1. Feasibility and Health Benefits of an Individualized Physical Activity Intervention in Women With Metastatic Breast Cancer: Intervention Study
- Author
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Delrieu, Lidia, Pialoux, Vincent, Pérol, Olivia, Morelle, Magali, Martin, Agnès, Friedenreich, Christine, Febvey-Combes, Olivia, Pérol, David, Belladame, Elodie, Clémençon, Michel, Roitmann, Eva, Dufresne, Armelle, Bachelot, Thomas, Heudel, Pierre Etienne, Touillaud, Marina, Trédan, Olivier, and Fervers, Béatrice
- Subjects
Information technology ,T58.5-58.64 ,Public aspects of medicine ,RA1-1270 - Abstract
BackgroundThere is limited knowledge regarding the potential benefits of physical activity in patients with metastatic breast cancer. ObjectiveThe Advanced stage Breast cancer and Lifestyle Exercise (ABLE) Trial aimed to assess the feasibility of a physical activity intervention in women with metastatic breast cancer and to explore the effects of physical activity on functional, psychological, and clinical parameters. MethodsThe ABLE Trial was a single-arm, 6-month intervention study with a home-based, unsupervised, and personalized walking program using an activity tracker. At baseline and 6 months, we assessed anthropometrics, functional fitness, physical activity level, sedentary behavior, quality of life, fatigue, and tumor progression. Paired proportions were compared using the McNemar test and changes of parameters during the intervention were analyzed using the Wilcoxon signed-rank test, the Mann-Whitney test, and Spearman rank correlations. ResultsOverall, 49 participants (mean age 55 years; recruitment rate 94%) were enrolled and 96% adhered to the exercise prescription (attrition rate 2%). Statistically significant improvements in the 6-minute walking distance test (+7%, P
- Published
- 2020
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