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134 results on '"Moreno-Alcázar, Ana"'

1. Promoting employee wellbeing and preventing non-clinical mental health problems in the workplace: a preparatory consultation survey

Author

Coppens, Evelien, Hogg, Bridget, Greiner, Birgit A., Paterson, Charlotte, de Winter, Lars, Mathieu, Sharna, Cresswell-Smith, Johanna, Aust, Birgit, Leduc, Caleb, Van Audenhove, Chantal, Pashoja, Arlinda C., Kim, Dooyoung, Reich, Hanna, Fanaj, Naim, Dushaj, Arilda, Thomson, Katherine, O’Connor, Cliodhna, Moreno-Alcázar, Ana, Amann, Benedikt L., and Arensman, Ella

Published
2023
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2. Supporting employees with mental illness and reducing mental illness-related stigma in the workplace: an expert survey

Author

Hogg, Bridget, Moreno-Alcázar, Ana, Tóth, Mónika Ditta, Serbanescu, Ilinca, Aust, Birgit, Leduc, Caleb, Paterson, Charlotte, Tsantilla, Fotini, Abdulla, Kahar, Cerga-Pashoja, Arlinda, Cresswell-Smith, Johanna, Fanaj, Naim, Meksi, Andia, Ni Dhalaigh, Doireann, Reich, Hanna, Ross, Victoria, Sanches, Sarita, Thomson, Katherine, Van Audenhove, Chantal, Pérez, Victor, Arensman, Ella, Purebl, Gyorgy, and Amann, Benedikt L.

Published
2023
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4. EMDR therapy vs. supportive therapy as adjunctive treatment in trauma-exposed bipolar patients: A randomised controlled trial

Author

Hogg, Bridget, Radua, Joaquim, Gardoki-Souto, Itxaso, Fontana-McNally, Marta, Lupo, Walter, Reinares, María, Jiménez, Esther, Madre, Mercè, Blanco-Presas, Laura, Cortizo, Romina, Massó-Rodriguez, Anna, Castaño, Juan, Argila, Isabel, Castro-Rodriguez, José Ignacio, Comes, Mercè, Macias, Cristina, Sánchez-González, Roberto, Mur-Mila, Estanislao, Novo, Patricia, Rosa, Adriane R., Vieta, Eduard, Padberg, Frank, Pérez-Solà, Victor, Valiente-Gómez, Alicia, Moreno-Alcázar, Ana, and Amann, Benedikt L.

Published
2023
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11. EMDR therapy vs. Supportive Therapy as adjunctive treatment in trauma-exposed bipolar patients: a randomized controlled trial.

Author

Hogg, Bridget, primary, Radua, Joaquim, additional, Gardoki-Souto, Itxaso, additional, Fontana-McNally, Marta, additional, Lupo, Walter, additional, Reinares, María, additional, Jiménez, Esther, additional, Madre, Mercè, additional, Blanco-Presas, Laura, additional, Cortizo, Romina, additional, Massó-Rodríguez, Anna, additional, Castaño, Juan, additional, Argila, Isabel, additional, Castro-Rodríguez, José Ignacio, additional, Comes, Mercè, additional, Macias, Cristina, additional, Sánchez-González, Roberto, additional, Mur, Estanislao, additional, Novo, Patricia, additional, Rosa, Adriane Ribeiro, additional, Vieta, Eduard, additional, Padberg, Frank, additional, Pérez-Solà, Victor, additional, Valiente-Gómez, Alicia, additional, Moreno-Alcázar, Ana, additional, and Amann, Benedikt L, additional

Published
2023
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12. Le statut actuel de la thérapie EMDR, les domaines cibles spécifiques et les objectifs pour l’avenir

Author

Matthijssen, Suzy J. M. A., primary, Lee, Christopher W., additional, Roos, Carlijn de, additional, Barron, Ian G., additional, Jarero, Ignacio, additional, Shapiro, Elan, additional, Hurley, E. C., additional, Schubert, Sarah J., additional, Baptist, Joyce, additional, Amann, Benedikt L., additional, Moreno-Alcázar, Ana, additional, Tesarz, Jonas, additional, and Jongh, Ad de, additional

Published
2023
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14. Prevalence and Characterization of Psychological Trauma in Patients with Fibromyalgia: A Cross-Sectional Study

Author

Gardoki-Souto, Itxaso, primary, Redolar-Ripoll, Diego, additional, Fontana, Marta, additional, Hogg, Bridget, additional, Castro, María José, additional, Blanch, Josep M., additional, Ojeda, Fabiola, additional, Solanes, Aleix, additional, Radua, Joaquim, additional, Valiente-Gómez, Alicia, additional, Cirici, Roser, additional, Pérez, Víctor, additional, Amann, Benedikt L., additional, and Moreno-Alcázar, Ana, additional

Published
2022
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15. High incidence of PTSD diagnosis and trauma-related symptoms in a trauma exposed bipolar I and II sample

Author

Hogg, Bridget, primary, Valiente-Gómez, Alicia, additional, Redolar-Ripoll, Diego, additional, Gardoki-Souto, Itxaso, additional, Fontana-McNally, Marta, additional, Lupo, Walter, additional, Jiménez, Esther, additional, Madre, Mercè, additional, Blanco-Presas, Laura, additional, Reinares, María, additional, Cortizo, Romina, additional, Massó-Rodriguez, Anna, additional, Castaño, Juan, additional, Argila, Isabel, additional, Castro-Rodríguez, José Ignacio, additional, Comes, Mercè, additional, Doñate, Marta, additional, Herrería, Elvira, additional, Macias, Cristina, additional, Mur, Estanislao, additional, Novo, Patricia, additional, Rosa, Adriane R., additional, Vieta, Eduard, additional, Radua, Joaquim, additional, Padberg, Frank, additional, Pérez-Solà, Victor, additional, Moreno-Alcázar, Ana, additional, and Amann, Benedikt L., additional

Published
2022
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16. Virtual Ontogeny of Cortical Growth Preceding Mental Illness

Author

Patel, Yash, primary, Shin, Jean, additional, Abé, Christoph, additional, Agartz, Ingrid, additional, Alloza, Clara, additional, Alnæs, Dag, additional, Ambrogi, Sonia, additional, Antonucci, Linda A., additional, Arango, Celso, additional, Arolt, Volker, additional, Auzias, Guillaume, additional, Ayesa-Arriola, Rosa, additional, Banaj, Nerisa, additional, Banaschewski, Tobias, additional, Bandeira, Cibele, additional, Başgöze, Zeynep, additional, Cupertino, Renata Basso, additional, Bau, Claiton H.D., additional, Bauer, Jochen, additional, Baumeister, Sarah, additional, Bernardoni, Fabio, additional, Bertolino, Alessandro, additional, Bonnin, Caterina del Mar, additional, Brandeis, Daniel, additional, Brem, Silvia, additional, Bruggemann, Jason, additional, Bülow, Robin, additional, Bustillo, Juan R., additional, Calderoni, Sara, additional, Calvo, Rosa, additional, Canales-Rodríguez, Erick J., additional, Cannon, Dara M., additional, Carmona, Susanna, additional, Carr, Vaughan J., additional, Catts, Stanley V., additional, Chenji, Sneha, additional, Chew, Qian Hui, additional, Coghill, David, additional, Connolly, Colm G., additional, Conzelmann, Annette, additional, Craven, Alexander R., additional, Crespo-Facorro, Benedicto, additional, Cullen, Kathryn, additional, Dahl, Andreas, additional, Dannlowski, Udo, additional, Davey, Christopher G., additional, Deruelle, Christine, additional, Díaz-Caneja, Covadonga M., additional, Dohm, Katharina, additional, Ehrlich, Stefan, additional, Epstein, Jeffery, additional, Erwin-Grabner, Tracy, additional, Eyler, Lisa T., additional, Fedor, Jennifer, additional, Fitzgerald, Jacqueline, additional, Foran, William, additional, Ford, Judith M., additional, Fortea, Lydia, additional, Fuentes-Claramonte, Paola, additional, Fullerton, Janice, additional, Furlong, Lisa, additional, Gallagher, Louise, additional, Gao, Bingchen, additional, Gao, Si, additional, Goikolea, Jose M., additional, Gotlib, Ian, additional, Goya-Maldonado, Roberto, additional, Grabe, Hans J., additional, Green, Melissa, additional, Grevet, Eugenio H., additional, Groenewold, Nynke A., additional, Grotegerd, Dominik, additional, Gruber, Oliver, additional, Haavik, Jan, additional, Hahn, Tim, additional, Harrison, Ben J., additional, Heindel, Walter, additional, Henskens, Frans, additional, Heslenfeld, Dirk J., additional, Hilland, Eva, additional, Hoekstra, Pieter J., additional, Hohmann, Sarah, additional, Holz, Nathalie, additional, Howells, Fleur M., additional, Ipser, Jonathan C., additional, Jahanshad, Neda, additional, Jakobi, Babette, additional, Jansen, Andreas, additional, Janssen, Joost, additional, Jonassen, Rune, additional, Kaiser, Anna, additional, Kaleda, Vasiliy, additional, Karantonis, James, additional, King, Joseph A., additional, Kircher, Tilo, additional, Kochunov, Peter, additional, Koopowitz, Sheri-Michelle, additional, Landén, Mikael, additional, Landrø, Nils Inge, additional, Lawrie, Stephen, additional, Lebedeva, Irina, additional, Luna, Beatriz, additional, Lundervold, Astri J., additional, MacMaster, Frank P., additional, Maglanoc, Luigi A., additional, Mathalon, Daniel H., additional, McDonald, Colm, additional, McIntosh, Andrew, additional, Meinert, Susanne, additional, Michie, Patricia T., additional, Mitchell, Philip, additional, Moreno-Alcázar, Ana, additional, Mowry, Bryan, additional, Muratori, Filippo, additional, Nabulsi, Leila, additional, Nenadić, Igor, additional, O'Gorman Tuura, Ruth, additional, Oosterlaan, Jaap, additional, Overs, Bronwyn, additional, Pantelis, Christos, additional, Parellada, Mara, additional, Pariente, Jose C., additional, Pauli, Paul, additional, Pergola, Giulio, additional, Piarulli, Francesco Maria, additional, Picon, Felipe, additional, Piras, Fabrizio, additional, Pomarol-Clotet, Edith, additional, Pretus, Clara, additional, Quidé, Yann, additional, Radua, Joaquim, additional, Ramos-Quiroga, J. Antoni, additional, Rasser, Paul E., additional, Reif, Andreas, additional, Retico, Alessandra, additional, Roberts, Gloria, additional, Rossell, Susan, additional, Rovaris, Diego Luiz, additional, Rubia, Katya, additional, Sacchet, Matthew D., additional, Salavert, Josep, additional, Salvador, Raymond, additional, Sarró, Salvador, additional, Sawa, Akira, additional, Schall, Ulrich, additional, Scott, Rodney, additional, Selvaggi, Pierluigi, additional, Silk, Tim, additional, Sim, Kang, additional, Skoch, Antonin, additional, Spalletta, Gianfranco, additional, Spaniel, Filip, additional, Stein, Dan J., additional, Steinsträter, Olaf, additional, Stolicyn, Aleks, additional, Takayanagi, Yoichiro, additional, Tamm, Leanne, additional, Tavares, Maria, additional, Teumer, Alexander, additional, Thiel, Katharina, additional, Thomopoulos, Sophia I., additional, Tomecek, David, additional, Tomyshev, Alexander S., additional, Tordesillas-Gutiérrez, Diana, additional, Tosetti, Michela, additional, Uhlmann, Anne, additional, Van Rheenen, Tamsyn, additional, Vazquez-Bourgón, Javier, additional, Vernooij, Meike W., additional, Vieta, Eduard, additional, Vilarroya, Oscar, additional, Weickert, Cynthia, additional, Weickert, Thomas, additional, Westlye, Lars T., additional, Whalley, Heather, additional, Willinger, David, additional, Winter, Alexandra, additional, Wittfeld, Katharina, additional, Yang, Tony T., additional, Yoncheva, Yuliya, additional, Zijlmans, Jendé L., additional, Hoogman, Martine, additional, Franke, Barbara, additional, van Rooij, Daan, additional, Buitelaar, Jan, additional, Ching, Christopher R.K., additional, Andreassen, Ole A., additional, Pozzi, Elena, additional, Veltman, Dick, additional, Schmaal, Lianne, additional, van Erp, Theo G.M., additional, Turner, Jessica, additional, Castellanos, F. Xavier, additional, Pausova, Zdenka, additional, Thompson, Paul, additional, and Paus, Tomas, additional

Published
2022
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17. Fundamentos de psicobiología

Author

Redolar Ripoll, Diego, Boixadós i Anglès, Mercè, Moreno Alcázar, Ana, Portell Vidal, Mariona, Robles Muñoz, Noemí, Soriano Mas, Carles, Torras García, Meritxell, Vale Martínez, Anna M., Vives Brosa, Jaume

Published
2014

18. Virtual ontogeny of cortical growth preceding mental illness

Author

German Research Foundation, University of Münster, National Health and Medical Research Council (Australia), University of Cape Town, National Research Foundation (South Africa), Swinburne University of Technology, Jack Brockhoff Foundation, University of Melbourne, Barbara Dicker Brain Sciences Foundation, Rebecca L. Cooper Medical Research Foundation, Society for Mental Health Research (Australia), Swedish Research Council, Swedish Foundation for Strategic Research, Swedish Brain Foundation, Health Research Board (Ireland), Russian Foundation for Basic Research, University of Zurich, Pratt Foundation, Ramsay Health Care, Viertel Charitable Foundation, Schizophrenia Research Institute (Australia), European Commission, Australian Research Council, Instituto de Salud Carlos III, National Institute for Health and Care Research (US), National Institute for Health Research (UK), Ministry of Health of the Czech Republic, Bill & Melinda Gates Foundation, South African Medical Research Council, Carnegie Corporation of New York, Wellcome Trust, Medical Research Council (UK), Medical Research Scotland, Netherlands Organization for Scientific Research, Ambrogi, Sonia [0000-0002-2897-358X], Banaschewski, Tobias [0000-0003-4595-1144], Bandeira, Cibele Edom [0000-0003-0681-1309], Cupertino, Renata [0000-0002-3452-0632], Calderoni, Sara [0000-0002-6250-5739], Cannon, Dara [0000-0001-7378-3411], Carr, Vaughan [0000-0002-8907-5804], Chew, Qian Hui [0000-0003-0969-7994], Coghill, David [0000-0003-3017-9737], Cullen, Kathryn [0000-0001-9631-3770], Dahl, Andreas [0000-0002-8097-2082], Epstein, Jeffery [0000-0003-3464-5256], Foran, William [0000-0001-7491-9798], Fortea, Lydia [0000-0001-6778-2316], Fuentes-Claramonte, Paola [0000-0002-1428-7976], Fullerton, Janice M. [0000-0003-4014-4490], Furlong, Lisa [0000-0001-6196-4565], Gallagher, Louise [0000-0001-9462-2836], Gao, Si [0000-0002-4473-1142], Gotlib, Ian [0000-0002-3622-3199], Haavik, Jan [0000-0001-7865-2808], Henskens, Frans [0000-0003-2358-5630], Hilland, Eva [0000-0002-7102-8372], Hoekstra, Pieter J [0000-0001-7260-4119], Howells, Fleur M [0000-0001-9759-2556], Ipser, Jonathan [0000-0003-1272-0032], Jørgensen, Jes Kristian [0000-0001-9133-1670], Karantonis, James A. [0000-0003-2281-0912], Lawrie, Stephen [0000-0002-2444-5675], Patel, Yash, Shin, Jean, Abé, Christoph, Agartz, Ingrid, Alloza, Clara, Alnæs, Dag, Ambrogi, Sonia, Antonucci, Linda A., Arango, Celso, Arolt, Volker, Auzias, Guillaume, Gruber, Oliver, Haavik, Jan, McDonald, Colm, Hahn, Tim, Harrison, Ben J., Heindel, Walter, Henskens, Frans, Heslenfeld, Dirk J., Hilland, Eva, King, Joseph A., Vernooij, Meike W., Hoekstra, Pieter J., Hohmann, Sarah, Holz, Nathalie, Howells, Fleur M., McIntosh, Andrew, Ipser, Jonathan C., Meinert, Susanne, Hoogman, Martine, Kircher, Tilo, Kochunov, Peter, Vieta, Eduard, Koopowitz, Sheri-Michelle, Landén, Mikael, Landrø, Nils Inge, Lawrie, Stephen, Michie, Patricia T., Ayesa Arriola, Rosa, Mitchell, Philip, Moreno-Alcázar, Ana, Franke, Barbara, Mowry, Bryan, Bau, Claiton H. D., Muratori, Filippo, Nabulsi, Leila, Nenadić, Igor, O'Gorman Tuura, Ruth, Oosterlaan, Jaap, Overs, Bronwyn, Pantelis, Christos, Banaj, Nerisa, Parellada, Mara, van Rooij, Daan, Vilarroya, Oscar, Pariente, Jose C., Pauli, Paul, Pergola, Giulio, Piarulli, Francesco Maria, Picon, Felipe, Piras, Fabrizio, Pomarol-Clotet, Edith, Pretus, Clara, Quidé, Yann, Banaschewski, Tobias, Weickert, Cynthia, Buitelaar, Jan, Radua, Joaquim, Ramos-Quiroga, J. Antoni, Rasser, Paul E., Reif, Andreas, Retico, Alessandra, Roberts, Gloria, Rossell, Susan, Rovaris, Diego Luiz, Rubia, Katya, Weickert, Thomas, Sacchet, Matthew, Ching, Christopher R. K., Bandeira, Cibele, Salavert, Josep, Salvador, Raymond, Sarró, Salvador, Sawa, Akira, Schall, Ulrich, Scott, Rodney, Selvaggi, Pierluigi, Westlye, Lars T., Silk, Tim, Sim, Kang, Andreassen, Ole A., Skoch, Antonin, Başgöze, Zeynep, Spalletta, Gianfranco, Spaniel, Filip, Stein, Dan J., Steinsträter, Olaf, Stolicyn, Aleks, Whalley, Heather, Takayanagi, Yoichiro, Tamm, Leanne, Tavares, Maria, Pozzi, Elena, Teumer, Alexander, Thiel, Katharina, Cupertino, Renata Basso, Thomopoulos, Sophia I., Tomecek, David, Tomyshev, Alexander S., Willinger, David, Tordesillas-Gutiérrez, Diana, Tosetti, Michela, Uhlmann, Anne, Van Rheenen, Tamsyn, Veltman, Dick, Vázquez-Bourgon, Javier, Schmaal, Lianne, Jahanshad, Neda, Winter, Alexandra, Wittfeld, Katharina, Yang, Tony T., Yoncheva, Yuliya, Bauer, Jochen, Zijlmans, Jendé L., Baumeister, Sarah, Lebedeva, Irina, van Erp, Theo G. M., Turner, Jessica, Jakobi, Babette, Castellanos, F. Xavier, Pausova, Zdenka, Thompson, Paul, Paus, Tomas, Bernardoni, Fabio, Bertolino, Alessandro, Bonnin, Caterina Del Mar, Brandeis, Daniel, Luna, Beatriz, Brem, Silvia, Jansen, Andreas, Bruggemann, Jason, Bülow, Robin, Bustillo, Juan R., Calderoni, Sara, Calvo, Rosa, Canales-Rodríguez, Erick J., Cannon, Dara M., Carmona, Susanna, Carr, Vaughan J., Lundervold, Astri J., Janssen, Joost, Catts, Stanley V., Chenji, Sneha, Chew, Qian Hui, Coghill, David, Connolly, Colm G., Conzelmann, Annette, Craven, Alexander R., Crespo-Facorro, Benedicto, Cullen, Kathryn, Dahl, Andreas, Jonassen, Rune, MacMaster, Frank P., Dannlowski, Udo, Davey, Christopher G., Deruelle, Christine, Díaz-Caneja, Covadonga M., Dohm, Katharina, Ehrlich, Stefan, Epstein, Jeffery, Erwin-Grabner, Tracy, Eyler, Lisa T., Kaiser, Anna, Fedor, Jennifer, Maglanoc, Luigi A., Fitzgerald, Jacqueline, Foran, William, Ford, Judith M., Fortea, Lydia, Fuentes-Claramonte, Paola, Fullerton, Janice, Furlong, Lisa, Gallagher, Louise, Kaleda, Vasiliy, Gao, Bingchen, Gao, Si, Mathalon, Daniel H., Goikolea, Jose M., Gotlib, Ian, Goya-Maldonado, Roberto, Grabe, Hans J., Green, Melissa, Grevet, Eugenio H., Groenewold, Nynke A., Karantonis, James, Grotegerd, Dominik., German Research Foundation, University of Münster, National Health and Medical Research Council (Australia), University of Cape Town, National Research Foundation (South Africa), Swinburne University of Technology, Jack Brockhoff Foundation, University of Melbourne, Barbara Dicker Brain Sciences Foundation, Rebecca L. Cooper Medical Research Foundation, Society for Mental Health Research (Australia), Swedish Research Council, Swedish Foundation for Strategic Research, Swedish Brain Foundation, Health Research Board (Ireland), Russian Foundation for Basic Research, University of Zurich, Pratt Foundation, Ramsay Health Care, Viertel Charitable Foundation, Schizophrenia Research Institute (Australia), European Commission, Australian Research Council, Instituto de Salud Carlos III, National Institute for Health and Care Research (US), National Institute for Health Research (UK), Ministry of Health of the Czech Republic, Bill & Melinda Gates Foundation, South African Medical Research Council, Carnegie Corporation of New York, Wellcome Trust, Medical Research Council (UK), Medical Research Scotland, Netherlands Organization for Scientific Research, Ambrogi, Sonia [0000-0002-2897-358X], Banaschewski, Tobias [0000-0003-4595-1144], Bandeira, Cibele Edom [0000-0003-0681-1309], Cupertino, Renata [0000-0002-3452-0632], Calderoni, Sara [0000-0002-6250-5739], Cannon, Dara [0000-0001-7378-3411], Carr, Vaughan [0000-0002-8907-5804], Chew, Qian Hui [0000-0003-0969-7994], Coghill, David [0000-0003-3017-9737], Cullen, Kathryn [0000-0001-9631-3770], Dahl, Andreas [0000-0002-8097-2082], Epstein, Jeffery [0000-0003-3464-5256], Foran, William [0000-0001-7491-9798], Fortea, Lydia [0000-0001-6778-2316], Fuentes-Claramonte, Paola [0000-0002-1428-7976], Fullerton, Janice M. [0000-0003-4014-4490], Furlong, Lisa [0000-0001-6196-4565], Gallagher, Louise [0000-0001-9462-2836], Gao, Si [0000-0002-4473-1142], Gotlib, Ian [0000-0002-3622-3199], Haavik, Jan [0000-0001-7865-2808], Henskens, Frans [0000-0003-2358-5630], Hilland, Eva [0000-0002-7102-8372], Hoekstra, Pieter J [0000-0001-7260-4119], Howells, Fleur M [0000-0001-9759-2556], Ipser, Jonathan [0000-0003-1272-0032], Jørgensen, Jes Kristian [0000-0001-9133-1670], Karantonis, James A. [0000-0003-2281-0912], Lawrie, Stephen [0000-0002-2444-5675], Patel, Yash, Shin, Jean, Abé, Christoph, Agartz, Ingrid, Alloza, Clara, Alnæs, Dag, Ambrogi, Sonia, Antonucci, Linda A., Arango, Celso, Arolt, Volker, Auzias, Guillaume, Gruber, Oliver, Haavik, Jan, McDonald, Colm, Hahn, Tim, Harrison, Ben J., Heindel, Walter, Henskens, Frans, Heslenfeld, Dirk J., Hilland, Eva, King, Joseph A., Vernooij, Meike W., Hoekstra, Pieter J., Hohmann, Sarah, Holz, Nathalie, Howells, Fleur M., McIntosh, Andrew, Ipser, Jonathan C., Meinert, Susanne, Hoogman, Martine, Kircher, Tilo, Kochunov, Peter, Vieta, Eduard, Koopowitz, Sheri-Michelle, Landén, Mikael, Landrø, Nils Inge, Lawrie, Stephen, Michie, Patricia T., Ayesa Arriola, Rosa, Mitchell, Philip, Moreno-Alcázar, Ana, Franke, Barbara, Mowry, Bryan, Bau, Claiton H. D., Muratori, Filippo, Nabulsi, Leila, Nenadić, Igor, O'Gorman Tuura, Ruth, Oosterlaan, Jaap, Overs, Bronwyn, Pantelis, Christos, Banaj, Nerisa, Parellada, Mara, van Rooij, Daan, Vilarroya, Oscar, Pariente, Jose C., Pauli, Paul, Pergola, Giulio, Piarulli, Francesco Maria, Picon, Felipe, Piras, Fabrizio, Pomarol-Clotet, Edith, Pretus, Clara, Quidé, Yann, Banaschewski, Tobias, Weickert, Cynthia, Buitelaar, Jan, Radua, Joaquim, Ramos-Quiroga, J. Antoni, Rasser, Paul E., Reif, Andreas, Retico, Alessandra, Roberts, Gloria, Rossell, Susan, Rovaris, Diego Luiz, Rubia, Katya, Weickert, Thomas, Sacchet, Matthew, Ching, Christopher R. K., Bandeira, Cibele, Salavert, Josep, Salvador, Raymond, Sarró, Salvador, Sawa, Akira, Schall, Ulrich, Scott, Rodney, Selvaggi, Pierluigi, Westlye, Lars T., Silk, Tim, Sim, Kang, Andreassen, Ole A., Skoch, Antonin, Başgöze, Zeynep, Spalletta, Gianfranco, Spaniel, Filip, Stein, Dan J., Steinsträter, Olaf, Stolicyn, Aleks, Whalley, Heather, Takayanagi, Yoichiro, Tamm, Leanne, Tavares, Maria, Pozzi, Elena, Teumer, Alexander, Thiel, Katharina, Cupertino, Renata Basso, Thomopoulos, Sophia I., Tomecek, David, Tomyshev, Alexander S., Willinger, David, Tordesillas-Gutiérrez, Diana, Tosetti, Michela, Uhlmann, Anne, Van Rheenen, Tamsyn, Veltman, Dick, Vázquez-Bourgon, Javier, Schmaal, Lianne, Jahanshad, Neda, Winter, Alexandra, Wittfeld, Katharina, Yang, Tony T., Yoncheva, Yuliya, Bauer, Jochen, Zijlmans, Jendé L., Baumeister, Sarah, Lebedeva, Irina, van Erp, Theo G. M., Turner, Jessica, Jakobi, Babette, Castellanos, F. Xavier, Pausova, Zdenka, Thompson, Paul, Paus, Tomas, Bernardoni, Fabio, Bertolino, Alessandro, Bonnin, Caterina Del Mar, Brandeis, Daniel, Luna, Beatriz, Brem, Silvia, Jansen, Andreas, Bruggemann, Jason, Bülow, Robin, Bustillo, Juan R., Calderoni, Sara, Calvo, Rosa, Canales-Rodríguez, Erick J., Cannon, Dara M., Carmona, Susanna, Carr, Vaughan J., Lundervold, Astri J., Janssen, Joost, Catts, Stanley V., Chenji, Sneha, Chew, Qian Hui, Coghill, David, Connolly, Colm G., Conzelmann, Annette, Craven, Alexander R., Crespo-Facorro, Benedicto, Cullen, Kathryn, Dahl, Andreas, Jonassen, Rune, MacMaster, Frank P., Dannlowski, Udo, Davey, Christopher G., Deruelle, Christine, Díaz-Caneja, Covadonga M., Dohm, Katharina, Ehrlich, Stefan, Epstein, Jeffery, Erwin-Grabner, Tracy, Eyler, Lisa T., Kaiser, Anna, Fedor, Jennifer, Maglanoc, Luigi A., Fitzgerald, Jacqueline, Foran, William, Ford, Judith M., Fortea, Lydia, Fuentes-Claramonte, Paola, Fullerton, Janice, Furlong, Lisa, Gallagher, Louise, Kaleda, Vasiliy, Gao, Bingchen, Gao, Si, Mathalon, Daniel H., Goikolea, Jose M., Gotlib, Ian, Goya-Maldonado, Roberto, Grabe, Hans J., Green, Melissa, Grevet, Eugenio H., Groenewold, Nynke A., Karantonis, James, and Grotegerd, Dominik.

Abstract

[Background]: Morphology of the human cerebral cortex differs across psychiatric disorders, with neurobiology and developmental origins mostly undetermined. Deviations in the tangential growth of the cerebral cortex during pre/perinatal periods may be reflected in individual variations in cortical surface area later in life., [Methods]: Interregional profiles of group differences in surface area between cases and controls were generated using T1-weighted magnetic resonance imaging from 27,359 individuals including those with attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depressive disorder, schizophrenia, and high general psychopathology (through the Child Behavior Checklist). Similarity of interregional profiles of group differences in surface area and prenatal cell-specific gene expression was assessed., [Results]: Across the 11 cortical regions, group differences in cortical area for attention-deficit/hyperactivity disorder, schizophrenia, and Child Behavior Checklist were dominant in multimodal association cortices. The same interregional profiles were also associated with interregional profiles of (prenatal) gene expression specific to proliferative cells, namely radial glia and intermediate progenitor cells (greater expression, larger difference), as well as differentiated cells, namely excitatory neurons and endothelial and mural cells (greater expression, smaller difference). Finally, these cell types were implicated in known pre/perinatal risk factors for psychosis. Genes coexpressed with radial glia were enriched with genes implicated in congenital abnormalities, birth weight, hypoxia, and starvation. Genes coexpressed with endothelial and mural genes were enriched with genes associated with maternal hypertension and preterm birth., [Conclusions]: Our findings support a neurodevelopmental model of vulnerability to mental illness whereby prenatal risk factors acting through cell-specific processes lead to deviations from typical brain development during pregnancy.

Published
2022

19. Mental Health Promotion and Intervention in Occupational Settings: Protocol for a Pilot Study of the MENTUPP Intervention

Author

Arensman, Ella, primary, O’Connor, Cliodhna, additional, Leduc, Caleb, additional, Griffin, Eve, additional, Cully, Grace, additional, Ní Dhálaigh, Doireann, additional, Holland, Carolyn, additional, Van Audenhove, Chantal, additional, Coppens, Evelien, additional, Tsantila, Fotini, additional, Ross, Victoria, additional, Aust, Birgit, additional, Pashoja, Arlinda Cerga, additional, Cresswell-Smith, Johanna, additional, Cox, Laura, additional, de Winter, Lars, additional, Fanaj, Naim, additional, Greiner, Birgit A., additional, Hegerl, Ulrich, additional, Mathieu, Sharna, additional, Moreno-Alcázar, Ana, additional, Orchard, Wendy, additional, Paterson, Charlotte, additional, Purebl, György, additional, Qirjako, Gentiana, additional, Reich, Hanna, additional, and Corcoran, Paul, additional

Published
2022
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20. A Multisite, Randomized Controlled Clinical Trial of Computerized Cognitive Remediation Therapy for Schizophrenia

Author

Gomar, Jesús J., Valls, Elia, Radua, Joaquim, Mareca, Celia, Tristany, Josep, del Olmo, Francisco, Rebolleda-Gil, Carlos, Jañez-Álvarez, María, de Álvaro, Francisco J., Ovejero, María R., Llorente, Ana, Teixidó, Cristina, Donaire, Ana M., García-Laredo, Eduardo, Lazcanoiturburu, Andrea, Granell, Luis, Mozo, Cristina de Pablo, Pérez-Hernández, Mónica, Moreno-Alcázar, Ana, Pomarol-Clotet, Edith, and McKenna, Peter J.

Published
2015
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21. Workplace interventions to reduce depression and anxiety in small and medium-sized enterprises: A systematic review

Author

Hogg, Bridget, primary, Medina, Joan Carles, additional, Gardoki-Souto, Itxaso, additional, Serbanescu, Ilinca, additional, Moreno-Alcázar, Ana, additional, Cerga-Pashoja, Arlinda, additional, Coppens, Evelien, additional, Tóth, Mónika Ditta, additional, Fanaj, Naim, additional, Greiner, Birgit A., additional, Holland, Carolyn, additional, Kõlves, Kairi, additional, Maxwell, Margaret, additional, Qirjako, Gentiana, additional, de Winter, Lars, additional, Hegerl, Ulrich, additional, Pérez-Sola, Victor, additional, Arensman, Ella, additional, and Amann, Benedikt L., additional

Published
2021
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22. Clinical Features, Neuropsychology and Neuroimaging in Bipolar and Borderline Personality Disorder: A Systematic Review of Cross-Diagnostic Studies

Author

Massó Rodriguez, Anna, primary, Hogg, Bridget, additional, Gardoki-Souto, Itxaso, additional, Valiente-Gómez, Alicia, additional, Trabsa, Amira, additional, Mosquera, Dolores, additional, García-Estela, Aitana, additional, Colom, Francesc, additional, Pérez, Victor, additional, Padberg, Frank, additional, Moreno-Alcázar, Ana, additional, and Amann, Benedikt Lorenz, additional

Published
2021
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23. Workplace interventions to reduce depression and anxiety in small and medium-sized enterprises: A systematic review

Author

Hogg, Bridget M., Medina Alcaraz, Juan Carlos, Gardoki Souto, Itxaso, Serbanescu, Ilinca, Moreno Alcázar, Ana, Cerga Pashoja, Arlinda, Coppens, Evalien, Tóth, Mónika Ditta, Fanaj, Naim, Greiner, Birgit A., Holland, Carolyn, Kolves, Kairi, Maxwell, Margaret, Qirjako, Gentiana, Winter, Lars de, Hegerl, Ulrich, Pérez Sola, Victor, Arensman, Ella, Amann, Benedikt Lorenz, Universitat Oberta de Catalunya (UOC), Universitat Autònoma de Barcelona, and Universitat de Barcelona

Subjects
Suicide, Depression, Small- and medium-sized enterprises, Anxiety, Psychosocial
Abstract

Background: Depression and anxiety are the most prevalent mental health difficulties in the workplace, costing the global economy $1 trillion each year. Evidence indicates that symptoms may be reduced by interventions in the workplace. This paper is the first to systematically review psychosocial interventions for depression, anxiety, and suicidal ideation and behaviours in small-to medium-size enterprises (SMEs). Methods: A systematic search following PRISMA guidelines, registered in PROSPERO (CRD42020156275), was conducted for psychosocial interventions targeting depression, anxiety, and suicidal ideation/behaviour in SMEs. The PubMed, PsycINFO, Scopus, and two specific occupational health databases were searched, as well as four databases for grey literature, without time limit until 2nd December 2019. Results: In total, 1283 records were identified, 70 were retained for full-text screening, and seven met the inclusion criteria: three randomised controlled trials (RCTs), three before and after designs and one non-randomised trial, comprising 5111 participants. Study quality was low to moderate according to the Quality Assessment Tool for Quantitative Studies. Five studies showed a reduction in depression and anxiety symptoms using techniques based on cognitive behavioural therapy (CBT), two reported no significant change. Limitations: Low number and high heterogeneity of interventions and outcomes, high attrition and lack of rigorous RCTs. Conclusions: Preliminary evidence indicates CBT-based interventions can be effective in targeting symptoms of depression and anxiety in SME employees. There may be unique challenges to implementing programmes in SMEs. Further research is needed in this important area.

Published
2021

24. Clinical Features, Neuropsychology and Neuroimaging in Bipolar and Borderline Personality Disorder : A Systematic Review of Cross-Diagnostic Studies

Author

Massó Rodriguez, Anna, Hogg, Bridget, Gardoki-Souto, Itxaso, Valiente-Gómez, Alicia, Trabsa, Amira, Mosquera, Dolores, García-Estela, Aitana, Colom, Francesc, Pérez, Victor, Padberg, Frank, Moreno-Alcázar, Ana, Amann, Benedikt Lorenz, Massó Rodriguez, Anna, Hogg, Bridget, Gardoki-Souto, Itxaso, Valiente-Gómez, Alicia, Trabsa, Amira, Mosquera, Dolores, García-Estela, Aitana, Colom, Francesc, Pérez, Victor, Padberg, Frank, Moreno-Alcázar, Ana, and Amann, Benedikt Lorenz

Abstract

Background: Bipolar Disorder (BD) and Borderline Personality Disorder (BPD) have clinically been evolving as separate disorders, though there is still debate on the nosological valence of both conditions, their interaction in terms of co-morbidity or disorder spectrum and their distinct pathophysiology. Objective: The objective of this review is to summarize evidence regarding clinical features, neuropsychological performance and neuroimaging findings from cross-diagnostic studies comparing BD and BPD, to further caracterize their complex interplay. Methods: Using PubMed, PsycINFO and TripDataBase, we conducted a systematic literature search based on PRISMA guidelines of studies published from January 1980 to September 2019 which directly compared BD and BPD. Results: A total of 28 studies comparing BD and BPD were included: 19 compared clinical features, 6 neuropsychological performance and three neuroimaging abnormalities. Depressive symptoms have an earlier onset in BPD than BD. BD patients present more mixed or manic symptoms, with BD-I differing from BPD in manic phases. BPD patients show more negative attitudes toward others and self, more conflictive interpersonal relationships, and more maladaptive regulation strategies in affective instability with separate pathways. Impulsivity seems more a trait in BPD rather than a state as in BD. Otherwise, BD and BPD overlap in depressive and anxious symptoms, dysphoria, various abnormal temperamental traits, suicidal ideation, and childhood trauma. Both disorders differ and share deficits in neuropsychological and neuroimaging findings. Conclusion: Clinical data provide evidence of overlapping features in both disorders, with most of those shared symptoms being more persistent and intense in BPD. Thus, categorical classifications should be compared to dimensional approaches in transdiagnostic studies investigating BPD features in BD regarding their respective explanatory power for individual trajectories. Systematic R

Published
2021

25. Workplace interventions to reduce depression and anxiety in small and medium-sized enterprises: a systematic review

Author

Hogg, Bridget, Medina, Joan Carles, Gardoki-Souto, Itxaso, Serbanescu, Ilinca, Moreno-Alcázar, Ana, Cerga Pashoja, Arlinda, Coppens, Evelien, Tóth, Mónika Ditta, Fanaj, Naim, Greiner, Birgit, Holland, Carolyn, Kõlves, Kairi, Maxwell, Margaret, Qirjako, Gentiana, De Winter, Lars, Hegerl, Ulrich, Pérez-Sola, Victor, Arensman, Ella, Amann, Benedikt Lorenz, Hogg, Bridget, Medina, Joan Carles, Gardoki-Souto, Itxaso, Serbanescu, Ilinca, Moreno-Alcázar, Ana, Cerga Pashoja, Arlinda, Coppens, Evelien, Tóth, Mónika Ditta, Fanaj, Naim, Greiner, Birgit, Holland, Carolyn, Kõlves, Kairi, Maxwell, Margaret, Qirjako, Gentiana, De Winter, Lars, Hegerl, Ulrich, Pérez-Sola, Victor, Arensman, Ella, and Amann, Benedikt Lorenz

Abstract

Background: Depression and anxiety are the most prevalent mental health difficulties in the workplace, costing the global economy $1 trillion each year. Evidence indicates that symptoms may be reduced by interventions in the workplace. This paper is the first to systematically review psychosocial interventions for depression, anxiety, and suicidal ideation and behaviours in small-to medium-size enterprises (SMEs). Methods: A systematic search following PRISMA guidelines, registered in PROSPERO (CRD42020156275), was conducted for psychosocial interventions targeting depression, anxiety, and suicidal ideation/behaviour in SMEs. The PubMed, PsycINFO, Scopus, and two specific occupational health databases were searched, as well as four databases for grey literature, without time limit until 2nd December 2019. Results: In total, 1283 records were identified, 70 were retained for full-text screening, and seven met the inclusion criteria: three randomised controlled trials (RCTs), three before and after designs and one non-randomised trial, comprising 5111 participants. Study quality was low to moderate according to the Quality Assessment Tool for Quantitative Studies. Five studies showed a reduction in depression and anxiety symptoms using techniques based on cognitive behavioural therapy (CBT), two reported no significant change. Limitations: Low number and high heterogeneity of interventions and outcomes, high attrition and lack of rigorous RCTs. Conclusions: Preliminary evidence indicates CBT-based interventions can be effective in targeting symptoms of depression and anxiety in SME employees. There may be unique challenges to implementing programmes in SMEs. Further research is needed in this important area.

Published
2021

26. Traumatic events in dual disorders : prevalence and clinical characteristics

Author

Blanco Presas, Laura, Sió, Albert, Hogg, Bridget, Esteve-Puig, R, Radua, Joaquim, Solanes, Aleix, Gardoki-Souto, Itxaso, Sauras, Rosa, Farré, Adriana, Castillo, Claudio, Valiente-Gómez, Alicia, Pérez, Víctor, Torrens, Marta, Amann, Benedikt L., Moreno Alcázar, Ana, and Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal

Subjects
Pediatrics, medicine.medical_specialty, medicine.drug_class, Population, prevalence, Prevalence, lcsh:Medicine, Dissociative, Article, 03 medical and health sciences, 0302 clinical medicine, psychological trauma, posttraumatic stress disorder, substance use disorders, dual diagnosis, Psychological trauma, Medicine, Dual diagnosis, Risk factor, education, Adverse effect, Substance use disorders, education.field_of_study, business.industry, lcsh:R, Posttraumatic stress disorder, General Medicine, medicine.disease, 030227 psychiatry, Etiology, business, 030217 neurology & neurosurgery
Abstract

Psychological trauma has been identified in substance use disorders (SUD) as a major etiological risk factor. However, detailed and systematic data about the prevalence and types of psychological trauma in dual disorders have been scarce to date. In this study, 150 inpatients were recruited and cross-sectionally screened on their substance use severity, psychological trauma symptoms, comorbidities, and clinical severity. One hundred patients fulfilled criteria for a dual disorder, while 50 patients were diagnosed with only SUD. Ninety-four percent of the whole sample suffered from at least one lifetime traumatic event. The prevalence rates of Posttraumatic Stress Disorder diagnosis for dual disorder and only SUD was around 20% in both groups; however, patients with dual disorder presented more adverse events, more childhood trauma, more dissociative symptoms, and a more severe clinical profile than patients with only SUD. Childhood maltreatment can also serve as a predictor for developing a dual disorder diagnosis and as a risk factor for developing a more complex and severe clinical profile. These data challenge our current clinical practice in the treatment of patients suffering from dual disorder or only SUD diagnosis and favor the incorporation of an additional trauma-focused therapy in this population. This may improve the prognosis and the course of the illness in these patients.

Published
2020

27. EMDR Versus Treatment-as-Usual in Patients With Chronic Non-Malignant Pain: A Randomized Controlled Pilot Study

Author

Suárez, Nieves Arias, primary, Pérez, Joana Moreno, additional, Redolar-Ripoll, Diego, additional, Hogg, Bridget M., additional, Gardoki-Souto, Itxaso, additional, Guerrero, Francisca García, additional, Cabrera, Sandra Jaime, additional, Bernal, Daniel Samper, additional, Amann, Benedikt L., additional, and Moreno-Alcázar, Ana, additional

Published
2020
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28. The Current Status of EMDR Therapy, Specific Target Areas, and Goals for the Future

Author

Matthijssen, Suzy J. M. A., primary, Lee, Christopher W., additional, de Roos, Carlijn, additional, Barron, Ian G., additional, Jarero, Ignacio, additional, Shapiro, Elan, additional, Hurley, E. C., additional, Schubert, Sarah J., additional, Baptist, Joyce, additional, Amann, Benedikt L., additional, Moreno-Alcázar, Ana, additional, Tesarz, Jonas, additional, and de Jongh, Ad, additional

Published
2020
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29. Traumatic Events in Dual Disorders: Prevalence and Clinical Characteristics

Author

Blanco, Laura, primary, Sió, Albert, additional, Hogg, Bridget, additional, Esteve, Ricard, additional, Radua, Joaquim, additional, Solanes, Aleix, additional, Gardoki-Souto, Itxaso, additional, Sauras, Rosa, additional, Farré, Adriana, additional, Castillo, Claudio, additional, Valiente-Gómez, Alicia, additional, Pérez, Víctor, additional, Torrens, Marta, additional, Amann, Benedikt L., additional, and Moreno-Alcázar, Ana, additional

Published
2020
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30. Shared and differential default-mode related patterns of activity in an autobiographical, a self-referential and an attentional task

Author

Fuentes-Claramonte, Paola, Martín-Subero, Marta, Salgado-Pineda, Pilar, Alonso-Lana, Silvia, Moreno Alcázar, Ana, Argila-Plaza, Isabel, Santo-Angles, Aniol, Albajes-Eizagirre, Anton, Anguera-Camós, Maria, Capdevila, Antoni, Sarró, Salvador, McKenna, Peter J., Pomarol-Clotet, Edith, Salvador, Raymond, and Universitat Autònoma de Barcelona

Subjects
Male, Self-Assessment, Social Sciences, Hippocampus, Task (project management), Cognition, Learning and Memory, 0302 clinical medicine, Neural Pathways, Task Performance and Analysis, Medicine and Health Sciences, Psychology, Attention, Cervell, Prefrontal cortex, Default mode network, Cerebral Cortex, Brain Mapping, Multidisciplinary, 05 social sciences, Brain, Middle Aged, Magnetic Resonance Imaging, Temporal Lobe, Memory, Short-Term, Memory Recall, Medicine, Female, Anatomy, Research Article, Cognitive psychology, Adult, Adolescent, Science, Memory, Episodic, Prefrontal Cortex, 050105 experimental psychology, 03 medical and health sciences, Young Adult, Memory, Humans, 0501 psychology and cognitive sciences, Set (psychology), Aged, Cingulate Cortex, Recall, Autobiographical memory, Working memory, Cognitive Psychology, Biology and Life Sciences, Mental Recall, Cognitive Science, Nerve Net, 030217 neurology & neurosurgery, Neuroscience, Memòria
Abstract

The default-mode network (DMN) comprises a set of brain regions that show deactivations during performance of attentionally demanding tasks, but also activation during certain processes including recall of autobiographical memories and processing information about oneself, among others. However, the DMN is not activated in a homogeneous manner during performance of such tasks, so it is not clear to what extent its activation patterns correspond to deactivation patterns seen during attention-demanding tasks. In this fMRI study we compared patterns of activation in response to an autobiographical memory task to those observed in a self/other-reflection task, and compared both to deactivations observed during the n-back working memory task. Autobiographical recall and self-reflection activated several common DMN areas, which were also deactivated below baseline levels by the n-back task. Activation in the medial temporal lobe was seen during autobiographical recall but not the self/other task, and right angular gyrus activity was specifically linked to other-reflection. ROI analysis showed that most, but not all DMN regions were activated above baseline levels during the autobiographical memory and self-reflection tasks. Our results provide evidence for the usefulness of the autobiographical memory task to study DMN activity and support the notion of interacting subsystems within this network.

Published
2019

32. A Multicenter Phase II Rater-Blinded Randomized Controlled Trial to Compare the Effectiveness of Eye Movement Desensitization Reprocessing Therapy vs. Treatment as Usual in Patients With Substance Use Disorder and History of Psychological Trauma: A Study Design and Protocol

Author

Valiente-Gómez, Alicia, primary, Moreno-Alcázar, Ana, additional, Radua, Joaquim, additional, Hogg, Bridget, additional, Blanco, Laura, additional, Lupo, W., additional, Pérez, Víctor, additional, Robles-Martínez, Maria, additional, Torrens, Marta, additional, and Amann, Benedikt L., additional

Published
2019
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34. Additional file 1: of Eye movement desensitization and reprocessing therapy versus supportive therapy in affective relapse prevention in bipolar patients with a history of trauma: study protocol for a randomized controlled trial

Author

Moreno-Alcázar, Ana, Radua, Joaquim, Landín-Romero, Ramon, Blanco, Laura, Madre, Mercè, Reinares, Maria, Comes, Mercè, Jiménez, Esther, Crespo, Jose, Vieta, Eduard, Pérez, Victor, Novo, Patricia, Doñate, Marta, Cortizo, Romina, Valiente-Gómez, Alicia, Lupo, Walter, McKenna, Peter, Pomarol-Clotet, Edith, and Amann, Benedikt

Abstract

SPIRIT flow diagram. (PDF 83 kb)

Published
2017
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35. Additional file 2: of Eye movement desensitization and reprocessing therapy versus supportive therapy in affective relapse prevention in bipolar patients with a history of trauma: study protocol for a randomized controlled trial

Author

Moreno-Alcázar, Ana, Radua, Joaquim, Landín-Romero, Ramon, Blanco, Laura, Madre, Mercè, Reinares, Maria, Comes, Mercè, Jiménez, Esther, Crespo, Jose, Vieta, Eduard, Pérez, Victor, Novo, Patricia, Doñate, Marta, Cortizo, Romina, Valiente-Gómez, Alicia, Lupo, Walter, McKenna, Peter, Pomarol-Clotet, Edith, and Amann, Benedikt

Abstract

SPIRIT Checklist. (DOC 122 kb)

Published
2017
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36. A Multicenter Phase II RCT to Compare the Effectiveness of EMDR Versus TAU in Patients With a First-Episode Psychosis and Psychological Trauma: A Protocol Design.

Author

Valiente-Gómez, Alicia, Pujol, Nuria, Moreno-Alcázar, Ana, Radua, Joaquim, Monteagudo-Gimeno, Eila, Gardoki-Souto, Itxaso, Hogg, Bridget, Álvarez, Maria José, Safont, Gemma, Lupo, Walter, Pérez, Victor, Amann, Benedikt L., Alayón, Rebeca, Coll, Montserrat, Eslava, Jairo Santiago García, Pérez Sánchez, Ezequiel, Llimona, Carla, Macias, Cristina, Mané, Anna, and Marín, Lorena

Subjects
CLINICAL trial registries, POST-traumatic stress, PSYCHOSES, EMOTIONAL trauma
Abstract

Background: Patients with a first episode psychosis (FEP) who are admitted for the first time to a psychiatric hospital frequently have experienced prior psychological trauma. Additionally, 40–80% develop posttraumatic stress symptoms, which are summarized as a post-psychotic post-traumatic syndrome (PPS). Eye Movement Desensitization and reprocessing (EMDR) therapy could be an effective psychotherapy to treat a PPS and prior psychological traumas in this population. Objectives: To assess if EMDR therapy leads to: 1) a reduction of relapses after intervention, 2) an improvement of trauma-related, psychotic and affective symptoms, 3) an improvement of overall functioning, and 4) an improvement in quality of life. Methods: This is a multicenter phase II rater-blinded randomized controlled trial in which 80 FEP patients with a history of psychological trauma will be randomly assigned to EMDR (n = 40) or to TAU (n = 40). Traumatic events will be measured by the Global Assessment of Posttraumatic Stress Questionnaire, the Cumulative Trauma Screening, the Impact of Event Scale-Revised, the Dissociative Experiences Scale, the Childhood Trauma Scale, the Holmes–Rahe Life Stress Inventory, and the Dissociative Experiences Questionnaire. Clinical symptomatology will be evaluated using the Suicide and Drug Consumption module of the International Neuropsychiatric Interview, Structured Clinical Interview for Positive and Negative Syndrome Scale, Young's Scale for Mania Evaluation, and Beck Depression II Questionnaire. Functionality will be assessed with the Global Assessment of Functioning and the Quality of Life with the Standardized Instrument developed by the EuroQol Group. The cognitive insight and adherence to the treatment will be assessed with the Beck Cognitive Insight Scale and the Drug Attitude Inventory. All variables will be measured at baseline, post-treatment and at 12-month follow-up. Conclusion: This study will provide evidence of whether EMDR therapy is effective in reducing trauma and clinical symptoms, reducing relapses and in improving functionality and quality of life in patients with FEP and a history of trauma. Clinical Trial Registration: www.ClinicalTrials.gov , identifier: NCT03991377 [ABSTRACT FROM AUTHOR]

Published
2020
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37. Larger Gray Matter Volume in the Basal Ganglia of Heavy Cannabis Users Detected by Voxel-Based Morphometry and Subcortical Volumetric Analysis

Author

Moreno-Alcázar, Ana, primary, Gonzalvo, Begoña, additional, Canales-Rodríguez, Erick J., additional, Blanco, Laura, additional, Bachiller, Diana, additional, Romaguera, Anna, additional, Monté-Rubio, Gemma C., additional, Roncero, Carlos, additional, McKenna, Peter J., additional, and Pomarol-Clotet, Edith, additional

Published
2018
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40. Eye movement desensitization and reprocessing therapy versus supportive therapy in affective relapse prevention in bipolar patients with a history of trauma: study protocol for a randomized controlled trial

Author

Moreno-Alcázar, Ana, primary, Radua, Joaquim, additional, Landín-Romero, Ramon, additional, Blanco, Laura, additional, Madre, Mercè, additional, Reinares, Maria, additional, Comes, Mercè, additional, Jiménez, Esther, additional, Crespo, Jose Manuel, additional, Vieta, Eduard, additional, Pérez, Victor, additional, Novo, Patricia, additional, Doñate, Marta, additional, Cortizo, Romina, additional, Valiente-Gómez, Alicia, additional, Lupo, Walter, additional, McKenna, Peter J., additional, Pomarol-Clotet, Edith, additional, and Amann, Benedikt L., additional

Published
2017
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44. Alteraciones neuroanatómicas en los núcleos caudado y accumbens como marcador neurobiológico de mala respuesta al metilfenidato en el tdah infantil

Author

Moreno Alcázar, Ana, Vilarroya Oliver, Óscar, and Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal

Subjects
Resonancia magnética, 616.89, TDAH, Metilfenidato, Ciències de la Salut
Abstract

El Trastorno por Déficit de Atención con Hiperactividad (TDAH) es uno de los trastornos del neurodesarrollo más comunes que se inicia en la edad temprana y que se caracteriza por presentar un cuadro clínico de inatención, hiperactividad e impulsividad. Desde un punto de vista farmacológico, el metilfenidato (MFD) es el fármaco de primera elección para tratar el TDAH debido a la alta eficacia que presenta a la hora de mejorar los síntomas, no obstante, se ha estimado que un 30% de estos pacientes no responden de manera adecuada. Actualmente no se disponen de marcadores clínicos, genéticos o neurobiológicos que permitan identificar a los pacientes susceptibles de presentar una buena o mala respuesta al MFD. El objetivo del presente estudio ha sido identificar a través de técnicas de resonancia magnética (RM) y variables clínicas y neuropsicológicas si existen diferencias cerebrales y/o clínico-cognitivas entre los pacientes que presentan una respuesta favorable o desfavorable al MFD. Para ello, se ha utilizado un diseño ex post facto de casos y controles para estudiar una muestra de 27 pacientes TDAH (de entre 6 y 15 años de edad) naïve al tratamiento con MFD. La evaluación clínica de los pacientes al mes de iniciar el tratamiento farmacológico ha indicado que 16 sujetos han presentado una respuesta favorable y 11 desfavorable. Los resultados de RM han mostrado que los pacientes con una buena respuesta al MFD tienen una mayor concentración de sustancia gris en la cabeza de ambos núcleos caudados y en el núcleo accumbens derecho respecto a los pacientes que no responden de manera adecuada. En relación a las variables clínicas y neuropsicológicas, no se han encontrado diferencias entre los dos grupos antes de iniciar el tratamiento farmacológico, sin embargo sí se han hallado en la evaluación post-tratamiento en el cuestionario de Conners para padres y el test Continuous Performance Test. Asimismo, se ha encontrado una relación entre estas dos medidas y los volúmenes del núcleo caudado y accumbens de manera bilateral. Estos resultados no sólo apoyan la hipótesis sobre la implicación de estas estructuras en la fisiopatología del TDAH, sino que también ponen de manifiesto su implicación en la respuesta al tratamiento farmacológico y su relación con los síntomas tanto cognitivos como conductuales que se manifiestan en los pacientes con TDAH. Los resultados derivados de este trabajo podrían ser de gran utilidad para determinar un fenotipo neuroanatómico que permita diferenciar a los pacientes que presentarán una respuesta favorable o desfavorable al MFD en el momento del diagnóstico y predecir su grado de mejoría a nivel clínico y neuropsicológico, Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders occurring in childhood. The main symptoms are developmentally excessive levels of inattention, impulsivity and hyperactivity. Methylphenidate (MPH) is the drug of first choice for treating ADHD because of its high efficacy to reduce the symptoms. It has been estimated that 30% of patients with ADHD do not respond adequately to MPH. Presently, there are no clinical or biological markers distinguishing good and bad responders. The aim of this study was to evaluate whether anatomical and/or clinical/cognitive differences exist between these two types of patients (good and bad responders) by applying magnetic resonance (MR) procedures and clinical and neuropsychological assessments. A case-control study was implemented to analyze a sample of twenty-seven treatment-naïve patients with ADHD (between six and fifteen years old). MPH administration started one day after the MR acquisition. After a month, psychiatrists established the good or poor response to MPH according to clinical criteria. Sixteen patients showed good response to the MPH and eleven did a poor one. The results has showed the good responders had a higher concentration of gray matter in the both Caudate nucleus head and the right Accumbens nucleus than the bad responders. Before MPH treatment it has no found differences between groups regarding clinical and neuropsychological measures. However, statistical differences has found in the Conners' Parent Rating Scales (CPRS) and Continuous Performance Test (CPT) after treatment. Furthermore, a significant correlation has found between Caudate and Accumbens nuclei volume (bilaterally) and the CPRS and CPT improvement. These results support the hypothesis of the involvement of the Caudate and Accumbens nuclei in MPH response and in physiopathology of ADHD. Also, such findings could also be useful to determinate a neuroanatomical phenotype as an eventual sign that helps in characterizing, at the time of diagnosis, patients with good and bad response to MPH and predicting the clinical and neuropsychological improvement level.

Published
2012

45. Functional Imaging Changes in the Medial Prefrontal Cortex in Adult ADHD

Author

Salavert, José, primary, Ramos-Quiroga, Josep A., additional, Moreno-Alcázar, Ana, additional, Caseras, Xavier, additional, Palomar, Gloria, additional, Radua, Joaquim, additional, Bosch, Rosa, additional, Salvador, Raymond, additional, McKenna, Peter J., additional, Casas, Miquel, additional, and Pomarol-Clotet, Edith, additional

Published
2015
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46. Surface-based brain morphometry and diffusion tensor imaging in schizoaffective disorder.

Author

Landin-Romero, Ramón, Canales-Rodríguez, Erick J., Kumfor, Fiona, Moreno-Alcázar, Ana, Madre, Mercè, Maristany, Teresa, Pomarol-Clotet, Edith, and Amann, Benedikt L.

Subjects
BRAIN anatomy, COMPARATIVE studies, STATISTICAL correlation, INTELLIGENCE tests, INTERVIEWING, LONGITUDINAL method, MAGNETIC resonance imaging, CLASSIFICATION of mental disorders, NEURORADIOLOGY, PROBABILITY theory, RESEARCH funding, SCHIZOAFFECTIVE disorders, T-test (Statistics), DESCRIPTIVE statistics, GRAY matter (Nerve tissue)
Abstract

Background: The profile of grey matter abnormalities and related white-matter pathology in schizoaffective disorder has only been studied to a limited extent. The aim of this study was to identify grey- and white-matter abnormalities in patients with schizoaffective disorder using complementary structural imaging techniques. Methods: Forty-five patients meeting Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition criteria and Research Diagnostic Criteria for schizoaffective disorder and 45 matched healthy controls underwent structural-T1 and diffusion magnetic resonance imaging to enable surface-based brain morphometry and diffusion tensor imaging analyses. Analyses were conducted to determine group differences in cortical volume, cortical thickness and surface area, as well as in fractional anisotropy and mean diffusivity. Results: At a threshold of p = 0.05 corrected, all measures revealed significant differences between patients and controls at the group level. Spatial overlap of abnormalities was observed across the various structural neuroimaging measures. In grey matter, patients with schizoaffective disorder showed abnormalities in the frontal and temporal lobes, striatum, fusiform, cuneus, precuneus, lingual and limbic regions. White-matter abnormalities were identified in tracts connecting these areas, including the corpus callosum, superior and inferior longitudinal fasciculi, anterior thalamic radiation, uncinate fasciculus and cingulum bundle. Conclusion: The spatial overlap of abnormalities across the different imaging techniques suggests widespread and consistent brain pathology in schizoaffective disorder. The abnormalities were mainly detected in areas that have commonly been reported to be abnormal in schizophrenia, and to some extent in bipolar disorder, which may explain the clinical and aetiological overlap in these disorders. [ABSTRACT FROM AUTHOR]

Published
2017
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48. Corrigendum: A Multicenter Phase II RCT to Compare the Effectiveness of EMDR Versus TAU in Patients With a First-Episode Psychosis and Psychological Trauma: A Protocol Design.

Author

Valiente-Gómez, Alicia, Pujol, Nuria, Moreno-Alcázar, Ana, Radua, Joaquim, Monteagudo-Gimeno, Eila, Gardoki-Souto, Itxaso, Hogg, Bridget, Álvarez, Maria José, Safont, Gemma, Lupo, Walter, Pérez, Victor, Amann, Benedikt L., Alayón, Rebeca, Bergé, Daniel, Coll, Montserrat, Eslava, Jairo Santiago García, Pérez Sánchez, Ezequiel, Llimona, Carla, Macias, Cristina, and Mané, Anna

Subjects
PSYCHOSES, POST-traumatic stress, EMOTIONAL trauma
Abstract

Keywords: first episode psychosis; psychological trauma; post-psychotic posttraumatic stress; comorbidity; EMDR therapy; treatment as usual EN first episode psychosis psychological trauma post-psychotic posttraumatic stress comorbidity EMDR therapy treatment as usual 1 1 1 04/17/20 20200414 NES 200414 An author's name was incorrectly spelled as "Daniel Vergé" in the FEP-EMDR Research Group section. First episode psychosis, psychological trauma, post-psychotic posttraumatic stress, comorbidity, EMDR therapy, treatment as usual. [Extracted from the article]

Published
2020
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49. Supporting employees with mental illness and reducing mental illness-related stigma in the workplace: an expert survey

Author

Hogg, Bridget, Moreno-Alcázar, Ana, Tóth, Mónika Ditta, Serbanescu, Ilinca, Aust, Birgit, Leduc, Caleb, Paterson, Charlotte, Tsantilla, Fotini, Abdulla, Kahar, Cerga-Pashoja, Arlinda, Cresswell-Smith, Johanna, Fanaj, Naim, Meksi, Andia, Ni Dhalaigh, Doireann, Reich, Hanna, Ross, Victoria, Sanches, Sarita, Thomson, Katherine, Van Audenhove, Chantal, Pérez, Victor, Arensman, Ella, Purebl, Gyorgy, Amann, Benedikt L., O’Connor, Ainslie, Szekely, Andras, LaMontagne, Anthony, Como, Ariel, Dushaj, Arilda, Doukani, Asmae, Justicia, Azucena, Greiner, Birgit A., Lockwood, Chris, O’Connor, Cliodhna, McDaid, David, Kim, Dooyoung, Williamson, Eileen, Griffin, Eve, Coppens, Evelien, Burazeri, Genc, Qirjako, Gentiana, Davey, Grace, van Weeghel, Jaap, Eustace, Joe, Kilroy, Joseph, Hug, Juliane, Kolves, Kairi, Mulcahy, Karen, Michell, Karen, Wahlbeck, Kristian, de Winter, Lars, Cox, Laura, D’Alessandro, Luigia, Maxwell, Margaret, Reavley, Nicola, Trembeczky, Peter, Corcoran, Paul, Rugulies, Reiner, Benson, Ruth, Rapeli, Saara, Ihinonvien, Sarah, Mustafa, Sevim, Mathieu, Sharna, Hackel, Stefan, King, Tanya, Hegerl, Ulrich, Scott, Vanda, and Orchard, Wendy

Subjects
DISORDERS, Clinical Neurology, Anxiety, Expert survey, HEALTH-RELATED STIGMA, H Social Sciences, RA0421 Public health. Hygiene. Preventive Medicine, Pharmacology (medical), Workplace, COGNITIVE-BEHAVIORAL THERAPY, Biological Psychiatry, Psychiatry, WORK, Science & Technology, Depression, SME, General Medicine, CARE, Stigma, Psychiatry and Mental health, PROMOTION, Mental illness, PREVENTION INTERVENTIONS, Neurosciences & Neurology, CONSENSUS, Life Sciences & Biomedicine
Abstract

An expert survey was designed to support the development of a workplace-based multi-country intervention tackling depression, anxiety, and mental illness-related stigma in small- and medium-sized enterprises (SMEs). Academic experts and representatives of SME organisations, specific sector organisations, labour or advocacy groups, and occupational health organisations, were contacted across eight European countries and Australia. The survey comprised closed and open text questions to assess expert opinion about interventions for employees with mental health difficulties, interventions supporting their managers, and anti-stigma interventions. The survey was available in six languages. The online platform Qualtrics was used for data collection. Quantitative data was analysed through descriptive statistics and qualitative data was analysed through thematic analysis. Sixty-five of 146 experts responded, representing a 42% response rate. Results showed only 26.2% of experts agreed that employees could speak openly about mental health issues, and 81.5% of experts indicated a large or medium unmet need for support for employees with mental health issues. Psychoeducational materials, face-to-face workshops and interventions based on cognitive behavioural therapy were ranked most likely to be taken up by employees. Experts rated as most useful for managers' guidelines on how to act if an employee has mental health issues (67.7%). The greatest number of experts indicated workshops of people with lived experience of mental illness (80.0%) and awareness campaigns (78.5%) were most required to tackle stigma. Responses were consistent between experts from different countries and areas of expertise. Experts in this multinational survey assessed that interventions supporting mental health in the workplace and tackling stigma are greatly needed. A multicomponent intervention with a wide range of materials and tools is supported. ispartof: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE vol:273 issue:3 ispartof: location:Germany status: Published online

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50. Brain structural changes in the basal ganglia in heavy cannabis users: a VBM study

Author

Moreno-Alcázar, Ana, Gonzalvo, Begoña, Canales Rodriguez, Erick Jorge, Blanco, Laura, Bachiller, Diana, Romaguera, Anna, Monté-Rubio, Gemma C, Roncero, Carlos, McKenna, Peter J, and Pomarol-Clotet, Edith

Subjects
cannabis, basal ganglia, long-term users, voxel-based morphometry, MRI
Abstract

Structural imaging studies of cannabis users have found evidence of both cortical and subcortical volume reductions, especially in cannabinoid receptor-rich regions such as the hippocampus and amygdala. However, the findings have not been consistent. In the present study, we examined a sample of adult heavy cannabis users without other substance abuse to determine whether long-term use is associated with brain structural changes, especially in the subcortical regions. Method: We compared the gray matter volume of 14 long-term, heavy cannabis users with non-using controls. To provide robust findings, we conducted two separate studies using two different MRI techniques. Each study used the same sample of cannabis users and a different control group, respectively. Both control groups were independent of each other. First, whole-brain voxel-based morphometry (VBM) was used to compare the cannabis users against 28 matched controls (HC1 group). Second, a volumetric analysis of subcortical regions was performed to assess differences between the cannabis users and a sample of 100 matched controls (HC2 group) obtained from a local database of healthy volunteers. Results: The VBM study revealed that, compared to the control group HC1, the cannabis users did not show cortical differences nor smaller volume in any subcortical structure but showed a cluster (p < 0.001) of larger GM volume in the basal ganglia, involving the caudate, putamen, pallidum, and nucleus accumbens, bilaterally. The subcortical volumetric analysis revealed that, compared to the control group HC2, the cannabis users showed significantly larger volumes in the putamen (p = 0.001) and pallidum (p = 0.0015). Subtle trends, only significant at the uncorrected level, were also found in the caudate (p = 0.05) and nucleus accumbens (p = 0.047). Conclusions: This study does not support previous findings of hippocampal and/or amygdala structural changes in long-term, heavy cannabis users. It does, however, provide evidence of basal ganglia volume increases.

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