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20,099 results on '"Moretto, A"'

2. A novel Mortar Method Integration using Radial Basis Functions

Author

Moretto, Daniele, Franceschini, Andrea, and Ferronato, Massimiliano

Subjects
Mathematics - Numerical Analysis
Abstract

The growing availability of computational resources has significantly increased the interest of the scientific community in performing complex multi-physics and multi-domain simulations. However, the generation of appropriate computational grids for such problems often remains one of the main bottlenecks. The use of a domain partitioning with non-conforming grids is a possible solution, which, however, requires the development of robust and efficient inter-grid interpolation operators to transfer a scalar or a vector field from one domain to another. This work presents a novel approach for interpolating quantities across non-conforming meshes within the framework of the classical mortar method, where weak continuity conditions are enforced. The key contribution is the introduction of a novel strategy that uses mesh-free Radial Basis Function (RBF) interpolations to compute the mortar integral, offering a compelling alternative to traditional projection-based methods. We propose an efficient algorithm tailored for complex three-dimensional settings allowing for potentially significant savings in the overall computational cost and ease of implementation, with no detrimental effects on the numerical accuracy. The formulation, analysis, and validation of the proposed RBF-based algorithm is discussed with the aid of a set of numerical examples, demonstrating its effectiveness. Furthermore, the details of the implementation are discussed and a test case involving a complex geometry is presented, to illustrate the applicability and advantages of our approach in real-world problems., Comment: 36 pages, 20 figures, 2 tables

Published
2024

5. Protective role of SARS-CoV-2 anti-S IgG against breakthrough infections among European healthcare workers during pre and post-Omicron surge—ORCHESTRA project

Author

Spiteri, Gianluca, D’Agostini, Marika, Abedini, Mahsa, Ditano, Giorgia, Collatuzzo, Giulia, Boffetta, Paolo, Vimercati, Luigi, Sansone, Emanuele, De Palma, Giuseppe, Modenese, Alberto, Gobba, Fabriziomaria, Liviero, Filippo, Moretto, Angelo, dell’Omo, Marco, Fiordi, Tiziana, Larese Filon, Francesca, Mauro, Marcella, Violán, Concepción, Mates, Dana, Oravec Bérešová, Jana, Monaco, Maria Grazia Lourdes, Carta, Angela, Verlato, Giuseppe, and Porru, Stefano

Published
2024
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6. A Novel Multi-Supplement Based on Guarana, Selenium, and L-Carnitine Reduces Organ-Specific Oxidative Stress But Not Oxidative Stress-Induced Anxiety

Author

Moretto, Joana Grandó, Vargas, Jose Eduardo, da Silva, Julia Spanhol, Pasinato, Aline Zuanazzi, Kunz, Jeferson Lisboa, Marengo, Paola, Teixeira, Cibele Ferreira, Azzolin, Verônica Farina, da Cruz, Ivana Beatrice Mânica, Trindade, Cristiano, Vargas, Verónica Inés, and Barcelos, Rômulo Pillon

Published
2024
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7. Displaying risk in mergers: a diagrammatic approach for exchange ratio determination

Author

Mainini, Alessandra, Moretto, Enrico, and Visetti, Daniela

Subjects
Quantitative Finance - General Finance
Abstract

This article extends, in a stochastic setting, previous results in the determination of feasible exchange ratios for merging companies. A first outcome is that shareholders of the companies involved in the merging process face both an upper and a lower bounds for acceptable exchange ratios. Secondly, in order for the improved `bargaining region' to be intelligibly displayed, the diagrammatic approach developed by Kulpa is exploited.

Published
2024

11. An international delphi survey and consensus meeting to define the risk factors for ureteral stricture after endoscopic treatment for urolithiasis

Author

Moretto, Stefano, Saita, A., Scoffone, C.M., Talso, M., Somani, B.K., Traxer, O., Angerri, O., Liatsikos, E., Ulvik, Y., Cracco, C.M., Keller., E.X., Pietropaolo, A., Tailly, T., Corrales, M., De Coninck, V., Nagele, U., Ferretti, S., Kronenberg, P., Carmignani, L., Osther, P.J., Goumas, I.K., Ajayi, L., Acquati, P., Perez-Fentes, D., Herrmann, T.R.W., and Buffi, N.M.

Published
2024
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14. Efficacy of multivitamin support following bariatric surgery in patients with obesity: a prospective observational study

Author

Basolo, Alessio, Bechi Genzano, Susanna, Vitti, Jacopo, Salvetti, Guido, Gilio, Donatella, Ceccarini, Giovanni, Scartabelli, Giovanna, Lippi, Chita, Bellini, Rosario, Mancini, Rudi, D’Imporzano, Simone, Moretto, Carlo, Angeli, Valentina, Troiani, Daniela, Fierabracci, Paola, Jaccheri, Roberta, Calderone, Alba, Poma, Anello M., Chiovato, Luca, Saponati, Giorgio, and Santini, Ferruccio

Published
2024
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15. Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago

Author

Perrone, Gennaro, Giuffrida, Mario, Abu-Zidan, Fikri, Kruger, Vitor F., Livrini, Marco, Petracca, Gabriele Luciano, Rossi, Giorgio, Tarasconi, Antonio, Tian, Brian W. C. A., Bonati, Elena, Mentz, Ricardo, Mazzini, Federico N., Campana, Juan P., Gasser, Elisabeth, Kafka-Ritsch, Reinhold, Felsenreich, Daniel M., Dawoud, Christopher, Riss, Stefan, Gomes, Carlos Augusto, Gomes, Felipe Couto, Gonzaga, Ricardo Alessandro Teixeira, Canton, Cassio Alfred Brattig, Pereira, Bruno Monteiro, Fraga, Gustavo P., Zem, Leticia Gonçalves, Cordeiro-Fonseca, Vinicius, de Mesquita Tauil, Renato, Atanasov, Boyko, Belev, Nikolay, Kovachev, Nikola, Meléndez, L. Juan José, Dimova, Ana, Dimov, Stefan, Zelić, Zdravko, Augustin, Goran, Bogdanić, Branko, Morić, Trpimir, Chouillard, Elie, Bajul, Melinda, De Simone, Belinda, Panis, Yves, Esposito, Francesco, Notarnicola, Margherita, Lauka, Lelde, Fabbri, Anna, Hentati, Hassen, Fnaiech, Iskander, Aurélien, Venara, Bougard, Marie, Roulet, Maxime, Demetrashvili, Zaza, Pipia, Irakli, Merabishvili, Giorgi, Bouliaris, Konstantinos, Koukoulis, Georgios, Doudakmanis, Christos, Xenaki, Sofia, Chrysos, Emmanuel, Kokkinakis, Stamatios, Vassiliu, Panteleimon, Michalopoulos, Nikolaos, Margaris, Ioannis, Kechagias, Aristotelis, Avgerinos, Konstantinos, Katunin, Jevgeni, Lostoridis, Eftychios, Nagorni, Eleni-Aikaterini, Pujante, Antonio, Mulita, Francesk, Maroulis, Ioannis, Vailas, Michail, Marinis, Athanasios, Siannis, Ioannis, Bourbouteli, Eirini, Manatakis, Dimitrios K., Tasis, Nikolaos, Acheimastos, Vasileios, Maria, Sotiropoulou, Stylianos, Kapiris, Kuzeridis, Harilaos, Korkolis, Dimitrios, Fradelos, Evangelos, Kavalieratos, George, Petropoulou, Thalia, Polydorou, Andreas, Papacostantinou, Ioannis, Triantafyllou, Tania, Kimpizi, Despina, Theodorou, Dimitrios, Toutouzas, Konstantinos, Chamzin, Alexandros, Frountzas, Maximos, Schizas, Dimitrios, Karavokyros, Ioannis, Syllaios, Athanasios, Charalabopoulos, Alexandros, Boura, Maria, Baili, Efstratia, Ioannidis, Orestis, Loutzidou, Lydia, Anestiadou, Elissavet, Tsouknidas, Ioannis, Petrakis, Georgios, Polenta, Eleni, Bains, Lovenish, Gupta, Rahul, Singh, Sudhir K., Khanduri, Archana, Bala, Miklosh, Kedar, Asaf, Pisano, Marcello, Podda, Mauro, Pisanu, Adolfo, Martines, Gennaro, Trigiante, Giuseppe, Lantone, Giuliano, Agrusa, Antonino, Di Buono, Giuseppe, Buscemi, Salvatore, Veroux, Massimiliano, Gioco, Rossella, Veroux, Gastone, Oragano, Luigi, Zonta, Sandro, Lovisetto, Federico, Feo, Carlo V., Pesce, Antonio, Fabbri, Nicolò, Lantone, Giulio, Marino, Fabio, Perrone, Fabrizio, Vincenti, Leonardo, Papagni, Vincenzo, Picciariello, Arcangelo, Rossi, Stefano, Picardi, Biagio, Del Monte, Simone Rossi, Visconti, Diego, Osella, Giulia, Petruzzelli, Luca, Pignata, Giusto, Andreuccetti, Jacopo, D’Alessio, Rossella, Buonfantino, Massimo, Guaitoli, Eleonora, Spinelli, Stefano, Sampietro, Gianluca Matteo, Corbellini, Carlo, Lorusso, Leonardo, Frontali, Alice, Pezzoli, Isabella, Bonomi, Alessandro, Chierici, Andrea, Cotsoglou, Christian, Manca, Giuseppe, Delvecchio, Antonella, Musa, Nicola, Casati, Massimiliano, Letizia, Laface, Abate, Emmanuele, Ercolani, Giorgio, D’Acapito, Fabrizio, Solaini, Leonardo, Guercioni, Gianluca, Cicconi, Simone, Sasia, Diego, Borghi, Felice, Giraudo, Giorgio, Sena, Giuseppe, Castaldo, Pasquale, Cardamone, Eugenia, Portale, Giuseppe, Zuin, Matteo, Spolverato, Ylenia, Esposito, Marialusia, Isernia, Roberta Maria, Di Salvo, Maria, Manunza, Romina, Esposito, Giuseppe, Agus, Marcello, Asti, Emanuele Luigi Giuseppe, Bernardi, Daniele Tiziano, Tonucci, Tommaso Panici, Luppi, Davide, Casadei, Massimiliano, Bonilauri, Stefano, Pezzolla, Angela, Panebianco, Annunziata, Laforgia, Rita, De Luca, Maurizio, Zese, Monica, Parini, Dario, Jovine, Elio, De Sario, Giuseppina, Lombardi, Raffaele, Aprea, Giovanni, Palomba, Giuseppe, Capuano, Marianna, Argenio, Giulio, Orio, Gianluca, Armellino, Mariano Fortunato, Troian, Marina, Guerra, Martina, Nagliati, Carlo, Biloslavo, Alan, Germani, Paola, Aizza, Giada, Monsellato, Igor, Chahrour, Ali Chaouki, Anania, Gabriele, Bombardini, Cristina, Bagolini, Francesco, Sganga, Gabriele, Fransvea, Pietro, Bianchi, Valentina, Boati, Paolo, Ferrara, Francesco, Palmieri, Francesco, Cianci, Pasquale, Gattulli, Domenico, Restini, Enrico, Cillara, Nicola, Cannavera, Alessandro, Nita, Gabriela Elisa, Sarnari, Jlenia, Roscio, Francesco, Clerici, Federico, Scandroglio, Ildo, Berti, Stefano, Cadeo, Alessandro, Filippelli, Alice, Conti, Luigi, Grassi, Carmine, Cattaneo, Gaetano Maria, Pighin, Marina, Papis, Davide, Gambino, Giovanni, Bertino, Vanessa, Schifano, Domenico, Prando, Daniela, Fogato, Luisella, Cavallo, Fabio, Ansaloni, Luca, Picheo, Roberto, Pontarolo, Nicholas, Depalma, Norma, Spampinato, Marcello, D’Ugo, Stefano, Lepre, Luca, Capponi, Michela Giulii, Campa, Rossella Domenica, Sarro, Giuliano, Dinuzzi, Vincenza Paola, Olmi, Stefano, Uccelli, Matteo, Ferrari, Davide, Inama, Marco, Moretto, Gianluigi, Fontana, Michele, Favi, Francesco, Picariello, Erika, Rampini, Alessia, Barberis, Andrea, Azzinnaro, Antonio, Oliva, Alba, Totaro, Luigi, Benzoni, Ilaria, Ranieri, Valerio, Capolupo, Gabriella Teresa, Carannante, Filippo, Caricato, Marco, Ronconi, Maurizio, Casiraghi, Silvia, Casole, Giovanni, Pantalone, Desire, Alemanno, Giovanni, Scheiterle, Maximilian, Ceresoli, Marco, Cereda, Marco, Fumagalli, Chiara, Zanzi, Federico, Bolzon, Stefano, Guerra, Enrico, Lecchi, Francesca, Cellerino, Paola, Ardito, Antonella, Scaramuzzo, Rosa, Balla, Andrea, Lepiane, Pasquale, Tartaglia, Nicola, Ambrosi, Antonio, Pavone, Giovanna, Palini, Gian Marco, Veneroni, Simone, Garulli, Gianluca, Ricci, Claudio, Torre, Beatrice, Russo, Iris Shari, Rottoli, Matteo, Tanzanu, Marta, Belvedere, Angela, Milone, Marco, Manigrasso, Michele, De Palma, Giovanni Domenico, Piccoli, Micaela, Pattacini, Gianmaria Casoni, Magnone, Stefano, Bertoli, Paolo, Pisano, Michele, Massucco, Paolo, Palisi, Marco, Luzzi, Andrea-Pierre, Fleres, Francesco, Clarizia, Guglielmo, Spolini, Alessandro, Kobe, Yoshiro, Toma, Takayuki, Shimamura, Fumihiko, Parker, Robert, Ranketi, Sinkeet, Mitei, Mercy, Svagzdys, Saulius, Pauzas, Henrikas, Zilinskas, Justas, Poskus, Tomas, Kryzauskas, Marius, Jakubauskas, Matas, Zakaria, Andee Dzulkarnaen, Zakaria, Zaidi, Wong, Michael Pak-Kai, Jusoh, Asri Che, Zakaria, Muhammad Nazreen, Cruz, Daniel Rios, Elizalde, Aurea Barbara Rodriguez, Reynaud, Alejandro Bañon, Hernandez, Edgard Efren Lozada, Monroy, Jose maria Victor Palomo, Hinojosa-Ugarte, Diego, Quiodettis, Martha, Du Bois, María Esther, Latorraca, José, Major, Piotr, Pędziwiatr, Michał, Pisarska-Adamczyk, Magdalena, Walędziak, Maciej, Kwiatkowski, Andrzej, Czyżykowski, Łukasz, da Costa, Silvia Dantas, Pereira, Bela, Ferreira, Ana Rita Oliveira, Almeida, Filipe, Rocha, Ricardo, Carneiro, Carla, Perez, Diego Pita, Carvas, João, Rocha, Catarina, Ferreira, Cátia, Marques, Rita, Fernandes, Urânia, Leao, Pedro, Goulart, André, Pereira, Rita Gonçalves, Patrocínio, Sara Daniela Direito, de Mendonça, Nuno Gonçalo Gonçalves, Manso, Maria Isabel Cerqueira, Morais, Henrique Manuel Cardoso, Cardoso, Paulo Sebastião, Calu, Valentin, Miron, Adrian, Toma, Elena Adelina, Gachabayov, Mahir, Abdullaev, Abakar, Litvin, Andrey, Nechay, Taras, Tyagunov, Alexander, Yuldashev, Anvar, Bradley, Alison, Wilson, Michael, Panyko, Arpád, Látečková, Zuzana, Lacko, Vladimír, Lesko, Dusan, Soltes, Marek, Radonak, Jozef, Turrado-Rodriguez, Victor, Termes-Serra, Roser, Morales-Sevillano, Xavier, Lapolla, Pierfrancesco, Mingoli, Andrea, Brachini, Gioia, Degiuli, Maurizio, Sofia, Silvia, Reddavid, Rossella, de Manzoni Garberini, Andrea, Buffone, Angelica, del Pozo, Eduardo Perea, Aparicio-Sánchez, Daniel, Dos Barbeito, Sandra, Estaire-Gómez, Mercedes, Vitón-Herrero, Rebeca, de los Ángeles Gil Olarte-Marquez, Mª, Gil-Martínez, José, Alconchel, Felipe, Nicolás-López, Tatiana, Rahy-Martin, Aida Cristina, Pelloni, María, Bañolas-Suarez, Raquel, Mendoza-Moreno, Fernando, Nisa, Francisca García-Moreno, Díez-Alonso, Manuel, Rodas, María Elisa Valle, Agundez, María Carmona, Andrés, María Inmaculada Pérez, Moreira, Claudia Cristina Lopes, Perez, Aintzane Lizarazu, Ponce, Iñigo Augusto, González-Castillo, Ana María, Membrilla-Fernández, Estela, Salvans, Silvia, Serradilla-Martín, Mario, Pardo, Pablo Sancho, Rivera-Alonso, Daniel, Dziakova, Jana, Huguet, Jose Mugüerza, Valle, Naila Pagès, Ruiz, Enrique Colás, Valcárcel, Cristina Rey, Moreno, Cristina Ruiz, Salazar, Yeniffer Tatiana Moreno, García, Juan Jesús Rubio, Micó, Silvia Sevila, López, Joaquín Ruiz, Farré, Silvia Pérez, Gomez, Maite Santamaria, Petit, Nuria Mestres, Titos-García, Alberto, Aranda-Narváez, Jose Manuel, Romacho-López, Laura, Sánchez-Guillén, Luis, Aranaz-Ostariz, Veronica, Bosch-Ramírez, Marina, Martínez-Pérez, Aleix, Martínez-López, Elías, Sebastián-Tomás, Juan Carlos, Jimenez-Riera, Granada, Jimenez-Vega, Javier, Cuellar, Jose Aurelio Navas, Campos-Serra, Andrea, Muñoz-Campaña, Anna, Gràcia-Roman, Raquel, Alegre, Javier Martínez, Pinto, Francisca Lima, O’Sullivan, Sara Nuñez, Antona, Francisco Blanco, Jiménez, Beatriz Muñoz, López-Sánchez, Jaime, Carmona, Zahira Gómez, Fernández, Rocio Torres, Sierra, Isabel Blesa, de León, Laura Román García, Moreno, Verónica Polaino, Iglesias, Eva, Cumplido, Paola Lora, Bravo, Altea Arango, Simó, Ignacio Rey, Domínguez, Carlota López, Caamaño, Aloia Guerreiro, Lozano, Rafael Calleja, Martínez, Manuel Durán, Torres, Álvaro Naranjo, de Quiros, Javier Tomas Morales Bernaldo, Pellino, Gianluca, Cloquell, Miriam Moratal, Moller, Elsa García, Jalal-Eldin, Sami, Abdoun, Ahmed K., Hamid, Hytham K. S., Lohsiriwat, Varut, Mongkhonsupphawan, Aitsariya, Baraket, Oussama, Ayed, Karim, Abbassi, Imed, Ali, Ali Ben, Ammar, Houssem, Kchaou, Ali, Tlili, Ahmed, Zribi, Imen, Colak, Elif, Polat, Suleyman, Koylu, Zehra Alan, Guner, Ali, Usta, Mehmet Arif, Reis, Murat Emre, Mantoglu, Baris, Gonullu, Emre, Akin, Emrah, Altintoprak, Fatih, Bayhan, Zulfu, Firat, Necattin, Isik, Arda, Memis, Ufuk, Bayrak, Mehmet, Altıntaş, Yasemin, Kara, Yasin, Bozkurt, Mehmet Abdussamet, Kocataş, Ali, Das, Koray, Seker, Ahmet, Ozer, Nazmi, Atici, Semra Demirli, Tuncer, Korhan, Kaya, Tayfun, Ozkan, Zeynep, Ilhan, Onur, Agackiran, Ibrahim, Uzunoglu, Mustafa Yener, Demirbas, Eren, Altinel, Yuksel, Meric, Serhat, Hacım, Nadir Adnan, Uymaz, Derya Salim, Omarov, Nail, Balık, Emre, Tebala, Giovanni D., Khalil, Hany, Rana, Mridul, Khan, Mansoor, Florence, Charlotte, Swaminathan, Christie, Leo, Cosimo Alex, Liasis, Lampros, Watfah, Josef, Trostchansky, Ivan, Delgado, Edward, Pontillo, Marcelo, Latifi, Rifat, Coimbra, Raul, Edwards, Sara, Lopez, Ana, Velmahos, George, Dorken, Ander, Gebran, Anthony, Palmer, Amanda, Oury, Jeffrey, Bardes, James M., Seng, Sirivan Suon, Coffua, Lauren S., Ratnasekera, Asanthi, Egodage, Tanya, Echeverria-Rosario, Karla, Armento, Isabella, Napolitano, Lena M., Sangji, Naveen F., Hemmila, Mark, Quick, Jacob A., Austin, Tyler R., Hyman, Theodore S., Curtiss, William, McClure, Amanda, Cairl, Nicholas, Biffl, Walter L., Truong, Hung P., Schaffer, Kathryn, Reames, Summer, Banchini, Filippo, Capelli, Patrizio, Coccolini, Federico, Sartelli, Massimo, Bravi, Francesca, Vallicelli, Carlo, Agnoletti, Vanni, Baiocchi, Gian Luca, and Catena, Fausto

Published
2024
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16. Ureteral stricture rate after endoscopic treatments for urolithiasis and related risk factors: systematic review and meta-analysis

Author

Moretto, S., Saita, A., Scoffone, C. M., Talso, M., Somani, B. K., Traxer, O., Angerri, O., Knoll, T., Liatsikos, E., Herrmann, T. R. W., Ulvik, Ø., Skolarikos, A., Cracco, C. M., Keller, E. X., Paciotti, M., Piccolini, A., Uleri, A., Tailly, T., Carmignani, L., Pietropaolo, A., Corrales, M., Lughezzani, G., Lazzeri, M., Fasulo, V., De Coninck, V., Arena, P., Nagele, U., Ferretti, S., Kronenberg, P., Perez-Fentes, D., Osther, P. J., Goumas, I. K., Acquati, P., Ajayi, L., Diana, P., Casale, P., and Buffi, N. M.

Published
2024
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17. Hemoadsorption improves kidney microcirculatory oxygenation and oxygen consumption, ameliorates tubular injury, and improves kidney function in a rat model of sepsis-induced AKI

Author

Bülent Ergin, Deniz Erol Kutucu, Aysegul Kapucu, Wijnie van Dam, Lorenza Moretto, Paul Heyman, and Can Ince

Subjects
AKI, Renal oxygenation, Renal perfusion, Tissue damage, Sepsis, Hemoadsorption, Medicine, Science
Abstract

Abstract Microcirculatory dysfunction, hypoxia, and inflammation are considered to be central in the pathogenesis of sepsis-induced acute kidney injury (AKI). In this experimental study, we hypothesized that extracorporeal removal of inflammatory cytokines by hemoadsorption (HA) therapy may mitigate renal injury associated with sepsis-induced AKI. To this end, we investigated renal microcirculatory oxygenation and perfusion, oxygen consumption, lactate, systemic hemodynamic variables, tubular cell integrity, inflammatory mediators, and kidney function in a rat model of septic AKI elicited by endotoxin infusion. Three groups of rats were investigated on extracorporeal circulation: HA only, LPS, and LPS + HA. Endotoxin infusion reduced cortex microcirculatory oxygenation and raised creatinine and lactate levels. Renal microcirculatory oxygenation, measured by two independent techniques (phosphorescence (µPO2) and spectrophotometry/Doppler (µHbO2sat and $$\mu \text{RBCv}$$ )), was ameliorated by HA therapy. The renal oxygen consumption, lactate and creatinine levels were restored in the LPS + HA group. A reduced amount of injured tubular cells was found in histological analysis of the kidneys. This experimental study demonstrated an improvement in multiple determinants of kidney oxygenation, damage, and systemic blood perfusion by HA in a clinically relevant rat model of septic AKI. Further studies are needed to optimize and support the clinical use of HA as a renal protective strategy.

Published
2024
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18. OPUS: An Integrated Assessment Model for Satellites and Orbital Debris

Author

Rao, Akhil, Moretto, Mark, Holzinger, Marcus, Kaffine, Daniel, and Weeden, Brian

Subjects
Physics - Space Physics, Economics - General Economics
Abstract

An increasingly salient public policy challenge is how to manage the growing number of satellites in orbit, including large constellations. Many policy initiatives have been proposed that attempt to address the problem from different angles, but there is a paucity of analytical tools to help policymakers evaluate the efficacy of these different proposals and any potential counterproductive outcomes. To help address this problem, this paper summarizes work done to develop an experimental integrated assessment model -- Orbital Debris Propagators Unified with Economic Systems (OPUS) -- that combines both astrodynamics of the orbital population and economic behavior of space actors. For a given set of parameters, the model first utilizes a given astrodynamic propagator to assess the state of objects in orbit. It then uses a set of user-defined economic and policy parameters -- e.g. launch prices, disposal regulations -- to model how actors will respond to the economic incentives created by a given scenario. For the purposes of testing, the MIT Orbital Capacity Tool (MOCAT) version 4S was used as the primary astrodynamics propagator to simulate the true expected target collision probability ($p_c$) for a given end-of-life (EOL) disposal plan. To demonstrate propagator-agnosticism, a Gaussian mixture probability hypothesis density (GMPHD) filter was also used to simulate $p_c$. We also explore economic policy instruments to improve both sustainability of and economic welfare from orbit use. In doing so, we demonstrate that this hybrid approach can serve as a useful tool for evaluating policy proposals for managing orbital congestion. We also discuss areas where this work can be made more robust and expanded to include additional policy considerations., Comment: This work was supported by 2022 grant funding from the NASA ROSES program. Code and simulation data available at https://github.com/akhilrao/OPUS

Published
2023

22. The C allele of the rs741301 polymorphism in the ELMO1 gene is associated with increased risk of diabetic retinopathy in patients with type 2 diabetes mellitus

Author

Luciane Moretto, Letícia de Almeida Brondani, Eliandra Girardi, Anna Carolina Meireles Vieira, Natália Emerim Lemos, Marilu Fiegenbaum, Luís Henrique Canani, Daisy Crispim, and Cristine Dieter

Subjects
Diabetic retinopathy, polymorphisms, ELMO1, Medicine, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Abstract

ABSTRACT Objective: To investigate the association of the rs741301 polymorphism in the ELMO1 gene with diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Materials and methods: This study analyzed 350 patients with T2DM and DR (cases) and 234 patients with T2DM without this complication but with more than 10 years of diabetes mellitus (DM) (controls). DR was diagnosed by indirect fundoscopy. Genotyping was performed by allelic discrimination real-time PCR. Results: The frequency of the C/C genotype of the rs741301 polymorphism in the ELMO1 gene was 26.9% in cases and 17.9% in controls (P = 0.011). After adjustment for covariables, the C/C genotype was associated with an increased risk of DR [odds ratio (OR) = 1.805, 95%CI 1.101–2.961; P = 0.019]. This association remained significant in dominant and additive inheritance models after adjustment for the same variables [OR = 1.597, 95%CI 1.089-2.343; P = 0.017; and OR = 1.818, 95%CI 1.099-3.007; P = 0.020]. Conclusion: This study demonstrated an association between the presence of the C allele of the ELMO1 rs741301 polymorphism and an increased risk of DR in patients with T2DM from Southern Brazil.

Published
2024
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23. Planificación 3D y corrección de deformidades del antebrazo en adolescentes con exostosis múltiple: Resultados clínicos

Author

Marcio Aurelio Aita, Fabio Lucas Rodrigues, Victor Bignatto Carvalho, Renato Tadeu Sassmannshausen Moretto, Kleber Oliveira Barbosa, and Ricardo Kaempf de Oliveira

Subjects
planificación 3D, alargamiento óseo, congénito, corrección de deformidad, planificación de deformidades, codo, osteocondromaidad, acortamiento relativo cubital, deformidad de la muñeca, 3D planning, bone lengthening, congenital, deformity correction, deformity planning, elbow, osteochondromaity, relative ulnar shortening, wrist deformity, Surgery, RD1-811
Abstract

A pesar de que entre el 30% y el 60% de los pacientes con exostosis cartilaginosa múltiple (ECM) presentan deformidad en el antebrazo, todavía no existe un consenso sobre el método preferido ni el momento ideal para el tratamiento, especialmente en pacientes adolescentes con múltiples lesiones, en quienes el momento del tratamiento puede tener un fuerte impacto psicológico, ya que el trastorno en el crecimiento óseo endocondral puede llevar a la inestabilidad articular y a deformidades graves de la extremidad afectada. El alargamiento del cúbito, la osteotomía del radio, la estabilización de la articulación radiocubital distal (ARCD) y la reducción de la cabeza radial pueden ser una buena estrategia para corregir la deformidad del miembro superior. Este estudio tuvo como objetivo mostrar una planificación y un procedimiento reproducibles para corregir la deformidad del radio, la subluxación de la articulación radiocapitelar, el cúbito minus, el equilibrio carpiano y la incongruencia de la ARCD en adolescentes tratados con el protocolo ABC (fijación externa híbrida y placa volar de radio utilizando un modelo 3D y métodos de planificación por software) en cinco adolescentes con ECM y deformidad en el antebrazo. Después de un año de la cirugía, los pacientes mostraron una puntuación DASH de 8 y una puntuación EVA de 1. En el examen radiográfico, el ángulo articular radial (AAR) fue de 21,55°, la inclinación palmar de 10°, la variación cubital (VC) de 1,2 mm, el deslizamiento carpiano (DC) de 64%, el centro de rotación de la angulación (CORA) de 1,1° hacia el cúbito / 21,95° hacia el radio, y el arqueamiento radial (AR) de 11,45 mm. La tasa de complicaciones fue del 20% (un paciente) que fue sometido a un re-alargamiento del cúbito para mejorar la congruencia de la ARCD. Se encontró que el protocolo ABC (fijación externa híbrida y placa volar de radio utilizando un modelo 3D y un sistema de planificación por software) es un método de tratamiento seguro y confiable para la deformidad del antebrazo en adolescentes con ECM.

Published
2024
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24. O oral no livro didático de língua portuguesa: uma análise das dimensões constitutivas do gênero palestra

Author

Marina de Fátima Ferreira Nascimento and Milena Moretto

Subjects
gêneros discursivos/textuais orais, livro didático, análise dialógica do discurso, Philology. Linguistics, P1-1091
Abstract

RESUMO O presente artigo tematiza as formas como o livro didático de Língua Portuguesa “Se liga na língua (7º ano)”, suporte fundamental aos processos de ensino e de aprendizagem de língua materna no município de Itatiba, sugere a abordagem dos gêneros discursivos/textuais orais nos Anos Finais do Ensino Fundamental. Tomando como exemplo um capítulo apresentado pela coleção didática “Se liga na língua, leitura, produção de texto e linguagem, 2018”, adotada no PNLD 2019, que tematiza o gênero palestra, temos como objetivo geral compreender se as propostas de ensino nele apresentadas possibilitam o desenvolvimento da apropriação das dimensões constitutivas desse gênero. Pautando-nos na perspectiva enunciativo-discursiva, evidenciamos, no contexto mais amplo, que há, em toda coleção, uma escassez tanto quantitativa quanto qualitativa dos gêneros discursivos/textuais orais disponibilizados no livro didático e que as atividades nele apresentadas em relação ao ensino do oral não explora adequadamente as dimensões constitutivas do gênero, no caso desse artigo, o gênero palestra.

Published
2024
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25. Downlink TDMA Scheduling for IRS-aided Communications with Block-Static Constraints

Author

Rech, Alberto, Pagin, Matteo, Tomasin, Stefano, Moretto, Federico, Badia, Leonardo, Giordani, Marco, Gambini, Jonathan, and Zorzi, Michele

Subjects
Electrical Engineering and Systems Science - Signal Processing, Computer Science - Networking and Internet Architecture
Abstract

Intelligent reflecting surfaces (IRSs) are being studied as possible low-cost energy-efficient alternatives to active relays, with the goal of solving the coverage issues of millimeter wave (mmWave) and terahertz (THz) network deployments. In the literature, these surfaces are often studied by idealizing their characteristics. Notably, it is often assumed that IRSs can tune with arbitrary frequency the phase-shifts induced by their elements, thanks to a wire-like control channel to the next generation node base (gNB). Instead, in this work we investigate an IRS-aided time division multiple access (TDMA) cellular network, where the reconfiguration of the IRS may entail an energy or communication cost, and we aim at limiting the number of reconfigurations over time. We develop a clustering-based heuristic scheduling, which optimizes the system sum-rate subject to a given number of reconfigurations within the TDMA frame. To such end, we first cluster user equipments (UEs) with a similar optimal IRS configuration. Then, we compute an overall IRS cluster configuration, which can be thus kept constant while scheduling the whole UEs cluster. Numerical results show that our approach is effective in supporting IRSs-aided systems with practical constraints, achieving up to 85% of the throughput obtained by an ideal deployment, while providing a 50% reduction in the number of IRS reconfigurations., Comment: 6 pages, 4 figures, submitted to WCNC 2023 Workshops

Published
2023

26. KRASG12D-Mutated Metastatic Colorectal Cancer: Clinical, Molecular, Immunologic, and Prognostic Features of a New Emerging Targeted Alteration

Author

Moretto, Roberto, Rossini, Daniele, Murgioni, Sabina, Ciracì, Paolo, Nasca, Vincenzo, Germani, Marco Maria, Calegari, Maria Alessandra, Vetere, Guglielmo, Intini, Rossana, Taravella, Ada, Studiale, Vittorio, Boccaccio, Chiara, Passardi, Alessandro, Tamburini, Emiliano, Zaniboni, Alberto, Salvatore, Lisa, Pietrantonio, Filippo, Lonardi, Sara, Masi, Gianluca, and Cremolini, Chiara

Published
2024
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27. Studying the interaction between VUV photons and PAHs in relevant astrophysical conditions

Author

Marciniak, A, Bonnamy, A, Zamith, S, Noguès, L, Coeur-Joly, O, Murat, D, Moretto-Capelle, P, l'Hermite, J. -M, Mulas, G, and Joblin, C

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Chemical Physics
Abstract

PIRENEA and PIRENEA 2 are experimental setups dedicated to the study of fundamental molecular processes involving species of astrochemical interest. The coupling of a VUV source to PIRENEA has allowed us to study the fragmentation pathways and stability of polycyclic aromatic hydrocarbons (PAHs) containing aliphatic bonds under conditions relevant for astrophysical photodissociation regions. PIRE-NEA 2 will open the possibility to extend these studies to larger systems such as PAH clusters, and more generally to study gas-nanograin-photon interactions., Comment: Book Series: Astrophysics and Space Science Proceedings (ASSSP)

Published
2022

30. Nutrition in ARDS, COVID-19, and ECMO

Author

Moretto, Lorenza, Bombino, Michela, Gianotti, Luca, Rezoagli, Emanuele, Cotoia, Antonella, editor, De Rosa, Silvia, editor, Ferrari, Fiorenza, editor, Pota, Vincenzo, editor, and Umbrello, Michele, editor

Published
2024
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32. Ectomycorrhizal fungi and the nitrogen economy of Nothofagus in southern Patagonia

Author

Camille Truong, Luciano A. Gabbarini, Alicia Moretto, Julio M. Escobar, and Matthew E. Smith

Subjects
leaf phenology, mycorrhizal associations, Nothofagaceae, nutrient cycling, soil fertility, southern hemisphere, Ecology, QH540-549.5
Abstract

Abstract Subantarctic Nothofagus forests are the southernmost forests in the world, with negligible atmospheric nitrogen (N) deposition. Most paradigms about the role of ectomycorrhizal (ECM) fungi in N cycling and plant N uptake at high latitudes have been tested in boreal coniferous forests, while in the southern hemisphere, ECM hosts are primarily angiosperms. Using ITS1 meta‐barcoding, we characterized ECM and saprotrophic fungal communities in evergreen and deciduous Nothofagus forests forming monodominant and mixed stands in the archipelago of Tierra del Fuego (Chile and Argentina). We assessed the N economy of Nothofagus by correlating host species with fungal relative abundances, edaphic variables, net N mineralization, microbial biomass N and the activity of eight extracellular soil enzymes activities. The N economy of deciduous N. pumilio forests was strikingly similar to boreal coniferous forests, with the lowest inorganic N availability and net N mineralization, in correlation to higher relative abundances of ECM fungi with enzymatic capacity for organic N mobilization (genus Cortinarius). In contrast, the N economy of evergreen N. betuloides forests was predominantly inorganic and correlated with ECM lineages from the family Clavulinaceae, in acidic soils with poor drainage. Grassy understory vegetation in deciduous N. antarctica forests likely promoted saprotrophic fungi (i.e., genus Mortierella) in correlation with higher activities of carbon‐degrading enzymes. Differences between Nothofagus hosts did not persist in mixed forests, illustrating the range of soil fertility of these ECM angiosperms and the underlying effects of soil and climate on Nothofagus distribution and N cycling in southern Patagonia.

Published
2024
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33. Achievements and Lessons Learned from Successful Small Satellite Missions for Space Weather-Oriented Research

Author

Spence, Harlan E., Caspi, Amir, Bahcivan, Hasan, Nieves-Chinchilla, Jesus, Crowley, Geoff, Cutler, James, Fish, Chad, Jackson, David, Jørgensen, Therese Moretto, Klumpar, David, Li, Xinlin, Mason, James P., Paschalidis, Nick, Sample, John, Smith, Sonya, Swenson, Charles M., and Woods, Thomas N.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics, Physics - Space Physics
Abstract

When the first CubeSats were launched nearly two decades ago, few people believed that the miniature satellites would likely prove to be a useful scientific tool. Skeptics abounded. However, the last decade has seen the highly successful implementation of space missions that make creative and innovative use of fast-advancing CubeSat and small satellite technology to carry out important science experiments and missions. Several projects now have used CubeSats to obtain first-of-their-kind observations and findings that have formed the basis for high-profile engineering and science publications, thereby establishing without doubt the scientific value and broad utility of CubeSats. In this paper, we describe recent achievements and lessons learned from a representative selection of successful CubeSat missions with a space weather focus. We conclude that these missions were successful in part because their limited resources promoted not only mission focus but also appropriate risk-taking for comparatively high science return. Quantitative analysis of refereed publications from these CubeSat missions and several larger missions reveals that mission outcome metrics compare favorably when publication number is normalized by mission cost or if expressed as a weighted net scientific impact of all mission publications., Comment: 35 pages, 5 figures, 1 table; accepted for publication by Space Weather Journal

Published
2022
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34. Corrigendum: Transcriptomic drivers of differentiation, maturation, and polyploidy in human extravillous trophoblast

Author

Morey, Robert, Farah, Omar, Kallol, Sampada, Requena, Daniela F, Meads, Morgan, Moretto-Zita, Matteo, Soncin, Francesca, Laurent, Louise C, and Parast, Mana M

Subjects
Biological Sciences, Biomedical and Clinical Sciences, Genetics, extravillous trophoblast, placenta, polyploid, senescence, cytotrophoblast, Biological sciences, Biomedical and clinical sciences
Abstract

[This corrects the article DOI: 10.3389/fcell.2021.702046.].

Published
2023

37. A Propensity Score–matched Comparison of Micro-ultrasound–guided Transrectal and Magnetic Resonance Imaging/Transrectal Ultrasound Fusion-guided Transperineal Prostate Biopsies for Detection of Clinically Significant Prostate Cancer

Author

Piccolini, Andrea, Avolio, Pier Paolo, Saitta, Cesare, Beatrici, Edoardo, Moretto, Stefano, Aljoulani, Muhannad, Dagnino, Filippo, Maffei, Davide, Frego, Nicola, Fasulo, Vittorio, Paciotti, Marco, Hurle, Rodolfo, Saita, Alberto, Lazzeri, Massimo, Casale, Paolo, Colombo, Piergiuseppe, Cieri, Miriam, Buffi, Nicolò Maria, and Lughezzani, Giovanni

Published
2024
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43. End-to-End Simulation of 5G Networks Assisted by IRS and AF Relays

Author

Pagin, Matteo, Giordani, Marco, Gargari, Amir Ashtari, Rech, Alberto, Moretto, Federico, Tomasin, Stefano, Gambini, Jonathan, and Zorzi, Michele

Subjects
Computer Science - Networking and Internet Architecture, Electrical Engineering and Systems Science - Signal Processing
Abstract

The high propagation and penetration loss experienced at millimeter wave (mmWave) frequencies requires ultra-dense deployments of 5th generation (5G) base stations, which may be infeasible and costly for network operators. Integrated Access and Backhaul (IAB) has been proposed to partially address this issue, even though raising concerns in terms of power consumption and scalability. Recently, the research community has been investigating Intelligent Reflective Surfaces (IRSs) and Amplify-and-Forward (AF) relays as more energy-efficient alternatives to solve coverage issues in 5G scenarios. Along these lines, this paper relies on a new simulation framework, based on ns-3, to simulate IRS/AF systems with a full-stack, end-to-end perspective, with considerations on to the impact of the channel model and the protocol stack of 5G NR networks. Our goal is to demonstrate whether these technologies can be used to relay 5G traffic requests and, if so, how to dimension IRS/AF nodes as a function of the number of end users., Comment: Submitted to IEEE for possible publication. 8 pages, 7 figures

Published
2022

45. What Is the Long-Term, Real-World Value of CBL? Assessing Impact from the Perspective of Former Students

Author

Lake, Danielle, Lowen, Aaron, Moretto, Kristin, and Youker, Brandon W.

Abstract

This study examines the post-course impact of community-based learning (CBL) on undergraduate students enrolled in a CBL course from one of four undergraduate degree programs at a large, public university. Mixed methods analysis of survey and interview data show that CBL experiences supported holistic development for students, including in the areas of civic, personal, professional, and academic growth, while also highlighting the value of team- and project-based CBL and "real-world" skill building. Results also show faculty experience significantly affects students' perceived outcomes.

Published
2021

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