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Your search keyword '"Morgan, Bradley"' showing total 246 results

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1. Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy

2. Cardiac myosin inhibitor, CK-586, minimally reduces systolic function and ameliorates obstruction in feline hypertrophic cardiomyopathy

3. Pharmacokinetics of a single dose of Aficamten (CK‐274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model

4. Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy

6. Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility

7. Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

18. Pharmacokinetics of a single dose of Aficamten ( CK ‐274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model

19. Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin Activator for the Treatment of Impaired Muscle Function

20. Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy

21. Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on ?2 adrenoceptor

22. Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on β2 adrenoceptor

25. Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

27. Pharmacokinetics of a single dose of Aficamten (CK‐274) on cardiac contractility in a A31PMYBPC3 hypertrophic cardiomyopathy cat model.

29. Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin Activator for the Treatment of Impaired Muscle Function

31. Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy

34. Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases

36. Combined docking and machine learning identifies key molecular determinants of ligand pharmacological activity on β2 adrenoceptor

40. Characterization of the Cardiac Myosin Inhibitor CK-3773274: a Potential Therapeutic Approach for Hypertrophic Cardiomyopathy

44. Discovery of Potent, Non-Steroidal and Highly Selective Glucocorticoid Receptor Antagonists with Anti-Obesity Activity

45. Structure-based design of an inhibitor of the zinc peptidase thermolysin

50. Abstract 332: Pharmacologic Characterization of the Cardiac Myosin Inhibitor, CK-3773274: A Potential Therapeutic Approach for Hypertrophic Cardiomyopathy

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