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Illicit drug production in clandestine laboratories involves the use of large quantities of different chemicals that can be obtained for legitimate purposes. The identification of these chemicals, including reagents, catalyzers and solvents, is crucial for forensic investigations. From a legal point of view, a drug precursor is a material that is specific and critical to the production of a finished chemical and that constitutes a significant portion of the final molecular structure of the drug. In this study, a gas chromatography quartz-enhanced photoacoustic spectroscopy (GC-QEPAS) sensor—in conjunction with a deep learning model—was evaluated for its effectiveness in the detection and identification of interesting compounds for the production of amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA), phenylcyclohexyl piperidine (PCP), and cocaine. The GC-QEPAS sensor includes a gas sampler, a fast GC for separation, and a QEPAS detector, which excites molecules exiting the GC column using a quantum cascade laser to provide the infra-red (IR) spectrum. The on-site capability of the GC-QEPAS system offers significant advantages over the current instruments employed in this field, including rapid analysis, which is crucial in field operations. This allows law enforcement to quickly identify specimens of interest on site. The system's performance was validated by taking into account the limit of detection, repeatability, and within-laboratory reproducibility. The results showed excellent repeatability and reproducibility for both the GC and QEPAS modules. The deep learning model, a multilayer perceptron neural network, was trained using IR spectra and retention times, achieving very high classification accuracy in the testing conditions. This study demonstrated the efficacy of the GC-QEPAS sensor combined with a deep learning model for the reliable identification of drug precursors, providing a robust tool for law enforcement during criminal investigations in clandestine laboratories. [ABSTRACT FROM AUTHOR]

An individual investor has to decide how to allocate his/her savings from a retirement perspective. This problem covers a long-term horizon. In this paper we consider a 40-year horizon formulating a multi-criteria multistage program with stochastic dominance constraints in an intermediate stage and in the final stage. As we are dealing with a real problem and we have formulated the model in cooperation with a commercial Italian bank, the intermediate stage corresponds to a possible withdrawal allowed by the Italian pension system. The sources of uncertainty considered are: the financial returns, the interest rate evolution, the investor's salary process and a considerable withdrawal event. We include a set of portfolio constraints according to the pension plan regulation. The objective of the model is to minimize the Average Value at Risk Deviation measure and to satisfy wealth goals. Three different wealth target formulations are considered: a deterministic wealth target (i.e. a comparison between the accumulated average wealth and a fixed threshold) and two stochastic dominance relations-the first order and the second order-introducing a benchmark portfolio and then requiring the optimal portfolio to dominate the benchmark. In particular, we prove that solutions obtained under stochastic dominance constraints ensure a safer allocation while still guaranteeing good returns. Moreover, we show how the withdrawal event affects the solution in terms of allocation in each of the three frameworks. Finally, the sensitivity and convergence of the stochastic solutions and computational issues are investigated. [ABSTRACT FROM AUTHOR]