1. [Hypogonadism and chronic obstructive pulmonary disease].
- Author
-
Vertkin AL, Morgunov LIu, and Shakhmanaev KhA
- Subjects
- Humans, Hypercapnia blood, Hypercapnia complications, Hypercapnia drug therapy, Hypercapnia physiopathology, Hypoxia blood, Hypoxia complications, Hypoxia drug therapy, Hypoxia physiopathology, Male, Testosterone therapeutic use, Androgens therapeutic use, Hypogonadism blood, Hypogonadism drug therapy, Hypogonadism etiology, Hypogonadism physiopathology, Pulmonary Disease, Chronic Obstructive blood, Pulmonary Disease, Chronic Obstructive complications, Pulmonary Disease, Chronic Obstructive drug therapy, Pulmonary Disease, Chronic Obstructive physiopathology, Testosterone analogs & derivatives, Testosterone blood
- Abstract
Chronic obstructive pulmonary disease (COPD) is a systemic disease that affects not only the respiratory system. Sex hormones deficiency in men can be correlated with the COPD stages and make a negative contribution during its progression. Up to date, there are no long-term trials evaluating the effects of androgens on the parameters of respiratory function in patients with COPD. Changes of testosterone levels in patients with COPD correlate with forced expiratory volume, and hypoxemia and hypercapnia levels. Glucocorticosteroids exacerbate androgen deficiency in patients with COPD, and the use of hormone replacement therapy with testosterone in these patients is justified. Androgens, in particular drug nebido, testosterone depot, can be effectively used in treatment and rehabilitation of patients with COPD.
- Published
- 2013