A, Bott, J, Busch, K, Caca, K, Chevts, J, Donaubauer, T, Erlinger, R, Funke, K, Grosskopf, J, Hagenow, A, Hamann, M, Hartard, M, Heymer, P, Huppertz, W, Illies, G, Jacob, S, Jung, T, Kahrmann, G, Kast, P, Kellerer, M, Kempe, H, Khariouzov, A, Klausmann, G, Klein, C, Kleinecke-Pohl, U, Kleinertz, K, Koch, T, Kosch, C, Lorra, B, Luedemann, J, Luttermann, M, Maxeiner, S, Milek, K, Moelle, A, Neumann, G, Nischik, R, Oehrig-Pohl, E, Plassmann, G, Pohlmeier, L, Proepper, F, Regner, S, Rieker, W, Rose, L, Samer, H, Sauter, J, Schaper, F, Schiffer, C, Schmidt, J, Scholz, B, Schulze, J, Segner, A, Seufert, J, Sigal, H, Steindorf, J, Stockhausen, J, Stuebler, P, Taeschner, H, Tews, D, Tschoepe, D, Wilhelm, K, Zeller-Stefan, H, Avramidis, I, Bousboulas, S, Bristianou, M, Dimitriadis, G, Elisaf, M, Kotsa, K, Melidonis, A, Mitrakou, A, Pagkalos, E, Papanas, N, Pappas, A, Sampanis, C, Tentolouris, N, Tsapas, A, Tzatzagou, G, Ozaki, R, Hajdu, C, Harcsa, E, Konyves, L, Mucsi, J, Pauker, Z, Petro, G, Ples, Z, Revesz, K, Sandor, V, Vass, V, Avogaro, A, Boemi, M, Bonadonna, R, Consoli, A, De Cosmo, S, Di Bartolo, P, Dotta, F, Frontoni, S, Galetta, M, Gambineri, A, Gazzaruso, C, Giorgino, F, Lauro, D, Orsi, E, Paolisso, G, Perriello, G, Piatti, P, Pontiroli, A, Ponzani, P, Rivellese, A, Sesti, G, Tonolo, G, Trevisan, R, Ahn, C, Baik, S, Cha, B, Chung, C, Jang, H, Kim, C, Kim, H, Kim, I, Lee, E, Lee, H, Lee, K, Moon, K, Namgung, J, Park, K, Yoo, S, Yu, J, Llamas, E, Cervantes-Escarcega, J, Flota-Cervera, L, Gonzalez-Gonzalez, J, Pascoe-Gonzalez, S, Pelayo-Orozco, E, Ramirez-Diaz, S, Saldana-Mendoza, A, Jerjes-Diaz, C, Torres-Colores, J, Vidrio-Velazquez, M, Villagordoa-Mesa, J, Beijerbacht, H, Groutars, R, Hoek, B, Hoogslag, P, Kooy, A, Kragten, J, Lieverse, A, Swart, H, Viergever, E, Ahlqvist, J, Cooper, J, Gulseth, H, Guttormsen, G, Wium, C, Arbanil, H, Calderon, J, Camacho, L, Espinoza, A, Garrido, E, Luna, A, Manrique, H, Revoredo, F, Gonzales, R, Rincon, L, Zubiate, C, Ebo, G, Morales-Palomares, E, Arciszewska, M, Banach, M, Bijata-Bronisz, R, Derezinski, T, Gadzinski, W, Gajek, J, Klodawska, K, Krzyzagorska, E, Madej, A, Miekus, P, Opiela, J, Romanczuk, P, Siegel, A, Skokowska, E, Stankiewicz, A, Stasinska, T, Trznadel-Morawska, I, Witek, R, Aksentyev, S, Bondar, I, Demidova, I, Dreval, A, Ershova, O, Galstyan, G, Garganeeva, A, Izmozherova, N, Karetnikova, V, Kharakhulakh, M, Khokhlov, A, Kobalava, Z, Koshelskaya, O, Kosmacheva, E, Kostin, V, Koziolova, N, Kuzin, A, Lesnov, V, Lysenko, T, Markov, V, Mayorov, A, Moiseev, S, Myasoedova, S, Petunina, N, Rebrov, A, Ruyatkina, L, Samoylova, J, Sazonova, O, Shilkina, N, Sokolova, N, Vasilevskaya, O, Verbovaya, N, Vishneva, E, Vorobyev, S, Vorokhobina, N, Zanozina, O, Zhdanova, E, Zykova, T, Burgess, L, Coetzee, K, Dawood, S, Lombard, L, Makotoko, E, Moodley, R, Oosthuysen, W, Sarvan, M, Calvo Gomez, C, Cano Rodriguez, I, Castro Conde, A, Cequier Fillat, A, Cuatrecasas Cambra, G, de Alvaro Moreno, F, De Teresa Parreno, L, Delgado Lista, J, Dominguez Escribano, J, Duran Garcia, S, Elvira Gonzalez, J, Fernandez Rodriguez, J, Goday Arno, A, Gomez Huelgas, R, Gonzalez Juanatey, J, Hernandez Mijares, A, Jimenez Diaz, V, Jodar Gimeno, E, Lucas Morante, T, Marazuela, M, Martell Claros, N, Mauricio Puente, D, Mena Ribas, E, Merino Torres, J, Mezquita Raya, P, Nubiola Calonge, A, Ordonez Sanchez, X, Pascual Izuel, J, Perea Castilla, V, Perez Perez, A, Perez Soto, I, Quesada Charneco, M, Quesada Simon, A, Redon Mas, J, Rego Iraeta, A, Rodriguez Alvarez, M, Rodriguez Rodriguez, I, Saban Ruiz, J, Soto Gonzalez, A, Tinahones Madueno, F, Trescoli Serrano, C, Ulied Arminana, A, Bachus, E, Berndtsson Blom, K, Eliasson, K, Koskinen, P, Larnefeldt, H, Lif-Tiberg, C, Linderfalk, C, Lund, G, Lundman, P, Moris, L, Olsson, A, Salmonsson, S, Sanmartin Berglund, J, Sjoberg, F, Soderberg, S, Torstensson, I, Chen, J, Tien, K, Tseng, S, Tu, S, Wang, C, Wang, J, Phrommintikul, A, Yamwong, S, Jintapakorn, W, Hutayanon, P, Sansanayudh, N, Bazhan, L, Fushtey, I, Grachova, M, Katerenchuk, V, Korpachev, V, Kravchun, N, Larin, O, Mykhalchyshyn, G, Myshanych, H, Oleksyk, O, Orlenko, V, Pashkovska, N, Pertseva, N, Petrosyan, O, Smirnov, I, Vlasenko, M, Zlova, T, Aye, M, Baksi, A, Balasubramani, M, Beboso, R, Blagden, M, Bundy, C, Cookson, T, Copland, A, Emslie-Smith, A, Green, F, Gunstone, A, Issa, B, Jackson-Voyzey, E, Johnson, A, Maclean, M, Mcknight, J, Muzulu, S, O'Connell, I, Oyesile, B, Patterson, C, Pearson, E, Philip, S, Smith, P, Sukumaran, U, Abbas, J, Aggarwala, G, Akhter, F, Andersen, J, Anglade, M, Argoud, G, Ariani, M, Ashdji, R, Bakhtari, L, Banerjee, S, Bartlett, A, Baum, H, Bays, H, Beasley, R, Belfort de Aguiar, R, Benjamin, S, Bhagwat, R, Bhargava, A, Bode, B, Bratcher, C, Briskin, T, Brockmyre, A, Broughton, R, Brown, J, Budhraja, M, Cannon, K, Carr, J, Cathcart, H, Cavale, A, Chaykin, L, Cheung, D, Childress, R, Cohen, A, Condit, J, Cooksey, E, Cornett, G, Dauber, I, Davila, W, De Armas, L, Dean, J, Detweiler, R, Diaz, E, Di Giovanna, M, Dor, I, Drummond, W, Eagerton, D, Earl, J, Eaton, C, Ellison, H, Farris, N, Fiel, T, Firek, A, First, B, Forgosh, L, French, W, Gandy, W, Garcia, R, Gill, S, Gordon, M, Guice, M, Gummadi, S, Hackenyos, J, Hairston, K, Hanson, L, Harrison, L, Hartman, I, Heitner, J, Hejeebu, S, Hermany, P, Hernandez-Cassis, C, Hidalgo, H, Higgins, A, Ibrahim, H, Jacobs, S, Johnson, D, Joshi, P, Kaster, S, Kellum, D, Kim, E, Kirby, W, Knouse, A, Kulback, S, Kumar, M, Kuruvanka, T, Labroo, A, Lasswell, W, Lentz, J, Lenzmeier, T, Lewis, D, Li, Z, Lillestol, M, Little, R, Lorraine, R, McKeown-Biagas, C, Mcneill, R, Mehta, A, Miller, A, Moran, J, Morawski, E, Nadar, V, O'Connor, T, Odio, A, Parker, R, Patel, R, Phillips, L, Raad, G, Rahman, A, Raikhel, M, Raisinghani, A, Rajan, R, Rasouli, N, Rauzi, F, Rohr, K, Roseman, H, Rovner, S, Saba, F, Sachson, R, Schabauer, A, Schneider, R, Schuchard, T, Sensenbrenner, J, Shlesinger, Y, Singh, N, Sivalingam, K, Stonesifer, L, Storey, D, Suh, D, Tahir, M, Tan, A, Tan, M, Taylon, A, Thakkar, M, Tripathy, D, Uwaifo, G, Vedere, A, Venugopal, C, Vo, A, Welch, M, Welker, J, White, A, Willis, J, Wynne, A, Yazdani, S, Price, L, Lokhngina, Y, Xing, W, Overton, R, Stewart, M, Stead, J, Lindsay, A, Patel, V, Ross, J, Soffer, J, Daga, S, Sowell, M, Patel, P, Garvey, L, Ackert, J, Abraham, S, Sabol, M, Altobelli, D, Ha, J, Kulkarni, M, Noronha, D, Casson, E, Zang, E, Sandhu, C, Kumar, R, Chen, D, Taft, L, Ye, J, Shannon, J, Wilson, T, Babi, C, Miller, D, Russell, R, Bull, G, Hereghty, B, Fernandez-Salazar, E, Longley, T, Donaldson, J, Jarosz, M, Murphy, K, Adams, P, James, R, Richards, J, Sedani, S, Althouse, D, Watson, D, Lorimer, J, Lauder, S, Schultheis, R, Womer, T, Wraight, E, Li, W, Price-Olsen, E, Watson, A, Kelly, A, Mclaughlin, P, Fleming, J, Schubert, J, Schleiden, D, Harris, T, Prakash, R, Breneman, J, Deshpande, S, Saswadkar, A, Kumari, A, Shitut, A, Raorane, A, Karmalkar, A, Mhambrey, A, Bhosale, A, Vaphare, A, Patil, A, Khandelwal, C, Shaik, F, Nadar, M, Karka, M, Kadgaonkar, N, Gupta, N, Aher, N, Potnis, O, Naicker, P, Shinde, R, Sharma, R, Godse, R, Solanki, S, Sahu, S, Dumbre, S, Kumar, S, Patil, S, Mandal, T, Hernandez A. F., Green J. B., Janmohamed S., D'Agostino R. B., Granger C. B., Jones N. P., Leiter L. A., Rosenberg A. E., Sigmon K. N., Somerville M. C., Thorpe K. M., McMurray J. J. V., Del Prato S., Califf R. M., Holman R., DeMets D., Riddle M., Goodman S., McGuire D., Alexander K., Devore A., Melloni C., Patel C., Kong D., Bloomfield G., Roe M., Tricoci P., Harrison R., Lopes R., Mathews R., Mehta R., Schuyler Jones W., Vemulapalli S., Povsic T., Eapen Z., Dombrowski K., Kolls B., Jordan D., Ambrosy A., Greene S., Mandawat A., Shavadia J., Cooper L., Sharma A., Guimaraes P., Friedman D., Wilson M., Endsley P., Gentry T., Collier J., Perez K., James K., Roush J., Pope C., Howell C., Johnson M., Bailey M., Cole J., Akers T., Vandyne B., Thomas B., Rich J., Bartone S., Beaulieu G., Brown K., Chau T., Christian T., Coker R., Greene D., Haddock T., Jenkins W., Haque G., Marquess M., Pesarchick J., Rethaford R., Stone A., Al Kawas F., Anderson M., Enns R., Sinay I., Mathieu C., Yordanov V., Hramiak I., Haluzik M., Galatius S., Guerci B., Nauck M., Migdalis I., Tan C. B. K., Kocsis G., Giaccari A., Lee M. K., Munoz E. G. C., Cornel J., Birkeland K., Pinto M., Tirador L., Olesinska-Mader M., Shestakova M., Distiller L., Lopez-Sendon J., Eliasson B., Chiang C. -E., Srimahachota S., Mankovsky B., Bethel M. A., Dungan K., Kosiborod M., Alvarisqueta A., Baldovino J., Besada D., Calella P., Cantero M. C., Castano P., Chertkoff A., Cuadrado J., De Loredo L., Dominguez A., Espanol M. V., Finkelstein H., Frechtel G., Fretes J., Garrido Santos N., Gonzalez J., Litvak M., Loureyro J., Maffei L., Maldonado N., Mohr Gasparini D., Orio S., Perez Manghi F., Rodriguez Papini N., Sala J., Schygiel P., Sposetti G., Ulla M., Verra F., Zabalua S., Zaidman C., Crenier L., Debroye C., Duyck F., Scheen A., Van Gaal L., Vercammen C., Damyanova V., Dimitrov S., Kovacheva S., Lozanov L., Margaritov V., Mihaylova-Shumkova R., Nikolaeva A., Stoyanova Z., Akhras R., Beaudry Y., Bedard J., Berlingieri J., Chehayeb R., Cheung S., Conway J., Cusson J., Della Siega A., Dumas R., Dzongowski P., Ferguson M., Gaudet D., Grondin F., Gupta A., Gupta M., Halperin F., Houle P. -A., Jones M., Kouz S., Kovacs C., Landry D., Lonn E., O'Mahony W., Peterson S., Reich D., Rosenbloom A., St-Maurice F., Tugwell B., Vizel S., Woo V., Brychta T., Cech V., Dvorakova E., Edelsberger T., Halciakova K., Krizova J., Lastuvka J., Piperek M., Prymkova V., Raclavska L., Silhova E., Urbanek R., Vrkoc J., Andersen U., Bronnum-Schou J., Hove J., Jensen J. S., Kober L., Kristiansen O. P., Lund P., Melchior T., Nyvad O., Schou M., Boye A., Cadinot D., Gouet D., Henry P., Kessler L., Lalau J. -D., Petit C., Thuan J. -F., Voinot C., Vouillarmet J., Axthelm C., Berger D., Bieler T., Birkenfeld A., Bott J., Busch K., Caca K., Chevts J., Donaubauer T., Erlinger R., Funke K., Grosskopf J., Hagenow A., Hamann M., Hartard M., Heymer P., Huppertz W., Illies G., Jacob S., Jung T., Kahrmann G., Kast P., Kellerer M., Kempe H. -P., Khariouzov A., Klausmann G., Klein C., Kleinecke-Pohl U., Kleinertz K., Koch T., Kosch C., Lorra B., Luedemann J., Luttermann M., Maxeiner S., Milek K., Moelle A., Neumann G., Nischik R., Oehrig-Pohl E., Plassmann G., Pohlmeier L., Proepper F., Regner S., Rieker W., Rose L., Samer H., Sauter J., Schaper F., Schiffer C., Schmidt J., Scholz B. -M., Schulze J., Segner A., Seufert J., Sigal H., Steindorf J., Stockhausen J., Stuebler P., Taeschner H., Tews D., Tschoepe D., Wilhelm K., Zeller-Stefan H., Avramidis I., Bousboulas S., Bristianou M., Dimitriadis G., Elisaf M., Kotsa K., Melidonis A., Mitrakou A., Pagkalos E., Papanas N., Pappas A., Sampanis C., Tentolouris N., Tsapas A., Tzatzagou G., Ozaki R., Hajdu C., Harcsa E., Konyves L., Mucsi J., Pauker Z., Petro G., Ples Z., Revesz K., Sandor V., Vass V., Avogaro A., Boemi M., Bonadonna R., Consoli A., De Cosmo S., Di Bartolo P., Dotta F., Frontoni S., Galetta M., Gambineri A., Gazzaruso C., Giorgino F., Lauro D., Orsi E., Paolisso G., Perriello G., Piatti P., Pontiroli A., Ponzani P., Rivellese A. A., Sesti G., Tonolo G., Trevisan R., Ahn C. W., Baik S. -H., Cha B. -S., Chung C. -H., Jang H. C., Kim C. -J., Kim H. S., Kim I. J., Lee E. Y., Lee H. W., Lee K. -W., Moon K. -W., Namgung J., Park K. S., Yoo S. J., Yu J., Llamas E. -A. B., Cervantes-Escarcega J. -L., Flota-Cervera L. F., Gonzalez-Gonzalez J. G., Pascoe-Gonzalez S., Pelayo-Orozco E. S., Ramirez-Diaz S. -P., Saldana-Mendoza A., Jerjes-Diaz C. S., Torres-Colores J. J., Vidrio-Velazquez M., Villagordoa-Mesa J., Beijerbacht H. P., Groutars R. G. E. J., Hoek B. A., Hoogslag P. A. M., Kooy A., Kragten J. A., Lieverse A. G., Swart H. P., Viergever E. P., Ahlqvist J., Cooper J., Gulseth H., Guttormsen G., Wium C., Arbanil H., Calderon J., Camacho L., Espinoza A. D., Garrido E., Luna A., Manrique H., Revoredo F. M., Gonzales R. V., Rincon L. Z., Zubiate C., Ebo G., Morales-Palomares E., Arciszewska M., Banach M., Bijata-Bronisz R., Derezinski T., Gadzinski W., Gajek J., Klodawska K., Krzyzagorska E., Madej A., Miekus P., Opiela J., Romanczuk P., Siegel A., Skokowska E., Stankiewicz A., Stasinska T., Trznadel-Morawska I., Witek R., Aksentyev S., Bondar I., Demidova I., Dreval A., Ershova O., Galstyan G., Garganeeva A., Izmozherova N., Karetnikova V., Kharakhulakh M., Khokhlov A., Kobalava Z., Koshelskaya O., Kosmacheva E., Kostin V., Koziolova N., Kuzin A., Lesnov V., Lysenko T., Markov V., Mayorov A., Moiseev S., Myasoedova S., Petunina N., Rebrov A., Ruyatkina L., Samoylova J., Sazonova O., Shilkina N., Sokolova N., Vasilevskaya O., Verbovaya N., Vishneva E., Vorobyev S., Vorokhobina N., Zanozina O., Zhdanova E., Zykova T., Burgess L., Coetzee K., Dawood S., Lombard L., Makotoko E., Moodley R., Oosthuysen W., Sarvan M., Calvo Gomez C., Cano Rodriguez I., Castro Conde A., Cequier Fillat A., Cuatrecasas Cambra G., de Alvaro Moreno F., De Teresa Parreno L., Delgado Lista J., Dominguez Escribano J. R., Duran Garcia S., Elvira Gonzalez J., Fernandez Rodriguez J. M., Goday Arno A., Gomez Huelgas R., Gonzalez Juanatey J. R., Hernandez Mijares A., Jimenez Diaz V. A., Jodar Gimeno E., Lucas Morante T., Marazuela M., Martell Claros N., Mauricio Puente D., Mena Ribas E., Merino Torres J. F., Mezquita Raya P., Nubiola Calonge A., Ordonez Sanchez X., Pascual Izuel J. M., Perea Castilla V., Perez Perez A., Perez Soto I., Quesada Charneco M., Quesada Simon A., Redon Mas J., Rego Iraeta A., Rodriguez Alvarez M., Rodriguez Rodriguez I., Saban Ruiz J., Soto Gonzalez A., Tinahones Madueno F., Trescoli Serrano C., Ulied Arminana A., Bachus E., Berndtsson Blom K., Eliasson K., Koskinen P., Larnefeldt H., Lif-Tiberg C., Linderfalk C., Lund G., Lundman P., Moris L., Olsson A., Salmonsson S., Sanmartin Berglund J., Sjoberg F., Soderberg S., Torstensson I., Chen J. -F., Tien K. J., Tseng S. -T., Tu S. -T., Wang C. -Y., Wang J. -H., Phrommintikul A., Yamwong S., Jintapakorn W., Hutayanon P., Sansanayudh N., Bazhan L., Fushtey I., Grachova M., Katerenchuk V., Korpachev V., Kravchun N., Larin O., Mykhalchyshyn G., Myshanych H., Oleksyk O., Orlenko V., Pashkovska N., Pertseva N., Petrosyan O., Smirnov I., Vlasenko M., Zlova T., Aye M., Baksi A., Balasubramani M., Beboso R., Blagden M., Bundy C., Cookson T., Copland A., Emslie-Smith A., Green F., Gunstone A., Issa B., Jackson-Voyzey E., Johnson A., Maclean M., McKnight J., Muzulu S., O'Connell I., Oyesile B., Patterson C., Pearson E., Philip S., Smith P., Sukumaran U., Abbas J., Aggarwala G., Akhter F., Andersen J., Anglade M., Argoud G., Ariani M., Ashdji R., Bakhtari L., Banerjee S., Bartlett A., Baum H., Bays H., Beasley R., Belfort de Aguiar R., Benjamin S., Bhagwat R., Bhargava A., Bode B., Bratcher C., Briskin T., Brockmyre A., Broughton R., Brown J., Budhraja M., Cannon K., Carr J., Cathcart H., Cavale A., Chaykin L., Cheung D., Childress R., Cohen A., Condit J., Cooksey E., Cornett G. M., Dauber I., Davila W., De Armas L., Dean J., Detweiler R., Diaz E., Di Giovanna M., Dor I., Drummond W., Eagerton D., Earl J., Eaton C., Ellison H., Farris N., Fiel T., Firek A., First B., Forgosh L., French W., Gandy W., Garcia R., Gill S., Gordon M., Guice M., Gummadi S., Hackenyos J., Hairston K., Hanson L., Harrison L., Hartman I., Heitner J., Hejeebu S., Hermany P., Hernandez-Cassis C., Hidalgo H., Higgins A., Ibrahim H., Jacobs S., Johnson D., Joshi P., Kaster S., Kellum D., Kim C., Kim E., Kirby W., Knouse A., Kulback S., Kumar M., Kuruvanka T., Labroo A., Lasswell W., Lentz J., Lenzmeier T., Lewis D., Li Z., Lillestol M., Little R., Lorraine R., McKeown-Biagas C., McNeill R., Mehta A., Miller A., Moran J., Morawski E., Nadar V., O'Connor T., Odio A., Parker R., Patel R., Phillips L., Raad G., Rahman A., Raikhel M., Raisinghani A., Rajan R., Rasouli N., Rauzi F., Rohr K., Roseman H., Rovner S., Saba F., Sachson R., Schabauer A., Schneider R., Schuchard T., Sensenbrenner J., Shlesinger Y., Singh N., Sivalingam K., Stonesifer L., Storey D., Suh D., Tahir M., Tan A., Tan M., Taylon A., Thakkar M., Tripathy D., Uwaifo G., Vedere A., Venugopal C., Vo A., Welch M., Welker J., White A., Willis J., Wynne A., Yazdani S., Price L., Lokhngina Y., Xing W., Overton R., Stewart M., Stead J., Lindsay A., Patel V., Ross J., Soffer J., Daga S., Sowell M., Patel P., Garvey L., Ackert J., Abraham S., Sabol M. B., Altobelli D., Ha J., Kulkarni M., Noronha D., Casson E., Zang E., Sandhu C., Kumar R., Chen D., Taft L., Ye J., Shannon J., Wilson T., Babi C., Miller D., Russell R., Bull G., Hereghty B., Fernandez-Salazar E., Longley T., Donaldson J., Jarosz M., Murphy K., Adams P., James R., Richards J., Sedani S., Althouse D., Watson D., Lorimer J., Lauder S., Schultheis R., Womer T., Wraight E., Li W., Price-Olsen E., Watson A., Kelly A., McLaughlin P., Fleming J., Schubert J., Schleiden D., Harris T., Prakash R., Breneman J., Deshpande S., Saswadkar A., Kumari A., Shitut A., Raorane A., Karmalkar A., Mhambrey A., Bhosale A., Vaphare A., Patil A. P., Khandelwal C., Shaik F., Nadar M., Karka M., Kadgaonkar N., Gupta N., Aher N., Potnis O., Naicker P., Shinde R., Sharma R., Godse R., Solanki S., Sahu S., Dumbre S., Kumar S., Patil S., Mandal T., Hernandez, A, Green, J, Janmohamed, S, D'Agostino, R, Granger, C, Jones, N, Leiter, L, Rosenberg, A, Sigmon, K, Somerville, M, Thorpe, K, Mcmurray, J, Del Prato, S, Califf, R, Holman, R, Demets, D, Riddle, M, Goodman, S, Mcguire, D, Alexander, K, Devore, A, Melloni, C, Patel, C, Kong, D, Bloomfield, G, Roe, M, Tricoci, P, Harrison, R, Lopes, R, Mathews, R, Mehta, R, Schuyler Jones, W, Vemulapalli, S, Povsic, T, Eapen, Z, Dombrowski, K, Kolls, B, Jordan, D, Ambrosy, A, Greene, S, Mandawat, A, Shavadia, J, Cooper, L, Sharma, A, Guimaraes, P, Friedman, D, Wilson, M, Endsley, P, Gentry, T, Collier, J, Perez, K, James, K, Roush, J, Pope, C, Howell, C, Johnson, M, Bailey, M, Cole, J, Akers, T, Vandyne, B, Thomas, B, Rich, J, Bartone, S, Beaulieu, G, Brown, K, Chau, T, Christian, T, Coker, R, Greene, D, Haddock, T, Jenkins, W, Haque, G, Marquess, M, Pesarchick, J, Rethaford, R, Stone, A, Al Kawas, F, Anderson, M, Enns, R, Sinay, I, Mathieu, C, Yordanov, V, Hramiak, I, Haluzik, M, Galatius, S, Guerci, B, Nauck, M, Migdalis, I, Tan, C, Kocsis, G, Giaccari, A, Lee, M, Munoz, E, Cornel, J, Birkeland, K, Pinto, M, Tirador, L, Olesinska-Mader, M, Shestakova, M, Distiller, L, Lopez-Sendon, J, Eliasson, B, Chiang, C, Srimahachota, S, Mankovsky, B, Bethel, M, Dungan, K, Kosiborod, M, Alvarisqueta, A, Baldovino, J, Besada, D, Calella, P, Cantero, M, Castano, P, Chertkoff, A, Cuadrado, J, De Loredo, L, Dominguez, A, Espanol, M, Finkelstein, H, Frechtel, G, Fretes, J, Garrido Santos, N, Gonzalez, J, Litvak, M, Loureyro, J, Maffei, L, Maldonado, N, Mohr Gasparini, D, Orio, S, Perez Manghi, F, Rodriguez Papini, N, Sala, J, Schygiel, P, Sposetti, G, Ulla, M, Verra, F, Zabalua, S, Zaidman, C, Crenier, L, Debroye, C, Duyck, F, Scheen, A, Van Gaal, L, Vercammen, C, Damyanova, V, Dimitrov, S, Kovacheva, S, Lozanov, L, Margaritov, V, Mihaylova-Shumkova, R, Nikolaeva, A, Stoyanova, Z, Akhras, R, Beaudry, Y, Bedard, J, Berlingieri, J, Chehayeb, R, Cheung, S, Conway, J, Cusson, J, Della Siega, A, Dumas, R, Dzongowski, P, Ferguson, M, Gaudet, D, Grondin, F, Gupta, A, Gupta, M, Halperin, F, Houle, P, Jones, M, Kouz, S, Kovacs, C, Landry, D, Lonn, E, O'Mahony, W, Peterson, S, Reich, D, Rosenbloom, A, St-Maurice, F, Tugwell, B, Vizel, S, Woo, V, Brychta, T, Cech, V, Dvorakova, E, Edelsberger, T, Halciakova, K, Krizova, J, Lastuvka, J, Piperek, M, Prymkova, V, Raclavska, L, Silhova, E, Urbanek, R, Vrkoc, J, Andersen, U, Bronnum-Schou, J, Hove, J, Jensen, J, Kober, L, Kristiansen, O, Lund, P, Melchior, T, Nyvad, O, Schou, M, Boye, A, Cadinot, D, Gouet, D, Henry, P, Kessler, L, Lalau, J, Petit, C, Thuan, J, Voinot, C, Vouillarmet, J, Axthelm, C, Berger, D, Bieler, T, Birkenfeld, A, Bott, J, Busch, K, Caca, K, Chevts, J, Donaubauer, T, Erlinger, R, Funke, K, Grosskopf, J, Hagenow, A, Hamann, M, Hartard, M, Heymer, P, Huppertz, W, Illies, G, Jacob, S, Jung, T, Kahrmann, G, Kast, P, Kellerer, M, Kempe, H, Khariouzov, A, Klausmann, G, Klein, C, Kleinecke-Pohl, U, Kleinertz, K, Koch, T, Kosch, C, Lorra, B, Luedemann, J, Luttermann, M, Maxeiner, S, Milek, K, Moelle, A, Neumann, G, Nischik, R, Oehrig-Pohl, E, Plassmann, G, Pohlmeier, L, Proepper, F, Regner, S, Rieker, W, Rose, L, Samer, H, Sauter, J, Schaper, F, Schiffer, C, Schmidt, J, Scholz, B, Schulze, J, Segner, A, Seufert, J, Sigal, H, Steindorf, J, Stockhausen, J, Stuebler, P, Taeschner, H, Tews, D, Tschoepe, D, Wilhelm, K, Zeller-Stefan, H, Avramidis, I, Bousboulas, S, Bristianou, M, Dimitriadis, G, Elisaf, M, Kotsa, K, Melidonis, A, Mitrakou, A, Pagkalos, E, Papanas, N, Pappas, A, Sampanis, C, Tentolouris, N, Tsapas, A, Tzatzagou, G, Ozaki, R, Hajdu, C, Harcsa, E, Konyves, L, Mucsi, J, Pauker, Z, Petro, G, Ples, Z, Revesz, K, Sandor, V, Vass, V, Avogaro, A, Boemi, M, Bonadonna, R, Consoli, A, De Cosmo, S, Di Bartolo, P, Dotta, F, Frontoni, S, Galetta, M, Gambineri, A, Gazzaruso, C, Giorgino, F, Lauro, D, Orsi, E, Paolisso, G, Perriello, G, Piatti, P, Pontiroli, A, Ponzani, P, Rivellese, A, Sesti, G, Tonolo, G, Trevisan, R, Ahn, C, Baik, S, Cha, B, Chung, C, Jang, H, Kim, C, Kim, H, Kim, I, Lee, E, Lee, H, Lee, K, Moon, K, Namgung, J, Park, K, Yoo, S, Yu, J, Llamas, E, Cervantes-Escarcega, J, Flota-Cervera, L, Gonzalez-Gonzalez, J, Pascoe-Gonzalez, S, Pelayo-Orozco, E, Ramirez-Diaz, S, Saldana-Mendoza, A, Jerjes-Diaz, C, Torres-Colores, J, Vidrio-Velazquez, M, Villagordoa-Mesa, J, Beijerbacht, H, Groutars, R, Hoek, B, Hoogslag, P, Kooy, A, Kragten, J, Lieverse, A, Swart, H, Viergever, E, Ahlqvist, J, Cooper, J, Gulseth, H, Guttormsen, G, Wium, C, Arbanil, H, Calderon, J, Camacho, L, Espinoza, A, Garrido, E, Luna, A, Manrique, H, Revoredo, F, Gonzales, R, Rincon, L, Zubiate, C, Ebo, G, Morales-Palomares, E, Arciszewska, M, Banach, M, Bijata-Bronisz, R, Derezinski, T, Gadzinski, W, Gajek, J, Klodawska, K, Krzyzagorska, E, Madej, A, Miekus, P, Opiela, J, Romanczuk, P, Siegel, A, Skokowska, E, Stankiewicz, A, Stasinska, T, Trznadel-Morawska, I, Witek, R, Aksentyev, S, Bondar, I, Demidova, I, Dreval, A, Ershova, O, Galstyan, G, Garganeeva, A, Izmozherova, N, Karetnikova, V, Kharakhulakh, M, Khokhlov, A, Kobalava, Z, Koshelskaya, O, Kosmacheva, E, Kostin, V, Koziolova, N, Kuzin, A, Lesnov, V, Lysenko, T, Markov, V, Mayorov, A, Moiseev, S, Myasoedova, S, Petunina, N, Rebrov, A, Ruyatkina, L, Samoylova, J, Sazonova, O, Shilkina, N, Sokolova, N, Vasilevskaya, O, Verbovaya, N, Vishneva, E, Vorobyev, S, Vorokhobina, N, Zanozina, O, Zhdanova, E, Zykova, T, Burgess, L, Coetzee, K, Dawood, S, Lombard, L, Makotoko, E, Moodley, R, Oosthuysen, W, Sarvan, M, Calvo Gomez, C, Cano Rodriguez, I, Castro Conde, A, Cequier Fillat, A, Cuatrecasas Cambra, G, de Alvaro Moreno, F, De Teresa Parreno, L, Delgado Lista, J, Dominguez Escribano, J, Duran Garcia, S, Elvira Gonzalez, J, Fernandez Rodriguez, J, Goday Arno, A, Gomez Huelgas, R, Gonzalez Juanatey, J, Hernandez Mijares, A, Jimenez Diaz, V, Jodar Gimeno, E, Lucas Morante, T, Marazuela, M, Martell Claros, N, Mauricio Puente, D, Mena Ribas, E, Merino Torres, J, Mezquita Raya, P, Nubiola Calonge, A, Ordonez Sanchez, X, Pascual Izuel, J, Perea Castilla, V, Perez Perez, A, Perez Soto, I, Quesada Charneco, M, Quesada Simon, A, Redon Mas, J, Rego Iraeta, A, Rodriguez Alvarez, M, Rodriguez Rodriguez, I, Saban Ruiz, J, Soto Gonzalez, A, Tinahones Madueno, F, Trescoli Serrano, C, Ulied Arminana, A, Bachus, E, Berndtsson Blom, K, Eliasson, K, Koskinen, P, Larnefeldt, H, Lif-Tiberg, C, Linderfalk, C, Lund, G, Lundman, P, Moris, L, Olsson, A, Salmonsson, S, Sanmartin Berglund, J, Sjoberg, F, Soderberg, S, Torstensson, I, Chen, J, Tien, K, Tseng, S, Tu, S, Wang, C, Wang, J, Phrommintikul, A, Yamwong, S, Jintapakorn, W, Hutayanon, P, Sansanayudh, N, Bazhan, L, Fushtey, I, Grachova, M, Katerenchuk, V, Korpachev, V, Kravchun, N, Larin, O, Mykhalchyshyn, G, Myshanych, H, Oleksyk, O, Orlenko, V, Pashkovska, N, Pertseva, N, Petrosyan, O, Smirnov, I, Vlasenko, M, Zlova, T, Aye, M, Baksi, A, Balasubramani, M, Beboso, R, Blagden, M, Bundy, C, Cookson, T, Copland, A, Emslie-Smith, A, Green, F, Gunstone, A, Issa, B, Jackson-Voyzey, E, Johnson, A, Maclean, M, Mcknight, J, Muzulu, S, O'Connell, I, Oyesile, B, Patterson, C, Pearson, E, Philip, S, Smith, P, Sukumaran, U, Abbas, J, Aggarwala, G, Akhter, F, Andersen, J, Anglade, M, Argoud, G, Ariani, M, Ashdji, R, Bakhtari, L, Banerjee, S, Bartlett, A, Baum, H, Bays, H, Beasley, R, Belfort de Aguiar, R, Benjamin, S, Bhagwat, R, Bhargava, A, Bode, B, Bratcher, C, Briskin, T, Brockmyre, A, Broughton, R, Brown, J, Budhraja, M, Cannon, K, Carr, J, Cathcart, H, Cavale, A, Chaykin, L, Cheung, D, Childress, R, Cohen, A, Condit, J, Cooksey, E, Cornett, G, Dauber, I, Davila, W, De Armas, L, Dean, J, Detweiler, R, Diaz, E, Di Giovanna, M, Dor, I, Drummond, W, Eagerton, D, Earl, J, Eaton, C, Ellison, H, Farris, N, Fiel, T, Firek, A, First, B, Forgosh, L, French, W, Gandy, W, Garcia, R, Gill, S, Gordon, M, Guice, M, Gummadi, S, Hackenyos, J, Hairston, K, Hanson, L, Harrison, L, Hartman, I, Heitner, J, Hejeebu, S, Hermany, P, Hernandez-Cassis, C, Hidalgo, H, Higgins, A, Ibrahim, H, Jacobs, S, Johnson, D, Joshi, P, Kaster, S, Kellum, D, Kim, E, Kirby, W, Knouse, A, Kulback, S, Kumar, M, Kuruvanka, T, Labroo, A, Lasswell, W, Lentz, J, Lenzmeier, T, Lewis, D, Li, Z, Lillestol, M, Little, R, Lorraine, R, McKeown-Biagas, C, Mcneill, R, Mehta, A, Miller, A, Moran, J, Morawski, E, Nadar, V, O'Connor, T, Odio, A, Parker, R, Patel, R, Phillips, L, Raad, G, Rahman, A, Raikhel, M, Raisinghani, A, Rajan, R, Rasouli, N, Rauzi, F, Rohr, K, Roseman, H, Rovner, S, Saba, F, Sachson, R, Schabauer, A, Schneider, R, Schuchard, T, Sensenbrenner, J, Shlesinger, Y, Singh, N, Sivalingam, K, Stonesifer, L, Storey, D, Suh, D, Tahir, M, Tan, A, Tan, M, Taylon, A, Thakkar, M, Tripathy, D, Uwaifo, G, Vedere, A, Venugopal, C, Vo, A, Welch, M, Welker, J, White, A, Willis, J, Wynne, A, Yazdani, S, Price, L, Lokhngina, Y, Xing, W, Overton, R, Stewart, M, Stead, J, Lindsay, A, Patel, V, Ross, J, Soffer, J, Daga, S, Sowell, M, Patel, P, Garvey, L, Ackert, J, Abraham, S, Sabol, M, Altobelli, D, Ha, J, Kulkarni, M, Noronha, D, Casson, E, Zang, E, Sandhu, C, Kumar, R, Chen, D, Taft, L, Ye, J, Shannon, J, Wilson, T, Babi, C, Miller, D, Russell, R, Bull, G, Hereghty, B, Fernandez-Salazar, E, Longley, T, Donaldson, J, Jarosz, M, Murphy, K, Adams, P, James, R, Richards, J, Sedani, S, Althouse, D, Watson, D, Lorimer, J, Lauder, S, Schultheis, R, Womer, T, Wraight, E, Li, W, Price-Olsen, E, Watson, A, Kelly, A, Mclaughlin, P, Fleming, J, Schubert, J, Schleiden, D, Harris, T, Prakash, R, Breneman, J, Deshpande, S, Saswadkar, A, Kumari, A, Shitut, A, Raorane, A, Karmalkar, A, Mhambrey, A, Bhosale, A, Vaphare, A, Patil, A, Khandelwal, C, Shaik, F, Nadar, M, Karka, M, Kadgaonkar, N, Gupta, N, Aher, N, Potnis, O, Naicker, P, Shinde, R, Sharma, R, Godse, R, Solanki, S, Sahu, S, Dumbre, S, Kumar, S, Patil, S, Mandal, T, Hernandez A. F., Green J. B., Janmohamed S., D'Agostino R. B., Granger C. B., Jones N. P., Leiter L. A., Rosenberg A. E., Sigmon K. N., Somerville M. C., Thorpe K. M., McMurray J. J. V., Del Prato S., Califf R. M., Holman R., DeMets D., Riddle M., Goodman S., McGuire D., Alexander K., Devore A., Melloni C., Patel C., Kong D., Bloomfield G., Roe M., Tricoci P., Harrison R., Lopes R., Mathews R., Mehta R., Schuyler Jones W., Vemulapalli S., Povsic T., Eapen Z., Dombrowski K., Kolls B., Jordan D., Ambrosy A., Greene S., Mandawat A., Shavadia J., Cooper L., Sharma A., Guimaraes P., Friedman D., Wilson M., Endsley P., Gentry T., Collier J., Perez K., James K., Roush J., Pope C., Howell C., Johnson M., Bailey M., Cole J., Akers T., Vandyne B., Thomas B., Rich J., Bartone S., Beaulieu G., Brown K., Chau T., Christian T., Coker R., Greene D., Haddock T., Jenkins W., Haque G., Marquess M., Pesarchick J., Rethaford R., Stone A., Al Kawas F., Anderson M., Enns R., Sinay I., Mathieu C., Yordanov V., Hramiak I., Haluzik M., Galatius S., Guerci B., Nauck M., Migdalis I., Tan C. B. K., Kocsis G., Giaccari A., Lee M. K., Munoz E. G. C., Cornel J., Birkeland K., Pinto M., Tirador L., Olesinska-Mader M., Shestakova M., Distiller L., Lopez-Sendon J., Eliasson B., Chiang C. -E., Srimahachota S., Mankovsky B., Bethel M. A., Dungan K., Kosiborod M., Alvarisqueta A., Baldovino J., Besada D., Calella P., Cantero M. C., Castano P., Chertkoff A., Cuadrado J., De Loredo L., Dominguez A., Espanol M. V., Finkelstein H., Frechtel G., Fretes J., Garrido Santos N., Gonzalez J., Litvak M., Loureyro J., Maffei L., Maldonado N., Mohr Gasparini D., Orio S., Perez Manghi F., Rodriguez Papini N., Sala J., Schygiel P., Sposetti G., Ulla M., Verra F., Zabalua S., Zaidman C., Crenier L., Debroye C., Duyck F., Scheen A., Van Gaal L., Vercammen C., Damyanova V., Dimitrov S., Kovacheva S., Lozanov L., Margaritov V., Mihaylova-Shumkova R., Nikolaeva A., Stoyanova Z., Akhras R., Beaudry Y., Bedard J., Berlingieri J., Chehayeb R., Cheung S., Conway J., Cusson J., Della Siega A., Dumas R., Dzongowski P., Ferguson M., Gaudet D., Grondin F., Gupta A., Gupta M., Halperin F., Houle P. -A., Jones M., Kouz S., Kovacs C., Landry D., Lonn E., O'Mahony W., Peterson S., Reich D., Rosenbloom A., St-Maurice F., Tugwell B., Vizel S., Woo V., Brychta T., Cech V., Dvorakova E., Edelsberger T., Halciakova K., Krizova J., Lastuvka J., Piperek M., Prymkova V., Raclavska L., Silhova E., Urbanek R., Vrkoc J., Andersen U., Bronnum-Schou J., Hove J., Jensen J. S., Kober L., Kristiansen O. P., Lund P., Melchior T., Nyvad O., Schou M., Boye A., Cadinot D., Gouet D., Henry P., Kessler L., Lalau J. -D., Petit C., Thuan J. -F., Voinot C., Vouillarmet J., Axthelm C., Berger D., Bieler T., Birkenfeld A., Bott J., Busch K., Caca K., Chevts J., Donaubauer T., Erlinger R., Funke K., Grosskopf J., Hagenow A., Hamann M., Hartard M., Heymer P., Huppertz W., Illies G., Jacob S., Jung T., Kahrmann G., Kast P., Kellerer M., Kempe H. -P., Khariouzov A., Klausmann G., Klein C., Kleinecke-Pohl U., Kleinertz K., Koch T., Kosch C., Lorra B., Luedemann J., Luttermann M., Maxeiner S., Milek K., Moelle A., Neumann G., Nischik R., Oehrig-Pohl E., Plassmann G., Pohlmeier L., Proepper F., Regner S., Rieker W., Rose L., Samer H., Sauter J., Schaper F., Schiffer C., Schmidt J., Scholz B. -M., Schulze J., Segner A., Seufert J., Sigal H., Steindorf J., Stockhausen J., Stuebler P., Taeschner H., Tews D., Tschoepe D., Wilhelm K., Zeller-Stefan H., Avramidis I., Bousboulas S., Bristianou M., Dimitriadis G., Elisaf M., Kotsa K., Melidonis A., Mitrakou A., Pagkalos E., Papanas N., Pappas A., Sampanis C., Tentolouris N., Tsapas A., Tzatzagou G., Ozaki R., Hajdu C., Harcsa E., Konyves L., Mucsi J., Pauker Z., Petro G., Ples Z., Revesz K., Sandor V., Vass V., Avogaro A., Boemi M., Bonadonna R., Consoli A., De Cosmo S., Di Bartolo P., Dotta F., Frontoni S., Galetta M., Gambineri A., Gazzaruso C., Giorgino F., Lauro D., Orsi E., Paolisso G., Perriello G., Piatti P., Pontiroli A., Ponzani P., Rivellese A. A., Sesti G., Tonolo G., Trevisan R., Ahn C. W., Baik S. -H., Cha B. -S., Chung C. -H., Jang H. C., Kim C. -J., Kim H. S., Kim I. J., Lee E. Y., Lee H. W., Lee K. -W., Moon K. -W., Namgung J., Park K. S., Yoo S. J., Yu J., Llamas E. -A. B., Cervantes-Escarcega J. -L., Flota-Cervera L. F., Gonzalez-Gonzalez J. G., Pascoe-Gonzalez S., Pelayo-Orozco E. S., Ramirez-Diaz S. -P., Saldana-Mendoza A., Jerjes-Diaz C. S., Torres-Colores J. J., Vidrio-Velazquez M., Villagordoa-Mesa J., Beijerbacht H. P., Groutars R. G. E. J., Hoek B. A., Hoogslag P. A. M., Kooy A., Kragten J. A., Lieverse A. G., Swart H. P., Viergever E. P., Ahlqvist J., Cooper J., Gulseth H., Guttormsen G., Wium C., Arbanil H., Calderon J., Camacho L., Espinoza A. D., Garrido E., Luna A., Manrique H., Revoredo F. M., Gonzales R. V., Rincon L. Z., Zubiate C., Ebo G., Morales-Palomares E., Arciszewska M., Banach M., Bijata-Bronisz R., Derezinski T., Gadzinski W., Gajek J., Klodawska K., Krzyzagorska E., Madej A., Miekus P., Opiela J., Romanczuk P., Siegel A., Skokowska E., Stankiewicz A., Stasinska T., Trznadel-Morawska I., Witek R., Aksentyev S., Bondar I., Demidova I., Dreval A., Ershova O., Galstyan G., Garganeeva A., Izmozherova N., Karetnikova V., Kharakhulakh M., Khokhlov A., Kobalava Z., Koshelskaya O., Kosmacheva E., Kostin V., Koziolova N., Kuzin A., Lesnov V., Lysenko T., Markov V., Mayorov A., Moiseev S., Myasoedova S., Petunina N., Rebrov A., Ruyatkina L., Samoylova J., Sazonova O., Shilkina N., Sokolova N., Vasilevskaya O., Verbovaya N., Vishneva E., Vorobyev S., Vorokhobina N., Zanozina O., Zhdanova E., Zykova T., Burgess L., Coetzee K., Dawood S., Lombard L., Makotoko E., Moodley R., Oosthuysen W., Sarvan M., Calvo Gomez C., Cano Rodriguez I., Castro Conde A., Cequier Fillat A., Cuatrecasas Cambra G., de Alvaro Moreno F., De Teresa Parreno L., Delgado Lista J., Dominguez Escribano J. R., Duran Garcia S., Elvira Gonzalez J., Fernandez Rodriguez J. M., Goday Arno A., Gomez Huelgas R., Gonzalez Juanatey J. R., Hernandez Mijares A., Jimenez Diaz V. A., Jodar Gimeno E., Lucas Morante T., Marazuela M., Martell Claros N., Mauricio Puente D., Mena Ribas E., Merino Torres J. F., Mezquita Raya P., Nubiola Calonge A., Ordonez Sanchez X., Pascual Izuel J. M., Perea Castilla V., Perez Perez A., Perez Soto I., Quesada Charneco M., Quesada Simon A., Redon Mas J., Rego Iraeta A., Rodriguez Alvarez M., Rodriguez Rodriguez I., Saban Ruiz J., Soto Gonzalez A., Tinahones Madueno F., Trescoli Serrano C., Ulied Arminana A., Bachus E., Berndtsson Blom K., Eliasson K., Koskinen P., Larnefeldt H., Lif-Tiberg C., Linderfalk C., Lund G., Lundman P., Moris L., Olsson A., Salmonsson S., Sanmartin Berglund J., Sjoberg F., Soderberg S., Torstensson I., Chen J. -F., Tien K. J., Tseng S. -T., Tu S. -T., Wang C. -Y., Wang J. -H., Phrommintikul A., Yamwong S., Jintapakorn W., Hutayanon P., Sansanayudh N., Bazhan L., Fushtey I., Grachova M., Katerenchuk V., Korpachev V., Kravchun N., Larin O., Mykhalchyshyn G., Myshanych H., Oleksyk O., Orlenko V., Pashkovska N., Pertseva N., Petrosyan O., Smirnov I., Vlasenko M., Zlova T., Aye M., Baksi A., Balasubramani M., Beboso R., Blagden M., Bundy C., Cookson T., Copland A., Emslie-Smith A., Green F., Gunstone A., Issa B., Jackson-Voyzey E., Johnson A., Maclean M., McKnight J., Muzulu S., O'Connell I., Oyesile B., Patterson C., Pearson E., Philip S., Smith P., Sukumaran U., Abbas J., Aggarwala G., Akhter F., Andersen J., Anglade M., Argoud G., Ariani M., Ashdji R., Bakhtari L., Banerjee S., Bartlett A., Baum H., Bays H., Beasley R., Belfort de Aguiar R., Benjamin S., Bhagwat R., Bhargava A., Bode B., Bratcher C., Briskin T., Brockmyre A., Broughton R., Brown J., Budhraja M., Cannon K., Carr J., Cathcart H., Cavale A., Chaykin L., Cheung D., Childress R., Cohen A., Condit J., Cooksey E., Cornett G. M., Dauber I., Davila W., De Armas L., Dean J., Detweiler R., Diaz E., Di Giovanna M., Dor I., Drummond W., Eagerton D., Earl J., Eaton C., Ellison H., Farris N., Fiel T., Firek A., First B., Forgosh L., French W., Gandy W., Garcia R., Gill S., Gordon M., Guice M., Gummadi S., Hackenyos J., Hairston K., Hanson L., Harrison L., Hartman I., Heitner J., Hejeebu S., Hermany P., Hernandez-Cassis C., Hidalgo H., Higgins A., Ibrahim H., Jacobs S., Johnson D., Joshi P., Kaster S., Kellum D., Kim C., Kim E., Kirby W., Knouse A., Kulback S., Kumar M., Kuruvanka T., Labroo A., Lasswell W., Lentz J., Lenzmeier T., Lewis D., Li Z., Lillestol M., Little R., Lorraine R., McKeown-Biagas C., McNeill R., Mehta A., Miller A., Moran J., Morawski E., Nadar V., O'Connor T., Odio A., Parker R., Patel R., Phillips L., Raad G., Rahman A., Raikhel M., Raisinghani A., Rajan R., Rasouli N., Rauzi F., Rohr K., Roseman H., Rovner S., Saba F., Sachson R., Schabauer A., Schneider R., Schuchard T., Sensenbrenner J., Shlesinger Y., Singh N., Sivalingam K., Stonesifer L., Storey D., Suh D., Tahir M., Tan A., Tan M., Taylon A., Thakkar M., Tripathy D., Uwaifo G., Vedere A., Venugopal C., Vo A., Welch M., Welker J., White A., Willis J., Wynne A., Yazdani S., Price L., Lokhngina Y., Xing W., Overton R., Stewart M., Stead J., Lindsay A., Patel V., Ross J., Soffer J., Daga S., Sowell M., Patel P., Garvey L., Ackert J., Abraham S., Sabol M. B., Altobelli D., Ha J., Kulkarni M., Noronha D., Casson E., Zang E., Sandhu C., Kumar R., Chen D., Taft L., Ye J., Shannon J., Wilson T., Babi C., Miller D., Russell R., Bull G., Hereghty B., Fernandez-Salazar E., Longley T., Donaldson J., Jarosz M., Murphy K., Adams P., James R., Richards J., Sedani S., Althouse D., Watson D., Lorimer J., Lauder S., Schultheis R., Womer T., Wraight E., Li W., Price-Olsen E., Watson A., Kelly A., McLaughlin P., Fleming J., Schubert J., Schleiden D., Harris T., Prakash R., Breneman J., Deshpande S., Saswadkar A., Kumari A., Shitut A., Raorane A., Karmalkar A., Mhambrey A., Bhosale A., Vaphare A., Patil A. P., Khandelwal C., Shaik F., Nadar M., Karka M., Kadgaonkar N., Gupta N., Aher N., Potnis O., Naicker P., Shinde R., Sharma R., Godse R., Solanki S., Sahu S., Dumbre S., Kumar S., Patil S., and Mandal T.
- Abstract
Background: Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods: We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515. Findings: Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were
- Published
- 2018
21. Re: Andrew Vickers, Sigrid V. Carlsson, Matthew Cooperberg. Routine Use of Magnetic Resonance Imaging for Early Detection of Prostate Cancer Is Not Justified by the Clinical Trial Evidence. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.04.016: Prebiopsy MRI: Through the Looking Glass
- Author
-
Bergh, R.C.N. (Roderick) van den, Rouvière, O. (Olivier), Kwast, Th.H. (Theo) van der, Briers, E. (Erik), van den Broeck, T. (Thomas), Cornford, P. (Philip), Cumberbatch, M.G. (Marcus G.), Santis, M. (Maria) de, Fanti, S. (Stefano), Fossati, N. (Nicola), Gandaglia, G. (Giorgio), Grivas, N. (Nikolaos), Grummet, J. (Jeremy), Lam, T.B. (Thomas B.), Lardas, M. (Michael), Liew, M. (Matthew), Moris, L. (Lisa), Mason, M.D. (Malcolm), Mottet, N. (Nicolas), Oprea-Lager, D.E. (Daniela E.), Ploussard, G. (Guillaume), Schoots, I.G. (Ivo), Tilki, D. (Derya), Poel, H.G. (Henk) van der, Wiegel, T. (Thomas), Willemse, P.-P.M. (Peter-Paul M.), Bergh, R.C.N. (Roderick) van den, Rouvière, O. (Olivier), Kwast, Th.H. (Theo) van der, Briers, E. (Erik), van den Broeck, T. (Thomas), Cornford, P. (Philip), Cumberbatch, M.G. (Marcus G.), Santis, M. (Maria) de, Fanti, S. (Stefano), Fossati, N. (Nicola), Gandaglia, G. (Giorgio), Grivas, N. (Nikolaos), Grummet, J. (Jeremy), Lam, T.B. (Thomas B.), Lardas, M. (Michael), Liew, M. (Matthew), Moris, L. (Lisa), Mason, M.D. (Malcolm), Mottet, N. (Nicolas), Oprea-Lager, D.E. (Daniela E.), Ploussard, G. (Guillaume), Schoots, I.G. (Ivo), Tilki, D. (Derya), Poel, H.G. (Henk) van der, Wiegel, T. (Thomas), and Willemse, P.-P.M. (Peter-Paul M.)
- Published
- 2020
- Full Text
- View/download PDF
22. PT348 - Prognostic value of biochemical recurrence following treatment with curative intent for prostate cancer: A systematic review
- Author
-
Van Den Broeck, T., Van Den Bergh, R.C.N., Arfi, N., Gross, T., Moris, L., Briers, E., Cumberbatch, M.G.K., De Santis, M., Tilki, D., Fanti, S., Fossati, N., Gillessen Sommer, S., Grummet, J., Henry, A., Lardas, M., Liew, M., Rouvière, O., Pecanka, J., Mason, M., Schoots, I.G., Van der Kwast, T., Van Der Poel, H.G., Wiegel, T., Willemse, P-P.M., Yuan, Y., Lam, T.B., Cornford, P., and Mottet, N.
- Published
- 2019
- Full Text
- View/download PDF
23. PIONEER’s operational definitions: Harmonising clinical characteristics and phenotypes data of prostate cancer patients
- Author
-
Beyer, K., primary, Moris, L., additional, Lardas, M., additional, Gandaglia, G., additional, Roobol, M., additional, Bjartell, A., additional, Omar, M.I., additional, Herrera, R., additional, Maclennan, S., additional, Smith, E., additional, Zong, J., additional, Hofmarcher, T., additional, Zounemat Kermanin, N., additional, Maclennan, S.J., additional, Briganti, A., additional, Reich, C., additional, Meulder, B., additional, and Van Hemelrijck, M., additional
- Published
- 2020
- Full Text
- View/download PDF
24. PIONEER consensus on clinician reported outcome measurements
- Author
-
Beyer, K., primary, Moris, L., additional, Gandaglia, G., additional, Lardas, M., additional, Healey, J., additional, Omar, M.I., additional, Zong, J., additional, Maclennan, S.J., additional, Briganti, A., additional, Van Hemelrijck, M., additional, and Maclennan, S., additional
- Published
- 2020
- Full Text
- View/download PDF
25. Initial steps of an online search tool development for diagnostic and prognostic factors in prostate cancer
- Author
-
Beyer, K., primary, Moris, L., additional, Lardas, M., additional, Haire, A., additional, Barletta, F., additional, Scuderi, S., additional, Molnar, M., additional, Herrera, R., additional, Rauf, A., additional, Campi, R., additional, Greco, I., additional, Shiranov, K., additional, Dabestani, S., additional, Van Den Broeck, T.B., additional, Sujenthiran, A., additional, Gacci, M., additional, Gandaglia, G., additional, Omar, M.I., additional, Maclennan, S., additional, Roobol, M., additional, Farahmand, B., additional, Vradi, E., additional, Devecsero, Z., additional, Asiimwe, A., additional, Zong, J., additional, Maclennan, S.J., additional, Collette, L., additional, N’dow, J., additional, Briganti, A., additional, Bjartell, A., additional, and Van Hemelrijck, M., additional
- Published
- 2020
- Full Text
- View/download PDF
26. The EAU biochemical recurrence risk stratification after radical prostatectomy
- Author
-
Van Den Broeck, T., primary, Van Den Bergh, R.C.N., additional, Arfi, N., additional, Gross, T., additional, Moris, L., additional, Briers, E., additional, Markus, C., additional, Maria, D.S., additional, Fanti, S., additional, Fossati, N., additional, Gillessen, S., additional, Grummet, J.P., additional, Henry, A.M., additional, Lardas, M., additional, Rouvière, O., additional, Mason, M.D., additional, Schoots, I., additional, Van Der Kwast, T., additional, Van Der Poel, H.G., additional, Wiegel, T., additional, Willemse, P.M., additional, Lam, T.B., additional, Cornford, P., additional, Mottet, N., additional, and Tilki, D., additional
- Published
- 2020
- Full Text
- View/download PDF
27. PIONEER’s systematic review of outcomes in RCTs of men with non-metastatic castration resistant prostate cancer: Is there a need for a core outcome set?
- Author
-
Beyer, K., primary, MacLennan, S., additional, Lardas, M., additional, Moris, L., additional, Vradi, E., additional, Omar, M.I., additional, MacLennan, S.J., additional, Briganti, A., additional, and Van Hemelrijck, M., additional
- Published
- 2020
- Full Text
- View/download PDF
28. Genomic analysis of localized prostate cancer identifies AZIN1 as driver of metastatic progression
- Author
-
Moris, L., primary, Van Den Broeck, T., additional, Gevaert, T., additional, Smeets, E., additional, Helsen, C., additional, Handle, F., additional, Van Poppel, H., additional, Everaerts, W., additional, Lambrechts, D., additional, Buerki, C., additional, Davicioni, E., additional, Joniau, S., additional, and Claessens, F., additional
- Published
- 2020
- Full Text
- View/download PDF
29. Current treatment options for locally advanced prostate cancer: EAU (-SIOG) guidelines view and recommendations
- Author
-
Moris, L., primary, Cumberbatch, M.C., additional, Van Den Broeck, T., additional, Gandaglia, G., additional, Fossati, N., additional, Briers, E., additional, Cornford, P., additional, De Santis, M., additional, Fanti, S., additional, Gillessen, S., additional, Grummet, J., additional, Henry, A.M., additional, Lam, T.B.L., additional, Lardas, M., additional, Liew, M., additional, Mason, M.D., additional, Rouvière, O., additional, Tilki, D., additional, Schoots, I.G., additional, Van Den Bergh, R.C.N., additional, Van Der Kwast, T.H., additional, Van Der Poel, H.G, additional, Willemse, P.M., additional, Mottet, N., additional, and Wiegel, T., additional
- Published
- 2020
- Full Text
- View/download PDF
30. The Cancer Of the Bladder Risk Assessment (COBRA) score for estimating cancer-specific survival after radical cystectomy: External validation in a large bi-institutional European cohort
- Author
-
Muilwijk, T., primary, Akand, M., additional, Soria, F., additional, Giordano, A., additional, Milenkovic, U., additional, Moris, L., additional, Demaegd, L., additional, Devos, G., additional, Roussel, E., additional, Gevaert, T., additional, Van Poppel, H., additional, Albersen, M., additional, Gontero, P., additional, and Joniau, S., additional
- Published
- 2020
- Full Text
- View/download PDF
31. EAU-EANM-ESTRO-ESUR-SIOG Prostate Cancer Guideline Panel Consensus Statements for Deferred Treatment with Curative Intent for Localised Prostate Cancer from an International Collaborative Study (DETECTIVE Study)
- Author
-
Lam, T.B., MacLennan, S., Willemse, P.M., Mason, M.D., Plass, K., Shepherd, R., Baanders, R., Bangma, Chris H., Bjartell, A., Bossi, A., Briers, E., Briganti, A., Buddingh, K.T., Catto, J.W., Colecchia, M., Cox, B.W., Cumberbatch, M.G.K., Davies, J., Davis, N.F., De Santis, M., Dell'Oglio, P., Deschamps, A., Donaldson, J.F., Egawa, S., Fankhauser, C.D., Fanti, S., Fossati, N., Gandaglia, G., Gillessen, S., Grivas, N., Gross, T., Grummet, J.P., Henry, A.M., Ingels, A., Irani, J., Lardas, M., Liew, M., Lin, D.W., Moris, L., Omar, M.I., Pang, K.H., Paterson, C.C., Renard-Penna, R., Ribal, M.J., Roobol, M.J., Roupret, M., Rouviere, O., Sancho Pardo, G., Richenberg, J., Schoots, I.G., Sedelaar, J.P.M., Stricker, P., Tilki, D., Vahr Lauridsen, S., van den Bergh, R.C.N., Van den Broeck, T., van der Kwast, T.H., van der Poel, H.G., van Leenders, G., Varma, M., Violette, P.D., Wallis, C.J.D., Wiegel, T., Wilkinson, K., Zattoni, F., N'Dow, J.M.O., Van Poppel, H., Cornford, P., Mottet, N., Lam, T.B., MacLennan, S., Willemse, P.M., Mason, M.D., Plass, K., Shepherd, R., Baanders, R., Bangma, Chris H., Bjartell, A., Bossi, A., Briers, E., Briganti, A., Buddingh, K.T., Catto, J.W., Colecchia, M., Cox, B.W., Cumberbatch, M.G.K., Davies, J., Davis, N.F., De Santis, M., Dell'Oglio, P., Deschamps, A., Donaldson, J.F., Egawa, S., Fankhauser, C.D., Fanti, S., Fossati, N., Gandaglia, G., Gillessen, S., Grivas, N., Gross, T., Grummet, J.P., Henry, A.M., Ingels, A., Irani, J., Lardas, M., Liew, M., Lin, D.W., Moris, L., Omar, M.I., Pang, K.H., Paterson, C.C., Renard-Penna, R., Ribal, M.J., Roobol, M.J., Roupret, M., Rouviere, O., Sancho Pardo, G., Richenberg, J., Schoots, I.G., Sedelaar, J.P.M., Stricker, P., Tilki, D., Vahr Lauridsen, S., van den Bergh, R.C.N., Van den Broeck, T., van der Kwast, T.H., van der Poel, H.G., van Leenders, G., Varma, M., Violette, P.D., Wallis, C.J.D., Wiegel, T., Wilkinson, K., Zattoni, F., N'Dow, J.M.O., Van Poppel, H., Cornford, P., and Mottet, N.
- Abstract
Contains fulltext : 215783.pdf (publisher's version ) (Closed access), BACKGROUND: There is uncertainty in deferred active treatment (DAT) programmes, regarding patient selection, follow-up and monitoring, reclassification, and which outcome measures should be prioritised. OBJECTIVE: To develop consensus statements for all domains of DAT. DESIGN, SETTING, AND PARTICIPANTS: A protocol-driven, three phase study was undertaken by the European Association of Urology (EAU)-European Association of Nuclear Medicine (EANM)-European Society for Radiotherapy and Oncology (ESTRO)-European Association of Urology Section of Urological Research (ESUR)-International Society of Geriatric Oncology (SIOG) Prostate Cancer Guideline Panel in conjunction with partner organisations, including the following: (1) a systematic review to describe heterogeneity across all domains; (2) a two-round Delphi survey involving a large, international panel of stakeholders, including healthcare practitioners (HCPs) and patients; and (3) a consensus group meeting attended by stakeholder group representatives. Robust methods regarding what constituted the consensus were strictly followed. RESULTS AND LIMITATIONS: A total of 109 HCPs and 16 patients completed both survey rounds. Of 129 statements in the survey, consensus was achieved in 66 (51%); the rest of the statements were discussed and voted on in the consensus meeting by 32 HCPs and three patients, where consensus was achieved in additional 27 statements (43%). Overall, 93 statements (72%) achieved consensus in the project. Some uncertainties remained regarding clinically important thresholds for disease extent on biopsy in low-risk disease, and the role of multiparametric magnetic resonance imaging in determining disease stage and aggressiveness as a criterion for inclusion and exclusion. CONCLUSIONS: Consensus statements and the findings are expected to guide and inform routine clinical practice and research, until higher levels of evidence emerge through prospective comparative studies and clinical trials. PATIENT
- Published
- 2019
32. Liraglutide and Renal Outcomes in Type 2 Diabetes
- Author
-
Mann JFE, Ørsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, Tornøe K, Zinman B, Buse JB, LEADER Steering Committee and Investigators. Bergenstal R, Daniels G, Moses AC, Nauck M, Nissen S, Pocock S, Steinberg W, Stockner M, Kristensen P, Ravn LS, Zychma M, Flyvbjerg A, Ford I, Kloos RT, Schactman MJ, Sleight P, Swedberg K, Tenner SM, Akalın S, Arechavaleta R, Bain S, Babkowski MC, Benroubi M, Berard L, Comlekci A, Czupryniak L, Eliasson B, Eriksson M, Fonseca V, Franek E, Gross J, Hafidh K, Haluzik M, Hayes F, Huang YY, Jacob S, Kaddaha G, Khalil A, Kilhovd B, Laakso M, Leiter L, Lalic N, Ji L, Luedemann J, Mannucci E, Marre M, Masmiquel L, Mota M, Omar M, O’Shea D, Pan C, Petrie J, Pieber T, Pratley R, Raz I, Rea R, Rutten G, Satman I, Shestakova M, Simpson R, Smith D, Tack C, Tarnow L, Thomas N, Van Gaal L, Travert F, Vidal J, Warren M, Yoon KH, Tuttle RM, Sheerman SI, Hegedüs L, Baerwald H, Bergenstal M, Celik S, Dias C, Eder M, Fitzgibbons S, Irvhage L, Kloluckova J, Kriulianski R, McDuffie R, Moen S, Paster A, Saalfeld RM, Sankar K, Shehaj E, Swierzewska P, Tiktin M, Tovey S, Gibson CM, Chakrabarti AK, Dashe JF, Hinchey J, Leary MC, Pride Y, Wiviott S, Allen S, Mehr AP, Mutter WP, Parikh S, Ray S, Cheifetz A, Leffler D, Sheth S, Alexander E, Gaglia JL, Goessling W, Mitzner LD, Rosenberg C, Snow KJ, Wagner A, Piazza G, Abell S, Davis T, D'Emden M, Ding SA, Gilfillan C, Greenaway T, Gunawan F, Ho J, Jackson R, Kalra B, Lau SL, Lin J, MacIsaac R, Makepeace A, Malabu U, Marjason J, McCallum R, McLean M, Moin N, Petersons C, Price S, Roberts A, Roberts D, Sangla K, Stranks S, Tan Y, Thynne T, Walters J, Ward G, Wen W, Zhang J, Brix J, Feder A, Höbaus C, Höllerl F, Höller V, Kotter T, Kratz E, Krzizek EC, Leb-Stoeger U, Mader J, Mras N, Novak E, Obendorf F, Peric S, Pesau G, Prager R, Ribitsch A, Schnack C, Schernthaner G, Wascher T, Batens AH, Benhalima K, De Block C, Ernest P, Fouckova A, Jandrain B, Lapauw B, Letiexhe M, Mathieu C, Neven S, Peiffer F, Ruige J, Scheen A, Taes Y, Van Boxelaer I, Vandistel G, Van Durme Y, Verhaegen A, Alencar E, Alencar R, Almeida AC, Alves B, Alves E, Alves G, Alves J, Araujo L, Arruda V, Augusto GA, Baggentoss R, Balestrassi L, Barbosa M, Barcelos I, Belem L, de Bem A, Betti RT, Bona R, Bosco A, Branda J, Bronstein M, Bueno T, Bulcão T, Caiado F, Camazzola F, Cambréa MF, Campos S, Canani L, Carra MK, Caruso S, Carvalho N, Casillo A, Castro D, Cavalcanti T, Cavichioli V, Cercato C, Chacra A, Challela W, Charchar HS, Chaves C, Chrisman C, Correia-Deur J, da Costa A Jr, Costa M, Costi B, Coutinho P, Coutinho W, Cunha MR, Daher J Jr, Davini E, Democh D Jr, Eliaschewitz F, Esmanhoto Facin G, Farias F, Felício J, Fernandes V, Filho CS, Filho FF, Filho M, Fontan D, Fontenele AP, Forti A, Franco D, Freire K, Fusaro A, Genestreti P, Gerchman F, Godi A, Gomes KF, Gonçalves P, Gonçalves R, Griz L, Grossman M, Gurgel MH, Vasconcellos Haddad AW, Halpern A, Hissa M, Inuy A, Jaime J, Jonasson T, Jorge JC, Malucelli FJ, Kohara S, Kramer C, Lacerda C, Ladeira S, Lana J, Lastebasse F, Leitão A, Leite S, Lerário AC, Lima D, Lima M, Lippi V, Lunardi M, Machado E, Maia F, Maia J, Maia KP, Mañas N, Marchisotti F, Marinho C, Martins C, Figueiredo de Medeiros F, Melo A, Melo F, Mendonca E, Mendonça P, Filho RM, Miguel M, Miléo K, Miyahara M, Montenegro AP, Moraes A, Moreira A, Ítalo Mota J, Mothe FS, Murro A, Nakatani V, Napoli TF, Neto BG, Neto OQ, Niclewicz E, Ohe LN, Oliveira F, Oliveira M, Panarotto D, Parente E, Parolin S, Pechmann L, Costa da Penha P, Perlamagna L, Perotta B, Pimentel L, Pinto M, Poço C, Ponte C, Prazeres P, Quintao E, Raduan R, Rassi DT, Rassi N, Reck L, Montenegro R Jr, Ribeiro R, Rodovalho S, Silveira Rodrigues G, Rollin G, Rossi S, Sabino C, Sales AP, Salles J, Sampaio CR, Santana L, Sato V, da Silva Santos M, Santos NL, Santos R, Saraiva J, Sartori C, Sena R, Sevilha M, Sgarbi J, Silva D, D'albuquerque Silva L, Silva ME, Siqueira K, Soares S, Sobreira W, Sousa B, Souza AC, Souza B, Tambascia M, Tarantino R, Tenor F, Tomarchio M, Triches C, Tristão LJ, Valenti A, Vasques E, Vencio S, Vianna A, Munhoz Vidotto T, Vieira S, Villar H, Visconti G, Volaco A, Wajchenberg B, Zanatta L, Zimmerman L, Abbott EC, Abu-Bakare A, Advani A, Allison R, Bishara P, Bowering CK, Cheng A, Chouinard S, Clayton D, Conway J, D'Amours M, de Tugwell B, DeYoung P, D'Ignazio G, Dube F, Ekoe JM, Fagan S, Garceau C, Gottesman I, Hanna A, Harris S, Hramiak IM, Hurd C, Imran S, Josse R, Joyce C, Kaiser S, Khan F, Kirouac I, Kovacs C, Labonte I, Langlois WJ, Levac MF, Liutkus J, McDonald C, Milosevic V, Nyomba BL, Paul T, Raby K, Ransom T, Reichert SM, Retnakaran R, Rabasa-Lhoret R, Raff E, Shaikholeslami R, Sigalas J, Yip CE, Weisnagel SJ, Woo V, Bao Y, Cai X, Chen J, Chen K, Chen M, Chen X, Chen Y, Ji Y, Lei J, Li H, Liu P, Mu Y, Ren M, Ren Y, Shi Y, Wang D, Wang F, Wang J, Wang Y, Yan L, Yang G, Yang J, Yu X, Yuan G, Xu M, Zhao X, Zheng J, Zhou L, Anderlová K, Brožová J, Haluzík M, Hanušová V, Kosák M, Křížová J, Mráz M, Owen K, Rušavý Z, Tomešová J, Trachta P, Žourek M, Andersen PH, Boesgaard T, Christensen S, Gram J, Gregersen S, Henriksen JE, Hermansen K, Jakobsen PE, Jensen J, Krogsaa A, Larsen M, Lervang HH, Madsbad S, Mortensen L, Olesen T, Pietraszek A, Ridderstråle M, Safai N, Schioldan AG, Schmidt C, Snorgaard O, Stidsen J, Cederberg H, Haapamäki H, Hukkanen J, Jauhiainen R, Kujari ML, Lahtela J, Laine M, Mäkelä J, Miilunpohja M, Savolainen M, Taurio J, Vänttinen M, Creton C, Cosma NV, Dillinger J, Jacques JL, Guedj AM, Moulla M, Petit C, Ratsianoharana V, Richter D, Rodier M, Roussel R, Hinz A, Politz E, Esser M, Deuse U, Mittag D, Hagenow A, Jacob F, Jordan R, Gantke D, Venschott-Jordan U, Löhr C, Klausmann G, Eschenbrücher K, Karakas M, Jahrsdörfer B, Kunze MR, Wöhrle J, König W, Spielhagen H, Kilimnik A, Lüdemann HP, Lüdemann J, Mölle A, Mölle M, Müller J, Appelt S, Sauter A, Sauter J, Hartmann U, Löw A, Krötz F, Sohn HY, von Schacky C, Klauss V, Braun D, Segner A, Degtyareva E, Kreutzmann K, Paschmionka R, Hauck N, Sihal O, Busch AK, Maus O, Stübler P, Füllgraf-Horst S, Vietzke A, Müller C, Tosch-Sisting R, Lengsfeld B, Thaler J, Schaum T, Steindorf J, Steindorf S, König A, Reitschuster S, Schlott D, Clever HU, Witzel P, Kempe HP, Stemler L, Benis A, Diakoumopoulou E, Kazakos K, Kypraios N, Liatis S, Pagkalos E, Siami E, Tentolouris N, Alur VC, Agrawal M, Ali M, Asirvatham A, Asirvatham E, Bandgar TR, Balaji M, Bardoloi N, Baruah M, Bekur R, Bhansali A, Bhatia S, Bhonsley S, Bhuyan S, Borah B, Bright N, Ambrish C, Chaudhury T, Choudhury S, Chellan G, Das M, Dharmalingam M, Dutta P, Erugu A, Vinutha FP, Gunasekaran P, Das Gupta R, Iqbal A, Jagadish P, Jain S, Jebasingh H, John A, John M, Kalra S, Kasaragod P, Kesavadev J, Kumar H, Kumar P, Lakshmanan V, Lila AR, Mathew T, Miyen H, Mohan T, Motha A, Murthy C, Shivashankara N, Nanaiah A, Ommen T, Pani K, Pandey K, Paramesh S, Paramesh V, Pillai B, Prabhu M, Kalki RC, Ramachandran S, Ramu M, Rao Y, Reddy S, Saikia P, Saravu K, Selvam K, Sethi B, Shankar A, Sharma A, Shah N, Shankar P, Shetty R, Shivane V, Srivalli S, Thaseen S, Sarada S, Shirisha A, Subramani M, Balaji V, Mohan V, Padmanaban V, Verma M, Vidyasagar S, Walinjkar V, Walia R, Davenport C, Forde H, Gadintshware G, Gan KJ, Khattak A, O'Connell J, O'Shea D, Beilin V, Cahn A, Cohen O, Cukierman-Yaffe T, Daoud D, Darawsha M, Dicker D, Gavish A, Hochberg I, Ilany J, Inbal U, Itzhak B, Karasik A, Karnieli E, Khader N, Khamaisi M, Lender D, Lieberman GS, Mahamid R, Marcoviciu D, Michael L, Minuchin O, Mosenzon O, Narevichius F, Percik R, Potekhin M, Sabbah M, Sawaed S, Schurr D, Segal E, Slezak L, Vollach I, Zaina A, Zloczower M, Zolotov S, Antenore A, Arnone M, Arturi F, Barbaro V, Barone M, Di Biagio R, Buscemi C, Buscemi S, Buzzetti R, Di Carlo A, Carlone A, Caruso V, Casadidio I, Cerrelli F, Ciavarella A, Cipolloni L, Colella A, Colotto M, Consoli A, Crippa VG, Cuccuru I, Cufone S, Desideri C, Fallarino M, Febo F, Filetti S, Foffi C, Formoso G, Frosio L, Di Fulvio P, Gambineri A, Ginestra F, Grimaldi MS, Lamanna C, Leto G, Lucotti P, Lugarà M, Lumera G, Magistro A, Maranghi M, Martelli D, Mattina A, Monti LD, Parise M, Pedace E, Perticone F, Piatti P, Pompea Antonia Baldassarre M, Ragghianti B, Repaci A, Ribichini D, Da Ros S, Rossi M, Santilli M, Sesti G, Setola E, Succurro E, Sussolano E, Tarquini G, Verga S, Vitale V, Alanis RR, del Rosario Arechavaleta-Granell M, de Jesús Beltran Jaramillo T, de Jesús Rodríguez Berrones DA, Rodríguez Briones I, Rodríguez Briones R, Acevedo Castañeda ES, Chapa Grimaldo JB, Flores-Moreno CA, Garza Felix S, Nieto Flores J, Morales Franco G, Garza Morán RA, Hernández González SO, González-Gálvez G, González González JG, Hernández Salazar E, García Hernández PA, Campos Hurtado S, López-Velázco ML, Cardona Muñóz EG, Nuñez Márquez R, Campos Moreno OV, Cavazos Oliveros FJ, Haro Ortiz JA, Pelayo-Orozco ES, Sida Perez P, Vazquez Ramírez R, Uribe Rios MA, López Rodríguez JC, Rodríguez Rosales M, Robledo Durón I, Alvarado Ruíz R, González Saldivar G, Reyes Sánchez R, Sánchez-Michel BL, Contreras Sandoval AY, Velasco Gutiérrez A, Perez Verdín AE, Ramos Zavala MG, Abbink-Zandbergen E, Ahdi M, Bugter A, van Dijk M, Eisma G, Erdtsieck R, Gerards M, Gerdes V, Haak H, Harbers V, Hoogenberg K, Huvers F, Janssen W, Kars M, Kooy A, Lafeber M, Landewé-Cleuren S, Lieverse A, Meesters E, Moerman S, van Moorsel D, Nijhuis J, Smit CJ, Thevissen K, Timmerman Thijssen DM, Willemsen A, Birkeland K, Cooper J, Gulseth H, Hjelmesæth J, Jørgensen P, Kilhovd BK, Kulseng B, Nicolaisen B, Skadberg Ø, Wium C, Antkowiak-Piatyszek K, Arciszewska M, Bajkowska-Fiedziukiewicz A, Bogdanski P, Czubek U, Cypryk K, Dabrowski J, Dabrowska M, Dziedzic S, Dziewit T, Faligowska M, Fedor-Plenkowska G, Gajos G, Galicka-Latala D, Galuszka-Bilinska A, Gladysz I, Grycewicz J, Hachula G, Janas I, Jazwinska-Tarnawska E, Jedynasty K, Jozefowska M, Kaminska A, Katra B, Kitowska-Koterla J, Klupa T, Koblik T, Konduracka E, Konieczny J, Konieczny M, Kosinski M, Kulkowski G, Kunecki M, Kurmaniak M, Lesniewski R, Lominska T, Losa B, Majkowska D, Malecki M, Mirocka J, Misztal M, Mruk K, Musialik K, Olejniczak H, Opadczuk P, Peczynska J, Plinta M, Polaszewska-Muszynska M, Przech E, Pupek-Musialik D, Ruzga Z, Scibor Z, Sidorowicz-Bialynicka A, Siegel A, Stankiewicz A, Strzelecka-Sosik A, Swierszcz T, Szulinska M, Szymkowiak K, Trybul I, Witek P, Wozniak I, Zambrzycki J, Zarzycka-Lindner G, Zuradzka-Wajda D, Zurawska-Klis M, Ahn HY, Chin SO, Choi SH, Chon S, Han KA, Jang HC, Jeong KC, Kang SM, Kim JW, Kim HS, Kim SJ, Kim SW, Kim YS, Lee EY, Lim S, Min KW, Nam JY, Oh SJ, Park SY, Rhee SY, Shin JA, Son JI, Song YD, Woo JT, Yang HK, Yoo JS, Yoon JW, Avram R, Braicu MD, Carlan L, Catrinoiu D, Ciomos D, Ciorba A, Ghise G, Girgavu S, Guja C, Mihai D, Nicodim S, Nistor L, Pintilei DR, Pintilei E, Pletea N, Pop A, Rosu M, Savu O, Serban V, Sima A, Sitterli-Natea C, Suciu G, Szabo M, Szilagyi I, Timar B, Vlad A, Vladu IM, Alfaraj A, Dubova V, Dvoryashina I, Gaysina L, Gromova S, Gudkova K, Ivanova S, Ivashkina I, Kalashnikova M, Kazankova T, Khaykina E, Khaykina O, Kiseleva T, Komissarova E, Kononenko I, Koreneva V, Koshcheeva O, Koshel L, Kozachuk D, Kufelkina T, Kunitsyna M, Likhodey N, Lysenko T, Makarova O, Malceva A, Mikhailova S, Ogorodnikova E, Pavlikova I, Pekareva E, Postoeva A, Reshedko D, Reshedko G, Reshedko L, Rogaleva A, Rogova L, Rozanov D, Runov G, Samylina I, Semikina T, Sergeeva-Kondrachenko M, Shatskaya O, Shimokhina O, Smetanina S, Startseva M, Strelkova A, Suplotova L, Suvorova L, Sych Y, Valeeva A, Valeeva F, Venjkova T, Vinokurova V, Voychik E, Yanovskaya E, Yanovskaya M, Yarkova N, Yarygina E, Yuzhakova N, Zakharova T, Zanozina O, Zenovko A, Zhuk S, Zhukova E, Aleksic S, Bulatovic A, Buric B, Cvijovic G, Jelic MA, Jojic B, Jotic A, Kendereski A, Lalic K, Lukic L, Macesic M, Petkovic MM, Micic D, Milicic T, Popovic L, Prostran M, Rajkovic N, Seferovic J, Singh S, Stojanovic R, Stosic L, Vuksanovic M, Zamaklar M, Zivkovic TB, Zoric S, Aboo N, Albertse HW, Badat A, Basson M, Bawa E, Bester F, Blignaut S, Booysen S, Bosch FJ, Burgess L, Cassimjee S, Coetzee K, Du Bois J, Engelbrecht J, Finegan K, Gibson GJ, Hansa S, Hemus A, Immink IP, Jacovides A, Joshi P, Joshi S, Kapp C, KhoeleMachobane S, Uys Knox HJ, Kok J, Komati S, Lai E, Lakha D, Lehloenyane K, Mahomed AG, Meeding R, Moodley R, Moosa N, Nel J, Nell H, Van Niekerk FJ, Pillay N, Pretorius M, Prozesky H, Ramduth S, Roos J, Sarvan M, Seeber M, Siebert M, Somasundram P, Stavrides A, Venter N, Wadvalla S, Alcolea JO, Álvarez de Arcaya Vicente A, Pérez Arroyo MB, Romero Bobillo E, Buño MM, Carreira Arias JN, Cepero García D, Masmiquel Comas L, Coves Figueras MJ, de la Cuesta Mayor C, Feria-Carot MD, Frade Fernández AM, Ferreiro Gómez M, García García C, García Delgado E, Durán García S, Gómez Gómez LA, Soto González A, Hernán García C, Ángeles Tapia Herrero M, Jodar Gimeno E, Quevedo Juanals J, López Jiménez M, Masanes F, Marco Mur ÁL, Navarro López M, Ramis JN, Palmer AG, Calle Pascual A, Romero Pérez LG, Morales Portillo C, Prieto González S, Mezquita Raya P, Reyes García R, Vera TR, Rodríguez Castro C, Rodríguez Rodríguez I, Sacanella Meseguer E, Serrano Olmedo I, Lopez Soto A, Toba Alonso F, Aliaga Verdugo A, Vidal Cortada J, Vigil Medina L, Ackefelt-Frick E, Alfredsson H, Beling E, Benedek P, Crisby M, Dorkhan M, Drescik T, Eeg-Olofsson K, Eliasson K, Fardelin P, Fredholm A, Frid A, Gerok-Andersson K, Hjelmaeus L, Hufnagl A, Jasinska E, Kowalska E, Lafolie P, Lindquist O, Lundvall M, Melander E, Nicander C, Moris L, Tengmark BO, Saphir U, Skagerberg P, Steczkó-Nilsson C, Strandell B, Tomson Y, Chen JY, Chen YC, Chiang CY, Chou CW, Ho CW, Hsiao PJ, Hsieh MC, Hsu RS, Hsu SR, Huang CH, Hung WW, Lee MY, Lee YM, Lin CW, Lin CH, Lin KD, Lin SD, Lin SF, Liou MJ, Lu WT, Shin SJ, Sia HK, Su MH, Su SL, Sun JH, Tien KJ, Tsai DH, Tsai SS, Tu ST, Wang CC, Wang SY, Yang CY, Yen FC, Acikgoz A, Akalin S, Akin S, Akinci B, Akkurt A, Akturk M, Alkis N, Altun I, Altunbas HA, Altuntas Y, Araz M, Aribas S, Arslan E, Arslan G, Arslan M, Ataoglu EH, Ayan F, Aydin K, Aydogan BI, Ayvaz G, Bahadir MA, Balci MK, Basaran MN, Baskal N, Bugra MZ, Calan M, Cavdar U, Cetin F, Cinar N, Colbay M, Dagdelen S, Damci T, Davutoglu V, Demir M, Demir T, Deyneli O, Dincer I, Dogan B, Kanipek Doker KY, Engin I, Eraydin A, Erbas T, Erdogan MF, Ersoy C, Gedik A, Gokay F, Gul OO, Guler S, Gumus T, Gunes E, Gurler MY, Hatipoglu E, Ilkova H, Iyidir OT, Kabakci G, Karadag B, Karatemiz G, Karci AC, Kartal E, Kaya EB, Keskin C, Keskin EF, Kocabas G, Kocak F, Kol AK, Korkmaz H, Kucukler FK, Mesci BA, Oguz A, Orbay E, Oz H, Ozcan ND, Ozdem S, Ozisik S, Ozkan C, Ozsan M, Ozyazar M, Parlar H, Sargin H, Sargin M, Saygili F, Selek A, Simsek Y, Sisman P, Solmaz K, Soydas C, Tatliagac S, Tamer I, Temizkan S, Tulunay C, Tuncel E, Turker F, Unluhizarci K, Unluturk U, Uygur MM, Vatansever B, Yazici D, Yavuz DG, Yener S, Yenigun M, Yilmaz M, Abbas S, Alawadi F, Aziz AA, Bashier A, Rashid F, Abraham P, Adamson K, Atkin S, Aye M, Azam M, Barnett AH, Bellary S, Dhatariya K, Eaton M, English P, Ewing J, Furlong N, Gibson M, Green D, Herring R, Hordern V, Jaap A, Javed Z, Johnson A, Konya J, Kumar S, Lindsay R, Mackie A, McGlynn S, McKenzie J, Millward A, Murthy N, Paisey R, Pearson E, Piya M, Ramell M, Robertson D, Russell-Jones D, Saravanan P, Sathyapalan T, Shakher J, Shiels H, Sivaraman S, Smith J, Srinivas-Shankar U, Stokes J, Tracey I, Vaidya B, Yee M, Yemparala P, Walker J, Wiggins P, Williams J, Wright J, Mackinnon C, Inkster J, Zeeshan J, Bejnariu C, Malipatil N, Giritharan S, Lonnen K, Kyrou I, Aamir S, Ababa M, Abreu M, Adams D, Adams P, Aden J, Aguilar D, Aguillon A, Ahmed A, Ahmed B, Ahmed I, Akhtar A, Akright B, Akright L, Albarracin C, Albert S, Ali S, Aliuddin B, Almasmary A, Al-Maweri A, Alzohaili O, Amador W, Amine M, Amini S, Anderson M, Anderson L, Anderson R, Andrews M, Angel J, Anteer W, Anthony V, Antillon A, Anzures P, Arcon-Rios S, Arkin D, Arodak B, Aronne L, Aronoff S, Arreola G, Arroyo S, Asnani S, Astudillo-Tee G, Ault S, Austin B, Avila V, Avitabile N, Awasty V, Azar M, Aziz A, Bahrami P, Baig M, Bailey K, Bailey T, Baker M, Bala NS, Balbes-Reyes I, Baldwin D, Baldwin E, Balentine T, Ballard T, Baloch K, Banarer S, Baney C, Banka A, Barber L, Barber M, Barker T, Barnes K, Barnum O, Barra J, Bartkowiak A, Baula G, Bautista A, Bayliss R, Beaman M, Beatty K, Becker J, Bedolla L, Begum G, Belejchak P, Bell A, Beltran M, Belucher C, Bensfield E, Benton J, Bergamo K, Bergman B, Berry M, Bettino K, Beyea M, Bhargava A, Bhattacharya A, Bilas A, Bischoff L, Bixler L, Bizjack S, Blank R, Blankfield R, Block L, Bloodworth J, Bloomberg K, Bloomberg R, Blustin J, Boban I, Bolden A, Boncu O, Bookless P, Brassie C, Brautigam D, Bressler P, Brewster R, Brown C, Brown D, Brown F, Bruskewitz M, Bryant D, Buchanan C, Buchanan N, Buck G, Buckley S, Bueno J, Burke D, Burton K, Buske S, Byars W, Bye R, Caldwell R, Calvin K, Camacho R, Campbell E, Cannon D, Cantrell J, Caplan J, Cardenas C, Carlton J, Carpio G, Carrol A, Cartwright L, Casanova G, Castaneda L, Castle M, Castro L, Catangay J, Chaidarun S, Chambers J, Chambliss T, Chandra L, Chang A, Chang S, Chappel J, Chappel C, Chappell T, Charles C, Chavira A, Chaykin L, Check E, Chee L, Cherry A, Chestnut A, Chiarot J, Chiniwala N, Chionh K, Choe J, Christiansen M, Chrzanowski S, Chuang E, Chuck L, Clyatt J, Cohan B, Cohen R, Comi R, Comulada-Rivera A, Conner K, Connor G, Contreras R, Cook K, Cook R, Corder C, Cornejo B Sr, Cornette L, Cortes G, Cortez L, Cox C, Cox G, Craig W, Cramer B, Cromer C, Cromer M, Cuddihy R, Culmer D, Curran H, Curran M, Dadis C, Dagogo-Jack S, Dairywala I, D'Alessio D, Damberg G, Dang A, Daniel K, Davidson M, Dean J, DeBold R, Deitz P, Del M, Delaney D, Delgado E, DeMicco M, DeMuro MA, DeSalle D, Desouza C, Devireddy K, DeVries B, Dezube M, Diab I, Diesburg-Stanwood A, Dilliard J, Dilling J, Diner J, Dishongh K, Dodis R, Doing C, Doll W, Donoho A, Donovan D, Doremus N, Dorfman S, Doshi P, Dostou J, Douglas D, Douglass S, Dowell M, Drazich E, Driver E, Du H, DuBose R III, Duclos M, Dunn K, Dunnam T, Durham N, Dye L, Eagerton D, Ebenibo S, Edeoga C, Edwards G, Ekwensi J, El Asmar I, El Sayad N, Eliopoulos C, Elkosseifi M, Elmer R, Elmore M, Elson D, ElZein L, Emmert L, Erbe L, Estes S, Estrada L, Estrada A, Eveleigh T, Everhart B, Faas F, Faircloth C, Farmer M, Fehr K, Ferguson T, Fernandes J, Ferree K, Ferrington B, Fitzhugh M, Fitzsimmons R, Flanders D, Flores M, Flores E, Flores J, Florida C, Flynn J, Folmar P, Forbes R, Ford W, Fowler M, Fraker A, Francis S, Franco-Cotto E, Fratila C, Fuentes M, Galagan R, Galloway A, Garcia M, Garcia R, Garriott M, Garza J, Gass N, Gates S, Geary M, Geiger K, Geishauser J, Giglio A, Gilbert M, Godwin S, Goetter B, Goley A, Golici L, Gomori E, Gonzales J, Gore A, Gorman T, Gosmanova A, Goswami K, Gotham A, Govoni J, Graddick S, Grant T, Greca A, Green C, Greenbaum K, Greenwald J, Grover D, Grunberger G, Guice M, Guirao D, Gunna V, Guseva N, Ha T, Hagan A, Hager S, Haggag A, Haggar M, Hamilton M, Hamlet P, Hammond J, Hansen A, Harrell W, Harris E, Harris K, Harris M, Harrison L, Hartman I, Hatch A, Hayes D, Hayes M, Heath J, Heineman R, Heinzman A, Hendrick M, Herbst R, Hermayer K, Hibbard J, Hill WD, Hilliard B, Hix M, Hoch B, Hollander P, Holmes Z, Horobetz C, Horowitz R, Hsieh P, Hsieh S, Htun W, Huang J, Huber C, Hudson T, Huizar S, Hull B, Hull J, Hummer K, Hundal R, Hunt G, Hunt V, Hutchinson P, Hwang J, Iannamorelli A, Iannuzzi L, Ingram M, Iram N, Ismail-Beigi F, Jabbour S, Jackson T, Jaen L, Jain V, Jannesari R, Januski V, Japa U, Jarvis K, Jayson L, Jensen R, Jester D, Jocko C, Johnson C, Johnson M, Johnston K, Jones D, Jones J, Jordan T, Juarez M, Kaapuraala A, Kain A, Kaiser V, Kamradt K, Karatoprakli P, Karegar M, Karounos C, Karounos D, Karunaratne H, Katalenich B, Katic K, Katz M, Kaur G, Kawa A, Keib C, Keider G, Kem D, Kennedy R, Kenney B, Kereiakes D, Ketana M, Kettinger L, Khaira A, Khan A, Khan K, Khan M, Khoo T, Khrlobyan N, Kilgore J, Kim G, Kimble S, Kinsley M, Kitchen T, Klick M, Kniffen W, Knight R, Kodzwa D, Koenig T, Komarovskiy K, Kong Y, Koontz D, Krishnasamy S, Krueger E, Kuechenmeister L, Kuehl A, Kuettel K, Kugler D, Kulow T, Kupriyanchik I, Kuruvanka T, Kushner D, Kwon E, Kwon S, Kyle M, LaBryer L, Labuda J, Lafave J, Laguerre J, Laliberte A, Lane J, Langel C, Lann D, Largay J, Latif K, Latus T, Lawrence J, Ledger G, Lee FG, Lee E, Leffert J, Leinung M, Lenhard MJ, Lentino J, Leon J, Leonard M, Letassy N, Leuck K, Levin P, Levinson D, Lewis M, Light T, Lim J, Lindamood R, Lingvay I, Lipps J, Lisa A, Livingston Y, Llamas L, Loesch R, Long T, Looby R, Lopez C, Lorenz T, Lovre D, Lu P, Lucas K, Luevano G, Luidens M, Luna B, Luttrell L, Lyons T, MacAdams M, Mack D, Mack M, Madden M, Madder R, Madireddy S, Mae L, Mahakala A, Maheshwari H, Malbari H, Maldonado N, Mallitz M, Mandviwala M, Mann K, Mardahay M, Marino J, Marney A, Marshall L, Martin A, Martin E, Martinez G, Martinez-Miss S, Marx P, Massara L, Mastoor M, Matfin G, Maturu A, Maurides P, May M, Mayfield R, Maynard B, Mazza A, McCann K, McCoy J, McCoy T, McCullen MK, McDaniel C, McDaniel AM, McDermott M, McDonald A, McMasters B, McMurray C, Medlin T, Meinel M, Mendez I, Menefee J, Meredith M, Merriweather M, Mersey J, Messino C, Meyer S, Meyers L, Michael D, Midyett C, Miklius A, Milford E, Miller B, Miller H, Milligan M, Minor A, Miranda-Palma B, Mirarchi N, Mittadodla S, Mittle J, Moffat A, Mohaupt S, Mohiuddin K, Mokshagundam S, Monaco S, Monsaert R, Montano-Pereira C, Montgomery A, Moody K, Moon M, Moore D, Moore L, Morawski E, Moreau C, Morin D, Moscoa C, Motzkin C, Mueller R, Munoz C, Munoz M, Myneni A, Naderi B, Nagireddy P, Naidu J, Naidu R, Naik S, Naimark R, Nardicchi M, Ndukwu I, Neller C, Netten-Foster L, Neumiller J, New T, Newman S, Newton T, Nguyen B, Nicol B, Nicol P, Ninivaggi L, Niswender K, Norman L, Noworatzky G, Nyenwe E, O'Brien H, O'Connell T, Oden W, Odugbesan A, Oliver M, Oliver T, Olmeda C, O'Neil C, Oremus R, Ortega T, Ortiz-Santos S, Osborn T, Padmanabhan S, Papacostea O, Park I, Parker A, Parker K, Parker R, Patel C, Patel M, Patel R, Patino M, Patterson S, Paulson K, Paz A, Pemba R, Pepe C, Perez J, Perez T, Perry D, Phillips B, Phillips J, Pickett A, Pinson M, Pitzer R, Poduri M, Poehls J, Poteat T, Powell L, Prasad S, Prevost J, Price E, Priest D, Prieto L, Purewal T, Purighalla R, Purighalla U, Quadrel M, Qureshi A, Radhamma R, Rafla E, Rajab H, Ramalingam R, Ramirez A, Ramirez J, Ramirez K, Ramirez M, Randall M, Rangaraj U, Rao V, Rasmussen P, Rasouli N, Ray A, Reed J, Rems L, Renaud K, Reno M, Resnick M, Reusch J, Reynolds L, Rhoton K, Rhudy J, Ricci C, Rice L, Richardson A, Richardson L, Rickard H, Rickels M, Riff D, Rightenour N, Risser J, Rizvi A, Robertson J, Robinson A, Robinson R, Rockwell M, Rodriguez JP, Rodriguez M, Rojas M, Rojas W, Rooker-Morris L, Root C, Rose M, Rosenberg R, Rosenstock J, Roth M, Ruby R, Sachson R, Sack P, Sadler RK, Sahai S, Salazar J, Salgam M, Samal A, Samson A, Sanagorski R, Sanchez A, Sandberg J, Sanderson M, Sandoval J, Santiago E, Sapp T, Saunders J, Schill J, Schott C, Schreiman R, Schu D, Schuh K, Schutta M, Schwartz J, Schweppe L, Scofield H, Scribner A, Seal J, Sealock J, Seaton B, Sedlak-Hanslik T, Seekins K, Segal M, Seggelke S, Semenza S, Sentman P, Serra M, Seshadri P, Sevilla E, Shah S, Shaheen K, Shanik M, Shaw J, Sheets M, Shellabarger C, Sher J, Shippey J, Shivaswamy V, Shomali M, Shore D, Shroff P, Siddiqui T, Siegwald A, Silver R, Simmons D, Simons R, Sinan A, Singh M, Sirinvaravong S, Skero J, Slover-Zipf J, Small S, Smith B, Smith K, Smith M, Sohl J, Solarz SH, Soler D, Sood A, Sora N, Souchet A, Soule J, Sparks J, Spector L, Speicher R, Spillers L, Spivey T, Springer N, Sprouse H, St John J, Stacey A, Stacey H, Stafford M, Stagner E, Staples K, Steadman E, Steed R, Steeves G, Steinberg H, Stell C, Stirman E, Straub K, Strock E, Sue M, Suris O, Sutton T, Tabbah I, Talsania M, Tang R, Tapia J, Taylor K, Taylor-Hancher R, Teator R, Tekateka M, Temple B, Temple K, Teodori M, Tharp P, Thethi T, Theuma P, Thomas S, Thottan A, Thrasher J, Thrasher L, Tiemeyer M, Tinney I, Tobin T, Toma S, Tovar M, Townsend J, Trantow C, Traylor H, Trevino M, Troy M, Trumper D, Tryggestad J, Tucker C, Turner J, Turney R, Tuten C, Tyzack J, Ullo L, Underkofler C, Unger J, Urdanetta R, Valdivia V, Valenti S, Vanderheiden A, Vanderlinde-Wood M, Varma C, Vasquez E, Vazquez M, Vickery D, Villafuerte B, Villegas C, Vivar J, Vivekananthan K, Vo G, Vukojicic K, Wachter A, Wahl D, Waitmann J, Walker D, Walsh J, Walsh K, Walton A, Wang A, Wardell K, Watkins S, Watkinson J, Watts M, Watwe V, Weaver N, Weber R, Wedick C, Weeks D, Weeks L, Weindorff K, Weinstein R, Weiss S, Wenger K, Wentworth M, Werner A, West M, Whelan S, White B, White J, Whitmire M, Whittington R, Wical J, Wigley C, Wilkins F, Will K, Williams A, Wilson LE, Wince M, Wine S, Winkle P, Winner C, Wise J, Witte M, Wittenmyer J, Wood C, Wood R, Woodruff C, Worthington B, Wynn D, Wysham C, Xavier P, Yela S, Yenoby L, Young L, Younus N, Yourell V, Zaid M, Zubair I., Mann, Jfe, Ørsted, Dd, Brown-Frandsen, K, Marso, Sp, Poulter, Nr, Rasmussen, S, Tornøe, K, Zinman, B, Buse, Jb, Bergenstal R, LEADER Steering Committee and Investigators., Daniels, G, Moses, Ac, Nauck, M, Nissen, S, Pocock, S, Steinberg, W, Stockner, M, Kristensen, P, Ravn, L, Zychma, M, Flyvbjerg, A, Ford, I, Kloos, Rt, Schactman, Mj, Sleight, P, Swedberg, K, Tenner, Sm, Akalın, S, Arechavaleta, R, Bain, S, Babkowski, Mc, Benroubi, M, Berard, L, Comlekci, A, Czupryniak, L, Eliasson, B, Eriksson, M, Fonseca, V, Franek, E, Gross, J, Hafidh, K, Haluzik, M, Hayes, F, Huang, Yy, Jacob, S, Kaddaha, G, Khalil, A, Kilhovd, B, Laakso, M, Leiter, L, Lalic, N, Ji, L, Luedemann, J, Mannucci, E, Marre, M, Masmiquel, L, Mota, M, Omar, M, O’Shea, D, Pan, C, Petrie, J, Pieber, T, Pratley, R, Raz, I, Rea, R, Rutten, G, Satman, I, Shestakova, M, Simpson, R, Smith, D, Tack, C, Tarnow, L, Thomas, N, Van Gaal, L, Travert, F, Vidal, J, Warren, M, Yoon, Kh, Tuttle, Rm, Sheerman, Si, Hegedüs, L, Baerwald, H, Bergenstal, M, Celik, S, Dias, C, Eder, M, Fitzgibbons, S, Irvhage, L, Kloluckova, J, Kriulianski, R, Mcduffie, R, Moen, S, Paster, A, Saalfeld, Rm, Sankar, K, Shehaj, E, Swierzewska, P, Tiktin, M, Tovey, S, Gibson, Cm, Chakrabarti, Ak, Dashe, Jf, Hinchey, J, Leary, Mc, Pride, Y, Wiviott, S, Allen, S, Mehr, Ap, Mutter, Wp, Parikh, S, Ray, S, Cheifetz, A, Leffler, D, Sheth, S, Alexander, E, Gaglia, Jl, Goessling, W, Mitzner, Ld, Rosenberg, C, Snow, Kj, Wagner, A, Piazza, G, Abell, S, Davis, T, D'Emden, M, Ding, Sa, Gilfillan, C, Greenaway, T, Gunawan, F, Ho, J, Jackson, R, Kalra, B, Lau, Sl, Lin, J, Macisaac, R, Makepeace, A, Malabu, U, Marjason, J, Mccallum, R, Mclean, M, Moin, N, Petersons, C, Price, S, Roberts, A, Roberts, D, Sangla, K, Stranks, S, Tan, Y, Thynne, T, Walters, J, Ward, G, Wen, W, Zhang, J, Brix, J, Feder, A, Höbaus, C, Höllerl, F, Höller, V, Kotter, T, Kratz, E, Krzizek, Ec, Leb-Stoeger, U, Mader, J, Mras, N, Novak, E, Obendorf, F, Peric, S, Pesau, G, Prager, R, Ribitsch, A, Schnack, C, Schernthaner, G, Wascher, T, Batens, Ah, Benhalima, K, De Block, C, Ernest, P, Fouckova, A, Jandrain, B, Lapauw, B, Letiexhe, M, Mathieu, C, Neven, S, Peiffer, F, Ruige, J, Scheen, A, Taes, Y, Van Boxelaer, I, Vandistel, G, Van Durme, Y, Verhaegen, A, Alencar, E, Alencar, R, Almeida, Ac, B, Alve, Alves, E, Alves, G, Alves, J, Araujo, L, Arruda, V, Augusto, Ga, Baggentoss, R, Balestrassi, L, Barbosa, M, Barcelos, I, Belem, L, de Bem, A, Betti, Rt, Bona, R, Bosco, A, Branda, J, Bronstein, M, Bueno, T, Bulcão, T, Caiado, F, Camazzola, F, Cambréa, Mf, Campos, S, Canani, L, Carra, Mk, Caruso, S, Carvalho, N, Casillo, A, Castro, D, Cavalcanti, T, Cavichioli, V, Cercato, C, Chacra, A, Challela, W, Charchar, H, C, Chave, Chrisman, C, Correia-Deur, J, da Costa, A Jr, Costa, M, Costi, B, Coutinho, P, Coutinho, W, Cunha, Mr, Daher, J Jr, Davini, E, Democh, D Jr, Eliaschewitz, F, Esmanhoto Facin, G, Farias, F, Felício, J, Fernandes, V, Filho, C, Filho, Ff, Filho, M, Fontan, D, Fontenele, Ap, Forti, A, Franco, D, Freire, K, Fusaro, A, Genestreti, P, Gerchman, F, Godi, A, Gomes, Kf, Gonçalves, P, R, Gonçalve, Griz, L, Grossman, M, Gurgel, Mh, Vasconcellos Haddad AW, Halpern, A, Hissa, M, Inuy, A, J, Jaime, Jonasson, T, Jorge, Jc, Malucelli, Fj, Kohara, S, Kramer, C, Lacerda, C, Ladeira, S, Lana, J, Lastebasse, F, Leitão, A, Leite, S, Lerário, Ac, Lima, D, Lima, M, Lippi, V, Lunardi, M, Machado, E, Maia, F, Maia, J, Maia, Kp, Mañas, N, Marchisotti, F, Marinho, C, C, Martin, Figueiredo de Medeiros, F, Melo, A, Melo, F, Mendonca, E, Mendonça, P, Filho, Rm, Miguel, M, Miléo, K, Miyahara, M, Montenegro, Ap, Moraes, A, Moreira, A, Ítalo Mota, J, Mothe, F, Murro, A, Nakatani, V, Napoli, Tf, Neto, Bg, Neto, Oq, Niclewicz, E, Ohe, Ln, Oliveira, F, Oliveira, M, Panarotto, D, Parente, E, Parolin, S, Pechmann, L, Costa da Penha, P, Perlamagna, L, Perotta, B, Pimentel, L, Pinto, M, Poço, C, Ponte, C, Prazeres, P, Quintao, E, Raduan, R, Rassi, Dt, Rassi, N, Reck, L, Montenegro, R Jr, Ribeiro, R, Rodovalho, S, Silveira Rodrigues, G, Rollin, G, Rossi, S, Sabino, C, Sales, Ap, Salles, J, Sampaio, Cr, Santana, L, Sato, V, da Silva Santos, M, Santos, Nl, Santos, R, Saraiva, J, Sartori, C, Sena, R, Sevilha, M, Sgarbi, J, Silva, D, D'albuquerque Silva, L, Silva, Me, Siqueira, K, Soares, S, Sobreira, W, Sousa, B, Souza, Ac, Souza, B, Tambascia, M, Tarantino, R, Tenor, F, Tomarchio, M, Triches, C, Tristão, Lj, Valenti, A, Vasques, E, Vencio, S, Vianna, A, Munhoz Vidotto, T, Vieira, S, Villar, H, Visconti, G, Volaco, A, Wajchenberg, B, Zanatta, L, Zimmerman, L, Abbott, Ec, Abu-Bakare, A, Advani, A, Allison, R, Bishara, P, Bowering, Ck, Cheng, A, Chouinard, S, Clayton, D, Conway, J, D'Amours, M, de Tugwell, B, Deyoung, P, D'Ignazio, G, Dube, F, Ekoe, Jm, Fagan, S, Garceau, C, Gottesman, I, Hanna, A, Harris, S, Hramiak, Im, Hurd, C, Imran, S, Josse, R, Joyce, C, Kaiser, S, Khan, F, I, Kirouac, Kovacs, C, Labonte, I, Langlois, Wj, Levac, Mf, Liutkus, J, Mcdonald, C, Milosevic, V, Nyomba, Bl, Paul, T, Raby, K, Ransom, T, Reichert, Sm, Retnakaran, R, Rabasa-Lhoret, R, Raff, E, Shaikholeslami, R, Sigalas, J, Yip, Ce, Weisnagel, Sj, Woo, V, Bao, Y, Cai, X, Chen, J, Chen, K, Chen, M, Chen, X, Chen, Y, Ji, Y, Lei, J, Li, H, Liu, P, Mu, Y, Ren, M, Ren, Y, Shi, Y, Wang, D, Wang, F, Wang, J, Wang, Y, Yan, L, Yang, G, Yang, J, Yu, X, Yuan, G, Xu, M, Zhao, X, Zheng, J, Zhou, L, Anderlová, K, Brožová, J, Haluzík, M, Hanušová, V, Kosák, M, Křížová, J, Mráz, M, Owen, K, Rušavý, Z, Tomešová, J, Trachta, P, Žourek, M, Andersen, Ph, Boesgaard, T, Christensen, S, Gram, J, Gregersen, S, Henriksen, Je, Hermansen, K, Jakobsen, Pe, Jensen, J, Krogsaa, A, Larsen, M, Lervang, Hh, Madsbad, S, Mortensen, L, Olesen, T, Pietraszek, A, Ridderstråle, M, Safai, N, Schioldan, Ag, Schmidt, C, Snorgaard, O, Stidsen, J, Cederberg, H, Haapamäki, H, Hukkanen, J, Jauhiainen, R, Kujari, Ml, Lahtela, J, Laine, M, Mäkelä, J, Miilunpohja, M, Savolainen, M, Taurio, J, Vänttinen, M, Creton, C, Cosma, Nv, Dillinger, J, Jacques, Jl, Guedj, Am, Moulla, M, Petit, C, Ratsianoharana, V, Richter, D, Rodier, M, Roussel, R, Hinz, A, Politz, E, Esser, M, Deuse, U, Mittag, D, Hagenow, A, Jacob, F, Jordan, R, Gantke, D, Venschott-Jordan, U, Löhr, C, Klausmann, G, Eschenbrücher, K, Karakas, M, Jahrsdörfer, B, Kunze, Mr, Wöhrle, J, König, W, Spielhagen, H, Kilimnik, A, Lüdemann, Hp, Lüdemann, J, Mölle, A, Mölle, M, Müller, J, Appelt, S, Sauter, A, Sauter, J, Hartmann, U, Löw, A, Krötz, F, Sohn, Hy, von Schacky, C, Klauss, V, Braun, D, Segner, A, Degtyareva, E, Kreutzmann, K, Paschmionka, R, Hauck, N, Sihal, O, Busch, Ak, Maus, O, Stübler, P, Füllgraf-Horst, S, Vietzke, A, Müller, C, Tosch-Sisting, R, Lengsfeld, B, Thaler, J, Schaum, T, Steindorf, J, Steindorf, S, König, A, Reitschuster, S, Schlott, D, Clever, Hu, Witzel, P, Kempe, Hp, Stemler, L, Benis, A, Diakoumopoulou, E, Kazakos, K, Kypraios, N, Liatis, S, Pagkalos, E, Siami, E, Tentolouris, N, Alur, Vc, Agrawal, M, Ali, M, Asirvatham, A, Asirvatham, E, Bandgar, Tr, Balaji, M, Bardoloi, N, Baruah, M, Bekur, R, Bhansali, A, Bhatia, S, Bhonsley, S, Bhuyan, S, Borah, B, Bright, N, Ambrish, C, Chaudhury, T, Choudhury, S, Chellan, G, M, Da, Dharmalingam, M, Dutta, P, Erugu, A, Vinutha, Fp, Gunasekaran, P, Das Gupta, R, Iqbal, A, Jagadish, P, Jain, S, Jebasingh, H, John, A, John, M, Kalra, S, Kasaragod, P, Kesavadev, J, Kumar, H, Kumar, P, Lakshmanan, V, Lila, Ar, Mathew, T, Miyen, H, Mohan, T, Motha, A, Murthy, C, Shivashankara, N, Nanaiah, A, Ommen, T, Pani, K, Pandey, K, Paramesh, S, Paramesh, V, Pillai, B, Prabhu, M, Kalki, Rc, Ramachandran, S, Ramu, M, Rao, Y, Reddy, S, Saikia, P, Saravu, K, Selvam, K, Sethi, B, Shankar, A, Sharma, A, Shah, N, Shankar, P, Shetty, R, Shivane, V, Srivalli, S, Thaseen, S, Sarada, S, Shirisha, A, Subramani, M, Balaji, V, Mohan, V, Padmanaban, V, Verma, M, Vidyasagar, S, Walinjkar, V, Walia, R, Davenport, C, Forde, H, Gadintshware, G, Gan, Kj, Khattak, A, O'Connell, J, O'Shea, D, Beilin, V, Cahn, A, Cohen, O, Cukierman-Yaffe, T, Daoud, D, Darawsha, M, Dicker, D, Gavish, A, Hochberg, I, Ilany, J, Inbal, U, Itzhak, B, Karasik, A, Karnieli, E, Khader, N, Khamaisi, M, Lender, D, Lieberman, G, Mahamid, R, Marcoviciu, D, Michael, L, Minuchin, O, Mosenzon, O, Narevichius, F, Percik, R, Potekhin, M, Sabbah, M, Sawaed, S, Schurr, D, Segal, E, Slezak, L, Vollach, I, Zaina, A, Zloczower, M, Zolotov, S, Antenore, A, Arnone, M, Arturi, F, Barbaro, V, Barone, M, Di Biagio, R, Buscemi, C, Buscemi, S, Buzzetti, R, Di Carlo, A, Carlone, A, Caruso, V, Casadidio, I, Cerrelli, F, Ciavarella, A, Cipolloni, L, Colella, A, Colotto, M, Consoli, A, Crippa, Vg, Cuccuru, I, Cufone, S, Desideri, C, Fallarino, M, Febo, F, Filetti, S, Foffi, C, Formoso, G, Frosio, L, Di Fulvio, P, Gambineri, A, Ginestra, F, Grimaldi, M, Lamanna, C, Leto, G, Lucotti, P, Lugarà, M, Lumera, G, Magistro, A, Maranghi, M, Martelli, D, Mattina, A, Monti, Ld, Parise, M, Pedace, E, Perticone, F, Piatti, P, Pompea Antonia Baldassarre, M, Ragghianti, B, Repaci, A, Ribichini, D, Da Ros, S, Rossi, M, Santilli, M, Sesti, G, Setola, E, Succurro, E, Sussolano, E, Tarquini, G, Verga, S, Vitale, V, Alanis, Rr, del Rosario Arechavaleta-Granell, M, de Jesús Beltran Jaramillo, T, de Jesús Rodríguez Berrones DA, Rodríguez Briones, I, Rodríguez Briones, R, Acevedo Castañeda ES, Chapa Grimaldo JB, Flores-Moreno, Ca, Garza Felix, S, Nieto Flores, J, Morales Franco, G, Garza Morán RA, Hernández González SO, González-Gálvez, G, González González JG, Hernández Salazar, E, García Hernández PA, Campos Hurtado, S, López-Velázco, Ml, Cardona Muñóz EG, Nuñez Márquez, R, Campos Moreno OV, Cavazos Oliveros FJ, Haro Ortiz JA, Pelayo-Orozco, E, Sida Perez, P, Vazquez Ramírez, R, Uribe Rios MA, López Rodríguez JC, Rodríguez Rosales, M, Robledo Durón, I, Alvarado Ruíz, R, González Saldivar, G, Reyes Sánchez, R, Sánchez-Michel, Bl, Contreras Sandoval AY, Velasco Gutiérrez, A, Perez Verdín AE, Ramos Zavala MG, Abbink-Zandbergen, E, Ahdi, M, Bugter, A, van Dijk, M, Eisma, G, Erdtsieck, R, Gerards, M, Gerdes, V, Haak, H, Harbers, V, Hoogenberg, K, Huvers, F, Janssen, W, Kars, M, Kooy, A, Lafeber, M, Landewé-Cleuren, S, Lieverse, A, Meesters, E, Moerman, S, van Moorsel, D, Nijhuis, J, Smit, Cj, Thevissen, K, Timmerman Thijssen DM, Willemsen, A, Birkeland, K, Cooper, J, Gulseth, H, Hjelmesæth, J, Jørgensen, P, Kilhovd, Bk, Kulseng, B, Nicolaisen, B, Skadberg, Ø, Wium, C, Antkowiak-Piatyszek, K, Arciszewska, M, Bajkowska-Fiedziukiewicz, A, Bogdanski, P, Czubek, U, Cypryk, K, Dabrowski, J, Dabrowska, M, Dziedzic, S, Dziewit, T, Faligowska, M, Fedor-Plenkowska, G, Gajos, G, Galicka-Latala, D, Galuszka-Bilinska, A, Gladysz, I, Grycewicz, J, Hachula, G, Janas, I, Jazwinska-Tarnawska, E, Jedynasty, K, Jozefowska, M, Kaminska, A, Katra, B, Kitowska-Koterla, J, Klupa, T, Koblik, T, Konduracka, E, Konieczny, J, Konieczny, M, Kosinski, M, Kulkowski, G, Kunecki, M, Kurmaniak, M, Lesniewski, R, Lominska, T, Losa, B, Majkowska, D, Malecki, M, Mirocka, J, Misztal, M, Mruk, K, Musialik, K, Olejniczak, H, Opadczuk, P, Peczynska, J, Plinta, M, Polaszewska-Muszynska, M, Przech, E, Pupek-Musialik, D, Ruzga, Z, Scibor, Z, Sidorowicz-Bialynicka, A, Siegel, A, Stankiewicz, A, Strzelecka-Sosik, A, Swierszcz, T, Szulinska, M, Szymkowiak, K, Trybul, I, Witek, P, Wozniak, I, Zambrzycki, J, Zarzycka-Lindner, G, Zuradzka-Wajda, D, Zurawska-Klis, M, Ahn, Hy, Chin, So, Choi, Sh, Chon, S, Han, Ka, Jang, Hc, Jeong, Kc, Kang, Sm, Kim, Jw, Kim, H, Kim, Sj, Kim, Sw, Kim, Y, Lee, Ey, Lim, S, Min, Kw, Nam, Jy, Oh, Sj, Park, Sy, Rhee, Sy, Shin, Ja, Son, Ji, Song, Yd, Woo, Jt, Yang, Hk, Yoo, J, Yoon, Jw, Avram, R, Braicu, Md, Carlan, L, Catrinoiu, D, Ciomos, D, Ciorba, A, Ghise, G, Girgavu, S, Guja, C, Mihai, D, Nicodim, S, Nistor, L, Pintilei, Dr, Pintilei, E, Pletea, N, Pop, A, Rosu, M, Savu, O, Serban, V, Sima, A, Sitterli-Natea, C, Suciu, G, Szabo, M, Szilagyi, I, Timar, B, Vlad, A, Vladu, Im, Alfaraj, A, Dubova, V, Dvoryashina, I, Gaysina, L, Gromova, S, Gudkova, K, Ivanova, S, Ivashkina, I, Kalashnikova, M, Kazankova, T, Khaykina, E, Khaykina, O, Kiseleva, T, Komissarova, E, Kononenko, I, Koreneva, V, Koshcheeva, O, Koshel, L, Kozachuk, D, Kufelkina, T, Kunitsyna, M, Likhodey, N, Lysenko, T, Makarova, O, Malceva, A, Mikhailova, S, Ogorodnikova, E, Pavlikova, I, Pekareva, E, Postoeva, A, Reshedko, D, Reshedko, G, Reshedko, L, Rogaleva, A, Rogova, L, Rozanov, D, Runov, G, Samylina, I, Semikina, T, Sergeeva-Kondrachenko, M, Shatskaya, O, Shimokhina, O, Smetanina, S, Startseva, M, Strelkova, A, Suplotova, L, Suvorova, L, Sych, Y, Valeeva, A, Valeeva, F, Venjkova, T, Vinokurova, V, Voychik, E, Yanovskaya, E, Yanovskaya, M, Yarkova, N, Yarygina, E, Yuzhakova, N, Zakharova, T, Zanozina, O, Zenovko, A, Zhuk, S, Zhukova, E, Aleksic, S, Bulatovic, A, Buric, B, Cvijovic, G, Jelic, Ma, Jojic, B, Jotic, A, Kendereski, A, Lalic, K, Lukic, L, Macesic, M, Petkovic, Mm, Micic, D, Milicic, T, Popovic, L, Prostran, M, Rajkovic, N, Seferovic, J, Singh, S, Stojanovic, R, Stosic, L, Vuksanovic, M, Zamaklar, M, Zivkovic, Tb, Zoric, S, Aboo, N, Albertse, Hw, Badat, A, Basson, M, Bawa, E, Bester, F, Blignaut, S, Booysen, S, Bosch, Fj, Burgess, L, Cassimjee, S, Coetzee, K, Du Bois, J, Engelbrecht, J, Finegan, K, Gibson, Gj, Hansa, S, Hemus, A, Immink, Ip, Jacovides, A, Joshi, P, Joshi, S, Kapp, C, Khoelemachobane, S, Uys Knox HJ, Kok, J, Komati, S, Lai, E, Lakha, D, Lehloenyane, K, Mahomed, Ag, Meeding, R, Moodley, R, Moosa, N, Nel, J, Nell, H, Van Niekerk FJ, Pillay, N, Pretorius, M, Prozesky, H, Ramduth, S, Roos, J, Sarvan, M, Seeber, M, Siebert, M, Somasundram, P, Stavrides, A, Venter, N, Wadvalla, S, Alcolea, Jo, Álvarez de Arcaya Vicente, A, Pérez Arroyo MB, Romero Bobillo, E, Buño, Mm, Carreira Arias JN, Cepero García, D, Masmiquel Comas, L, Coves Figueras MJ, de la Cuesta Mayor, C, Feria-Carot, Md, Frade Fernández AM, Ferreiro Gómez, M, García García, C, García Delgado, E, Durán García, S, Gómez Gómez LA, Soto González, A, Hernán García, C, Ángeles Tapia Herrero, M, Jodar Gimeno, E, Quevedo Juanals, J, López Jiménez, M, Masanes, F, Marco Mur ÁL, Navarro López, M, Ramis, Jn, Palmer, Ag, Calle Pascual, A, Romero Pérez LG, Morales Portillo, C, Prieto González, S, Mezquita Raya, P, Reyes García, R, Vera, Tr, Rodríguez Castro, C, Rodríguez Rodríguez, I, Sacanella Meseguer, E, Serrano Olmedo, I, Lopez Soto, A, Toba Alonso, F, Aliaga Verdugo, A, Vidal Cortada, J, Vigil Medina, L, Ackefelt-Frick, E, Alfredsson, H, Beling, E, Benedek, P, Crisby, M, Dorkhan, M, Drescik, T, Eeg-Olofsson, K, Eliasson, K, Fardelin, P, Fredholm, A, Frid, A, Gerok-Andersson, K, Hjelmaeus, L, Hufnagl, A, Jasinska, E, Kowalska, E, Lafolie, P, Lindquist, O, Lundvall, M, Melander, E, Nicander, C, Moris, L, Tengmark, Bo, Saphir, U, Skagerberg, P, Steczkó-Nilsson, C, Strandell, B, Tomson, Y, Chen, Jy, Chen, Yc, Chiang, Cy, Chou, Cw, Ho, Cw, Hsiao, Pj, Hsieh, Mc, Hsu, R, Hsu, Sr, Huang, Ch, Hung, Ww, Lee, My, Lee, Ym, Lin, Cw, Lin, Ch, Lin, Kd, Lin, Sd, Lin, Sf, Liou, Mj, Lu, Wt, Shin, Sj, Sia, Hk, Su, Mh, Su, Sl, Sun, Jh, Tien, Kj, Tsai, Dh, Tsai, S, Tu, St, Wang, Cc, Wang, Sy, Yang, Cy, Yen, Fc, Acikgoz, A, Akalin, S, Akin, S, Akinci, B, Akkurt, A, Akturk, M, Alkis, N, Altun, I, Altunbas, Ha, Altuntas, Y, Araz, M, Aribas, S, Arslan, E, Arslan, G, Arslan, M, Ataoglu, Eh, Ayan, F, Aydin, K, Aydogan, Bi, Ayvaz, G, Bahadir, Ma, Balci, Mk, Basaran, Mn, Baskal, N, Bugra, Mz, Calan, M, Cavdar, U, Cetin, F, Cinar, N, Colbay, M, Dagdelen, S, Damci, T, Davutoglu, V, Demir, M, Demir, T, Deyneli, O, Dincer, I, Dogan, B, Kanipek Doker KY, Engin, I, Eraydin, A, Erbas, T, Erdogan, Mf, Ersoy, C, Gedik, A, Gokay, F, Gul, Oo, Guler, S, Gumus, T, Gunes, E, Gurler, My, Hatipoglu, E, Ilkova, H, Iyidir, Ot, Kabakci, G, Karadag, B, Karatemiz, G, Karci, Ac, Kartal, E, Kaya, Eb, Keskin, C, Keskin, Ef, Kocabas, G, Kocak, F, Kol, Ak, Korkmaz, H, Kucukler, Fk, Mesci, Ba, Oguz, A, Orbay, E, Oz, H, Ozcan, Nd, Ozdem, S, Ozisik, S, Ozkan, C, Ozsan, M, Ozyazar, M, Parlar, H, Sargin, H, Sargin, M, Saygili, F, Selek, A, Simsek, Y, Sisman, P, Solmaz, K, Soydas, C, Tatliagac, S, Tamer, I, Temizkan, S, Tulunay, C, Tuncel, E, Turker, F, Unluhizarci, K, Unluturk, U, Uygur, Mm, Vatansever, B, Yazici, D, Yavuz, Dg, Yener, S, Yenigun, M, Yilmaz, M, Abbas, S, Alawadi, F, Aziz, Aa, Bashier, A, Rashid, F, Abraham, P, Adamson, K, Atkin, S, Aye, M, Azam, M, Barnett, Ah, Bellary, S, Dhatariya, K, Eaton, M, English, P, Ewing, J, Furlong, N, Gibson, M, Green, D, Herring, R, Hordern, V, Jaap, A, Javed, Z, Johnson, A, Konya, J, Kumar, S, Lindsay, R, Mackie, A, Mcglynn, S, Mckenzie, J, Millward, A, Murthy, N, Paisey, R, Pearson, E, Piya, M, Ramell, M, Robertson, D, Russell-Jones, D, Saravanan, P, Sathyapalan, T, Shakher, J, Shiels, H, Sivaraman, S, Smith, J, Srinivas-Shankar, U, Stokes, J, Tracey, I, Vaidya, B, Yee, M, Yemparala, P, Walker, J, Wiggins, P, Williams, J, Wright, J, Mackinnon, C, Inkster, J, Zeeshan, J, Bejnariu, C, Malipatil, N, Giritharan, S, Lonnen, K, Kyrou, I, Aamir, S, Ababa, M, Abreu, M, Adams, D, Adams, P, Aden, J, Aguilar, D, Aguillon, A, Ahmed, A, Ahmed, B, Ahmed, I, Akhtar, A, Akright, B, Akright, L, Albarracin, C, Albert, S, Ali, S, Aliuddin, B, Almasmary, A, Al-Maweri, A, Alzohaili, O, Amador, W, Amine, M, Amini, S, Anderson, M, Anderson, L, Anderson, R, Andrews, M, Angel, J, Anteer, W, Anthony, V, Antillon, A, Anzures, P, Arcon-Rios, S, Arkin, D, Arodak, B, Aronne, L, Aronoff, S, Arreola, G, Arroyo, S, Asnani, S, Astudillo-Tee, G, Ault, S, Austin, B, Avila, V, Avitabile, N, Awasty, V, Azar, M, Aziz, A, Bahrami, P, Baig, M, Bailey, K, Bailey, T, Baker, M, Bala, N, Balbes-Reyes, I, Baldwin, D, Baldwin, E, Balentine, T, Ballard, T, Baloch, K, Banarer, S, Baney, C, Banka, A, Barber, L, Barber, M, Barker, T, Barnes, K, Barnum, O, Barra, J, Bartkowiak, A, Baula, G, Bautista, A, Bayliss, R, Beaman, M, Beatty, K, Becker, J, Bedolla, L, Begum, G, Belejchak, P, Bell, A, Beltran, M, Belucher, C, Bensfield, E, Benton, J, Bergamo, K, Bergman, B, Berry, M, Bettino, K, Beyea, M, Bhargava, A, Bhattacharya, A, Bilas, A, Bischoff, L, Bixler, L, Bizjack, S, Blank, R, Blankfield, R, Block, L, Bloodworth, J, Bloomberg, K, Bloomberg, R, Blustin, J, Boban, I, Bolden, A, Boncu, O, Bookless, P, Brassie, C, Brautigam, D, Bressler, P, Brewster, R, Brown, C, Brown, D, Brown, F, Bruskewitz, M, Bryant, D, Buchanan, C, Buchanan, N, Buck, G, Buckley, S, Bueno, J, Burke, D, Burton, K, Buske, S, Byars, W, Bye, R, Caldwell, R, Calvin, K, Camacho, R, Campbell, E, Cannon, D, Cantrell, J, Caplan, J, Cardenas, C, Carlton, J, Carpio, G, Carrol, A, Cartwright, L, Casanova, G, Castaneda, L, Castle, M, Castro, L, Catangay, J, Chaidarun, S, Chambers, J, Chambliss, T, Chandra, L, Chang, A, Chang, S, Chappel, J, Chappel, C, Chappell, T, Charles, C, Chavira, A, Chaykin, L, Check, E, Chee, L, Cherry, A, Chestnut, A, Chiarot, J, Chiniwala, N, Chionh, K, Choe, J, Christiansen, M, Chrzanowski, S, Chuang, E, Chuck, L, Clyatt, J, Cohan, B, Cohen, R, Comi, R, Comulada-Rivera, A, Conner, K, Connor, G, Contreras, R, Cook, K, Cook, R, Corder, C, Cornejo, B Sr, Cornette, L, Cortes, G, Cortez, L, Cox, C, Cox, G, Craig, W, Cramer, B, Cromer, C, Cromer, M, Cuddihy, R, Culmer, D, Curran, H, Curran, M, Dadis, C, Dagogo-Jack, S, Dairywala, I, D'Alessio, D, Damberg, G, Dang, A, Daniel, K, Davidson, M, Dean, J, Debold, R, Deitz, P, M, Del, Delaney, D, Delgado, E, Demicco, M, Demuro, Ma, Desalle, D, Desouza, C, Devireddy, K, Devries, B, Dezube, M, Diab, I, Diesburg-Stanwood, A, Dilliard, J, Dilling, J, Diner, J, Dishongh, K, Dodis, R, Doing, C, Doll, W, Donoho, A, Donovan, D, Doremus, N, Dorfman, S, Doshi, P, Dostou, J, Douglas, D, Douglass, S, Dowell, M, Drazich, E, Driver, E, Du, H, Dubose, R III, Duclos, M, Dunn, K, Dunnam, T, Durham, N, Dye, L, Eagerton, D, Ebenibo, S, Edeoga, C, Edwards, G, Ekwensi, J, El Asmar, I, El Sayad, N, Eliopoulos, C, Elkosseifi, M, Elmer, R, Elmore, M, Elson, D, Elzein, L, Emmert, L, Erbe, L, Estes, S, Estrada, L, A, Estrada, Eveleigh, T, Everhart, B, Faas, F, Faircloth, C, Farmer, M, Fehr, K, Ferguson, T, Fernandes, J, Ferree, K, Ferrington, B, Fitzhugh, M, Fitzsimmons, R, Flanders, D, M, Flore, E, Flore, Flores, J, Florida, C, Flynn, J, Folmar, P, Forbes, R, Ford, W, Fowler, M, Fraker, A, Francis, S, Franco-Cotto, E, Fratila, C, Fuentes, M, Galagan, R, Galloway, A, Garcia, M, Garcia, R, Garriott, M, J, Garza, Gass, N, Gates, S, Geary, M, Geiger, K, Geishauser, J, Giglio, A, Gilbert, M, Godwin, S, Goetter, B, Goley, A, Golici, L, Gomori, E, Gonzales, J, Gore, A, Gorman, T, Gosmanova, A, Goswami, K, Gotham, A, Govoni, J, Graddick, S, Grant, T, Greca, A, Green, C, Greenbaum, K, Greenwald, J, Grover, D, Grunberger, G, Guice, M, Guirao, D, Gunna, V, Guseva, N, Ha, T, Hagan, A, Hager, S, Haggag, A, Haggar, M, Hamilton, M, Hamlet, P, Hammond, J, Hansen, A, Harrell, W, Harris, E, Harris, K, Harris, M, Harrison, L, Hartman, I, Hatch, A, Hayes, D, Hayes, M, Heath, J, Heineman, R, Heinzman, A, Hendrick, M, Herbst, R, Hermayer, K, Hibbard, J, Hill, Wd, Hilliard, B, Hix, M, Hoch, B, Hollander, P, Holmes, Z, Horobetz, C, Horowitz, R, Hsieh, P, Hsieh, S, Htun, W, Huang, J, Huber, C, Hudson, T, Huizar, S, Hull, B, Hull, J, Hummer, K, Hundal, R, Hunt, G, Hunt, V, Hutchinson, P, Hwang, J, Iannamorelli, A, Iannuzzi, L, Ingram, M, Iram, N, Ismail-Beigi, F, Jabbour, S, Jackson, T, Jaen, L, Jain, V, Jannesari, R, Januski, V, Japa, U, Jarvis, K, Jayson, L, Jensen, R, Jester, D, Jocko, C, Johnson, C, Johnson, M, Johnston, K, Jones, D, Jones, J, Jordan, T, Juarez, M, Kaapuraala, A, Kain, A, Kaiser, V, Kamradt, K, Karatoprakli, P, Karegar, M, Karounos, C, Karounos, D, Karunaratne, H, Katalenich, B, Katic, K, Katz, M, Kaur, G, Kawa, A, Keib, C, Keider, G, Kem, D, Kennedy, R, Kenney, B, Kereiakes, D, Ketana, M, Kettinger, L, Khaira, A, Khan, A, Khan, K, Khan, M, Khoo, T, Khrlobyan, N, Kilgore, J, Kim, G, Kimble, S, Kinsley, M, Kitchen, T, Klick, M, Kniffen, W, Knight, R, Kodzwa, D, Koenig, T, Komarovskiy, K, Kong, Y, Koontz, D, Krishnasamy, S, Krueger, E, Kuechenmeister, L, Kuehl, A, Kuettel, K, Kugler, D, Kulow, T, Kupriyanchik, I, Kuruvanka, T, Kushner, D, Kwon, E, Kwon, S, Kyle, M, Labryer, L, Labuda, J, Lafave, J, Laguerre, J, Laliberte, A, Lane, J, Langel, C, Lann, D, Largay, J, Latif, K, Latus, T, Lawrence, J, Ledger, G, Lee, Fg, Lee, E, Leffert, J, Leinung, M, Lenhard, Mj, Lentino, J, Leon, J, Leonard, M, Letassy, N, Leuck, K, Levin, P, Levinson, D, Lewis, M, Light, T, Lim, J, Lindamood, R, Lingvay, I, Lipps, J, Lisa, A, Livingston, Y, Llamas, L, Loesch, R, Long, T, Looby, R, Lopez, C, Lorenz, T, Lovre, D, Lu, P, Lucas, K, Luevano, G, Luidens, M, Luna, B, Luttrell, L, Lyons, T, Macadams, M, Mack, D, Mack, M, Madden, M, Madder, R, Madireddy, S, Mae, L, Mahakala, A, Maheshwari, H, Malbari, H, Maldonado, N, Mallitz, M, Mandviwala, M, Mann, K, Mardahay, M, Marino, J, Marney, A, Marshall, L, Martin, A, Martin, E, Martinez, G, Martinez-Miss, S, Marx, P, Massara, L, Mastoor, M, Matfin, G, Maturu, A, Maurides, P, May, M, Mayfield, R, Maynard, B, Mazza, A, Mccann, K, Mccoy, J, Mccoy, T, Mccullen, Mk, Mcdaniel, C, Mcdaniel, Am, Mcdermott, M, Mcdonald, A, Mcmasters, B, Mcmurray, C, Medlin, T, Meinel, M, Mendez, I, Menefee, J, Meredith, M, Merriweather, M, Mersey, J, Messino, C, Meyer, S, Meyers, L, Michael, D, Midyett, C, Miklius, A, Milford, E, Miller, B, Miller, H, Milligan, M, Minor, A, Miranda-Palma, B, Mirarchi, N, Mittadodla, S, Mittle, J, Moffat, A, Mohaupt, S, Mohiuddin, K, Mokshagundam, S, Monaco, S, Monsaert, R, Montano-Pereira, C, Montgomery, A, Moody, K, Moon, M, Moore, D, Moore, L, Morawski, E, Moreau, C, Morin, D, Moscoa, C, Motzkin, C, Mueller, R, Munoz, C, Munoz, M, Myneni, A, Naderi, B, Nagireddy, P, Naidu, J, Naidu, R, Naik, S, Naimark, R, Nardicchi, M, Ndukwu, I, Neller, C, Netten-Foster, L, Neumiller, J, New, T, Newman, S, Newton, T, Nguyen, B, Nicol, B, Nicol, P, Ninivaggi, L, Niswender, K, Norman, L, Noworatzky, G, Nyenwe, E, O'Brien, H, O'Connell, T, Oden, W, Odugbesan, A, Oliver, M, Oliver, T, Olmeda, C, O'Neil, C, Oremus, R, Ortega, T, Ortiz-Santos, S, Osborn, T, Padmanabhan, S, Papacostea, O, Park, I, Parker, A, Parker, K, Parker, R, Patel, C, Patel, M, Patel, R, Patino, M, Patterson, S, Paulson, K, Paz, A, Pemba, R, Pepe, C, Perez, J, Perez, T, Perry, D, Phillips, B, Phillips, J, Pickett, A, Pinson, M, Pitzer, R, Poduri, M, Poehls, J, Poteat, T, Powell, L, Prasad, S, Prevost, J, Price, E, Priest, D, Prieto, L, Purewal, T, Purighalla, R, Purighalla, U, Quadrel, M, Qureshi, A, Radhamma, R, Rafla, E, Rajab, H, Ramalingam, R, Ramirez, A, J, Ramirez, Ramirez, K, Ramirez, M, Randall, M, Rangaraj, U, Rao, V, Rasmussen, P, Rasouli, N, Ray, A, Reed, J, Rems, L, Renaud, K, Reno, M, Resnick, M, Reusch, J, Reynolds, L, Rhoton, K, Rhudy, J, Ricci, C, Rice, L, Richardson, A, Richardson, L, Rickard, H, Rickels, M, Riff, D, Rightenour, N, Risser, J, Rizvi, A, Robertson, J, Robinson, A, Robinson, R, Rockwell, M, Rodriguez, Jp, Rodriguez, M, Rojas, M, Rojas, W, Rooker-Morris, L, Root, C, Rose, M, Rosenberg, R, Rosenstock, J, Roth, M, Ruby, R, Sachson, R, Sack, P, Sadler, Rk, Sahai, S, J, Salazar, Salgam, M, Samal, A, Samson, A, Sanagorski, R, Sanchez, A, Sandberg, J, Sanderson, M, Sandoval, J, Santiago, E, Sapp, T, Saunders, J, Schill, J, Schott, C, Schreiman, R, Schu, D, Schuh, K, Schutta, M, Schwartz, J, Schweppe, L, Scofield, H, Scribner, A, Seal, J, Sealock, J, Seaton, B, Sedlak-Hanslik, T, Seekins, K, Segal, M, Seggelke, S, Semenza, S, Sentman, P, Serra, M, Seshadri, P, Sevilla, E, Shah, S, Shaheen, K, Shanik, M, Shaw, J, Sheets, M, Shellabarger, C, Sher, J, Shippey, J, Shivaswamy, V, Shomali, M, Shore, D, Shroff, P, Siddiqui, T, Siegwald, A, Silver, R, Simmons, D, Simons, R, Sinan, A, Singh, M, Sirinvaravong, S, Skero, J, Slover-Zipf, J, Small, S, Smith, B, Smith, K, Smith, M, Sohl, J, Solarz, Sh, Soler, D, Sood, A, Sora, N, Souchet, A, Soule, J, Sparks, J, Spector, L, Speicher, R, Spillers, L, Spivey, T, Springer, N, Sprouse, H, St John, J, Stacey, A, Stacey, H, Stafford, M, Stagner, E, Staples, K, Steadman, E, Steed, R, Steeves, G, Steinberg, H, Stell, C, Stirman, E, Straub, K, Strock, E, Sue, M, Suris, O, Sutton, T, Tabbah, I, Talsania, M, Tang, R, Tapia, J, Taylor, K, Taylor-Hancher, R, Teator, R, Tekateka, M, Temple, B, Temple, K, Teodori, M, Tharp, P, Thethi, T, Theuma, P, Thomas, S, Thottan, A, Thrasher, J, Thrasher, L, Tiemeyer, M, Tinney, I, Tobin, T, Toma, S, Tovar, M, Townsend, J, Trantow, C, Traylor, H, Trevino, M, Troy, M, Trumper, D, Tryggestad, J, Tucker, C, Turner, J, Turney, R, Tuten, C, Tyzack, J, Ullo, L, Underkofler, C, Unger, J, Urdanetta, R, Valdivia, V, Valenti, S, Vanderheiden, A, Vanderlinde-Wood, M, Varma, C, Vasquez, E, Vazquez, M, Vickery, D, Villafuerte, B, Villegas, C, Vivar, J, Vivekananthan, K, Vo, G, Vukojicic, K, Wachter, A, Wahl, D, Waitmann, J, Walker, D, Walsh, J, Walsh, K, Walton, A, Wang, A, Wardell, K, Watkins, S, Watkinson, J, Watts, M, Watwe, V, Weaver, N, Weber, R, Wedick, C, Weeks, D, Weeks, L, Weindorff, K, Weinstein, R, Weiss, S, Wenger, K, Wentworth, M, Werner, A, West, M, Whelan, S, White, B, White, J, Whitmire, M, Whittington, R, Wical, J, Wigley, C, Wilkins, F, Will, K, Williams, A, Wilson, Le, Wince, M, Wine, S, Winkle, P, Winner, C, Wise, J, Witte, M, Wittenmyer, J, Wood, C, Wood, R, Woodruff, C, Worthington, B, Wynn, D, Wysham, C, Xavier, P, Yela, S, Yenoby, L, Young, L, Younus, N, Yourell, V, Zaid, M, Zubair, I., Mann J.F.E., Orsted D.D., Brown-Frandsen K., Marso S.P., Poulter N.R., Rasmussen S., Tornoe K., Zinman B., Buse J.B., and Buscemi S.
- Subjects
Male ,Settore MED/09 - Medicina Interna ,Acute Kidney Injury ,Aged ,Albuminuria ,Creatinine ,Diabetes Mellitus, Type 2 ,Diabetic Nephropathies ,Double-Blind Method ,Female ,Follow-Up Studies ,Glomerular Filtration Rate ,Glucagon-Like Peptide 1 ,Humans ,Hypoglycemic Agents ,Intention to Treat Analysis ,Kidney Failure, Chronic ,Liraglutide ,Middle Aged ,Type 2 diabetes ,030204 cardiovascular system & hematology ,urologic and male genital diseases ,GLOMERULAR-FILTRATION-RATE ,KIDNEY-FUNCTION ,DISEASE ,law.invention ,Kidney Failure ,chemistry.chemical_compound ,0302 clinical medicine ,Randomized controlled trial ,law ,Medicine ,Settore MED/49 - Scienze Tecniche Dietetiche Applicate ,Chronic ,RISK ,Kidney ,Acute kidney injury ,11 Medical And Health Sciences ,General Medicine ,medicine.anatomical_structure ,TRIAL ,liraglutide, randomized controlled trial, type 2 diabetes, renal outcomes ,Life Sciences & Biomedicine ,Type 2 ,medicine.drug ,medicine.medical_specialty ,Renal function ,030209 endocrinology & metabolism ,CARDIOVASCULAR OUTCOMES ,Follow-Up Studie ,03 medical and health sciences ,Medicine, General & Internal ,General & Internal Medicine ,Diabetes mellitus ,Internal medicine ,Diabetes Mellitus ,Intensive care medicine ,Science & Technology ,business.industry ,MORTALITY ,medicine.disease ,INTENSIVE GLUCOSE CONTROL ,INDIVIDUALS ,chemistry ,Diabetic Nephropathie ,LEADER Steering Committee and Investigators ,business - Abstract
BACKGROUND: In a randomized, controlled trial that compared liraglutide, a glucagon-like peptide 1 analogue, with placebo in patients with type 2 diabetes and high cardiovascular risk who were receiving usual care, we found that liraglutide resulted in lower risks of the primary end point (nonfatal myocardial infarction, nonfatal stroke, or death from cardiovascular causes) and death. However, the long-term effects of liraglutide on renal outcomes in patients with type 2 diabetes are unknown. METHODS: We report the prespecified secondary renal outcomes of that randomized, controlled trial in which patients were assigned to receive liraglutide or placebo. The secondary renal outcome was a composite of new-onset persistent macroalbuminuria, persistent doubling of the serum creatinine level, end-stage renal disease, or death due to renal disease. The risk of renal outcomes was determined with the use of time-to-event analyses with an intention-to-treat approach. Changes in the estimated glomerular filtration rate and albuminuria were also analyzed. RESULTS: A total of 9340 patients underwent randomization, and the median follow-up of the patients was 3.84 years. The renal outcome occurred in fewer participants in the liraglutide group than in the placebo group (268 of 4668 patients vs. 337 of 4672; hazard ratio, 0.78; 95% confidence interval [CI], 0.67 to 0.92; P=0.003). This result was driven primarily by the new onset of persistent macroalbuminuria, which occurred in fewer participants in the liraglutide group than in the placebo group (161 vs. 215 patients; hazard ratio, 0.74; 95% CI, 0.60 to 0.91; P=0.004). The rates of renal adverse events were similar in the liraglutide group and the placebo group (15.1 events and 16.5 events per 1000 patient-years), including the rate of acute kidney injury (7.1 and 6.2 events per 1000 patient-years, respectively). CONCLUSIONS: This prespecified secondary analysis shows that, when added to usual care, liraglutide resulted in lower rates of the development and progression of diabetic kidney disease than placebo. (Funded by Novo Nordisk and the National Institutes of Health; LEADER ClinicalTrials.gov number, NCT01179048 .).
- Published
- 2017
33. Harnessing the patient voice in prostate cancer research: Using patient-reported outcomes in randomized controlled trials to support clinical decision-making
- Author
-
Van Hemelrijck, M., primary, Sparano, F., additional, Moris, L., additional, Beyer, K., additional, Cottone, F., additional, Sprangers, M., additional, and Efficace, F., additional
- Published
- 2019
- Full Text
- View/download PDF
34. PIONEER’s update and integration of a localised prostate cancer core outcome set for effectiveness trials and a standard set for clinical practice
- Author
-
Beyer, K., primary, Maclennan, S., additional, Lardas, M., additional, Moris, L., additional, Omar, M.I., additional, Maclennan, S.J., additional, Briganti, A., additional, and Van Hemelrijck, M., additional
- Published
- 2019
- Full Text
- View/download PDF
35. Genomic analysis of localized high-risk prostate cancer identifies XPO1 as a potential driver mechanism of metastatic progression
- Author
-
Moris, L., primary, Van Den Broeck, T., additional, Gevaert, T., additional, Smeets, E., additional, Helsen, C., additional, Handle, F., additional, Van Poppel, H., additional, Everaerts, W., additional, Lambrechts, D., additional, Buerki, C., additional, Davicioni, E., additional, Daelemans, D., additional, Joniau, S., additional, and Claessens, F., additional
- Published
- 2019
- Full Text
- View/download PDF
36. PIONEER’s systematic review of outcomes reported in effectiveness trials for interventions in locally advanced prostate cancer
- Author
-
Beyer, K., primary, Moris, L., additional, Lardas, M., additional, MacLennan, S., additional, Monagas, S., additional, Antunes-Lopes, T., additional, Vradi, E., additional, Omar, M.I., additional, MacLennan, S.J., additional, Briganti, A., additional, and Van Hemelrijck, M., additional
- Published
- 2019
- Full Text
- View/download PDF
37. The role of TET1 and hydroxymethylation in high-risk prostate cancer
- Author
-
Smeets, E., primary, Spans, L., additional, Moris, L., additional, Handle, F., additional, Helsen, C., additional, Gevaert, T., additional, Joniau, S., additional, and Claessens, F., additional
- Published
- 2019
- Full Text
- View/download PDF
38. Drivers and therapeutic vulnerabilities in AR indifferent anti-androgen resistant prostate cancer cells
- Author
-
Handle, F., primary, Prekovic, S., additional, Helsen, C., additional, Van Den Broeck, T., additional, Smeets, E., additional, Moris, L., additional, Eerlings, R., additional, El Kharraz, S., additional, Urbanucci, A., additional, Mills, I.G., additional, Joniau, S., additional, Attard, G., additional, and Claessens, F., additional
- Published
- 2019
- Full Text
- View/download PDF
39. Genomic analysis of localised prostate cancer identifies AZIN1 as driver of metastatic progression
- Author
-
Van Den Broeck, T., primary, Moris, L., additional, Gevaert, T., additional, Smeets, E., additional, Helsen, C., additional, Van Poppel, H., additional, Everaerts, W., additional, Lambrechts, D., additional, Buerki, C., additional, Davicioni, E., additional, Joniau, S., additional, and Claessens, F., additional
- Published
- 2019
- Full Text
- View/download PDF
40. Prognostic value of biochemical recurrence following treatment with curative intent for prostate cancer: A systematic review
- Author
-
Van Den Broeck, T., primary, Van Den Bergh, R.C.N., additional, Arfi, N., additional, Gross, T., additional, Moris, L., additional, Briers, E., additional, Cumberbatch, M.G.K., additional, De Santis, M., additional, Tilki, D., additional, Fanti, S., additional, Fossati, N., additional, Gillessen Sommer, S., additional, Grummet, J., additional, Henry, A., additional, Lardas, M., additional, Liew, M., additional, Rouvière, O., additional, Pecanka, J., additional, Mason, M., additional, Schoots, I.G., additional, Van der Kwast, T., additional, Van Der Poel, H.G., additional, Wiegel, T., additional, Willemse, P-P.M., additional, Yuan, Y., additional, Lam, T.B., additional, Cornford, P., additional, and Mottet, N., additional
- Published
- 2019
- Full Text
- View/download PDF
41. Effect of lidocaine and substance P on migration and proliferation 'in vitro' of human adipose derived stem cells (HascS) and breast cancer cells (mda-mb-231)
- Author
-
Pérez, Verónica López, Cassinello, F., Moris, L., Olmedillas, S., and Villagrasa, A.
- Abstract
Cassinello F.1, Moris L.2, Lu00f3pez Pu00e9rez V.2, Olmedillas S.3, Villagrasa A.3, Garcu00eda Arranz M.31Hospital Universitario Nuestra Seu00f1ora de Candelaria, Dept of Anaesthesiology, Santa Cruz de Tenerife, Spain, 2Fundaciu00f3n Jimu00e9nez Du00edaz, Dept of Anaesthesiology, Madrid, Spain,3Fundaciu00f3n Jimu00e9nez Du00edaz, New Therapies, Madrid, SpainTITLE: EFFECT OF LIDOCAINE AND SUBSTANCE P ON MIGRATION AND PROLIFERATION
- Published
- 2017
42. Serum IL-6,IL- 10 and substance P concentrations of patients administered distint anaesthetic techniques in breast cancer surgery
- Author
-
Pérez, Verónica López, Cassinello, F., and Moris, L.
- Abstract
Serum IL-6,IL- 10 and substance p concentrations of patients administered distint anaesthetic techniques in breast cu00e1ncer surgeryBackground : Breast cancer is one of the main causes of death between women. Even when surgery is supossed to be curative, patients can suffer from metastatic disease.A number of perioperative factors including anaesthetic technique might influence whether minimal residual micrometastases are eliminated o became full-blown metastasic disease.Apoptosis of tumoral cells is influenced by multiple factors, including inmune citoquine signalling. Many of these aspects can be modfified by anaesthesia.Goal of Study:To determine whether serum levels of cytokines can be modified by regional/propofol anaesthesia.Materials & Methods:20 women with diagnosis of breast cancer were randomized to receive either pectoral block with propofol anaesthesia (PEC) or general anesthesia with sevofluorane and opioids (GEN). Concentration of IL-6, IL-10 and substance P (SP) by using ELISA test were registered before induction, 1 h after surgery and 24h after surgery.Results :Fig I, II and III show levels of IL-6, 10 and SP for both types of anesthesia. Discussion: SP, and IL-6 stimulate tumor cell proliferation, migration and infiltration. IL-10 seems to inhibit cancer cell survival.It has been proposed that local anesthetic can attenuate cytokine response in cancer surgery, however we didnu00b4t find any association between type of anaesthesia and levels of il-6, il-10 or SP (p>0.5),.Conclusion: Maybe further studies should be necessary with a large number of patients to References: 1. Cancer surgery: how may anesthesia influence outcome? Cassinello, F; Prieto I;. Journal of clinical anesthesia 2015; 27 (3); 262-272
- Published
- 2017
43. Complete urinary tract extirpation: Oncological outcome
- Author
-
Muilwiik, T., primary, Akand, M., additional, Milenkovic, U., additional, Moris, L., additional, Demaegd, L., additional, Blyweert, W., additional, Van Poppel, H., additional, Albersen, M., additional, and Joniau, S., additional
- Published
- 2018
- Full Text
- View/download PDF
44. Correlation between the location of the index tumour and the location of positive lymph nodes in high-risk prostate cancer. A monocentric positive lymph node mapping study
- Author
-
Jacobs, B., primary, Vanneste, M., additional, Gevaert, T., additional, Laenen, A., additional, Van Den Broeck, T., additional, Moris, L., additional, Battaglia, A., additional, Albersen, M., additional, Claessens, F., additional, Lerut, E., additional, Haustermans, K., additional, Van Poppel, H., additional, De Meerleer, G., additional, Everaerts, W., additional, and Joniau, S., additional
- Published
- 2018
- Full Text
- View/download PDF
45. Feasibility of complete urinary tract extirpation
- Author
-
Muilwijk, T., primary, Akand, M., additional, Milenkovic, U., additional, Moris, L., additional, Demaegd, L., additional, Blyweert, W., additional, Van Poppel, H., additional, Albersen, M., additional, and Joniau, S., additional
- Published
- 2018
- Full Text
- View/download PDF
46. Genomic analysis of primary high-risk prostate cancer tumors with metastatic recurrence identifies antizyme inhibitor 1 as a regulator of cancer cell migration through regulation of collagen expression
- Author
-
Van Den Broeck, T., primary, Moris, L., additional, Gevaert, T., additional, Prekovic, S., additional, Tosco, L., additional, Smeets, E., additional, Lehrer, J., additional, Haddad, Z., additional, Helsen, C., additional, Margrave, J., additional, Boeckx, B., additional, Lambrechts, D., additional, Van Poppel, H., additional, Everaerts, W., additional, Chellisery, J., additional, Erho, N., additional, Buerki, C., additional, Davicioni, E., additional, Joniau, S., additional, and Claessens, F., additional
- Published
- 2018
- Full Text
- View/download PDF
47. The role of TET-mediated DNA hydroxymethylation in prostate cancer
- Author
-
Smeets, E., primary, Lynch, A.G., additional, Prekovic, S., additional, Van den Broeck, T., additional, Moris, L., additional, Helsen, C., additional, Joniau, S., additional, Claessens, F., additional, and Massie, C.E., additional
- Published
- 2018
- Full Text
- View/download PDF
48. Treatment-induced changes in the androgen receptor axis: Liquid biopsies as diagnostic/prognostic tools for prostate cancer
- Author
-
Prekovic, S., primary, Van den Broeck, T., additional, Moris, L., additional, Smeets, E., additional, Claessens, F., additional, Joniau, S., additional, Helsen, C., additional, and Attard, G., additional
- Published
- 2018
- Full Text
- View/download PDF
49. The survival impact of neoadjuvant hormonal therapy before radical prostatectomy for treatment of high-risk prostate cancer.
- Author
-
UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - (SLuc) Service d'urologie, Tosco, L, Laenen, A, Briganti, A, Gontero, P, Karnes, R J, Albersen, M, Bastian, P J, Chlosta, P, Claessens, F, Chun, F K, Everaerts, W, Gratzke, C, Graefen, M, Kneitz, B, Marchioro, G, Salas, R S, Tombal, Bertrand, Van den Broeck, T, Moris, L, Battaglia, A, van der Poel, H, Walz, J, Bossi, A, De Meerleer, G, Haustermans, K, Van Poppel, H, Spahn, M, Joniau, S, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - (SLuc) Service d'urologie, Tosco, L, Laenen, A, Briganti, A, Gontero, P, Karnes, R J, Albersen, M, Bastian, P J, Chlosta, P, Claessens, F, Chun, F K, Everaerts, W, Gratzke, C, Graefen, M, Kneitz, B, Marchioro, G, Salas, R S, Tombal, Bertrand, Van den Broeck, T, Moris, L, Battaglia, A, van der Poel, H, Walz, J, Bossi, A, De Meerleer, G, Haustermans, K, Van Poppel, H, Spahn, M, and Joniau, S
- Abstract
BACKGROUND: Several randomized controlled trials assessed the outcomes of patients treated with neoadjuvant hormonal therapy (NHT) before radical prostatectomy (RP). The majority of them included mainly low and intermediate risk prostate cancer (PCa) without specifically assessing PCa-related death (PCRD). Thus, there is a lack of knowledge regarding a possible effect of NHT on PCRD in the high-risk PCa population. We aimed to analyze the effect of NHT on PCRD in a multicenter high-risk PCa population treated with RP, using a propensity-score adjustment. METHODS: This is a retrospective multi-institutional study including patients with high-risk PCa defined as: clinical stage T3-4, PSA >20 ng ml-1 or biopsy Gleason score 8-10. We compared PCRD between RP and NHT+RP using competing risks analysis. Correction for group differences was performed by propensity-score adjustment. RESULTS: After application of the inclusion/exclusion criteria, 1573 patients remained for analysis; 1170 patients received RP and 403 NHT+RP. Median follow-up was 56 months (interquartile range 29-88). Eighty-six patients died of PCa and 106 of other causes. NHT decreased the risk of PCRD (hazard ratio (HR) 0.5; 95% confidence interval (CI) 0.32-0.80; P=0.0014). An interaction effect between NHT and radiotherapy (RT) was observed (HR 0.3; 95% CI 0.21-0.43; P<0.0008). More specifically, of patients who received adjuvant RT, those who underwent NHT+RP had decreased PCRD rates (2.3% at 5 year) compared to RP (7.5% at 5 year). The retrospective design and lack of specific information about NHT are possible limitations. CONCLUSIONS: In this propensity-score adjusted analysis from a large high-risk PCa population, NHT before surgery significantly decreased PCRD. This effect appeared to be mainly driven by the early addition of RT post-surgery. The specific sequence of NHT+RP and adjuvant RT merits further study in the high-risk PCa population.
- Published
- 2017
50. P058 - Initial steps of an online search tool development for diagnostic and prognostic factors in prostate cancer
- Author
-
Beyer, K., Moris, L., Lardas, M., Haire, A., Barletta, F., Scuderi, S., Molnar, M., Herrera, R., Rauf, A., Campi, R., Greco, I., Shiranov, K., Dabestani, S., Van Den Broeck, T.B., Sujenthiran, A., Gacci, M., Gandaglia, G., Omar, M.I., Maclennan, S., Roobol, M., Farahmand, B., Vradi, E., Devecsero, Z., Asiimwe, A., Zong, J., Maclennan, S.J., Collette, L., N’dow, J., Briganti, A., Bjartell, A., and Van Hemelrijck, M.
- Published
- 2020
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.