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3. Biological and prognostic differences between symptomatic colorectal carcinomas and those detected by screening

Author

Quintana Lopez, José María, Mañas, Marisa Baré, Bautista, Maximino Redondo, Pérez de la Blanca, Eduardo Briones, Fernández de Larrea Baz, Nerea, Eizaguirre, Cristina Sarasqueta, Martínez, Antonio Escobar, Ruiz, Francisco Rivas, Morales-Suárez-Varela, María M., Blasco Amaro, Juan Antonio, Gonzalez, Isabel del Cura, Madariaga, Inmaculada Arostegui, González, Amaia Bilbao, Hernandez, Nerea González, García-Gutiérrez, Susana, Guerrero, Iratxe Lafuente, Larracoechea, Urko Aguirre, Calzada, Miren Orive, Corral, Josune Martin, Anton-Ladislao, Ane, Torà, Nuria, Pont, Marina, Martínez del Prado, María Purificación, Totorikaguena, Alberto Loizate, Estevez, Ignacio Zabalza, Alustiza, José Errasti, Gimeno García, Antonio Z., Aramburu, Santiago Lázaro, Serrano, Mercè Comas, Enríquez Navascues, José María, Galan, Carlos Placer, Perales, Amaia, Valmaña, Iñaki Urkidi, Erro Azkárate, José María, Lizarribar, Enrique Cormenzana, Muñoa, Adelaida Lacasta, Pibernat, Pep Piera, Cuevas, Elena Campano, Sotelo Gómez, Ana Isabel, Abril, Segundo Gómez, Medina-Cano, F., Alcaide, Julia, Del Rey-Moreno, Arturo, Alcántara, Manuel Jesús, Campo, Rafael, Casalots, Alex, Pericay, Carles, Gil, María José, Pera, Miquel, Collera, Pablo, Espinàs, Josep Alfons, Martínez, Mercedes, Espallargues, Mireia, Almazán, Caridad, Lindenbaum, Paula Dujovne, Fernández-Cebrián, José María, Fernández, Rocío Anula, Mayol Martínez, Julio Ángel, Cid, Ramón Cantero, Labajo, Héctor Guadalajara, Garceau, María Heras, Olmo, Damián García, Montalvo, Mariel Morey, Mar, Javier, Téllez, Teresa, Abitei, Cristina, Padilla-Ruiz, María del Carmen, Rivas-Ruiz, Francisco, Fúnez, Rafael, Pereda, Teresa, Rodrigo, Isabel, Baré, María Luisa, Morales Suárez-Varela, María Manuela, Zabalza, Iñaki, Sánchez del Charco, Matilde, Borrero Martín, Juan José, García del Moral, Raimundo, Escobar, Antonio, Quintana, José María, Aguirre, Urko, and Redondo, Maximino

Published
2019
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6. Occupational Exposure to Chlorinated and Petroleum Solvents and Mycosis Fungoides

Author

Morales-Suárez-Varela, Maria M., Olsen, Jorn, Villeneuve, Sara, Johansen, Preben, Kaerlev, Linda, Llopis-González, Agustin, Wingren, Gun, Hardell, Lennart, Ahrens, Wolfgang, Stang, Andreas, Merletti, Franco, Gorini, Giuseppe, Aurrekoetxea, Juan José, Févotte, Joëlle, Cyr, Diane, and Guénel, Pascal

Published
2013

15. Occupational Risks for Uveal Melanoma Results from a Case-Control Study in Nine European Countries

Author

Lutz, Jean-Michel, Cree, Ian, Sabroe, Svend, Kvist, Tine Kajsa, Clausen, Lene Bjørk, Afonso, Noemia, Ahrens, Wolfgang, Ballard, Terri J., Bell, Janine, Cyr, Diane, Eriksson, Mikael, Févotte, Joëlle, Guénel, Pascal, Hardell, Lennart, Jöckel, Karl-Heinz, Miranda, Ana, Merletti, Franco, Morales-Suarez-Varela, Maria M., Stengrevics, Aivars, and Lynge, Elsebeth

Published
2005
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20. Risk scores to predict mortality 2 and 5 years after surgery for colorectal cancer in elderly patients.

Author

González, Nerea, Loroño, Ane, Aguirre, Urko, Lázaro, Santiago, Baré, Marisa, Redondo, Maximino, Briones, Eduardo, Sarasqueta, Cristina, Bilbao, Amaia, de Larrea, Nerea Fernández, Quintana, José María, for the REDISSEC-CARESS/CCR group, Quintana, Jose María, Escobar, Antonio, Rivas, Francisco, Morales-Suárez-Varela, Maria M., Blasco, Juan Antonio, del Cura, Isabel, Arostegui, Inmaculada, and Barrio, Irantzu

Subjects
COLORECTAL cancer, ONCOLOGIC surgery, OLDER patients, PROCTOLOGY, CANCER patients, PUBLIC hospitals
Abstract

Background: The aim of this study was to identify predictors of mortality in elderly patients undergoing colorectal cancer surgery and to develop a risk score. Methods: This was an observational prospective cohort study. Individuals over 80 years diagnosed with colorectal cancer and treated surgically were recruited in 18 hospitals in the Spanish National Health Service, between June 2010 and December 2012, and were followed up 1, 2, 3, and 5 years after surgery. Sociodemographic and clinical data were collected. The primary outcomes were mortality at 2 and between 2 and 5 years after the index admission. Results: The predictors of mortality 2 years after surgery were haemoglobin ≤ 10 g/dl and colon locations (HR 1.02; CI 0.51–2.02), ASA class of IV (HR 3.55; CI 1.91–6.58), residual tumour classification of R2 (HR 7.82; CI 3.11–19.62), TNM stage of III (HR 2.14; CI 1.23–3.72) or IV (HR 3.21; CI 1.47–7), LODDS of more than − 0.53 (HR 3.08; CI 1.62–5.86)) and complications during admission (HR 1.73; CI 1.07–2.80). Between 2 and 5 years of follow-up, the predictors were no tests performed within the first year of follow-up (HR 2.58; CI 1.21–5.46), any complication due to the treatment within the 2 years of follow-up (HR 2.47; CI 1.27–4.81), being between 85 and 89 and not having radiotherapy within the second year of follow-up (HR 1.60; CI 1.01–2.55), no colostomy closure within the 2 years of follow-up (HR 4.93; CI 1.48–16.41), medical complications (HR 1.61; CI 1.06–2.44), tumour recurrence within the 2 years of follow-up period (HR 3.19; CI 1.96–5.18), and readmissions at 1 or 2 years of follow-up after surgery (HR 1.44; CI 0.86–2.41). Conclusion: We have identified variables that, in our sample, predict mortality 2 and between 2 and 5 years after surgery for colorectal cancer older patients. We have also created risks scores, which could support the decision-making process. Trial registration: ClinicalTrials.gov, NCT02488161. [ABSTRACT FROM AUTHOR]

Published
2021
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21. Predictors of readmission and reoperation in patients with colorectal cancer.

Author

Quintana, José M., Anton-Ladislao, Ane, Lázaro, Santiago, Gonzalez, Nerea, Bare, Marisa, de Larrea, Nerea Fernandez, Redondo, Maximino, Briones, Eduardo, Escobar, Antonio, Sarasqueta, Cristina, Garcia-Gutierrez, Susana, The REDISSEC CARESS-CCR (Results and Health Services Research in Colorectal Cancer)- group, Quintana, Jose María, Baré, Marisa, Fernández-de-Larrea, Nerea, Rivas, Francisco, Morales-Suárez-Varela, Maria M., Blasco, Juan Antonio, del Cura, Isabel, and Arostegui, Inmaculada

Subjects
CLINICAL prediction rules, COLORECTAL cancer, SURGICAL complications, PATIENT readmissions, RECTAL cancer, CANCER patients, REOPERATION, RESEARCH funding, STATISTICAL models, ODDS ratio, LONGITUDINAL method
Abstract

Purpose: To assess the impact of readmission and reoperation on colon or rectal cancer patients in clinical and patient-reported outcome measures (PROMs) and to identify predictors of these events up to 1 year after surgery.Methods: Prospective cohort study of patients diagnosed with colon or rectal cancer who underwent surgery at 1 of 22 hospitals. Medical history, clinical parameters, and PROMs were evaluated as possible predictors. Multivariable multilevel logistic regression and survival models were used in the analyses to create the clinical prediction rules. Models were developed in a derivation sample and validated in a different sample.Results: Readmission and reoperation were related to clinical outcomes and changes in some PROMs. Predictors of readmission in colon cancer were ASA class (odds ratio (OR) 4.5), TNM (OR for TNM III 3.24, TNM IV 4.55), evidence of residual tumor (R2) (OR 3.96), and medical (OR 1.96) and infectious (OR 2.01) complications within 30 days after surgery, while for rectal cancer, the predictors identified were age (OR 1.03), R2 (OR 6.48), infectious complications within 30 days (OR 2.29), hemoglobin (OR 3.26), lymph node ratio (OR 2.35), and surgical complications within 1 month (OR 3.04). Predictors of reoperation were TNM IV (OR 5.06), surgical complications within 30 days (OR 1.98), and type and site of tumor (OR 1.72) in colon cancer and being male (OR 1.52), age (OR 1.80), stoma (OR 1.87), and surgical complications within 1 month (OR 1.95) in rectal cancer.Conclusions: Our clinical prediction rule models are easy to use and could help to develop and implement interventions to reduce preventable readmissions and reoperations.Trial Registration: https://clinicaltrials.gov/ct2/show/NCT02488161 Identifier: NCT02488161. [ABSTRACT FROM AUTHOR]

Published
2020
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22. Outcomes of open versus laparoscopic surgery in patients with colon cancer

Author

Quintana, José M., primary, Antón-Ladisla, Ane, additional, González, Nerea, additional, Lázaro, Santiago, additional, Baré, Marisa, additional, Fernández de Larrea, Nerea, additional, Redondo, Maximino, additional, Briones, Eduardo, additional, Escobar, Antonio, additional, Sarasqueta, Cristina, additional, García-Gutierrez, Susana, additional, Quintana López, Jose María, additional, Mañas, Marisa Baré, additional, Bautista, Maximino Redondo, additional, Pérez de la Blanca, Eduardo Briones, additional, Fernández de Larrea Baz, Nerea, additional, Eizaguirre, Cristina Sarasqueta, additional, Martínez, Antonio Escobar, additional, Ruiz, Francisco Rivas, additional, Morales-Suárez-Varela, Maria M., additional, Blasco Amaro, Juan Antonio, additional, González, Isabel del Cura, additional, Madariaga, Inmaculada Arostegui, additional, González, Amaia Bilbao, additional, Hernández, Nerea González, additional, García-Gutiérrez, Susana, additional, Guerrero, Iratxe Lafuente, additional, Larracoechea, Urko Aguirre, additional, Calzada, Miren Orive, additional, Corral, Josune Martin, additional, Antón-Ladislao, Ane, additional, Torà, Núria, additional, Pont, Marina, additional, Martínez del Prado, María Purificación, additional, Totorikaguena, Alberto Loizate, additional, Estévez, Ignacio Zabalza, additional, Alustiza, José Errasti, additional, Gimeno García, Antonio Z., additional, Aramburu, Santiago Lázaro, additional, Serrano, Mercè Comas, additional, Enríquez Navascues, Jose María, additional, Galán, Carlos Placer, additional, Perales, Amaia, additional, Valmaña, Iñaki Urkidi, additional, Erro Azkárate, Jose María, additional, Lizarribar, Enrique Cormenzana, additional, Muñoa, Adelaida Lacasta, additional, Pibernat, Pep Piera, additional, Cuevas, Elena Campano, additional, Sotelo Gómez, Ana Isabel, additional, Gómez-Abril, Segundo, additional, Medina-Cano, F., additional, Alcaide, Julia, additional, Del Rey-Moreno, Arturo, additional, Alcántara, Manuel Jesús, additional, Campo, Rafael, additional, Casalots, Alex, additional, Pericay, Carles, additional, Gil, Maria José, additional, Pera, Miquel, additional, Collera, Pablo, additional, Espinàs, Josep Alfons, additional, Martínez, Mercedes, additional, Espallargues, Mireia, additional, Almazán, Caridad, additional, Lindenbaum, Paula Dujovne, additional, Fernández-Cebrián, José María, additional, Fernández, Rocío Anula, additional, Mayol Martínez, Julio Ángel, additional, Cid, Ramón Cantero, additional, Labajo, Héctor Guadalajara, additional, Garceau, María Heras, additional, Olmo, Damián García, additional, Montalvo, Mariel Morey, additional, and Mar, Javier, additional

Published
2018
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23. Autores

Author

Abecia Inchaurregui, Luis Carlos, Abreu Rodríguez, Rossana, Aguinaga Ontoso, Enrique, Aibar Remón, Carlos, Alberdi Sudupe, Jesús, Alfonso Sánchez, José Luis, Alguacil Ojeda, Juan, Almaraz Gómez, Ana, Altet Gómez, María Neus, Álvarez Marante, Roberto, Álvarez-Dardet Díaz, Carlos, Álvarez-Ruiz, Juan Carlos, Amezcua Prieto, Carmen, Aranaz Andrés, Jesús M.ª, Aranceta Bartrina, Javier, Arcos González, Pedro, Arévalo Morales, M.ª Pilar, Arias Rodríguez, Ángeles, Armadans Gil, Lluís, Badenier Bustamante, Osvaldo, Ballina García, Francisco Javier, Baltar Trabazo, José Manuel, Banegas Banegas, José Ramón, Barros Dios, Juan Miguel, Bes-Rastrollo, Maira, Bolúmar Montrull, Francisco, Borràs López, Eva, Brugos Larumbe, Antonio, Bueno Cavanillas, Aurora, Caamaño Isorna, Francisco, Calle Purón, María Elisa, Calleja Cabeza, Patricia, Campayo Rojas, Francisco Javier, Campins Martí, Magda, Carlos Chillerón, Silvia, Carrasco Garrido, Pilar, Castro Delgado, Rafael, Castro Hernández, Beatriz, Conde Herrera, Manuel, Corella Piquer, Dolores, Cores Calvo, Juan, Crous Bou, Marta, Davó Blanes, M.ª Carmen, de Irala Estévez, Jokin, de Juanes Pardo, José Ramón, del Barrio Fernández, José Luis, del Rey Calero, Juan, Delgado Rodríguez, Miguel, Díaz Molina, Carmen, Dierssen Sotos, Trinidad, Díez Sebastián, Jesús, Díez-Gañán, Lucía, Domínguez García, Ángela, Domínguez Rojas, Vicente, Donat-Vargas, Carolina, Doreste Alonso, Jorge Luis, Duran Jordà, Xavier, Escribá Aguir, Vicenta, Esguep Sarah, Alfredo, Espigares García, Miguel, Espigares Rodríguez, Elena, Farouk Allam, Mohamed, Fernández Muñoz, Esteve, Fernández-Crehuet Navajas, Joaquín, Fernández-Crehuet Navajas, Rafael, Fernández-Crehuet Serrano, José Luis, Fernández-Crehuet Serrano, Pablo, Ferreira Herdeiro, María Teresa, Figueiras Guzmán, Adolfo, Fuentes Almendras, Margarita, Gallardo Pino, Carmen, García Barbero, Milagros, García Benavides, Fernando, García Caballero, Juan, García de la Hera, Manuela, García López, Eva María, García Martín, Miguel, García Rodríguez, Antonio, Gea Sánchez, Alfredo, Gestal Otero, Juan Jesús, Gestal Romaní, Santiago, Gil de Miguel, Ángel, Gil Prieto, Ruth, Gil-González, Diana, Gili Miner, Miguel, Gómez Acebo, Inés, Gómez-Aracena, Jorge, Gómez-Gracia, Enrique, González Iglesias, Marta Clara, Graciani Pérez-Regadera, Auxiliadora, Guallar Castillón, Pilar, Guillén Grima, Francisco, Guillén Solvas, José Francisco, Gutiérrez Bedmar, Mario, Gutiérrez-Fisac, Juan Luis, Harris, Meggan, Henríquez Sánchez, Patricia, Hernández Aguado, Ildefonso, Hernández Mejía, Radhamés, Herruzo Cabrera, Rafael, Herruzo Priego, Irene, Iglesias Amorín, José Luis, Jiménez García, Rodrigo, Jiménez Mejías, Eladio, Jiménez Moleón, José Juan, Jurado Chacón, Dolores, Lana Pérez, Alberto, Lardelli Claret, Pablo, Latorre-Arteaga, Sergio, Lecuona Fernández, María, Llinás Santacreu, Gilberto, Llopis González, Agustín, Llorca Díaz, Javier, López de Andrés, Ana, López García, Esther, López-Gigosos, Rosa María, López González, María Luisa, López Jurado, Lázaro, López-del Burgo, Cristina, Lumbreras Lacarra, Blanca, Luna del Castillo, Juan de Dios, Malvar Pintos, Alberto, Mariscal Larrubia, Alberto, Martín Moreno, José María, Martín Sánchez, Vicente, Martín-Calvo, Nerea, Martínez-González, Miguel Ángel, Martínez Ruiz, Virginia, Martínez Vizcaíno, Vicente, Mendiola Olivares, Jaime, Miqueleiz Autor, Estrella, Monasterio Otero, Adolfo Alejandro, Monge Corella, Susana, Montes Martínez, Agustín, Morales Suárez-Varela, María M., Moreno Abril, Obdulia, Moreno Roldán, Elena, Moya Geromini, Ángeles, Muñiz Saborido, José Ramón, Muñoz Bravo, Carlos, Navarrete Muñoz, Eva María, Olmedo Requena, Rocío, Ortiz Moncada, Rocío, Otero Cordeiro, Francisco Javier, Pastor Valero, María, Peña Sánchez de Rivera, José María, Pértega Díaz, Sonia, Pita Fernández, Salvador, Porta Serra, Miquel, Portolés Reparaz, Olga, Regidor Poyatos, Enrique, Ribas Barba, Lourdes, Río Sánchez, Isabel, Rodríguez Álvarez, Cristobalina, Rodríguez Arenas, M.ª Ángeles, Rodríguez Artalejo, Fernando, Rodríguez Cundín, Paz, Rodríguez Martínez, Marisol, Ronda Pérez, Elena, Rosell Aguilar, Ignacio, Ruano Rodríguez, Cristina, Ruiz Cantero, María Teresa, Ruiz-Canela López, Miguel, Salleras Sanmartí, Lluís, Saltó Cerezuela, Esteve, Sánchez Fernández, Luis Vicente, Sánchez Villegas, Almudena, Sastre Gervás, Isabel, Serra Majem, Lluís, Serrano del Castillo, Amparo, Sillero Arenas, María, Sorlí Guerola, José Vicente, Sotodosos Carpintero, Mercedes, Takkouche, Bahi, Taracido Trunk, Margarita, Tardón García, Adonina, Teijeiro Dacal, María José, Toledo Atucha, Estefanía A., Torner Gracia, Nuria, Torres Cantero, Alberto Manuel, Valcárcel Rivera, Yolanda, Vaqué Rafart, Josep, Villar Álvarez, Fernando, Vioque López, Jesús, and Vizcaíno Alcaide, María José

Published
2016
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27. Occupational factors and risk of adult bone sarcomas: A multicentric case-control study in Europe

Author

Merletti, Franco, primary, Richiardi, Lorenzo, additional, Bertoni, Franco, additional, Ahrens, Wolfgang, additional, Buemi, Antoine, additional, Costa-Santos, Cristina, additional, Eriksson, Mikael, additional, Guénel, Pascal, additional, Kaerlev, Linda, additional, Jöckel, Karl-Heinz, additional, Llopis-Gonzalez, Agustin, additional, Merler, Enzo, additional, Miranda, Ana, additional, Morales-Suárez-Varela, Maria M., additional, Olsson, Håkan, additional, Fletcher, Tony, additional, and Olsen, Jorn, additional

Published
2005
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29. The Effect of the Covid-19 Lockdown on Air Quality in Three Italian Medium-Sized Cities.

Author

Donzelli, Gabriele, Cioni, Lorenzo, Cancellieri, Mariagrazia, Llopis Morales, Agustin, and Morales Suárez-Varela, Maria M.

Subjects
STAY-at-home orders, AIR quality, COVID-19, ECONOMIC impact of disease, AIR pollution control, PARTICULATE matter, AIR pollutants
Abstract

Despite the societal and economic impacts of the COVID-19 pandemic, the lockdown measures put in place by the Italian government provided an unprecedented opportunity to increase our knowledge of the effect transportation and industry-related emissions have on the air quality in our cities. This study assessed the effect of reduced emissions during the lockdown period, due to COVID-19, on air quality in three Italian cities, Florence, Pisa, and Lucca. For this study, we compared the concentration of particulate matter PM10, PM2.5, NO2, and O3 measured during the lockdown period, with values obtained in the same period of 2019. Our results show no evidence of a direct relationship between the lockdown measures implemented and PM reduction in urban centers, except in areas with heavy traffic. Consistent with recently published studies, we did, however, observe a significant decrease in NO2 concentrations among all the air-monitoring stations for each city in this study. Finally, O3 levels remained unchanged during the lockdown period. Of note, there were slight variations in the meteorological conditions for the same periods of different years. Our results suggest a need for further studies on the impact of vehicular traffic and industrial activities on PM air pollution, including adopting holistic source-control measures for improved air quality in urban environments. [ABSTRACT FROM AUTHOR]

Published
2020
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30. Letters to the Editor.

Author

Dempsey, Delia A., Stewart, Susan L., Morales-Suárez-Varela, Maria M., Olsen, Jorn, Bille, Camilla, and Christensen, Kaare

Published
2006

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